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DAFTAR RIWAYAT HIDUP
1. Nama Lengkap : Prof. Dr. Edy Meiyanto, M.Si., Apt.
2. Pekerjaan : Dosen Fakultas Farmasi Universitas Gadjah Mada
3. NIP : 196205021989031006
4. NIDN : 0002056206
5. Jenis kelamin : Pria
6. Tempat dan tanggal lahir: Solo, 2 Mei 1962
7. Alamat Rumah : Jl. Arwana No. 12 Perum Minomartani
Yogyakarta
Telp. (0274) 883621
8. E-mail : meiyan_e@ugm.ac.id; edy_meiyanto@ugm.ac.id;
edy.meiyanto@gmail.com; meiyan_e@yahoo.com
9. Google Scholar :
http://scholar.google.com/citations?user=C1DwiokAAAAJ&hl=en
10. Research Gate :
https://www.researchgate.net/researcher/54386761_E_Meiyanto
11. Pangkat/Golongan : Pembina Utama Madya/IVd
12. Jabatan : Profesor/Guru Besar
13. Alamat kantor : Fakultas Farmasi UGM
Sekip Utara Yogyakarta, 55281, telp/fax: 0274-543120
2
10. Pendidikan
Jenjang
Pendidikan
Tempat Tahun
selesai
Gelar Bidang studi
S-1 Fak. Farmasi UGM 1986 Drs. Ilmu farmasi
Profesi Fak. Farmasi UGM 1987 Apoteker
S-2 Fak. Farmasi UGM 1995 M.Si. Ilmu farmasi
S-3 NAIST – Japan 2001 Ph.D. Molecular
oncology
Judul Disertasi: “Development of labeling method for macro/microarrays and its
application for gene expression profiling in osteoclastogenesis”
11. Riwayat Kepangkatan
No Golongan Pangkat TMT Jabatan
1 III/a Calon Pegawai Negeri
Sipil
01-03-1989
2 III/a Penata Muda 01-12-1990 Aisten ahli
madya
3 III/b Penata Muda Tk I 01-04-1996 Asisten ahli
4 III/c Penata 01-04-1998 Lektor muda
5 III/d Penata Tk I 01-04-2003 Lektor
6 IV/a Pembina 01-04-2007 Lektor kepala
7 IV/b Pembina madya 01-04-2009 Lektor kepala
8 IV/b Pembina madya 01-09-2010 Guru
besar/profesor
9 IV/c Pembina Utama Muda 01-09-2011 Profesor
10 IV/d Pembina Utama Madya
3
12. Riwayat Jabatan dalam Pekerjaan Dosen
Jabatan Unit kerja Tahun
Pengelola Magister farmasi klinik Fak. Farmasi UGM 2001/2004
Sekretaris Bagian Kimia Farmasi Fak. Farmasi UGM 2003-2005
Kepala Laboratorium Biokimia PS
Bioteknologi
PS Bioteknologi UGM 2005
Wakil dekan bidang Kemahasiswaan,
Alumni, Riset dan Kerjasama
Fak. Farmasi UGM 2005-2008
Wakil Dekan bidang kemahasiswaan,
alumni, kerjasama, dan pengembangan
Fak. Farmasi UGM 2008-2012
13. Pengalaman kerja dalam penelitian (sejak 2002)
Judul penelitian Sumber dana Periode Kerja
Efek antiprolliferatif dan metastasis tulang
PGV-0 pada sel kanker payudara T47D
RUT 2002/2004
Efek antikarsinogenik ekstrak etanol daun
sambung nyawa pada kanker payudara
Hibah
Bersaing XI
2003-2004
Isolasi dan Penentuan Struktur Zat Bioaktif
Ekstrak Kulit Batang Cangkring (Erythrina
fusca L.) dan Uji Sitotoksiknya
Que Project 2003/2004
Pelacakan senyawa antikanker daun
tumbuhan Cangkring (Erythrina fusca)
HB XIII-Dikti 2005-2006
Efek antikarsinogenesis jinten hitam
terhadap kanker payudara yang diinduksi
DMBA
Hibah Pekerti 2006-2007
Sensitisasi agen kemoterapi oleh ekstrak
pinang terhadap sel kanker payudara
HB XIV 2007-2008
The cytotoxic activity and apoptosis
induction of 8-hydroxyisocapnolactone-
2΄,3΄-diol with and without doxorubicin on
MCF-7 and T47D breast cancer cell lines
Hibah
Fakultas
2008
Co-Chemotherapeutical potential of citrus
flavonoids for breast cancer
Hibah Pasca-
DIKTI
2009-2010
Exploration of anticancer mechanism of
curcumin analogues and metabolites of
Indonesian herbs
Kerjasma
NAIST-Japan
2008-2010
4
Immunomodulatory activity of Citrus
reticulata’s pell ethanolic extract through
modulation of cell proliferation and
expression of interleukin-3 (IL-3) and
cyclooxygenase-2 (COX-2) on RAW 264.7
macrophage cell line
Hibah UGM 2009
Studi Potensi Antikanker Keladi Tikus
(Thyphonium Flagelliformae (Lodd.) Blume
Dan Efek Immunomodulator: Kajian
Terhadap Mekanisme Aksi Dan Sebagai
Agen Ko-Kemoterapi Pada Kanker
Payudara
Hibah
Strategis
Nasional
DIKTI
2010
Isolat Eurycomanon Akar Pasak Bumi
(Eurycoma Longofolia Jack) Sebagai Ko-
Kemoterapi Doxorubicin Terhadap Sel
Kanker Payudara Mcf-7 Dan T47d Serta Uji
Toksisitasnya Pada Tikus Galur SD
Hibah Pekerti 2011
Analisis Target Molekuler Pada Kombinasi
8-Hidroksiisokapnolakton-2',3'-Diol
Dengan Agen Kemoterapi Cisplatin
Terhadap Protein Nfkb Dan Cox-2 Dan
Pengaruhnya Terhadap Siklus Sel Pada Sel
Kanker Kolon
Hibah
IMHERE
Fakultas
Farmasi UGM
2012
Development of Specific Molecular-
Targeted Agents to Increase Sensitivity of
resistance Breast Cancer Cells to
Chemoterapeutic Agent
Hibah
Kerjasama
Luar Negeri
Dikti
2012-2014
Produksi Protein Farmasetik Recombinant
Human Erythropoietin (Rhepo) Dengan
Modifikasi Pola Glikosilasi Pada Sel
Hek293t
RISTEK-
SINAS
Penelitian
Kerjasama
dengan LIPI
2012-2014
Potensi dan Molecular Targets Senyawa
Aktif Ekstrak Etanolik Kayu Secang
(Caesalpinia sappan L) sebagai Agen
Chemosensitizer pada Kanker Payudara :
Pengembangan Fitofarmaka Secang
Hibah
Kerjasama
Institusi
2013
5
Sebagai Agen Kemopreventif
Komplementer untuk Terapi Kanker
Payudara yang Lebih Efektif (Kolaborasi
antara Cancer Chemoprevention Research
Center dengan Balai Besar Penelitian dan
Pengembangan Tanaman Obat dan Obat
Tradisional)
Disain Formula Obat Kanker Berbasis
Herbal Dengan Pendekatan Kombinasi
Terarah Untuk Kanker Payudara
Metastasis
Insentif SiNAS
Ristek
2014
Pengembangan Teknologi dan Aplikasi
Boron Neutron Capture Cancer Therapy
dengan Compact Neutron Generator
Insentif SiNAS
Ristek
(Konsorsium
dengan
BATAN)
2014-2015
Validasi Metode Uji Efek Genotoksik Untuk
Produk Herbal Dan Bahan Tambahan
Makanan
PUPT DIKTI 2015
Menakar Efek Bifasik Genistein, Kurkumin
dan Analognya untuk Dikembangkan
sebagai Agen Antikanker dan Sediaan
Estrogenik
HIKOM DIKTI 2016
Validasi Metode Uji Efek Genotoksik Untuk
Produk Herbal Dan Bahan Tambahan
Makanan (Lanjutan)
PUPT DIKTI 2016
Pengembangan Teknologi dan Aplikasi
Boron Neutron Capture Cancer Therapy
dengan Compact Neutron Generator :
Mengembangkan Senyawa Boron Berbasis
Analog Kurkumin dan Sistem Ujinya
Hibah
INSINAS
kerjasama
dengan
BATAN
2016
Pengembangan Produksi Bahan Baku Obat
Berbasis Biosimilar Recombinant Human
Erythropoietin : Uji Aktivitas Biologi In
Vitro dan In Vivo serta Uji Toksisitas Akut
Produk Biosimilar Recombinant Human
Erythropoietin
Hibah PPTI
Kerjasama
dengan
Biofarma dan
LIPI (Tahun
Pertama/RIST
2016
6
EK DIKTI)
Menakar Efek Bifasik Genistein, Kurkumin
dan Analognya untuk Dikembangkan
sebagai Agen Antikanker dan Sediaan
Estrogenik
Hibah
Kompetensi
(Tahun
Kedua)
2017
Manufaktur dan Standardisasi Komponen
Kolimator dan Obat Berbasis Boron
Neutron Capture Cancer Therapy (BNCT)
Program
Insentif
Inovasi
Industri (PIII)
Kerjasama
dengan
BATAN
2017
Pengembangan Produksi Bahan Baku Obat
Berbasis Biosimiliar Recombinant Human
Erythropoietin
Sub Judul: Uji Aktivitas Biologi In Vivo
serta Uji Toksisitas Akut Produk Biosimilar
Recombinant Human Erythropoietin
PPTI
Kerjasama
dengan
Biofarma dan
LIPI (Tahun
Kedua)
2017
Pengembangan Metode Analisis Reactive
Oxygen Spesies (Ros) Menggunakan 2’,7’-
Dichlorofluorescin Diacetate (Dcfda) pada
MCF-7/HER2 dan NIH3T3
Hibah
Pengembanga
n Penelitian
Laboratorium
dengan Lab.
