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Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiii
Foreword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xxvii
Foreword to the First Edition .xxix
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xxxi
SECTION 1
Foundation Issues
Section Editor: L. Michael Posey
1. Pharmacoeconomics: Principies,Methods, and Applications 6) . . . . . . . . . . . . . . . . .. 1Lisa Sanehez Trask
2. Health Outcomes and Health-Related
Quality of Life e 3
Stephen Joe/ Coons
3. Health Literacy and Medication Use CD . . . . . . . . .. 5Oralia V. Bazaldua and Sunil Kripalani
4. Cultural Competency CD . . . . . . . . . . . . . . . . . . . . . . . 7Jeri J. Sias, Amanda M. Loya, José O. Rivera,
Arthur A. Islas, and Ulysses]. Urquidi
5. Principies and Practicesof Medication Safety CD . . . . . . . . . . . . . . . . . . . . . . . . 9
Seott M. Mark, Jeffrey D. Little,Sarah E. Adkins, and Robert J. Weber
6. Evidence- Based Medicine CD 11
Elaine Chiquette and L. Miehae/ Posey
7.Documentation of Pharmacy Services (i\ . . . . . . .. 13George E. MaeKinnon III and Neil J. MaeKinnon
8. ClinicalPharmacokinetics and
Pharmacodynamics e. . . . . . . . . . . . . . . . . . . . . . .. 15
Larry A. Bauer
9. Pharmacogenetics (\\ . . . . . . . . . . . . . . . . . . . . . . . .. 17
Larisa H. Cavallari and Y. W. Francis Lam
10. Pediatrics 4' 19
Milap C. Nahata and Carol Taketomo
11. GeriatricsCD oo 21Emily R. Hajjar, Shelly L. Gray,David R.P. Guay, Catherine 1. Starner,
Steven M. Handler, and Joseph T. Hanlon
12. Palliative Care . 23
JillAstolfi
13. Pharmacoepidemiology CD . . . . . . . . . . . . . . . . . . . . 25
Andy Stergaehis,Thomas K. Hazlet,and DeniseBoudreau
14. Clinical Toxicology . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
Peter A. Chyka
15. Emergency Preparedness: Identification and
Management of Biologic Exposures &. . . . . . . . . . 51
Colleen M. Terriff, Jason E. Brouillard,Lisa T. Costanigro, and Jessiea S. Oftebro
16. Emergency Preparedness: Identification and
Management of Chemical and RadiologicExposures ~ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
GreeneShepherd and Riehard B. Sehwartz
SECTION 2
Cardiovascular Disorders
SectionEditor:RobertL.Talbert
17. Cardiovascular Testing. . . . . . . . . . . . . . . . . . . . . . . . 55
Riehard A. Lange and L. David Hillis
1 8. Cardiac Arrest . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
Jeffrey F. Barletta and Jeffrey L. Wilt
19. Hypertension . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
Joseph J. Saseen and Erie ]. Maclaughlin
20. Systolic Heart Failure . . . . . . . . . . . . . . . . . . . . . . .. 137
Robert B. Parker and Larisa H. Cavallari
21. Diastolic Heart Failure and the
Cardiomyopathies . . . . . . . . . . . . . . . . . . . . . . . . . .. 173
Jean M. Nappi and Robert L. Page II
'" The completechapter,learningobjectives,and other resourcescan be found at www.pharmacotherapyonline.com.
