annualscientific 2007 - british cardiovascular society programme 2007.pdfbritish cardiovascular...

2007 Annual

ScientificConference

Programme4-7 June 2007 SECC, Glasgow

British Cardiovascular Society Annual Scientific Conference 4-7 June

Contents

1

New members 2

General information 3

Exhibition 4

Committee meetings 5

BCS Board and Council 6

Joint committees 6

BCS committees 7

Abstract markers 8

Affiliated groups 9

Programme at a glance (Trainees’ day – 4 June) 12

Programme details 14

Programme at a glance (CPD day – 5 June) 20


Programme at a glance (CPD and research day – 6 June) 34


Programme at a glance (CPD and research day – 7 June) 76


Author index 106

Floor plan and map Backcover

Page

On behalf of the Programme Committee and the Affiliated Groups of theBCS, I should like to extend a very warm welcome to you. The 2007 meetingof the BCS has been planned to give a wide spectrum of cardiovasculareducation and research presentations to all the groups that attend. Following last year’s meeting, the Programme Committee received somevery helpful feedback and we have tried to respond to this where possible.

This year we are marking the new name of the BCS – now the BritishCardiovascular Society which has evolved from 60 years of the BritishCardiac Society. On Monday evening, in place of satellite symposia, there will be a BCS symposium marking achievements of British cardiovascularscience and looking to what the future may hold. This will be followed by a reception in the Exhibition area to which you are all invited.

This year, the number of moderated posters has been expanded and therewill be basic and clinical presentations in the Exhibition Hall on each day of the meeting. These are amongst the highest scoring abstracts andrepresent some very stimulating research. I strongly encourage you to take a look at these. The posters will be presented at the morning coffee breaks.

This year, the Lomond Hall is fitted out with key pads to allow audienceparticipation with the sessions (and will also be used at the AGM). Speakersin the Lomond may build questions into their talks and it is hoped that you will find this adds to the educational value of the sessions held there.

The Exhibition is a central part of the meeting. The Programme Committeehas asked exhibitors to extend as much as possible the educationalopportunities on their stands and some of these will be highlighted duringthe meeting.

I hope you have a stimulating and rewarding meeting.

On behalf of the BCS, welcome to Glasgow.

David CrossmanChairman of the Programme Committee

Published by the British Cardiovascular Society, 9 Fitzroy Square, London W1T 5HWTel: +44 (0)20 7383 3887 Fax: +44 (0)20 7388 0903

Company Limited by guarantee. Registered in England No. 3005604. Registered Charity No.1093321

3

General information

Conference

The conference will be held in the Scottish Exhibition and Conference Centre (SECC). The programme will open on Monday 4 June at 09.15 hrs and close on Thursday 7 June at 13.30 hrs.

Exhibition

The exhibition will be held in Hall 4 and will be open from 14.30 hrs on Monday.

Registration

Registration will take place in Hall 4. Desks will be open at the following times:

Monday 4th June 08.00 – 20.30

Tuesday 5th June 07.30 – 18.00

Wednesday 6th June 07.30 – 18.00

Thursday 7th June 07.30 – 13.30

See the back cover of this programme for a location plan of the meeting rooms and exhibition hall.

Delegate badges

White BCS Member

Blue Affiliated Groups

Red Non member

Green Presenter/Chairman

Black BCS Staff

Yellow Sponsored symposium only

Badges must be worn at all times to gain admission to sessions, exhibition hall, annual dinner and other events.

The audiovisual centre will be located in the Morar Room in the Seminar Suite.

CPD – the conference is registered with the RCP for CME/CPD.

Catering facilities are located in Hall 4 and on the main concourse. For those attending the‘How to’ sessions, a packed lunch will be available for purchase near the session rooms.

The contact telephone number at the registration desk during the conference is 0141 576 3405.


New members To be introduced at the AGM 2007

2

Dr M Alam

Dr M Alzetani

Dr A Amir

Dr R Ang

Dr P Atkinson

Dr S Babu-Narayan

Dr A Banerjee

Dr P Barlis

Dr P Barman

Dr D Barmby

Dr A Begg

Dr M Burke

Dr R Byrne

Dr A Chacko

Mrs C Chambers

Dr D Chatterjee

Mrs L Chew

Dr T Chico

Dr A Chikermane

Dr A Choy

Dr P Clift

Dr D Conway

Miss A Crundall

Dr N Dani

Dr D Dawson

Dr P De Silva

Dr S Dhar

Mrs C Eade

Dr L Erwin

Dr P Freeman

Dr A Gopalamurugan

Ms K Gordon

Dr B Grimaldi

Dr K Grosser

Dr M Gunning

Dr H Hadi

Dr M Hamilton

Dr A Harkness

Dr A Houghton

Dr T Ismail

Dr J Jagoda

Dr D Jones

Dr P Kanagaratnam

Dr G Kassianos

Prof B Keavney

Dr R Khamis

Dr A Khokhar

Dr P Knapton

Dr M Laher

Prof C Lang

Dr J D Lee

Dr J M S Lee

Dr K Lee

Dr L Lee

Dr C Lewis

Dr S Little

Dr P MacIntyre

Dr D Mack

Dr I Malik

Dr L Melley

Dr S Mohiddin

Dr C Monaco

Dr D Obaid

Dr B Oledzka

Dr T Pakrashi

Dr N Parchure

Dr R Patel

Dr J Payne

Dr S Petersen

Dr S Pettit

Mr M Pi

Dr B Prendergast

Dr V Puntmann

Dr I Ramzy

Dr V Rathore

Dr N Razvi

Dr I Roussin

Dr M Scoote

Dr R Sharma

Dr R Sharma

Dr A Shetty

Dr J Sobolewska

Dr M Sohal

Dr D Tharmaratnam

Dr G Welch

Dr S Williams

Dr F Witherow

Dr A Yavari

Dr A Yusuf

5

Committee meetings

MondayCommittee Room Time

SAC Business Etive 11:30

BJCA Council Fyne 12:15

Working Group on Women’s Heart Health Katrine 12:15

BCS hosts SAC meeting/STC chairs/TPDs Leven 13:30

BCIS Council Katrine 13:30

BSE Industry Fyne 14:30

NCASP Twice Yearly Heart Disease Meeting Ness 14:30

TuesdayCommittee Room Time

Service Network Advisors Dochart 07:30

JCAB Knowledge Based Assessment Fyne 07:30

BSE Council Ness 07:30

BCCA Council Katrine 08:00

Women’s Network Leven 13:00

Academic and Research Etive 13:00

BSCMR Fyne 13:00

BNCS Business Katrine 13:00

SCST Education Gala 13:00

BACR Council Ness 13:00

WednesdayCommittee Room Time

BCCA Business Meeting Ness 07:30

BANCC AGM Clyde 12:00

BSCMR AGM Hall 1 12:30

HCP (UK) Katrine 12:30

Trainee Education Fyne 12.45

HRUK Council Leven 12:45

BSH Board Ness 12:45

Information and Surveys Etive 13:00

BSH EGM Alsh 15:30


Exhibition

4

The Society would like to thank the many exhibitors who have purchased stand space. All delegates are encouraged to visit the exhibition, which will be open at the following times:

Monday 4th June 14.30 – 20.30

Tuesday 5th June 09.00 – 18.00

Wednesday 6th June 09.00 – 18.00

Thursday 7th June 09.00 – 13.30

Further information on this year’s exhibition may be obtained from Concorde Services Ltd (tel: 0141 331 0123; email: [email protected]).

Sponsored symposia

A number of companies are hosting sponsored symposia on Tuesday and Wednesdaylunchtimes and Tuesday evening.

Tuesday

Servier Laboratories Ltd – Heart rate: is our finger on the pulse?

Novartis – Winning the battle with difficult and resistant hypertension

Daichii-Sankyo/Lilly – Optimal antiplatelet treatment of ACS patients undergoing PCI

sanofi-aventis – Cardiovascular disease, abdominal obesity and the endocannabinoid system

Wednesday

Pfizer – Debate: Cholesterol targets of 4 and 2mmol/L should be national policy for patients with established CHD

Schering Plough/MSD – Balance: the art of cholesterol management

Annual dinner

The annual dinner will take place on Wednesday 6 June at the Kelvingrove Art Gallery.

