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ANU College of Medicine, Biology & Environment THE JOHN CURTIN SCHOOL OF MEDICAL RESEARCH Annual Review 2014

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Page 1: Annual Review 2014 - John Curtin School of Medical Researchjcsmr.anu.edu.au/files/2014_final_report.pdf · Dr narci teoh (canberra Hospital) ... Annual Review 2014 9 ... Professor

ANU College of Medicine, Biology & Environment

T h E j o h N C U r T i N s C h o o l o f M E d i C A l r E s E A r C h

Annual Review 2014

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Annual Review 2014 1

contents

From the Director 3

Organisation Chart 4

Committees 5

Community 7

Launch of the national centre for Indigenous Genomics 8

the Judith Whitworth Fellowship 9

the 2nd Annual Dinner of the John curtin Medical Research Foundation 10

Launch of the centre for Personalised Immunology 11

Welcome to the centenary chair in cancer Research 12

the sarah Grace sarcoma Foundation 13

the John James Foundation tony Ayers Prize 14

open Day 15

the JcsMR Director’s christmas Morning tea 16

our community 17

Staff and Student Achievements 21

Graduates 22

Prizes and Awards 23

Visitors and Collaborators 29

Visitors 30

collaborators 32

Staff and Student Lists 45

Department of Genome Biology 46

Department of Immunology 48

eccles Institute of neuroscience 50

Department of Molecular Bioscience 52

Department of Pathogens and Immunity 54

Australian Phenomics Facility 55

school Administration 56

school services 56

the AcRF Biomolecular Resource Facility 57

Genome Discovery Unit

Imaging and cytometry Facility 57

students 58

Publications, Presentations and Community Outreach 61

Publications 62

staff Presentations 68

student Presentations 73

community outreach 77

Support to JCSMR 85

Grants 86

Financial overview 90

Donors 91

Report from the John curtin Medical Research Foundation 92

sponsors 93

Annual Review 2014the John curtin school of Medical Research

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2 the John curtin school of Medical Research

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Annual Review 2014 3

It is our great pleasure to share the achievements and activities

of the John curtin school of Medical Research for 2014. A

companion volume, Research Highlights, describing some of our

current research projects, will be posted in December 2015.

I joined the school as Director in october 2014, and I would like

to thank my predecessor, Professor chris Parish, for stepping

into the role of Director in April 2013, and for his leadership of the

school. In 2014, chris was honoured with the title Act citizen of

the Year, and received the chancellor’s Award for Distinguished

contribution to the University. He is to be congratulated for these

stellar achievements, and thanked by all of us for his enduring

dedication to JcsMR.

Many other JcsMR staff and students received honours and

awards during 2014, recognizing the commitment they bring to

their research and teaching practices. In particular I would like

to congratulate Professor carola Vinuesa, who was awarded

the inaugural csL Young Florey Medal for her research in

the immune system and the production of disease fighting

antibodies, and Professor thomas Preiss on the award of the

Julian Wells Medal at the Lorne Genome conference.

JcsMR saw a number of new initiatives come to realization

in 2014. In February we launched the national centre for

Indigenous Genomics, which aims to establish a national

resource, under Indigenous governance, for appropriate and

respectful genetic and genomic research that will benefit

Indigenous Australians, and in April, in conjunction with World

Day of Immunology, we launched the centre for Personalized

Immunology, which aims to help people with immune diseases

by discovering individual genetic variations with the ultimate goal

of targeting treatments more effectively.

the JcsMR Gender equity committee successfully brought

about the establishment and award of the inaugural Judith

Whitworth Fellowship in 2014. this Fellowship, named in honour

of previous JcsMR Director Professor Judith Whitworth, and

supported by JcsMR and the John curtin Medical Research

Foundation has been established to support the return to work

of a young scientist who has experienced a break in their

research career due to maternity or parental leave. We are very

proud of this initiative, and trust that it will allow recipients to re-

establish scientific projects, strengthen track record and regain

national and international competitiveness when applying for

independent external research funding.

I hope that you will enjoy reading about the recent successes

of the school, and look forward to presenting the companion

Research Highlights.

Professor Simon Foote FFSc (RCPA), FAHMS, FTSEDirector, the John curtin school of Medical Researchthe Australian national University

FRoM tHe DIRectoR

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oRGAnIsAtIon cHARt

ANU College of Medicine, Biology and Environment

The John Curtin School of Medical Research 2014

DEPARTMENTS

Immunology The Eccles Institute of

Neuroscience

Pathogens& Immunity

ADMINISTRATION

School Manager Director’s OfficeEducationOutreach &Communications

SERVICES AND SUPPORT

ACRFBiomolecular

ResourceFacility

AustralianPhenomics

Facility

Operations Imaging &Cytometry

Facility

TechnicalServices

WorkplaceHealth &Safety

Director Professor Chris Parish (until October)Professor Simon Foote (from October)

Deputy Director Professor John Bekkers

Professor David

Tremethick

Professor Chris

Goodnow

Professor GregStuart

Professor Carola

Vinuesa

Professor Angela Dulhunty

Mr Matthew Cousins Dr Madeleine Nicol Dr Anna Cowan Ms Laura Vitler(until October)

Mrs Ceri Flowers(from October)

Ms StephaniePalmer

Dr Mark Hayes(until November)

Mr David Mann

(from November)

Dr SteveWinslade

Mr DenisCoombes

Ms CathyGillespie

Mr DenisCoombes

MolecularBioscience

GenomeBiology

ANU College of Medicine, Biology and Environment

The John Curtin School of Medical Research 2014

DEPARTMENTS

Immunology The Eccles Institute of

Neuroscience

Pathogens& Immunity

ADMINISTRATION

School Manager Director’s OfficeEducationOutreach &Communications

SERVICES AND SUPPORT

ACRFBiomolecular

ResourceFacility

AustralianPhenomics

Facility

Operations Imaging &Cytometry

Facility

TechnicalServices

WorkplaceHealth &Safety

Director Professor Chris Parish (until October) Professor Simon Foote (from October)Deputy Director Professor John Bekkers

Professor David

Tremethick

Professor Chris

Goodnow

Professor GregStuart

Professor Carola

Vinuesa

Professor Angela Dulhunty

Mr Matthew Cousins Dr Madeleine Nicol Dr Anna Cowan Ms Laura Vitler(until October)

Mrs Ceri Flowers(from October)

Ms StephaniePalmer

Dr Mark Hayes(until November)

Mr David Mann

(from November)

Dr SteveWinslade

Mr DenisCoombes

Ms CathyGillespie

Mr DenisCoombes

MolecularBioscience

GenomeBiology

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Annual Review 2014 5

Executive CommitteeProfessor John Bekkers

Mr Matthew cousins

Dr Anna cowan (until october)

Professor Angela Dulhunty (until october)

Professor simon Foote (from october)

Professor chris Goodnow (until october)

Dr claudio Mastronardi (from october)

Dr Madeleine nicol (until october)

Professor chris Parish (until october)

Professor Greg stuart

Professor David tremethick

Professor carola Vinuesa

External Relations Committee (until October)Professor John Bekkers (chair) (from March)

Mr Matthew cousins (from February)

Dr Anna cowan Dr Anselm enders

Dr Riccardo natoli Dr Madeleine nicol

Professor chris Parish (chair) (until February) Professor thomas Preiss

Group Leaders Forum (until October)Professor carola Vinuesa (chair)

All Group Leaders and Laboratory Leaders belong to the Group Leaders Forum, which meets monthly to discuss matters of importance relating to JcsMR

Education CommitteeAssociate Professor Ehsan Arabzadeh

Professor John Bekkers

Dr Anneke Blackburn

Dr Anna cowan (chair)

Professor simon easteal

Miss Preethi eldi

Professor chris Parish

Mr Roy Ramiscal

Operations Committee (until October)Dr Frank Brink (from May)

Mr Denis coombes

Mr Matthew cousins

Dr Vincent Daria (from February)

Professor Angela Dulhunty (chair)

Dr suzanne Fowler

Ms cathy Gillespie

Dr Mark Hayes

Dr Yalin Liao (from March)

Ms stephanie Palmer

Dr charani Ranasinghe

Ms Michelle townsend

Mr Dennis Vukoja

Mrs esmee Weil

Safety CommitteeProfessor Philip Board (chair) (until August)

Ms Megan clydesdale

Mr Mick Devoy

Dr Renae Domaschenz

Dr Julia ellyard

Dr sonya Glasson (until June)

Dr Mark Hayes (from July)

Dr Peter Milburn

Ms suzy Pace

Dr Krisztina Valter (chair) (from september)

Animal Users CommitteeAssociate Professor Ruth Arkell (RsB)

Dr Anneke Blackburn

Mr Anthony Barker (ex officio) (from october)

Professor Philip Board

Ms Katrina Bowditch (ex officio)

Mr Ken chau (ex officio)

Dr Lucy coupland

Professor Angela Dulhunty

Dr suzanne Fowler (ex officio)

Professor caryl Hill

Associate Professor Guna Karupiah

Professor Klaus Matthaei

Dr Riccardo natoli

Dr Ian Parish

Dr charani Ranasinghe

Dr charmaine simeonovic

Associate Professor christian stricker (chair)

Dr narci teoh (canberra Hospital)

Workshop Committee (until October)Mr Denis coombes

Professor Angela Dulhunty (chair)

Professor caryl Hill

Ms Michelle townsend

Gender Equity CommitteeAssociate Professor ehsan Arabzadeh

Dr Anne Bruestle (from november)

Associate Professor Ian cockburn

Dr Lucy coupland

Dr Julia ellyard (chair)

Ms Mary-Anne Jack (until october)

Dr Rebecca Haddock

Associate Professor Brett Lidbury

Dr Lisa Miosge

Dr Madeleine nicol

Dr Ian Parish

Dr charani Ranasinghe (until october)

Ms Monika srivastava

Dr Rebecca sweet

Professor carola Vinuesa

coMMIttees

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Annual Review 2014 7

CommunityLaunch of the national centre for Indigenous Genomics

the Judith Whitworth Fellowship

the 2nd Annual Dinner of the John curtin Medical Research Foundation

Launch of the centre for Personalised Immunology

Welcome to the centenary chair in cancer Research

the sarah Grace sarcoma Foundation

the John James Foundation tony Ayers Prize

open Day

the JcsMR Director’s christmas Morning tea

our community

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LAUncH oF tHe nAtIonAL centRe FoR InDIGenoUs GenoMIcs

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A new national centre for research into Indigenous health will help close the gap on Indigenous health and life expectancy, with the launch of the national centre for Indigenous Genomics in February 2014 at JcsMR.

the national centre for Indigenous Genomics (ncIG) aims to establish a national resource, under Indigenous governance, for appropriate and respectful genetic and genomic research that will benefit Indigenous Australians.

the inaugural nGIc Governance Board is chaired by Aboriginal and torres strait Islander social Justice commissioner Mr Mick Gooda.

1. inaugural Governance Board of the National Centre for indigenous Genomics (front) ANU dVC (research) Professor Margaret harding, Board Chair Mr Mick Gooda, dr Misty jenkins (back) Professor Mick dodson, dr Emma Kowal, Professor simon Easteal, Professor don Chalmers with dr Cressida fforde (2nd from the right). Absent: Professor ian Anderson 2. Mr Mick Gooda3. Professor Mick dodson, dr Misty jenkins, Ms Anne Evers, Ms Pip deveson and Mr Mick Gooda4. NCiG director Professor simon Easteal

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Annual Review 2014 9

the Judith Whitworth Fellowship for Gender equity in science was launched at JcsMR in April. the inaugural Fellowship was awarded to Dr Julia ellyard in november.

the Fellowship has been established to support a young scientist who has experienced a break in their research career due to maternity or parental leave and will provide up to two years of salary and research support. It is envisaged that this will allow the recipient to re-establish scientific projects, strengthen track record and regain national and international competitiveness when applying for independent external research funding.

the Fellowship, named in honour of emerita Professor Judith Whitworth, past director of the JcsMR, and supported by JcsMR and the John curtin Medical Research Foundation is believed to be the of its kind to be established at an Australian University.

1. ANU Vice-Chancellor Professor ian young with ACT Chief Minister Ms Katy Gallagher, Emerita Professor judith Whitworth and jCsMr director Professor Chris Parish at the ceremony to launch the inaugural judith Whitworth fellowship 2. Professor judith Whitworth3. inaugural judith Whitworth fellowship recipient dr julia Ellyard and ACT Chief Minister Ms Katy Gallagher with Professor judith Whitworth4. Ms Katy Gallagher, Chair of The john Curtin Medical research foundation Board dr Cameron Webber, and dr julia Ellyard

tHe InAUGURAL JUDItH WHItWoRtH FeLLoWsHIP At JcsMR

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tHe JoHn cURtIn MeDIcAL ReseARcH FoUnDAtIon 2nD AnnUAL DInneR

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nobel Laureate Professor J Robin Warren provided fascinating insights into his work when interviewed by Mr Ken Begg at the 2nd Annual Dinner of the the John curtin Medical Research Foundation in August.

Held at University House, the Dinner was a huge success, and included raffles, silent auctions and entertainment. thanks to generous supporters the John James Foundation and Mr Ron and Mrs Janice Parker, funds were donated at the dinner to finalise the purchase of an intravital microscope to be used in research projects on cancer, malaria prevention and the study of autoimmune diseases at AnU.

For more information about the John curtin Medical Research Foundation please visit: jcmrf.anu.edu.au

1. Chair of the jCMrf Board dr Cameron Webber, Nobel laureate Professor j robin Warren and ANU Vice-Chancellor Professor ian Young2. (l-r) Mr Phil Greenwood, dr Cameron Webber, Mr Brian Acland, Mr Mark sullivan, Professor j robin Warren, Professor Paul smith and dr jeff harmer 3. Ms janet henry, Ms Marilyn fenner and Ms diana lipscombe4. Nobel laureate Professor j robin Warren was interviewed by jCMrf Board Member Mr Ken Begg

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Annual Review 2014 11

LAUncH oF tHe centRe FoR PeRsonALIseD IMMUnoLoGY

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Assistant Minister for Health, senator Fiona nash, launched the centre for Personalised Immunology at JcsMR by on Monday 28 April, 2014. 

the principal objective of the centre for Personalised Immunology is to understand pathophysiological pathways in patients presenting with immunological disease, in order to make diagnoses more accurate, and treatment more effective.

the centre aims to help people with immune diseases by discovering causative genetic variation, with the goal of delivering treatment strategies targeted to the individual.

1. directors of the Centre for Personalised immunology, Professor Carola Vinuesa and Professor Matthew Cook2. At the launch of the Centre for Personalised immunology: (front row) ANU Vice-Chancellor Professor ian Young, CPi director Professor Carola Vinuesa, senator fiona Nash, CPi director Professor Matthew Cook, jCsMr director Professor Chris Parish, ANU deputy Vice Chancellor (research) Professor Margaret harding. (Back row) dr dan Andrews, Mr Matthew field and Professor stephen Alexander 3. senator fiona Nash, Professor Chris Parish, Professor Carola Vinuesa, Professor Matthew Cook and Professor ian Young 4. senator fiona Nash officially launches the Centre for Personalised immunology at jCsMr in April 2014

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the Australian national University and the Act Government announced the appointment of distinguished medical researcher Professor Ross Hannan as the inaugural centenary chair in cancer Research in november 2014.

the centenary chair is a new position, focused on researching new treatments for cancer patients and fostering collaboration between canberra medical specialists and scientists at the John curtin school of Medical Research and across AnU.

the centenary chair is a joint project of AnU and the Act Government, established to celebrate the centenary of canberra, which took place in 2013. the Act Government provided $1.5 million to help fund the position.

1. ACT Chief Minister Ms Katy Gallagher with newly appointed Centenary Chair in Cancer research, Professor ross hannan 2. john Curtin Medical research foundation (jCMrf) Board Member dr Peter jeffery with Mrs joanna Webber and jCMrf Chair dr Cameron Webber oAM at the Welcome for the Centenary Chair in Cancer research at jCsMr 3. jCsMr director Professor simon foote with ACT Chief Minister Ms Katy Gallagher4. Newly appointed Centenary Chair in Cancer research, Professor ross hannan addresses guests at the welcome reception

WeLcoMe to tHe centenARY cHAIR In cAnceR ReseARcH PRoFessoR Ross HAnnAn

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Annual Review 2014 13

tHe sARAH GRAce sARcoMA FoUnDAtIon scHoLARsHIP At JcsMR

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In the fight to ‘Kick sarcoma’, the sarah Grace sarcoma Foundation has been tirelessly fundraising in Australia and singapore to support sarcoma research at JcsMR, and currently funds a named PhD scholarship at the school.

Mr Jinsoo Yoon is the first recipient of that scholarship, studying in the Department of Immunology under the supervision of Professor chris Parish and Dr Lucy coupland.

1. Board members of the sarah Grace sarcoma foundation, Australian Paralympian Ms Ellie Cole and Mr hugh Archer, present a cheque to ANU dVC (research) Professor Margaret harding in february2. dr Grace Moshi and scholarship recipient Mr jinsoo Yoon 3. jazzy (left) and Nadia (right) travelled to jCsMr from singapore to present a further cheque for $53,000 to Professor Chris Parish, jCsMr director Professor simon foote, Mr jinsoo Yoon and dr lucy Coupland from sarah Grace sarcoma foundation in November4. Mr jinsoo Yoon expressed his thanks for the efforts of the sarah Grace sarcoma foundation, and said it made him even more determined to work towards an understanding of sarcoma metastasis

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AWARD oF tHe InAUGURAL JoHn JAMes FoUnDAtIon tonY AYeRs PRIZe FoR eXceLLence In tRAnsLAtIonAL MeDIcIne

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the John James Foundation has established a Prize for excellence in Research in translational Medicine at the AnU college of Medicine, Biology and environment in honour of long term Board member Mr tony Ayers Ac. the Prize is awarded to an early – Mid career Research scientist within cMBe who has made a most significant contribution to translational Research, over the course of their research career.

the inaugural tony Ayers Prize was awarded in october 2014 to Dr Anneke Blackburn, Department of Molecular Bioscience, JcsMR, who presented the tony Ayers Lecture: Targeting cancer cell metabolism with dichloroacetate.

1. dr Anneke Blackburn with her family after the ceremony 2. dr Anneke Blackburn, dr james d’rozario, dr lucy Coupland and Chair of the john james foundation Professor Paul smith3. Ms Eleanor hing fay, ANU Vice Chancellor Professor ian Young, CEo of the john james foundation Mr Phil Greenwood, and dean of the ANU College of Medicine Biology and Environment Professor Kiaran Kirk4. dean of the ANU College of Medicine Biology and Environment Professor Kiaran Kirk and Chair of the john james foundation Professor Paul smith present the inaugural Tony Ayers Prize to dr Anneke Blackburn

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Annual Review 2014 15

oPen DAY At JcsMR 2014

open Day at JcsMR takes place in August every year.

everyone in our local community is warmly invited to visit us on open Day to see inside our laboratories, take a Discovery tour of our building, talk with a scientist about their work, and hear about our important research in areas including cancer, diabetes, vision, autoimmune disease, malaria prevention and more.

For information about our next open Day, please visit

jcsmr.anu.edu.au

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DIRectoR’s cHRIstMAs MoRnInG teA FoR FRIenDs AnD sUPPoRteRs oF JcsMR

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every year the Director hosts a christmas morning tea to celebrate the successes of the past year, and to thank friends of JcsMR for their continued interest in our work, and support for our research.

In December 2014, committee members of the canberra Medical society attended the morning tea to present a cheque in support of the newly established national centre for Indigenous Genomics at JcsMR.

1. Professor Carola Vinuesa with john Curtin Medial research foundation Board members Ms Marilyn fenner2. Mr Michael dobbie, Ms janet henry, jCsMr director Professor simon foote, Ms Marilyn fenner and Mrs joanna Webber3. dr Peter Gibson, Treasurer of the Canberra Medical society presents a cheque to Professor simon Easteal, director of the National Centre for indigenous Genomics4. jCsMr director Professor simon foote, Mr Garry humphries, Professor Carola Vinuesa and Chair of the john Curtin Medical research foundation dr Cameron Webber at the director’s Christmas Morning Tea

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Annual Review 2014 17

oUR JcsMR coMMUnItY

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1. The 2014 ACT final of the Australasian Brain Bee Challenge was won by shruthisri sridharan, of Burgmann Anglican school, picture here with Professor Greg stuart, head of the jCsMr Eccles institute of Neuroscience 2. dr jason Potas, Mr Michael Bootes and dr Charani ranasinghe at a morning tea to meet the Board of the Gordon and Gretel Bootes foundation 3. Ms Emilie rohan, Ms dianne Garner, and dr Corinne Carle at the Bootes foundation morning tea at jCsMr 4. Members of The Canberra ionians Group, who visited the Cancer Metabolism and Genetics laboratory headed by dr Anneke Blackburn (far right) in August5. To celebrate international Women’s day in March, Ms joy Burch, ACT Minister for Women and ACT Minister for Youth hosted a ‘Girls in science’ morning tea at jCsMr6. Ms joy Burch addresses young women from Canberra high schools and Colleges as part of the Girls in science event held in conjunction with international Women’s day in March

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1. National Youth science forum students visited jCsMr laboratories in january2. in october, jCsMr hosted a special scientific symposium to pay tribute to Philip Board’s remarkable contribution to Australian and international science: The 15th frank and Bobbie fenner Conference: Professor Philip Board symposium. (l-r) Professor Bengt Mannervik, Associate Professor Aaron oakley, Associate Professor Marco Casarotto, Professor Phil Board, dr lars jermiin, Professor Angela dulhunty, dr jack flanagan, Professor Michael Parker, dr rohan Baker and Professor jane dahlstrom3. Executive members of the Tokyo Medical and dental University, led by Professor Yoshi Eishi, visited jCsMr 4. Mr ray and Mrs Alice Pelham-Thorman with ANU Alumnus Professor Yoshinobu Eishi, now dean of Medicine at Tokyo Medical and dental University, renewing a friendship which began while Professor Eishi was a student at jCsMr 5. Australian federal Minister for health The hon. Mr Peter dutton’s visit to the jCsMr department of immunology6. in december, staff and students gathered to celebrate the retirement of four of our longstanding colleagues – Professor Klaus Matthaei, Professor Caryl hill, Professor Philip Board and Professor Bruce Walmsley. 119 years, 99 students and over 700 publications. What an achievement!

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oUR JcsMR coMMUnItY

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Annual Review 2014 21

Staff and Student AchievementsGraduates

Prizes, Honours and Awards

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GRADUAtes

PhD

Rizalyn Sarda Albarracinthe therapeutic Potential of 670nm Light in Retinal Degeneration

Hans Christoph Tobias Bockthe Impact of calcium-Activated Potassium channels on Dendritic excitability in cortical Layer 5 Pyramidal neurons

Soek-Yeng ChanRole of DocK8 and hnRnPLL in cD8 t cell survival

Daniel John Chaston

the Role of endothelial connexin40 in the Regulation of Arterial Function and Blood Pressure

Fui Jiun ChoongRoles for Islet Heparan sulfate and Heparanase in Islet transplantation

Bevan Gangtargeting cancer Metabolism

Mary Ann Go

Precise optical Manipulation techniques for exploring neuronal Function

ShuYi (Sophie) Han

Histone Variant H2A.Z: A Master Regulator of epithelial-to-Mesenchymal transition

Amy Dianne HannaMechanisms of Anthracycline-induced Dysfunction of ca2+ Handling Proteins in the Heart

Carly Jane HynesInvestigating the complexities of MicroRnA-target Interactions in cardiac Biology

Jing Jieffects of Heat Labile enterotoxin B subunit on Murine Dendritic cells

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Annual Review 2014 23

Scott Lewis Jones

on the Function of somatic and Dendritic sK channels in cortical Pyramidal neurons

HieRin Leethe Development of seahorse Vision: Morphological and Behavioural Aspects

Suhyun Lee

Long-term Metabolic effects of stress and Antidepressants: A novel Paradigm of Antidepressant-Induced Weight Gain in the Post-stress Acclimation Period

Jasmine Li

nuclear Protein Kinase c-theta and Permissive chromatin states co-ordinate transcriptional Memory Responses in Human t cells

Linwei Li

In Vitro exploration of Interactions Between Junctin and the Ryanodine Receptor from skeletal and cardiac Muscle

Sally Jane Mapp

Genetic Mutations Promoting Autonomous B cell Proliferation

Ameet Kumar Mishra

Leptin: Linking obesity to Breast cancer Progression

Susan Kaye Morton

the Role of endothelial connexin40 in the Regulation of Activity-Dependent Blood Pressure elevation

Robyn Tricia Rebbeck

Interactions between the Dihydropyridine Receptor Beta1A subunit and the Ryanodine Receptor from skeletal Muscle

Zahra Sabouri-Thompson

Positive and negative selection of Antibodies in Germinal centres

Monika Srivastava

Regulation of miRnA Homeostasis by Roquin

Andrea Stojakovic

Long-term effects of LPs and High-Fat Diet on Dopaminergic neurodegeneration

Dijana Townsend

Role of eosinophils in Respiratory syncytial Virus Infection

Danushka Kumara Wijesundara

HIV-1 Vaccine Development: evaluating Mechanisms of cD8+ t cell Avidity

Hermia Willemse

towards Understanding ec coupling Protein expression with Age

Elize Wium

Identifying the in vitro Interactions between the skeletal Muscle Ryanodine Receptor, triadin and calsequestrin

Mehmet Yabas

B cell Deficiency and Anaemia caused by Mutations in the Murine Atp11c Gene

MPhil

Jayashree Ravichandran

Role of IL-17 in HIV specific cD8+t cell Immunity

MNeuroscience (Research)

Farhia Haque

Indumathi Ravi

Conor Owens Walton

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24 the John curtin school of Medical Research

1 2

3 4

PRIZes AnD AWARDs

Dr Rizalyn Sarda Albaraccin AnU Alumni Award – 2014 Postgraduate student of the Year

Mr Hannes BergannAustralasian society of Immunology travel Award

Dr Anneke Blackburnthe 2014 John James Foundation tony Ayers Prize for excellence in translational Medicine, AnU college of Medicine, Biology and environment

Ms Fui Jiun Choongcanberra Hospital Private Practice Fund Award for Best student oral presentation: Molecular insights into the loss of heparan sulfate (HS) during islet isolation and HS recovery after islet transplantation, the canberra Health Annual Research Meeting, canberra, Act

Dr Stephen Daleythe Gordon Ada early career Researcher Award. Presented to an early career Researcher at JcsMR who has made major contributions to biomedical research

Ms Sarita DhounchakAnU cMBe Prize for Best Poster Presentation: Beta cell heparan sulfate and heparan sulfate proteoglycan loss in Type 2 Diabetes, the Australian society for Medical Research (AsMR) Act Branch new Investigator Forum, canberra, Act

Dr Julia Ellyardthe inaugural Judith Whitworth Fellowship for Gender equity in science

Ms Nilisha FernandoeMBL Australia travel Grant to attend the 16th eMBL International PhD symposium, Heidelberg, Germany

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Annual Review 2014 25

5 6

7 8

Professor Simon Footeelected as Fellow, the Australian Academy of Health and Medical sciences

Appointed Director, the John curtin school of Medical Research, AnU

Dr Simon JiangAustralian Government Postgraduate scholarship to investigate the development of systemic lupus erythematosus

Dr Yalin Liaotravel award to attend the Global Young scientist summit, one north, singapore

AnU early career Researcher’s (ecR) travel Award: to attend the eMBL conference: Complex life of RNA, eMBL Heidelberg, Germany

sIeF John stocker Postdoctoral Fellowship

Ms Susan MortonInternational society of cardiovascular Pharmacotherapy student travel Grant to attend experimental Biology 2014, san Diego, cA, UsA

Dr Jason PotasAnU excellence in teaching Awards, Best Faculty teacher Phase 1, AnU Medical school

Finalist: Your Science in 60 Seconds. science Meets Parliament

1. Professor Carola Vinuesa was awardee the inaugural Csl Young florey Medal2. Nobel laureate Emeritus Professor rolf Zinkernagel was awarded the Curtin Medal for 20143. dr stephen daley received The Gordon Ada Early Career researcher Award for 20144. Professor Greg stuart was invited to present the 4th Annual john Curtin lecture by jCsMr director Professor Chris Parish5. Chair of the john james Memorial foundation presents the inaugural Tony Ayers Prize for Excellence in Translational Medicine to dr Anneke Blackburn6. ANU Alumni Awards – Postgraduate student of the year – rizsa Albarracin 7. Professor Thomas Preiss8. dr julia Ellyard, jCsMr director Professor simon foote and Emerita Professor judith Whitworth following the award of the inaugural judith Whitworth fellowship for Gender Equity in science

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26 the John curtin school of Medical Research

Professor Chris Parishthe chancellor’s Award for Distinguished contribution to the University for 2014

Act citizen of the Year 2014

Mr Alvin PratamaAsI travel bursary to attend the 44th Annual scientific Meeting of the Australasian society for Immunology, Wollongong, nsW

scholarship to attend the croucher summer course 2014: Advances in Immunology in Health and Disease, Department of Medicine, the University of Hong Kong, Hong Kong

AnU Vice-chancellor’s Postgraduate travel Grant

AsI Postgraduate International travel Award

Professor Thomas Preissthe Julian Wells Medal and Lecture, the Lorne Genome conference, Lorne, VIc

Dr Jennifer RobertsonPoster Prize, Runner up – the Australian society for Medical Research (AsMR) Act Branch new Investigator Forum, canberra, Act

Mr Manu SinghViewer’s choice Prize for Best Poster, the Australian society for Medical Research (AsMR) Act Branch new Investigator Forum, canberra, Act

Ms Rina SoetantoViewer’s choice prize for Best oral Presentation, and Prize for Best Poster – the Australian society for Medical Research (AsMR) Act Branch new Investigator Forum, canberra, Act

Prize for Best oral Presentation: The dynamics of miRNA-mRNA targeting during cardiac health and disease. eMBL Australia PhD symposium, sydney, nsW

Runner-up, AnU 3-Minute thesis competition: Mending a broken heart- a big role for small RNAs. AnU colleges of science, AnU, canberra, Act

Dr Zan-Min SongAnU excellence in teaching Awards, Best Faculty teacher Phase 1, AnU Medical school

Professor Greg Stuartthe 4th Annual John curtin Lecture in Medical Research ‘Brain Mechanics: The nuts and bolts of how your brain works’

Mr Malinda Tantirigamaearly career Researcher Award for excellence: UWs sensory neuroscience symposium, University of Western sydney, sydney, nsW

Dr Krisztina Valter- Kocsi Promoted to Associate Professor

elected as a senior Fellow of Higher education Academy UK

Inaugural member of the education Fellowship scheme committee, AnU

Professor Carola Vinuesathe inaugural csL Young Florey Medal for her research into how the immune system produces antibodies to fight disease

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Annual Review 2014 27

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28 the John curtin school of Medical Research

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Annual Review 2014 29

Visitors and CollaborationsResearch Collaborations and Visitors to the School

Visitors to JcsMR present their research findings through Group, Department or school seminars and workshops, and collaborate with our staff and students in our world-class research facilities.

staff and students at JcsMR continue to enjoy close collaborative ties with other researchers at the Australian national University. In addition, they enjoy scientific associations with colleagues locally, regionally, national and internationally.

