animal and plant viruses
DESCRIPTION
Animal and Plant viruses. Plate Culture of Animal Viruses. Figure 6.33. Figure 6.20. Papillomavirus (DNA) Life Cycle. Figure 6.22. Picornavirus (RNA) Life Cycle. Figure 6.23. Figure 11.15. The capsid is fundamentally icosahedral. - Composed of three external proteins (VP1–3) - PowerPoint PPT PresentationTRANSCRIPT
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Animal and Plant viruses
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Plate Culture of Animal Viruses
Figure 6.33
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Figure 6.20
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Papillomavirus (DNA) Life Cycle
Figure 6.22
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Picornavirus (RNA) Life Cycle
Figure 6.23
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Figure 11.15
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• The capsid is fundamentally icosahedral. • - Composed of three external proteins (VP1–3)• - VP4 protein subunits coat the interior and
help package the (+) strand RNA genome.
Poliovirus Structure
Figure 11.11B
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• The poliovirus binds to poliovirus receptor (PVR) through its VP2 and VP3 subunits.
• - A conformational change in VP1 allows insertion of the genome into the cytoplasm.
Figure 11.12
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• In the cytoplasm, the RNA is translated to make three large precursor peptides: P1–3.
• - All three peptides are eventually cleaved by proteases to generate 11 proteins.
Poliovirus Replication
Figure 11.13A
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• The flu virus has no geometric capsid. • RNA genome is loosely contained by a shell of matrix
proteins.
Influenza Virus Structure
Figure 11.16
RNA segments are coated with nucleocapsid proteins (NPs).
Two major envelope proteins:- Neuraminidase (NA)- Hemagglutinin (HA)
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Influenza virus: note envelope
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Figure 11.17
The Genome of Influenza A Virus
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• The key advantage of a segmented genome is that it facilitates recombination between two strains coinfecting the same cell.
• - Instant new strain can evade the immune system.
Figure 11.18B
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• Animation: Influenza Virus Entry into a Cell
Click box to launch animation
Influenza Virus Entry
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Figure 11.21
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• Animation: Influenza Virus Replication
Click box to launch animation
Influenza Virus Replication
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• An icosahedral capsid houses the dsDNA genome.
Herpes Simplex Virus Structure
Capsid is surrounded by a protein tegument, which is contained within an envelope with spike proteins.
Figure 11.31A
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Figure 11.32
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• Animation: Herpes Virus Replication
Click box to launch animation
Herpes Virus Replication
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• Within a plant, the thick cell walls prevent a lytic burst or budding out of virions.
• - Instead, plant viruses are transmitted to uninfected cells by plasmodesmata.
Figure 6.26
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Fig. 19-11
CapMTH
Stopcodon
RNP MP CP
tRNA-likestructure
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A viroid
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Figure 6-6 Viroids: infective RNA.
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Figure 6-7 Prion disease.