7

BCS committees

Academic and ResearchCommitteeHugh Watkins (Chairman)Nicholas BoonRobin ChoudhuryDavid CrossmanDavid EisnerAdam FitzpatrickKevin JenningsMichael MarberNilesh SamaniPeter Weissberg Bindi Sheemar

Clinical Practice CommitteeSteven Bridge Nicholas Boon Nicholas Brooks Keith Dawkins David Hackett Guy Haywood Terry McCormack Peter Mills Charles Pumphrey Jillian RileyMark SignyKen Timmis Kirsten Bradbury

Elections CommitteeHuon Gray (Chairman)Jennifer Adgey Nicholas Brooks John CammCharles GeorgeDavid GeldardHoward SwantonAnna Kassai

Finance CommitteeKevin Jennings (Chairman) Nicholas Boon Nicholas Brooks John DeanfieldNicholas Kaye Graham Meek Paul Oldershaw Martin Rothman Tony SalterDerek YellonFinola McNichollBindi Sheemar

Industry Liaison CommitteeNicholas Brooks (Chairman)Chris BrinsmeadNicholas BoonNigel BrooksbyStephen BrownJackie GanleyDavid GeldardBeccy HolmbergKevin JenningsGeoff MorrisSatoru NoguchiTony Whitehead;Derek YellonFinola McNichollRosemary WestonSteven Yeats

Information and SurveysCommitteeSarah Clarke (Chairman)Stephen HolmbergIan CoxTim BowkerSaul Myerson Martin GodfreyStuart PringleDavid RobertsUsha PrasadKirsten BradburyAnna KassaiSteven Yeats

Programme CommitteeDavid Crossman (Chairman) Martin BennettNicholas Brooks Nicholas BoonBarbara CasadeiSarah ClarkeStuart CobbeAnthony GershlickDavid HackettStephen Holmberg Kevin Jennings Peter Mills Jeremy Pearson Bernard Prendergast Iain Simpson Derek Yellon Fiona McNicholl Mary-Lou Pitts Rosemary WestonSteven Yeats


BCS Board and Council

6

BOARD Position Appointed

Dr Nicholas Brooks President 2005-2007

Dr Nicholas Boon President Elect 2005-2007

Dr Stephen Holmberg Honorary Secretary 2006-2008

Dr David Hackett Vice-President Clinical Standards 2007-2010

Dr Kevin Jennings Vice-President Corporate and Financial Affairs 2006-2009

Dr Peter Mills Vice-President Training 2006-2007

Prof David Crossman Vice-President Education and Research 2003-2008

Prof Stuart Cobbe Vice-President Elect Training 2006-2007

Prof Dame Carol Black Non-executive Trustee 2007-2011

Mr Graham Meek Non-executive Trustee 2007-2011

COUNCIL 2007-2008

Heart Management Committee (BCS/BMJ Publishing)Nicholas Brooks (Co-Chairman)Stella Dutton (Co-Chairman)

Joint Specialty Cardiology Committee (BCS/RCP)David Crossman (Chairman)

Specialty Advisory Committee (BCS/RCP)Peter Mills (Chairman)

Joint committees

Nicholas Brooks (Chairman)Nicholas BoonRoger BoyleKeith ChannonJohn ClelandChris CloughStuart CobbeDerek ConnellyPeter CreanDavid CrossmanBernie DowneyFrank DunnDavid Eisner

Chris EggettJane FlintKevin FoxChris GaleDavid GeldardAnthony GershlickJohn GibbsPeter GrovesDavid HackettJim HallMark HarbinsonStephen HolmbergKevin Jennings

Ian JonesTerry McCormackAndrew McLeodPeter MillsCharles PeeblesDudley PennellJames RoxburghMark SignyMartyn ThomasAdam TimmisNeal UrenPeter Weissberg

9

Affiliated groups

British Association for Cardiac Rehabilitation (BACR)

President: Mrs Bernie Downey ([email protected])

Treasurer: Ms Carol Over ([email protected])

Secretary: Ms Judith Edwards ([email protected])

British Association for Nursing in Cardiac Care (BANCC)

President: Mr Ian Jones ([email protected])

President-Elect Ms Jenny Tagney ([email protected])

Treasurer: Mr Alun Roebuck ([email protected])

Secretary: Ms Rachel Matthews ([email protected])

Junior Secretary: Ms Jane Butler ([email protected])

British Atherosclerosis Society (BAS)

Chairman: Professor Keith Channon ([email protected])

Treasurer: Dr Chris Newman ([email protected])

Secretary: Dr Sarah George ([email protected])

British Cardiovascular Intervention Society (BCIS)

President Dr Martyn Thomas ([email protected])

Treasurer: Dr Simon Redwood ([email protected])

Secretary: Dr Bernard Prendergast ([email protected])

British Congenital Cardiac Association (BCCA)

President: Dr John Gibbs ([email protected])

Treasurer: Dr Joseph De Giovanni ([email protected])

Secretary: Dr Graham Stuart ([email protected])

British Junior Cardiologists’ Association (BJCA)

President: Dr Chris Gale ([email protected])

Treasurer: No appointment

Secretary: Dr Dawn Adamson ([email protected])


Abstract markers

8

Dr A Al-Mohammed

Dr F Astin

Dr A Bakhai

Dr A Banning

Dr K Barakat

Dr A Baumbach

Prof H Becher

Dr T Betts

Prof S Bhattacharya

Dr A Bishop

Dr R Bogle

Dr N Boon

Dr J Bourke

Dr A Brady

Dr C Brookes

Dr M Brown

Dr F Bu’Lock

Dr A Calver

Prof D Carling

Dr J Chambers

Dr R Clark

Prof K Clarke

Dr P Cowburn

Dr T Cripps

Dr P Daubeney

Dr G Davey-Smith

Dr W Davies

Dr D Dawson

Dr M de Belder

Prof C Deaton

Dr C Dickinson

Dr C Dollery

Prof A Dominiczak

Dr D Dutka

Ms L Edmunds

Dr M Farrer

Dr A Ferro

Dr D Francis

Dr P Fraser

Dr S Furniss

Dr M Gammage

Dr C Garratt

Dr M Gautel

Dr F Green

Dr J Greenwood

Dr M Griffith

Dr M Gunning

Dr H Hemingway

Dr R Henderson

Dr D Henderson

Dr M Kearney

Dr B Keavney

Dr P Kohl

Prof C Lang

Dr G Lloyd

Dr P Ludman

Dr P MacCarthy

Dr K MacLeod

Prof G Mann

Dr V Markides

Dr A Mathur

Dr J Mayet

Dr B Mayosi

Dr J McEwan

Dr P Munroe

Prof L Ng

Dr N Patel

Dr C Peebles

Dr D Pellerin

Dr B Pendergast

Prof D Pennell

Mr P Punjabi

Dr I Purcell

Prof T Quinn

Dr S Ray

Dr S Redwood

Dr C Redwood

Dr A Rozkovec

Dr N Sattar

Dr M Scheuermann-Freestone

Dr R Schilling

Dr R Senior

Dr L Shapiro

Dr A Slade

Dr D Sprigings

Dr A Stanley

Dr R Steeds

Dr A Struthers

Dr G Stuart

Ms J Tagney

Dr B Tan

Dr S Thorne

Dr J Townend

Dr V Tsang

Dr R Tulloh

Dr H Waterhouse

Dr N West

Prof M Wilkins

Dr S Williams

Dr S Woldman

Dr C Wren

Ms M Wrighley

Dr Q Xu

The Programme Committee wishes to acknowledge the generous help given in abstractselection by the following (names in bold indicate Chairmen of the markers for their category).

