addressing the unmet need in nonalcoholic steatohepatitis
Post on 31-Dec-2015
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Addressing the Unmet Need in Nonalcoholic Steatohepatitis
NAFLDHepatic Manifestation of Metabolic
Syndromea
NAFLD (cont)Hepatic Manifestation of Metabolic
Syndromea
NAFLD/NASH Closely Associated With Visceral Obesity, Insulin
Resistance
AASLDCurrent Therapeutic Recommendations for
NAFLD/NASH
Pioglitazone vs PlaceboSignificant Improvement of Histologic Features
and Insulin Sensitivity
11β-HSD1 Inhibitor RO5093151 Inhibits Adipocyte Differentiation
Galectin-3 Binding Drug GR-MD-02 Inhibits Hepatic Injury in Mouse
Model
Obeticholic Acid Improves Insulin Sensitivity and Markers of Liver
Injury
Selective Serotonin 2C Receptor Agonists Aid Weight Loss
Phentermine and Topiramate ER, an STR, Improves Weight Loss
Incretin Mimetics and Analogs Aid Maintenance of Glucose Balance
Abbreviations
References
References (cont)
References (cont)
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