Kimia Analisis
DKF
2017
Efek Kombinasi Hesperetin dengan
Doksorubisin terhadap Proliferasi dan
Metastasis pada Sel Kanker 4T1
Hibah
Penelitian
Penunjang
Thesis
2017
Pengembangan Agen Anti Kanker
Payudara dari Daun Katuk Hutan Papua:
Kajian Efek Anti Proliferatik dan Anti
Metastatik
Hibah Pekerti 2017
Isolasi Senyawa Aktif dari Daun
Micromelum minutum dan Penelusuran
Aktivitas Penghambatan pada Sel Kanker
Payudara MCF-7
PUPT DIKTI 2017
7
14. Aktivitas mengajar
a. Metodologi Penelitian (S-1 dan S-2)
b. Biologi Molekular (S-1, S-2, dan S-3)
c. Biokimia (S-1)
d. Karsinogenesis molecular (S-2 dan S-3)
e. Analisis Klinik/biomedik (S-1 dan S-2)
15. Afiliasi organisasi
a. Ikatan Sarjana Farmasi Indonesia (anggota)
b. Indonesian Biochemistry and Molecular Biology Society (member)
c. Perhimpunan Peneliti Bahan Obat Alami (PERHIPBA) Indonesia (Pengurus
pusat - 2009)
d. Indonesian Society for Cancer Chemoprevention (Ketua, 2017-2020)
e. Ketua Cancer Chemoprevention Research Center (CCRC) Fakultas Farmasi
UGM (2004-Sekarang)
16. Tema riset utama
Pengembangan obat untuk antikanker dan chemoprevention
(URL: http://ccrc.farmasi.ugm.ac.id)
17. Daftar Publikasi (terseleksi sejak tahun 2001)
2001
Meiyanto, E., Hoshijima M., Ogawa T., Ishida N., and Takeya T., 2001, Osteoclast
Differentiation Factor Modulates Cell Cycle Machinery and Causes a Delay in S Phase
Progression in RAW264 cells, Biochem Biophys Res Commun, 282: 278-283.
Meiyanto, E., Jun-ichi Mineno, Ishida N and Takeya T., 2001, Application of
fluorescently labeled poly (dU) for gene expression profiling on cDNA microarrays,
BioTechniques, 31 (2) : 406-413.
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2002
Da’i, M., Meiyanto, E., and Supardjan, A.M., 2002, Antiproliferative effect of
curcumin on Raji cell line, Pharmacon, 3(2): 40-45.
2003
Meiyanto, E., Supardjan A.M., and Da’i, M., 2003, Antiproliferative effect of PGV-0 (a
curcumin analogue) against HeLa cells, Gama Sains, 5 (3): 200-206.
Sugiyanto, Sudarto, B., Meiyanto, E., and Nugroho, A.E., and Jenie AU., 2003, The
anticarcinogenicity of plants compounds, Indonesian Journal of Pharmacy, 14(3):
132-141.
Meiyanto, E., Sismindari, Chandra, L., and Moordiani, 2003, Antiproliferative effect
of the bark and leaves of Erythrina fusca Lour against HeLa Cells, Indonesian Journal
of Pharmacy, 14(3): 124-131.
2004
Meiyanto, E., Sismindari, dan Triastuti, A., 2004, Efek antiproliferatif ekstrak etanol
kulit batang Cangkring (Erythrina fusca Lour) terhadap sel Myeloma, J. Ilmiah
farmasi UII.
Murwanti, R., Meiyanto, E, Kristina, S. A., 2004, Anticarcinogenic effect of Ethanolic
extract of Curcuma zedoaria Rosc. on the growth of Lung tumor induced by
benzo(a)pirene, Maalah Farmasi Indonesia, 15(1): 156-161.
Da’i, M., Meiyanto, E., and Supardjan, A.M., 2004, Antiproliferative effect of
Pentagamavunon-0 on Myeloma cells, Sains kesehatan, 17(1):
2005
Meiyanto, E., and Septistyani, EP, 2005, Efek antiproliferatif dan apoptosis fraksi
fenolik ekstrak etanolik daun Gynura procumbens terhadap sel HeLa, Artocarpus,
(5) 2: 74-80.
9
Maryati, Meiyanto, E., and Riyanto, S., 2005, Uji Sitotoksik dan isolasi flavonoid dari
fraksi etil asetat daun Gynura procumbens (Lour) Merr, Pharmacon, Vol 6 No. 2, 46-
50.
2006
Meiyanto, E., Melannisa, R., Da’i, M, 2006, PGV-1 Menurunkan Ekspresi Faktor
Angigenesis (VEGF dan COX-2) Pada Pertumbuhan Sel T47D Terinduksi Estrogen,
Majalah Farmasi Indonesia, 17 (1):01-06.
Meiyanto, E., Supardjan, Da’i, M, Agustina, D, 2006, Efek Antiproliferatif
Pentagamavunon-0 terhadapSel Kanker Payudara T47D, Jurnal Kedokteran Yarsi, 14
(1), 11-15.
Nurulita, NA., and Meiyanto, E., 2006, Efek antikanker PGV-0 terhadap sel kanker
payudara T47D yang diinduksi 17-b-estradiol melalui mekanisme apoptosis dan
penghambatan angiogenesis, Sains Kesehatan, 19, (1): 109-125.
Jenie, R.I., Meiyanto, E., dan Murwanti, R, 2006, Efek antiangiogenik ekstrak
etanolik daun sambung nyawa (Gynura procumbens (Lour.) Merr.) pada membran
korio alantois (cam) embrio ayam, Majalah Farmasi Indonesia, 17 (1): 50-55.
Meiyanto E, Melannisa R., and Dai M., 2006, Penurunan ekspresi BCl-2 berperan
dalam apoptosis sel kanker payudara T47D yang diinduksi PGV-1 dan 17-b-estradiol,
Pharmacon, vol 7, No. 2, 58-62.
2007
Meiyanto, E., 2007, Curcumin and PGV-0 suppress in vitro osteoclastogeneis and
induce apoptosis on osteoclast cells, Proceedings of the international symposium on
recent progress in curcumin research 11-12 september 2006, Yogyakarta-Indonesia,
ISBN: 978-979-3485-55-3: 269-276.
Meiyanto, E., Supardjan, Da’i, M, Agustina, D, 2007, Pentagamavunon-0 induces
Apoptosis on T47D breast cancer cell line through Caspase-3 activation, Jurnal
Kedokteran Yarsi, 15(2): 075-079.
10
Dai M., Supardjan AM., Meiyanto E., and Jenie UA., 2007, Geometrics isomers and
cytotoxic effect on T47D cells of curcumin analogues PGV-0 and PGV-1, Majalah
Farmasi Indonesia, 18 (1):
Dai M., Supardjan AM., Meiyanto E., Jenie UA., and Masashi K., 2007, Potensi
proliferatif analog kurkumin: pentagamavunon terhadap sel kanker payudara T47D,
Artocarpus, 7(1) : 14-20.