11

Heart Care Partnership UK (HCPUK)

Chairman andPresident: Mr David Geldard ([email protected])

Treasurer: Mr Ken Timmis ([email protected])

Secretary: Ms Anne Jolly ([email protected])

Heart Rhythm UK (HRUK)

President: Dr Derek Connelly ([email protected])

Treasurer: Prof John Morgan ([email protected])

Secretary: Dr Michael Gammage ([email protected])

Primary Care Cardiovascular Society (PCCS)

Chairman: Dr Terry McCormack ([email protected])

Chairman-Elect Dr Ahmet Fuat ([email protected])

Treasurer: Dr Stewart Findlay ([email protected])

Secretary: Dr Kathryn Griffith ([email protected])

Executive Director: Dr Fran Sivers ([email protected])

Society for Cardiological Science and Technology (SCST)

President: Dr Chris Eggett ([email protected])

Treasurer: Dr Leslie Goulding ([email protected])

Honouray Secretary: Mr Peter Lewis ([email protected])


Affiliated groups continued

10

British Nuclear Cardiology Society (BNCS)

President: Dr Mark Harbinson ([email protected])

Treasurer: Dr Simon Woldman ([email protected])

Secretary: Dr Catherine Dickinson ([email protected])

British Society of Cardiovascular Imaging (BSCI)

Chairman: Dr Charles Peebles ([email protected])

Treasurer: Dr Richard Coulden ([email protected])

Secretary: Dr Roger Bury ([email protected])

British Society for Cardiovascular Research (BSCR)

Chairman: Prof David Eisner ([email protected])

Treasurer: Dr Michael J Curtis ([email protected])

Secretary: Prof Barbara McDermott ([email protected])

British Society of Echocardiography (BSE)

President: Dr Kevin Fox ([email protected])

Treasurer: Mr Graham Leech ([email protected])

Secretary: Mrs Jane Allen ([email protected])

British Society for Heart Failure (BSH)

Chairman: Professor Martin Cowie ([email protected])

Treasurer: Dr Suzanna Hardman ([email protected])

Secretary: Ms Michelle Glanville ([email protected])

British Society of Cardiovascular Magnetic Resonance (BSCMR)

Chairman: Professor Dudley Pennell ([email protected])

Treasurer: Professor Henry Dargie ([email protected])

Secretary: Ms Michelle Glanville ([email protected])

1312

9.15

10.45

12.15

13.00

14.30

16.00

16.15

17.0017.15

19.00

20.30

SACInteractive meeting for trainees

in cardiology

BCISCase studies

BSE/BNCS/BSCMROptimising the use of multimodality imaging in cardiac patients. A case based approach

HRUKAssessing families at high risk

of sudden cardiac death

Strickland-Goodall LectureProf Keith Channon

Sixty years of UK contribution to cardiovascularmedicine – where in the future

Opening by the President Dr Nicholas Brooks

L u n c h

B r i t i s h C a r d i o v a s c u l a r S o c i e t y l a u n c h p a r t y

BSH/Diabetes UKDiabetes mellitus and heart failure

BASUpdate on platelets;drugs and receptors

BSCR/BSHIs the failing heart in need of more

energy?

L u n c h

B r i t i s h C a r d i o v a s c u l a r S o c i e t y l a u n c h p a r t y

AlshLomond


Trainees’ day Monday 4 June

Trai

nees

’ day

Mon

day

4 Ju

ne

Heart Failure Electrophysiology/pacing Intervention Imaging

15

Lomond (continued)

Primary PCI

SpR case presentation 3Dr Peter Henriksen

The evidence base for primary PCIDr Neal Uren

SpR case presentation 4Dr Jaydeep Sarma

Developing a service and optimising outcomeDr Nicholas Curzen

Audience and panel discussion

Alsh 10.45-12.15Teach-in

British Society for Heart Failure (BSH) / Diabetes UK

Diabetes mellitus and heart failure

Chair: Prof John Cleland and Dr Richard Holt

Molecular mechanisms linking diabetes and cardiovascular diseaseDr Peter Grant

Epidemiology and clinical pathophysiology Dr John Petrie

How to treat diabetes in patients with heart failure Dr Stephen Beer

Effects of treatment for heart failure in diabetes Dr Iain Squire

Lunch 12.15-13.00


Programme

14

Exhibition Hall, SECC 08.00-20.30Registration

Lomond 09.15-10.45Interactive SAC meeting for trainees in cardiology

Chair: Prof Stuart Cobbe and Dr Peter Mills

The 2007 curriculum – highlights for new and current traineesDr James Hall

Assessment in relation to RITA – when and howDr Ian Wilson

Selection and allocation into cardiology ST3 – understanding MMCDr Theresa McDonagh

Selection into subspecialties for cardiology NTN holdersDr Nick Curzen and Dr Saul Myerson


Lomond 10.45-12.15Teach-in

British Cardiovascular Intervention Society (BCIS)

Case studies

Chair: Dr Keith Oldroyd and Dr Neal Uren

Panel: Dr Andreas BaumbachDr Nicholas CurzenDr Keith OldroydDr Neal Uren

Stent thrombosis in the DES era

SpR case presentation 1Dr Arvind Sood

The drug-eluting stent trials – behind the dataDr Keith Oldroyd

SpR case presentation 2Dr Sachin Jadhav

Avoiding late stent thrombosisDr Andreas Baumbach


Trai

nees

’ day

Mon

day

4 Ju

ne

17


Heart Rhythm UK (HRUK)

Assessing families at high risk of sudden cardiac death

Chair: Dr Derek Connelly and Dr Clifford Garratt

Role of the pathologistDr Mary Sheppard

Role of the cardiologistDr Perry Elliott

Role of the electrophysiologistDr Andrew Grace

Role of the geneticistDr Edward Blair


British Society for Cardiovascular Research (BSCR)British Society for Heart Failure (BSH)

Is the failing heart in need of more energy?

Chair: Prof David Eisner and Prof Stefan Neubauer

Altered energy production in the failing human myocardium Prof Kieran Clarke

Remodeling energy production – salvation or damnation in heart failure? Dr Anne-Marie Seymour

Options for metabolic therapy in heart failure Prof Stefan Neubauer

Cardiac cachexia Dr Andrew Clark

Lomond 16.00-16.15Formal opening of the scientific sessions by the PresidentDr Nicholas Brooks


Programme

16


British Society of Echocardiography (BSE)British Nuclear Cardiology Society (BNCS)British Society of Cardiovascular Magnetic Resonance (BSCMR)

Optimising the use of multimodality imaging in cardiac patients. A case based approach

Chair: Dr Kevin Fox and Dr Peter Wilde

Ischaemic heart failure (TTE/DSE + CMR + Angio)Dr Francisco Leyva

Aortic valve disease (TTE + DSE + 64 slice CT)Dr Charles Peebles

A diabetic with raised BMI and atypical chest pain (MPS + angio)Dr Mark Harbinson

A case of congenital disease (echo/TOE +)Dr Navroz Masani


British Atherosclerosis Society (BAS)

Update on platelets: drugs and receptors

Chair: Dr Keith Oldroyd and Dr Robert Storey

Platelet biology and receptors: what makes them stick?Prof Stanley Heptinstall

Antiplatelet drugs, old and newDr Anthony Gershlick

What the future holds for antiplatelet treatments in clinical practiceDr Robert Storey

Exhibition opens 14.30

Trai

nees

’ day

Mon

day

4 Ju

ne

19


Programme

18

Lomond 16.15-17.00Strickland-Goodall LectureProf Keith Channon

Cardiovascular oxidants and antioxidants: What to stress?

Introduced by Dr Nicholas Brooks; Thanked by Prof Martin Bennett

Lomond 17.15-19.00Sixty years of UK contribution to cardiovascular medicine – where in the future?

ArrhythmiaProf John Camm

PopulationProf Rory Collins

Cardiac surgeryProf Sir Bruce Keogh

Myocardial infarctionProf Keith Fox

Heart failureProf Philip Poole-Wilson

Clinical translation of basic scienceProf Peter Weissberg

Exhibition Hall 4 19.00-20.30BCS Launch Party

Trai

nees

’ day

Mon

day

4 Ju

ne

20 21


CPD day Tuesday 5 June

CP

D d

ayTu

esda

y 5

June

BCISControversial issues

in angioplasty and abstracts

(1-2)

PCCS/BHSChallenges inhypertension

Sponsored symposiumServier Heart rate: is our

finger on the pulse?

BCS/ACCAvoiding complications

with cardiovasculardrugs

Paul Wood LectureProf Catherine Otto

Sponsored symposiumDaichii-Sankyo/LillyOptimal antiplatelet

treatment of ACS patientsundergoing PCI

BSH/BSCMRShould CMR be used routinely in

heart failure?