22. Acute DecompensatedHeart Failureo o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o 191
lo EoRodgers and Craig R. Lee
23. Ischemic Heart Diseaseo . . . . ooooooooooo. . . . . . . 209
Robert L. Talbert
24. Acute Coronary Syndromes. o oo 241
Sarah Ao Spinler and Simon De Denus
25. The Arrhythmias o o o o o o o o o o o o . . . . . . o o o o o o o o o o 273
Cynthia Ao Sanoski and lerry L. Bauman
26. Venous Thromboembolismo o o o o o.. o o o o o o o o o o 0311
Daniel M. Witt, Edith AoNuteseu,and Stuart T. Haines
27. Stroke o o o o o . . o o o o o o o o o o o . . . . o . o o o o o o o o o o o o . . 353
Susan C. Fagan and David C. Hess
28. Dyslipidemiao o o o o o o o.. o. o o o o o o o o o o o o o. o. o o o o 365Robert L. Talbert
29. Peripheral Arterial Disease. . . o oo oo oo oo o . . . . . o . 389Barbara J. Hoeben and Robert L. Talbert
30. Use ofVasopressors andInotropes in the Pharmacotherapyof Shock. o o o o o o o o o o o . o o o o o o o o o o o o . . . . o o o o o o o 399
Robert Maclaren, Maria lo Rudis,
and loseph F. Dasta
31. Hypovolemic Shock. o o o o o o o o o o o... o o o o o o o o o o o 421Brian L. Erstad
SECTION 3
RespiratoryOisordersSection Editor: Robert L. Talbert
32. Introduction to PulmonaryFunctionTesting6) o o o o o o o o o o o o o o o . . . . o o o o o o 437lay l. Peters and Stephanie M. Levine
33. Asthma oo oo . . o oo o . . . . . . . . . . . o . . . . . . . . . o oo oo 439
H. William Kel/y and Christine Ao Sorkness
34. Chronic ObstructivePulmonary Disease . . o o o o o o o o o o o o o o o o o o o o . o o . 471
Dennis M. Williams and Sharya Vo Bourdet
35. Pulmonary Arterial Hypertension . o. . . . . . . . . . . 497Rebecca Moote, Rebecca L. Attridge,and Deborah 'o Levine
36. Drug- Induced Pulmonary Disease . . . . . . . . . . . . . 511
Hengameh HoRaissy, Miehel/e Harkins,and Patrieia L. Marshik
37. Cystic Fibrosis .. .. .. . ooo.. .. . .. .. .. . .. . . . . . o525
ChaninC. Wrightand YolandaY. Vera
SECTION 4
Gastrointestinal Oisorders
SectionEditor:Joseph T. DiPiro
38. Evaluation of the GastrointestinalTract. . . . . . . . . . . . . . oo. . . . . . . oooo. . . . . ooooo. . 539
Keith M. Olsen and Grant FoHutehins
39. Gastroesophageal Reflux Disease o o o o o o o . . . o . o o 549Dianne B. Williams and Robert R. Sehade
40. Peptic Ulcer Disease . . . . . o o o . . o o o o o o . . o o o o o o . 563
Rosemary R. Berardi and Randolph VoFugit
41. Inflammatory BowelDisease . . . . . . . . . . . oo. o. o. 587Brian Ao Hemstreet
42. Nausea and Vomiting o o. . . o . o oo . . . . o oo oo o . . . . 607
Cecily V. DiPiro and RobertJ. 19noffo
43. Diarrhea, Constipation, and IrritableBowelSyndrome o o o. 621
Patricia Ho Powel/ and Virginia Ho Fleming
44. Portal Hypertension and Cirrhosiso o o o o . o o o o o o o 639
lulie Mo Sease
45. Drug-Induced Liver Disease o. ooooo. . . oo. . o. . . 659
William R. Kirehain and Rondal/ E. Al/en
46. Pancreatitis. o o o o . . . o . o o o o o o . . . o o o o . . . o o o o o . . 669
Seott Bolestaand PatriciaAoMontgomery
47. Vira! Hepatitis .. .. .. . oo.. .. .. . ooo.. .. ooo.. . . 685
Paulina Deming
48. Drug Therapy Individualization inPatients with Hepatic Disease andGenetic Alterations in DrugMetabolizing Activity o. . . ooooo. o. . . . . o. . . . . . . 705YoWoFrancis Lam
49. Celiac Disease &.. o o o o o o o o.. o o o 0717
Robert Ao Mangione and Priti N. Patel
SECTION 5
Renal Oisorders
SectionEditor:GaryRoMatzke
50. Clinical Assessment of Kidney Function . . . . . . oo719
Thomas C. Dowling
51. Acute Kidney Injury . . . . . . . . . . . . o. . . . . . . . o. . . 741
William Dager and lenana Hali/ovie
52. Chronic Kidney Disease:Progression-Modifying Therapieso . o . . . o o o o o o o o 767
Vimal K. Derebail, Abhijit Vo Kshirsagar,
and Melanie Soloy
4\ The complete chapter,learningobjectives,and other resources can be found at www.pharmacotherapyonline.com.