Muhammad Dai, Anis Fiveri, and Meiyanto E., 2007, Efek Sitotoksik Ekstrak
Tanaman Keladi Tikus, Jurnal Farmasi Indonesia, 3(4): 163-167.
Dai M., Supardjan AM., Meiyanto E., Jenie UA., and Masashi K., 2007, Curcumin
Induce Apoptosis On Breast Cancer Cell line with Wild Type and Mutant p53 Status ,
Proceeding on International conference on traditional medicine and medicinal plants,
8-9 September.
Jenie, R.I., and Meiyanto, E., 2007, Aplikasi ko-kemoterapi ekstrak etanolik daun
Gynura procumbens (Lour.) Merr. pada sel kanker payudara, Majalah Farmasi
Indonesia, 18 (2): 81-87.
Sri Susiloati, Meiyanto E., and Sugiyanto, 2007, Efek ekstrak etanolik daun Gynura
procumbens (Lour) Merr terhadap proliferasi sel kanker payudara tikus yang
diinduksi 7,12-dimetilbenz(a)antrazen (DMBA), Majalah Obat Tradisional, 11(40):
19-24.
Meiyanto E., Rahmi, F., dan Riyanto, S, 2007, Efek Sitotoksik Fraksi Semipolar
Ekstrak Metanolik Kulit Batang Cangkring (Erythrina fusca Lour) Terhadap Sel HeLa,
Majalah Obat Tradisional, 11(41): 1-11.
Meiyanto E., Susilowati s., Tasminatun S, Murwanti R., dan Sugiyanto, 2007, Efek
kemopreventif ekstrak etanolik daun Gynura procumbens (Lour.) Merr. pada
karsinogenesis kanker payudara tikus, MFI, 18(3): 154-161.
Meiyanto E., Susilowati s., Tasminatun S, Murwanti R., dan Sugiyanto, 2007,
Penghambatan karsinogenesis kanker payudara tikus terinduksi DMBA pada fase
post inisiasi oleh ekstrak etanolik daun Gynura procumbens (Lour.) Merr., MFI,
18(4): 169-175.
11
Setyowati Prawita E, Sudarsono, Rahmat R., Kardono B., 2007, Jenie Anggara U., dan
Meiyanto E., Isolasi Senyawa Sitotoksik Spons Kaliapsis, Majalah Farmasi Indonesia,
18 (4) : 183-189.
Dai M., Jenie UA, Supardjan AM, Kawaichi M, and Meiyanto E., 2007, T47D cells
arrested at G2M and Hyperploidy formation induced by a curcumin analogue, PGV-1,
Indon. J. Biotechnol., 12 (2): 1005-1012.
2008
Meiyanto E, RA Susidarti, S Handayani, and F Rahmi, 2008, Ekstrak etanolik biji
pinang (Areca catechu L.) mampu menghambat proliferasi dan memacu apoptosis
sel MCF-7, MFI, 19(1): 12-19.
Meiyanto E., Sri Handayani, RA Susidarti, and Riris I Jenie, 2008, Areca (Areca
catechu L.) Seeds Ethanolic extract and its chloroform fraction increase apoptotic
effect of doxorubicin on human colon cancer cells, j. Bahan Alam Ind., 6(5): 169-175.
Widaryanti B., Meiyanto E., Dai M., and Kawaichi M., 2008, PGV-1 is a potent anti
mitotic agent, Indon. J. Pharm, 19(3): 145-150.
Meiyanto E., Sri Handayani, dan Riris Istighfari Jenie, 2008, Ekstrak etanolik kacang
panjang (Vigna sinensis (L) Savi ex Hassk) meningkatkan proliferasi sel epitel
payudara dan perkembangan kelenjar payudara melalui peningkatan ekspresi
reseptor estrogen, M. farm. Indon., 19(4): 191-197.
Riris Istighfari Jenie and Edy Meiyanto, 2008, Combination of Sambung Nyawa
(Gynura procumbens (Lour.) Merr.) leaves ethyl acetate fraction (SEF)-Doxorubicin
(dox) induces apoptosis in human breast cancer T47D Cells, Proceeding The
International symposium on Molecular targeted Therapy, ISBN: 978-979-95107-6-1,
Faculty of Pharmacy UGM, pp. 37-47.
Endah Puji Septisetyani, Muthi’ Ikawati, Barinta Widaryanti and Edy Meiyanto,
2008, Apoptosis mediated cytotoxicity of curcumin analogues PGV-0 and PGV-1 in
WiDr cell line, Proceeding The International symposium on Molecular targeted
Therapy, ISBN: 978-979-95107-6-1, Faculty of Pharmacy UGM, pp. 48-56.
Edison Chrisnanto, Rosa Adelina, Dyaningtyas Dewi P.P, M.N. Abdi Sahid, Diah
Setyaningtias, Riris Istighfari Jenie and Edy Meiyanto, 2008, Antiangiogenic effect
of ethanol extract of Citrus reticulata peel in the Chorio Allantoic Membrane (CAM)
12
induced by bFGF, Proceeding The International symposium on Molecular targeted
Therapy, ISBN: 978-979-95107-6-1, Faculty of Pharmacy UGM, pp. 57-66.
Sri Handayani, Edy Meiyanto and Ratna Asmah Susidarti, 2008, Areca (Areca
catechu L.) seeds ethanolic extract and its chloroform fraction induce apoptosis and
decrease COX-2 expression on WiDr cells, Proceeding The International symposium
on Molecular targeted Therapy, ISBN: 978-979-95107-6-1, Faculty of Pharmacy UGM,
pp. 67-74.
Fitria Rahmi, Edy Meiyanto and Ratna Asmah Susidarti, 2008, Apoptosis effect of
Areca catechu L. chloroform fraction on T47D cells, Proceeding The International
symposium on Molecular targeted Therapy, ISBN: 978-979-95107-6-1, Faculty of
Pharmacy UGM, pp. 75-82.
Ilyas Pratomo, Larasati, Sri Handayani, Perdana and Edy Meiyanto, 2008,
Chemoprevention effects of ethanolic extract Keprok Citrus peels (Citrus reticulata)
on epithelial mammary and liver cells of Sprague Dawley rats induced by 7,12-
Dimethylbenz-[a]anthracene, Proceeding The International symposium on Molecular
targeted Therapy, ISBN: 978-979-95107-6-1, Faculty of Pharmacy UGM, pp. 83-93.
Sarmoko, Ika Dyaning Ratri, Rifki Febriansah, A. Fauzi Romadhon, A. Perdana Adhi
Nugroho, Edy Meiyanto , Ratna Asmah Susidarti and B. S. Ari Sudarmanto, 2008,
Cytotoxic effect of ethanolic extract of Temu Kunci (Kaempferia pandurata) and
Sirihan (Piper aduncum L.) on breast cancer line, Proceeding The International
symposium on Molecular targeted Therapy, ISBN: 978-979-95107-6-1, Faculty of
Pharmacy UGM, pp. 94-102.
Muhammad Iqbal, Haryadha Agustian, Ratna Asmah Susidarti, B.S. Ari Sudarmanto
and Edy Meiyanto, 2008, Molecular docking of Coumarin and its derivative to
Protein Kinase C (PKC) and tubulin receptors : Inhibition and interaction study to
those receptors correlated with Artemisia vulgaris L. leaves extract’s cytotoxic effect
in T47D cell, Proceeding The International symposium on Molecular targeted Therapy,
ISBN: 978-979-95107-6-1, Faculty of Pharmacy UGM, pp. 103-114.
A.Asyhar, R. Febriansah, R.A. Ashari, R.A Susidarti, dan E.Meiyanto, 2008, Modulasi
Ekspresi Protein N-ras Ekstrak Etanolik Rumput Mutiara (Hedyotis corymbosa)
pada Sel Hepar Tikus Galur Sprague Dawley Terinduksi 7, 12-
Dimentilbenz[a]antrasena, Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi
Indonesia, ISBN : 978-979-95108-6-0, ISFI, pp. 127-129.