BSH/HRUKAtrial fibrillation in

heart failure

Sponsored symposiumNovartis Winning the battle with difficult andresistant hypertension

BSEMultimodality monitoring of valve disease

BHFAdult CV disease fromdevelopmental biology

BSENew techniques in

the echo lab

How to advise the patient with congenital heart

disease and their family

HRUK/PCCSAF and primary care

Sponsored symposiumsanofi-aventis

Cardiovascular disease,abdominal obesity and theendocannabinoid system

Exh ib i t ion break

BAS/BSCR/BCISEndothelial dysfunction and

thrombosis followingstenting: scientific and

clinical issues

Clyde Lomond Hall 1 Forth8.30

10.00

11.30

13.0013.15

14.1514.30

16.00

17.00

18.00

18.30

20.00

M o d e r a t e d p o s t e r s i n e x h i b i t i o n( 3 - 1 4 )

E x h i b i t i o n b r e a k

Exhibition break

BSCRVascular calcification

BACRPromoting physical activity in the

sedentary cardiac patient

How to follow up the patient with a prosthetic valve

BSH/BCCAThe right stuff

How to set up a primary angioplasty service

How to select patients for cardiac resynchronisation

therapy

Alsh Boisdale Carron

M o d e r a t e d p o s t e r s i n e x h i b i t i o n 3 - 1 4

E x h i b i t i o n b r e a k


Hall 1 08.30-10.00British Society for Heart Failure (BSH)British Society of Cardiovascular Magnetic Resonance (BSCMR)

Should CMR be used routinely in heart failure?

Chair: Prof Henry Dargie and Prof Dudley Pennell

What are the imaging issues in heart failure? Multimodality imaging or a ‘one stop shop’? Prof Stefan Neubauer

Measuring ventricular function in heart failure – CMR, the most accurate and reproducible method available Dr Robin Weir

‘Heart failure’ is an incomplete diagnosis: how CMR brings us closer to the truthProf Dudley Pennell

CHD is the commonest cause of heart failure – how reversible dysfunction can beidentified and quantifiedDr Stuart Watkins

The cardio-renal axis – une liaison dangereuse! Prof John Cleland

Forth 08.30-10.00British Heart Foundation (BHF)

Insights into adult cardiovascular disease from developmental biology

Chair: Prof Jeremy Pearson

Heart development and heart failureProf Shoumo Bhattacharya

Growing collateral vessels Dr Ferdinand Lenoble

Educating stem cells to mend a broken heartDr Paul Riley

23


Programme

22


Lomond 08.30-10.00British Cardiovascular Intervention Society (BCIS)

Controversial issues in coronary angioplasty in the UK

Chair: Dr Martyn Thomas and Dr Huon Gray

Diagnostic coronary angiography should only be performed by cardiologists trained in angioplasty? Dr Jim McLenachan

001

THE REACT TRIAL {RESCUE ANGIOPLASTY V CONSERVATIVE TREATMENT OR REPEAT THROMBOLYSIS} TRIAL: LONGER TERM FOLLOW UP

Gershlick, AH; Fairbrother, K; Carver, A; Stevens, S; Richardson, G

University Hospitals of Leicester, Leicester, United Kingdom

Tertiary v DGH PCI – is there a difference? Dr Peter Ludman

002

DELAYS IN DELIVERING PRIMARY ANGIOPLASTY WITH INTERHOSPITAL TRANSFERRESULT IN LIMITED MORTALITY BENEFIT IN REAL-WORLD PRACTICE IN THECONTEXT OF A HIGH QUALITY THROMBOLYSIS SERVICE

Dalby, MCD1; Kharbanda, RK1; Ghimire, G1; Spiro, J1; Hutchison, E1; Teoh, M2; Grocott-Mason, R2; Roughton, M1; Mitchell, AG1; Mason, M1; Ilsley, C1

1. Royal Brompton & Harefield NHS Trust, London, United Kingdom; 2. Hillingdon Hospital NHS Trust,London, United Kingdom

Should financial considerations influence decision making in revascularisation? Dr Steve Holmberg

CP

D d

ayTu

esda

y 5

June

005

MUTATIONS IN THE CARDIAC TRANSCRIPTION FACTOR TBX1 MAY CONTRIBUTE TOSUSCEPTIBILITY TO TETRALOGY OF FALLOT IN PATIENTS WITHOUT 22Q11 DELETION

Griffin, HR; Keavney, B; Goodship, J

CHANGE Study Group, The Institute of Human Genetics, Newcastle-Upon-Tyne, United Kingdom

006

ENDOTHELIAL PROGENITOR CELLS IN ADULTS WITH AND WITHOUT CORONARYARTERY DISEASE AND THEIR HEALTHY ADULT OFFSPRING: EVIDENCE FORPOTENTIAL GENETIC REGULATION

Whittaker, A; Moore, JS; Vasa, M; Stevens, S; Samani, NJ

Dept of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom

007

GENETIC DISSECTION OF A BLOOD PRESSURE QUANTITATIVE TRAIT LOCUS ON RATCHROMOSOME 1 AND GENE EXPRESSION ANALYSIS IDENTIFIES SPON1 AS ANOVEL CANDIDATE HYPERTENSION GENE

Bingham, AJ1; Clemitson, J1; Dixon, RJ1; Haines, S1; Patel, B1; Hall, L1; Lo, M2; Sassard, J2; Charchar, FJ1; Samani, NJ1

1. University of Leicester, Leicester, United Kingdom; 2. Faculte de Pharmacie, Lyon, France

008

INTERLEUKIN 1 (IL1) IS SIGNIFICANTLY ASSOCIATED WITH CAD IN A LARGE UKDISCORDANT SIBSHIP COLLECTION

Brown, BD1; Balmforth, AJ2; Nsengimana, J3; Barrret, J3; Lawrence, RA1; Hall, AS2

1. Leeds General Infirmary, Leeds, United Kingdom; 2. Institute for Cardiovascular Research, Leeds, United Kingdom; 3. Cancer Research, Leeds, United Kingdom

Exhibition break 10.00-11.30Moderated Posters

Clinical science

Chair: Prof Michael Marber and Dr Peter Schofield

009

THE STENT OR SURGERY LONG TERM FOLLOW UP

Stables, RH1; Booth, J2; Pepper, J2; Clayton, T3; Flather, M2; Nugara, F2; Sigwart, U4

1. Liverpool Cardiothoracic Centre, Liverpool, United Kingdom; 2. Royal Brompton & Harefield NHS Trust,London, United Kingdom; 3. London School of Hygiene & Tropical Medicine, London, United Kingdom; 4. University Hospital, Geneva, Switzerland

25


Programme

24

Alsh 08.30-10.00British Society for Cardiovascular Research (BSCR)

Molecular and clinical aspects of vascular calcification: prognostic and therapeutic implications

Chair: Dr Yvonne Alexander and Prof Peter Weissberg

Imaging vascular calcification: prognostic and therapeutic implicationsProf Paolo Raggi

Boning up on rat arteries: detection, quantification and intervention in experimentalvascular calcificationDr Veerle Persy

Molecular and cellular studies of cardiac valve calcificationDr Adrian Chester

Factors involved in the pathogenesis of arterial calcification in diabetesDr William Jeffcoate


Basic science

Chair: Prof Nilesh Samani and Prof Bernard Keavney

003

ASSOCIATION BETWEEN THE PURINERGIC RECEPTORS P2X4, P2X6 AND P2X7GENETIC VARIATION AND BLOOD PRESSURE IN A BRITISH POPULATION

Palomino Doza, Julian1; Keavney, B1; Rahman, T2; Eden, J3; Hussain, R1

1. Institute of Human Genetics, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom; 2. Institute of Human Genetics, University of Newcastle upon Tyne, United Kingdom; 3. Instute of HumanGenetics, Newcastle upon Tyne, United Kingdom

004

INTEGRATED GENETIC LINKAGE ANALYSIS AND EXPRESSION PROFILING IN THERAT HEART TO IDENTIFY PRIMARY DRIVERS OF CARDIAC HYPERTROPHY

Sarwar, R1; Petretto, E1; Lu, H1; Kumaran, MK1; Schroen, B2; Fischer, J3; Hubner, N3; Mangion, J1; Pinto, YM2; Pravenec, M4; Aitman, TJ1; Cook, SA1

