presented by richard hill richard hill ma

From Behaviour to Brain to Gene

… and back again

Presented by

Richard Hill MA

www.richardhill.com.au

a woman without her man is nothing

• A woman, without her man, is nothing.

• A woman: without her, man is nothing.

Gene expressionEpigenetic silencing

• State dependent gene expression• Activity dependent gene

expression• Epigenetic marking – methylation,

acetylation. Access of transcription factors to promoter region.

• Nucleosome tension – ionic tightness.

We construct ourselves

From elemental materials

Over time

In response to experience

Becoming Human

DNA + experience

Biology + activity Behaviour

The deep psychobiological process of “activity or experience-dependent gene expression and brain plasticity” associated with creativity and psychotherapy.

Psychosocial Genomics

Interactive – responsive

biochemicals

Responsive to

experience – adaptive

Hierarchy of response

Responses are

remembered* meaning *

Self Organising SystemsInitial Conditions – DNA, polymorphisms

Organising Principles

Self Organising Systems

Optimal• Immune system• Associative brain• Positive emotions• Seeking• Social brain

Adaptation• Dis-integration• Hierarchy of needs• Habituation• Automation /

normalisation

How We RememberImplicit /

Explicit

Neuronal / Neural

Biological

Bio-chemical

Fascia

Muscles

Skin OrgansImmune System

Brain

Mind – Body MemoryConnected

systems

Implicit ExpressionBehaviour

Affect (emotionality /

mood)

PersonalityTemperament

Sense of Wellness -

pain

9 Voices

Skin Sleep Sun

Sugar Sitting Stress

Sex Pain Face

EMBODY

the

UNTRUE

TRUTH

ARGUE

the

UNTRUE

TRUTH

The Interplay

DNA + experience

Biology + activity Behaviour

The Interplay

BRAIN

BODY

Endocrine System

Neuropeptidespeptides

Autonomic System

Immunesystem

CNS (spinal) Vagus nerve

MINDThe Interplay

C.O.A.T. Curiosity Oriented Approach To…

That’s interesting

The problem is a message

What can I create from this

The Purpose of Life

To creatively participate in the experience

www.richardhill.com.au

richhill@iinet.net.au