13
Adek Zamrud Adnan, E. Meiyanto, Rustini, dan Teti Dynaila, 2008, Uji Sitotoksisitas
fraksi Alkaloid Fenantroindolizidin dari Kulit Batang Ficus obscura Miq. Secara In
Vitro dengan MTT-Colorimetric Assay, Proceeding Kongres Ilmiah XVI Ikatan
Sarjana Farmasi Indonesia, ISBN : 978-979-95108-6-0, ISFI, pp. 107-110.
Anugerah B.Adina, Franciscus Feby Handoko, Indah Ikawati Setyarini, E.P.
Septisetyani, S, Riyanto, dan Edy Meiyanto, 2008, Estrak Etanolik Kulit Jeruk Nipis
(Citrus Aurantifolia (Cristm. Swingle)) Meningkatkan Sensitivitas sel MCF-7
terhadap Doxorubicin, Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi
Indonesia, ISBN : 978-979-95108-6-0, ISFI, pp. 55 – 62.
Dewi Pratiwi, Novi Hastuti, Inna Armandari, Niken Nur W, Muthi’ Ikawati, Sugeng
Riyanto, dan Edy Meiyanto, 2008, Ekstrak Etanolik Kulit Jeruk Nipis (Citrus
Aurantiifolia (Cristm.) Swingle) meningkatkan Ekspresi p53 Pada Sel Payudara
Tikus Galur Spraygue Dawley Terinduksi 7,12-Dimetilbenzen[a]antrasena,
Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, ISBN : 978-979-
95108-6-0, ISFI, pp. 100 – 106.
Diah Ayu Putri K, Perdana Adhi Nugroho, Andita Pra Darma, Muthi’ Ikawati, Sugeng
Riyanto, dan Edy Meiyanto, 2008, Potensi Kemopreventif Ekstrak Etanolik Kulit
Jeruk Keprok (Citrus reticulata) pada Sel Kanker Hepar Tikus Galur Sprague Dawley
Terinduksi 7, 12-Dimetilbenz[A]antrasena Melalui Penekanan Ekspresi c-Myc,
Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, ISBN : 978-979-
95108-6-0, ISFI, pp. 75 – 80.
Dyani P. Sukamdi, Stefani, Kartika D. Palupi, E.Meiyanto, dan R.A. Susidarti, 2008,
Potensi Antiproliferasi Ekstrak Etanolik Hedyotis corimbosa (L) Lamk Terhadap Sel
Hepar Tikus Terinduksi 7, 12-Dimetil Benz(a)antrazena, Proceeding Kongres Ilmiah
XVI Ikatan Sarjana Farmasi Indonesia, ISBN : 978-979-95108-6-0, ISFI, pp. 81 – 88.
Indri Kusharyanti, Ari Widiyantoro, Maryati dan Edy Meiyanto, 2008, Aktivitas
Sitotoksik Ekstrak Kulit Batang Pauh Kijang ( Irvingia Malayana Oliv.), Proceeding
Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, ISBN: 978-979-95108-6-0,
ISFI, pp. 36 – 41.
Maria Dwi Supriyati, Rosa Adelina, Dwi Ana Nawangsari, Muthi’ Ikawati, dan Edy
Meiyanto, 2008, Modulasi Ekspresi c-Myc Sel Epitelial Kelenjar payudara Tikus oleh
Ekstrak Etanolik Kulit Jeruk Keprok ( Citrus reticulata), Proceeding Kongres Ilmiah
XVI Ikatan Sarjana Farmasi Indonesia, ISBN: 978-979-95108-6-0, ISFI, pp. 70 – 74.
14
M Fithrul Mubarok, Dewi Arum, Ainun Wulandari, R.I Jenie., E.P. Septisetyani dan
Edy Meiyanto, 2008, Peningkatan Aktivitas Sitotoksik Doxorubisin terhadap Sel
Kanker Payudara MCF-7 menggunakan Ekstrak Etanolik Daun Awar-awar (Ficus
Septica Burm. F), Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, ,
ISBN: 978-979-95108-6-0.
Mita Ardiani, N. Puspita, Fina A.G., E. P. Septisetyani, dan E.Meiyanto, 2008, Ekstrak
Etanolik Kulit Buah Jeruk Mandarin (Citrus Reticulata) Memacu Proliferasi dan
Ekspresi Cox-2 pada Sel Kanker Kolon WiDr, Proceeding Kongres Ilmiah XVI Ikatan
Sarjana Farmasi Indonesia, , ISBN: 978-979-95108-6-0, ISFI, pp. 193 – 198.
Novi Hastuti, Dewi Pratiwi, Inna Armandari, Niken Nur W., Muthi’ Ikawati, Sugeng
Riyanto, dan Edy Meiyanto, 2008, Ekstrak Etanolik Kulit Jeruk Nipis (citrus
Aurantiifollia (Cristm.) Swingle) Menginduksi Apopotosis Pada sel Payudara Tikus
Galur Spraygue Dawley Terinduksi 7, 12-Dimetilbenz[a]antrasena, Proceeding
Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, , ISBN: 978-979-95108-6-0,
ISFI, pp. 94 – 99.
N. Puspita, Mita A., Fina A.G., E. P. Septisetyani, dan E. Meiyanto, 2008, Ekstrak
Etanolik Kulit Jeruk Mandarin (Citrus Reticulata) Meningkatkan Ekspresi Faktor
Angiogenik VEGF pada Sel Kanker Kolon WiDr, Proceeding Kongres Ilmiah XVI
Ikatan Sarjana Farmasi Indonesia, ISBN: 978-979-95108-6-0, ISFI, pp. 50 – 54.
Perdana Adhi N., Diah Ayu P.K.W, Andita P.D., Sugeng Riyanto, dan Edy Meiyanto,
2008, Penelusuran Mekanisme Penekanan Ekspresi N-Ras Ekstrak Etanolik Kulit
Jeruk Keprok (Citrus reticulata) Sebagai Agen Kemopreventif Docking Molekuler
pada Protein Target C-SRC dan CYP1A2, Proceeding Kongres Ilmiah XVI Ikatan
Sarjana Farmasi Indonesia,ISBN: 978-979-95108-6-0, ISFI, pp. 184 – 192.
Rifki Febriansah, Aditya Asyhar, Rosana Anna A., Ratna Asmah S., Muthi’ Ikawati,
dan Edy Meiyanto, 2008, Ekstrak Etanolik Rumput Mutiara (Hedyotis corymbosa)
Berefek Antiproliferasi Terhadap Sel Hepar Tikus Galur Spraygue Dawley
Terinduksi 7, 12 Dimetil Benz(a)antrazena Melalui Penghambatan Ekspresi Protein
c-Myc, Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, ISBN: 978-
979-95108-6-0, ISFI, pp. 88 – 93.
Ulfia Mutiara S., Septi Embun S.A., Navista Sri.O.U., Ratna Asmah S, Muthi’Ikawati,
dan Edy Meiyanto, 2008, Kajian Molekuler Senyawa Aktif Ekstrak Etanolik
Hedyotis Corymbosa pada Protein Era Serta Efek Antiproliferasinya terhadap Sel
Kanker Payudara Tikus Galur Sprague Dawley Terinduksi 7, 12 Dimetil
15
Benz(a)antrasena, Proceeding Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia,
ISBN: 978-979-95108-6-0, ISFI, pp. 62 – 69.
Yustina E.H., Ratih H.P., Y. Gilang Ikhtiarsyah dan Edy Meiyanto, 2008, Peningkatan
Aktivitas Antiproliferatif Doxorubicin melalui Kombinasi dengan Ekstrak Etanolik
Kulit Batang Waru ( Hibiscus Tiliaceus ) terhadap Sel WiDr, Proceeding Kongres
Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, ISBN: 978-979-95108-6-0, ISFI, pp. 42
– 49.
Hamid, IS., Sugiyanto, Meiyanto, E., and Widyarini S., 2008, Ekspresi p53 pada
kelenjar mammae tikus galur Sprague Dawley setelah inisiasi DMBA dan pemberian
kemopreventif Gynura procumbens, Media Ked Hewan, 24(3): 171-176.
Meiyanto E., Sri Handayani, dan Riris Istighfari Jenie, 2008, Ekstrak etanolik kacang
panjang (Vigna sinensis (L) Savi ex Hassk) meningkatkan proliferasi sel epitel
payudara dan perkembangan kelenjar payudara melalui peningkatan ekspresi
reseptor estrogen. Indon. J. Pharm, 19(4):191-197.