53. Chronic Kidney Disease:Management of Complications . . . . . . . . . . . . . . . . 787
Joanna Q. Hudson
54. Hemodialysis and Peritoneal Dialysis 6) . . . 817Kevin M. Sowinski and Mariann D. Churchwell
55. Drug-Induced Kidney Disease. . . . . . . . . . . . . . . . . 819
Thomas D. Nolin and Jonathan Himmelfarb
56. Glomerulonephritis 837Alan H. Lau
57. Drug Therapy Individualization forPatients with Chronic Kidney Disease. . . . . . . . . . 861Gary R. Matzke
58. Disorders ofSodium and WaterHomeostasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873
James D. Coyle and Gary R. Matzke
59. Disorders of Calcium and PhosphorusHomeostasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891
Amy Barton Pai
60. Disorders of Potassium and MagnesiumHomeostasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909
Donald F. Brophy and Jane Frumin
61. Acid-Base Disorders . . . . . . . . . . . . . . . . . . . . . . . . . 923
John W. Devlin and Gary R. Matzke
-,, '., .~..
Neurologlc DisordersSection Editor: Barbara G. Wel/s
62. Evaluation ofNeurologic Illness 943Susan C. Fagan and Fenwick T. Nichols
63. Alzheimer's Disease. . . . . . . . . . . . . . . . . . . . . . . . . . 947
Patricia W. Slattum, Russell H. Swerdlow,
and Angela Massey Hill
64. Multiple Sclerosis. . . . . . . . . . . . . . . . . . . . . . . . .. . . 963
Jacquelyn L. Bainbridge and John R. Corboy
65. Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . 979Susan ]. Rogers and Jose E. Cavazos
66. Status Epilepticus. . . . . . . . . . . . . . . . . . . . . . . . . . . 1007
Stephanie]. Phelps,Collin A. Hovinga,and James w.Wheless
67. Acute Management oftheBrain Injury Patient. . . . . . . . . . . . . . . . . . . . . . . . . 1019
Bradley A. Boucher and Shelly D. Timmons
68. Parkinson's Disease. . . . . . . . . . . . . . . . . . . . . . . . . 1033
Jack]. Chen, Merlin V. Nelson,
and David M. Swope
69. Pain Management . . . . . . . . . . . . . . . . . . . . . . . . . . 1045
TerryJ. Baumann, Jennifer M. Strickland,and ChrisM. Herndon
70. Headache Disorders . . . . . . . . . . . . . . . . . . . . . . . . 1061
Deborah S. Minor
SECTION 7
psychiatric DisordersSection Editor: Barbara G. Wel/s
71. Evaluation of Psychiatric Illness . . . . . . . . . . . . .. 1077Mark E. Schneiderhan, Leigh Anne Nelson,and Stuart Munro
72. Childhood Disorders. . . . . . . . . . . . . . . . . . . . . . . . 1087
Julie A. Dopheide and StephenR. Pliszka
73. Eating Disorders 1101Steven C. Stoner
74. Substance-Related Disorders:Overview and Depressants, Stimulants,and Hallucinogens. . . . . . . . . . . . . . . . . . . . . . . . . . 1113
Paul L. Doering
75. Substance-Related Disorders: Alcohol,Nicotine, and Caffeine . . . . . . . . . . . . . . . . . . . . .. 1131
PaulL.Doeringand Robin Moorman U
76. Schizophrenia . 1147M. Lynn Crismon, Tami R. Argo,and Peter F. Buckley
77. Major Depressive Disorder 1173Christian]. Teter, Judith C. Kando,and Barbara G. Wells
78. Bipolar Disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . 1191
Shannon J. Drayton
79. Anxiety Disorders 1:Generalized Anxiety, Panic,and Social Anxiety Disorders. . . . . . . . . . . . . . . . . 1)09
Sarah T. Melton and Cynthia K. Kirkwood
80. Anxiety Disorders 11:Posttraumatic Stress Disorderand Obsessive-CompulsiveDisorder. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 1229
Cynthia K. Kirkwood, Usa B. Phipps,and Barbara G. Wells
81. Sleep Disorders. . . . . . . . . . . .. . . . . . . . . . . . . . . .. 1241
John M. Dopp and Bradley G. Phillips
82. Disorders Associated with
Intellectual Disabilities 8 . . . . . . . . . . . . . . . . . . . 1253
Nancy Brahm, Jerry Mckee, and Douglas Stewart
. The complete chapter,learningobjectives,and other resources can be found at www.pharmacotherapyonline.com.
