clinical features and complication of diabetes 3
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CLINICAL FEATURES AND COMPLICATION OF
DIABETES
e.saranya
Polydipsia
Polyuria
Polyphagia
SIGNS AND SYMPTOMS
TYPE 1 DIABETES TYPE 2 DIABETES
AGE AT ONSET <40 YRS >50 YRS
BODY.WT NORMAL OBESE
KETONURIA PRESENT ABSENT
AUTOANTIBODIES PRESENT ABSENT
FAMILY.HIST OFDIABETES
NO 25% OF CASES
ASS WITH FAM.HIST
DIABETIC RETINOPATHY
DIABETIC NEPHROPATHY
DIABETIC NEUROPATHY
CARDIOVASCULAR DISEASE
FOOT PROBLEM
COMPLICATION
DIABETIC KETOACIDOSIS
HYPERGLYCEMIC HYPEROSMOLAR
NONKETOTIC COMA
ACUTE GLYCAEMIC COMPLICATION
Absolute insulin deficiency
Release of fatty acids from fat cells
Hepatic ketogenesis
symptoms
Diabetes ketoacidosis
Signs {dka}
DehydrationHypotensionKussmaul breathingDrowsiness{coma}
hhnkc Weakness
Inc.thirst
Lethargy
confusion
occurs as a result of treatment with insulin
hypoglycaemia
autonomic• Sweating• Hunger• anxiety
neuroglcopenic• Drowsiness• unable to concentrate• incoordination
hypoglycaemia
Diabetic retinopathy and macular oedema
Microaneurysm
Inc.vascular permeability
proliferation of new vessels and fibrous tissue
Contraction of fibrous tissue and haemorrage
Blurred vision
floaters
blindness
symptoms
Microaneurysm
Macular oedema
CottonWoolspot
Neovascularisation
signs
symptoms fatigue
Excess froth of urine
Swelling of legs
Periorbital oedema
UnintentionalWt.gain
Diabetic nepropathy
Persistent protein in urine
microalbuminuria {30-300mg/day}
signs
DIABETIC NEUROPATHY
NUMBNESS MUSCLE WEAKNESS
CONSTIPATIONPOSTURAL
HYPOTENSION
URINARYINCONTINENCE
Atherosclerosis
Cardiomyopathy
stroke
CARDIOVASCULAR COMPLICATION
CAUSE:
TRAUMA INFECTION
RESULTS IN:
ULCER SEPSIS GANGRENE
DIABETIC FOOT
Toxemia of pregnancy
Birth defects
Macrosomia
Noenatal hypoglycaemia
Pregnancy related complication
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