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30 the John curtin school of Medical Research

VIsItoRs

Professor David J AdamsHealth Innovations Research Institute, RMIt University, Melbourne, VIc

Professor Juan-Manuel Anayacenter for Autoimmune Diseases Research (cReA), Rosario University, Bogotá, colombia

Dr Anthony AshtonUniversity of sydney, sydney, nsW

Dr Ulus AtasoyMolecular Microbiology and Immunology, University of Missouri school of Medicine and Harry s truman Veterans Hospital, columbia, Mo, UsA

Associate Professor Tony BadrickFaculty of Health sciences and Medicine, Bond University, Gold coast, QLD

Dr Rohan Bakerclinical Genomics, sydney, nsW

Professor Jacques Banchereau the Jackson Laboratory for Genomic Medicine, Farmington, ct, UsA

Dr Vladimir BenesGenomics core Facility, european Molecular Biology Laboratory, Heidelberg, Germany

Professor John CarverResearch school of chemistry, AnU college of Physical & Mathematical sciences, the Australian national University, canberra, Act

Professor Archie Clementsthe national centre for epidemiology and Population Health, AnU college of Medicine, Biology and environment, the Australian national University, canberra, Act

Professor Colin Cliffordschool of Psychology, the University of new south Wales, sydney, nsW

Professor Stephen DaltonDepartment of Biochemistry and Molecular Biology, the University of Georgia, Athens, GA, UsA

Professor Mathew DiamondInternational school for Advanced studies (sIssA), trieste, Italy

Dr Christian EngwerdaImmunology and Infection Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, QLD

Associate Professor Lindy Fitzgeraldschool of Animal Biology, the University of Western Australia, crawley, WA

Professor Simon Footethe Australian school of Advanced Medicine, Macquarie University, sydney, nsW

Professor Paul Fosterschool of Biomedical sciences and Pharmacy, the University of newcastle, newcastle, nsW

Professor Simon Gandevianeuroscience Research Australia, sydney, nsW

Professor Ross D Hannanthe Peter Maccallum cancer centre, Melbourne, VIc

Professor Edna Hardemanneuromuscular and Regenerative Medicine Unit, school of Medical sciences, University of new south Wales, sydney, nsW

Assistant Professor Christian HennebergerInstitute of cellular neurosciences, University of Bonn Medical school, Bonn, Germany

Professor Ian HickieBrain and Mind Research Institute, University of sydney, sydney, nsW

Professor Philip HugenholtzAustralian centre for ecogenomics, school of chemistry and Molecular Biosciences, University of Queensland, Brisbane, QLD

Associate Professor Katherine KedzierskaDepartment of Microbiology and Immunology, school of Biomedical sciences, the University of Melbourne, Melbourne, VIc

Professor Trevor KilpatrickDivision of Multiple sclerosis, the Florey Institute for neuroscience and the Melbourne neuroscience Institute, the University of Melbourne, Melbourne, VIc

Professor Bostjan Kobeschool of chemistry & Molecular Biosciences, University of Queensland, Brisbane, QLD

Professor Eddy FY LiewDivision of Immunology, Infection and Inflammation, University of Glasgow, Glasgow, scotland

Dr Charles H LineweaverAnU Planetary science Institute – Mount stromlo observatory, Research school of Astronomy and Astrophysics, AnU college of Physical and Mathematical sciences, the Australian national University, canberra, Act

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Annual Review 2014 31

Professor Kate LovelandDepartment of Biochemistry & Molecular Biology and Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIc

Dr Yuerui Lu

Research school of engineering, AnU college of engineering and computer science, the Australian national University, canberra, Act

Associate Professor Michele Madiganschool of optometry & Vision science, University of new south Wales, sydney, nsW and save sight Institute and Discipline of ophthalmology, University of sydney, sydney, nsW

Dr Germán Manríquez Faculty of Medicine and Faculty of social sciences, University of chile, santiago, chile

Professor Justin Marshallsensory neurobiology, Queensland Brain Institute, the University of Queensland, Brisbane, QLD

Dr Jose DeLeonDepartment of Psychiatry, University of Kentucky, Lexington, KY, UsA

Professor Sonya Marshall-Gradisnikschool of Medical science, Griffith University, Gold coast, QLD

Professor John MattickGarvan Institute of Medical Research, sydney, nsW

Professor Jason B Mattingleycognitive neuroscience, Queensland Brain Institute and the school of Psychology, the University of Queensland, Brisbane, QLD

Professor Michael S MooreProgram in Law and Philosophy, college of Law, the University of Illinois, champaign, IL, UsA

Professor Eric Morandschool of clinical sciences, Monash Health and Faculty of Medicine, nursing & Health sciences, Monash University, Melbourne, VIc

Dr Maximilian MuenkeMedical Genetics Branch, national Human Genome Research Institute, national Institutes of Health, Bethesda, MD, UsA

Dr Gabe Murphy Janelia Research campus, Howard Hughes Medical Research Institute, Ashburn, VA, UsA

Assistant Professor Ki Taek NamDepartment of Materials science and engineering, seoul national University, seoul, Korea

Professor Christopher NolanDiabetes Research Laboratory, endocrinology Unit, canberra Hospital, canberra, Act

Professor Virginia Pascualcenter for Inflammation and Autoimmune Diseases and center for Personalized Medicine, Baylor Research Institute, Dallas, tX, UsA

Dr Nicholas PriceDepartment of Physiology, Monash University, Melbourne, VIc

Professor Markus SchlaichHypertension and Kidney Disease, Baker IDI Heart and Diabetes Institute, Melbourne, VIc

Professor Gordon SmythDivision of Bioinformatics, the Walter and eliza Hall Institute of Medical Research, Melbourne, VIc

Professor Mandyam SrinivasanVisual and sensory neuroscience, Queensland Brain Institute, the University of Queensland, Brisbane, QLD

Professor Seong-Seng TanBrain Development, the Florey Institute of neuroscience and Mental Health, Melbourne, VIc

Dr Illa Tea University of nantes, nantes, France

Professor Joseph Trapanicancer cell Death Laboratory, the Peter Maccallum cancer centre, Melbourne, VIc

Dr Richard UlevitchDepartment of Immunology and Microbial science, the scripps Research Institute, La Jolla, cA, UsA

Professor Mark von ItzsteinInstitute for Glycomics, Griffith University, southport, QLD

Dr Linda WakimDepartment of Microbiology and Immunology, the University of Melbourne, Melbourne, VIc

Professor Wolfgang Weningercentenary Institute of cancer Medicine and cell Biology, the University of sydney, sydney, nsW

Laureate Professor Rolf Zinkernagelthe University of Zurich, Zurich, switzerland

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32 the John curtin school of Medical Research

Ms Nur Diana Anuar, Dr Tatiana A Soboleva and Professor David Tremethick An investigation on the role of histone variant H2A.Lap1

Professor P Koopman, J Bowles and T-L Davidson Institute for Molecular Bioscience, the University of Queensland, Brisbane, QLD Dr PD Gregory and Dr L Zhang sangamo Biosciences Inc., Richmond, cA, UsA Dr R Arkell Research school of Biology, the Australian national University, canberra, Act Professor JE Dahlstrom Department of Pathology, canberra Hospital, canberra, Act Dr D Andrews and Mr M Field Department of Immunology, the John curtin school of Medical Research, AnU, canberra, Act

Associate Professor Ehsan ArabzadehWhisker sensory system, from receptor to behaviour

Professor M Diamond International school for Advanced studies, trieste, Italy

Contribution of layers 2/3 on sensory processing in mouse barrel cortex

Professor L Richards Queensland Brain Institute, Brisbane, QLD

Neuronal and behavioural correlates of choice

Professor F Westbrook Department of Psychology, University of new south Wales, sydney, nsW

The role of context in sensory processing

Dr N Price Department of Physiology, Monash University, clayton, VIc

Associate Professor Mauricio Arcos-BurgosGenetics of ADHD and disruptive behaviours

Dr M Muenke national Human Genome Research Institute, national Institutes of Health, Bethesda, MD, UsA

Dr M Casas, Dr J-A Ramos-Quiroga and Dr M Ribases Vall d’Hebron Institut de Recerca (VHIR) through the International Multicentre Persistent ADHD collaboration consortium (IMPAct), Barcelona, spain

Dr MT Acosta children’s’ national Hospital, children’s Research Institute (cRI), Washington, Dc, UsA

Genetics of autoimmune disorders

Dr J-M Anaya centre for Autoimmune Diseases Research, University of Rosario, Bogota, colombia

Genetics of ADHD

Dr M Bellgrove school of Psychological sciences, Monash University, Melbourne, VIc

Genetics of Major Depressive Disorder and genetics of Morbid Obesity

Professor J Licinio and Professor M-L Wong translational Medicine, Flinders University, Adelaide, sA and south Australian Health and Medical Research Institute, Adelaide, sA

Genetics of substance use disorders

Dr J DeLeon Department of Psychiatry, University of Kentucky, Lexington, KY, UsA

Genetics of ADHD

Dr F Levy school of Psychiatry, University of new south Wales, Randwick, nsW,

Genetics of Alzheimer’s Disease and mild cognitive impartment, and genetics of disphemia

Dr F Lopera neurosciences Group, University of Antioquia, Medellín, Antioquia, colombia

Dr Vicki AthanasopoulosIdentifying protein-protein interactions with an unnatural photocrosslinking amino acid.

Professor G Otting Research school of chemistry, the Australian national University, canberra, Act

Professor John M BekkersExcitability and hyperexcitability of neural circuits in the rodent piriform cortex

Professor S Nelson Brandeis University, Waltham, MA, UsA Professor G Augustine national University of singapore, singapore; Korea Institute of science and technology, seoul, south Korea; Lee Kong chian school of Medicine, singapore

Neural circuits for odour-processing in the rodent piriform cortex ‘in vivo’

Professor M Larkum charité-Humboldt University, neuroscience Research center, Berlin, Germany

Persistent firing in cortical interneurons: Mechanisms and potential anticonvulsant role

Dr M McDonnell Institute of telecommunications Research, University of south Australia, Adelaide, sA

Epilepsy in the piriform cortex

Dr C Reid Florey Institute, Melbourne, VIc

Dr Andrew BellStudies of otoacoustic emissions from the human cochlea

Dr W Jedrzejczak Institute of Physiology and Pathology of Hearing, Warsaw, Poland

Computer modelling of cochlear mechanics

Professor HP Wit University of Groningen, the netherlands

Dr Edward M Bertram and Professor Chris C GoodnowChina-Australia Centre for Phenomics Research

Professor H Tang centre for Infection and Immunity, chinese Academy of sciences, Institute of Biophysics, china

Dr Anneke C BlackburnMouse mammary tumour susceptibility loci

Professor DJ Jerry Veterinary and Animal sciences, University of Massachusetts, Amherst, MA, Us

Targeting breast cancer with dichloroacetate and the mitochondrial toxin PENAO

Professor PJ Hogg and Dr PJ Dilda Lowy cancer Research centre, University of new south Wales, sydney, nsW

Targeting of Two Aspects of Metabolism (TOTAM) for Cancer Therapy

Professor JE Dahlstrom Anatomical Pathology, Act Pathology, canberra Hospital and AnU Medical school, the Australian national University, canberra, Act Associate Professor D Yip Medical oncology, canberra Hospital, canberra, Act and AnU Medical school,

coLLABoRAtIons

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Annual Review 2014 33

the Australian national University, canberra, Act

Isotopic signature of 13C and 15N natural abundance in breast cancer

Dr I Tea University of nantes, nantes, France

A Centre for Oncology Education and Research Translation (CONCERT)

Professor P deSouza Liverpool Hospital, sydney, nsW

Dr Anneke C Blackburn and Dr Lucy Coupland Phase 2 Clinical Trial of Dichloroacetate in Plateau Phase Myeloma

Dr S Bennett, Dr J D’Rozario and Dr P Crispin Haematology, canberra Hospital, canberra, Act

Professor Philip G BoardDetermination of glutathione transferase structures

Professor M Parker st Vincent’s Medical Research Institute, Melbourne, VIc

Function of Zeta and Omega class GSTs

Professor MW Anders Department of Pharmacology and Physiology, University of Rochester Medical centre, Rochester, nY, Us

Structure of γ-glutamyl cyclotransferase

Associate Professor A Oakley school of chemistry, University of Wollongong, Wollongong, nsW

The expression of γ-glutamyl cyclotransferase in human cancer

Professor Y Eishi and Dr K Takemura Department of Human Pathology, tokyo Medical and Dental University, tokyo, Japan

The role of Omega class GSTs in TLR4 signalling

Professor L O’Neill and Dr R Coll school of Biochemistry and Immunology, trinity Biomedical sciences Institute, trinity college, Dublin, Ireland

Dr Anne BreustleAntigen receptor mediated depletion of FOXP3 in induced regulatory T lymphocytes via PTPN2 and FOXO1

Dr E Bothur and Professor M Lohoff Institute for Medicine, Microbiology and Hygiene, Philipps-University, Marburg, Germany

The role of MALT1 in autoimmunity and tolerance

Dr D Brenner Department of Infection and Immunity, Luxembourg Institute of Health, Luxembourg Professor TW Mak campbell Family Institute for Breast cancer Research, ontario cancer Institute, Princess Margaret Hospital, toronto, on, canada Dr T Calzascia novartis Institutes for BioMedical Research, novartis Basel, switzerland

Antioxidant glutathione in autoimmunity and cancer

Dr I Harris and Professor TW Mak campbell Family Institute for Breast cancer Research, ontario cancer Institute, Princess Margaret Hospital, toronto, on, canada Dr D Brenner Department of Infection and Immunity, Luxembourg Institute of Health, Luxembourg

UVRAG in Autoimmunity

Dr S Afzal and Professor TW Mak campbell Family Institute for Breast cancer Research, ontario cancer Institute, Princess Margaret Hospital, toronto, on, canada

Dr Marco G CasarottoMolecular recognition of the ryanodine receptor

Dr M Samso Department of Physiology and Biophysics, VcU school of Medicine, Richmond, VA, Us

Design and development of M2 influenza A inhibitors

Professor Wenhui Hu Guangzhou Institute of Biomedicine and Health, chinese Academy of sciences, science Park, Guangzhou, china

Interactions between the alpha and beta subunits of the dihydropyridine receptor

Assistant Professor C Perez Brigham and Women’s Hospital, Harvard University, Boston, MA, UsA Associate Professor A Oakley Department of chemistry, University of Wollongong, Wollongong, nsW

Dr A Bjorksten Department of Pain and Anesthesia, Royal Melbourne Hospital, Melbourne, VIc

Mr Aaron ChuahAlpine Frog and Bettong Genotyping by Sequencing

Dr S Banks Fenner school of environment and society, the Australian national University, canberra, Act

Brachypodium, Eucalypt & Coconut Genotyping by Sequencing

Professor J Borevitz Research school of Biology, the Australian national University, canberra, Act

Australian Native Plants Genotyping by Sequencing

Dr E James Royal Botanic Gardens, Melbourne, VIc

Australian Alpine Plant Genotyping By Sequencing

Dr A Miller Departments of Zoology and Genetics, Faculty of science, the University of Melbourne, Melbourne, VIc

Pelargonium Genotyping by Sequencing

Associate Professor A Nicotra, Research school of Biology, the Australian national University, canberra, Act

Oil Palm Genotyping by Sequencing

Dr M Ithnin Malaysian Palm oil Board, Kuala Lumpur, Malaysia

Kelp and Seaweed Genotyping by Sequencing

Dr C Fraser Fenner school of environment and society, the Australian national University, canberra, Act

Professor JM Waters, Department of Zoology, University of otago, new Zealand

Stonefly Genotyping by Sequencing

Dr N Dussex, Department of Zoology, University of otago, new Zealand

Choerodon Genotyping by Sequencing

Ms K Cure school of Plant Biology, University of Western Australia, Perth, WA

Craspedia and Ozothamnus Genotyping by Sequencing

Dr A Schmidt-Lebuhn csIRo Plant Industry canberra, Act

Cotton RNAseq differential expression analysis

Dr C MacMillan csIRo Plant Industry, canberra, Act

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34 the John curtin school of Medical Research

Arabidopsis Variant Calling in Amplicons

Dr J Barrero, csIRo Plant Industry, canberra, Act

Myrtle rust RNAseq transcriptome assembly and differential expression analysis

Dr C Kulheim, Research school of Biology, the Australian national University, canberra, Act

Murine RNAseq differential expression analysis

Dr H Tay school of Biomedical sciences and Pharmacy, newcastle University, newcastle, nsW

Mr Aaron Chuah, Emeritus Professor Trevor Lamb and Dr Hardip PatelRNAseq retinal gene comparative transcriptomics and TriPyGDU browser

Emeritus Professor D Hunt Lions eye Institute & University of Western Australia oceans Institute, the University of Western Australia, Perth, WA

Associate Professor Ian CockburnImaging the CD8+ T cell response to malaria parasites in the liver

Dr R Amino and Dr R Menard Institut Pasteur, Paris, France Assistant Professor V Ganusov theoretical Immunology Laboratory, University of tennessee, Knoxville, tn, UsA

Understanding B cell responses to malaria vaccine antigens at the single cell level

Dr R Seder Vaccine Research centre, national Institute of Allergy and Infectious Diseases, national Institutes of Health, Bethesda, MD, UsA Dr F Ndungu Kenya Medical Research Institute, KeMRI-Wellcome trust Research Programme, Kilifi, Kenya Professor K Marsh nuffield Department of Medicine, University of oxford, oxford, UK

Professor Matthew C CookAustralian and New Zealand Antibody Deficiency Allele (ANZADA) study

Dr S Adelstein and Dr R Garsia Department of Immunology, Royal Prince Alfred Hospital, camperdown, nsW Dr T DeMalmanche HAPs Immunology, newcastle, nsW Dr P Hissaria Royal

Adelaide Hospital, Adelaide, sA Dr M French school of Pathology and Laboratory Medicine, the University of Western Australia, Perth, WA Dr S Choo Royal Melbourne children’s Hospital, Melbourne, VIc Professor D Campbell and Dr S Mehr the children’s Hospital at Westmead, Westmead, nsW Dr s Riminton Department of Immunology, concord Repatriation General Hospital, concord, nsW Dr D Fulcher Department of Immunopathology, the children’s Hospital at Westmead, Westmead, nsW

Genomic medicine for human immune deficiency

Dr D Tscharke Research school of Biology, the Australian national University, canberra, Act Dr D Fulcher Department of Immunopathology, the children’s Hospital at Westmead, Westmead, nsW

A randomised trial to assess antibody and cellular responses to hepatitis B vaccine in patients with chronic kidney disease (VaccineCKD)

Dr K Karp canberra Hospital, canberra, Act

CCR5 expression on B cells in immune deficiency

Professor H Korner University of tasmania, Hobart, tAs

STAT3 and hyper IgE syndrome

Dr S Tangye Garvan Institute of Medical Research, sydney, nsW

Professor Matthew C Cook and Dr Stephen DaleyImmune response after adult thymectomy

Professor G Chong canberra Hospital, canberra, Act

Professor Matthew C Cook and Professor Chris C GoodnowCell of origin of B cell Non-Hodgkin’s lymphoma

Dr D Talaulikar canberra Hospital, canberra, Act

Professor Matthew C Cook, Professor Chris C Goodnow and Professor Carola G VinuesaAustralian point mutation in systemic lupus erythematosus (APOSLE) study

Professor P Gatenby canberra Hospital, canberra, Act Dr S Adelstein and Dr R Garsia Department of Immunology, Royal Prince Alfred Hospital, camperdown, nsW Dr D Mallon Fremantle Hospital, Fremantle, WA Dr S Alexander the children’s Hospital at Westmead, Westmead, nsW Dr S Riminton Department of Immunology, concord Repatriation General Hospital, concord, nsW Dr D Fulcher Department of Immunopathology, the children’s Hospital at Westmead, Westmead, nsW

Dr Lucy CouplandMechanisms and novel treatment avenues for auto-immune cytopenias

Dr J D’Rozario and Dr P Crispin Haematology Department, canberra Hospital, canberra, Act

Characterisation of erythrocyte abnormalities in hemoxygenase-1 deficient mice

Professor R Stocker, Dr R Winter and Dr S Fraser sydney Medical school, the University of sydney, sydney, nsW

Dr Lucy Coupland and Dr Anneke BlackburnDichloroacetate in Multiple Myeloma

Dr J D’Rozario, Dr S Bennett and Dr P Crispin Haematology Department, canberra Hospital, canberra, Act

Dr Stephen Daley Pulmonary hypertension caused by a novel ENU-induced variant of Tomm40

Professor L Arnolda the canberra Hospital, canberra, Act and AnU Medical school, the Australian national University, canberra, Act

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Annual Review 2014 35

Dr Vincent DariaBrain-on-a-chip

Professor HA Bachor and Professor C Jagadish Research school of Physics and engineering, the Australian national University, canberra, Act

Adaptive wavefront correction of efficient delivery of light through brain tissues

Dr S Lee Research school of engineering, the Australian national University, canberra, Act

Synthesising photo-switchable nanoparticle agents for cell imaging and analysis

Dr A Tricoli Research school of engineering, the Australian national University, canberra, Act

Analysing Soft-matter interactions using multiple beam optical tweezers

Professor E Sevick Research school of chemistry, the Australian national University, canberra, Act

Professor Angela DulhuntyRyanodine receptor regulation in health and disease

Dr NA Beard centre for Research in therapeutic solutions, University of canberra, Act

Various aspects of ryanodine receptor physiology

Dr D Laver Hunter Medical Research Institute, University of newcastle, newcastle, nsW

Contribution of splicing defects and mutations on ryanodine receptors function

Professor RT Dirksen and Dr L Wei Department of Pharmacology and Physiology, University of Rochester Medical centre, Rochester, nY, UsA

Actions of triadin and calsequestrin on excitation-contraction coupling

Professor RT Dirksen and Dr L Wei Department of Pharmacology and Physiology, University of Rochester Medical centre, Rochester, nY, Us

CPVT mutations in the cardiac RyR and CCD mutations in the skeletal RyR

Professor T Wagenknecht and Dr Z Liu Wadsworth center, new York state Department of Health, Albany, nY, Us

The 3D location of the binding domains in RyR1

Assistant Professor M Samso Department of Physiology and Biophysics, Virginia commonwealth University, Richmond, VA, UsA

Abnormalities in ryanodine receptor activity in human heart failure

Professor C dos Remedios Department of Anatomy, the University of sydney, sydney, nsW

Single channel activity of RyRs from normal human and DM1 muscle

Professor K North and Dr N Clarke Discipline of Paediatrics and child Health, the children’s Hospital at Westmead, the University of sydney, sydney, nsW

New cardiac ryanodine receptor inhibitors for the treatment of heart failure

Professor L Arnolda canberra Hospital, canberra, Act and AnU Medical school, the Australian national University, canberra, Act

Mutations in CLIC-2 proteins leading to ryanodine receptor channelopathy heart failure and intellectual deficit

Professor C Schwartz and Dr E Axelov Jc self Research Institute of Human Genetics, Greenwood Genetic center, Greenwood, sc, UsA and Department of Physics, computational Biophysics and Bioinformatics, clemson University, clemson, sc, UsA

Actions of φ-LITX-Lw1a on ryanodine receptors

Professor C Huang and Dr S Salvage Department of Physiology, Development and neuroscience, University of cambridge, cambridge, UK

Mutations in the ryanodine receptor leading to CPVT and atrial fibrillation

Dr J Smith and Professor P Alewood Institute for Molecular Biosciences, the University of Queensland, st Lucia, QLD

The roles of calsequestrin in fast and slow twitch skeletal muscle

Professor F Protasi cesI, center for Research on Ageing Department of neuroscience and Imaging Università Gabriele d’Annunzio, chieti, Italy

Effects of aging on the distribution of excitation-contraction coupling proteins in human skeletal muscle

Professor P Smith trauma and orthopaedic Research Unit, canberra Hospital, canberra, Act

Effects of the beta subunit of the DHPR on excitation-contraction coupling

Professor M Schneider Biochemistry and Molecular Biology, University of Maryland school of Medicine, Baltimore, MD, UsA

Dr Julia Ellyard and Professor Carola VinuesaLoss-of-fuctional variants in AIRE

Professor P Peterson and Dr M Saare Institute of Molecular and cell Biology, University of tartu, estonia

IFN-alpha secretion in SLE

Professor P Hertzog centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Melbourne, VIc 

Dr Anselm Enders Analysis of the putative phospholipid transporter ATP11C

Professor S Broer Research school of Biology, the Australian national University, canberra, Act

Analysis of liver tumor development in ATP11C deficient mice

Professor N Teoh canberra Hospital, canberra, Act

Analysis of MAIT cell development and function in PLZF mutant mice

Professor D Godfrey Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIc

Analysis of MHC invariant chain processing and development of dendritic cells in SPPL2A deficient mice

Professor J Villadangos Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIc

Genetic analysis of humans with immunodeficiency of unknown aetiology

Professor H Eibel and Professor S Ehl centre for chronic Immunodeficiency, Freiburg, Germany and Professor K Schwarz University of Ulm, Ulm, Germany

