dan egan, md meningitis and vice chair encephalitis...ann neurol. 2005 october ; 58(4): 594-604....
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Meningitis and Encephalitis
Dan Egan, MDVice Chair EducationColumbia
66K, 23/100K population, Median age 24
696
87%26%
5%
83%
33% 77%
Fever
AMSStiff Neck
44%
WBC > 500, LR 15
1000-5000
Lactate 3.5, LR 22.9 (12.6-41.9)
www.searchhomeremedy.com
2015
Hearing LossShort-term Neurologic SequelaeMortality from Strep pneumo only
Spring, 2009
20 yo F, college student. Finals week.Confused, trouble concentrating. Right hand twitching. Mild headache.Subjective fever.
AfebrileNormal examLP:270 WBC40 RBCAcyclovir, Admit
Parenchyma
WBC usually <500Glucose NORMALProtein up (<150)RBC with HSV
The story continues….
Anti-N-methyl-D-aspartate Receptor encephalitis (Anti-NMDAR)
Female:Male = 8:1Ages 8-84
Ovarian tumor 60% of women in childbearing age
Psych sx’s
Neuro sx’sAutonomic dysfunction
TRIAD
Antibodies in CSF
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