SECTION8
Endocrinologic DisordersSection Editor: Robert L. Talbert
83. Diabetes Mellitus. . . . . . . . . . . . . . . . . . . . . . . . . . . 1255
Curtis 1. Triplitt and CharlesA. Reasner
84. Thyroid Disorders. . . . . . . . . . . . . . . . . . . . . . . . . . 1303
JacquelineJonklaasand Robert 1. Talbert
85. Adrenal Gland Disorders 1327
Steven M. Smith and John G. Gums
86. Pituitary Gland Disorders . . . . . . . . . 1345Amy Heck Sheehan,Jack A. Yanovski,and Karim Anton Calis
SECTION9
Gynecologic and ObstetricDlsorders
SectionEditor: Barbara C. We/ls
87. Pregnancy and Lactation:Therapeutic Considerations. . . . . . . . . . . . . . . . . . 1361Kristina E. Ward and Barbara M. O'Brien
88. Contraception . . . . . . . . . . . . . 1377Sarah P. Shrader, Kelly R. Ragucci,and VanessaA. Diaz
89. Menstruation-Related Disorders. . . . . . . . . . . . .. 1393
Elena M. Umland, Lara Carson Weinstein,and Edward M. Buchanan
90. Endometriosis . . . . . . . . . . . . . . . . 1409
Deborah A. Sturpe
91. Hormone Therapy in Women 1417Sophia N. Kalantaridou, Devra K. Dang,Susan R. Davis, and Karim Anton Calis
SECTION 10
UrologicDisordersSection Editor: L. Michael Posey
92. Erectile Dysfunction . . . . . . . . . . . . . . . . . . . . . . . . 1437
Mary Lee
93. Benign Prostatic Hyperplasia. . . . . . . . . . . . . . . . . 1455
Mary Lee
94. Urinary Incontinence . . . . . . . . . . . . . . . . . . . . . . . 1467
Eric S.Rovner, Jean Wyman,Thomas Lackner, and David R.P. Guay
SECTION 11
Immunologic Disorders
SectionEditor:Cary e Yee95. Function and Evaluation of the
Immune System . . 1487PhilipD. Hall,NicoleWeimertPilch,and DanielH. Atchley
96. Systemic Lupus Erythematosus andOther Collagen-Vascular Disorders 1505JeffreyC.Delafuenteand KimberlyA. Cappuzzo
97. Allergic and PseudoallergicDrug Reactions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1521
Lynne M. Sylvia and Joseph T. DiPiro
98. Solid-Organ Transplantation. . . . . . . . . . . . . . . .. 1537
Heather j. Johnson and Kristine S. Schonder
~'l 3 jr'11tnlngic Disorderc;
SectionEditor:L.Michael Posey
~~ Osteoporosis and Other MetabolicBone Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1559
Mary Beth O'Connell and Sheryl F. Vondracek
00 Rheumatoid Arthritis ... . . . 1583
Arthur A. Schuna
1 01 Osteoarthritis 1599
Lucinda M. Buys and Mary Elizabeth Elliott
01. Gout and Hyperuricemia. . . . . . . . . . . . . . . . . . .. 1621Michael E. Ernst and Elizabeth C. Clark
SECTION 13
Ophthalmicand OtolaryngologicalDisordersSection Editor: L. Michael Posey
103. Glaucoma . . . . . . . 1633
Richard G. Fiscella, Timothy S. Lesar,
and Deepak P. Edward
104. Allergic Rhinitis. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1649
j. RussellMay and Philip H. Smith
SECTION 14
Dermatologic Disorders
SectionEditor:L.Michael Posey
105. Dermatologic Drug Reactionsand Common Skin Conditions.. 1661Rebecca M. Law and David T.S. Law
& The complete chapter,learningobjectives,and other resourcescan be found at www.pharmacotherapyonline.com.