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36 the John curtin school of Medical Research

Professor Chris C GoodnowHuman antibody repertoires

Dr D Dunn-Walters King’s college, London, UK Professor D Kipling cardiff University, cardiff, UK

Professor Chris C Goodnow and Dr Edward M BertramMutagenetix – A database of mutations and phenotypes induced by ENU

Professor B Beutler University of texas southwestern Medical center, Dallas, texas, UsA

International Mouse Phenotyping Consortium

Professor S Brown MRc Harwell, oxford, UK

Professor Chris C Goodnow, Dr Edward M Bertram, Associate Professor Guna Karupiah, Dr Anselm Enders and Dr Katrina RandallSystems approach to Inflammation and Immunity

Professor R Ulevitch the scripps Research Institute, La Jolla, cA, Us Professor B Beutler University of texas southwestern Medical center, Dallas, texas, UsA Dr A Aderem and Institute for systems Biology, seattle, WA, Us Dr G Nolan Department of Microbiology and Immunology, stanford University, Palo Alto, cA, Us

Professor Chris C Goodnow and Dr Michael DobbieAustralian Phenomics Network Project: ES cell to Mouse Service

Associate Professor I Smyth Department of Biochemistry and Molecular Biology Faculty of Medicine, nursing and Health sciences, Monash University, clayton, VIc

Australian Phenomics Network Project: ENU Variant Collection

Professor B Kile chemical Biology Division, Walter and eliza Hall Institute of Medical Research, Melbourne, VIc

Professor S Foote Australian school of Advanced Medicine, Faculty of Human sciences, Macquarie University, sydney, nsW

Australian Phenomics Network Project: Mouse Pathology

Professor John Furness Autonomic and sensory neuroscience Laboratory, University of Melbourne, Melbourne, VIc

Professor N Dear Research and Biomedical services, south Australian Health and Medical Research Institute, Adelaide, sA

Australian Phenomics Network Project: Australian Phenome Bank Cryopreservation

Dr P Sharp Animal Resources centre, Murdoch University, canningvale, WA

Australian Phenomics Network Project: RNAi technologies

Professor K Simpson Gene Regulation Laboratory, Peter Maccallum cancer centre, Melbourne, VIc

Associate Professor L Winteringham Leukaemia Research Group, the Harry Perkins Institute of Medical Research, nedlands, WA

Dr R Dickins Molecular Medicine Division, Walter and eliza Hall Institute of Medical Research, Melbourne, VIc

Professor Chris C Goodnow, Mr Yogesh Jeelall, Professor Matthew C Cook, Dr T Dan Andrews and Mr Matthew FieldDeveloping novel deep sequencing methods for tracking human lymphoma mutations

Dr D Talaulikar canberra Hospital, canberra, Act

Professor Chris C Goodnow and Dr Ian ParishImaging proximal T cell signalling

Professor K Gaus centre for Vascular Research, University of new south Wales, sydney, nsW

Characterisation of an ENU mutant mouse line with a defect in gut peristalsis

Professor H Young and Professor J Furness Department of Anatomy and neuroscience, University of Melbourne, Melbourne, VIc

Professor Chris C Goodnow and Professor Carola G VinuesaImmunity and Infection Genomics Consortium

Dr R Cornall nuffield Department of clinical Medicine, oxford University, oxford, UK Professor J Bell the Weatherall Institute of Molecular Medicine, oxford University, oxford, UK Professor W Britton and Dr B Saunders centenary Institute of cancer Medicine and cell Biology, the University of sydney, sydney, nsW Professor M Lathrop national centre for Genotyping, evry, France

Professor Chris C Goodnow, Professor Carola G Vinuesa and Professor Matthew C CookMolecular and cellular studies of the adaptive immune response in health and disease

Professor C Mackay and Professor F Mackay-Fisson, Monash University, clayton, VIc Professor J Sprent, Emeritus Professor A Basten, Dr S Tangye, Dr R Brink and Dr Daniel Christ, Garvan Institute of Medical Research, sydney, nsW

Professor Chris C Goodnow, Dr Steve WInslade and Dr T Dan AndrewsFramework Data Sets

Mr A Gilbert Bioplatforms Australia, sydney, nsW

Professor Jill E GreadyCharacterization of natural variation of photosynthetic genes of potato for breeding improved cultivars with increase productivity and nutritional benefits

Dr D Ellis International Potato center, Lima, Peru

Development of ANU technology for the design of variant Rubisco proteins with improved catalytic activity

Professor JE Evans Research school of Biology, the Australian national University, canberra, Act Dr J van Rie and Dr A Gallé Bayer cropscience, Ghent, Belgium

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Annual Review 2014 37

Dr Rebecca HaddockRole of NOX-2 in obesity-related hypertension

Associate Professor GG Drummond Department of Pharmacology, Monash University, Melbourne, VIc

Role of immune cell derived NGF in hypertension

Dr A Vinh Department of Pharmacology, Monash University, Melbourne, VIc

Associate Professor Gavin HuttleyReconstruction of coral phylogeny

Dr S Forêt Research school of Biological sciences, the Australian national University, canberra, Act

Mathematical models of sequence divergence

Dr C Burden Mathematical sciences Institute, the Australian national University, canberra, Act

Annotation of novel genomes; and, identifying genes undergoing natural selection

Dr A Papanicolaou csIRo ecosystem sciences, canberra, Act

Development of a software library for genomic biology; numerous other projects related to the evolutionary dynamics of sequence divergence

Professor R Knight Department of chemistry and Biochemistry, University of colorado, Boulder, co, UsA

Development of Markov-process models to measure the influence of sequence-neighbourhoods on mutation dynamics

Associate Professor VB Yap Department of statistics and Applied Probability, national University of singapore, singapore

Associate Professor Gavin Huttley and Dr Åsa Pérez-Bercoff Understanding the genetic causes of virulence in fungal pathogens

Professor W Meyer Molecular Mycology Research Laboratory, centre for Infectious Disease and Microbiology, Westmead Millennium Institute, Westmead Hospital, sydney Medical school Westmead, the University of sydney, Westmead, nsW Professor H Nevalainen and Professor I Paulsen Department of chemistry and Biomolecular sciences, Macquarie University, sydney, nsW

Dr Andrew JamesMultimodal multifocal neuroimaging of human visual cortex

Dr S Vanni clinical neurosciences, neurology; University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Retinotopy constrained EEG source reconstruction without fMRI

Dr SA Inverso Wyss Institute, Harvard University, Boston, UsA

Mr Yogesh JeelallOmenn-like syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency

Professor S Ehl and Dr S Fuchs center for chronic Immunodeficiency (ccI), University Medical center and University of Freiburg, Freiburg, Germany

Dr Ben KaehlerGenetic distance for a general non-stationary Markov Substitution Process

Associate Professor VB Yap Department of statistics and Applied Probability, national University of singapore, singapore

Lessons from Nature

Dr H Trueman csIRo ecosystem sciences, canberra, Act

Associate Professor Guna Karupiah and Dr Geeta ChaudhriModulation of the immune response by virus-encoded cytokine homologs

Professor M Buller st Louis University, st Louis, Mo, Us Professor A Alcami centro de Biología Molecular severo ochoa, Madrid, spain

Induction of long-lived antiviral humoral immunity

Dr T Newsome school of Molecular Bioscience, University of sydney, sydney, nsW Professor R Brink Garvan Institute for Medical Research, sydney, nsW

Actin-based motility as a virulence mechanism and potential as an antiviral target

Dr T Newsome school of Molecular Bioscience, University of sydney, sydney, nsW

Pathophysiological significance of reverse signalling through membrane TNF

Professor A Alcami centro de Biología Molecular severo ochoa, Madrid, spain

Professor Trevor D LambEvolution of vertebrate photoreceptors

Professor D Hunt, Associate Professor N Hart, Dr WIL Davies and Professor SP Collin school of Animal Biology, University of Western Australia, Perth, WA

Responses of human cone photoreceptors measured from the electroretinogram

Dr O Mahroo Retinal service, Moorfields eye Hospital, London, UK

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38 the John curtin school of Medical Research

Associate Professor Brett LidburySystematic review and meta-analyses as a complementary technique to enhance predictions from pattern recognition involved in a novel animal replacement system

Professor M Ritkes-Hoitinga and Dr K Wever sYRcLe, Radboud University nijmegen, the netherlands

Pattern recognition in pathology data and in vitro validation of diagnostic data networks

Associate Professor T Badrick Faculty of Health sciences and Medicine, Bond University, Gold coast, QLD

Viral diseases and genetics of the host response

Associate Professor M Heise Department of Genetics, University of north carolina, chapel Hill, nc, UsA

Metabolomic profiles and clinical microbiology of ME-CFS

Dr Neil McGregor, Associate Professor P Gooley and C Armstrong Bio21 Institute and University of Melbourne, Melbourne, VIc

Immunology of ME-CFS

Professor S Marshall Griffith Health Institute, Griffith University, Gold coast, QLD

Biomedical and clinical study of ME-CFS patients

Dr D Lewis cFs Discovery, Donvale specialist Medical centre, Donvale, VIc

Professor Ted MaddessMultifocal visual evoked potentials

Dr S N Abdullah Raja Isteri Pengiran Anak saleha (RIPAs) Hospital, Bandar seri Begawan, Brunei

Structure and interactions of the squid retinal molecule

Professor Y Nagai and Dr M Kito Kokushikan University, tokyo, Japan

Causes of glaucoma

Professor WE Sponsel and Dr M Reilly Department of Biomedical engineering, University of texas, san Antonio, tX, UsA

Texture discrimination

Professor JD Victor Brain and Mind Research Institute and Department of neurology, cornell Weill Medical college, new York, nY, UsA

Diabetic retinopathy and macular degeneration

Professor C Nolan and Dr RW Essex AnU Medical school, the Australian national University, canberra, Act

Migraine, epilepsy and stroke

Professor C Lueck AnU Medical school, the Australian national University, canberra, Act

Dr Claudio A MastronardiMediators of inflammation

Dr J Fernandez-Solari Faculty of Dentistry, University of Buenos Aires, Buenos Aires city, Argentina and national council for scientific and technical Research (conIcet), Argentina P Barrionuevo Medical Research Institute (national Academy of Medical Research – conIcet), Buenos Aires city, Argentina

Dr Claudio A Mastronardi, Associate Professor Mauricio Arcos-Burgos and Dr Gilberto Paz-FilhoNeuroinflammation in Caspase-1-deficient mice

Dr M Zanoni University of Verona, Verona, Italy Professor J Licinio and Professor M-L Wong south Australian Health and Medical Research Institute and Flinders University of south Australia, Adelaide, sA

Dr Claudio A Mastronardi, Dr Gilberto Paz-Filho, Ms Belinda Whittle and Mr Robert TuningleyDried blood spot sampling for the measurement of HbA1c

Ms T Neeman statistical consulting Unit, the Australian national University, canberra, Act

Dr Maxim NekrasovCINDy – Chromosome Interaction Network DYnamics in adipose stem cells

Professor P Collas Department of Biochemistry, Institute of Basic Medical sciences, University of oslo,  oslo, norway

The role of Histone variants in formation of fear memory

Dr T Bredy Queensland Brain Institute, the University of Queensland,  Brisbane, QLD

Professor Christopher ParishRole of platelets in tumour metastasis

Professor B Chong school of Pathology, the University of new south Wales, sydney, nsW

Studies of immune thrombocytopenia

Professor B Chong school of Pathology, the University of new south Wales, sydney, nsW Professor L Khachigian centre for Vascular Research, the University of new south

Wales, sydney, nsW

Nuclear localisation of heparanase and other proteins

Professor R Stocker Department of Pathology, the University of sydney, sydney, nsW Professor L Khachigian centre for Vascular Research, the University of new south Wales, sydney, nsW Associate Professor S Rao Faculty of Applied science University of canberra, canberra, Act

Novel angiogenesis inhibitors

Dr P Karuso Department of chemistry and Biomolecular sciences, Macquarie University, sydney, nsW Dr M Kelso school of chemistry, University of Wollongong, Wollongong, nsW

Islet heparan sulfate and type I diabetes

Professor R Rodgers Department of obstetrics and Gynaecology, University of Adelaide, Adelaide, sA Professor T Kay st Vincent’s Institute, Melbourne, VIc

Targeted mistletoe tumour therapy

Associate Professor L Simson Faculty of Applied science University of canberra, canberra, Act

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Annual Review 2014 39

Development of heparan sulfate mimetics for type 1 diabetes treatment

Professor M von Itzstein Institute for Glycomics, Griffith University, Gold coast, QLD

Development of inhibitors of neutrophil extracellular traps

Professor M von Itzstein Institute for Glycomics, Griffith University, Gold coast, QLD

Dr Hardip PatelEffect of placental gene expression on cord blood during asthma

Associate Professor V Clifton Robinson Research Institute, University of Adelaide, Adelaide, sA

Physical mapping and assembly of the Pogona vitticeps genome

Professor A Georges and Associate Professor J Deakin Institute for Applied ecology, University of canberra, Bruce, Act

Dosage compensation of sex chromosomes in snakes

Dr P Waters Research school of Biology, the Australian national University, canberra, Act Dr D O’Meally Institute for Applied ecology, University of canberra, canberra, Act

Immune genes in the developing tammar wallaby (Macropus eugenii)

Associate Professor J Deakin Institute for Applied ecology, University of canberra, canberra, Act

Dr Hardip Patel, Dr Gilberto Paz-Filho, Claudio Mastronardi, Mr Angad Johar, Mr Aaron Chuah and Professor Mauricio Arcos-BurgosWhole exome sequencing of endocrine disorders: Translational studies in obesity and thyroid disorders.

Professor M Boguszewski and Professor C Boguszewski Universidade Federal do Paraná, Department of Pediatrics, Brazil Professor M-L Wong and Professor J Licinio south Australian Health and Medical Research Institute, Adelaide, sA

Dr Gilberto Paz-FilhoStudies on leptin deficiency, antidepressant-induced obesity, and mood disorders

Professor M-L Wong and Professor J Licinio south Australian Health and Medical Research Institute, Adelaide, sA

Congenital leptin deficiency

Professor T Delibasi Department of endocrinology, Hacettepe University, turkey

Adipose tissue biology

Professor S Bornstein and Dr M Ehrhart- Bornstein University of Dresden, Dresden, Germany

Pathology testing through dried blood spot

MyHealthTest Pty Ltd, Canberra, ACT

Leptin in Alzheimer’s disease

Dr W (Scoot) Kim, University of new south Wales, sydney, nsW

Dr Jason Potas670 nm light reduces allodynia following spinal cord injury

Associate Professor L Henderson Anatomy & Histology, school of Medical sciences, the University of sydney, sydney, nsW

New pharmacological agents that isolate individual fibre types in the peripheral nerve

Professor RT Sudo Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

Dr Jason Potas, Professor Greg Stuart and Professor Ted MaddessFunctional mapping of the dorsal column nucleus: A new approach to sensory pathway evaluation following spinal cord injury

Professor J Morley University of Western sydney, campbelltown, nsW, Dr S Redmond Graduate school of Biomedical engineering, the University of new south Wales, sydney, nsW

Mr Alvin PratamaMicroRNA-146a represses T follicular helper cell accumulation

Dr R Casellas Genomics and Immunity section, national Institute of Arthritis and Musculoskeletal and skin Diseases, national Institutes of Health, Bethesda, MD, UsA Dr A Hutloff chronic Immune Reactions Group, German Rheumatism Research centre Berlin, Berlin, Germany

Professor Thomas PreissThe human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells

Associate Professor G Hutvagner University of technology, sydney, nsW Associate Professor C Suter the Victor chang cardiac Research Institute, sydney, nsW Professor D Martin children’s Hospital oakland Research Institute, oakland, cA, UsA

The prevalence and roles of 5-methylcytosine in eukaryotic transcriptomes

Associate Professor C Suter the Victor chang cardiac Research Institute, sydney, nsW Professor S Clark and Professor J Mattick the Garvan Institute of Medical Research, sydney, nsW

Sequence diversity in the murine cardiomyocyte miRNA population

Associate Professor D Fatkin the Victor chang cardiac Research Institute, sydney, nsW

Exploring the role of microRNA and target processing variability in cardiac hypertrophy

Professor R Graham the Victor chang cardiac Research Institute, sydney, nsW

Dynamics of ribosome scanning and recycling revealed by steady-state translation profiling

Dr T Beilharz Monash University, Melbourne, VIc

Translational control of the EBV-encoded nuclear antigen, EBNA1

Dr J Tellam Queensland Institute of Medical Research, Brisbane, QLD

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40 the John curtin school of Medical Research

Developmental defects of the gastrointestinal tract caused by dysfunction of a RNA binding protein

Professor P Tam children’s Medical Research Institute, sydney, nsW

Exploring the interface between RNA, enzymes and metabolites in cardiomyocytes

Professor M Hentze european Molecular Biology Laboratory (eMBL), Heidelberg, Germany

The role of miRNAs in the generation of iPS cells

Professor A Nagy and Dr I Rogers Lunenfeld-tanenbaum Research Institute, toronto, on, canada Professor J-S Seo Genomic Medicine Institute (GMI), Medical Research center, seoul national University, seoul, Korea Professor J Rasko Gene and stem cell therapy Program, centenary Institute, camperdown, nsW Professor A Heck Biomolecular Mass spectrometry and Proteomics Group, Bijvoet center for Biomolecular Research and Utrecht Institute for Pharmaceutical sciences, Utrecht University, Utrecht, the netherlands Professor S Grimmond and Associate Professor C Wells Institute for Molecular Bioscience, the University of Queensland, Brisbane, QLD

Post-transcriptional control of gene expression in inflammation

Professor A Ostareck-Lederer and PD Dr D Ostareck University Hospital Aachen, RWtH Aachen University, Aachen, Germany

Professor Jan ProvisModelling and managing retinopathy of prematurity

Professor T Chan-Ling University of sydney, sydney, nsW

Professor Jan Provis and Dr Riccardo NatoliDifferential effects of 670 and 830nm red near infrared irradiation therapy

Professor S Dunlop and Associate Professor L Fitzgerald school of Animal Biology, University of Western Australia, Perth, WA

Dr Charani RanasingheHIV envelop antibody studies

Dr R Center Department of Microbiology and Immunology, the University of Melbourne, Melbourne, VIc

HIV-1 Pox-viral vaccine vectors

Dr D Boyle csIRo Livestock Industries, Australian Animal Health Laboratory, Geelong, VIc

HIV-1 mucosal vaccines and murine influenza-HIV-1 studies

Dr J Stambas Deakin University and csIRo Animal Health Laboratories, Geelong, VIc

TNF family members and immune responses to infection

Dr L Sedger school of Medical and Molecular Biosciences, the University of technology, sydney, nsW

Mucosal HIV, TB vaccines and CD8 T-cell avidity

Professor A Ramsay Gene therapy Program, Louisiana Vaccine centre, Louisiana state University Health sciences centre, new orleans, LA, UsA

Human HIV-specific T cell immunity & T cell avidity studies

Professor A Kelleher Immunovirology and Pathogenesis Program ncHecR, the University of new south Wales, sydney nsW and st Vincent’s centre for Applied Medical Research, sydney, nsW

HIV/SIV macaque vaccine studies

Professor S Kent and Dr R De Rose Department of Microbiology and Immunology, the University of Melbourne, Melbourne, VIc

Mucosal vaccine strategies against Chlamydia

Professor K Beagley Institute of Health and Biomedical Innovation, Queensland University of technology, Brisbane, QLD

Evaluation of a murine HIV challenge model

Professor A Suhrbier QIMR Berghofer Medical Research Institute, Brisbane, QLD

Dr Katrina RandallDOCK8 in T cells

Dr J Oliaro Peter Maccallum cancer centre, Melbourne, VIc

Dr Danny RangasamyToward repurposing antiviral drugs in the treatment of psoriasis

Professor J-P Molès, Institut national de la santé et de la recherche médicale, Montpellier, France

Exploring the role of L1 retrotransposon and Rad21 in CRC Cancer

Dr X Huiling Peter Maccallum cancer centre, Melbourne, VIc

Prognostic value of LINE-1 retrotransposon expression in breast cancer

Professor JE Dahlstrom Anatomical Pathology, Act Pathology, canberra Hospital and AnU Medical school, the Australian national University, canberra, Act

Analysis of epigenetic factors in mouse embryonic neural stem cells exposed to hyperglycemia

Professor ST Dheen Department of Anatomy, national University of singapore, singapore

Insertional mutagenesis system to identify epigenetic factors that control embryonic stem cells differentiation

Dr N Lenka national centre for cell science, Pune University campus, Ganeshkhind, Pune, India

Dr Daniel RyanStructural and functional analysis of a cancer-linked co-regulator complex

Professor J Mackay school of Molecular Biosciences, University of sydney, sydney, nsW

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription

Dr R Schneider Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et cellulaire (IGBMc), cnRs UMR, strasbourg, France

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Annual Review 2014 41

Dr Charmaine J SimeonovicHeparan sulfate expression in human pancreas, isolated human islets and islet transplants

Professor S Bornstein and Dr B Ludwig University clinic carl-Gustav-carus, technical University, Dresden, Germany

Heparan sulfate and heparanase expression in human pancreas

Clinical Associate Professor JD Wilson Department of endocrinology, canberra Hospital, canberra, Act

Dr Charmaine J Simeonovic, Ms S Dhounchak and Professor Christopher R ParishLoss of islet heparan sulfate in T2D in db/db mice

Professor T Biden and Dr R Laybutt Garvan Institute of Medical Research, sydney, nsW

Dr Charmaine J Simeonovic and Professor Christopher R ParishProtection of human islet beta cells by heparin and HS-mimetics

Professor T Kay, Dr H Thomas and Dr T Loudovaris Immunology and Diabetes Unit, st Vincent’s Institute, Melbourne, VIc Professor A Pugliese Diabetes Research Institute, Department of Medicine, Division of Diabetes, endocrinology and Metabolism, and Department of Microbiology and Immunology, University of Miami Miller school of Medicine, Miami, FL, UsA

Dr Zan-Min SongNon-enteric phenotype of Hirschsprung’s disease

Associate Professor D Croaker canberra Hospital, canberra, Act

Surgical intervention to rescue Hirschsprung’s disease in a rat model

Professor H Young and Professor J Furness Department of Anatomy and neuroscience, University of Melbourne, Melbourne, VIc

Associate Professor Christian StrickerShort-term dynamics in small networks

Dr M McDonnell Institute of telecommunications Research, University of south Australia, Adelaide, sA

Professor Greg J StuartAction potential initiation and interaction with inhibitory synaptic events

Professor M Häusser the Wolfson Institute for Biomedical Research, University college, London, UK

Dendritic activity and neuronal output during sensory perception

Dr L Palmer The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC

Professor David TremethickThe role of histone variants in modulating chromatin fibre dynamics

Dr K Luger Department of Biochemistry and Molecular Biology, colorado state University, Fort collins, co, UsA

The role of histone variants during spermatogenesis

Dr J Bowles Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD

Chromatin function in differentiation and cancer

Professor SA Grigoryev Department of Biochemistry and Molecular Biology, Milton s Hershey Medical centre, Penn state University college of Medicine, Hershey, PA, UsA

Regulation of promoter architecture: global changes in H2A.Z nucleosomes during differentiation and cancer

Dr JH Dennis Department of Biological science, the Florida state University, tallahassee, FL, UsA

Post translational modifications of histone variants and their role in transcription and pre mRNA splicing

Professor Dr U-M Bauer Institute for Molecular Biology and tumor Research, Philipps-University Marburg, Germany

Dr Krisztina ValterSlow-release treatment options in drug delivery to the retina

Professor S Bisti University of L’Aquila, L’Aquila, Italy

The effects of VCP treatment in the degenerative retina

Professor GJ Kotwal Kotwal Bioconsulting and st Kitts Medical school, WI, UsA Professor GJ Arason University of Iceland, Reykjavik, Iceland

Muller cell reactive gliosis and its control, using in vivo and in vitro models

Dr M Madigan save sight Institute, University of sydney, sydney, nsW and Department of optometry, University of nsW, sydney, nsW

670 nm red light treatment in retinal degenerations

Professor JT Eells University of Wisconsin, Milwaukee, WI, UsA

The effects on 670 nm light in retinal damage

Dr R Essex AnU Medical school, the Australian national University, canberra, Act

Oxygen-induced retinopathy and 670 nm light

Professor JE Dahlstrom Anatomical Pathology, Act Pathology, canberra Hospital and AnU Medical school, the Australian national University, canberra, Act Dr A Kent, Dr R Essex and Dr A-L Mohamed AnU Medical school, the Australian national University, canberra, Act and Act Health, the canberra Hospital, canberra, Act

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42 the John curtin school of Medical Research

Professor Carola G VinuesaOntogenic relationship between Tregs and follicular regulatory T cells

Professor A Liston, University of Leuven, Leuven, Belgium

B cell signatures in SLE

Professor V Pascual center for Inflammation and Autoimmune Diseases and center for Personalized Medicine, Baylor Institute, Dallas, tX, UsA

Role of Dopamine in antibody responses

Dr C Doglioni, Department of Pathology, san Raffaele Hospital, Milan, Italy

Single cell investigation of B cell differentiation and switching

Dr J Polo Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIc Dr K-M Toellner Institute of Immunology and Immunotherapy, college of Medical and Dental sciences, University of Birmingham, Birmingham, UK

MicroRna transcription and CRISPR/Cas9 DNA editing

Dr R Casellas Genomics and Immunity section, national Institute of Arthritis and Musculoskeletal and skin Diseases, national Institutes of Health, Bethesda, MD, UsA

Insights from Roquin crystal structure into miRNA/mRNA regulation

Dr J Babon the Walter and eliza Hall Institute for Medical Research, Melbourne, VIc

Professor Carola G Vinuesa, Professor Matthew Cook, Dr Dan Andrews, Mr Matthew Field and Dr Anselm EndersIdentification of novel and rare mutations in autoimmunity

Dr S Alexander the children’s Hospital at Westmead, Westmead, nsW Associate Professor D Fulcher Department of Immunopathology, the children’s Hospital at Westmead, Westmead, nsW Professor R Kitching Faculty of Medicine, nursing & Health sciences, Monash University, Melbourne, VIc Professor N Shen Jiao tong University, shanghai, china Professor E Morand school of clinical sciences, Monash Health and Faculty of Medicine, nursing & Health sciences, Monash University, Melbourne, VIc

Professor Ian G YoungRole of IL-3 receptor in myeloid leukaemia

Professor YZ Chen and Dr Y Wu Fujian Medical University, Fuzhou, china

Cytokine receptors

Dr J Murphy Molecular Medicine Division, Walter and eliza Hall Institute of Medical Research, Melbourne, VIc

Role of cytokines in allergic inflammation

Professor PS Foster school of Biomedical sciences and Pharmacy, University of newcastle, newcastle, nsW

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Annual Review 2014 43

AUstRALIAn PHenoMIcs FAcILItY coLLABoRAtIons

Systems Approach to Immunity and InflammationA project in its second 5 year funding cycle with the overall goal to identify and characterise novel regulators of the immune response to nIAID Priority Pathogens

Professor B Beutler University of texas southwestern Medical center, Dallas, tX, UsA Professor R Ulevitch the scripps Research Institute, La Jolla, cA, UsA Professor A Aderem Department of Immunology, University of Washington, seattle, WA, UsA and seattle Biomed, seattle, WA, UsA Professor G Nolan stanford University Palo Alto, cA, UsA

International Mouse Phenotyping Consortiumthe goal of the International Mouse Phenotyping consortium (IMPc) is to discover functional insight for every gene by generating and systematically phenotyping 20,000 knockout mouse strains. the APn missense mutation library is linked by gene to the IMPc and MGI JAX databases so that researchers from around the world can easily access the APn resource.

Professor S Brown (chair), Harwell MRc, Harwell science and Innovation campus oxfordshire, UK

Asian Mouse Mutagenesis and Resource Association-Asian Mouse Phenotyping Consortiumthe Asian Mouse Mutagenesis and Resource Association (AMMRA) is a collaborative group for the development, archiving/distribution, coordination of phenotyping and informatics of mutant mice in Asia.

