LINKLinking Excellence in Biomedical knowledge and Computational Intelligence Research for personalized management of CVD within PHC

FOZ DO IGUAÇU, 17TH OCTOBER 2016A. MARTÍNEZ-ROMERO

V. TRAVER

ANALYSIS OF EU – BRAZIL COOPERATION OPPORTUNITIES ON TELEHEALTH

The EU CONTEXT

The LINK Project

Analysis of opportunities

Big OPPORTUNITY TO STRENGTHEN COOPERATIONSHIP

BETWEEN BRAZIL AND EU

0 25 65 years

Illn

ess

Pre

-Illness

Wellness

Crowd Achievable Health

Crowd Actual Health Outcomes

Death

60-80% Preventable

Modern Crowd health landscape

Age

The silver economy

The silver economy

The silver economy

The silver economy

The silver economy

Prevention, screening

& early diagnosis

Care & Cure Active ageing &

independent living

•Health literacy, patient

empowerment, ethics and

adherence

•Personal health

management

•Prevention, early

diagnosis of functional

and cognitive decline

•Guidelines for care,

workforce

(multimorbidity,

polypharmacy, frailty

and collaborative care)

•Multimorbidity and R&D

•Capacity building and

replicability of successful

integrated care systems

•Assisted daily living for

older people with

cognitive impairment

•Flexible and

interoperable ICT

solutions for active and

independent living

•Innovation improving

social inclusion of older

people

Vision / Foundation

•Focus on holistic and multidisciplinary approach

•Development of dynamic and sustainable care

systems of tomorrow

•New paradigm of ageing

•Innovation in service of the elderly people

•Regulatory and standardisation conditions

•Effective funding

•Evidence base, reference examples, repository for age-friendly

innovation

•Marketplace to facilitate cooperation among various stakeholders

Horizontal issues

European Innovation Partnership – Active and Healthy Ageing

Implementation

Participation in the EIP-AHA initiative can happenthrough:

• Commitment. Interested in the deployment of specificactions

• Reference sites. Places where differents specificaction are already deployed in a integrated approach.

• Marketplace. Innovative ideas.

• Research and innovation action

• Innovation action

• Coordination and support action

• SME-instrument; incl. fast track to innovation

• Pre-commercial procurement co-fund actions

• Public procurement of innovative solutions

• ERA-Net co-fund

• Joint programming

• …

Horizon 2020

Societal Challenges - ICT

1. Health, demographic change and wellbeing

2. Food security, sustainable agriculture, and forestry, marine, maritime and inland water research, and the bioeconomy

3. Secure, clean and efficient energy

4. Smart, green and integrated transport

5. Climate action, environment, resource efficiency and rawmaterials

6. Europe in a changing world – inclusive, innovative and reflective societies

7. Secure societies – protecting freedom and security of Europe and its citizens

1.1 Understanding health, well-being and disease

1.2. Preventing disease

1.3 Treating and managing diseases

1.4 Active ageing and self-management of health

1.5 Methods and data

1.6 Health care provision and integrated care

Horizon 2020 – Societal Challenge 1

The silver economy

The LINK project

The LINK ConsortiumLinking Excellence in Biomedical knowledge and Computational Intelligence Research for personalized management of CVD within PHC

3 partners

3 countries

Objectives

Objective 1: To define a research agenda Establishment of a research forum for intelligent algorithms

for PHC in CVD management. Industry: Philips, IntelliCare, VTT, Medtronic, TSB Academic: California University, Georgia Tech, Uni. Zagreb, Professional Societies & Professionals: IFMBE, IEEE-EMBS, European

Cardiology Society, Portuguese Cardiology Society, HL7 Foudation, ISfTeH, several hospitals

Decision Makers: Portuguese Health Ministry, Croatian Health Ministry

Patients: European Patient Forum, Patients like me

Contact with fundamental stakeholders in the field to help identifying key gaps and barriers

Definition of a research agenda for intelligent algorithms for PHC in CVD management.