1 06. Acne V ulgaris. . . . .. . . . . . . . .. . . . . . . . . . . . . . . . 1673
Debra J. Sibbald
107. Psoriasis 1693
Rebecca M. Law and Wayne P. Gul/iver
108. Atopic Dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . . 1707
Rebecca M. Law and Po Gin Kwa
SECTION 15
Hematologic Disorders
Section Editor: Gory C. Yee
109. Anemias 1717
KristenCook,BeataA. lneck,and William1. Lyons
11O.Coagulation Disorders . . . . . . . . . . . . . . . . . . . . . . 1741Betsy Bickert Poon, Char Witmer, and Jane Pruemer
111. SickleCell Disease . . . . . . . . . . . . . . . . . . . . . . . . .. 1765
C. Y. Jennifer Chan and Reginald Moore
112. Drug-Induced HematologicDisorders. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1781
Christine N. Hansen and Amy F. Rosenberg
SECTION16
Infectious Diseases
SectionEditor:Joseph T.DiPiro
113. Laboratory Tests to Direct AtimicrobialPharmacotherapy. . . . . . . . . . . . . . . . . . . . . . . . . . . 1797
Michael J.Rybak, Jeffrey R. Aeschlimann,
and Kerry 1. Laplante
114. Antimicrobial Regimen Selection. . . . . . . . . . . . . 1813
David S. Burgess
115. Central Nervous System Infections. . . . . . . . . . . . 1825
Isaac F. Mitropoulos, Elizabeth D. Hermsen,
and John C. Rotschafer
116. LowerRespiratory Tract Infections . . . . . . . . . .. 1845
Martha G. Blackford, Mark 1. Glover,and Michael D. Reed
117. Upper Respiratory Tract Infections . . . . . . . . . .. 1867Christopher Frei, Bradi Frei, and George Zhanel
118. Influenza. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1881
Jessica C. N)oku and Elizabeth D. Hermsen
119. Skin and Soft- Tissue Infections. . . . . . . . . . . . . .. 1893
Douglas N. Fish, Susan 1. Pendland,
and Larry H. Danziger
120. Infective Endocarditis. . . . . . . . . . . . . . . . . . . . . . . 1913
Angie Veverka and Michael A. Crouch
121. Tuberculosis. .. . . . . . . . . . . . . . . . . . . . . .. . . . . . . 1931
CharlesA. Peloquinand Rocsanna Namdar
122. Gastrointestinal Infections and
Enterotoxigenic Poisonings . . . . . . . . . . . . . . . . . . 1951
Steven Martin and RoseJung
123. Intraabdominal Infections . . . . . . . . . . . . . . . . . . . 1969
Joseph T. DiPiro and Thomas R. Howdieshell
124. Parasitic Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . 1981
J. V. Anandan
125. Urinary Tract Infections and Prostatitis . . . . . . . 1995
Elizabeth A. Coyleand Randall A. Prince
126. Sexually Transmitted Diseases. . . . . . . . . . . . . . . . 2011
Leroy C. Knodel
127. Bone and Joint Infections . 2029
Edward P. Armstrong and Allan D. Friedman
128. SevereSepsis and Septic Shock. . . . . . . . . . . . . . . 2041S. Lena Kang-Birken and Karla Killgore-Smith
129. Superficial Fungal Infections . . . . . . . . . . . . . . . . . 2055Thomas E. R. Brown, Linda D. Dresser, andThomas W. F. Chin
130. Invasive Fungal Infections . . . . . . . . . . . . . . . . . . . 2073
Peggy 1. Carver
131. Infections in ImmunocompromisedPatients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2105
Douglas N. Fish
