cheminform abstract: synthesis of chaetomellic anhydride a, a potent inhibitor of ras protein...

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www.cheminform.wiley-vch.de

Other bioactive productsU 1300 Synthesis of Chaetomellic Anhydride A, a Potent Inhibitor of RAS Protein Farne-

syltransferase. — A short and high-yielding route to chaetomellic anhydride A (IV) is elaborated using the palladium-catalyzed carboxylation of triflate (II) with sodium for-mate as key step. — (YOSHIMITSU*, T.; ARANO, Y.; KAJI, T.; INO, T.; NAGAOKA, H.; TANAKA, T.; Heterocycles 77 (2009) 1, 179-186; Grad. Sch. Pharm. Sci., Osaka Univ., Suita, Osaka 565, Japan; Eng.) — R. Staver

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ChemInform 2009, 40, issue 22 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

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