the mexican approach to conduct non-myeloablative stem cell … · 2020-05-01 · donor selection...
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Donor selection
Haplo versus cord
Resource limited environment
Donor registries
Domestic versus international
donor registries
Haplo versus cord
Placental blood
Four domestic public banks
Several private banks
Expensive cords from abroad (NMDP)
Poor quality of the domestic cords
Placental blood
Domestic cord: 3 000 USD
Imported cord: 30 000 USD
Restrictive
2006
68 placental blood allografts
Haploidentical allografts
vs
Hematology 2013, in the press
18 haploidentical allografts
cords
haplos
Haplos versus cords
Similar long term results
Haplos are cheaper (Cy)
No cord blood banks
More realistic in
underprivileged circumstances
Resource limited
environment
Centers participating in the CIBMTR 2011
SUM-WW11_2.ppt
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BBMT 2009; 15:1628
Traditional Mexican approach
Impossible
Impossible
++
++
Possible
Possible
+ / -
+
30 – 50%
300 000 USD
Difficult
17 %
20 000 USD
Possible
Self-recovery
Outpatient
Transfusions
GVHD
100-day mortality
Cost
Developing countries
Allografts
Donor registries
Donor registries
Domestic: DONORMO
• Less than efficient
• Transplant center restricted
• Expensive
International
• CRIR
• NMDP
….. this is the end-result of
sodality and friendship, two
uncommon values in a culture
driven by rivalry, jealousy,
disqualification, economic interest
and the zeal to reach that vacuum
known as success……
Julio Glockner
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