Professor X Gao (President) national Resource center of Mutant Mice (nRcMM), nanjing University, china

Korean Mouse Phenotying ConsortiumProfessor JK Seong seoul national University, seoul, Korea Dr KT Nam Yonsei University, seoul, Korea

Hunter Genetics/ Rare VoicesHunter Genetics have used the exome discovery pipeline to identify rare variants.

Dr T Dudding, Dr B Kamien, Dr H Goel and Dr A Ronan Hunter Genetics, Waratah, nsW

Dementia Collaborative Research CentreAssociate Professor N Cherbuin Research school of Population Health, the Australian national University, canberra, Act, AnU

Mutagenetix A database of mutations and phenotypes induced by enU

Professor B Beutler University of texas southwestern Medical center, Dallas, tX, UsA

Framework Data SetsMr A Gilbert Bioplatforms Australia, sydney, nsW

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44 the John curtin school of Medical Research

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Annual Review 2014 45

Staff and Student ListsDepartment of Genome Biology

Department of Immunology

eccles Institute of neuroscience

Department of Molecular Bioscience

Department of Pathogens and Immunity

Australian Phenomics Facility

school Administration

school services

the AcRF Biomolecular Resource Facility

Genome Discovery Unit

Imaging and cytometry Facility

students

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46 the John curtin school of Medical Research

GenoMe BIoLoGY

Professor and Head of Departmenttremethick DJ, Bsc(Hons), (Usyd), PhD (MQ)

Departmental Administrator

stenhouse J, BA

Chromatin and Transcriptional Regulation Group

Professor and Leader

tremethick DJ, Bsc(Hons), (Usyd), PhD (MQ)

Research Fellow

soboleva t, Msc (MsU), PhD (MsU)

Postdoctoral Fellows

Domaschenz RM, Bsc(Hons) (Adel), PhD (cambridge) (from February) (casual)

nekrasov M, PhD (Heidelberg)

Ryan DP, Bsc(Hons) (Usyd), PhD

Visiting Fellows

cook AJL, BMedsci(Hons) (Usyd), PhD (Usyd)

Domaschenz RM, Bsc(Hons) (Adel), PhD (cambridge) (from February)

Hapel A (until september)

Parker B, Bsc (UQ), MBBs (UQ), PhD (Usyd) (from April)

shannon MF, Bsc(Hons), PhD (national University of Ireland)

Westman B, Bsc(Hons) (Usyd), PhD

Computational and Conceptual Biology Group

Professor and Leader

Gready Je, Bsc(Hons), PhD (Usyd), FRAcI

Senior Research Officers

cummins PL, Bsc(Hons), PhD (Usyd)

Kannappan B, Bsc (Madras), Msc, PhD (Pune)

Matthews PR, Bsc(Hons), PhD (AnU)

Research Officers

Kane H, PhD (part-time)

Postdoctoral Fellows

Poire R (from April)

Vassilieva t, Msc (novosibirsk)

Wallace MJ. Bsc (Wollongong) (until January)

Research Assistants

Delbridge M (part-time)

Howles P, BA (Usyd), Bsc (Adel), Bsc(Hons), PhD (part-time)

Mani-George A, Bsc, (Mahatma Gandhi, India), Msc (Bharathiar, India)

Miraghazadeh B (from April)

Visiting Fellows

Armarego W, PhD, Dsc (ULond), FRsc, FRAcI

Computational Genomics Group

Associate Professor and Leader

Huttley GA, Bsc(Hons) (MQ), PhD (Uc Riverside)

Postdoctoral Fellows

Kaehler B, Bsc (UnsW), Beng(Hons) UnsW, MQuantitative Finance (Uts), PhD

Pérez-Bercoff Å, PhD (Dublin)

Visiting Scholar

Zhu Y

Genome Diversity and Health Group

Professor and Leader

easteal s, Bsc(Hons) (st Andrews), MBA, PhD (Griffith)

Postdoctoral Fellow

Das D, Bsc(Hons) (Presidency college, Kolkata), Msc (Madurai Kamaraj), PhD (JncAsR, Bangalore)

Senior Technical Officer

tan X, Bsc (shandong), Msc (china Pharmaceutical)

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Annual Review 2014 47

National Center for Indigenous Genomics (from February)

Professor and Director

easteal s, Bsc(Hons) (st Andrews), MBA, PhD (Griffith)

Manager

Dobbie M, PhD (from september)

Research Officer

Brown K, PhD (from september)

Research Assistants

Pryce K, BAppsci (UHAn, nijmegen), Btech (Gilde college, Venlo)

Visiting Fellow

Kowal e, MBBs (UMelb), BA (UMelb), PhD (UMelb) (from June)

RNA Biology Group

Professor and Leader

Preiss t, Dipl chem (Philipps University Marburg Germany), PhD (newcastle upon tyne), Habil (Heidelberg)

Research Fellows

clancy JL, Bsc(Hons) (UnsW), PhD (UnsW)

Postdoctoral Fellows

Beveridge n, (Unewcastle) (until June)

Duan G, PhD (from March)

Kurscheid s, PhD (from December)

Liao Y, PhD (Uc Davis)

Patel H, BPharm, MBiotech, PhD

Senior Technical Officer

Pagler e, Bsc (santo tomas)

Visiting Fellows

Archer sK, Bsc(Hons), PhD (from september)

serra M, BA (tarkio), PhD (ohio U) (February – May)

shankar R (until July)

Translational Genomics Group

Associate Professor and Leader

Arcos-Burgos M, MD, PhD (University of cauca, colombia)

Research Fellows

Lidbury BA, Bsc(Hons) (newcastle), PhD (from February)

Mastronardi cA, PhD (University of Buenos Aires, Argentina) (from February)

Paz-Filho G, MD (Universidade Federal do Paraná, Brazil) (from February)

Research Assistant

cai Y, BMed (Bejing Medical University, china)

Visiting Fellows

Badrick t, BAppsci (QIt), Bsc (UQ), BA (UQ), MLit (UQ), MBA (UQ), PhD (QUt), PhD (UQ)

cummins t, Bsc(Hons) (Adel), PhD (UQ) (from August)

Richardson AM, BA(Hons) (Well), Mstats, PhD

Visiting Scholar

shang GF, Master of Medical Immunology (tongji Medical University, china)

silva Lara M-F, Bsc, Msc (from september)

School Visitor (Statistical Consulting Unit, ANU)

neeman t, BA (Harvard), MA, PhD (Virginia)

Departmental Visiting FellowsBarlin G, PhD, Dsc (Usyd), FRAcI

cox G, Bsc, PhD (UMelb), FAA

Denborough M, MD, chB (cape town), MD (UMelb), DPhil (oxon), Dsc (UMelb), FRcP

Morrison Je, Bsc (Usyd), Msc (UQ), DPhil (oxon), Dsc

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48 the John curtin school of Medical Research

IMMUnoLoGY

Professor and Head of DepartmentGoodnow cc, Bsc(Vet) (Usyd), BVsc(Hons) (Usyd), PhD (Usyd), FAA, FRs, nAs

Departmental Administrator

Weil etF

Cancer and Vascular Biology Group

Professor and Leader

Parish cR, BAgrsc (UMelb), PhD (UMelb)

Research Fellow

Quah B, Bsc, PhD

Postdoctoral Fellow

coupland L, Bsc(Hons), PhD, Rn

Visiting Fellows

chong G, MBBs (Hons), BMedsc (Monash) FRAcs, FRcs (c) FRcs (e), Diplomate, American Board of surgery (UsA)

cooper PD, Bsc (Hons) (ULond), PhD (ULond), Dsc (ULond)

Freeman c, Bsc(Hons) (Adel), PhD (Adel)

Hindmarsh eJ, Bsc(Hons) (Usyd), PhD

Li RW, MD (china Medical University), PhD (southern cross)

Price J, Bsc(Hons) (UMelb), PhD (UMelb)

Rao s, Bsc(Hons) (Keele), PhD (Kings college Lond)

staykova M, PhD (Usofia)

Warren Hs, Bsc(Hons), PhD (UQ)

Wu Z, Msc (UnsW), BM (Zhongshan Medical), PhD (from May)

Xin MY, BMed (shandong University) (until June)

Zhang DH, BMed (2nd Military Medical University, PR china)

Senior Technical Officer

Bezos A, Bsc (Usyd), Msc (Usyd)

Technical Officer

Browne A, BA (AnU), Dip ed (Une) (part-time)

School Visitor

Wang J, Msc (UnsW)

Editorial/Administrative Assistant

Parish B, Bsc (Madras), Bsc, Msc, GradDipcompstudies (Uc) (part-time)

Diabetes/Transplantation Immunobiology Laboratory

Fellow and Laboratory Leader

simeonovic cJ, Bsc(Hons), PhD

Postdoctoral Fellow

choong FJ, BBiotech(Hons), PhD

Visiting Fellows

Mccullagh P, MBBs (UMelb), DPhil (oxon), MRcP (Lond), MD (UMelb)

Wilson JD, Bsc(Hons), MBBch, BAo(Hons), MD (Queens, Belfast), MRcP (UK), FRAcP

Technical Officers

Brown D, AssDipAppPath (cIt) (casual)

Hamilton P, certificate II (Animal tech) (cIt) (part-time)

Popp sK, Bsc, AssDipAppsci (Biol) (cIt) (part-time)

Visiting Scholar

Hayashi K (until February)

Immunogenomics Group

Professor and Laboratory Head

Goodnow cc, BVsc(Hons) (Usyd), BscVet(Hons) (Usyd), PhD (Usyd), FAA, FRs, nAs

Laboratory Manager

townsend M, Pathtech cert (tAFe), AssDipAppPath (Bruce tAFe)

Bioinformatics Laboratory

Bioinformatics Fellow

Andrews tD, Bsc(Hons), PhD

Bioinformaticians

cho V, Bsc (Auck), PhD

Field M, Bsc (Biol)/Bsc (computer sci) (UBc)

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Annual Review 2014 49

Immune Tolerance and Signalling Laboratory

Professor and Laboratory Leader

Goodnow cc, BVsc (Usyd), BscVet(Hons) (Usyd), PhD (Usyd), FAA, FRs, nAs

Research Fellow

Bertram e, Bsc(Hons) (Adel), PhD (Adel)

CJ Martin Fellows

Parish IA, Bsc(Hons), PhD (WeHI)

Reed JH, Bsc(Hons) (Flinders), PhD (Flinders) (until november)

Research Fellows

Daley s, BVsc (UQ), DPhil (oxon)

Horikawa K, MD (chiba), PhD (tokyo)

srivastava M, Msc (Rewa), PhD (from January)

Research Technicians

Balakishnan B, Bsc(Hons)

Howard D, Bsc

Kaya Ms, Bsc (from February)

Law H, Bsc

Miosge L, Bsc(Hons), PhD

sontani Y, Bsc(Hons) (Murdoch), PhD

Laboratory Assistant

Kanazawa Y (casual)

Visiting Fellows

Randall K, MB (UnsW), Bs (UnsW), Bsc (UnsW), FRAcP, FRcPA, PhD

Reed JH, Bsc (Hons) (Flinders), PhD (Flinders) (from november)

Wilson A, Bsc(Hons) (Uc), Rn

Ramaciotti Immunization Genomics Group

Senior Research Fellow and Leader

enders A, MD, PhD (Freiburg)

Research Technician

Barthel n, DipBiol (Freie Univ, Berlin)

Infection and Immunity Group

Associate Professor and Leader

Karupiah G, Bsc(Hons), Msc (Malaya), PhD

Senior Technical Officer

eldi P, MBBs (India), Msc (UQ) (part-time)

Visiting Fellows

chaudhri G, Bsc(Hons), PhD

newsome tP, Bsc(Hons) (UMelb), PhD (Inst Molecular Pathology, Vienna) (until July)

Molecular Mucosal Vaccine Immunology Group

Fellow and Leader

Ranasinghe c, Bsc (Uni Rouen, France), MPhil (Uni colombo), PhD (UWA)

Resarch Fellow

Jackson R, Bsc (Hons) (Monash), PhD (edin)

Adjunct Fellow

sedger L, BAppsci(Hons) (Uts), PhD

Visiting Fellows

Mullbacher A, Bsc, Msc (Auck), PhD

stambas J, Bsc(Hons) (UMelb), PhD (UMelb)

Wijesundara D, Bsc (Hons), PhD (from March)

Visiting Technical Officers

Buchanan A, BHealthsci (Uc)

Ravichandran J, Bsc (India), Bsc(Hons) (UMelb) (part-time)

Worley M, Bsc

Visiting Scholar

el eryani G, Bsc

Translational Research Unit (joint with The Canberra Hospital)

Professor and Leader

cook M, MB, Bs (Usyd), FRAcP, FRcPA, PhD (Usyd), FFsc(RcPA)

Postdoctoral Fellow

sweet R, Bsc (UcLA), Msc (Yale), MPhil (Yale), PhD (Yale) (from september)

Research Assistants

chand R, Bsc(Hons) (UMelb)

Lam W, Bsc (Adel)

Wilson A, Bsc(Hons) (Uc), Rn (part-time)

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50 the John curtin school of Medical Research

eccLes InstItUte oF neURoscIence

Professor and Head stuart GJ, Bsc(Hons) (Monash), PhD (AnU), FAA

Departmental Administrator

Ursino D

Senior Technical Officer

Rodda GR, Ptc

Blood Vessel Group

Professor and Leader

Hill ce, Bsc(Hons), PhD, Dsc (UMelb)

Postdoctoral Fellow

Howitt L, Bsc (Usyd), PhD (UnsW) (until April)

Neuroimmunology & Cardiovascular Dysfunction Laboratory

Leader

Haddock Re, Bsc (Wollongong), Bsc(Hons), PhD (AnU)

Postdoctoral Fellow

Morton s, Bsc(Hons) (Massey), PhD (AnU) (July - December)

Cerebral Cortex Group

Professor and Leader

Bekkers JM, Bsc(Hons) (Griffith), Msc (Manchester), PhD (cambridge)

Postdoctoral Fellows

choy J, Bsc (UMs), PhD (until July)

suzuki n, Bsc (tsukuba), MMedsci (tsukuba), PhD (tokyo)

tantirigama M, Bsc(Hons) (otago), PhD (otago) (from February)

Research Assistant

tang s-M (until February)

Development of Visual Diagnostics of Eye Disease Group

Professor and Leader

Maddess t, Bsc(Hons) (UBc), PhD (AnU)

Research Fellows

Barbosa M, Bsc, Msc, PhD (são Paulo)

carle c, Bsc(Hons), PhD

sabeti F, Boptometry(Hons), Gradcertocuthera, PhD (until August)

Centre Managers

Rohan e (from July)

curran B, Bsc (AnU) (until August)

Technical Assistants

chia RH (until February) (casual)

Perera t (until February) (casual)

seah R (from november) (casual)

Visiting Fellows

Bell A (from July)

Farshid e

Hughes A

Mallikarjunan R

stronks c (from December)

Vidovic M

Xiang F (until July)

Adjunct Positions

Ibbotson M, Bsc, PhD

Penfold P

sarac Ö (from February)

University Fellow and Emeritus Professor

Levick W

Human Neuroimaging Group

Associate Professor and Leader

James Ac, Bsc(Hons)(Adelaide), PhD (AnU)

Neural Coding Group

Associate Professor and Leader

Arabzadeh e, MD, PhD

Postdoctoral Fellow

Adibi M, Bsc (Isfahan University of technology, Iran), Msc (Iran University of science and technology, tehran), PhD (UnsW)

Kheradpezhouh e, MD (shiraz, Iran), PhD (Adelaide) (from February)

Research Assistant

sizemova A

Neuronal Network Group

Associate Professor and Leader

stricker c, MD (Zurich), PhD (Bern)

Research Fellow

cowan AI, Bsc(Hons), PhD (AnU)

Neuronal Signalling Group

Professor and Leader

stuart GJ, Bsc (Hons) (Monash), PhD (AnU), FAA

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Annual Review 2014 51

Neurophotonics Laboratory

Leader

Daria V, PhD (osaka University)

Postdoctoral Fellow

choy J, Bsc (UMs), PhD (AnU) (from August)

Research Assistants

sane s (until August)

Go M (until september)

Gautiam V (from september)

Brain Development Laboratory

Leader

song Z-M, MMsc (Jiamusi), PhD (Flinders)

Neuronal Signalling Laboratory

Professor and Leader

stuart GJ, Bsc(Hons) (Monash), PhD (AnU), FAA

Postdoctoral Fellows

Bock t, PhD (AnU) (March - June)

Ikeda K, BA (Uc Boulder), PhD (AnU)

Jones s, PhD (AnU) (from April)

Keshavarzi s (until February)

Synaptic Mechanisms LaboratoryBillups B, Bsc(Hons) (UcL), Msc (Birmingham), MA (cambridge), PhD (UcL) (from september)

Retinal Cell Damage and Repair Group

Professor and Leader

Valter K, MD, PhD, Gradcert He

Research and Body Donation Co-ordinator

natoli R, Bsc(Hons) (Usyd), PhD (AnU)

Retinal Development and Aging Group

Professor and Leader

Provis J, Bsc(Hons) (UnsW), PhD (UnsW)

Postdoctoral Fellows

Bhat P, MBBs, FRAcP, PhD (from February)

Howitt L, Bsc (Usyd), PhD (UnsW) (May - november)

Rutar M, BMedsc(Hons), PhD (AnU)

Research and Body Donation Co-ordinator

natoli R, Bsc(Hons) (Usyd), PhD (AnU)

Visiting Fellow

Madigan M

Neural Control Systems GroupLeader

Potas JR, BMedsc(Hons) (Usyd), PhD (Usyd)

Visual Neuroscience Group

Professor and Leader

Lamb tD, Be (UMelb), scD (cambridge), FRs, FAA

University Fellow and Emeritus Professor

curtis DR, Ac, MBBs (UMelb), PhD, FRAcP, FAA, FRs

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52 the John curtin school of Medical Research

MoLecULAR BIoscIence

Professor and Head of Department Dulhunty AF, Bsc (Usyd), PhD, Dsc (UnsW)

Department Administrator

Ursino D

Biomolecular Interactions Group

Senior Research Fellow and Leader

casarotto MG, Bsc(Hons) (UMelb), PhD (UMelb) Postdoctoral Fellow

Joseph s, Bsc(Hons) (Usyd), PhD (Usyd) (from August)

Technical Officer

Aditya s, BBiotech(Hons) (AnU)

Visiting Fellows

Fan J, Bsc (Fudan), Msc (Fudan), PhD (Auck)

Lim Ps, BMedsci, PhD

Zafar A, PhD

Visitor

Rosenberg M, PhD

Cancer Metabolism and Genetics Group

Fellow and Leader

Blackburn A, Bsc(Hons) (UnsW), PhD

Laboratory Technician

Rooke M, BMedsci (Pharm sci) (csU)

Cytokine Molecular Biology and Signalling Group

Professor and Leader

Young IG, Msc (UMelb), PhD

Postdoctoral Fellow

Abdus F, Bsc(Hons) (Bangladesh), Msc (UWsyd), PhD

Visiting Fellows

chen J, Bsc, (china), MMed (china), PhD (Flinders)

Murphy J, Bsc, PhD

Visiting Scholar

Yong W, MMed (china), MD (china)

Technical Officers

Dai J, Bsc, MBiotech

ewens c

Wen B, MB (china), Msc (china), PhD

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Annual Review 2014 53

Epigenetics and Genome Stability Group

Fellow and Leader

Rangasamy D, Msc, Mtech (India), PhD (UK)

Molecular Genetics Group

Professor and Leader

Board PG, Bsc(Hons), PhD (Une)

Postdoctoral Fellow

theodoratos A, Bsc(Hons) (Usyd) PhD

Visiting Fellows

Baker R, Bsc(Hons)(UnsW), PhD

coggan M

Dahlstrom J, MBBs(Hons), FPAc, PhD, FRcPA, FFoP, FFsc, Gradcertedst (Highered), sFHeA

Hayes Mt, Bsc (Usyd), Msc (Usyd), Diped (tert) (Une), PhD (QUt) (until october)

Lee e, Bsc(Hons), PhD

Liu D, PhD (Usyd) (from March)

Ramshaw IA, Msc (Brunel), PhD

shield A, BBiotech(Hons) (Flinders), PhD (Flinders)

Visiting Scholar takemura K, PhD

Laboratory Technicians

cappello J, Bsc (Uc), AD AppsciAnsci (cIt)

tummala P, Bsc (nagarjuna U) Msc (MsU), PhD (oU)

Muscle Research Group

Professor and Leader

Dulhunty AF, Bsc (Usyd), PhD, Dsc (UnsW)

Senior Research Advisor

Gallant e, PhD (Minnesota)

Postdoctoral Fellows

Karunasekara YA, MD (UssR), PhD (until April)

Visiting Fellow

Karunasekara YA, MD (UssR), PhD (from April)

salvage s, PhD (oxford)

tierney L, Bsc, Msc (otago), PhD

Senior Technical Officer

Pace s, Bsc (Uts)

Laboratory Technicians

stivala J

thekkedam c, BscBiotech(Hons) (Wollongong)

Stem Cells and Gene Targeting Group

Professor and Leader

Matthaei KI, Bsc(Hons) (UnsW), PhD

Visiting Fellows

Barharvand H

Frese M, Bsc (osnabrück), PhD (Freiburg)

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54 the John curtin school of Medical Research

PAtHoGens AnD IMMUnItY

Professor and Head of DepartmentVinuesa cG, LMs(MBBs) (Madrid), DRcoG (Lond), Msc, PhD (Birmingham)

Departmental Administrator

Morales D

Humoral Immunity and Autoimmunity Group

Elizabeth Blackburn NHMRC Research Fellow

Vinuesa cG, LMs(MBBs) (Madrid), DRcoG (Lond), Msc, PhD (Birmingham)

CJ Martin Fellow

ellyard J, BAs, Bsc(Hons), PhD

Post-doctoral Fellows

Athanasopoulos V, Bsc (Hons), PhD (UMelb)

Duan t, MBBs (nanjing), PhD (until March)

sweet R, Bsc (UcLA), Msc (Yale), MPhil (Yale), PhD (Yale) (until August)

Visiting Fellows

Good M, Ao, Bsc, MBBs, PhD, MD, Dsc

Walter G, BA (cantab), MBchB (edinburgh), MRcP (UK), MD

Laboratory Technical Staff

capello J (from February)

Williams n

Research Assistant

Lee sK, MBiotech (Flinders) (April - october)

Inflammatory T Cell Responses Group (from July)

Research Fellow and Leader

Breustle A, PhD (from July)

Malaria and Infectious Disease Group (from October)

Professor and Leader

Foote s, MBBs, Dsc, FFsc (RcPA), FAHMs, Ftse

Research Fellow

McMorran B, Bsc(Hons), PhD (otago)(from December)

Malaria Immunology Group

Group Leader

cockburn I, MBiochem (oxon), PhD (edin)

Postdoctoral Fellow

Dups J, BVsc (UQ), PhD (UMelb) (from october)

Laboratory Technician

cai Y, BMed (Beijing Med) (from september)

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Annual Review 2014 55

AUstRALIAn PHenoMIcs FAcILItY AnD AnIMAL seRVIces

Director

Winslade sL, BA(Hons) (Une), PhD (Une)

Head of Animal Services

Fowler s, Bsc, BVMs (Murdoch)

Head of International Programs

Bertram e, Bsc(Hons) (Adel), PhD (Adel)

Scientific Business Manager

Dobbie Ms, BAppsc (Uts), Msc (Usyd), PhD (Lond)

Liaison Officer

Hewitt L, BMedsci (Uc)

Departmental Administrator

o’Keefe R

Scientific Programs

Scientific Programs Manager

Balakishnan B, Bsc(Hons)

Scientific Project Coordinators

Kofler J, DipAntech (cIt), Bsc

Morris L, Bsc(Hons) (Lond), Msc(Res) (edin), PhD (edin)

osborne A, BAnimalsci (JcU) (from July)

tunningley R, BMedsci

Scientific Project Technicians

Kan W, BBioMedsc (Hons) (Monash)

Lorenzo A, Bsc Biol (RP)

Mei Y (from April)

nasreen M (from March)

Australian Phenome Bank

Phenome Bank Curator

Read sH, Bsc(Hons) (Adel), PhD (Adel)

Cryopreservation and IVF Coordinator

du Boulay c, cert IV Vet nursing (cIt), Dip Appsci (cIt)

IVF and Cryopreservation Technician

thomsen n, Bsc(Hons) (UQ)

Quarantine Coordinator

Ross n, RLAt, Dip Appsci Animal tech (cIt)

Quarantine Technician

Hunt B

Information Technology

IT Manager

Wu P, Bsc(Hons), Bcompsci (canada)

IT Officers

Hongyu M, Bcompsci (china), Mswe (singapore)

Jiang M, Bcompsci (china), Mcomp (AnU), MIs (AnU), MBA candidate BIs (AnU)

tan J, Bcompsci (UA), Mcomp (UA)

Quinn G

shaw F

Genomics

Head of Genomics Research

Whittle B, Bsc(Hons)

Genomics Coordinators

Mann D, Bsc(Hons) (until october)

stefanovic t, BMedsc(Hons) (from october)

Zhang Y, Bsc, Msc (china)

Genomics Technical Officers

Armstrong M

Fitzgerald L, AssocDip Animal sci, cert IV Vet nursing (cIt)

Gao J, Bsc (china), MBiotech(Hons)

Liang R, Bsc, Msc (china)

Liu M, Bsc, Msc (china)

Palkova A, BBus (QUt), Bsc(Hons) (UQ)

Patel V

sakthivel G, BMedsci(Hons)

sayeed s, Bsc, Msc (Bangladesh), PhD (UK)

schoning J, BBiotech(Hons)

shang G (from March)

Animal Services

Animal Services Managers

Bowditch K

clydesdale M

Animal Services Coordinators

Barker A

Bolton s-M

Burke H, BBehavestudies (swinburne)

Gooding D, cert IV training and Assessment, Dip Animal technology (cIt)

Technicians

Allsop I, cert III Animal tech (cIt)

Aquino W, BAnisci (UWs)

Arthur M

Barker A

Boljun M

Burke J

Burt K (from June)

Bush t

caston K (from June)

chau K, Dip Animal tech (cIt) (until December)

cook A

corby R (from June)

cover G

Facchin D (from June)

Fowlie c

Haas P

Hamilton R

Hartley s

Jarvis L

Kaya Ms, Bsc (Unewcastle)

Lin Q

Lind F (until December)

Lockley J

Lorenzi L

Milne R (from June)

McGowan A

McWilliam D

Pobjie A, DipAnitech (cIt)

Portway c

Prewett B

sibley B

sparrow M

spencer c

steen e

talbot s, Dip Appsci (Animal tech) (cIt)

Vithanage U

Watson D

Young s

Building Maintenance Supervisor

Hosking A

Storeperson/Maintenance Assistant

smith D

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56 the John curtin school of Medical Research

scHooL seRVIces

scHooL ADMInIstRAtIon

DirectorateDirector

Parish cR, BAgrsc (UMelb), PhD (UMelb) (until october)

Foote sJ, MBBs, Dsc, FFsc (RcPA), FAHMs, Ftse (from october)

Deputy Director

Bekkers JM, Bsc(Hons) (Griffith), Msc (Manchester), PhD (cambridge)

Business Manager

cousins M

Executive Officer to the Director

Flowers c (from october)

Executive Assistant to Director

Vitler L (until october)

Reception

Azzopardi n

Outreach and Communications Unit

Manager

nicol MJ, Bsc (Wollongong), Bsc(Hons), PhD (AnU)

Senior Multimedia Officer

edwards K, Photcert

Education

Associate Director Education and Medical Sciences Graduate Convener

cowan A, Bsc(Hons), PhD, GradcertHe

PurchasingDowling e (January-February)

townsend K (from March)

Wozniak P, cert IV GPc

Safety & Training

Work Place Health and Safety Officer

Hayes Mt, Bsc (Usyd), Msc (Usyd), Diped (tert) (Une), PhD (QUt) (until november)

Mann D, Bsc(Hons) AnU (from november)

Work Place Health and Safety Assistant

Gilmartin L, cert III Lab skills (cIt) (part-time)

