vuos company profile partner for cooperation. 2 22vuos – partner for cooperation where you can...
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VUOSCOMPANY PROFILE
PARTNER FOR COOPERATION
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22 VUOS – PARTNER FOR COOPERATION
Where you can find us
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VUOS ownership
AGROFERTHOLDING, a.s.
SYNTHESIA, a.s.
VUOS, a.s.
100% 100%
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History
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VUOS main businesses
2. Toxicology and Analytics
1. R&D and Production of Fine Chemicals
Employees
Sales in %
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The Certificates of VUOS
• ISO 9001:2008• Certificates of Good Laboratory
Practice
• Certificate of Accreditation for Certification of Products No. 229/2002 (EN 45011:1998)
• Certificate of Accreditation No. 230/2002 Testing Laboratory No. 1057 (EN ISO/IEC 17025:2005)
• Certificate on Compliance with Principles of Good Manufacturing Practice in laboratory
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Strong Points
• Education structure of employees
• VUOS is located in area of long-lasting chemical tradition and complete infrastructure
• Cooperation with University of Pardubice
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R&D, up scaling
• Pharmaceutical intermediates
• Intermediates for microelectronics
• Custom syntheses of chemical specialities
• Dyes and pigments for special application
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R&D, up scaling
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Wide range of quantitiesGrams – in laboratory
Kilograms – in kilolab
unitMetric tons – in VUOS
production plant
Hundreds of MT –
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VUOS ’s key chemistry
VUOS ’s key technology
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Adamantane derivatives
N-Heterocycles
API Building Blocks
PhosgenationHydrogenation
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VUOS ’s technology/manufactureexpertise includes:acetylationaldolisationamidationalkylationaminationamoxidationalkali fusionarylhydrazines synthesesazocouplingbenzoylationchiral synthesischlorinationchlorosulfonationcyclisationclaisen condensationdecarboxylation
dehydrohalogenationdiazotisationeliminationesterificationFriedel-Crafts reactionheterocyclic synthesishydrolysis reactionsneutralisationnitrationnitriles synthesesoxidation – catalytic/chemicaloxidation in liquid phaserearrangementreduction with hydrazine and sodium borohydridesulfonation
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Kilolab Unit
2x reactors, 250 and 650 l
2x High performance rectification columns
Laboratory phosgenation units from 1 to 30 litres
Phosgenation
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Kilolab Unit
3x autoclaves 100 l each, 60, 120 and 130 bar, up to 200 ˚C, Hastelloy C clad
1x autoclave 300 l, 120 bar, 140˚C, Hastelloy C clad
1x autoclave 700 l, 100 bar, 200 ˚C, stainless steel
1x autoclave 1 000 l, 10 bar, 140 ˚C, stainless steel many autoclaves up to 10 l
Hydrogenation
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Kilolab Unit
1 x glass reactor 50 l cooled down to – 80 ˚C
1x glasslined reactor for NaH reactions (250 l)
3x glass reactors 100l for RLi, Grignard reactions
Low temperature, RLi, RMgX, NaH
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Kilolab Unit
20x glass reactors, 100 l each
6x glass lined reactors (200–1 500 l)
2x evaporators 50 l / h
4x stainless steel reactors (300–1 500 l) sufficient filtration and distillation capacity
Multipurpose chemistry
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45x glass lined reactors, total vol. 70 000 l (500–5 000 l)
13x stainless steel reactors, total vol. 22 000 l (1 000–3,000 l)
8x High performance rectification columns
sufficient filtration capacity (nutsches, centrifuges)
computer controlled
Production Equipment
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Production Unit
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Toxicology, Ecologyand Analytics
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REAC Hand other legislative provisionsComplete Offer of Services by VUOS
•CONSULTING
•TESTING– Physico – chemical tests– Toxicological tests– Ecotoxicological tests
•EXPERT WORKS
•REGISTRATION
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Analytical techniques:•NMR Spectroscopy•Mass Spectrometry (LC/GC-MS)•ICP-AES•IR Spectroscopy•Chromatography (HPLC, GC)•UV-Vis
Toxicology, Ecologyand Analytics
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Toxicology, Ecologyand Analytics
Toxicology:In vivo and in vitro testing accordingto the OECD or EU methods:
•Acute toxicity test
•Skin and eye irritation
•Sensibilisation
•Repeated dose tests
•Reproduction toxicity tests
•Carcinogenicity
•Mutagenicity
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Toxicology, Ecologyand Analytics
Ecotoxicological testing:
In vivo and in vitro testing accordingto the OECD or EU methods:
•Aquatic toxicity•Biotic degradation – Ready biodegradability
•Inherent biodegradability
•Abiotic degradation
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Contacts
General Manager: Dr. Karel NovákPhone: +420 46 682 2550, fax: +420 46 682 2976e-mail: karel.novak@vuos.com
Sales Manager: Miloš Jesenský,Ph.D.Phone: +420 46 682 3300, fax: +420 46 682 2976e-mail: milos.jesensky@vuos.com
R&D: Alois Koloničný, Ph.D.Phone:+420 46 682 3156, fax: +420 46 682 3900e-mail: alois.kolonicny@vuos.com
Toxicology and Analytics: Viktor Mejstřík,
Ph.D.Phone:+420 46 682 3127, fax: +420 46 682 2975e-mail: viktor.mejstrik@vuos.com
Process Engineering: Luboš VíšekPhone:+420 46 682 5790, fax: +420 46 682 3900e-mail:lubos.visek@vuos.com
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