AN

INAUGURAL DISSERTATION

SUBMITTED TO THE

PRESIDENT, BOARD OF TRUSTEES, AND MEDICAL FACULTYOF TUE

(,,((,,(((

@l (((((((((((((((((((((

~

FOR THE DEGREE OF

I ••• I

\8Y'W. T. BERRY & CO.,

BOOKSELLERS AND STATIONERS,NASHVILLE, TENN.

-~ tt- ~z/~)

e1~~7#-a£-/~?/~iJ~ ~/~ "" L~7~ ~-~--~NL .tr!<;U&-<U-.. ~~--"~l

~ a- /h--un-kd /~ ~ ~ a.4~~7(!~a- 6t---2/fd ~c:.o-n4?-~~_

-.~a~ ~a-v-e <Y~ ~eL~;j,#"'/_d-~...u-:a.b ~~ ~ ~ __

-du~ 7~ /~ ~~ /a4-_L-~? c;/~ ~~ ~~ e;f'de-~J~~~.P --/~~e-cru--t-e- --<U' ~~ ~ ~-

~/~~£ed ~~_~ ~7~-/tLdift'~ ~ ~/~~ ~/~ ~/ ~ ~ /u# 7"~,if'//.:0; · ,~ -:/?7~ cw-e.-d, /dV7--t'UY~Mv'k'e 7d o/w-l'~ &r~~~~?~~

tl/Vt ffL. ~ ~ d- a.- c?//T'CbL- ~~ ;:;6/~ d47/Y7~ ~ eeue(&rne"ff~ ~ ~a:4~ a/l~ ,<4 ea-~&d~,

ffL0 ~~-z- r~ /-hJL-~ ~~~ ~ ;#:1&- d~

~d~d-~)~~0~d7~ a4&7~?~ ~ /a~~_-~~~7da/- ~ca:£~~.

a/U4-;;~p,YJ0~~~r=~ -/' ~~~~

~---<~d ~d $~- ~J ~ #e--~ /-H'~~ ~~-?d~ ~

~~/~7~e/f~~ ~~~J ~~a 7/P7~ /~

bf~h-~-~I!-4/' ~ ~

~~,~~~ t?/A'd ~ t?d~_/f~d,

~j~~~/U~~~~ C~a/Z-/~~ 4~d~~e"'j ~~ ~00-i'- ~ /~ ~

/~~ ;n{,vr~ 7 a:/'~4'-e~

( J)

aHL j'Jp-t!:;7;J? ~',---d: ~ L47~ 4'u!

~ /h'Z-e..e./- 4/'- ~ evJ-/7-r? //-7 ~J &/1/1d ~~-/Lr~,~ ~4~.-fb}-~~-pzJ. ~ )a/~ #?~a4;~L ~~ ~ ~eu/- /~/h'J~~~/H-~ ~4- ~~ d~/U-/~-b7~

cvre ~~(V~~.J k~~- /~~ ~~ d~j a- ~~/ ~~7 #.Eh~J~~

d~ #~~#~~ ~~~a/f-.

~ ~~CLd.e- A4 4'~~ d~~cLa4 ~a;; M/!~~~~/-00"//e~~

~ ~ /J--j;f~ (!vV?d ~/J.-e,L ~~

~~~~ A/r#~~-k ~/M-dfd' ad -#fe- /h?~/- da?-Cl~~~¥~ ~~. ~4/~~ cu-/--br4"aL~ed~/; ~ 4~4/JP?cJY ~ ~a~-

-~-~~krf ~CH-e~ ~ -d//A/Y/ae£-~

~-ba#~/-- ,d~J ~ ~d" ~~d' ~/~~ ~ ~d 4~ .&AA~

(it)

~--d~ d~~J~~O'-~~d4~r4de- £~~b?-dz~ 0/ ~ »~~~d.-4dd~~~ ~ eL/U~~4~-

_d~_ -h~a/-4/L--U~ ~ ff~)~~.v/- --o/-/.VJ-~;/~ ~;/o-d~~~~

~~~~~~~~~

~L U-H'dh~' ~ ._ /~~¥. f/k- ~v~-~ ~~~~

Af'P'M-",.u-ePL"-1-r~ /CUMo bid- dZ ~tl/Ua' L~~/J~~ ~w-eL ~ ~~OJ/' ~~--d~/~~~~ JJ/~ 4

