project unity: the way of the future for plant breeding

Phenome Networks Confidential

Unleashing innovation through next generation bio-informatics

2

PLANT BREEDING COMPANIES GENERATE ENDLESS DATA

It is stored in sub-optimal datastores such as notes, excels and local solutions.

NO ONE HAS CONSOLIDATED ACCESS TO THE SUM OF DATA FROM PUBLIC RESEARCH

3

Phenome Networks Confidential

A large financial investment goes to waste

5,000STUDIES

$100KEACH

$500MINVESTMENT

4

Phenome Networks Confidential

Impossible today

Study

1

Study

2

Combinedinsights

1+2

5

What if we could standardize phenotype and genotype vocabulary?

• Linking genomics to traditional breeding• Share and compare data from multiple research groups

(standardization)• Link to other academic public-domain data

6

Phenome Networks Confidential

Genetic research works to correlate genotypes with phenotypes

MILLIONS OF GENETIC MARKERS

Onestudy, one

population

POPULATION /ENVIRONMENT

POPULATION / ENVIRONMENT

POPULATION / ENVIRONMENT

PH

EN

OT

YP

ES

Large investment

Vast amount of data

Complex analysis

7

Phenome Networks Confidential

Many research groups are working.In isolation.

MILLIONS OF GENETIC MARKERS

POPULATION /ENVIRONMENT

POPULATION / ENVIRONMENT

POPULATION / ENVIRONMENT

PH

EN

OT

YP

ES

Onestudy, one

population

8

Phenome Networks Confidential

Sharing and collaboration among multiple groups is challenging

?

HISDATA

ADHOCEXCELSHEET

PDF REPORTSMY

DATA

9

Phenome Networks Confidential

Missing crucial insights

MILLIONS OF GENETIC MARKERS

POPULATION /ENVIRONMENT

POPULATION / ENVIRONMENT

POPULATION / ENVIRONMENT

PH

EN

OT

YP

ES

Oneproject,

onepopulation

Other traits affected by my favorite marker?

Impact of my markers in other populations?

Are the effects consistent in different environments?

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Phenome Networks Confidential

Standardization is needed…

Phenotype Germplasm Genotype

Trait 1

Trait 2

Trait 3

Trait’s ontology

Unify scales

Germplasm 1

Germplasm 2

Germplasm 3

Pedigree relations

Define source

Marker 1

Marker 2

Marker 3

Link to genetic / physical map

Germplasm

Phenotype Genotype

Metadata on experiments / populations

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Phenome Networks Confidential

In an ideal world we want to innovate by integrating data from multiple sources

MILLIONS OF GENETIC MARKERS

POPULATION /ENVIRONMENT

POPULATION / ENVIRONMENT

POPULATION / ENVIRONMENT

PH

EN

OT

YP

ES

12

Phenome Networks Confidential

PublicPrivate

Giving Private Access to Public Data

Register, without central admins

Upload data

Analyze data

Integrate with public academic

data

Share data and

findings

21 3 4

Search dataSearch resultsCorrelateGet alerts

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Phenome Networks Confidential

UNITY: Aggregating all phenotypes / genotypes of all species in one place

PHENOME-NETWORKS

SGN GRAMENE NCBI PANZEA

PapersPapersPapers Papers

Papers

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Phenome Networks Confidential

UNITY: unleashing new insights by combining information about the world’s species

Study

1

Study

2

Combinedinsights

1+2

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Phenome Networks Confidential

We are in private beta.

For more information, go here:

http://phenome-networks.com/unity/