Facilities

Manager

coombes D

Facilities Officer

Kynoch M

Operations Assistant

ciuffetelli L

Administrative Assistant

Dowling e

Senior Storeperson

talbot A

Media & Washup

Manager

coombes D

Supervisor and Technical Officer

Gilmartin L, cert III Lab skills (cIt)

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Annual Review 2014 57

tHe AcRF BIoMoLecULAR ResoURce FAcILItY, GenoMe DIscoVeRY UnIt AnD IMAGInG AnD cYtoMetRY FAcILItYACRF Biomolecular Resource FacilityManager

Palmer s, Bsc(Hons) (AnU), MBA (tech Management) (chifley Business school)

Technical Specialist

Milburn P, Bsc(Hons), PhD (sheffield)

Genomics Team

cripps t, Bsc(Hons)

Higgins A, cBLt (UsQ)

ohms s, MBchB, Me, PhD (Auck)

Peng K, PhD (Wuhan)

Zhang K, Msc (Fudan), PhD

Genome Discovery Unit

Manager

Kaehler B, PhD

Computational Specialists

Buckley B, BA(Hons) (UQ)

chuah A, Beng(Hons) (nUs)

Patel H, BPharm, MBiotech, PhD

Research Fellow

Parker B, Bsc (UQ), MBBs (UQ), PhD (Usyd) (until April)

Bioinformatician

Jack c, Bsc (Wellington)

Honorary Visitor

Gock A, BAppsci (csU) (until February)

Research Fellow

Parker B, Bsc (UQ), MBBs (UQ), PhD (Usyd) (until May)

Imaging and Cytometry Facility (ICF)

Manager

Gillespie cM, GradcertMic (Usyd)

Histologist

Prins As, BAppsci (RMIt)

Flow Cytometry Specialist

Vohra H, Msc(Hons) (Punjab), PhD (PGIMeR)

Flow Cytometry and Microscopy Operator

Devoy M, Bsc(Hons)

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58 the John curtin school of Medical Research

stUDents

PhD StudentsAchuthan s

Agahari F, Bsc(Hons) (Japan)

Alfaro A (from May)

Ali e

Al Rumaih Z, Msc(Biotech)

Alshekaili J, MD

Andrews s

Anuar nD, Bsc(Hons), Msc (Malaysia)

Azad B (from February)

Bell s, Bsc(Hons)

Bergmann H, D.Vet.Med. (Hanover, Germany)

Bock t, Bsc(Hons) (until March)

chaston D, Bsc(Hons)

Dalefield M

Da silva e, MBBs, BA, FRAcP, FRcPA

Dave P

Dhounchak s, BBiotech, MBiotech (Research) (from March)

eldi P, MBBs (India) Msc (UQ)

Feakes D

Fernando n

Flower c, Bsc (UtAs)

Galgamuwe R, MBBs, Msc (sri Lanka)

Gang B, BBiomedsci (otago)

Go M-A, Bsc, Msc (U Philippines)

Gonzalez P

Han s-Y Bsc(Hons)

Hausner s

Hu Daniel, BMedsci(Hons) (Usyd)

Hu Di

Huang H, BBiomedsci(Hons) (otago)

Hussain M, Bsc(Hons)

Hynes c, Bsc(Hons)

Jeelall Y, BBiomedsci(Hons) (UMelb)

Jiang s, MBBs FRAcP

Jiao H

Johnson-saliba M, PhD

Jones s, BMedsci(Hons) (UnsW) (until March)

Khanna M, BBiomedsci(Hons) (Victoria, Wellington)

Kingston Z

Kolic M

Lee c

Lee e, Bsc, Msc (Uc)

Lee s, BBiomedsci, Msc (Auck)

Lehman s

Li J, BMedsci(Hons) (until november)

Li L, Bsc (Biotech)

Lu Y-Z

Mei Y, Bsc(Hons) (ottawa)

Menon D, BBiotech, MBiotech

Mishra A, Bsc, Msc (nepal)

Mohan A, Btech (India)

Morse A

Morton s, Bsc(Hons)

newman s, Bsc(Hons)

nunez L (from April)

Papa I, MPhil (Milan)

Pratama A, PhB(Hons)

Racic t (from February)

Ramiscal R, Bsc (UnsW), Bsc(Hons)

Ratnadikawara M

Rebbeck R, BMedsci(Hons)

Richardson s, Bsc(Hons)

Robertson J, Bsc(Adv)(Hons)

Roco J

Rudinski s, Bsc(Hons)

sabouri Z, MD (until november)

samarasinghe K

saxena K, BBiotech

seamons J

shafik A

shen Q, MBiochem

sibritt t, Bsc(Hons)

simon Davis DA, Bsc(Hons) (Adel)

singh M, Bsc(Hons) (otago)

sinha D, Bsc, Msc (India)

soetanto R

srivastava M, Msc (Rewa)

tan X, Bsc, Msc

tran L

trivedi s, BBiotech, MBiotech (Research)

Velez J

Wagle M, Bsc(Hons) (from February)

Wang J, BBiomedsc(Hons) (UMelb), Bsc(Hons) (UMelb)

Welham Z, BAppsci(Hons) (from May)

Wijesundara D, BBiotech(Hons) (until March)

Willemse H, Bsc(Hons), Msc

Wium e, BMedsci(Hons)

Yabas M, MPhil (until August)

Yang H

Yap J, MBiotech(Hons)

Yoon J, Bsc, Msc (Pukyong nat Univ, Korea)

Zhu Y (from May)

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Annual Review 2014 59

MPhil StudentsJohar A

Li Z, Bsc (Beijing Inst technology)

Honours StudentsAbd Hamid M, Bsc (from February)

Ash o (until June)

chen t

chia RX

chu-tan J

D’Arcy n

Ferguson L, Bsc (from February)

Fernandez P

Hall s

Kwong KXM, Bsc (from July)

Lambe s, Bsc (from February)

Li F-J, Bsc (from February)

Loutit A

nailer L

ng A, Bsc (from July)

nguyen n (from July)

Roper e

Perotti s, Bsc (from February)

sarraf s

silva cayetano A

sparbier c

tam KL, Bsc (until July)

tay Y (from July)

townsend D, Bsc (from July)

Wilson A

Wu Y (from July)

Young G

MNeuroscience Students Balodis R

Dean H

Dong P

espinoza-oyarce D

Gotsis s

Hadad R

Haque F

Kaide J

owens-Walton c

Ravi I

scetrine A

senga s

teasdale H

Zhang t

MTranslational Medicine StudentsAlexander P

Barry P

Dunn c

Forster R

Rodriguez A

Research PlacementKherlopian A

Lo L

Visiting ScholarsBai B

Hayashi K, (until February)

Gharaei s

Fazlali Z (from April)

see M

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60 the John curtin school of Medical Research

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Annual Review 2014 61

Publications, Presentations and Community Outreach 2014Publications: A Full list of publications from JcsMR staff and students in 2014, including:

• peer reviewed journal articles • reviews • short communications • book chapters

Presentations made by JcsMR staff and students at local, national and international research institutions, conferences and workshops throughout the year:

• Staff presentations • Student presentations

staff and students of the school continue to sit on numerous editorial boards, to assist with national and international granting bodies as expert assessors, and to belong to many scientific societies. they are also involved with community activities outside the school, some of which are listed.

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62 the John curtin school of Medical Research

PUBLIcAtIons

Abdullah, sn, sanderson, GF, James, AC, Vaegan and Maddess, T (2014) Visual evoked potential and psycho-physical contrast thresholds in glaucoma. Documenta Ophthalmologica 128(2):111-120

Adibi, M, McDonald, Js, clifford, cWG and Arabzadeh, E (2014) Population decoding in rat barrel cortex: optimizing the linear readout of correlated population responses. PLoS Computational Biology 10(1):e1003415

Ali, en, Maddess, T, James, AC, Voicu, c and Lueck, cJ (2014) Pupillary response to sparse multifocal stimuli in multiple sclerosis patients. Multiple Sclerosis Journal 20(7):854-861

Altin, JA, Daley, SR, Howitt, J, Rickards, HJ, Batkin, AK, Horikawa, K, Prasad, sJ, nelms, KA, Kumar, s, Wu, Lc, tan, ss, Cook, MC and Goodnow, CC (2014) ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding cD4(+) t cells. Proceedings of the National Academy of Sciences of the United States of America 111(6):2067-2074

Andoniou, ce, sutton, VR, Wikstrom, Me, Fleming, P, thia, KYt, Matthews, AY, Kaiserman, D, schuster, Is, coudert, JD, Eldi, P, Chaudhri, G, Karupiah, G, Bird, PI, trapani, JA and Degli-esposti, MA (2014) A natural genetic variant of granzyme B confers lethality to a common viral infection. PLoS Pathogens 10(12):4526-4526

Arabzadeh, E, clifford, cW, Harris, JA, Mahns, DA, Macefield, VG and Birznieks, I (2014) single tactile afferents outperform human subjects in a vibrotac-tile intensity discrimination task. Journal of Neurophysiology 112(10):2382-2387

Archer, SK, Shirokikh, NE and Preiss, T (2014) selective and flexible depletion of problematic sequences from RnA-seq libraries at the cDnA stage. BMC Genomics 15:401

Assareh, AA, Mather, KA, crawford, JD, Wen, W, Anstey, KJ, Easteal, S, Tan, X, Mack, HA, Kwok, JB, schofield, PR and sachdev, Ps (2014) Renin-angiotensin system genetic polymorphisms and brain white matter lesions in older Australians. American Journal of Hypertension 27(9):1191-1198

Babb, R, chan, J, Khairat, Je, Furuya, Y and Alsharifi, M (2014) Gamma-irradiated influenza A virus provides adjuvant activity to a co-administered poorly immunogenic sFV vaccine in mice. Frontiers in Immunology 5:267

Barbosa, M and James, AC (2014) Joint iris boundary detection and fit: a real-time method for accurate pupil tracking. Biomedical Optics Express 5(8):2458-2470

Barbosa, M, Natoli, R, Valter, K, Provis, P and Maddess, T (2014) Integral-geometry characterization of photobiomodulation effects on retinal vessel morphology. Biomedical Optics Express 5(7):2317-2332.

Battefeld, A, tran, Bt, Gavrilis, J, cooper, ec and Kole, MH (2014) Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons. Journal of Neuroscience 34(10):3719-3732

Bell, A (2014) constructive interference of tonal infrasound from synchronised wind farm turbines: evidence and implications. Acoustics Australia 42(3):188-194

Bell, A (2014) Annoyance from wind turbines: role of the middle ear muscles. Acoustics Australia 42(1):57

Berghoff, As, Kiesel, B, Widhalm, G, Rajky, o, Ricken, G, Wöhrer, A, Dieckmann, K, Filipits, M, Brandstetter, A, Weller, M, Kurscheid, S, Hegi, Me, Zielinski, cc, Marosi, c, Hainfellner, JA, Preusser, M and Wick W (2014) Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma. Neuro-Oncology 0:1–12

Bhat, P, Leggatt, G, Matthaei, KI and Frazer, IH (2014) the kinematics of cytotoxic lymphocytes influence their ability to kill target cells. PLoS ONE 9(5):1-11

Bird, MK, Lohmann P, West B, Brown RM, Kirchhoff J, Raymond, CR and Lawrence, AJ (2014) the mGlu5 receptor regulates extinction of cocaine-driven behaviours. Drug and Alcohol Dependence 137:83-9

Bogdani, M, Korpos, e, Simeonovic, CJ, Parish, CR, sorokin, L, and Wight, tn (2014) extracellular matrix components in the pathogenesis of type 1 diabetes. Current Diabetes Reports 14(12):552

Branca, RM, orre, LM, Johansson, HJ, Granholm, V, Huss, M, Pérez-Bercoff, Å, Forshed, J, Käll, L and Lehtiö, J (2014) HiRIeF Lc-Ms enables deep proteome coverage and unbiased proteogenomics.Nature Methods: Techniques for life scientists and chemists 11(1):59-62

Brenner, D, Brüstle, A, Lin, GH, Lang, PA, Duncan, Gs, Knobbe-thomsen, cB, st Paul, M, Reardon, c, tusche, MW, snow, B, Hamilton, sR, Pfefferle, A,

Gilani, so, ohashi, Ps, Lang, Ks and Mak, tW (2014) toso controls encephalitogenic immune responses by dendritic cells and regulatory t cells. Proceedings of the National Academy of Sciences of the United States of America 111(3):1060-5

Brizuela, M, Huang, HM, smith, c, Burgio, G, Foote, SJ and McMorran, BJ (2014) treatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquine. PLoS One 9(4):e92411

Bull, KR, Mason, t, Rimmer, AJ, crockford, tL, silver, KL, Bouriez-Jones, t, Hough, tA, chaudhry, s, Roberts, IsD, Goodnow, CC and cornall, RJ (2014) next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson’s syndrome. Journal of Pathology 233(1):18-26

Bunce, D, Bielak, AAM, Anstey, KJ, cherbuin, n, Batterham, PJ and Easteal, S (2014) APoe Genotype and cognitive change in Young, Middle-Aged, and older Adults Living in the community. Journals of Gerontology Series A-Biological Sciences and Medical Sciences 69(4):379-386

Burke, LK, Doslikova, B, D’Agostino, G, Garfield, As, Farooq, G, Burdakov, D, Low, MJ, Rubinstein, M, evans, ML, Billups, B and Heisler, LK (2014) 5-Ht obesity medication efficacy via PoMc activation is maintained during aging. Endocrinology 155(10):3732-3738

Carle, CF, James, AC, Kolic, M, essex, RW and Maddess, T (2014) Luminance and color variant pupillographic perimetry in glaucoma. Clinical and Experimental Ophthalmology 42(9):815-824

carr, PD, Ewens, CL, Dai, J, ollis, DL, Murphy, JM, Jackson, cJ and Young, IG (2014) crystal structure of the mouse interleukin-3 beta-receptor: Insights into interleukin-3 binding and receptor activation. Biochemical Journal 463:393-403

Chaston, DJ, Haddock, RE, Howitt, L, Morton, SK, Brown, RD, Matthaei, KI and Hill, CE (2014) Perturbation of chemical coupling by an endothelial cx40 mutant attenuates endothelium dependent vasodilation by Kca channels and elevates blood pressure in mice.  Pflugers Archiv-European Journal of Physiology 467(9):1997-2009

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Annual Review 2014 63

Chen, L, Dahlstrom, JE and Rangasamy, D (2014) Differential DnA methylation patterns in endo-siRnAs mediated silencing of LIne-1 retrotransposons. Methods in Molecular Biology 1173:169-180

chen, W, Foo, ss, Li, RW, smith, Pn and Mahalingam, s (2014) osteoblasts from osteoarthritis patients show enhanced susceptibility to Ross River virus infection associated with delayed type I interferon responses. Virology Journal 11(1):189

chen, WQ, Foo, ss, Rulli, ne, taylor, A, sheng, Kc, Herrero, LJ, Herring, BL, Lidbury, BA, Li, RW, Walsh, nc, sims, nA, smith, Pn and Mahalingam, s (2014) Arthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss. Proceedings of the National Academy of Sciences of the United States of America 111(16):6040-6045

chen, XB, nisbet, DR, Li, RW, smith, Pn, Abbott, tB, easton, MA, Zhang, DH, Birbilis, n (2014) controlling initial biodegradation of magnesium by a biocompatible strontium phosphate conversion coating. Acta Biomaterialia 10(3):1463-74

chew, GYJ, Gatenby, PA, Mercan, s, De Malmanche, t, Adelstein, s, Garsia, R, Hissaria, P, French, MA, Riminton, Ds, Fulcher, DA, scorza, R, D’Alfonso, s, Doria, A, Rúa Figueroa, I, cervera, R, Vasconcelos, c, Martins, B, Alarcón Riquelme, M, Vinuesa, CG and Cook, MC (2014) 2tnFRsF13B Variants in sLe and Immunodeficiency. Journal of Clinical & Cellular Immunology 5(4):1-8

Cho, V, Mei, Y, sanny, A, chan, s, Enders, A, Bertram, EM, tan, A, Goodnow, CC and Andrews, TD (2014) the RnA-binding protein hnRnPLL induces a t cell alternative splicing program delineated by differential intron retention in polyadenylated RnA. Genome Biology 15(1):R26

Clancy, JL, Patel, HR, Hussein, sM, tonge, PD, cloonan, n, corso, AJ, Li, M, Lee, Ds, shin, JY, Wong, JJ, Bailey, cG, Benevento, M, Munoz, J, Chuah, A, Wood, D, Rasko, Je, Heck, AJ, Grimmond, sM, Rogers, IM, seo, Js, Wells, cA, Puri, Mc, nagy, A and Preiss T (2014) small RnA changes en route to distinct cellular states of induced pluripotency. Nature Communications 5:5522

Cockburn, IA, tse, sW and Zavala, F (2014) cD8(+) t cells eliminate liver-stage Plasmodium berghei parasites without

detectable bystander effect. Infection and Immunity 82(4):1460-1464

Cooper, PD, Barclay, tG, Ginic-Markovic, M and Petrovsky, n (2014) Gamma ray sterilization of delta inulin adjuvant particles (Advax (tM)) makes minor, partly reversible structural changes without affecting adjuvant activity. Vaccine 32(5):552-557

Coupland, LA and Parish, CR (2014) Platelets, selectins and the control of tumour metastasis. Seminars in Oncology 41(3):422-434

Das, D, cherbuin, n, Easteal, S and Anstey, KJ (2014) Attention deficit/hyperactivity disorder symptoms and cognitive abilities in the late-life cohort of the PAtH through Life study. PLOS One 9(1):e86552

Das, D, Tan, XY, Bielak, AAM, cherbuin, n, Easteal, S and Anstey, KJ (2014) cognitive ability, intra-individual variability, and common genetic variants of catechol-o-Methyltransferase and brain-derived neurotrophic factor: A longitudinal study in a population-based sample of older adults. Psychology and Ageing 29(2):393-403

Delghingaro-Augusto, V, Madad, L, chandra, A, Simeonovic, CJ, Dahlstrom, Je and nolan, cJ (2014) Islet inflammation, hemosiderosis, and fibrosis in intrauterine growth-restricted and high fat-fed sprague-Dawley rats. American Journal of Pathology 184(5):1446-1457.

De Luca, A, Laugier, s, Tea, I, Robins, RJ, saulnier, P-J, torremocha, F, Piguel, X, Marechaude, R, Hankard, R and Hadjadj, s (2014) Impact on bulk 15n natural isotopic abundance in hair of kidney function in type 2 diabetic nephropathy. E-SPEN Journal 9(6):204-209

DeRose, Kent, sJ and Ranasinghe C (2014) Prime-boost vaccination: Impact on the HIV vaccine field in Novel approaches and satrategies for biologics, vaccines and cancer therapies. eds: M singh and M salnikova. elsevier.

Di cerbo, V, Mohn, F, Ryan, DP, Montellier, e, Kacem, s, tropberger, P, Kallis, e, Holzner, M, Hoerner, L, Feldmann, A, Richter, FM, Bannister, AJ, Mittler, G, Michaelis, J, Khochbin, s, Feil, R, schuebeler, D, owen-Hughes, t, Daujat, s and schneider, R (2014) Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription. eLife 3:e01632

Djordjevic, MA, Bezos, A, Susanti, S, Marmuse, L, Driguez, H, samain, e, Vauzeilles, B, Beau, JM, Kordbacheh, F, Rolfe, BG, schwörer, R, Daines, AM, Gresshoff, PM and Parish, CR (2014) Lipo-ohitin oligosaccharides, plant symbiosis signalling molecules that modulate mammalian angiogenesis in vitro. PLoS One 9(12):e112635

Dunn, LL, Midwinter, RG, ni, J, Hamid, HA, Parish, CR and stocker, R (2014) new insights into intracellular locations and functions of Heme oxygenase-1. Antioxidants and Redox Signalling 20(11):1723-1742

Dups, JN, Pepper, M and Cockburn, IA (2014) Antibody and B cell responses to Plasmodium sporozoites. Frontiers in Microbiology 5:625

Ellyard, JI, Jerjen, R, Martin, JL, Lee, AY, Field, MA, Jiang, SH, Cappello, J, Naumann, SK, Andrews, TD, scott, Hs, Casarotto, MG, Goodnow, CC, chaitow, J, Pascual, V, Hertzog, P, Alexander, sI, Cook, MC and Vinuesa, CG (2014) Identification of a pathogenic variant in tReX1 in early-onset cerebral systemic lupus erythematosus by whole-exome sequencing. Arthritis & Rheumatism 66(12):3382-3386

Enders, A, Short, A, Miosge, LA, Bergmann, H, Sontani, Y, Bertram, EM, Whittle, B, Balakishnan, B, Yoshida, K, Sjollema, G, Field, MA, Andrews, TD, Hagiwara, H and Goodnow CC, (2014) Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America 111(12):4513-4518

engelthaler, DM, Hicks, nD, Gillece, JD, Roe, cc, schupp, JM, Driebe, eM, Gilgado, F, carriconde, F, trilles, L, Firacative, c, ngamskulrungroj, P, castaneda, e, Lazera, MD, Melhem, Msc, Perez-Bercoff, A, Huttley, G, sorrell, tc, Voelz, K, May, Rc, Fisher, Mc, thompson, GR, Lockhart, sR, Keim, P and Meyer, W (2014) Cryptococcus gattii in north American Pacific northwest: Whole-population genome analysis provides insights into species evolution and dispersal. mBIO  5(4): e01464-14

eramudugolla, R, Bielak, AAM, Bunce, D, Easteal, S, cherbuin, n and Anstey, KJ (2014) Long-term cognitive correlates of traumatic brain injury across adulthood and interactions with APoe genotype,

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64 the John curtin school of Medical Research

sex, and age cohorts. Journal of the International Neuropsychological Society 20(4):444-454

Fiorani, L, Maccarone, R, Fernando, N, colecchi, L, Bisti, s and Valter, K (2014) slow release drug delivery through elvax for the long-term treatment of the retina using APB. Journal of Visualized Experiments 91:10.3791/51563

Frese, M, Lee, E, Larena, M, Lim, PS, Rao, s, Matthaei, KI, Khromykh, A, Ramshaw, I, Lobigs, M (2014) Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties. Journal of Virology 88(4):2056-2070

Furuya, Y, Wijesundara, DK, neeman, t and Metzger, DW (2014) Use and misuse of statistical significance in survival analyses. mBIO 5(2):e00904

Gang, BP, Dilda, PJ, Hogg, PJ and Blackburn, AC (2014) targeting of two aspects of metabolism in breast cancer treatment. Cancer Biology and Therapy 15(11):1533-1541

Giacci, MK, Wheeler, L, Lovett, s, Dishington, e, Majda, B, Bartlett, cA, thornton, e, Harford-Wright, e, Leonard, A, Vink, R, Harvey, AR, Provis, J, Dunlop, sA, Hart, ns, Hodgetts, s, Natoli, R, Van Den Heuvel, c and Fitzgerald, M (2014) Differential effects of 670 and 830nm red near infrared irradiation therapy: A comparative study of optic nerve injury, retinal degeneration, traumatic brain and spinal cord injury. PLoS 9(8):e104565

Giraudeau, P, Tea, I, Remaud, Gs, Akoka, s (2014) Reference and normalization methods: essential tools for the intercomparison of nMR spectra. Journal of Pharmaceutical and Biomedical Analysis 93:3-16

Graessler, J, Bornstein, tD, Goel, D, Bhalla, VP, Lohmann, t, Wolf, t, Koch, M, Qin, Y, Licinio, J, Wong, ML, chavakis, t, Xu, A, shevchenko, A, schuhmann, K, schwarz, Pe, schulte, KM, Patel A and Bornstein sR (2014) Lipidomic profiling before and after Roux-en-Y gastric bypass in obese patients with diabetes. The Pharmacogenomics Journal 14(3):201-207

Gready, J (2014) Best of the old and the new: a way forward for the food security dilemma? In: A Love of Ideas. ed: H sykes. Future Leaders, sydney. pp69-82

Gready, J (2014) Best-fit options of crop staples for food security: productivity, nutrition and sustainability. In: Handbook on food: demand, supply, sustainability and security eds: R Jha, R Gaiha and AB Deolalikar. edward elgar Publishing,

cheltenham, UK and northampton, MA, UsA. pp381-421

Gyngell, c and Easteal, S (2014) How Moral is (Moral) enhancement? cognitive Diversity and Moral enhancement. Cambridge Quarterly of Healthcare Ethics 24(1):66-74

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Hussein, sM, Puri, Mc, tonge, PD, Benevento, M, corso, AJ, Clancy, JL, Mosbergen, R, Li M, Lee, Ds, cloonan, n, Wood, DL, Munoz, J, Middleton, R, Korn, o, Patel, HR, White, cA, shin, JY, Gauthier, Me, Lê cao, KA, Kim, JI, Mar, Jc, shakiba, n, Ritchie, W, Rasko, Je, Grimmond, sM, Zandstra, PW, Wells, cA, Preiss, T, seo, Js, Heck, AJ, Rogers, IM and nagy, A (2014) Genome-wide characterization of the routes to pluripotency. Nature 516(7530):198-206

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Irons, J, McKone, e, Dumbleton, R, Barnes, n, He, XM, Provis, J, Ivanovici, c and Kwa, A (2014) A new theoretical approach to improving face recognition in disorders of central vision: Face caricaturing. Journal of Vision 14(2):10.1167

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Jackson, RJ, Worley, M, Trivedi, S and Ranasinghe C (2014) novel HIV IL-4R antagonist vaccine strategy can induce both high avidity cD8 t and B cell immunity with greater protective efficacy. Vaccine 32(43):5703–5714

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Joseph, S, Kwan, AH, stokes, PH, Mackay, JP, cubeddu, L and Matthews, JM (2014) the structure of an LIM-only protein 4 (LMo4) and Deformed epidermal autoregulatory factor-1 (DeAF1) complex reveals a common mode of binding to LMo4. PLoS One 9(10):e109108

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Kelemen, RK, He, GF, Woo, HL, Lane, t, Rempe c, Wang, J, Cockburn, IA, Amino, R, Ganusov, VV and Berry MW (2014) classification of t cell movement tracks allows for prediction of cell function. International Journal of Computational Biology and Drug Design 7(2-3):113-29

Kiley, M, Luca, J and Cowan, A (2014) coursework in Australian PhD programmes: Why is this a boundary and how is it being pushed? In: Pushing boundaries in postgraduate supervision eds: e Bitzer, R Albertyn, L Frick, B Grant and F Kelly. sun Press, south Africa. pp123-132

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Kuo, IYT, Howitt, L, sandow, sL, McFarlane, A, Hansen, PB and Hill, CE (2014) Role of t-type channels in vasomotor function: team player or chameleon? Pflugers Archiv-European Journal of Physiology 466(4):767-779

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Liang, B, soka, M, christensen, AH, olesen, Ms, Larsen, AP, Knop, FK, Wang, F, nielsen, JB, Andersen, Mn, Humphreys, D, Mann, sA, Huttner, IG, Vandenberg, JI, svendsen, JH, Haunso, s, Preiss, T, seebohm, G, olesen, sP, schmitt, n and Fatkin, D (2014) Genetic variation in the two-pore domain potassium channel, tAsK-1, may contribute to an atrial substrate for arrhythmogenesis. Journal of Molecular and Cellular Cardiology 67:69-76

Lidbury, BA and Mahalingam, s (2014) Dengue virus and host antibody: a dangerous balancing act. Lancet Infectious Diseases 14(9):783-784

Londono, Ac, castellanos, FX, Arbelaez, A, Ruiz, A, Aguirre-Acevedo, Dc, Richardson, AM, Easteal, S, Lidbury, BA, Arcos-Burgos, M and Lopera, F (2014) An H-1-MRs framework predicts the onset of Alzheimer’s disease symptoms in Psen1 mutation carriers. Alzheimers & Dementia 10(5):552-561

McDonald, Js, Adibi, M, clifford, cWG and Arabzadeh, E (2014) sampling time and performance in rat whisker sensory system. PLoS One 9(12):10.1371

Maddess, T (2014) Modeling the relative influence of fixation and sampling errors on retest variability in perimetry. Graefe’s Archive for Clinical and Experimental Ophthalmology 252(10):1611-1619