1. MRC-CSC Imperial College, London, United Kingdom; 2. CARIM Maastricht University, Maastricht, Netherlands; 3. Max Delbrück Center, Berlin, Germany; 4. Czech Academy of Sciences, Prague, Czech Republic

CP

D d

ayTu

esda

y 5

June

27

014

ARE THERE ETHNIC DIFFERENCES IN THE DIAGNOSTIC AND PROGNOSTIC VALUE OF ANGINA SYMPTOM DESCRIPTORS? A 3-YEAR PROSPECTIVE STUDY OF 2189 SOUTH ASIANS

Zaman, MJS1; Junghans, C1; Sekhri, N2; Feder, G3; Timmis, A3; Hemingway, H1

1. University College London, London, United Kingdom; 2. Newham University Hospital, London, United Kingdom; 3. Queen Mary’s School of Medicine and Dentistry, London, United Kingdom

Clyde 11.30-13.00British Atherosclerosis Society (BAS)British Society for Cardiovascular Research (BSCR)British Cardiovascular Intervention Society (BCIS)

Endothelial dysfunction and thrombosis following stenting: scientific and clinical issues

Chair: Prof Keith Channon and Prof Roger Wadsworth

Endothelial repopulation after injury: role of EPCsDr Jonathan Hill

Platelet and inflammatory cell interactionsProf Christian Weber

Thrombosis risk after stenting: where do we stand?Dr Keith Oldroyd

Endothelial cell repopulation after PCI: clinical implicationsDr Robbert De Winter

Lomond 11.30-13.00Primary Care Cardiovascular Society (PCCS)British Hypertension Society (BHS)

Challenges in hypertension

Chair: Prof Gordon McInnes

Challenges of reaching targets in hypertension Dr Terry McCormack


Debate: This house believes beta blockers should be restored as first line in hypertension

Chair: Prof Morris Brown

For: Prof Gordon McInnes

Against: Dr Gareth Beevers



Programme

26

010

EFFECT OF INCOMPLETE REVASCULARISATION ON OUTCOME FOLLOWINGPERCUTANEOUS CORONARY INTERVENTION FOR MULTI-VESSEL DISEASE:SCOTTISH CORONARY REVASCULARIATION REGISTER

Pell, JP1; Oldroyd, K2; Slack , R3; Pell, ACH4; Eteiba, H5; Flapan, A6; Hillis, S2; Irving, J7; Jennings, K8; Northcote, R9; Starkey, I6

1. BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom; 2. Western Infirmary, Glasgow, United Kingdom; 3. Greater Glasgow NHS Board, Glasgow, United Kingdom; 4. Monklands Hospital, Airdrie, United Kingdom; 5. Glasgow Royal Infirmary, Glasgow, United Kingdom; 6. Royal Infirmary, Edinburgh, United Kingdom; 7. Ninewells Hospital, Dundee, United Kingdom; 8. Aberdeen Royal Infirmary, Aberdeen, United Kingdom; 9. Victoria Infirmary, Glasgow, United Kingdom

011

REMOTE ISCHAEMIC PRECONDITIONING PROTECTS THE HEART AT TIME OF CABGSURGERY

Mwamure, PK1; Hausenloy, DJ1; Harris, J1; Barnard, M2; Grundy, E2; Ashley, E2; Di Salvo, C2; Vichare, S2; Kolvekar, S2; Hayward, M2; Keogh, B2; MacAllister, RJ3; Yellon, DM1

1. The Hatter Cardiovascular Institute, UCL., London, United Kingdom; 2. The UCLH Heart Hospital, London,United Kingdom; 3. Centre for Clinical Pharmacology and Therapeutics, UCL, London, United Kingdom

012

STRESS ECHOCARDIOGRAPHY CAN SAFELY, RAPIDLY AND ACCURATELY RISKSTRATIFY PATIENTS WITH SUSPECTED ACUTE CORONARY SYNDROME AND ANINITIAL (12 HOUR) NEGATIVE TROPONIN: IMPLICATIONS FOR EARLY USE OF STRESSECHOCARDIOGRAPHY IN THE EMERGENCY DEPARTMENT

Jeetley, P; Burden, L; Senior, R

Northwick Park Hospital, Harrow, United Kingdom

013

ISCHAEMIC AND THROMBOTIC EFFECTS OF DILUTE DIESEL EXHAUST INHALATIONIN PATIENTS WITH CORONARY HEART DISEASE: MECHANISMS FOR THE ADVERSECARDIOVASCULAR EFFECTS OF AIR POLLUTION

Mills, NL1; Törnqvist, H2; Gonzalez, MC2; Vink, E3; Robinson, SD4; Söderberg, S2; Donaldson, K5; Sandström, T6; Blomberg, A6; Boon, NA3; Newby, DE3

1. Edinburgh Royal Infirmary, Edinburgh, United Kingdom; 2. Umeå University, Umeå, Sweden; 3. Royal Infirmary Edinburgh, Edinburgh, United Kingdom; 4. James Cook University Hospital, Middlesbrough, United Kingdom; 5. The University of Edinburgh, Edinburgh, United Kingdom; 6. Umeå University, Umeå, United Kingdom

CP

D d

ayTu

esda

y 5

June

29

Alsh 11.30-13.00British Association for Cardiac Rehabilitation (BACR)

Promoting physical activity in the sedentary cardiac patient

Chair: Mrs Bernie Downey

A study evaluating physical activity outcome measures in cardiac rehabilitationpatients: accelerometers versus questionnairesDr A Orrell

Seated exercise in heart failure: METs and strength demandProf Patrick Doherty

Update from the NACR data base: physical activity dataProf Robert Lewin

Exhibition break 13.00-14.30

Lomond 13.15-14.15Sponsored symposiumSponsored by Servier

Heart rate: is our finger on the pulse?

Chair: Prof Philip Poole-Wilson

Established cardiovascular risk factors: from discovery to treatmentProf Mark Kearney

Heart rate: the forgotten cardiovascular risk factor?Prof John Camm

Lowering heart rate in clinical practiceProf Kim Fox

Hall 1 13.15-14.15Sponsored symposiumSponsored by Novartis

Winning the battle with difficult and resistant hypertension

Chair: Prof Neil Poulter

Difficult and resistant hypertension: minimising the risk Prof Neil Poulter

Interactive case discussion: refractory hypertension in a patient on triple therapy –where to next? Prof Morris Brown

Side effects in combination treatment: considerations for management Dr Adrian Brady



Programme

28

Hall 1 11.30-13.00British Society for Heart Failure (BSH)Heart Rhythm UK (HRUK)

Atrial fibrillation in heart failure

Chair: Dr Clifford Garratt and Dr Suzanna Hardman

Panel: Prof John CammProf Martin CowieDr Theresa McDonaghDr Richard SchillingDr Jay Wright

AF in heart failure – cause or effect – scale of the problem Prof Martin Cowie

Drug therapy for AF in the heart failure patient Prof John Camm

The role of CRT in the patient with AF Dr Jay Wright

The role of left atrial ablation in the heart failure patient Dr Richard Schilling

Forth 11.30-13.00British Society of Echocardiography (BSE)

New techniques in the echo lab?