Adelina R., Supriyati MD., Nawangsari DA., Jenie RI., and Meiyanto E., 2008, Citrus
reticulata’s peels modulate blood cholesterol profile and increase bone density of
ovariectomized Rats, Indon. J. Biotechnol., 13 (2): 1092-1097.
2009
Meiyanto E., Handayani S., Susidarti RA., and Jenie RI, 2009, Chloroform fraction of
Areca (Areca catechu L.,) Induces apoptosis an decreases BCl-2 expression on MCF-7
cells, Mal. J. Pharm., Vol 1 (7): 290-294.
Meiyanto E., Sri Handayani, RA Susidarti, and EP Septisetyani, 2009, Areca (Areca
catechu L.) Seeds Ethanolic extract and its chloroform fraction increase apoptotic
effect of doxorubicin on MCF-7 cells, j. ilm.Farm. Ind., vol-7 No.1: 13-18.
Kumala, S., Septisetyani EP., and Meiyanto, E., 2009, n-buthanolic fraction of
endophitic microbes of Brucea javanica increases apoptotic effect of doxorubicin on
MCF-7 cells, Indon. J. Pharm, 20(1): 42-47.
Hamid, IS., Sugiyanto, Meiyanto, E., and Widyarini S., 2009, Ekspresi CYP1A1 dan
GATM hepatosit terinduksi DMBA dan pengaruh pemberian kemopreventif Gynura
procumbens, Indon. J. Pharm, 20(4): 198-206.
16
Haryanti S., Junedi S., and Meiyanto E., 2009., Ethonolic Extract of Heydotis
Corymbosa L. Increases Cytotoxic Activity of Doxorubicin on MCF-7 Breast Cancer
Cells., Indonesian Journal of Biotechology, vol. 12, No. 2, 1146-1154.
2010
Fitriasari, A., Susidarti, RA., Meiyanto, E., 2010, Peningkatan Efek Sitotoksik
Doxorubicin oleh Naringenin Melalui Pemacuan Apoptosis Sel Kanker Payudara
MCF-7, Jurnal Bahan Alam Indonesia, Vol.7, No. 3, p. 165-170.
Kumala, S., Meiyanto, E., Ikawati, M., Jenie, RI., 2010, Sinergisme Fraksi Butanol
Metabolit Skunder Kapang Endofit 1.3.11 dengan Doxorubicin dalam Modulasi Daur
Sel T47D dan MCF-7, Jurnal Ilmu Kefarmasian Indonesia, Vol. 8, No. 1, p. 1-9.
Kumala, S., Septiseptyani, EP., Meiyanto, E., 2010, Cytotoxic effect of secondary
metabolites produced by endopytic fungi 1.3.11, 1.1.6 and 1.2.6 isolated from the
fruit of “Tanaman Buah Makassar” (Brucea janvanica (l.) Merr) on in-vitro T47D and
MCF-7 intact cells and identification of the fungus 1.3.11 by ribosomal DNA
sequence analysis, International Journal of Pharmacy and Pharmaceutical Sciences,
Vol 2 Issue 2, p. 80-83.
Hermawan, A., Meiyanto E., and Susidarti, RA., 2010, Hesperidin meningkatkan efek
sitotoksik doxorubicin pada sel MCF-7, Indon. J. Pharm, 21(1): 8-17.
Junedi, S., Susidarti, RA., dan Meiyanto, E., 2010, Peningkatan Efek Sitotoksik
Doxorubicin oleh Naringenin pada Sel Kanker payudara T47D melalui Induksi
Apoptosis, Indonesian Journal of Pharmacy, Vol. 8., No., 2, p:85-90.
Ekowati, J., Rudyanto, M., Sasaki, S., Budiati, T., Sukardiman, Hermawan, A., and
Meiyanto, E, 2010, Structure Modification of Ethyl p-methoxycinnamate Isolated
from Kaempferia galanga Linn. and Citotoxicity Assay of The Products on WiDr cell,
Indonesian Journal of cancer Chemoprevention, Vol 1., No 1., p:12-18.
Armandari, I., Palupi, KD., Farida, S., Hermawan, A., Susidarti, RA., and Meiyanto, E,
2010, Synergistic Combination of Ciplukan (Physalis angulata) Herbs Ethanolic
Extract and Doxorubicin on T47D Breast Cancer Cells, Indonesian Journal of cancer
Chemoprevention, Vol 1., No 1., p:26-31.
Istiaji, RP., Fitria, M., Larasati, Tjondro F., , Maruti, AA., Setyowati, EP., and
Meiyanto, E,, 2010, Leunca (Solanum nigrum L.) Herbs Ethanolic Extract Increase
17
Cytotoxic Activity of Cisplatin on Hela Cervical Cancer Cells, Indonesian Journal of
cancer Chemoprevention, Vol 1., No 1., p:32-37.
Anindyajati, Sarmoko, Putri, DDP., Hermawan, A.,, and Meiyanto, E, 2010,
Combination of Solanum nigrum L., Herb Ethanolic Extract and Doxoorubicin
Performs Synergism on T47D Breast Cancer Cell Line, Indonesian Journal of Cancer
Chemoprevention, Vol. 1, No.2, p:78-84.
Nur, KA., Putri, H., Cahyani, FM., Katarina, Aulia., Susidarti, RA., and Meiyanto, E,
2010, Ethanolic extract of Moringa oleifera L., Increases Sensitivity of WiDr colon
cancer line towards 5-Fluorouracil, Indonesian Journal of Cancer Chemoprevention,
Vol. 1, No.2, p:124-128.
2011
Kasianningsih, S., Rivanti, E., Pratama, RH., Pratama, NR., Ikawati, M., Meiyanto, E.,
2011, Taraxacum Officinale Leaves Ethanolic Extract As Immunostimulatory Agent
for Reducing Side Effect of Doxorubicin in Sprague Dawley Rats, Indonesian Journal
of Cancer Chemoprevention, Vol. 2, No.1, p:135-140.
Pratama, NR., Ikhtiarsah, YG., Riata, R., Hermawan, A., Ikawati, M., Meiyanto, E.,
2011, Banana Peels (Musa paradisiacal L.) Extract as Phytoestrogen on
Ovariectomized Mice Mammary Gland Development by Inducing c-Mycy Expression,
Indonesian Journal of Cancer Chemoprevention, Vol. 2, No.1, p:151-159.
Meiyanto, E., Hermawan, A., Anindyajati, 2011, Translational Research in Cancer
Drug Development, Indonesian Journal of Cancer Chemoprevention, Vol. 2, No.2,
p:198-210.
Monikawati, A., Farida, S., Putri, LW., Ikhtiarsyah, YG., Meiyanto, E., 2011,
Antiproliferative Activity of Ethanolic Extract of Ciplukan Herbs (Physalis angulata
L.) on 7, 12-dimethylbenz[a]nthracene-induced Rat Mammary Carcinogenesis,
Indonesian Journal of Cancer Chemoprevention, Vol. 2, No.2, p:227-232.
Kusharyanti, I., Larasati, Susidarti, RA., Meiyanto, E. 2011, Hesperidin Increase
Cytotoxic Activity Of Doxorubicin On Hela Cell Line Through Cell Cycle Modulation
And Apoptotis Induction, Indonesian Journal of Cancer Chemoprevention, Vol. 2, No.2,
p:267-273.
18
Meiyanto,E., Fitriasari, A., Hermawan, A., Junedi, S., Susidarti, RA., 2011, The
improvement of doxorubicin activity on breast cancer cell lines by tangeretin
through cell cycle modulation, Oriental Pharmacy and Experimental Medicine DOI
10.1007/ s13596-011-0016-4.
Meiyanto,E, Hermawan, A., Junedi, S., Fitriasari, A., Susidarti, RA., 2011, Nobiletin
Increased Cytotoxic Activity Of Doxorubicin On Mcf-7 Cells But Not On T47d Cells,
International Journal of Phytomedicine 3 (2011) 129-137.
Nurrochmad, A., Lukitaningsih,E., Meiyanto, E., 2011, Anti cancer activity of rodent
tuber (Thyphonium flagelliforme (lodd.)Blume on human breast cancer t47d cells,
International Journal of Phytomedicine 3 (2011) 138-146.
Pratama, RH., Ikhtiarsyah, YG., Anindyajati, Fitriasari, A., Ikawati, M., Meiyanto, E.