Objectives

Objective 2: To deepen the link between research institutions in a sustainable way

Objective 3: To enhance S&T excellence in intelligent algorithms for PHC for CVD management

Objective 4: To increase international impact and recognition

Objective 5: To enhance Innovation and Inclusion

Research Innovation Forum (RIF)

Composed by a set of experts from different countries (US, Italy, Spain, Portugal, Belgium, etc.) and different profiles (clinician, decision maker, multinational company, researcher, entrepreneur, patients ’associations).

Up to now, 22 members have accepted to be part of the RIF.

Focus

Analysis of the State of the Art (SoA) and future trends in pHealth solutions for integrated CVD management

Identification of open research problems and opportunities in algorithms for pHealth solutions for integrated CVD management to support these concepts

Identification of opportunities for Concept development in pHealth solutions for integrated CVD management

Methodology

Delphi study - Iterative process

Statements from internal analysis and discussion withexperts

3 major focus Analysis of the State of the Art (SoA) and future trends in

pHealth solutions for integrated CVD management (13)

Identification of open research problems and opportunities in algorithms for pHealth solutions for integrated CVD management to support these concepts (11)

Identification of opportunities for Concept development in pHealth solutions for integrated CVD management (5)

Analysis of the SoA and future trends

3. New algorithms are needed to infer knowledge from data in order to practice evidence-based medicine (37)

4. Quality of data is a dimension not to be missed when researchers are inferring knowledge from heterogeneous databases (26)

1. Success of PHC for CVD is fully dependent on data availability (20)

7. It is crucial to have real time telemonitoring to provide PHC services, being possible thanks to mobile services(16)

Analysis of the SoA and future trends

There a set of statements (2, 6, 10, 11, 12) of interest for half of the experts. These middle priority statements are the ones focused on robots, pervasive telemonitoring, legal issues, ICT based clinical management and creation of individualized behavioural models.

Statements 5 and 13 about data infrastructure and patient models were the less select/prioritized by the experts. Statements 8 and 9 about ethical issues and feature selection were also not selected by the majority of experts.

Identification of open research problems and opportunities in algorithms for pHealth solutions

TOP PRIORITY QUESTIONS

11. How to support the integration, discovery and use of clinical knowledge in daily clinical practice? (27)

10. How to personalize models for diagnosis and prognosis? (27)

5. Which indicators are the key ones for CVD risk assessment? (26)

6. What are the best strategies to combine data and knowledge driven learning and modelling approaches? (19)

Identification of open research problems and opportunities in algorithms for pHealth solutions

MID PRIORITY QUESTIONS

1. How can different sources of information be integrated, especially on large databases? (15)

8. How can the assessment of cardiovascular functions and status using wearable technologiescan be improved? (14)

9. How can multi modal and multi scale data fusion for robust biosignal processing be improved? (12)

3. How will mobile technologies improve continuous monitoring? (10)

Opportunities for concept developmentof pHealth solutions

Brazil and H2020

Brazil in H2020

ALL calls are open to international and more specifically Brazilian participation. For more details on funding of applicants from non-EU countries, click here.

Key areas of EU-Brazil Cooperation: Sustainable Agriculture, Bioeconomy, Food security, Nutrition, Energy, Marine Science, Information and Communication Technology (ICT), Nanotechnology.

Brazil in H2020

Emerging Economies no longer eligible to receive automatic funding under H2020

How can Brazil participate in this framework?

Coordinated Calls –i.e.– in Biofuels and ICT

Structuring cofinancing mechanisms to cover thecosts of Brazilian participants within internationalconsortia together with the EU

Brazil in H2020

In December 2014 CONFAP and the Delegation of the EU in Brazil sign a “Letter of Intent” to promote Brazilian participation within Horizon 2020

Currently almost all State Funding Agencies (FAPs) in Brazil which are part of CONFAP have signed the Accession to the Letter of Intent

Some FAPs have chosen/can choose to sign a similar letter directly with the EU Delegation

Existing local co-funding mechanisms in Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo - FAPESP

Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina- FAPESC

Fundação de Amparo à Pesquisa do Estado de Goiás - FAPEG

Fundação de Amparo à Pesquisa do Estado de Minas Gerais -FAPEMIG

Fundação de amparo à Pesquisa do Distrito Federal - FAPDF

Fundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Estado do Paraná – FAPPR

Fundação de Amparo à Pesquisa e Inovação de Espírito Santo

Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa - CONFAP

Brazil in H2020

CONFAP is assisting its FAPs for fine-tuning, finalizing and launching their own Guidelines which define the implementation of the Letter of Intent

What are the Guidelines? The Guidelines indicate the operational framework on how

each FAP shall support the participation of its researchers/participants within projects funded under Horizon 2020

In practice, the Guidelines can be considered like a parallel call for the submission of research and innovation proposals in coordination with Horizon 2020

Each FAP shall adjust them to their own needs, funding capacities, research & innovation priorities, funding lines

Brazil in H2020

Projects positively evaluated by the FAP shall be only approved if also approved under H2020

www.confap.org.br

Specific opportunities

Topic MSCA-ITN-EID European Industrial Doctorates , MSCA-ITN-EJD EuropeanJoint Doctorates , MSCA-ITN-ETN European Training Networks

Summary: The Innovative Training Networks (ITN) aim to train a new generation of creative, entrepreneurial and innovative early-stage researchers, able to face current and future challenges and to convert knowledge and ideas into products and services for economic and social benefit. ITN will raise excellence and structure research and doctoral training, extending the traditional academic research training setting, incorporating the elements of Open Science and equipping researchers with the right combination of research-related and transferable competences. It will provide enhanced career perspectives in both the academic and non-academic sectors through international, interdisciplinary and intersectoral mobility combined with an innovation-oriented mind-set.

Deadline 10th January 2017

URL https://ec.europa.eu/research/participants/portal/desktop/en/opportunities/h2020/topics/msca-itn-2017.html

Subprogram MARIE-SKLODOWSKA-CURIE ACTIONS (MSCA)

Specific opportunities

Topic EU-Brazil Joint Call EUB-01-2017 Cloud Computing

Summary - Cloud computing is now an established global paradigm for the delivery of IT services in all sectors of the digital economy. However, further enhancements are still required in critical aspects of cloud computing, including enhanced security and privacy; trustworthy clouds; resource pooling; data management and traceability; virtualization; and hybrid systems. Support towards intercontinental experimentation on cloud infrastructures and services are necessary as well, especially in the context of EU-Brazil cooperation

Deadline 14 March 2017

URL https://ec.europa.eu/research/participants/portal/desktop/en/opportunities/h2020/topics/2079-eub-01-2017.html

Subprogram ICT

Specific opportunities

Topic EU-Brazil Joint Call EUB-02-2017 IoT Pilots

Summary - In order to make use of the rich potential of the Internet of Things (IoT) in real-world scenarios, technologies and tools developed so far need to be demonstrated in controlled environments with the ultimate goal of validation. Given the specific nature of this Call, widely replicable pilots are targeted in view of solving specific societal challenges, in the context of EU-Brazil cooperation. Environmental monitoring

Utilities: smart water management

Utilities: energy management at home and in buildings52

Smart assisted living and wellbeing

Smart manufacturing: customisation

Deadline 14 March 2017

URL http://ec.europa.eu/research/participants/portal4/desktop/en/opportunities/h2020/topics/2080-eub-02-2017.html

Subprogram ICT

Specific opportunities

Topic SC1-PM-03-2017 Diagnostic characterisation of rare diseases

Summary - The aim of this research should be to apply genomics and/or other –omics and/or other high-throughput approaches for the molecular characterisation of rare diseases in view of developing molecular diagnoses for a large number of undiagnosed rare diseases. Undiagnosed rare diseases may range from a group of unnamed disorders with common characteristics to a phenotypically well described disease or group of diseases with an unknown molecular basis.

The proposal should enable and foster scientific exchange between stakeholders from countries and regions with different practices and strategies of rare disease diagnostics.