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Parish, CR (2014) Immunology and cell Biology turns 90. Immunology and Cell Biology 92(1):1-5

Parish, IA, Marshall, HD, staron, MM, Lang, PA, Brüstle, A, chen, JH, cui, W, tsui, Yc, Perry, c, Laidlaw, BJ, ohashi, Ps, Weaver, ct and Kaech sM (2014) chronic viral infection promotes sustained th1-derived immunoregulatory IL-10 via BLIMP-1. The Journal of Clinical Investigation 124(8):3455-68

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Rutar, M, Valter, K, Natoli, R and Provis, JM (2014) synthesis and propagation of complement c3 by microglia/monocytes in the aging retina. PLoS One 9(4):e93343

Sabeti, F, Maddess, T, Essex, RW, Saikal, A, James, AC and Carle, CF (2014) Multifocal pupillography in early age-related Macular Degeneration. Optometry and Vision Science 91(8):904-915

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Sedger, LM, seddiki, n and Ranasinghe, C (2014) cytokines & cytokine receptors as immunotherapeutics: Humble beginnings and exciting future. Cytokine & Growth Factor Reviews 25(4):351-353

sheng, Kc, Herrero, LJ, taylor, A, Hapel, AJ and Mahalingam, s (2014) IL-3 and csF-1 Interact to promote generation of cD11c+ IL-10-producing macrophages. PLoS One 9(4):e95208

Siggs, OM, Yates, AL, schlenner, s, Liston, A, Lesage, S and Goodnow, CC (2014) A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling cD69 induction. Immunology 141(4):587-595

Soboleva, TA, Nekrasov, M, Ryan, DP and Tremethick, DJ (2014) Histone variants at the transcription start-site. Trends in Genetics 30(5):199-209

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staron, MM, Gray, sM, Marshall, HD, Parish, IA, chen, JH, Perry, cJ, cui, G, Li, Mo and Kaech sM (2014) the transcription factor Foxo1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral cD8(+) t cells during chronic infection. Immunity 41(5):802-14

Stronks, HC and Dagnelie, G (2014) the functional performance of the Argus II retinal prosthesis. Expert Review of Medical Devices 11(1):23-30

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Zabeau, L, Jensen, cJ, seeuws, s, Venken, K, Verhee, A, catteeuw, D, van Loo, G, chen, H, Walder, K, Hollis, J, Foote, S, Morris, MJ, Van der Heyden, J, Peelman, F, oldfield, BJ, Rubio, JP, ele-waut, D and tavernier, J (2014) Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor inter-action level. Cellular and Molecular Life Sciences 72(3):629-44

Zafar, A, Wu, F, Hardy, K, Li, J, tu, WJ, Mccuaig, R, Harris, J, Khanna, KK, Attema, J, Gregory, PA, Goodall, GJ, Harrington, K, Dahlstrom, Je, Boulding, t, Madden, R, tan, A, Milburn, PJ and Rao s (2014) chromatinized protein kinase c-Θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Molecular and Cellular Biology 34(16):2961-2980

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68 the John curtin school of Medical Research

PResentAtIons

Associate Professor Ehsan ArabzadehCoding efficiency and sensory adaptation

Keynote Lecture, 4th computational neuroscience Workshop, IAsBs, Zanjan, Iran

Models in sensory decision-making

ARc centre of excellence for Integrative Brain Function, satellite session on Modeling, University of Queensland, Brisbane, QLD

Associate Professor Mauricio Arcos - BurgosPresentation to Yangon University Short Curse on Social and Demographic Research Methods Training

Department of Anthropology school of culture, History and Language, AnU college of Asia Pacific the Australian national University, canberra, Act

Genomics and Predictive Medicine: a Contribution without Pharmaceutical Cost

Invited Lecture, University of Rosario, Bogota, colombia

Professor John BekkersSynapses and circuits for the cortical processing of odours

Plenary speaker, 32nd Australasian Winter conference on Brain Research, Queenstown, nZ

Dr Edward BertramLinking causal relationships between genes and phenotypes of the immune system through large scale ENU mutagenesis of the mammalian genome

International symposium of the Korean Association for Laboratory Animal science, Yeosu, Korea

The Missense Mutation Library: a resource of hundreds of thousands of new mouse models to study human disease

towards Precision Medicine: Phenotyping human diseases in mice, the 16th Frank and Bobbie Fenner conference, the John curtin school of Medical Research, AnU, canberra, Act

The Missense Mutation Library: a resource of hundreds of thousands of new mouse models to study human disease

International Mouse Phenotyping consortium Annual Meeting, La Pedrera, Barcelona, spain

The Centre for Personalised Immunology

Australian Research Management society conference, national convention centre, canberra, Act

Dr Anneke BlackburnTargeting Cancer Cell Metabolism with Dichloroacetate

Public Lecture in conjunction with the John James Foundation tony Ayers Award for excellence in translational Medicine, JcsMR Public Lecture series, the John curtin school of Medical Research, AnU, canberra, Act

Polymorphisms in Cyp2r1 and disruption of the vitamin D pathway may contribute to breast cancer susceptibility in mice

Annual Meeting of the Genetics society of AustralAsia, sydney, nsW

Targeting cancer metabolism and drug resistance with dichloroacetate

Invited seminar: Pioneer Valley Life sciences Institute, University of Massachusetts, springfield, MA, UsA

Dichloroacetate: More than just a substrate for Glutathione Transferase Zeta

the 15th Frank and Bobbie Fenner conference: Professor Philip Board’s contributions to Molecular Medicine, the John curtin school of Medical Research, AnU, canberra, Act

Dr Anne BruestleMALT1 is an intrinsic regulator of T regulatory cells

DGfI t cell Responses Meeting, Marburg, Germany

My journey with T helper cell subsets in good times and in bad

10th spring school on Immunology, ettal, Germany

Inflammatory T cell responses - Picking the brain on Th17

JcsMR school seminar series, the John curtin school of Medical Research, the Australian national University, canberra, Act

Dr Corinne CarleMultifocal stimuli presented in spatially-clustered volleys increase SNRs in pupil perimetry

21st International Visual Field and Imaging symposium, new York, nY, UsA

Objective perimetry using the pupil response: assessment of visual function without pushing anyone’s buttons

2nd Annual eMBL Australia PhD course, canberra, Act

How normal pupils behave: towards a predictive model of multifocal pupil responses for the identification of visual dysfunction

eccles Institute of neuroscience seminar series, the John curtin school of Medical Research, canberra, Act

Associate Professor Ian Cockburn Imaging the CD8+ T cell responses to Plasmodium in the lymph nodes and liver

Invited speaker, Australian society for Parasitology Annual Meeting, canberra, Act

Imaging the CD8+ T cell responses to Plasmodium in the lymph nodes and liver

Invited speaker, University of Melbourne, Melbourne, VIc

Imaging the CD8+ T cell responses to Plasmodium in the lymph nodes and liver

Invited speaker, Brisbane Immunology Group Annual Meeting, Gold coast, QLD

How do CD8+ T cells find and eliminate parasites in the liver

Invited speaker, University of Washington, seattle, WA, UsA

How do CD8+ T cells find and eliminate parasites in the liver

Invited speaker, Queensland Institute for Medical Research, Brisbane, QLD

Dr Vincent DariaLight-Neuron Interactions: Key to understanding the brain

Invited speaker: Japanese society of Applied Physics – optical society of America Joint symposium, Hokkaido University, Hokkaido, Japan

school of Physics and Astronomy, University of Glasgow, Glasgow, scotland

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Annual Review 2014 69

Institute of neuroscience and Psychology, University of Glasgow, Glasgow, scotland

Photonics Department, technical University of Denmark, Risoe, Denmark

Department of Applied Physics, osaka University, osaka, Japan

center for Information and neural networks, osaka University, osaka, Japan

Dr Michael DobbieBalancing the Responsibilities to Animal Welfare and Human Health

RsPcA Innovative Methods and Alternatives to Animals symposium, the Australian national University, canberra, Act

The Mouse and the Australian Phenomics Network – Serving Experimental Genetics Australia-wide

2nd Annual eMBL Australia PhD course, canberra, Act

Dr Guowen DuanmicroRNA and mRNA 3’UTR processing variations in cardiac biology

Joint Australia and Japan RnA Meeting, sydney, nsW

Characterization of the interactions between RNA and ‘moonlighting’ metabolic enzymes in rodent cardiomyocytes and their change in response to stress

Australian society for Medical Research Act new Investigators Forum, canberra, Act

Mutations in Roquin prolong microRNA longevity in Lupus mice

Australian society for Medical Research Act new Investigators Forum, canberra, Act

Roquin binds microRNA-146a and Argonaute2 and regulates microRNA homeostasis in T cells

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

PAR-CLIP profiling of Roquin-bound RNAs in human T cells

3rd nIF Winter school on Advanced Immunology, Awaji Island, Japan

Dr Julia EllyardCytokine dysregulation in autoimmune disease pathogenesis

cytokines Down Under in 2014: From the Bench to Beyond, Melbourne, VIc

Understanding Genetic Causes of SLE in the age of Personalised Medicine

towards Precision Medicine: Phenotyping human diseases in mice, the 16th Frank and Bobbie Fenner conference, the John curtin school of Medical Research, AnU, canberra, Act

Cytokine dysregulation in autoimmune disease

cytokines Down Under: From Bench to Beyond, Melbourne, VIc

Whole exome sequencing in early-onset cerebral SLE identifies a pathogenic variant in TREX1

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

Whole exome sequencing in early-onset cerebral SLE identifies a pathogenic variant in TREX1

6th Australasian society for Immunology nsW and Act Annual Branch Retreat, Bowral, nsW

Whole exome sequencing in early-onset cerebral SLE identifies a pathogenic variant in TREX1

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

What does Personalised Medicine in Immunology mean?

sanofi Immunology Master class, MsGM executive conference centres, Macquarie Park, nsW

Dr Anselm EndersExpression of IgD on mature B cells is dependent on zinc-finger protein ZFP318

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

Investigating B cell immunodeficiency using ENU mutagenesis

Invited seminar: the Walter and eliza Hall Institute of Medical Research, Melbourne, VIc

Primary immunodeficiencies: From mice to men

Invited speaker: International symposium

of the Korean Association for Laboratory Animal science, Yeosu, Korea

Using mice to understand the human immune system

5th Bootes course on translational Medicine, the John curtin school of Medical Research, the Australian national University, canberra, Act

Primary immunodeficiencies: From mice to men

Ludwig-Maximilians University, Munich, Germany

Professor Simon FooteInvited Speaker

tokyo University, tokyo, Japan

Invited Speaker

towards Precision Medicine: Phenotyping human diseases in mice, the 16th Frank and Bobbie Fenner conference, the John curtin school of Medical Research, AnU, canberra, Act

Invited Observer (representing Australia as Observer to Council)

eMBL Meeting, Heidelberg, Germany

Professor CC Goodnow Germinal Center Selection for Lower Autoantigen Affinity and for V-Regions Blocked by N-Glycans: Redemption of Autoantibodies Carried by Anergic B Cells in the Pre-Immune Repertoire

Keystone symposium: Biology of B cell Responses, Keystone, co, UsA

Self-nonself discrimination by antibodies: clonal selection for somatic mutations in V-regions and in oncogenic signalling molecules

UcsF Department of Microbiology & Immunology, san Francisco, cA, UsA

Self-nonself discrimination by antibodies: clonal selection for somatic mutations in V-regions and in oncogenic signalling molecules

Genetech Inc, san Francisco, cA, UsA

Self-nonself discrimination by antibodies: clonal selection for somatic mutations in V-regions and in oncogenic signalling molecules

2014 cold spring Harbor Meeting, Gene Expression and Signaling in the Immune System, cold spring Harbor, nY, UsA

Self-nonself discrimination by antibodies: clonal selection for somatic mutations in

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70 the John curtin school of Medical Research

V-regions and in oncogenic signalling molecules

stanford University, san Francisco, cA, UsA

Recurring mutations in human lymphoid cancer switch inhibitory signals from normal self into growth stimulatory signals

7th Garvan signalling symposium, Garvan Institute of Medical Research, sydney, nsW

Mendel’s Long tail: the impact of mis-sense mutations on immunity

towards Precision Medicine: Phenotyping human diseases in mice, the 16th Frank and Bobbie Fenner conference, the John curtin school of Medical Research, AnU, canberra, Act

Professor Jill GreadyResearch focused on Global Sustainable Food Provision

Invited speaker: the Future of the University and the University of the Future: A Global Perspective, Universidad técnica de Ambato, ecuador

Dr Rebecca HaddockState of the Heart

Australian Vascular Biology society / High Blood Pressure society of Australia, Adelaide, sA

Obesity-related hypertension: Interaction of the immune and sysmpathetic nervous systems

experimental Biology (American Physiological society), san Diego, cA, UsA

Perivascular inflammation drives sympathetic hyperinnervation and hypertension in obesity

combined Research Forum, canberra Hospital, canberra, Act

Cause of Hypertension in the Obese

5th Bootes course on translational Medicine, the John curtin school of Medical Research, the Australian national University, canberra, Act

Obesity and the Nervous system

2nd Annual eMBL Australia PhD course, canberra, Act

Associate Professor Guna KarupiahInduction of long-lived antiviral antibody responses

QIMR Berghofer Medical Research Institute, Brisbane, QLD

Professor Trevor LambEvolution of vertebrate photoreception and retinoid cycle: Clues from agnathans

eeMB seminar series, University of california santa Barbara, santa Barbara, cA, UsA

Evolution of vertebrate photoreception and retinoid cycle: Clues from agnathans.

Invited speaker: International society for eye Research, XXI Biennial Meeting, san Francisco, cA, UsA

Evolution of vertebrate photoreception: Clues from hagfish and lamprey eye transcriptomes

Invited seminar: neuroecology Group, University of Western Australia, Perth, WA

Evolution of vertebrate photoreception: Clues from hagfish and lamprey eye transcriptomes

Invited conference presentation: Genes, epigenetics and evolution in eye Development and Disease, oropesa, spain

Evolution of vertebrate photoreception and retinoid cycle: Clues from the eye transcriptome of basal vertebrates

Invited seminar, Departament de Genètica, Universitat de Barcelona, Barcelona, spain

Extraction of photoreceptor and bipolar cell responses from the ERGs of normal human subjects

Invited seminar, Institute of ophthalmology, University college, London, UK

Evolution of vertebrate photoreception and retinoid cycle: Clues from the eye transcriptome of basal vertebrates

Invited seminar, Kenneth craik club, University of cambridge, cambridge, UK

Dr Yalin LiaoRBP atlas: an exploration of interactions between mRNA and proteins and their impact on cardiomyocyte biology

Joint Japanese and Australia RnA meeting, sydney, nsW

RBP atlas: an exploration of interactions between mRNA and proteins and their impact on cardiomyocyte biology

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

RBP atlas: an exploration of interactions between mRNA and proteins and their impact on cardiomyocyte biology

comBio 2014, canberra, Act

Associate Professor Brett LidburyAbsolute replacement concepts for biomedical research and the scientific challenge of human diversity

RsPcA Innovative Methods and Alternatives to Animals symposium, the Australian national University, canberra, Act

Fluorescent Target Array reduces mouse numbers while assessing multiple post-vaccination T-cell responses

9th World congress on Alternatives and Animal Use in the Life sciences, Prague, czech Republic

Proton magnetic resonance spectroscopy and recursive partitioning analysis of brain metabolism data from an Alzheimer’s disease cohort offers a replacement alternative for animal studies on disease prediction

9th World congress on Alternatives and Animal Use in the Life sciences, Prague, czech Republic

Professor Ted MaddessStructure and Function in Multifocal Pupillographic Objective Perimetry (mfPOP)

Imaging and Perimetry society, new York, nY, UsA

Structure and Function in Multifocal Pupillographic Objective Perimetry (mfPOP)

World ophthalmology congress, tokyo, Japan

Dr Claudio MastronardiTemporal gene expression in the hippocampus and peripheral organs in mice resilient to systemic inflammatory response

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Annual Review 2014 71

9th congress of the International society for neuroImmunoModulation, Liege, Belgium

Dr Maxim NekrasovDifferent Strategies of chromatin remodelling at the trasncription start site

comBio 2014, canberra, Act

Professor Christopher R ParishPathways to the development of novel drugs against cancer, diabetes and sepsis

2nd Annual eMBL Australia PhD course, canberra, Act

Type 1 diabetes and sepsis at JCSMR: Heparan sulphate mimetics as therapeutics

Paediatric Grand Rounds, the canberra Hospital, canberra, Act

The pathway from lab finding to clinical trial

5th Bootes course on translational Medicine, the John curtin school of Medical Research, the Australian national University, canberra, Act

Dr Hardip PatelRNAnexus: A framework for RNA data mining and visualization

Annual Meeting of the Genetics society of AustralAsia, sydney, nsW

Dr Gilberto Paz-FilhoLeptin therapy: facts and expectations

the Australian Institute of sport, canberra, Act

Overview of Translational Medicine

5th Bootes course on translational Medicine, the John curtin school of Medical Research, the Australian national University, canberra, Act

Endocrine Research in Brazil and Turkey

5th Bootes course on translational Medicine, the John curtin school of Medical Research, the Australian national University, canberra, Act

Pathways for a career overseas

31st Brazilian congress of endocrinology and Metabolism, curitiba, Brazil

ENDO Tribute: Twenty years of the revolutionary leptin

Plenary lecture: 31st Brazilian congress of endocrinology and Metabolism, curitiba, Brazil

Twenty Years of Leptin

são Paulo state University (UnesP) school of Medicine, são Paulo, Brazil

Whole-exome sequencing for the diagnosis of monogenic obesity

são Paulo state University (UnesP) school of Medicine, são Paulo, Brazil

Translational Medicine

translational and clinical sciences Workshop, 2nd Annual eMBL Australia PhD course, canberra, Act

Professor Thomas PreissMechanisms and patterns of eukaryotic post-transcriptional gene control

speaker & session chair: csH Asia RnA Biology conference, suzhou china

Mechanisms and patterns of eukaryotic post-transcriptional gene control

IUPAB International Biophysics congress, Brisbane QLD

Role of the 5-methylcytosine as a widespread modification of RNA

FAseB sRc: Machines on Genes: nucleic Acid enzymes, snowmass, co, UsA

Importance of RNA-mediated gene regulation

co-convenor, session chair & speaker, 2nd Annual eMBL Australia PhD course, canberra, Act

RNA-mediated gene regulation in cardiac biology

5th Bootes course on translational Medicine, the John curtin school of Medical Research, the Australian national University, canberra, Act

Mechanisms and patterns of eukaryotic post-transcriptional gene control

Julian Wells Medal Lecture, Australian Genome conference, Lorne, VIc

Dr Charani RanasingheHIV vaccines eliciting broad protective responses

AIDs2014 AcH2 satellite meeting, International Master class and workshop on HIV prevention, control and cure, Doherty Institute, Melbourne, VIc

A novel triple action mucosal/systemic HIV-1 vaccine strategy

AIDs2014 symposia session Determinants of transmission: Interactions with Biomedical Prevention strategies, Melbourne, VIc

Dr Stuart ReadMissense Mutation Library; Hundreds of thousands of mouse models for understanding human disease

International Mouse Phenotyping consortium Annual Meeting, Barcelona, spain

Associate Professor Charmaine SimeonovicDepletion of intracellular heparan sulfate in islet beta cells: a critical link between Type 1 diabetes and Type 2 diabetes

Department of Internal Medicine III, Medical Faculty carl Gustav carus, Dresden University of technology, Dresden, Germany

Depletion of intracellular heparan sulfate in islet beta cells: a critical link between Type 1 diabetes and Type 2 diabetes

school of Medicine, University of tampere, tampere, Finland

Depletion of intracellular heparan sulfate in islet beta cells: a critical link between Type 1 diabetes and Type 2 diabetes

Department of Biological and environmental science, University of Jyväskylä, Jyväskylä, Finland

Depletion of intracellular heparan sulfate in islet beta cells: a critical link between Type 1 diabetes and Type 2 diabetes

Institute of Biomedical and clinical science, University of exeter Medical school, exeter, UK

Depletion of beta cell heparan sulfate (HS) in T2D-prone db/db mice results from diminished heparan sulfate proteoglycan (HSPG) core protein levels

Annual scientific Meeting of the Australian Diabetes society and the Australian Diabetes educator Association, Melbourne, VIc

Depletion of intracellular heparan sulfate in islet beta cells: a critical link between type 1 diabetes and type 2 diabetes

Department of Immunology seminar series, the John curtin school of Medical Research, AnU, canberra, Act

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72 the John curtin school of Medical Research

Associate Professor Christian StrickerA trp into ion channels involved in thymocyte selection

eccles Institute of neuroscience seminar series, the John curtin school of Medical Research, the Australian national University, canberra, Act

Single-cell techniques in Neuroscience unravelling brain function

2nd Annual eMBL Australia PhD course, canberra, Act

Professor Greg Stuart Brain mechanics: The nuts and bolts of how your brain works

4th Annual John curtin Lecture in Medical Research, canberra, Act

Dendritic integration

okinawa computational neuroscience course, okinawa, Japan

Axons & excitability

okinawa computational neuroscience course, okinawa, Japan

Binocular integration

Allen Brain Institute, seattle, WA, UsA

Single neuron computation

Monash neuroscience seminar series, Monash University, Melbourne, VIc

Dr Rebecca SweetHuman T follicular regulatory cells are the source of IL-10 to drive plasma cell differentiation from germinal center B cells

6th Australasian society for Immunology nsW and Act Annual Branch Retreat, Bowral, nsW

Human T follicular regulatory cells signal directly to germinal centre B cells using IL-10

Australian society for Medical Research Act new Investigators Forum, canberra, Act

Human T follicular regulatory cells signal directly to germinal centre B cells using IL-10

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

Dr Malinda TantirigamaLaminar representation of odour in the mouse piriform cortex in vivo

32nd Australasian Winter conference on Brain Research, Queenstown, nZ

Laminar representation of odour in the mouse piriform cortex in vivo

UWs sensory neuroscience symposium, sydney, nsW

Professor David TremethickUncovering new functions of chromatin: the role of histone variants in pre mRNA splicing

eMBo workshop on histone variants, strasbourg, France

Inheritance of H2A.Z from cell generation to the next

Asian transcription meeting, Melbourne, VIc

A new role for histone variants in splicing regulation

Gordon conference: chromatin structure and Function, Boston, MA, UsA

Uncovering new functions of chromatin: functional specialisation by histone variants

school of Molecular and Biomedical sciences, the University of Adelaide, Adelaide, sA

Dr Krisztina ValterPhotobiomodulation with 670nm in models of retinal degeneration

Invited keynote presentation: Australian Medical Laser Association, sydney, nsW

670nm – a stop sign for retinal degeneration?

Invited keynote presentation: World Association for Laser therapy/north American Association for Photobiomodulation therapy Joint conference, Washington, Dc, UsA

Discussions on the mechanism of 670nm light treatment on the retina

Invited symposium presentation: World Association for Laser therapy - north American Association for Photobiomodulation therapy Joint conference, Washington, Dc, UsA

Professor Carola G Vinuesa T cell subsets that control B cell responses: More than meet the eye

cell symposium: the Multifaceted Roles of type 2 Immunity, Bruges, Belgium

MicroRNA-mediated repression of T follicular helper cells and germinal centers

3rd International conference on Immune tolerance, Amsterdam, netherlands

Tfh Cell Regulation to Prevent Systemic Autoimmunity

FocIs 2014, Annual Meeting of the Federation of clinical Immunology societies, chicago, IL, UsA

miRNA-mediated control of Tfh cells and germinal center responses

Immunology 2014 symposium: Genetic control of Immunity, Pittsburgh, PA, UsA

Regulation of Tfh cell numbers and function

27th Annual Meeting of the canadian society of Immunology: Germinal center Reaction in Health and Disease, Quebec, canada

Novel Mechanisms Controlling Mouse and Human Follicular T Cell Homeostasis

Keystone symposium: Biology of B cell Responses, Keystone, co, UsA

Multiple mechanisms operate to regulate T cell help for B cells

3rd nIF Winter school on Advanced Immunology, Awaji Island, Japan

Why do we still know so little about autoimmune disease aetiology?

the Jonathan sprent oration, Brisbane Immunology Group 15th Annual Retreat, QIMR-Berghofer Medical Research Institute, Gold coast, QLD

Dr Stephen WinsladeTranslational Commercialisation of Research

Asian Mouse Phenotyping consortium student Workshop, canberra, Act

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S Achuthan and AC BlackburnTargeting glucose metabolism - a strategy for overcoming drug resistance in breast cancer

comBio 2014, canberra, Act

Targeting glucose metabolism — a strategy for overcoming drug resistance in breast cancer

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

FA Agahari and C StrickerSerotonergic modulation of neurotransmitter release in layer II/III pyramidal neurons in rat somatosensory cortex

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

Opposite modulation of spontaneous and evoked transmitter release in layer II/III pyramidal cell in rat somatosensory cortex through 5-HT2 Gq-protein-coupled receptor (GqPCR)

Meeting of the society of neuroscience, Washington, UsA

EN Ali, T Maddess, CF Carle and CJ LueckEffects of stimulating melanopsin-containing retinal ganglion cells in migraine patients using multifocal objective pupillometry

eFns-ens Joint congress of european neurology, Istanbu turkey

EN Ali, T Maddess, K Martin, A Borbell and CJ Lueck Testing the safety of multifocal pupillographic objective perimetry (mfPOP) in patients with photosensitive epilepsy

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

Z Al RumaihThe role of viral TNFR (crmD) in the host response to poxvirus infection

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

H BergmannRemoval of p8-CD74 peptides by intramembrane endopeptidase SPPL2A is crucial for B cell survival

Departmental of Immunology seminar, Whitehead Institute, Boston, MA, UsA

Complete degradation of CD74-invariant chain by the endopeptidase SPPL2A is necessary for B cell responsiveness and survival

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

Removal of p8-CD74 peptides by intramembrane endopeptidase SPPL2A is crucial for B cell survival

Keystone symposia: Biology of B cell Responses, Keystone, co, UsA

T BockImpact of sK channels on cortical excitability in vivo

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

RH Chia, R Mallikarjunan, CF Carle et al. Objective perimetry in diagnosing early retinopathy in type II diabetes

Australian Diabetes society & Diabetes education Association

S Dhounchak, S Popp, H Vohra, T Biden, R Laybutt, C Parish and C SimeonovicDiminished heparan sulfate proteoglycan (HSPG) core protein levels correlate with the depletion of heparan sulfate (HS) in the islets of T2D-prone db/db mice

Australian Islet study Group Meeting (AIsG), Brisbane, QLD

Beta cell heparan sulfate and heparan sulfate proteoglycan loss in Type 2 Diabetes

Australian society for Medical Research (AsMR) Act new Investigator Forum, canberra, Act

P EldiInduction of long-term humoral immunity using replicating and non-replicating poxviral models

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

N FernandoThe therapeutic potential of the complement inhibitor VCP in a model of retinal degeneration

16th european Molecular Biology Laboratory (eMBL) International PhD symposium, Heidelberg, Germany

The use of the complement inhibitor VCP in the retina

1st european Molecular Biology Laboratory (eMBL) Australia PhD symposium, the University of new south Wales, sydney, nsW

R Galgamuwa Arachchige, PG Board, JE Dahlstrom, AC Blackburn, P Tummala, L Tian and A TheodoratosDichloroacetate (DCA) prevents cisplatin-induced acute kidney injury (AKI) by regenerating renal tubular cells while anticancer activity of cisplatin is unaltered.

