innovative technologies of 3d-modelling in medicine

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AACIMP 2010 Summer School lecture by Dmitriy Gorlov (Materialise). "Information Technologies" stream. "Innovative Technologies of 3D-Modelling in Medicine" course. More info at http://summerschool.ssa.org.ua

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ИнновационныеИнновационные технологиитехнологии3d 3d моделированиямоделирования вв медицинемедицине

Innovative 3d modeling in medicine

Scope of the presentation…

• About Materialise• Technical introduction:- Starting from CT/MRI images, Mimics software can

make an accurate 3D reconstruction of the anatomical structures and export STL files.

- 3-matic software is capable of designing implants based on these 3D reconstructions, on STL level (no reverse engineering necessary)

- The final implants can be produced by Direct Metal Laser Sintering

Materialise UkraineMaterialise Ukraine• Office was established in August 2000 with 5

members on board in collaboration• Now we are more than 250 people !

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• Developers• Medical engineers

• Application engineers• CAD engineers

Welcome to Materialise

• Started in 1990 the technology of Rapid Prototyping (3D Printing)

• As in a joint venture with University of Leuven

• Grown to over 900 employees worldwide• HQ in Belgium, offices all around the world• Now active in diverse domains...

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Materialise Mission Statement

To innovate product development

resulting in a better and healthier world,

through its software and hardware infrastructure

and in-depth knowledge of Rapid Prototyping,

Tooling & Manufacturing.

3d printing: Rapid Prototyping

Materialise Factory

Materialise software products

What is Mimics?

• Mimics allows you to: • import scanned images • select structures in the images

• These structures can then be used for different applications…

CT or MRI Scan 2-D Cross Sections Mimics Software

3D Model

Prof. Dr. De Backer, UZ Antwerp, Dep. PneumologyProf. Dr. De Backer, UZ Antwerp, Dep. Pneumology

Mimics provides:

• A link between scanned images and...•• Rapid PrototypingRapid Prototyping•• CADCAD•• Finite Element AnalysisFinite Element Analysis•• Surgical Procedure SimulationSurgical Procedure Simulation

Rapid Prototyping

• Use Mimics for the production • of Medical Models

• Easy Creation of STL files• Direct export to RP formats• Create Supports in Mimics• Color stereolithography

• Medical Models:• Communication• Surgery Preparation• Proven to be very accurate

and useful • (cfr. Phidias – European

research project)Dr. George A. Brown

Kenneth E. Salyer, M.D., F.A.C.S., F.A.A.P., F.I.C.S.

Flexible soft tissue models

• Creation of flexible soft tissue models for device design

Angela NoeckerAngela Noecker, , Lerner Research InstituteLerner Research Institute

Design of custom implants

Ralf SchindelRalf Schindel, , Hochschule St. GallenHochschule St. Gallen

Non invasive archeology

Dominic Eggbeer, The National Centre for Product Design & Development Research (PDR)The British Museum

Other possibilities

Mimics provides:

• A link between scanned images and...•• Rapid PrototypingRapid Prototyping•• CADCAD•• Finite Element AnalysisFinite Element Analysis•• Surgical Procedure SimulationSurgical Procedure Simulation

Transfer to CAD

• Transfer geometries accurately from • scanned images to CAD software.

• (cfr. Aesculap study)

Case Study 1

• An Automated System for Design and analysis of Total Hip Implants

• Select information • Perform Statistics• Make new design

Mark A. Manasas - 1999

Mimics provides:

• A link between scanned images and...•• Rapid PrototypingRapid Prototyping•• CADCAD•• Finite Element AnalysisFinite Element Analysis•• Surgical Procedure SimulationSurgical Procedure Simulation

Finite Element Analysis

• Optimize your mesh for FE Analysis:

Finite Element Analysis

• Do an accurate material assignment to the volumetric mesh based on the HU in the CT images

Von Mises Stresses

Velocity pathlines from CFD

Computer Assisted Brain Analysis

Andreas A. Linninger, University of Illinois at Chicago

Mimics provides:

• A link between scanned images and...•• Rapid PrototypingRapid Prototyping•• CADCAD•• Finite Element AnalysisFinite Element Analysis•• Surgical Procedure SimulationSurgical Procedure Simulation

Surgical procedure Simulation

• Use Mimics to simulate the implant positioning • and to verify your design.

Data courtesy of Dr. Taha

Surgical procedure Simulation

• Use Mimics to gather measurements for e.g. statistical analysis

Wan Abdul Rahman Wan Harun, SIRIM Berhad

Implant placement and surgical simulation

MaterialiseThe design of a custom prosthesis

Classification of cranial prosthesis

1. ‘Simple’ Cranial defect

2. Large cranial defect

3. Missing orbit

1. Design for a simple cranial defect

Strategy - Example

• Draw a curve around the defect• Make sure you draw it far

enough from the border since we will make a tangential hole filling

• Use the “Create Cranioplasty Prosthesis” function

Curve

Result

2. Design for a large cranial defect

Example

Dr. Haex, AZ Maastricht

3. Design for missing orbit

Example

•The mirrored skull positioned at the desired spot

Dr. Taha, CHU Amiens

Example: verification in Mimics

Materialise – Kiev Office

Materialise: innovative products – innovative services – innovative careers

materialise.kiev.ua

Learn more about us!

Materialise Ukrainevul. Raisy Okypnoi, 8A · 02002 Kyiv ·UkraineTel. +38 044 594 5610

Fax +38 044 594 5611www.materialise.comwww.materialise.kiev.ua

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