~~ -i/jutdt a-~/ u/~ ~~ ~ ~~ ~~ 6uI a )17'tn-n4:-n"4~avtd/~£j{j;,2d-~~ ~~j du-

- Lau. · f!/5d /77 .URf ~e--H/d£trU '2i£k e&AA~ ~ ~~ cLt-u~ ~ ad ~t--

-~/f~d ~ (~d d ~8Vved~~~u.-~~r~ /ffel~a-~.J fl{~ ~• er/l4~£<-drk£4f u/~ -1;l~~~ 4a4r~

~a/~ .d:L7 ~~ cW a- O&~~4-;~

~~~. ~~~~~4:~ ~7/h~ud &4 a- /U~~~ 4~~/~LA- d- n!e- ~ /~:/ ~ dU~~~CVH- &~~A~~~ a-~

~~~cL ~et2'L ~£edA-~J 1?~~~ ~ #~d~~-~ ~d~~ ~~e~~~~4d:~~

~ ~/?~ ~ ~~7a/U- ~4~fU.ea!'

I-~~ a~ u/~ ~~~~~ /; ad~ _~ ~ ~d/~~~~~~b' ~~d -</'~~~

~ ~J a/--4~ ~ /j/ld~~ fi~~~ £ k ~tY'6d ~~ ~ d- ~J

~ ~~~~~~o;/~~--~~7 ~~J ~~ ~ ~d7~~ 4-h-k~ u-r ~~t'?-d-I!I'&4;? d,-~ ~

4u~~~J ~ ~/V e~ ~/_/h'~-d~J ~/£}~-~~~~

~ ~ ~ --bv-6L~~~ ~

~~o/ d~ 4*-7 ~~ C<- /t7~ ~_-~d /e~ ---~ dWd~J~~~ ~~ ~/ff'a! a~ ~~ ~~

~ A; kL~ 4a/-k /~~~7d4~~~'~~r~4-t'~~/~~~dL (~//r&~~ d ~A/~c/ rYU- k~~d- ~ 4~~ ~ ~~/)-V

~~~d~~7ijJ ~~

/PU-7 ~ ./J4/ ~Ld ~ J 8l-?- ,/77~~ ~dJ

~~ ~~ /u-e~~ ~~~d;~d' ~ -;;?~~~ /?n7 d~~~~~/U~~~~

~ ~-e&AU!- 41

g,,:y~uh£~· f/k /~? P#7~~~4 ~Ldu.tL ~ ~~ 4& ~ ~_

-~,~ $a/1 ~ ~~~ 4/-~4U~Jd7

/; /~ a- ~ ~ A!fe- ~/U-ce-,

~:i/PZ~ ~ ~ #d~j ~J~~-u#u- ~ ~a-/u- a. r~k,rYV ~~ .-b~~c/ &/7-?d ~jzvr~uL."~r~ c4D-d~ ~-k~~~~~J~~~f?~ ~d~ ~ ~ 4/Jn~ Y'~~ ~~ /7Pu4.~~ ~ -d~~J ~

~ ~~~4~ ~d ~~ 4~'

-~/J~/- d; .~~ ~ ~r~ ~~~~~ ~~eJ&-/~~u~~#d-d~~-7~a-7-4d ;f;: a c!a(J/VIa£ ~b;-~ ~ j4~-;~d ~dd~ --/~ 40 k ~~ &d-/~;JJ. X ~/P?~ ~

~ ~ ~~ ~- ~ ~o///h-&~~/~. ~~~~~E?0~~~a~erd~d~~~ ~~--d~ 0/7 ~~~~~ ~~4ad;ffn-./ 4~ t!~/~

t/~a-?Ad~~'~~~-~.~ ~.. P'k F~ -/~~d ~ /~ /-M-~~t!£ ~~ 4

a:- dL~~ ~ ~ ~/L~d'-d'~u-~~~J ~d'~~~~~~~d~~~~~~~~d:e-7~'

Ph 7/74-dN ~ ~4d .dw /e<a.e ~ ~

--vr~ /~~ ~~ ~-t%t-4ea/~4J~ ~ ~~~ 4~4L;/h~

~~~~aA~~~~~~~~d~~~~~_

-~~~~~~~K~~~ ~d~ ~ ~#e/~-,~-d 4-C'~7 ~-! ~ kd~~~d' ~/~~ ~~~~- ~~_

-~. #~~~~~.~~tA'4 ~~~ ~ ~ k~c:/k~~L- ~d ~J ~d ~~

(7)