2011, Ekstrak Etanolik Daun Awar-awar (Ficus septic Burm F.) secara Sinergis
Meningkatkan Efektifitas Doxorubicin terhadap Sel Kanker Payudara T47D, Jurnal
Ilmu Kefarmasian Indonesia, Volume 9 Nomor 1 (hlm. 67-71).
Meiyanto, E., Hermawan, A., and Anindyajati, 2011, Translational Research in
Cancer Drug Development, Indonesian Journal of Cancer Chemoprevention, 2(2):198-
210.
Fitria, M., Armandari, I., Septhea, DB., Ikawati, A.H.M., and Meiyanto, E., 2011,
Ektrak etanolik Herba Ciplukan (Physalis angulata L.) Berefek Sitotoksik dan
Menginduksi Apoptosis pada Sel Kanker Payudara MCF-7, Bionatura Jurnal Ilmu-
Ilmu Hayati dan Fisik, Vol. 13 No. 2, p:101-107.
Nugroho, A.E., Ikawati, M., Hermawan, A., Putri, D.D.P., and Meiyanto, E., Cytotoxic
Effect of Ethanolic Extract Fractions of Indonesia Plant Ficus septica Burm. F. on
Human Breast Cancer T47D cell lines, International Journal of Phytomedicine Vol. 3,
p: 216-226.
Hermawan, A., Murwanti, Artanti, N., Meiyanto, E., 2011, Effect of the water
extract of Macrosolen cochinchinensis (Lour.) Tiegh. leaves on 7,12dimethylbenz
[a] antracene induced female mice liver carcinogensis, Journal of Chinese
Pharmaceutical Sciences 20 (2011) 627–632.
Darma, AP., Ashari, R.A., Nugroho, P.A., Monikawati, A., Fauzi, I.A., Hermawan, A., and
Meiyanto, E., 2011, Aktivitas Sitotoksik Ekstrak Etanolik Herba Ciplukan (Physalis
19
angulata L.) Pada Sel Kanker Leher Rahim HeLa Melalui Modulasi Ekspresi Protein
p53, Farmasains Jurnal Farmasi dan Ilmu Kesehatan, Volume 1 Nomor 2, p:103-112.
Palupi KD., Ainun Wulandari., Fina Aryani Goenandi., Kholid Alfan Nur., Aditya
Fitriasari, Edy Meiyanto. 2011. Efek Sititoksik ekstrak Etanolik Herba Seledri
( Apium graveoulus L) pada sel kanker T47D, WiDr, dan Hela. Volume 1 Nomor 2,
p:113-137.
2012
Nurulita, N.A.,Meiyanto, E., Sugiyanto, Matsuda, E., and Kawaichi, M., 2012, Gynura
procumbens Modulates the Microtubules Integrity and Enhances Distinct
Mechanism on Doxorubicin and 5-Fluorouracil-induced Breast Cancer Cell
Death,Orient. Pharm. Exp. Med., DOI 10.1007/s13596-012-0063-5. Published online:
23 Feb 2012.
Sugiyanto, B. Sudarto, Meiyanto, E., Nugroho, A.E.,and Jenie, U.A., 2003, The
Anticarcinogenic Activity of Plants Compounds, MFI, 14 (4): 216-225.
Fithriyatun Nisa, Adam Hermawan, Retno Murwanti, Edy Meiyanto, 2012,
Antiproliferative effect of gynura procumbens (lour.) Merr. Leaves etanolic extract on
7,12-dimethylbenz(a)antracene induced male rat liver, Advanced Pharmaceutical
Bulletin, 2(1), 99-106.
Endang Purwaningsih, Sri Kadarsih Soejono, Djaswadi Dasuki and Edy Meiyanto,
2012, Curcumin inhibits luteal cell steroidogenesis by suppression of extracellular
signal regulated kinase. Universa Medicina, 31(2): 73-80.
Agung Endro N, Adam Hermawan, Dyaningtyas Dewi PP., Edy Meiyanto, Lukmasn
Hakim., 2012. Synergistic effect of ethyl acetate fraction on Ficus septica Burm.f. and
doxorubicin chemotherapy on T47D human breast cancer cell line. Journal of
Chinese Integrative Medicine , Vol. 10 No. 10: 1162-1170.
Sri Handayani, Chandra Risdian, Edy Meiyanto, Zalinar Udin, Rina Andriyani, and
Marissa Angelina., 2012., Selaginella Active Fractions Induce Apoptosis on T47D
Breast Cancer Cell., Indonesian Journal of Pharmacy., Volume 23 Issue 1 : 48-53.
Agung Endro Nugroho, Adam Hermawan, Kunti Nastiti, Suven, Pritha Elisa, Tony
Hadibarata, Edy Meiyanto. Immunomodulatory Effects of Hexane Insoluble
20
Fraction of Ficus septica Burm. F. in Doxorubicin-treated Rats. Asian Pacific Journal
of Cancer Prevention, 2012 : Vol 13 (11) : 5785-5790.
Agung Endro Nugroho, Adam Hermawan, Dyaningtyas Dewi Pamungkas Putri and
Edy Meiyanto, 2012, Combination Effects of Hexane Insoluble Fraction of Ficus
septica Burm. F. and Doxorubicin Chemotherapy on T47D Breast Cancer Cell
Lines, Asian Pacific Journal of Tropical Biomedicine, 3(4):297-302.
Nurulita, N.A.,Meiyanto, E., Sugiyanto, Matsuda, E., and Kawaichi, M., 2012, Gynura
procumbens Prevents Chemoresistance through Inhibition MDR1 Expression on
MCF-7 Breast Cancer Cell Line and Sensitizes the Cells to Doxorubicin, Indonesian
Journal of Biotechnology, Vol. 17, No. 1, pp.51-60.
Adam Hermawan, Kholid Alfan Nur, Sarmoko, Dyaningtyas Dewi, Pamungkas Putri,
Edy Meiyanto. Ethanolic extract of Moringa oleifera increased
cytotoxic effect of doxorubicin on HeLa cancer cells. Journal of Nature Remedies. Vol.
12/2 (2012)108-114.
2013
Agung Endro Nugroho, Adam Hermawan, Dyaningtyas Dewi Pamungkas Putri,
Anindya Novika, Edy Meiyanto. Combinational effects of hexane insoluble fraction
of Ficus septica Burm. F. and doxorubicin chemotherapy on T47D breast cancer cells.
Asian Pac J Trop Biomed 2013; 3(4): 297-302.
Sri Handayani, Adam Hermawan, Edy Meiyanto, Zalinar Udin. Induction of
Apoptosis on MCF-7 cells by Selaginella Fractions. Journal of Applied
Pharmaceutical Science Vol. 3 (04), pp. 031-034, April, 2013.
Muhammad Da’i, Arry Yanuar, Edy Meiyanto, Umar Anggara Jeniec and Amir
Margono Supardjan. (2E,5E)-2,5-Bis(4-hydroxy-3-
methoxybenzylidene)cyclopentanone ethanol monosolvate. Acta Cryst. (2013). E69,
o530.
Ari Widiyantoro, Thamrin Usman, Edy Meiyanto, Sabirin Matsjeh. Cytotoxic Activity
of Crude Extracts and Fractions from Irvingia malayana. IOSR Journal Of Pharmacy.
Volume 3, Issue 4 (May 2013), Pp 05-08.
21
2014
Meiyanto E, Putri DD, Susidarti RA, Murwanti R, Sardjiman, Fitriasari A, Husnaa U,
Purnomo H, Kawaichi M. Curcumin and its Analogues (PGV-0 and PGV-1) Enhance
Sensitivity of Resistant MCF-7 Cells to Doxorubicin through Inhibition of HER2 and
NF-kB Activation. Asian Pac J Cancer Prev. 2014. 15(1):179-84.
Rifki Febriansah, Dyaningtyas Dewi Pamungkas Putri, Sarmoko, Nunuk Aries
Nurulita, Edy Meiyanto, Agung Endro Nugroho. Hesperidin as a preventive
resistance agent in MCF-7 breast cancer cells line resistance to doxorubicin. Asian
Pac J Trop Biomed 2014; 4(3): 228-233.
Anugerah Budipratama Adina, Fina Aryani Goenadi, Franciscus Feby Handoko, Dwi
Ana Nawangsari, Adam Hermawan, Riris Istighfari Jenie and Edy Meiyanto.
