ahs13 tim gerstmar - it ain't your great-grandparents world: environmental...

“Everybody needs beauty as well as bread, places to play and pray in, where nature may

heal and give strength to body and soul.” John Muir

BACON“Everybody needs beauty as well as bread,

places to play and pray in, where nature may heal and give strength to body and soul.”

NOT John Muir

It Ain't Your Great-Great Grandparents

World: Environmental

Toxicity and Health

Dr. Tim Gerstmar

“I think that people who use cleanses may have had rough anal periods (see Freud, Sigmund)...Cleanses and...colonics have about as much medical merit...as the acts of penance done by monks who’d walk across Europe and hit themselves on the back to purge themselves of the plague.” --Michael Gershon, MD

OVERVIEW

1. Toxicity - what is it? Is it real?

2. Evolutionary context

3. Health effects – example: thyroid

4. Vulnerability

5. Detox – what is it? How to do it

6. Q&A – Fingers crossed

What is Toxicity?

Toxin – substance that interferes with normal metabolic function

Metabolic toxicity

Endotoxemia

Xenotoxicity

Evolutionary discordance

Evolutionary discordance

Evolutionary exposure

Evolutionary exposure

Evolutionary exposure

Evolutionary exposure

Evolutionary exposure

Evolutionary exposure

Current exposure

China

China

Huai river - 1973-2006

Cancer-related deaths >2x

Liver cancer >5x

“The data confirms a geographical overlap in the increased cancer death rate and water pollution…

and a temporal lag - a high occurrence of cancer following a surge in pollution - for about a decade...”

Ruled out other known risk factors – smoking, diet, hepatitis B

Current exposure

Body Burden Studies

•9 adults

•Tested for 214 chemicals; Found 171

•Average 91 per person with 58 carcinogens

First Round - 2003

Body Burden Studies

•55 adults

•Tested for 528 chemicals; Found 432

•Average 156 per person with 23 carcinogens

Second Round - 2005

Body Burden Studies

•10 newborns•Found 287 chemicals

•180 cause cancer in humans or animals•217 are toxic to the brain and nervous system•208 cause birth defects or abnormal development in animals

Newborns- 2004

Scorecard.org – Zip 30303

In 2002, Fulton county ranked among the dirtiest/worst 10% of all counties in the U.S. in terms of air releases of recognized carcinogens.

1 FORD ATLANTA ASSEMBLY PLANT HAPEVILLE 788,037 lbs

2 OWENS CORNING FAIRBURN 455,505

3 PPG ARCHITECTURAL FINISHES EAST POINT 139,424

4 KRAFT FOODS ATLANTA PLANT ATLANTA 43,579

5 POREX TECHS FAIRBURN 41,228

Scorecard.org – Zip 30303

1 AMMONIA 428,389 lbs

2 XYLENE (MIXED ISOMERS) 248,797

3 GLYCOL ETHERS 168,253

4 N-BUTYL ALCOHOL 152,056

5 METHYL ISOBUTYL KETONE 129,791

6 TOLUENE 103,007

7 FORMALDEHYDE 100,389

8 1,2,4-TRIMETHYLBENZENE 68,175

9 METHYL ETHYL KETONE 64,175

10 ETHYLBENZENE 53,326

Types of Toxic Exposures

1. Acute

2. Chronic – single agent, mixed agents

3. Contributing

Acute Exposure

Chronic exposure

Chronic exposure

65yo male

Peripheral neuropathy (of trunk & arms)

Chloracne

Insulin-dependent diabetes

BMI 33

Fasting glucose 306

Chronic exposure

65yo male 67yo malePeripheral neuropathy (of trunk & arms)

Chloracne

Insulin-dependent diabetes

BMI 33 27 (-40lbs)

Fasting glucose 306 95

Chronic exposure

Contributing exposure

What do toxins do?

-Endocrine disruption

-Carcinogens or growth disruptors

-Immune disruptors

-Neurotoxins

-Mitochondrial poisons

Health risks

Hormone disruptionThyroid Trouble

1. Nutrient deficiencies

2. Autoimmunity (~50% have other AI)

3. Neurological & other hormonal dysfunctions

4. Toxicity

Thyroid – the parts

Thyroid – how it's supposed to work

Thyroid – how it's supposed to work

Thyroid – how it's supposed to work

Thyroid – how it's supposed to work

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Thyroid & Environmental toxicity

Is Xenotoxicity a concern?

Spectrum of Sensitivity

Multiple “Cast Iron” Chemical Sensitivity

Genetics of Detox

Genetics of Detox

Genetics of Detox

Functional Detox Impairment

Understanding Detox

Process NOT tools

What is detoxification?

Inactivation of a toxic substance

1. Mobilization

2. Inactivation

3. Excretion

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

Mobilization

Inactivation

EnergyNutrients (Cofactors)

Excretion

Excretion

DESIGN FLAW!!!Enterohepatic recirculation

DESIGN FLAW

DESIGN FLAW=

EVOLUTIONARYDISCORDANCE

Do we need to augment detox?

Acutely – “Detox or die”

Chronic - Detox to resolve health problems

Contributing – evolutionary mismatch

Augment detox?

Rational Detoxification

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

What goes in

Reduce Exposure

Testing your water

Testing your water

Reduce ExposureCosmetics

Household chemicals Lawn Chemicals

Buildings

Biotransformation

Biotransformation / Detox

1. Energy2. Nutrients / Cofactors

Herbs & Phytochemicals

Supplemental Precursors

Supplemental glutathione

Juicing?

What comes out

Making poop

Avoid constipation

DESIGN FLAW!!!Enterohepatic recirculation

Increasing bile excretion

Enemas and Colonics

Using the skin

Putting it together

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

DetoxificationWhat goes in

What comes out

The body

DetoxificationWhat goes in

What comes out

The bodyBody burden = what

stays insideBiotransformation

(Detox)

Putting it together

1. Limit exposure (reduce toxicity in)

Putting it together

1. Limit exposure (reduce toxicity in)

2. Nutrient dense diet w/ protein (detox)

3. Drink water (detox)

4. Supplemental nutrients & herbs (detox)

Putting it together

1. Limit exposure (reduce toxicity in)

2. Nutrient dense diet w/ protein (detox)

3. Drink water (detox)

4. Supplemental nutrients & herbs (detox)

5. Pee & Poop regularly (excretion)

6. Defeat enterohepatic recirculation (excretion)

“Aggressive” detox

1. Genetic testing

1. Genetic testing2. Functional testing

1. Genetic testing2. Functional testing3. Direct measurement of various toxins

Toxicity hurts

Sensible detox can help

You can't hide!

Rational Detox

“I think that people who dismiss cleanses & environmental toxicity without actually researching or understanding the topic may have had rough anal periods (see Freud, Sigmund)...Rationally used cleanses have medical merit, and those who deny it are still living in the medical dark ages...”

--Tim Gerstmar, ND

Dr. Tim Gerstmar

www.aspirenaturalhealth.comwww.facebook.com/AspireNaturalHealth@DrTimGerstmarND