~d~~ ~ P//J~>?a-d p/Z~ ~~~~lL- r-e~ ~ c?/~ ~

~~J~~d~~k&-

d~ ~ ~-7~/t:;-nz/ ~~ dU~

~d 6'1- tX~t!4~d -/~~~~p~~ ~ ~#7/l~d a/l/ld Le/U-U~./ ~

~d~~k--~~~r~ ~/V ~~~~ ~ Pt- k~~4/ d~~J ~d- & A';r~~~~~~~e~~

¥ k/- t7& ~J ~'e.4 ~ #t:/7rl-1-

~.. aTd- ~~ a ~~ # ~ L;:-

k~~/~~ ~UtK-~~tr/

/kk~ ~d ~~~ tX-~~

¥ ~~t:t~~ ed~ ~&4£e~JCL ~t?/~? ~~~~d~J ~tL

~~~~~/h~J~~~.

-4~~~ ~~~ ~~f/~~4., AJqD0J ~~ ~tt/~~~

( /Il /

~~~.~~tX-~ ~~~~_

~~~ ~~a~.. e7k ~U4f

~~~Aae~~~~~ ~ &/---er-n- ~ ~~ J~~,.j~

~ ~~~~-:;c-74- fn/£- a- ~~~ -4~-

- ~~-v-L-" e7k ~~~~ ~ ~~~d~~~~u/~~~~-6~~9~~~j1fJ0-£2~~ ~1~/ ~ ~ ~ ~~~~ ~ »rr&/ti"p ytlt/M~J ~d ~~. dk~'l-e--r~~ /h--?~ ~~elh-~

tH- a- ~~~L ~~7 ~~ ~~~.~ P .d~~~~ ~ ~~ ~ ~ ~~n--

-h~ ~~/h?~A~~~~a#d~ ~~ ~/,7~ ~-~ ~~/-/CvP;~4-U~~4b~. ~_d~~d-th~ ~L~ 4~ ~u{ ~~~ ~0~/u-?-e.

a-4/h~ ~L/~a4~ ~~~dbl~ #~.

k A?~d-~~~~ tHJ~ ~g:;-- ~~~~/7'~U!- ~~ ~d4e ~~~

~ ~ -'- - ~~~8-u--J 0/4-'?d %(lYV)~L~ aLL~£.c~ II

~ t!£H74 u/~ ~ ~ Mv~v-<:d--4~

;nk 4-h~ tH' ~~u:dJ ~~ ~ ~

~~t'c? . 7P!-~ ~~cderlr- /7?w;;J

~~d ~ ~ A~~~J Ct/Hd d'~ J{!~trN"

--d~a£ c:/ a/~L/ ~~ ~/hU'd ~ ~

~_ ~ ~ ~~tfe ~&-<!~_

-~~ • ~~ ~4-(~J ~ ~ M~~ e~ ~ ~/lH'~ ~~~.1

~/J/l~J ~ 4n#e~ ~I- ~ #~-

~~ &~~~IYY#~y ~~

~~~{l/J-~ %e- ~~ ~h:;/U~ ~(J1-~

/ff?ap /re~4 ~ ~-bJ-r~d-, h4-~~ ~ ~ ~~/P/J ~ -*!:/~~.

~ ~~ ~ &~ 7~" t9-J~~~

-1; ~ ~ ~~~J -if4A~ 04 -q~~

~ ~ a./ZAd &rt!'~ a~~ ~-/h-~J ~

(/2)

~&tY?~ ~~~ ~ ~~~~

~.d A44.«'~~" "p;?-/cW~~~d~ &'uA4~ ~

~~a/~7 //~ ~ 4-e~-~ ~

--4-k/Ud ft ~ ~/Jud ~/ 0Vv-l4.., ~d

ad a. /h? ~ 7~A//'if<:'J ~ ~~ t:'L-

~~~ ~ ~-d-e- a/~-~-f~d ~~.

f/k ~/U-?~-~..eb 6t-vt,d ea/d~ -7~~ ~~ ~~-U- ~hth~J ~eL

o:AJ a ~~ ~~~~ u-/-;nt;~j a/Z/?d ~ #t;.#d~ ~~ ~A~~ ~~~~~~~-

-~~ ~/ad-. e7~ ~ 0;/~~~~~ ~~ 4; ~ ~10~~ cfr /Jna-/~~d ~~~J a. ~ Al4A~ ~C/ ~/U:.-

-duL d~7 ~ ~ ~/~a-~~--~e-e.~a~~~~d J~~~.~ #~ ~~~ ?-/~)t/h:r"L:-:-~ 7~ /~u~ 1M! ~ u--n~-~. U~4;~.~~-{~ ~