Australian and new Zealand society of nephrology (AnZsn) Annual scientific Meeting, canberra, Act

R Galgamuwa Arachchige, PG Board, JE Dahlstrom, AC Blackburn, P Tummala and A TheodoratosDichloroacetate (DCA) prevents cisplatin-induced acute kidney injury (AKI) by regenerating renal tubular cells

20th International conference on Advances in critical care nephrology, san Diego, cA, UsA

stUDent PResentAtIons

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74 the John curtin school of Medical Research

S Gharaei, E Arabzadeh and S SolomonDistribution of visual and somatosensory signals in superior colliculus of rat

Kioloa neuroscience colloquium, Kioloa coastal campus

Distribution of visual and somatosensory signals in superior colliculus of rat

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

M-A GoFemtosecond laser dendrotomy

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

Femtosecond laser dendrotomy

Focus on Microscopy, University of sydney, sydney, nsW

Analysing neuronal function using synthesizable photo-switchable nanoparticle agents

Federation of neurosciences society Meeting, Milan, Italy

Femtosecond laser dendrotomy for analyzing morphology dependent neuronal function

Federation of neurosciences society Meeting, Milan, Italy

Analysing morphology-dependent neuronal function using laser dendrotomy

society for neuroscience, Washington Dc, UsA

F Haque, D Nisbet, F Maclean and JR PotasIn vivo macrophage polarisation induced by interleukin 10 (IL10) functionalised electrospun nanofibre scaffolds in the peripheral nervous system

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

D Hu, S Zhu and JR PotasRed light (670 nm) treatment improves functional and cellular outcomes following spinal cord injury

UWs sensory neuroscience symposium, University of Western sydney, sydney, nsW

H Huang Principal neurons respond differently to odour presentation in vivo

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

Principal neurons respond differently to odour presentation in vivo

Kioloa neuroscience colloquium, Kioloa, nsW

Probing neuronal responses with scents

eccles Institute of neuroscience seminar series, the John curtin school of Medical Research, the Australian national University, canberra, Act

Y JeelallCARD11 as the switch between self-antigen induced B cell death or proliferation and autoantibody production (oral and Poster presentation)

Keystone symposia: Biology of B cell responses, Keystone, co, UsA

A novel deep sequencing method for tracking of driver mutations in non-Hodgkin lymphoma

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

Investigating genetic lesions associated with DLBCL cases

Agilent next Generation sequencing seminar, canberra, Act

Novel sequencing methods for tracking driver mutations in non-Hodgkin lymphoma

Department of Immunology seminar series, the John curtin school of Medical Research, AnU, canberra, Act

Characterisation of an ENU-induced gain-of-function Card11 mouse strain as a model for human B cell diseases

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

S JonesAction potential induced suppression of EPSPs by SK channels in dendrites

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

M Khanna, C Ranasinghe, RJ Jackson and CR ParishRole of heparan sulfate in pox virus infections

Keystone symposia, Denver, co, UsA

C Lee and E ArabzadehA novel investigation of sensory prioritization in rats

Kioloa neuroscience colloquium, Kioloa coastal campus

D MenonRedox modification of proteins: Glutathione transferase Omega 1 (GSTO1-1) as a deglutathionylase (Oral and Poster presentation)

Gordon Research conference: Thiol based redox regulation and signalling, Girona, spain

Redox modification of proteins: Glutathione transferase Omega 1 (GSTO1-1) as a deglutathionylase

15th IUBMB-24th FAoBMB conference taipei, taiwan

Glutathione transferase Omega 1 is a novel redox regulator of TLR4-dependent inflammatory signalling in macrophages

15th IUBMB-24th FAoBMB conference: Young scientist Program- (oral and Poster presentation), taichung, taiwan

Glutathione Transferase Omega 1 is a novel redox signalling protein in TLR4 activated macrophages

the 15th Frank and Bobbie Fenner conference: Professor Philip Board’s contributions to Molecular Medicine, the John curtin school of Medical Research, AnU, canberra, Act

Glutathione transferase Omega 1 is a novel redox regulator of TLR4-dependent inflammatory signalling

Australian society for Medical Research new Investigator Forum, canberra, Act

A MicallefA postsynaptic contribution to short-term plasticity in the piriform cortex

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

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Annual Review 2014 75

J RobertsonElectrical stimulation alters patterns of epileptiform activity in the piriform cortex in vivo

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

Using hyper-excitability to probe piriform cortex networks

UWs sensory neuroscience symposium, sydney, Australia

Changing electrical activity in the primary olfactory cortex: what a shock!

Australian society for Medical Research new Investigator Forum, canberra, Act

Changing epileptic activity in the primary olfactory cortex

canberra Health Annual Research Meeting, canberra Hospital, | canberra, Act

A Rodriguez, G Paz–Filho, T Neeman, AG Giles and CA MastronardiMetreleptin improves metabolic and hepatic endpoints in the treatment of non-HAART associated lipodystrophy syndromes: a meta-analysis into the effects of leptin replacement therapy

Annual scientific Meeting of the endocrine society of Australia, Melbourne, VIc

A Meta-Analysis into the Effects of Leptin Replacement Therapy on Metabolic and Hepatic Endpoints of Patients with Lipodystrophy Syndromes Not Associated with the Use of HIV Protease Inhibitors

Annual scientific Meeting of the endocrine society, chicago, IL, UsA

K Samarasinghe, D Liu, P Tummala, L Arnolda, A F Dulhunty and PG BoardThe therapeutic potential of Glutathione transferase Mu-derived peptides to treat heart failure through cardiac ryanodine receptor Ca2+ channel inhibition

Australian society for Medical Research new Investigator Forum, canberra, Act

The therapeutic potential of Glutathione transferase M2-derived peptides to treat heart failure through cardiac ryanodine receptor Ca2+ channel inhibition

43rd european Muscle conference Faculty of natural sciences, University of salzburg, salzburg, Austria

S Senga S, Z-M Song and GDH CroakerDiffuse effects of an endothelin b receptor (ednrb) mutation: more on the non-enteric phenotype of Hirschsprung's disease

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

A Shafik, N Beveridge, T Sibbritt, JE Squires, DT Humphreys, HR Patel, SJ Clark, J Wen, BJ Parker and T PreissEnzymology and molecular function of 5-methylcytosine (m5C) as a modification of human RNA

35th Annual Lorne Genome conference, Lorne, VIc, Australia

A Shafik, T Sibbritt, HR Patel, N Beveridge, SJ Clark, J Wen, BJ Parker and T PreissEnzymology and molecular function of 5-methylcytosine (m5C) as a modification of human RNA

Australian society for Medical Research new Investigator Forum, canberra, Act

Q ShenRepression of LINE-1 Transcription by H2A.Z

the 2nd Max Planck Freiburg epigenetic Meeting, Freiburg, Germany

T Sibbritt, BJ Parker, DT Humphreys, JE Squires. NJ Beveridge, A Shafik, AL Statham, HR Patel, SJ Clark and T Preiss Exploring the role of RNA cytosine methylation in post-transcriptional gene regulation and cancer

comBio 2014, canberra, Act

Investigating the enzymology and molecular function of 5-methylcytosine in RNA

Joint Australia and Japan RnA Meeting, sydney, nsW

The mysteries of RNA methylation: exploring the enzymology and molecular function of 5-methylcytosine in RNA

Gordon Research conference: Post-transcriptional Gene Regulation, newport, RI, UsA

T Sibbritt, BJ Parker, DT Humphreys, HR Patel, AL Statham, SJ Clark and T Preiss Investigating the association of RNA cytosine methylation with post-transcriptional regulation and cancer

Australian society for Medical Research new Investigator Forum, canberra, Act

Investigating the association of RNA cytosine methylation with post-transcriptional regulation and cancer

35th Annual Lorne Genome conference, Lorne, VIc

M SinghOral Presentations

44th Australasian society for Immunology Annual scientific Meeting, Wollongong, nsW

Oral presentation

croucher summer course: Advances in Immunology in Health and Disease, Hong Kong

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76 the John curtin school of Medical Research

R Soetanto, CJ Hynes, HR Patel, D Duan, DT Humphreys, NJ Smith, BJ Parker, SK Archer, TH Beilharz, RM Graham, JL Clancy and T PreissThe dynamics of miRNA-mRNA targeting during cardiac health and disease

1st european Molecular Biology Laboratory (eMBL) Australia PhD symposium, the University of new south Wales, sydney, nsW

mRNA 3’UTR expression during cardiac disease: consequences for miRNA regulation

comBio 2014, canberra, Act

Alternative RnA 3’ end cleavage and polyadenylation during cardiac hypertrophy, Rina soetanto, Joint Australia and Japan RnA Meeting, sydney, nsW

Expression of mRNA 3’UTR isoforms in the heart

Australian society for Medical Research new Investigator Forum, canberra, Act

Shifting targets: microRNA variants and alternative polyadenylation in the heart

35th Annual Lorne Genome conference, Lorne, VIc

Shifting targets: microRNA variants and alternative polyadenylation in the heart

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

Mending a broken heart- a big role for small RNAs

3-Minute thesis competition, the Australian national University, canberra, Act

Mending a broken heart- a big role for small RNAs

the science show, ABc Radio national

I Tea, E Martineau, J Lalande, S Barille, AC Blackburn and G Tcherkez4

Isotopic signature of 13C and 15N natural abundance in breast cancer

comBio 2014, canberra, Act

B Tonson-Older, T Maddess, J Bell and CJ LueckAutomated perimetry in neurological visual field loss

neuro-ophthalmology society of Australia, canberra, Act

Automated perimetry in neurological visual field loss

canberra Health Annual Research Meeting, canberra Hospital,

canberra, Act

LTV Tran and C StrickerSpontaneous Ca2+ transients in nerve terminals of neocortical excitatory neurons

34th Annual Meeting of the Australasian

neuroscience society, Adelaide, sA

Spontaneous Ca2+ transients in nerve terminals of neocortical excitatory neurons

Meeting of the society of neuroscience, Washington, UsA

DK Wijesundara, RJ Jackson, DC Tscharke and C RanasingheHIV-1 vaccine development: evaluating mechanisms by which interleukin (IL)-4 and IL-13 down-regulate the quality of anti-viral HIV-specific CD8+ T cell responses following pox viral vaccination

International AIDs2014 conference, Melbourne, VIc

DK Wijesundara, C Ranasinghe, RJ Jackson, CR Parish and B Quah BAssessing the quality of CD8+ T cell responses in vivo following HIV-1 recombinant pox virus vaccination using a novel fluorescent target array assay

AcH2, Katoomba, nsW

Y-H Wu, JE Dahlstrom, DJ Tremethick and T Soboleva A new function for testis-specific histone variants in cancer

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

D Xie, GDH Croaker, K Stefanoska and Z-M SongDeveloping a model for studying late effects of ednrb malfunction on brain development

canberra Health Annual Research Meeting, canberra Hospital, canberra, Act

M YabasB cell deficiency and anemia caused by mutations in the murine Atp11c gene

erciyes University, Kayseri, turkey

Y Zhang, L Boisseau, P Scott, G Paz–Filho and C NolanIs the Strategy for Care of "Low Risk" Women with Gestational Diabetes Mellitus Really Safe?

74th scientific sessions of the American Diabetes Association, san Francisco, cA, UsA

S Zhu, D Hu and JR PotasBrainstem changes affected by 670 nm photobiomodulation treatment following T10 hemi-contusion spinal cord injury

34th Annual Meeting of the Australasian neuroscience society, Adelaide, sA

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Annual Review 2014 77

Dr Mehdi AdibiParticipant: csIRo scientists and Mathematicians in schools, campbell High school, canberra, Act

Ms Ana AlfaroPresenter and Participant: JcsMR open Day

Presenter and Participant: First canberra ecuadorian Festival, Acton, Act

Ms Nurdiana AnuarVice President: Malaysian Postgraduate student Association-Act chapter

Volunteer: combio 2014, national convention centre, canberra Act

Associate Professor Ehsan ArabzadehAcademic editor: Public Library of Science, PLoS One

Presenter: JcsMR Director’s ‘Health through Discovery’ Public Lecture, Deciphering the language of brain cells

Panellist, public event “Who is in charge, you or your brain?” ARc centre of excellence for Integrative Brain Function, Victorian state Library, Melbourne

spokesperson, Decision theme, ARc centre of excellence for Integrative Brain Function

Academic council Member: Institute for Research in Fundamental sciences, tehran, Iran

Faculty: Australian course in Advanced neuroscience (AcAn), north stradbroke Island, QLD

co-organiser, Kioloa neuroscience colloquium, Kioloa coastal campus

Member: neuroscience Honours committee, JcsMR, AnU, canberra, Act

Member: JcsMR Gender equity committee

Member: Australasian neuroscience society

Member: society for neuroscience (UsA)

Professor Mauricio Arcos-Burgoseditorial Board Member: Molecular Genetics and Genomics Medicine

editorial Reviewer: Nature Genetics; Molecular Psychiatry; Human Genetics, Nephron; Bioinformatics; Translational Psychiatry, Annals of Human Genetics, The ANU Undergraduate Research Journal

Professor John M BekkersDirector: Australian course in Advanced neuroscience (AcAn), Moreton Bay Research station, north stradbroke Island, QLD

Reviewing editor: Frontiers in Neuroscience, BMC Neuroscience

chair: JcsMR scholarships committee

convenor: JcsMR school seminar program

Member: JcsMR executive committee

Member: JcsMR education committee

Member: AnU neuroscience Management committee

Member: JcsMR Grant Feedback committee (neuroscience)

council Member: Australasian neuroscience society

Ex officio Member: AcAn Management committee of the Australasian neuroscience society

Member: Australian Physiological society

Member: society for neuroscience (UsA)

Member: International Brain Research organization (IBRo)

Presenter and Participant: national Youth science Forum, JcsMR, AnU, canberra, Act

Presenter and Host: JcsMR outreach Program, canberra, Act

Dr Andrew Bellconsulting editor: Journal of Hearing Science

Member: Australian Acoustical society

Member: Acoustical society of America

Dr Edward M Bertramsteering committee Member: International Mouse Phenotyping consortium

Member: Finance sub-committee, International Mouse Phenotyping consortium

Australian Member: Board of Directors, Asian Mouse Phenotyping consortium

conference organiser: towards Precision Medicine: Phenotyping human diseases in mice, canberra, Act

Workshop organiser and session chair: Asian Mouse Phenotyping consortium student Workshop, canberra, Act

Meeting organiser: Asian Mouse Mutagenesis and Resource Association- Asian Mouse Phenotyping consortium Annual Meeting, canberra, Act

Dr Anneke Blackburnconvenor: JcsMR cancer Research consumer Representative Panel, the John curtin school of Medical Research and Research school of Biology, the Australian national University, canberra, Act

Presenter: cancer council Act: Biggest Morning tea Launch

Presenter: Breast cancer treatment Group (cancer support network)

Media Interviews: WIn news, ABc news, the canberra times: Non-toxic drug targets cancers sweet spot

Member: AsBMB Australian society for Biochemistry and Molecular Biology

Presenter and Host: JcsMR outreach Program, canberra, Act

Member: American Association for cancer Research

Member: Kathleen cunningham consortium for Research into Familial Breast cancer (kconFaB)

coMMUnItY

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78 the John curtin school of Medical Research

Professor Philip G BoardMember: Act Gene technology Advisory council

Member: International society for the study of Xenobiotics Awards committee

editorial Board Member: The Open Drug Metabolism Journal, Drug Metabolism Reviews, The Sirraj Medical Journal

Mr Bob Buckleyconvenor: Autism Aspergers Advocacy Australia (A4)

chair: speaking out for Autism spectrum Disorder (sofAsD)

Finalist: 2014 Act senior Australian of the Year

Panel Member: nDIA’s Autism early Intervention Review

Presenter: nDIs pre-planning workshops for autism

Ms Holly BurkeMember: Australian and new Zealand Laboratory Animal Association

conference organiser: Australian and new Zealand Laboratory Animal Association Annual conference

Dr Corinne CarleMember: Australiasian neuroscience society

Member: Association for Research in Vision and ophthalmology (ARVo)

convenor: JcsMR eccles Institute of neuroscience seminar series

supervisor: Act Wex (Work experience) Progam

supervisor: AnUMs MchD student Research Program

Associate Professor Marco G CasarottoPresenter and Host: JcsMR outreach Program, canberra, Act

Member and Accounts signatory: Australian society for Biochemistry and Molecular Biology (AsBMB)

Member: Australian society for Medical Research (AsMR)

Member: Australian Biophysics society (ABs)

Member: UsA Biophysical society

nHMRc Grant Review Panel Member: Biochemistry and cell Biology

Dr G ChaudhriMember: Federation of clinical Immunological societies

Member: Australasian society for Immunology

Member: Australian society for Medical Research

Dr Julian ChoyPresenter and Participant: JcsMR open Day

Presenter and Participant: national Youth science Forum, JcsMR, AnU, canberra, Act

Presenter and Participant: Australian Brain Bee challenge, Act Regional Finals, JcsMR, AnU, canberra, Act

Member: Australasian neuroscience society

Member: society for neuroscience (UsA)

Mr Aaron ChuahPresenter: GDUcluster for users. techniques in computational Genomics series, the John curtin school of Medical Research, AnU, canberra, Act

Associate Professor Ian CockburnModule organiser: Australian society for Parasitology, Advanced concepts in Parasitology course, canberra, Act

organizing committee Member: 2014 Australian society for Parasitology Meeting, canberra, Act

organizing committee Member: 2015 Australasian society for Immunology Meeting, canberra, Act

Professor Matthew CookMember: Royal Australasian college of Physicians Research committee

Member: nHMRc Grant review panel - translation Faculty committee

examiner: Royal college of Pathologists of Australasia (Immunopathology)

editorial Board Member: Clinical and Translational Immunology

Dr Lucy Couplandcategory B Member: Animal experimentation ethics committee, AnU

Ms Tiffany CrippsPresenter and Participant: JcsMR outreach Program - AnU BIoL3190 science in the Workplace

Dr Peter CumminsPresenter and Participant: JcsMR open Day

Dr Stephen Daley Act Branch treasurer: Australasian society for Immunology

Dr Vincent DariaMember: Australasian neuroscience society

Member: society for neuroscience (UsA)

Member: Australian optical society

Member: optical society of America

Member: International society for optics and Photonics

Dr Michael DobbieMember: Australia & new Zealand society for cell & Developmental Biology (AnZscDB)

scientific co-convenor: eMBL Australia PhD course, the Australian national University, canberra, Act

Dr Guowen Duaneditorial Board Member: AIMS-Molecular Science, SM Vaccines and Vaccination Journal

Invited editor: special issue - the role of non-coding RnAs in autoimmunity diseases, AIMS-Molecular Science

Reviewer: International Journal of Molecular Sciences

Reviewer: Journal of Vascular Research

Reviewer: International Journal of Biological Sciences

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Annual Review 2014 79

Professor Angela F DulhuntyMember: national committee for Biomedical sciences

Member ARc college

organiser: curtin conference on Muscle, canberra, Act

Member: Australian Physiological society

Member: Biophysical society UsA

editorial Board Member: Calcium Binding Proteins, Ion Channels, The Biochemical Journal

Grant Assessor: ARc AusReader, nHMRc, european, UsA and nZ Granting agencies

Dr Julia EllyardPresenter and Participant: JcsMR open Day

Presenter and Host: national Youth science Forum, JscMR, AnU, canberra, Act

Member: Australasian society for Immunology

Judge: Australian society for Medical Research new Investigator Forum, canberra, Act

Member: Australasian society for Immunology.

organizing committee Member: 45th Annual Meeting of the Australasian society for Immunology, 2015 canberra, Act

Dr Anselm EndersAct councilor: Australasian society of Immunology

organizing committee chair: 45th Annual Meeting of the Australasian society for Immunology, 2015, canberra, Act

co-chair: organizing committee for joint Workshop - Australasian society for Immunology and the German society for Immunology, 2015, canberra, Act

Professor Simon FooteMember: nHMRc Research committee

scientific Advisory Board Member: Ramaciotti Foundation

chair: nHMRc Project Grant Review Panel

Board Member: Royal Hobart Hospital Foundation

Board Member: eMBL Australia council

Grant Reviewer: Australian Research council, the Wellcome trust, the Australian cancer council, the Medical Research council (UK), the Queensland cancer Fund, the nIH, the swiss national Grants system, the national Heart Foundation (Australia), the canadian Health Institutes of Research

Reviewer: Annals of Human Genetics, American Journal of Human Genetics, Genetic Epidemiology, Parasitology Today, International Parasitology, Mammalian Genome, Nature, Nature Medicine, PLoS, PNAS, Research Genetics

Dr Suzanne FowlerMember: Australian and new Zealand Laboratory Animal Association

Member: Veterinary surgeons Board

conference organiser: Australian and new Zealand Laboratory Animal Association Annual conference

Ms Cathy GillespieWorkshop Host: Bio-Medical Imaging students, Research school of engineering, AnU, Molecular and cell biology students, Uc, Biol3190 students, AnU

Ms Dianne GoodingPresident: Australian and new Zealand Laboratory Animal Association

conference organiser: Australian and new Zealand Laboratory Animal Association Annual conference

Professor Christopher C GoodnowMember: Australian Academy of science special elections committee

Member: Wellcome trust Peer Review college, the Wellcome trust, UK

editorial Board Member: Immunity, The Journal of Experimental Medicine, Mammalian Genome, Journal of Autoimmunity, BMC Biology

council Member: eMBL Australia

Vice-President: Australasian society for Immunology

Member: American Association for the Advancement of science

Member: American Association of Immunologists

Professor Jill GreadyPresenter and Participant: JcsMR open Day

editorial Board Member: Bioinformatics and Biology Insights

Member: AnU supercomputing time Allocation committee

Fellow: Royal Australian chemical Institute

Member: Australian society for Biochemistry and Molecular Biology

Member: Australian society for Biophysics

Presenter and Participant: First canberra ecuadorian Festival, Acton, Act

Media Interview: Good Food, the canberra times: Lost crops of the Incas

Dr Rebecca Haddock Member: JcsMR Gender equity committee

Member: nHMRc early career Fellowships Panel

Member: Postgraduate scholarship and Awards committee, JcsMR and AnU Medical school

Vice-President: Australia & new Zealand Microcirculation society

Member: Australasian society of clinical & experimental Pharmacologists and toxicologists

Member: High Blood Pressure Research council of Australia

Member: national Association of Research Fellows

Member: American Heart Association

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80 the John curtin school of Medical Research

Ms Angela HigginsPresenter and Participant: JcsMR open Day

Dr Kesisuke HorikawaMember: Australasian society for Immunology

Ms Helena HuangPresenter and Participant: JcsMR open Day, the John curtin school of Medical Research, AnU, canberra, Act

Presenter and Participant: national Youth science Forum, JcsMR, AnU, canberra, Act

Member: Australasian neuroscience society

Member: society for neuroscience (UsA)

Associate Professor Gavin HuttleyReviewer: Molecular Biology and Evolution; Systematic Biology

editorial Board Membership: Frontiers in Evolutionary and Population Genetics, Biology Direct, PLoS ONE

Reviewer: ARc, nHMRc

Member: Genetics society of Australasia, International society for Molecular Biology and evolution

Mr Cameron JackMember: the Australasian Genomics technologies Association (AGtA)

Presenter and Participant: JcsMR outreach Program - AnU BIoL3190 science in the Workplace AnU

Presenter and Participant: JcsMR open Day

Mr Yogesh Jeelallcoordinator: AsMR Act school Quiz

chair: comBio2014 signalling colloquium

co-organiser: Australasian society for Immunology Act-nsW Branch Meeting

Dr Babu Kannappan Presenter and Participant: JcsMR open Day

Dr Ben KaehlerMember: Genetics society of Australasia

Member: statistics society of Australia

Associate Professor Guna KarupiahVice-President: Federation of Immunological societies of Asia-oceania

Member: American Association of Immunologists

Member: American society for Microbiology

Member: American society Virology

Member: Australasian society for Immunology

Dr Yalin Liao Act Branch committee Member: nutrition society of Australia

Volunteer: scientist and Mathematicians in school

Volunteer: Amaroo school, canberra, Act: Healthy dietary habits - Rainbow eating

Professor Ted MaddessMember: nHMRc Assigners Academy

section editor: clinical and experimental ophthalmology

Member: Board of Administration: national Vision Research Institute, Melbourne, VIc

Member: Board of Directors: Australian council of optometry, Melbourne, VIc

consultant: nIH Grants

Founder: nucoria Pty Ltd

Presenter and Participant: JcsMR clinical suite open Day

Presenter and Participant: JcsMR open Day

Dr Claudio MastronardiMember: International society for neuro-Immuno-Modulation (IsnIM)

Member: society for neuroscience UsA

Member: the endocrine society

Dr Peter MilburnMember: the Association of Biomolecular Resource Facilities (ABRF) UsA

Ms Lorena Nunez VillacisPresenter and Participant: First canberra ecuadorian Festival, Acton, Act

Presenter and Participant: JcsMR open Day

Ms Stephanie PalmerPresenter and Participant: JcsMR outreach Program - AnU BIoL3190 science in the Workplace and AnU BIoL8702 Masters of Biotechnology, Advanced Research techniques

Presenter and Participant: JcsMR open Day

Member: the Australasian Genomics technologies Association (AGtA)

Professor Christopher R ParishFounding Member: World Allergooncology task Force (Vienna-based)

canberra 2014 citizen of the Year

Dr Ian Parish Member: Australasian society for Immunology

organizing committee Member: 45th

Annual Meeting of the Australasian society for Immunology, 2015, canberra, Act

news and commentary editor: Immunology and Cell Biology

Member: scientific Review committee for canberra Health Annual Research Meeting (cHARM) 2014

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Annual Review 2014 81

Dr Hardip PatelMember: the Australasian Genomics technologies Association (AMAtA)

Member: Genetics society of Australasia

Facilitator: Weekly drop-in sessions

Workshop Presentation: Genome sequencing and Annotation: Data Management, at cBA Workshop, canberra, Act

Workshop Presentation: GVL-Galaxy workshop, Genetics society of AustralAsia Annual Meeting, sydney, nsW

Dr Gilberto Paz-Filho editorial Board Member: Brazilian Archives of Endocrinology and Metabolism

Member: Latin American thyroid society

Member: Brazilian society of endocrinology and Metabolism

Member: the endocrine society

committee Member: the endocrine society’s Minority Affairs committee

committee Member: the endocrine society’s Awards Review committee

external Assessor: national Health and Medical Research council Project Grants

Member: editorial Board of translational Gastrointestinal cancer

Member: the Australian national University Human Research ethics committee

Guest editor: special issue of translational Gastrointestinal cancer: Interactions between the endocrine system and the Gastrointestinal tract

Dr Kaiman PengPresenter and Participant: JcsMR outreach Program - AnU BIoL3190 science in the Workplace

Dr Jason PotasAns Representative: science technology Australia

Act council Representative: Australasian neuroscience society

AnU Representative: Australian Medical schools Assessment collaboration (AMsAc)

Finalist: Your science in 60 seconds, science Meets Parliament

PhD thesis examiner: University of sydney

Member: Brazil Regional Reference Group (AnU)

Participant: scientists in schools participant

Australasian neuroscience society delegate: science meets Parliament

Australasian neuroscience society delegate: science technology Australia

AnU Representative: Australian Medical schools Assessment collaboration (AMsAc)

Interviewer: AnU Medical school Admissions

exam committee member: Year 1 and Year 2, AnU Medical school

committee member: JcsMR Group Leaders Forum

committee Member: Medical science theme, AnU Medical school

Year 1 exam committee member: AnU Medical school

Professor Thomas PreissMember: Australian society for Biochemistry and Molecular Biology

chair: RNA network Australasia, an AsBMB sIG

Member: Australasian Microarray & Associated technologies Association

Member: German society for Biochemistry and Molecular Biology

Member: AnU Major equipment committee

Member AnU Regional Reference Group europe

Member early career Academic Development committee cMBe/AnU (since 2014)

Member: JcsMR external Relations committee

Member: JcsMR Group Leaders’ Forum

Deputy chair: Research committee cMBe/AnU

nHMRc Panel Member: GRP2a

Grant-Assessor for ARc, national Heart Foundation, clive and Vera Ramaciotti Foundation, sylvia and charles Viertel Foundation, Marsden Fund (nZ), swiss national science Foundation, Austrian science Fund (FWF), cancer Research UK, nsF (UsA), French national Research Agency (AnR), and european Research council

cAP committee/ (PhD) thesis examiner: UnsW, University of sydney, University of newcastle, UQ, UWA

editorial Board Member: PLoS ONE

editorial Board Member: FEBS Open Bio

Reviewer: Cell, Science, Nat Cell Biol, PLoS Biol, EMBO J, TIBS, Genome Biol, NAR, RNA

co-convenor, session chair and speaker: eMBL Australia PhD course, canberra, Act

organising committee member: 1st Joint Australia Japan RnA Meeting, sydney, nsW

Programme co-chair: comBio 2014, canberra, Act

Ms Anne PrinsPresenter and Participant: national Youth science Forum, JcsMR, AnU, canberra, Act

Presenter and Participant: JcsMR open Day

Presenter and organiser: surgical cut Up Workshops, cIt Bruce, Act

Invited speaker: Heparan sulfate staining in Type 1 Diabetes Research Victorian Histology Meeting, Hobart, tAs

Anatomical Pathology Demonstrator: University of canberra, Bruce, Act and canberra Institute of technology, Bruce, Act

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82 the John curtin school of Medical Research

Professor Jan ProvisMember: scientific Advisory of the ophthalmic Research Institute of Australia (oRIA)

Member: scientific Advisory, eyeco Australia Pty Ltd

chair: Research Grants Advisory Group, Retina Australia

Associate Dean: teaching & Learning, AnU Medical school

sub-Dean: AnU Medical school, Acton campus

Member: Australasian neuroscience society (Ans)

Member: Association for Research in Vision & ophthalmology (ARVo)

Member: scientific Review of Progress – clemcell Project, Bond University.