Combination of Ethanolic Extract of Citrus aurantifolia Peels with Doxorubicin
Modulate Cell Cycle and Increase Apoptosis Induction on MCF-7 Cells. Iranian
Journal of Pharmaceutical Research (2014), 13 (3): 919-926.
Adam Hermawan, Anugerah Budipratama Adina, Fina Aryani Goenadi, Fransiscus
Feby Handoko, Dwi Ana Nawangsari, Riris Istighfari Jenie, and Edy Meiyanto.
Combination of Ethanolic Extract of Citrus aurantifolia Peels with Doxorubicin
Modulate Cell Cycle and Increase Apoptosis Induction on MCF-7 Cells. Iranian
Journal of Pharmaceutical Research. 2014.
Ratna Asmah Susidarti, Riris Istighfari Jenie, Muthi’ Ikawati, Dyaningtyas Dewi
Pamungkas Putri, Edy Meiyanto. Cytotoxic activity and apoptosis induction of 8-
hydroxyisocapnolactone-2´,3´-diol and its combination with Doxorubicin on MCF-7
and T47D cells. Journal of Applied Pharmaceutical Science Vol. 4 (06), pp. 089-097,
June, 2014.
Sarmoko, Dyaningtyas Dewi Pamungkas Putri, Ratna Asmah Susidarti, Agung Endro
Nugroho, Edy Meiyanto. Increasing Sensitivity Of Mcf-7/Dox Cells Towards
Doxorubicin By Hesperetin Through Suppression Of P-Glycoprotein Expression.
Indonesian J. Pharm. Vol. 25 No. 2 : 84 – 90.
Yonika Arum Larasati, Dyaningtyas Dewi Pamungkas Putri, Rohmad Yudi Utomo,
Adam Hermawan, Edy Meiyanto. Combination of Cisplatin and Cinnamon Essential
Oil Inhibits HeLa Cells Proliferation through Cell Cycle Arrest. J App Pharm Sci. 2014;
4(12): 014-019.
22
Edy Meiyanto, Herwandhani Putri, Yonika Arum Larasati, Ria Fajarwati.
Pengembangan Boron Carrying Pharmaceuticals untuk Mendukung Terapi Kanker
Berbasis BNCT. Prosiding Pertemuan dan Presentasi Ilmiah-Penelitian Dasar Ilmu
Pengetahuan dan Teknologi Nuklir PSTA Batan. 2014: 156-162.
2015
N.P. Linda Laksmiani, R. Asmah Susidarti, Edy Meiyanto. Brazilein Increases the
Sensitivity of Doxorubicin on MCF-7 Resistant Doxorubicin (MCF-7/DOX) Cells
Through Inhibition of HER-2 Activation. International Journal of Pharmacy and
Pharmaceutical Sciences. 2015. Vol 7, Issue 2, 525-528.
Adam Hermawan, Retno Murwanti, Nina Artanti, Edy Meiyanto. Effect of the Water
Extract of Macrosolen Cochinchinensis (Lour.) Tiegh. Leaves on 7, 12-dimethylbenz
[a] antracene induced female mice liver carcinogensis. 2015. Journal of Chinese
Pharmaceutical Sciences. 20 (2011) 627-632.
Ni Putu Linda Laksmiani, Ratna Asmah Susidarti, Edy Meiyanto. Brazilein Increased
Cytotoxic Activity of Doxorubicin on MCF-7/DOX Cells. Indonesian Journal of Cancer
Chemoprevention. 2015. 6(2): 58-63.
Astrid Ayu Maruti, Fikri Amalia, Edy Meiyanto. Synergistic Effect of Arecoline in
Combination with Doxorubicin on HeLa Cervical Cancer Cells. Indonesian Journal of
Cancer Chemoprevention. 2015. 6(2): 64-70.
Prisnu Tirtanirmala, Annisa Novarina, Rohmad Yudi Utomo, Raisatun Nisa Sugiyanto, Riris Istighfari Jenie, Edy Meiyanto, 2015, Cytotoxic and Apoptotic-inducing Effect of Fraction Containing Brazilein from Caesalpinia sappan L. and Cisplatin on T47D Cell Lines, Indonesian Journal of Cancer Chemoprevention, Vol. 6, No.3, p:89-96.
2016
Ika Rahmawati Sutejo, Herwandhani Putri, Edy Meiyanto. The Selectivity of
Ethanolic Extract of Buah Makassar (Brucea javanica) on Metastatic Breast Cancer
Cells. 2016. Journal of Agromedicine and Medical Sciences. Vol 2, Issue 1, 1-6.
Herwandhani Putri, Riris Istighfari Jenie, Ria Fajarwati Kastian, Edy Meiyanto.
Combination of Potassium Pentagamavunon-0 and Doxorubicin Induces Apoptosis
23
and Cell Cycle Arrest and Inhibits metastasis in Breast Cancer Cells. Asian Pac J
Cancer Prev. 2016. 17(5), 2683-8.
Rul Afiyah Syarif, Sri Kadarsih Soejono, Edy Meiyanto, Mae Sri H Wahyuningsih.
Effects of Curcumin on Estrogen Secretion and Estrogen Receptor β in Pig Granulosa
Cells of Medium Follicles. 2016. Jurnal Kedokteran Brawijaya. Vol 29, No.1 : 32-38.
Sari Haryanti, Suwijiyo Pramono, Retno Murwanti, Edy Meiyanto. The Synergistic
Effect of Doxorubicin and Ethanolic Extract of Caesalpinia sappan L. Wood and Ficus
septica Burm.f. Leaves on Viability, Cell Cycle Progression, And Apoptosis Induction
of MCF7 Cells. Indonesian Journal of Biotechnology. Vol 21, No.1 : 29-37.
Sri Handayani, Ratna Asmah Susidarti, Zalinar Udin, Edy Meiyanto, Riris Istighfari
Jenie. Brazilein in Combination with Cisplatin Inhibit Proliferation and Migration on
Highly Metastatic cancer Cells, 4T1. 2016. Indonesian Journal of Biotechnology. Vol
21, No. 1: 38-47.
2017
Sri Handayani, Ratna Asmah Susidarti, Riris Istighfari Jenie, Edy Meiyanto. Two
Active Compunds from Caesalpinia sappan L. in Combination with Cisplatin
Synergistically Induce Apoptosis and Cell Cycle Arrest on Widr Cell. 2017. Advanced
Pharmaceutical Bulletin. Vol 7, No. 3: 375-380.
Sari Haryanti, Retno Murwanti, Herwandhani Putri, Gagas Pradani Nur Ilmawati,
Suwijiyo Pramono, Edy Meiyanto. Different 4T1 Cells Migration under Caesalpinia
sappan L. and Ficus septica Burm.f Ethanolic Extracts. 2017. Indonesian Journal of
Cancer Chemoprevention. Vol 8, No. 1: 21-26.
Riris Istighfari Jenie, Sri Handayani, Ratna Asmah Susidarti, Zalinar Udin, Edy
Meiyanto. Cytotoxic and Antimetastasis Effect of Ethyl Acetate Fraction from Caesal
pinia sappan L. on MCF-7/HER2 Cells. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol. 8, No. 1: 42-50.
Rohmad Yudi Utomo, Herwandhani Putri, Pudjono, Ratna Asmah Susidarti, Riris
Istighfari Jenie, Edy Meiyanto. Synthesis and Cytotoxic Activity of 2,5-Bis(4-Boronic
Acid)Benzylidine Cyclopentanone on HER2 Overexpressed-Cancer Cell. 2017.
Indonesian Journal of Pharmacy. Vol 28 No 2: 74-81.
24
Ulfatul Husnaa, Ni Putu Linda Laksmiani, Ratna Asmah Susidarti, Edy Meiyanto.
Ethyl Acetate Fraction of Caesalpinia sappan L. Enhances Cisplatin’s Cytotoxicity on
HeLa Cells via G1 and S Arrest through p53 Expression. 2017. Indonesian Journal of
Cancer Chemoprevention. Vol 8, No. 2: 51-60.
Nur Dina Amalina, Ika Putri Nurhayati, Edy Meiyanto. Doxorubicin Induces
Lamellipodia Formation and Cell Migration. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol 8, No. 2: 61-67.