eLd~~~ ~d ~~~cL/~

a44;dJ ~7~~~AI~ ~~~~~d-~~~~~~

d/ aJt:;~ ~ 4{; d-~~~cdj ~d;~r~~~~~.~J~. ~ ~/~~/V-~

cY ~~6??d ~ ~d ya~ ~ ~-~; ~~~~~~~~

~ ~-/~ ~~ ~~" ~7)~ ~ ~ /V-6VJ'4~ fr~.J /~~~ ~~~a/~J ~ ~'d ~~

#~A/-J~- 7~~ ~-~4~~/~~/d.-1?~~~~ a~-/~~J ~~ ~ p~~~~~ -4~7 ~~;o~~-

~d t:U~ ~~~ ~-<'~~~

~~/YYIu/~J ~ ~- ~~'rJev£~ ~~ ~ ~d~d- aMd/~ ~. ~;;;/>

~ ~.h~/Pn~/VZ</ ~ /~~ .

~~~-~~.e~~k~I~ ~ a!U~ ~/n1/uVL ~ e~ ~

~~~ ~ ~/PLI!6Uu eh-e~ ~~

fJ-7 ~~4 ~ ~ #dzd /~ ~4;" ~ffad 7k ~£;;d ~d6~Lad~ -U a ~oj ~ ~~ 4~~~ ~4~~#a-/Yn/J-nd~ ~ 7-#~ ~~~ Lud- ~ ~ dULeuU-.

~~~d~# h~tj? Ci//-e ~~

~~~ l7--7~ ~ Jh ~d:, ~~d-~-/?n~~/~~c/ ..4 4~ k~d ~r~7 /~dt5/~~/~~7 ~d-4 Z-v/ /UA- ~.q/~

~~~~~-eI~~~~d-~~£&~ "t&/ ~ /,d~ ~y, ~tJG~~ ~C/~J ~d-;zk;~~

~k~~~d&~~~~ 4AI

d-~J dd-~~~~~~~~7~~~.

$1 ~ ~~ ~-~t!'ud'e-~~//~

~ kd~ /r~~fid-~a/ IX

~~ ~./7~A14r~~ ~~cL)~ gfd-~ ~~-

,-/Pn~ ~d' ~ ~ k ~o;kd.~4 ~ ---k~&dL A-u-~ ~.ffl-

-~7~#~. 47~~d~a'~d~4~~o-Y~

~~/U-- /PU~ ~~ ~d ~-1#-4 ~ ~d~-_ JfI/~ ~k ~e;/ ~ebf~ ~u/d k/~, dl~~~ tXd~eed/~~~~~_~

~~-=eL ~ 7~ /~d- ~~:8-~~-;t¥ ~ ~ ~~~d dfJU41 I30--e-

~ ~uJ&- ~ /Md7~ #d~.4~~ ~ &tMf~~ P4~ ~

)'~~~ ~ ~~. c& ~d-U1~)~dL ~~~~ ~d ~J~ ~~-~~d 7 ;dw ~ $/Ud ~~/}-ueL d,#~

~~~J ~~4-4~d&{}f~

~ #~ ~~tiL ~,~._cL dU/~ ~ 6t'- ~ru/UeL ~~

~~/U-'la/~J 4<J ~ ~.ffl~~--e.L

tJ(.e;~~~d~ ~ ~ /d~4~ ~~-~~ a' 6L ~~&(eL4~~~~/h4~J ~O/ /U ~~~4~

~~ii:u;:;/~c:/Rz- ~ ~~~ t2r ~)~-~~~di;-~~-_.J~J ~ $-P~ fl1z#u.. /h?7 k~bH~..ed 4;" Af~ ~ ~-/~~ .a-<-

~avzA~ ~~ ~~~ a'~P& 4-~~~~~ ~//~~~~.