Member: Bendigo Bank scholarship Advisory Group, Braidwood-Bungendore District. these scholarships are for students entering tertiary education and are in need of and eligible for financial support.

Dr Charani RanasingheVolunteer worker: Belconnen Art centre

Member and Volunteer worker: AIDs Action council Act

Member: Australasian society for Immunology

Member: society for Mucosal Immunology

Act Representative: AsI Mucosal Immunology special Interest Group

President: AsI Mucosal Immunology special Interest Group

Dr Danny RangasamyGrant Assessor: nHMRc

editoral Board Member: Solid Tumor; Biotechnology Letters

Member: Australian society for Biochemistry and Molecular Biology (AsBMB)

Dr Stuart ReadMember: International society of transgenic technologies (Istt)

Member: Australian society for Medical Research (AsMR)

Member: Australian new Zealand Laboratory Animal Association (AnZLAA)

session chair: Asian Mouse Phenotyping consortium student Workshop, canberra, Act

Dr Jennifer RobertsonPresenter and Participant: JcsMR open Day

Member: Australasian neuroscience society

Presenter and Participant: Act Government Women’s Day event, the John curtin school of Medical Research, AnU, canberra, Act

Presenter and Participant: UnisA students Visit, the John curtin school of Medical Research, AnU, canberra, Act

Dr Charmaine SimeonovicMember: Australasian society for Immunology

Member: transplantation society of Australia and new Zealand.

Member: transplantation society (International).

Member: International Pancreas and Islet transplant Association.

Member: Immunology of Diabetes society (International)

Member: International Xenotransplantation Association

Member: cell transplantation society

Member: Australian Diabetes society

Member: Islet society

Dr Tatiana SobolevaVisiting scientist: telopea Primary school, Barton, Act as part of the scientists in schools program, csIRo, canberra, Act

Ms Rina SoetantoPresenter: AnU 3-Minute thesis competition: Mending a broken heart- a big role for small RNAs, AnU, canberra, Act

Presenter: the science show, ABc Radio national: Mending a broken heart- a big role for small RNAs

treasurer: Australian society for Medical Research (AsMR), Act branch

organizing committee Member: eMBL Australia PhD symposium

organizing committee Member: the John curtin Association of Research students (JARs)

Reviewer: the AnU Undergraduate Research Journal

Member: Australian society for Biochemistry and Molecular Biology (AsBMB)

Member: the RnA society

Dr Zan-Ming Songeditorial Board Member:  Scientific World Journal (Neuroscience Section; Open Journal of Applied Sciences

co-chair: Block 5 of MchD medical curriculum, AnU Medical school, the Australian national University, canberra, Act

Professor Greg StuartInstructor and presenter: Australian course in Advanced neuroscience, north stradbroke Island, QLD

convenor: Australian Brain Bee challenge, Act Regional Finals, JcsMR, canberra, Act

Associate editor: Frontiers in Cellular Neuroscience

Advisory editorial Board: Trends in Neurosciences

council Member: sydney chapter of the American society of neuroscience

Member: Australasian neuroscience society

Member: Australian Academy of science

Member: society for neuroscience (UsA)

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Annual Review 2014 83

Dr Norimitsu SuzukiDemonstrator: Australian course in Advanced neuroscience, Moreton Bay Research station, north stradbroke Island, QLD

Presenter and Participant: national Youth science Forum, JcsMR

Member: Australasian neuroscience society

Member: society for neuroscience (UsA)

Dr Rebecca SweetMember: Australian society for Medical Research

Member: Australasian society for Immunology

Member: the American Association of Immunologists

Dr Malinda Tantirigama Member: Australasian neuroscience society

Member: society for neuroscience (UsA)

Presenter and Participant: JcsMR open Day

Professor David Tremethickcommittee member: Act branch of the Australian society for Medical Research

Act representative: the Australian society of Biochemistry and Molecular Biology

editorial Board Member: Chromosoma; Epigenetics; Epigenetics & Chromatin; Open Biology

Member: Lorne Genome society

Member: Australian society for Biochemistry & Molecular Biology

Member: American society for Microbiology

stream coordinator: comBio conference, canberra, Act

Dr Krisztina Valterchair: AnU Medical school Foundation Block, AnU, canberra, Act

chair: JcsMR Workplace Health & safety committee    

Founding Member: AnU education Fellowship scheme committee

Member: AnU Medical school Research Project committee

Member: Year 1 and Year 2 examination committees, AnU Medical school, AnU, canberra, Act

Member: Phase 1 curriculum committee, AnU Medical school, AnU, canberra, Act

Member: Medical science committee, AnU Medical school, AnU, canberra, Act

Member: neuroscience Discipline committee, JcsMR, AnU, canberra, Act

Member: Association for Research in Vision and ophthalmology (ARVo)

Member: european Vision and eye Research (eVeR)

Member: International society of ocular cell Biology (IsocB)

Member: Australasian neuroscience society (Ans)

Member: Australia and new Zealand Association for clinical Anatomists (AnZAcA)

Member: International Association for Medical education (AMee)

Presenter and Participant: national Youth science Forum, JcsMR, AnU, canberra, Act

Presenter and Participant: Indigenous student open day, AnU Medical school, AnU, canberra, Act

Participant: Bioscience teaching in Allied Health Working Group cUBe net

Participant: scientists and Mathematicians in schools 

Ms Tatiana VassilievaPresenter and Participant: JcsMR open Day

Mr Jorge VelezReviewer: Revista colombiana de estadística (colombian Journal of statistics), Department of statistics, national University of colombia at Bogotá; Revista comunicaciones en estadística communications in statistics Journal); Revista DYnA (Dyna Journal), Faculty of Mines, national University of colombia at Medellín; Revista de Ingeniería (engineering Journal), University of Antioquia, Medellín, colombia

Professor Carola G VinuesaMember: Australasian society of Immunology

Member: American Association of Immunologists

Member: nHMRc Women in Health and science Research (WiHs) working committee

scientific Advisory Board Member: sylvia and charles Viertel Foundation

WHo Advisor: Department of Reproductive Health

Advisory Board Member: Autoimmunity center of excellence, BIIR center for Inflammation & Genomic Medicine, Baylor Institute, Dallas, tX, UsA

Member: JcsMR executive committee

ec scientific Advisory council Member: sYBILLA european community Program ‘system Biology of t cell activation in Health and Disease’

Dr Harpreet VohraWorkshop and Lecture Host: Master of Biotechnology students, AnU, Bio-Medical Imaging students, Research school of engineering, AnU, Immunology students, Uc, Molecular and cell biology students, Uc, Biol3190 and BIoL3144 students, AnU

Presenter: Australian cytometry society Meeting, Gold coast, QLD

Dr Hilary WarrenAudio Describer: Vision Australia

Ms Belinda WhittleMember: the Australian Genomics technologies Association

session chair: Asian Mouse Phenotyping consortium student Workshop, canberra, Act

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84 the John curtin school of Medical Research

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Annual Review 2014 85

Support to JCSMR 2014Grant success

Financial overview

Donors to JcsMR

Report from the John curtin Medical Research Foundation

our corporate sponsors

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86 the John curtin school of Medical Research

GRAnts

ACT Chief Minister - Treasury and Economic Development Directorate

Professor C Parish and Professor R Hannan

centenary chair in cancer Research

$500,000

Australian Centre for HIV and Hepatitis Virology Research Grant

Dr A suhrbier, Professor e Gowans, Dr C Ranasinghe and Dr K Wagstaff

Validation of an effective HIV vaccine for pre-clinical evaluation

$165,000

Dr C Ranasinghe and Dr A suhrbier

ecoHIV -a convenient biosafety Level 2 mouse model for animal testing of HIV vaccines and anti-retroviral drugs

$22,900

Australian National University Major Equipment Committee Award

Professor J carver, Professor G otting, Professor D Tremethick, Dr D Hall and Associate Professor M CasarottoFoundation of a Quantitative Bio-molecular Interactions Analysis Facility

$95,000

Professor S Easteal, Associate Professor M Arcos-Burgos and Dr C Mastronardi Robotics to Prepare Human samples for Genome sequencing

$165,000

Associate Professor G Huttley, Professor J Borevitz, Professor S Easteal, Professor c Moritz and Dr S Foret Genome Diversity of Australia

$110,000

Australian Research Council Centre of Excellence

Professor G Stuart, Associate Professor E Arabzadeh, Professor M Ibbotson, Professor P Martin, Professor s Petrou, Professor s skafidas, Professor M Rosa, Professor J Mattingley, Professor PA Robinson, Professor AJ Lowery, Professor G Paxinos, Associate Professor U Grunert, Professor G egan, Professor P sahIntegrative Brain Function

$292,133

Australian Research Council Discovery Project Grants

Associate Professor E Arabzadeh

sensory integration in the whisker pathway: cortical transformations and the neuronal mechanisms that underlie decision confidence

$115,000

Dr VR Daria Four-dimensional analysis of information processing in brain circuits

$255,000

Dr VR Daria, Associate Professor C Stricker, Professor S Redman, Professor H Bachor and Professor G StuartUsing light to probe brain activity in 3D

$140,000

Professor A Dulhunty, Dr n Beard and Dr F Protasicalcium signalling by intracellular calcium stores in rabbit, mouse and man: Implications for muscle performance and athletic ability

$145,000

Professor S Easteal and Professor nG MartinVariation in the arginine vasopressin 1a receptor gene in the social environment and health

$112,000

Professor T Preiss tracking factor footprints to reveal the intricacy and control of translation initiation

$110,000

Dr D Rangasamy and Professor Je DahlstromUnderstanding the role of endogenous siRnAs in the maintenance of genomic defences

$70,000

Professor D TremethickUnderstanding how dynamic changes in chromatin composition control genome function

$182,000

Australian Research Council Future Fellowship

Associate Professor E Arabzadeh neuronal and behavioural correlates of sensory adaptation

$177,397

Australian Research Council Linkage Project

Professor T Maddess, Professor G Stuart, Dr A James and Dr B McGrathcreating new methods to study structure vision

$180,762

Bayer CropScience LP

Professor J Gready

Development of AnU technology for the design of variant Rubisco proteins with improved catalytic activity

$589,287

Belgian Science Policy Office InterUniversity Attraction Poles Programme Grant

Professor CG Vinuesat lymphocytes: from basic biology to immunotherapy

$10,100

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Annual Review 2014 87

Bioplatforms Australia Ltd National Collaborative Research Infrastructure Scheme

Professor D Tremethickemerging Biomolecular Platforms and Informatics Project

$450,000

Cancer Australia

Dr A Blackburn and Professor P Boardtargeting of two aspects of metabolic (totAM) for cancer therapy

$3,560

Commonwealth Department of Education Collaborative Research Infrastructure Scheme

Dr S WinsladeAustralian Phenomics network

$1,566,666

Commonwealth Department of Health

Associate Professor B Lidbury and Dr T Badricknovel quantitative methods that enhance clinical decision support based on routine pathology testing

$53,900

Department of Industry, Innovation, Climate Change Science Research and Tertiary Education (DIICCSRTE) Australia-India Strategic Research Fund

Professor P and Dr n LenkaAn insertational mutagenesis approach to identify epigenetic factors that control embryonic stem cell differentiation

$82,559

Department of Industry, Innovation, Climate Change Science Research and Tertiary Education (DIICCSRTE) National Collaborative Research Infrastructure Scheme

Professor Simon EastealAustralian national University Major open Data collections Project

$200,000

Dr S WinsladeAustralian Phenomics network

$1,325,815

Genentech

Dr S WinsladeGenentech Research collaboration and exclusive License Agreement

$1,171,000

Grains Research and Development Corporation (GRDC)

Professor J GreadyIdentification of superior Rubiscos in Wheat Relatives and lntrogression into elite Wheat

$750,000

Heart Foundation Grant-in -Aid

Professor C Hill, Professor K Matthaei, P Hansen, G Drummond, M esler and B Kemp-Harper treating therapy resistant hypertension: A role for atypical gated calcium channels

$65,000

Human Frontier Science Program

Dr R Sweetthe role of t cell derived interferon gamma in lupus associated anxiety and depression

$77,550

Ian Potter Foundation

Associate Professor I CockburnIntra-vital microscopy for research into infectious disease, cancer and autoimmunity

$50,000

Melanoma Institute Australia

Mr M FieldVirtual Genomics Laboratory

$75,000

MuPharma Pty Ltd

Dr C Ranasingheevaluation of a novel mucosal vaccine delivery device

$49,295

National Health & Medical Research Council Australia Fellowship

Professor CC Goodnownew strategies to reveal the genetic and cellular basis of immunological disease

$800,000

National Health & Medical Research Council Career Development Fellowships

Dr N Beardcontrol of cardiac and skeletal contractility by luminal calcium store load in health and disease

$96,040

Dr A EndersInvestigating B cell development maintenance and high-affinity antibody production by enU mutagenesis

$101,220

National Health & Medical Research Council Early Career Fellowships

Dr N BeveridgeRnA methylation and microRnA function in eukaryotic RnA

$76,149

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88 the John curtin school of Medical Research

Dr J ReedMechanisms of anti-Ro60 autoantibody-mediated tissue injury in congenital heart block

$76,419

National Health & Medical Research Council Equipment Grants

Dr M CasarottoWyatt QeLs-Quasi-elastic Light scattering Accessory

$32,240

Dr A Enders561nm yellow green laser for flow cytometry

$31,000

Professor D TremethickQuantstudio 3D Digital PcR system

$37,199

National Health & Medical Research Council Postdoctoral Training Fellowships

Dr J Ellyardthe effect of follicular helper t cells on AID regulation and selection of high affinity germinal centre B cells

$20,375

Dr I ParishRegulation of cD8+ t cell dysfunction during tolerance and chronic viral infection

$77,718

National Health & Medical Research Council Postgraduate Scholarship

Dr S Jiangthe effect of single nucleotide polymorphisms on immune regulation and the development of systematic lupus erythematosus

$48,956

National Health & Medical Research Council Program Grants

Professor R Hannan, R Hicks, RB Pearson and G McArthuroncogenic signaling and cancer therapy

$350,000

Professor c MacKay, Professor J sprent, Professor CC Goodnow, Dr F MacKay, Professor CG Vinuesa, Professor A Basten, Professor B Fazekas de st Groth, Dr s tangye and Dr R BrinkMolecular and cellular studies of the adaptive immune response in health and disease

$1,086,841

Professor C Parish, Professor B chong, Professor LM Khachigian and Professor R stockernovel Mechanisms Molecular targets and therapies in cardiovascular Disease

$386,682

National Health & Medical Research Council Project Grants

Associate Professor E Arabzadehneuronal substrate of choice in the Rat Whisker system

$128,094

Professor JM Bekkers and Dr Mark McDonnellPersistent firing in cortical interneurons: mechanisms and potential anticonvulsant role

$144,302

Professor PG BoardGlutathione transferase Zeta: A novel regulator of glucose and lipid metabolism

$196,084

Professor P Board, Dr A Blackburn and Professor J DahlstromPrevention of drug toxicities with dichloroacetic acid - the implication for cancer chemotherapy

$186,332

Professor PG Board, Professor AF Dulhunty, Dr MG Casarotto and Professor L Arnoldanew cardiac ryanodine receptor inhibitors for the treatment of heart failure

$197,244

Professor s Broer, Dr A Enders and Associate Professor R callaghanPhospholipid dependent signaling in B-cells

$146,725

Associate Professor M Casarotto, Professor J Dahlstrom, Professor A oakley and Dr s Raoepigenetic regulation by lysine specific demethylases in human breast cancer stem cells

$22,881

Professor M Cook, Dr D tscharke, Professor C Goodnow and Dr D FulcherGenomic medicine for human immune deficiency

$167,123

Professor AF Dulhunty, Professor L Arnolda, Dr A Blackburn and Dr N Beard Anthracyclines disrupt ca2+ signalling in cardiomyocytes: a contribution to cardiac toxicity

$148,775

Professor AF Dulhunty, Dr MG Casarotto and Professor PG BoardDHPR β subunit binding to a variably spliced region of RyR1: A role in ec coupling and myotonic dystrophy

$178,902

Professor AF Dulhunty, Dr MG Casarotto, Professor PG Board and Professor A oakleyInteraction between the alpha and beta subunits of the DHPR- a missing link in skeletal muscle excitation contraction coupling and a role in sarcopenia

$222,475

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Annual Review 2014 89

Professor S Easteal, Dr n cherbuin, Professor M Arcos-Burgos and Associate Professor G Huttley Haplotype variation at the dopamine transporter gene [sLc6A3]: function endophenotypes cognition and ADHD

$198,336

Dr K HorikawaAntigen receptor as oncogene: Understanding cARD11 mutations in B cell malignancy

$195,801

Associate Professor G Huttley and Dr W MeyerUncovering the genetic basis of fungal virulence

$82,893

Professor J Licinio, Professor M Arcos-Burgos, Associate Professor G Huttley, Professor S Easteal, Professor B Raphael, Professor nG Martin and Professor M-L WongGenetic variants and environmental factors in depression

$141,498

Professor JP Mackay and Dr D Ryan structural and functional analysis of a cancer-linked co-regulator complex

$15,000

Professor T Maddess, Dr F Sabeti, Dr C Carle, Associate Professor AC James, Professor J Provis and Dr R essexnovel functional testing for macular degeneration

$170,854

Professor T Preisscharacterising the topology and function of the human m5c RnA methylome

$206,056

Professor T Preiss and Dr J Clancyexploring the role of miRnA and target processing variability in cardiac hypertrophy

$194,895

Professor T Preiss and Professor M Hentze charting the interface between cellular metabolic states and gene regulation

$210,217

Dr C Simeonovic and Professor s BornsteinImpact of islet beta cell heparan sulfate in type 2 diabetes

$148,636

Dr C Simeonovic, Professor C Parish and Professor s BornsteinMechanism of protection of islet beta cells from t1D by heparan sulphate

$198,678

Professor GJ StuartImpact of inhibition on brain function

$203,732

Professor DJ TremethickHow our genome is regulated to determine cell function

$216,864

Professor DJ TremethickA new function for histone variants in the tissue-specific regulation of pre-mRnA splicing

$211,864

Dr K Valter- Kocsi, Professor J Provis, Professor P Gatenby and Dr M MadiganFighting age-related macular degeneration by reducing inflammatory events

$170,695

Professor CG Vinuesa and Dr J Ellyardnovel pathways that regulate t cells

$208,742

Professor I Young and Professor P Fostertargeting miRnA to inhibit leukocyte differentiation: a novel anti-inflammatory approach for the treatment of asthma

$96,835

Professor I Young, Professor D ollis and Dr J Murphycytokine-driven allergic inflammation: characterization of two isoform-specific

modes of IL-3 receptor activation and investigation of new receptor-associated signalling partners

$199,895

National Health & Medical Research Council Research Fellowships

Professor C Vinuesa$132,903

National Institutes of Health (US) Project Grants

Professor C Goodnow, Associate Professor G Karupiah, Dr E Bertram and Professor R Ulevitchsystems approach to immunity and inflammation

$802,954 (in conjunction with the scripps Research Institute)

Professor C Goodnow, Professor R Ulevitch and Professor B Beutlercore A: Genetics

$630,442 (in conjunction with the scripps Research Institute)

Professor C Goodnow, Professor R Ulevitch and Professor B Beutlersystems approach to immunity and inflammation - Annotation

$128,418 (in conjunction with the scripps Research Institute)

Professor T Lambshort-term adaptations in photoreceptors

$44,280

Perpetual Trustees Australia

Associate Professor Ian CockburnDevelopment and testing of a chemically attenuated whole parasite malaria vaccine

$100,000

Vasculitis Foundation

Professor C Vinuesa and Dr G Waltersthe role of microRnA in a novel mouse model of vasculitis

$50,000

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90 the John curtin school of Medical Research

FInAncIAL oVeRVIeW

Staff numbers 2013 2014

Academic staff * 75.1 72.75

General staff — administration, technical & support *º 140.45 139.44

HDR students (eFtsL) 81.0 73.56

Postgraduate coursework students (eFtsL) 11.1 8.38

Undergraduate students 23.9 22.38

* The figures are for full Time Equivalents, as at 31 december, and exclude casualsº includes Animal service facility staff

Recurrent and Special Purpose Funds $Total Income 2013 2014

student Fees 464,760 319,380

other Income 23,595,143 20,649,445

Internal sales 3,986,467 4,409,951

transfer from other 6,419,273 1,514,428

Internal Allocations 2,495,286 2,854,129

operating Grant 17,930,737 17,330,125

Investment Income 59,501 332,507

total Income 54,951,167 47,409,964

Total Expenditure

salaries & Related costs 24,999,564 25,149,425

equipment - capital 4,309,383 2,497,909

equipment - non-capital 533,048 491,920

scholars expenses 902,531 804,195

Utilities & Maintenance 2,766,480 2,895,152

travel Field & survey expenses 789,586 700,655

expendable Research Materials 8,788,626 8,036,658

other expenses 8,238,979 5,816,066

transfer to other 7,661,040 4,369,186

total expenditure 58,989,238 50,761,167

Net Current Year Operating Result 4,038, 070 3,351,203

Prior Year cash Result 21,225,223 17,683,730

Net Operating Position 17,187,153 14,332,528

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Annual Review 2014 91

DonoRs to tHe JoHn cURtIn scHooL oF MeDIcAL ReseARcH

the Director, staff and students of JcsMR thank all those friends and donors who so generously supported our work during 2014.

their Gifts and bequests to the school are being used to fund vital medical research projects as well as providing scholarships and purchasing specialised equipment.

If you would like to support our research, please consider a gift or bequest to fund a particular research project, scholarship or prize.

If you would like to discuss options for supporting JcsMR, please contact:

Dr Madeleine Nicol

t 02 6125 2577

e [email protected]

the estate of the Late Ms Dulys Anscombe

Mr stephen Barrett

Bowfate Pty Ltd

Mr Mark Bruce

canberra Medical society

club Jervis Bay

Ms Joanne Donnelly

Miss Rachel Feeney

Mrs Gwenyth Hallows

Dr Kevin Harding

Mrs Bev Harvey

Mr Kieren Harvey

Mrs Marie Hotchkiss

John James Foundation

Mrs Robyn Jones

Mrs Yvonne Keen

Mr Michael King

Mrs thelma Maurice

Ms Jennifer Mceniery

Ms Heather McLoughlin

Mrs Annmarie McQuarrie

Mrs Frances and Mr James Mifsud

Mr John nagle

Mr Kevin nguyen

Mrs Rhonda Robinson

Mr Gordon and Mrs Barbara Rogers

Rotary club of Goulburn, Mulwaree

sarcoidosis Australia

Mr Robert schutz

Mrs Diana scudamore

Mr Dominic staun

Mrs Helene stead

Miss tracey stevenson

Ms sue sullivan

the sarah-Grace sarcoma Foundation

Mr Robert tupper

Mr thomas and Mrs Jenny tyrrell

Ms Debbie Vipond

the estate of the Late Dr Gwendolyn Woodroofe

Mr Robin Yule

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92 the John curtin school of Medical Research

tHe JoHn cURtIn MeDIcAL ReseARcH FoUnDAtIon – RePoRt to DonoRs 2014

our thanks go to those who have so generously supported the John curtin Medical Research Foundation at AnU during 2014

2014 was a very successful year for the John curtin Medical Research Foundation, with many goals achieved.

the highlight of the year was our second Annual Dinner, at which nobel Laureate Professor Robin Warren was our special guest. nearly 200 attendees heard Professor discuss the science that led to his and Professor Barry Marshall’s discovery of the Helicobacter pylori as the cause of peptic ulcers.

the 2nd Annual Dinner also saw the Foundation achieve its goal of purchasing a $1.2M intra-vital microscope for the John curtin school of Medical Research, thanks to generous donations on the night from the John James Foundation, and Janice and Ron Parker. the Board is very grateful for all the donations it has received over the past two years culminating in this purchase.

We were also able to produce three high quality newsletters throughout 2014, which highlighted the excellence of medical research at AnU. I would particularly like to thank Ken Begg, Dr Peter Jeffrey and Dr Madeleine nicol for their superb efforts in producing the newsletter, which was very favorably received by the public at large.

Another 2014 highlight for the Foundation was the announcement that Professor Ross Hannan had been appointed as the first centenary chair of cancer Research at the John curtin

school of Medical Research. the Foundation played a very significant role in achieving $1.5M in support from the Act Government to partner with AnU in this appointment.

In February 2014 the national centre for Indigenous Genomics was launched at JcsMR. the canberra Medical society, which has been involved in Indigenous health projects for over a decade, donated $34,000 to support the ncIG and their important work. the cMs, in conjunction with JcMRF will host “sunday Dreaming” on the grounds of Government House in May 2015, in order to raise further funds and increase awareness about the work of the ncIG.

the Foundation has greatly enjoyed engaging with all those donors who have supported our projects, and medical research at AnU throughout 2014.

I would like to thank each of those donors on behalf of the Board for their passion for life changing medical research, and their generosity.

Dr Cameron Webber OAM

chair – the John curtin Medical Research Foundation

For further information please see: jcmrf.anu.edu.au

Donors to The John Curtin Medical Research Foundation 2014Dr Mohammed Alsalami AM

Mr Michael calkovics

Dr Kee cheung oAM

Mrs connie clancy

Mr Bob cotton

the tom efkarpidis Foundation

Ms Rosmery Franco

Mr Denis Gilmour

Ms Wendy Gray

Mr Paul Greenhalgh AM

Ms Mary Humphries

Mr David Hunt

John James Foundation

Mr David Kennemore

Mr Paul Kitney

Dr Lachlan Lewis

Professor Masayuki Miyasaka

Mr Ron and Mrs Janice Parker

Mr Brian and Mrs Margaret Parry

Mr Graham and Mrs Gail Potts

Mr Gary and Mrs Marianne Robb

Mr Bert Roberts

Mrs Helen todd

Dr Fred tosolini

Mr tony and Mrs Lorna Ward

Mrs Ilona White

Mr George Wyer

Mrs Margaret Yeung

the Board would also like to thank all those who volunteered their time and expertise, provided prizes for our fundraising events, and supported the Foundation throughout 2014.

Ms Helen Aitken-Kuhnen

Mr Martin and Mrs susie Beaver – the Beaver Galleries

Bilk Gallery

Mr Rodney and Mrs Michele Black

Boffins Restaurant, University House

the Brassey Hotel

Burbury terrace, the Burberry Hotel and Apartments

Bunnamagoo Wines, Mudgee

capital eye

creations Jewellers Manuka

Ms Marilyn Fenner

Focus on eyewear

Ms Donna Gibbons

Home by creations Manuka

Ms Gina Jeffrey

Malamay

Mania Manuka

Marshall surf Design

Ms Lynne Mills

Mont Adventure equipment

Ms Rhonda Robinson

Mrs Joanna Webber

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coRPoRAte sPonsoRs

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the John curtin school of Medical Research AnU college of Medicine, Biology and environment 131 Garran Road Acton Act 2601 Australia

t +61 2 6125 2550 F +61 2 6125 2337 e [email protected] W jcsmr.anu.edu.aucRIcos #00120c

Mo

_140

180