Beni Lestari, Dhania Novitasari, Herwandhani Putri, Sari Haryanti, Ediati Sasmito,
Edy Meiyanto. Evaluation of The Genotoxicity of Three Food Additives using CHO-
K1 Cells under in vitro Micronucleus Flow Cytometry Assay. 2017. Indonesian
Journal of Cancer Chemoprevention. Vol 8, No. 2: 74-80.
Nur Fitra Sari, Beni Lestari, Dian Saputri, Anisa Fauzia Ahsani, Ragil Anang Santoso,
Ediati Sasmito, Edy Meiyanto. Reveal Cytotoxicity and Antigenotoxicity of Piper
nigrum L. Ethanolic Extract and its Combination with Doxorubicin on CHO-K1 Cells.
2017. Indonesian Journal of Cancer Chemoprevention. Vol. 8, No. 3: 110-119.
Devi Nisa Hidayati, Riris Istighfari Jenie, Edy Meiyanto. Combination of Curcuma
(Curcuma xanthorriza Roxb) hizome Ethanolic Extract and Awar-awar (Ficus
septica Burm. F) Leaves Ethanolic Extract Increases Cisplatin Cytotoxicity on T47D
Breast Cancer Cells through Cell Cycle Modulation. 2017. Indonesian Journal of
Cancer Chemoprevention. Vol. 8, No. 3: 120-125.
Asri Mega Putri, Nindya Budiana Putri, Rahmawaty Rachmady, Idlohatud Dilalah,
Retno Murwanti, Edy Meiyanto. Secang Heartwood Ethanolic Extract (Caesalpinia
sappan L.) Inhibits Mesenchymal Stem Cells Senescene. 2017. Indonesian Journal of
cancer Chemoprevention. Vol. 8, No. 3: 126-134.
Yoce Aprianto, Asri Mega Pratiwi, Hilyatul Fadliyah, Retno Murwanti, Edy
Meiyanto. Abtigenotoxic Activity of Rumput Mutiara (Hedyotis corymbosa L.)
Ethanolic Extract on Cyclophosphamide-Induced Mice. 2017. Indonesian Journal of
Cancer Chemoprevention. Vol. 8, No. 3: 135-145.
2018
Edy Meiyanto, Endah Puji Septisetyani, Yonika Arum Larasati, Masashi Kawaichi.
Curcumin Analog Pentagamavunon-1 (PGV-1) Sensitizes Widr Cells to 5-Flurouracil
25
through Inhibition of NF-kB Activation. 2018. Asian Pacific Journal of Cancer
Prevention. Vol. 19, No. 1: 49-56.
Yonika Arum Larasati, Noriko Yoneda-Kato, Ikuko Nakamae, Takashi Yokoyama,
Edy Meiyanto, Jun-ya Kato. Curcumin Targets Multiple Enzymes Involved in the
ROS Metabolic Pathway to Seppress Tumor Cell Growth. 2018. Scientific Reports 8:
2039.
18. Aktivitas Riset dan Seminar Internasional (sejak 2002)
1. Oral presentation at The Asia Pacific Organization on Cancer Prevention
(APOCP) Conference, Nagoya, Japan, 2002
2. Visiting Scientist at Nara institute of Science and Technonogy, Japan, October
2002
3. Visiting Scientist at Nara institute of Science and Technonogy, Japan, October
2004
4. Oral presentation at the international seminar on Cancer diagnostic and
theraphy , Yogyakarta-Indonesia, 2005
5. Oral presentation at the 21st congress of Federation of Asian Pharmaceutical
Associations, Yokohama-Japan, 2006
6. Oral presentation at the international symposium on recent progress in
curcumin research, Yogyakarta-Indonesia-2006
7. Oral presentation at the international seminar on the Henk Timmerman :
Structure based Drug Development, LIPI-Indonesia, 2007
8. Oral presentation at the international seminar on Application of molecular
biology on drug discovery and medical diagnosis, Nov 28th 2008 Faculty of
Pharmacy Muhammadiyah University of Surakarta, Indonesia
9. Oral presentation at the International seminar on Drug discovery, March 16-
18, 2009, Makassar
10. Poster presentation at the International Kyoto Breast Cancer Consensus
Conference, Kyoto-Japan, 16-18 April 2009
11. Oral Presentation at the Conference of AASP-MPSPS Penang Malaysia, June
11-13, 2009
12. Oral presentation at the International Conference of Chemoprevention for
health and beauty, ISCC, Yogyakarta Oct 9, 2010
13. Speaker at the APPS, Yogyakarta, July 4, 2011
14. Speaker at the International seminar Natural Product for Cancer
Chemoprevention, UMP, Purwokerto, July 5, 2011
26
15. Presenter at OOTR the 8th Annual Conference, OOTR, Japan, April 20-22,
2012
16. Moderator and Committee at In the International Conference Research and
Application, UMS, Surakarta, June 22-23,2012
17. Presenter at The 5th Indonesia Biotechnology Conference an International
Forum “ Green Industrial Innovation Through Biotechnology”, Konsorsium
Bioteknologi Indonesia, Mataram July 4th-7th, 2012
18. Speaker at The 3rd International Conference on Pharmacy and Advanced
Pharmaceutical Science, Fakultas Farmasi UGM, Yogyakarta, June 18-19,
2013.
19. Presenter at 72nd Annual Meeting of The Japanese Cancer Association, JCA,
Japan, October 3-5, 2013.
20. Presenter at 73rd Annual Meeting of The Japanese Cancer Association, JCA,
Japan,September 25-27, 2014.
21. Speaker at MICAPS (Medan International Conference on Advance
Pharmaceutical Science) : Advanced Drug Development in Cancer
Chemoprevention and Metabolic Disorders, Medan, Sumatera Utara,
November 6-7th, 2014.
22. Speaker at PICAPS (Pontianak International Conference on Advance
Pharmaceutical Science), Pontianak, Kalimantan Barat, September 14-15th,
2015.
23. Presenter at 74th Annual Meeting of The Japanese Cancer Association, JCA,
Japan, October 08-10th, 2015.
24. Speaker at International Symposium on the Application of Nuclear
Technology to Support National Sustainable Development: Health,
Agriculture, Energy, Industry, and Environment, Satya Wacana Christian
University, Indonesia, October 26-28, 2015
25. Oral Presentation at 75th Annual Meeting of The Japanese Cancer Association,
JCA, Japan, October 6-8, 2016.
26. Speaker at WHICAPS (Wahid Hasyim International Conference on Advanced
Pharmaceutical Science), Semarang, November 7-8th, 2016.
27. Poster Presentation at 76th Annual Meeting of The Japanese Cancer
Association, JCA, Japan, September 28-30, 2017
28. Oral Presentation at The 2nd International Conference on Medicinal
Chemistry, Bandung, October 5-6, 2017
29. Invited Speaker at The 2nd Universitas Muhammadiyah Purwokerto
Pharmacy International Conference and 8th Indonesian Society of Cancer
Chemoprevention, Purwokerto, October 13-14, 2017
27
19. Patent
MEIYANTO EDY, ISHIDA NORIHIRO, TAKEYA TATSUO, MINENO JUNICHI,
ASADA KIYOZOU, and KATO IKUNOSHIN, 2004, JP Patent 2004147501:
METHOD FOR DETECTING DNA WITH HIGH SENSITIVITY, published in: 2004-
05-27
20. Penghargaan
1. Rektor Universitas Gadjah Mada: Pembimbing PIMNAS tahun 2006 bidang
PKMI (Medali Perak)
2. Menristek RI: Juara pertama bidang penelitian Ristek-MTIC 2007
3. REKTOR UGM: pembimbing penalaran mahasiswa 2007
4. Menristek RI : Juara Pertama Penghargaan Ristek Kalbe Science Award 2014
21. Pengalaman lain-lain
1. Sebagai wakil ketua dewan redaksi Majalah farmasi Indonesia (Terakreditasi
B)
2. Sebagai pembina penalaran Mahasiswa UGM (2007-2011)
3. Sebagai reviewer Jurnal Bahan Alam Indonesia (Terkreditasi B)
4. Sebagai Reviewer Nasional Program Kreativitas Mahasiswa (PKM) (2009-
sekarang)
5. Sebagai Reviewer hibah penelitian internal Fakultas dan Universitas
6. Sebagai Reviewer Indonesian Journal of Cancer Chemoprevention (2010-
sekarang)
Yogyakarta, Februari 2018
Prof. Dr. Edy Meiyanto, M.Si., Apt. NIP. 196205021989031006
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