d~ ~ ~ /JtAA- ~b7-e~ ~ ~

~ ..~~:"' ~~~~ ~d ~ z/zk..d~~~/~~. 4~d~jI/H;~ ~~7 ~~ ~~,4-

~f7-U/~J ~~~'~7~~ J'7~ ~d ~d,d ~~-

( /j')

~~~~d~-~~~-~. ~~#/~~/7~~ ~ ~~~./ ~/Jn~ EhAM -d'L~/dY~. x.~ a/~ /J'n",/" h/~ ~A~ ~~ -hd-/~aLj ~ I/tr,$zr.rJ /7U';j ~ ~ /~~ C/d~/;;d.

~~ 0~~ A4~d ~ d~7()l/l/tidLd . ~~~ d ~~ ku-

~4r77!'~ a-ud k1-vt7~4a?~--~ :/ 4;;~~~ t/Vvld ~~~ aLu-~ ~dMe£- A4-- ~u{ ~ ~ /Jrf-ue4

h-~ ~ ~ jJ~~ ~~ ~Jcu1-L.

c1/-lj ~,vdu~~ d~~ ~-d-/~~ ~ d- ~ d-uM-eoS ~~

~ #,,~~/.-Vu~j d-M ~ ~---d~d L;;-~d ~d1~~ ~~-k~~ ~ ~~ ~ A!/U~c/~.

U~ /~~ -~ 7~aH~a:~d-/~~~~~?4~

~Af'~/~&.-J ~ ~d/bn~, ~

~.x/~ )~~~ ~ ?~. ~d-d~~~~ 4 fa.-ua~~ xx. Ih'XkXr/k

-/d~d ? ~d- evu-d #'~~ ~ ~4k~. ~LH~ -e. ~,f~ ~/

~~ ~ ~ ~ t;~£ u/ 4~dU-/,ffWL. k Jh ~~J ~~

4Jf ~~d4~ ~ --£y-Ub~~d; ~~_-~ ~ J./ ~ arU£ ~~ d",~/1uAA~~ O'/H!- yu~ ~ ~--id 0/vI~

/~~ d:;~ /~. J/h- ~~a/~ee~ -d/~~ ~j~~/.

';If ~ff/e:7 U'~ x~ ~d- A/dd--JhM /I.r ~ dd/a4U /'7. d-~4-v.-n.~~~ ~~8Lkr/~e~ ~~eLa! ~ ~~ d;-

~ad~~/~~~~d~~J ~ ~~& ~4-f?~.~~~~~)~~~~~

(// )

cH- ~~ ~~'" ~ ~ Afd~dk~~ ~f?/Le. ~~. A/X-r t7~~~

~ ~ /tlTPd' ~ ~ ~ '2{""" 4r '1///(;/#

)'~ 4u- A'~ .A4~& --<'~~~ ~~~r~J~~~~~dd~. $4~~~~

-/U~ ~ d£/h~--7~'P?/L~::?d2~~a/~j!/44-id' .d# ~ k-y L;;;;/H"d ~&4~ ~d~-d/~ r d-t!7~&L --//~40U/--0. ~ ~ ~ u d:? ~.d 4t?d~/~~-/ k o-zt/~d~/~/~M~~ tJ-'fr ~ /U-1'afid ~1.-7-~

~~M~ 1YY~~c/, ~L~u/dLe/~.4~.d/UAaLC' ~~ ~ 6-y

~ ~~ /? Adf~~ 7;;?~13Ly~ ~ xx,r 1f~~Clf!fj,.jhr ~~~ fi,?"

~. /M,.&-U- ~ ~ IH'~ ~~,

~~ ~ /?VUd ~ ~ CL+e~

k~U~0 ~~~a./- ea« ~4dd --tk

r~ .dd- db/dZud- ~ ~A- ~?t74~k udal. ~~ ~~~cvv-e ~M.Af-Ld ~'U'~J ~ea(!, ~a4 ~

~d7d £;; 4k u.Ud ~ ~~J:J:~~ d~- /' 4'~~ 7~ dU~d4e.A!'~~ :/'..4ad .-U ~d ~ iU/.£4-Edd~dr-~ -if4f~~~~f1-h ~H

~e-J ~ ~ad'a~ ~ t?-i£ u/~--).bU~ -kav-t' ~ uA-Ld ~ ~~.

~M'~ P aMPrC-d & ~ uLe-~

#~~ ~d ~~ 7/M--/M /J'U~

/JL ~ t!~~~ I h~ ~~ 444~

I?U ~~~d~. g~~;;/~~d ~ad¥/ed~~ ~~~ &A/tU~~~ ~pr!d~ ~ -4~~ ~ /UALed ~ ~/V-t%/n~.

S4-d-: .dn, ~ e~ ~ ~d~-

~~~~/~a~4~_-~) ~ /J-teeJ .-d/iZ& hao(, ~ae/Un'/

•

Lu/-~ ~ #~~L~J FMa~~d /7~eY~~ eLr~:J ~~FU j/ tJi~~ /~ ~~J ~

~; /~-' ~~ t:/ ~~J

~~ -d4A.-d- ~.fd ~ ~~~ ~rULd Le ~~c:£. ~ ~~ _

_k~~J ?~d- t!aH!- ~d ~ ~A; ~~-~/~-~~'

p,' / /7~ a/~J e:U~ d /H'U41Yk c/~~

~t?L~~~~~~

-4~d-~~~~~~~£/~4;- ~ ~ /~(- ~ ~ ~CL

~~ e/~ ~ ~~J?d, ffe:r--o~

~ ~d~~ 0VVtU£ -ddA/WH}~"'/7

~~d~~ ~ &;j~~ Ct.d

}J&--d4dL ---_-----