Deadline 11 April 2017

URL http://ec.europa.eu/research/participants/portal/desktop/en/opportunities/h2020/topics/sc1-pm-03-2017.html

Subprogram HEALTH, DEMOGRAPHIC CHANGE, AND WELL-BEING

Specific opportunities

Topic SC1-PM-15-2017 Personalised coaching for well-being and care of people as they age

Summary - This topic aims at developing a proof of concept of radically new solutions for a personalised "virtual coach", building upon intelligent ICT environments, access to relevant physiological and behavioural data, new forms of accessible interaction based on tangible user interaction concepts, open platforms and emotional computing.

The "coach" should provide personalised advice, guidance and follow-up for key age related issues in daily life which impact the person's ability to remain active and independent, for example diet, physical activity, risk avoidance, preventive measures, lifestyle and activity management, leisure, social participation and overall wellness.

Deadline 31 January 2017

URL http://ec.europa.eu/research/participants/portal/desktop/en/opportunities/h2020/topics/sc1-pm-15-2017.html

Subprogram HEALTH, DEMOGRAPHIC CHANGE, AND WELL-BEING

Specific EU country- Brazil opportunities

Sweden – VINNOVA

https://goo.gl/ZKm4qG

SPAIN (CDTI) – BRAZIL (FINEP)

Bilateral joint call for proposals to fund R&D in collaboration between Spanish and Brazilian companies

Portugal, Spain, Brazil – IBEROEKA

CYTED. Instrument to support business technological cooperation in Latin America

Brazil in H2020

EUROAXESS Brasil is a networking portal that provides information on funding for researchers in Europe and Brazil (information only available in English).

Aporta It is a EU portal with information on national research and innovation programs in Brazil and helps find partners for joint projects.

Ciencias sin fronteras is a financing program for exchange and international mobility, managed by CNPq

CAPES has mobility programs for PhD students and postdocs with Spain

More information

INCOBRA Projecthttps://www.incobra.eu/

INCOBRA is an EU funded project started on 01/02/2016 aimed at encouraging bilateral cooperation between R&I actors in Brazil and the European Union, fostering collaboration and implementing activities agreed within the BR-EU Policy Dialogue on Science, Technology and Innovation. Over the next 36 months, various activities will take place to identify main trends, help with coordination of funding opportunities, matchmaking of companies and institutions, to network and make alliances, and to support alignment of EU-BR agendas.

Brazil in H2020

Delegation of the European Union to Brazil: http://eeas.europa.eu/delegations/brazil/index_pt.htm

Questions may be addressed to the Research & Innovation Section of the EU Delegation to Brazil: DELEGATION-BRAZIL-CIENCIA@eeas.europa.eu

The network of National Contact Points (NCPs) is the main source of guidance, practical information and assistance on all aspects of participation in Horizon 2020. The list of National Contact Points can be found in the Participant Portal here.

The Brazilian NCP Coordinator for Horizon 2020 is: Prof. Moacyr Martucci Junior University of São Paulo - Polytechnic School Avenida Professor Luciano Galberto, travessa 3, 158, Sala C2-49 05508-900, Butanta, BrazilTel: +55 11 3091-5626, http://www.pcs.usp.br

Resources and useful links

HEIDI – health indicatorshttp://ec.europa.eu/health/indicators/indicators/index_en.htm

Approved H2020 Workprogramme 2016-17 http://goo.gl/aKh2uG

EIP-AHA website http://ec.europa.eu/research/innovation-union/index_en.cfm?section=active-healthy-ageing

Scaling up strategy https://goo.gl/ElzbgE

LINK Project https://www.linkresearch.eu/

LINKLinking Excellence in Biomedical knowledge and Computational Intelligence Research for personalized management of CVD within PHC

ANALYSIS OF EU – BRAZIL COOPERATION OPPORTUNITIES ON TELEHEALTH

FOZ DO IGUAÇU, 17TH OCTOBER 2016

Vicente Traver vtraver@itaca.upv.es Twitter, Skype vtraver

Presentation available at www.slideshare.net/vtraver