132. Antimicrobial Prophylaxis in Surgery . . . . . . . . . 2131Salmaan Kan)i
133. Vaccines, Toxoids, and Other
Immunobiologics. . . . . . . . . . . . . . . . . . . . . . . . . . . 2147MaryS.Hayney
134. Human Immunodeficiency Virus Infection . . . . 2169Peter 1. Anderson, Thomas N. Kakuda,
and Courtney V.Fletcher
SECTION17
Oncologic Disorders
Sedion Editor:GoryC. Yee
135. Cancer Treatment and Chemotherapy .2191Patrick J. Medina and Stacy S. Shord
136. Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2229
Laura Boehnke Michaud, Chad M. Barnett,and Francisco J. Esteva
137. Lung Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2271DeborahA. Friezeand ValR.Adams
& The complete chapter,learningobjectives,and other resourcescan be found at www.pharmacotherapyonline.com.
138. Colorectal Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . 2287
Lisa E. Davis, Weijing Sun, and PatrickJ. Medina
139. Prostate Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2319
LeAnn B. Norris and Jill M. Ko/esar
140. Lymphomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2333
A/exandreChanand GaryC. Yee
141. Ovarian Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2361
JudithA. SmithandJudithK. Wolf
142. Acute Leukemias . . . . . . . . . . . . . . . . . . . . . . . . . . . 2377
Betsy Bickert Poon and Dianne M. Brundage
143. Chronic Leukemias . . . . . . . . . 2401
Christopher A. Fause/ and Patrick ]. Kie/
144. Multiple Myeloma . . . . . . . . . . . . . . . . . . . . . . . . . . 2417
Timothy R. McGuire and CaseyB. Williams
145. Myelodysplastic Syndromes .. . . . . . . . . . . . . . . 2431
Julianna A. Burzynski and Tracey Wa/sh-Choco/aad
146. Renal Cell Carcinoma" . . . . . . . . . . . . . . . . . . . . 2433Christine M. Wa/ko, Ninh M. La-Beck.and Mark D. Wa/sh
147. Melanoma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2435
Cindy 1. O'Bryant and Jamie c. Poust
148. Hematopoietic Stem CellTransplantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2455Janelle B. Perkins and Gary C. Yee
Nutntional Oisorders
Section Editor:Gary R. Matzke
149. Assessment ofNutrition Status,and Nutrition Requirements . . . . . . . . . . . . . . . . . 2473Katherine Hammond Chessman
and Vanessa]. Kumpf
150. Medication Administration Considerations
with Specialized Nutrition Support . . . . . . . . . . . 2493Ro/and N. Dickerson and Gordon S. Sacks
151. Parenteral Nutrition . . . . . . . . . . . . . . . . . . . . . . . . 2505ToddW.Mattoxand CatherineM. Crill
J52. Enteral Nutrition . . . . . . . . . . . . . . . . . . . . . . . . . . . 2527
Vanessa ]. Kumpf and Katherine Hammond Chessman
153. Nutritional Considerations in MajorOrgan Failure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2545
Brian M. Hodges and Mark DeLegge
154. Obesity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2567Judy T. Chen, Amy Heck Sheehan,JackA. Yanovski, and Karim Anton Calis
Glossary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2585
Index 2613
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