cancer mitosis gone wild! tan = sexy, and risking death

Cancer

Mitosis Gone Wild!Tan = Sexy, and

Risking Death

Tan = Sexy?

Tan = Sexy?

Naomi

Tumor

Means “swelling” Come to refer to abnormal

growth of tissue.Two types of tumors:

BenignMalignant

Benign

Means “not life threatening”Do not invade other tissues.Do not break apart and spread to

other parts of the body (metastasize)

Can grow really big and become a serious health problem, possibly life threatening.

Premalignant

Benign tumors are at greater risk for turning into “cancer” than other tissue.

If they start to “degenerate” then they are called premalignant.

Malignant

Cells dedifferentiate – lose specializations like cilia and axons.

Metastasize Break away from

tumor move through blood stream to other parts of the body

Divide and grow into another cancerous tumor.

Cancer

Testicle Cells in you Lungs!Breast Tissue in your Brain!

Contact Inhibition

Cell to cell contact usually stops cell division, not with cancerous cells.

Oncogenes

Genes control cell division – produce checkpoint proteins.

Mutations can cause cells to go through mitosis too often = tumor.

Growth Factor

Tumor cells either are missing growth factor inhibition or make their own growth factor proteins.

Carcinogens

PhysicalUVHeat

ChemicalBind with DNA

BiologicalViruses