dermatology & oral disease laith akkash m.d consultant dermatologist, dermasurgeon &...
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Dermatology & Oral Disease
Laith Akkash M.D Consultant Dermatologist, Dermasurgeon & Allergist
Assistant professor of DermatologyJordan University Hospital
University of Jordan
• Dermatology
• Its relationship with oral diseases
• Histology of the Skin
• Histology of the mucous membranes
• Functions of mucous membranes
• Types of mucous membranes in the oral cavity
• Stratified squamous epithelium
• May or may not be keratinized
• Lamina propria is the underlying C.T. layer
• Submucosa
• Salivary glands
Oral mucosa can be subdivided into:
1-Masticatory mucosa: keratinized stratified squamous epithelium, found on the dorsum of the tongue, hard palate and attached gingiva.
2- Lining Mucosa: non-keratinized stratified squamous epithelium, found almost everywhere else in the oral cavity
3- Specialized mucosa: specifically in the regions of the taste buds on the dorsum of the tongue
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
1) Infections
A) Viral infections:
- Herpes Simplex
- Herpes Zoster
- Hand foot & mouth disease
- Warts –HPV
- HIV- Oral hairy leukoplakia
Cold sores
1ry herpes simplex
Oral warts
Oral hairy leukoplakia
Hand foot & mouth disease
1) Infections contd.
B) Bacterial:
- 1ry Syphilis
- 2ry Syphilis
- Gonococcal pharyngitis & Tonsillitis
- Actinomycosis
- TB
- Leprosy
1ry syphilitic chancre
2ry syphilis – mucous patch
Gonorrhea
Gonoccocal pharyngitis
1) Infections contd.
C) Fungal infections:
- Candidiasis
- Histoplasmosis
Oral Thrush - Candidiasis
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
2) Bullous diseases
- Pemphigus vulgaris
- Bullous pemphigoid
- Cicatricial pemphigoid
- Linear IgA disease
Pemphigus vulgaris
Pemphigus vulgaris
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
3) Connective tissue diseases
- Systemic lupus erythematosus
- Progressive systemic scleroderma
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
4) Allergic conditions
- Fixed drug eruption
- Allergic contact stomatitis
- Angioedema
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
5) Benign & Malignant Tumors
Benign- Naevi- Fibromas- Granular cell tumor- Hemangiomas- Lymphangiomas- Leiomyomas- Pyogenic granulomas
Malignant- Squamous cell ca.- Malignant melanoma- Sarcomas- Lymphomas
SCC lip
SCC -Ventral tongue
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
6) Genodermatosis
- Epidermolysis Bullosa
- Darier’s disease
Epidermolysis Bullosa
Relatively common disorders that may affect the mucous membranes1) Infections
2) Bullous diseases
3) Connective tissue diseases
4) Allergic conditions
5) Benign & Malignant tumors
6) Genodermatosis
7) other skin diseases
7) Others
- Lichen Planus- Behcet Disease- Aphthous ulcers- Fordyce disease- Mucocele- Angular cheleitis- White sponge naevus- Tongue diseases
Lichen Planus
Oral LP
Oral LP
Aphthous ulcers
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