announcements

12
Announcements • Ch. 8 Part 2 Homework due today • Ch. 8 Part 3 Homework due Friday • Online quiz due at midnight TONIGHT • Lab tomorrow at 8 AM • Review Session: Tuesday March 4 th at 9 AM and 10 AM…Bring muddiest points

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Announcements. Ch. 8 Part 2 Homework due today Ch. 8 Part 3 Homework due Friday Online quiz due at midnight TONIGHT Lab tomorrow at 8 AM Review Session: Tuesday March 4 th at 9 AM and 10 AM…Bring muddiest points. Bacterial Genetics Chapter 8 Part 3. Recap (2 Minutes). - PowerPoint PPT Presentation

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Page 1: Announcements

Announcements

• Ch. 8 Part 2 Homework due today• Ch. 8 Part 3 Homework due Friday• Online quiz due at midnight TONIGHT• Lab tomorrow at 8 AM• Review Session: Tuesday March 4th at 9 AM

and 10 AM…Bring muddiest points

Page 2: Announcements

Bacterial GeneticsChapter 8 Part 3

Page 3: Announcements

Recap (2 Minutes)

What are the mechanisms by which bacteria can acquire new genes?

Answer:DNA-mediated transformation

TransductionConjugation

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Revisiting Plasmids• Common to bacteria• Double stranded DNA• They have ori• Do not code information

critical to a cell’s life• Do provide an advantage

for certain environments• Vary in amount of genes

they carry: few to many• Narrow host range• Transferred by

conjugation• Resistance plasmid-

encode resistance to many antibiotics

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Horizontal Gene Transfer: Chromosome Transfer

• Less common than plasmid transfer• Involves Hfr cells: High frequency

recombination• The plasmid integrates into the chromosome• So, part of the chromosome ends up getting

transferred to the F- cell

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Horizontal Gene Transfer: Chromosome Transfer-Formation of Hfr Cell

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Chromosome Transfer

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Revisiting Transposons

• They can disrupt genes• They can also transfer genes from one

bacteria to another• 2 types: insertion sequence and composite

sequence

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IS vs. Composite Transposons

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The Role of Transposons In Antibiotic Resistance