Chair: Dr Harald Becher and Dr Richard Jones

Tissue DopplerDr John Sanderson

ContrastDr Roxy Senior

3D echoDr Mark Monaghan


CP

D d

ayTu

esda

y 5

June

31

Lomond 14.30-16.00British Cardiovascular Society (BCS)American College of Cardiology (ACC)

Avoiding complications with cardiovascular drugs

Chair: Dr Nicholas Boon and Dr Douglas Weaver

Recommendations for first-in-man clinical trials following the TGN1412 trial in March 2006Prof Sir Gordon Duff

Proarrythmia and drugs Prof John Camm

Role of peer review and editorial responsibility in pharmaceutical investigational studiesMs Fiona Godlee

Adverse cardiovascular reactions to non-steroidal anti-inflammatory drugsDr Douglas Weaver

Hall 1 14.30-16.00British Society of Echocardiography (BSE)

Multimodality monitoring of valve disease

Chair: Prof Roger Hall

Echo is all you needDr John Chambers

BNP adds to the pictureDr Kevin Fox

Is there still a role for the history?Dr Bernard Prendergast

(Cardio-pulmonary) exercise testing is valuableDr Andrew Clark

Putting it all together into an integrated valve monitoring serviceDr Guy Lloyd


Programme

30

Forth 13.15-14.15How to advise the patient with congenital heart disease and their family

Chair: Dr Anthony Salomon and Mrs Sheena Vernon

The cliniciansDr Frank Casey

A psychologist’s insight – the CHIP studyDr Nicola Doherty


Alsh 13.15-14.15How to follow up the patient with a prosthetic valve

Chair: Mr Graham Cooper and Mr Bernard Prendergast

Prosthetic valves: old vs new, tissue vs mechanicalMr Robert Jeffrey

Echocardiographic features of prosthetic valves: normal and abnormalDr Adrian Ionescu

Clinical follow up and management of complicationsDr John Chambers

Boisdale 13.15-14.15How to set up a primary angioplasty service

Chair: Dr Farzim Ordoubadi

Starting from scratchMr Roger Gamon

Sustaining a 24/7 serviceDr Jim McLenachan

Interaction with secondary careDr Alan Fitchet

Carron 13.15-14.15How to select patients for cardiac resynchronisation therapy

Chair: Dr Vince Paul

Clinical criteriaProf John Cleland

Echocardiographic criteriaDr Mark Monaghan

CP

D d

ayTu

esda

y 5

June

33

Lomond 18.30-20.00Sponsored symposiumSponsored by Daiichi-Sankyo/Lilly

Optimal antiplatelet treatment of ACS patients undergoing PCI

Chair: Dr Mark de Belder and Dr Adrian Banning

Acute versus chronic antiplatelet needs for ACS-PCI: fast, potent and reliableDr Rod Stables

Monitoring and clinical significance of variable antiplatelet response in ACSDr Nick Curzen

Future challenges in antiplatelet therapy for ACS-PCIDr Rob Storey


Forth 18.30-20.00Sponsored symposiumSponsored by sanofi-aventis

Cardiovascular disease, abdominal obesity and the endocannabinoid system

Chair: Prof Derek Yellon and Dr Huon Gray

Where are we now and where are we going?Prof Derek Yellon and Dr Huon Gray

Why should we be managing residual risk?Dr Henry Purcell

Treatment of obesity and associated risk factors by CB1 blockadeProf Rafael Maldonado

The journey from RIO to SwanseaDr Clive Weston



Programme

32

Forth 14.30-16.00Heart Rhythm UK (HRUK)Primary Care Cardiovascular Society (PCCS)

Atrial fibrillation in primary care

Chair: Dr Derek Connelly, Dr Ahmet Fuat and Prof Richard Hobbs

Atrial fibrillation: the scale of the problemProf John McMurray

Who needs aspirin, who needs warfarinProf David Fitzmaurice

Which patients to refer for specialist managementDr Edward Rowland


Alsh 14.30-16.00British Society for Heart Failure (BSH)British Congenital Cardiac Association (BCCA)

The right stuff

Chair: Dr Suzanna Hardman and Dr Graham Stuart

Pathophysiology of right ventricular failureProf Michael Frennaux

Differential diagnosis and investigation of right ventricular failureDr Andrew Clark

Optimal management in patients with congenital heart diseaseProf Andrew Reddington

Optimal management in patients without CHDProf John McMurray


Lomond 17.00-18.00Paul Wood LectureProf Catherine Otto

Aortic valve stenosis: changing concepts of disease and management

Introduced by Dr Nicholas Boon; Thanked by Prof Roger Hall

CP

D d

ayTu

esda

y 5

June

3534

BCISWorkshop

DebateProphylactic antibiotic

therapy to preventendocarditis after dental

procedures is unnecessaryand inappropriate

Sponsored symposiumPfizer

Debate Cholesterol targets of 4 and2mmol/L should be national policy for patients with established CHD

BCS/ESCAcute coronary

syndromes

BCS/RCP Lecturesupported by the Joy

Edelman Legacy Prof John Cleland

British CardiovascularSociety

AGM(members only)

BSEWorkshop

BSCMR/BSHWorkshop

HRUKWorkshop

SCSTRegistrationand AGM

SCSTCardiac

physiologistsand ACHDSession 1

SCSTCardiac

physiologistsand ACHDSession 2

BCSThe workplace

and cardiovascularhealth

BSH/BSE/BSCRCytotoxic

chemotherapyand the heart

8.30

10.00

11.00

12.3012.45

14.00

15.30

16.00

17.00

18.3020.00

BANCCNurse led angiography


BANCCAbstracts(64-69)

BANCCInequalities and cardiovascular

diseaseBANCC/HCP(UK)/BHF/BACRWorking together for women’s

cardiovascular health

B C S A n n u a l D i n n e r a t t h e K e l v i n g r o v e A r t G a l l e r y ( t i c k e t s o n l y )

Clyde Lomond Hall 1 Forth Alsh

Exhibition break

M o d e r a t e d p o s t e r s i n e x h i b i t i o n ( 5 2 - 6 3 )

Sponsored symposiumSchering Plough/MSD

Balance: the art of cholesterol management

Young ResearchWorkers’ Prize

Exhibition break

Audit, guidelines and epidemiology

(15-21)


(70-78)


(115-123)

EP Intervention and ablation

(22-28)


(79-87)

Interventionalcardiology(124-130)

S of A

Myocardial biology (29-37)

Paediatric, adultcongenital heart

disease and valvedisease(88-96)

Echocardiography(131-139)

Heart failure and cardiac transplant

(38-44)

Heart Failure andcardiac

transplantation(97-105)

EP Intervention and ablation

(140-148)

Nuclear, MRI and CT(45-51)

Medical treatment of coronary artery disease and acute

coronary syndromes (not intervention)

(106-114)

Nuclear, MRI and CT

(149-157)

B C S A n n u a l D i n n e r a t t h e K e l v i n g r o v e A r t G a l l e r y ( t i c k e t s o n l y )

Boisdale Carron Dochart Gala Leven

M o d e r a t e d p o s t e r s i n e x h i b i t i o n( 5 2 - 6 3 )

How to find new genesfor cardiovascular

disease (and why it isimportant)

How to select casesfor percutaneous closureof the inter-atrial septum

How to manage the survivors of out-of-hospital cardiac arrest

How to improve yourpresentation skills

Exhibition break


CPD and research day Wednesday 6 June

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


37

Hall 1 08.30-10.00British Society of Echocardiograhy (BSE)

Workshop

Interactive teaching cases in echocardiography

Chair: Dr Timothy Bloomer and Dr Jamil Mayet

Teaching cases in echocardiology

Case 1Dr Nav Masani

Case 2Dr Bushra Rana

Case 3Dr Antoinette Kenny

Case 4Dr Simon Ray

Forth 08.30-10.00Society for Cardiological Science and Technology (SCST)

Registration and AGM

Alsh 08.30-10.00British Cardiovascular Society (BCS)

The workplace and cardiovascular health

Chair: Prof Dame Carol Black and Dr Howard Swanton

Health, work and well-beingProf Dame Carol Black

Men’s health in the workplaceProf Ian Banks

The methodology behind developing regulations for drivers with cardiovascular disordersDr Michael Petch

The interface between the workplace and cardiovascular health especially with regard to returning to work after heart diseaseDr Anne Price

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

36


Clyde 08.30-10.00British Association for Nursing in Cardiac Care (BANCC)

Nurse led angiography

Welcome: Mr Ian Jones and Ms Maree Barnett

Debate: Non-medical versus medical angiography – fad or future?

Chair: Mr Alun Roebuck and Prof David Thompson

For: Ms Vanessa BeattieDr John Caplin

Against: Ms Sharon BarnesDr Aswar Zamen

Lomond 08.30-10.00British Cardiovascular Intervention Society (BCIS)

Workshop

Multidisciplinary decision making in inerventional cardiology

Chair: Dr Simon Redwood

Panel: Dr Andreas BaumbachDr Joe McGoldrickDr Bernard PrendergastDr Nicholas West

Data presentation

Dr Robert Henderson

Revascularisation prior to non-cardiac surgeryDr Philip MacCarthy

Revascularisation and ICD during ischaemic ventricular arrhythmiasDr Mark Gunning

Choice of DES vs BMS in patients “committed” to warfarin therapyDr Akhil Kapur

Decision making after DES SASTDr Nicholas Bellenger

39

019

EUROACTION: A EUROPEAN SOCIETY OF CARDIOLOGY DEMONSTRATION PROJECTIN PREVENTIVE CARDIOLOGY – ONE YEAR RESULTS FOR CORONARY PATIENTS ANDTHEIR PARTNERS

Connolly, SB1; Kotseva, K2; Jennings, C2; Mead, A2; Jones, J2; Holden, A2; De Backer, G3; DeBacquer, D3; Collier, TA4; Wood, DA2

1. Imperial college, London, United Kingdom; 2. Imperial College, London, United Kingdom; 3. University of Ghent, Ghent, Belgium; 4. London School of Hygiene and Tropical Medicine, London, United Kingdom

020

ATRIAL FIBRILLATION IN A PRIMARY CARE POPULATION: HOW CLOSE TO NICEGUIDELINES ARE WE?

Loo, B1; Parnell, C1; Brook, G2; Southall, E3; Mahy, I1

1. Torbay General Hospital, Torquay, United Kingdom; 2. Barton Sugery, Dawlish, United Kingdom; 3. Mayfield Surgery, Torquay, United Kingdom

021

ETHNIC DIFFERENCES IN RATES OF MYOCARDIAL INFARCTION IN PATIENTS WITHHYPERTENSION ARE EXPLAINED BY AN EXCESS OF DIABETES

Lim, HS1; Patel, JV1; Lip , GYH1; Tracey, I2; Gunarathne, A3; Hughes, EA3

1. City Hospital, Birmingham, United Kingdom; 2. Sandwell medical Research Unit, West Bromwich, United Kingdom; 3. Sandwell Medical Research Unit, West Bromwich, United Kingdom

Carron 08.30-10.00Abstracts

EP intervention and ablation

Chair: Dr Nicholas Linker and Dr Richard Shilling

State of the art: Current status of ablation therapy for AFDr David Connolly

022

SINGLE CENTRE UK EXPERIENCE OF CRYOABLATION BALLOON FOR PAROXYSMAL AF

Sandilands, AJ; Woodburn, K; Boreham, PA; Cripps, TR

Bristol Royal Infirmary, Bristol, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

38

Boisdale 08.30-10.00Abstracts


Chair: Dr Andrew Bishop and Prof Stuart Cobbe

State of the art: Effecting change in clinical practiceProf David Wood

015

IMPLICATIONS OF GUIDELINES FOR STATIN TREATMENT FOR SECONDARYPREVENTION OF CARDIOVASCULAR DISEASE – RISK FACTOR ANALYSIS OF THESCOTTISH HEALTH SURVEY 2003

Haq, I1; Hill, J2; Craig, J3; Ritchie, L4

1. Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; 2. Quality Improvement Scotland,Edinburgh, United Kingdom; 3. Quality Improvement Scotland, Glasgow, United Kingdom; 4. Unversity ofAberdeen, Aberdeen, United Kingdom

016

AGEING DIMINISHES THE PUMPING CAPACITY OF HEALTHY HUMAN MALE BUT NOTFEMALE HEARTS

Lewis, NT1; Goldspink, DF2; Clements, RE2; Sharp, L2; Chantler, PD2; Patwala, A3; George, K2; Stephenson, C2; Tan, LB1

1. Leeds General Infirmary, Leeds, United Kingdom; 2. Research Institute for Sports & Exercise Sciences,Liverpool John Moores University, Liverpool, United Kingdom; 3. The Cardiothoracic Centre in Liverpool,Liverpool, United Kingdom

017

DIFFERENCES BETWEEN THE EUROPEAN AND AMERICAN SOCIETY GUIDELINESINFLUENCE THE NUMBER AND DURATION OF CHEST PAIN ADMISSIONS

Good, RIS; Pollock, M; Carrick, A; Murphy, A; Oldroyd, KG; Robb, SD

Western Infirmary, Glasgow, United Kingdom

018

MANUAL ASSESSMENT OF QRS DURATION: IMPORTANCE OF ECG FORMAT ANDCLINICAL IMPLICATIONS IN LIGHT OF NICE ICD IMPLANTATION GUIDELINES

Tomlinson, DR; Timperley, J; Ehtisham, J; Sabharwal, N; Myerson, S; Ryding, A; Shirodaria, C; Bashir, Y; Betts, TR

Department of Cardiology, John Radcliffe Hospital, Oxford, United Kingdom

41

028

THE IMPACT OF IMAGE INTEGRATION ON CATHETER ABLATION OF ATRIAL FIBRILLATION USING ELECTROANATOMIC MAPPING: A PROSPECTIVE RANDOMISED STUDY

Kistler, P1; Rajappan, K1; Harris, S1; Gupta, D1; Richmond, L1; Ellis, S2; Sporton, SC1; Schilling, RJ1

1. The Department of Cardiology, St Bartholomew’s Hospital and Queen Mary University, London, United Kingdom; 2. The Department of Radiology, St Bartholomew’s Hospital and Queen Mary University,London, United Kingdom

Dochart 08.30-10.00Abstracts

Myocardial biology

Chair: Prof Metin Avkiran and Prof Ludwig Neyses

029

EFFICIENT CARDIAC GENE DELIVERY TO RAT HEART BY INTRAVASCULARINJECTION OF ADENO-ASSOCIATED VIRUS-6

Masson, R1; Work, LM1; Nicklin, SA1; Gregorevic, P2; Allen, JM2; Chamberlain, JS2; Baker, AH1

1. BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom; 2. Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Centre, University of Washington,Seattle, United States

030

THE ADIPOCYTOKINE, VISFATIN, REDUCES MYOCARDIAL INFARCT SIZE, WHENGIVEN AT AT TIME OF REPERFUSION, BY INHIBITING THE MITOCHONDRIALPERMEABILITY TRANSITION PORE

Hausenloy, DJ; Shiang-Yong, L; Paramanathan, AJ; Davidson, S; Smith, CCT; Yellon, DM

The Hatter Cardiovascular Institute, UCL., London, United Kingdom

031

METFORMIN GIVEN AT TIME OF REPERFUSION REDUCES MYOCARDIAL INFARCT SIZE THROUGH THE AKT-MEDIATED INHIBITION OF MITOCHONDRIALPERMEABILITY TRANSITION PORE OPENING

Hausenloy, DJ; Bhamra, GS; Davidson, S; Carr, R; Mocanu, M; Yellon, DM


CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

40

023

THROMBOEMBOLISM RISK REDUCTION IN PATIENTS UNDERGOING CATHETERABLATION PROCEDURES FOR PERSISTENT AND PAROXYSMAL ATRIALFIBRILLATION: A COMPARISON OF UK AND INTERNATIONAL PROTOCOLS

Tomlinson, DR; Betts, TR; Bashir, Y

Department of Cardiology, John Radcliffe Hospital, Oxford, United Kingdom

024

A STUDY TO IDENTIFY THE PREVALENCE AND TIMING OF PERICARDIAL EFFUSIONSAFTER LEFT ATRIAL CATHETER ABLATION FOR ATRIAL FIBRILLATION AND ATRIALTACHYCARDIA

Kalla, M; Rajappan, K; Kalra, S; Sporton, SC; Schilling, RJ

The Department of Cardiology, St Bartholomew’s Hospital and Queen Mary University, London, United Kingdom

025

THE IMPACT OF LINEAR ABLATION ALONG THE CORONARY SINUS ON THEOUTCOMES OF CATHETER ABLATION FOR PERMANENT ATRIAL FIBRILLATION

Rajappan, K; Kalra, S; Kalla, M; Earley, M; Harris, S; Gupta, D; Abrams, D; Sporton, SC; Schilling, RJ

The Department of Cardiology, St Bartholomew’s Hospital and Queen Mary University, London, United Kingdom

026

CATHETER ABLATION FOR PERMANENT ATRIAL FIBRILLATION: ARE OUTCOMESIMPROVED BY ABLATION RESTORING SINUS RHYTHM WITHOUT ELECTRICALCARDIOVERSION?

Rajappan, K; Kistler, P; Kalla, M; Kalra, S; Richmond, L; Earley, MJ; Harris, S; Gupta, D; Abrams, D; Sporton, SC; Schilling, RJ

The Department of Cardiology, St Bartholomew’s Hospital and Queen Mary University, London, UnitedKingdom

027

SIMPLE DOSE LIMITATION MANOEUVRES CAN SIGNIFICANTLY REDUCE RADIATIONEXPOSURE DOSE DURING RADIOFREQUENCY ABLATION

Rogers, DP; England, F; Ahmed, A; Dhinoja, M; Lowe, MD; Lambiase, PD; Chow, AW

The Heart Hospital, London, United Kingdom

43

037

PRECONDITIONING AND POSTCONDITIONING: THE MITOCHONDRIAL PERMEABLITYTRANSITION PORE AS THE COMMON END-EFFECTOR

Shiang-Yong, L; Hausenloy, DJ; Davidson, S; Yellon, DM


Gala 08.30-10.00Abstracts

Heart failure and cardiac transplantation

Chair: Dr Peter Cowburn and Dr Alan Struthers

State of the art: Biomarkers in heart failureProf Martin Cowie

038

C-TERMINAL Pro-ENDOTHELIN-1 OFFERS ADDITIONAL PROGNOSTIC INFORMATION WITH NTproBNP IN PATIENTS FOLLOWING ACUTE MYOCARDIALINFARCTION. THE LEICESTER ACUTE MYOCARDIAL INFARCTION PEPTIDE (LAMP) STUDY

Khan, SQ1; Dhillon, O1; Struck, J2; Quinn, P1; Morgenthaler, N2; Squire, I3; Davies, J1; Bergmann, A2; Ng, LL1

1. University of Leicester, Leicester, United Kingdom; 2. Brahms AG, Hennigsdorf/Berlin, Germany; 3. University of Leicester, Leicester, Germany

039

PLASMA MMP-9 AND TIMP-1: NOVEL MARKERS OF LV DYSFUNCTION AND ADVERSEPROGNOSIS AFTER ACUTE MYOCARDIAL INFARCTION IN MAN

Kelly, D1; Thompson, M2; Samani, NJ1; Khan, SQ1; Cockerill, G2; Ng, LL1; Squire, IB1

1. University Hospitals Leicester, Leicester, United Kingdom; 2. St George’s Hospital Medical School, London, United Kingdom

040

THE CRITICAL ROLE OF ERBB2 IN HUMAN LEFT VENTRICULAR REMODELLING DUE TO PRESSURE OR VOLUME OVERLOAD

Jin, XY1; Hu, JT2; Pezzella, F2; Pepper, JR3

1. John Radcliffe Hospital, Oxford, United Kingdom; 2. NDCLS, Oxford University, Oxford, United Kingdom; 3. Royal Brompton Hospital, London, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

42

032

DIFFERENTIAL ROLE OF NNOS IN HEART RATE REGULATION BETWEEN REST AND EXERCISE

Adlam, D1; de Bono, JP1; Casadei, B1; Paterson, DP2; Channon, KM1

1. Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom; 2. Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

033

IS INCREASED MYOCARDIAL OXIDATIVE STRESS AN EARLY EVENT IN THE NATURALHISTORY OF ATRIAL FIBRILLATION (AF)?

Reilly, Svetlana1; Idigo, Winifred1; Zhang, Mei2; Hale, Ashley2; Schotten, Uli3; Alp, Nicholas1; Casadei, Barbara1

1. University of Oxford, Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, United Kingdom; 2. Department of Cardiovascular Medicine, Wellcome Trust Centre of Human Genetics,Oxford, United Kingdom; 3. Department of Physiology, Cardiovascular Research Institute Maastricht,Maastricht University, Maastricht, Netherlands

034

CARDIAC AND SYSTEMS BIOLOGY OF ISOFORM 4 OF THE PLASMA MEMBRANECALCIUM ATPASE

Cartwright, EJ; Baudoin, F; Oceandy, D; Prehar, S; Zi, M; Neyses, L

University of Manchester, Manchester, United Kingdom

035

PLASMA MEMBRANE CALCIUM ATPASE PUMP ISOFORMS 1 AND 4 DIFFERENTIALLYREGULATE HEART CONTRACTILITY

Mohamed, T; Oceandy, D; Alatwi, N; Baudoin, F; Cartwright, E; Neyses, L


036

GLIMEPIRIDE TREATMENT FACILITATES THE PROTECTIVE EFFECT OF ISCHAEMICPRECONDITIONING IN THE DIABETIC HEART

Hausenloy, DJ; Wynne, A; Mocanu, M; Yellon, DM


45

Leven 08.30-10.00Abstracts

Nuclear, MRI and CT

Chair: Dr David Dutka and Dr Richard Steeds

State of the art: New imaging for ischaemic heart diseaseDr Charles Peebles

045

CARDIOVASCULAR MAGNETIC RESONANCE PERFUSION IMAGING AT 3 TESLA FORTHE DETECTION OF CORONARY ARTERY DISEASE: A COMPARISON WITH 1.5 TESLA

Cheng, ASH1; Pegg, TJ1; Karamitsos, TD1; Robson, MD1; Searle, N1; Jerosch-Herold, M2; Choudhury, RP3; Banning, AP3; Selvanayagam, JB3

1. John Radcliffe Hospital/Department of Cardiovascular Medicine, Oxford, United Kingdom; 2. Advanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon, United States; 3. John Radcliffe Hospital/Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom

046

CAN FALSE POSITIVE AND NEGATIVE FIRST PASS MYOCARDIAL PERFUSION MRISCANS BE EXPLAINED BY CORONARY PHYSIOLOGICAL MEASUREMENTS?

Watkins, S1; Steedman, T1; Lyne, J2; Foster, J1; Ford, I3; Dargie, HJ1; Oldroyd, KG1

1. Western Infirmary, Glasgow, United Kingdom; 2. Royal Brompton Hospital, London, United Kingdom; 3. University of Glasgow, Glasgow, United Kingdom

047

ISCAHEMIA AND SCAR BURDEN AFTER ACUTE MYOCARDIAL INFARCTION

Plein, S; Younger, J; Sparrow, P; Ridgway, J; Sivananthan, M; Ball, S; Greenwood, J

University of Leeds, Leeds, United Kingdom

048

31P CARDIAC MAGNETIC RESONANCE SPECTROSCOPY DURING PHYSIOLOGICALLEG EXERCISE AT 3 TESLA

Hudsmith, LE1; Tyler, DJ1; Emmanuel, Y1; Francis, JM1; Petersen, SE1; Clarke, K2; Watkins, H1; Robson, MD1; Neubauer, S1

1. Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom; 2. Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

44

041

THE EFFECT OF INTRODUCING DIURETICS IN COMPENSATED PATIENTS WITH LEFTVENTRICULAR DYSFUNCTION ON QUALITY OF LIFE, PLASMA BNP LEVELS, NBNPLEVELS AND PEAK OXYGEN CONSUMPTION: RESULTS FROM A DOUBLE BLINDPLACEBO CONTROLLED CROSS-OVER STUDY

Gupta, S1; Gandhi, N1; Waywell, C1; Clayton, N1; Coppinger, T1; Ng, LL2; Brooks, NH1; Neyses, L3

1. Wythenshawe Hospital, Manchester, United Kingdom; 2. Leicester Royal Infirmary, Leicester, United Kingdom; 3. University of Manchester, Manchester, United Kingdom

042

IS DIASTOLIC HEART FAILURE A MYTH?

Townsend, M1; MacIver, DH2

1. Bristol royal infirmary, North Somerset, United Kingdom; 2. Taunton and Somerset NHS Trust, Taunton, United Kingdom

043

PREVALENCE OF HEART FAILURE PRESERVED EJECTION FRACTION IN THE COMMUNITY

Mahadevan, G; Williams, LK; Campbell, RI; Palin, T; Weaver, R; Marsh, A; Hobbs, FDR; Frenneaux, MP

University of Birmingham, Birmingham, United Kingdom

044

CARDIORESPIRATORY CONTROL INSTABILITY IN HEART FAILURE – DOES THECHEMOREFLEX SHOW ADAPTATION OR ARE WE MISSING THE POINT?

Manisty, CH1; Jaisval, S2; Davies, JE1; Hadjiloizou, N1; Hughes, AD1; Mayet, J1; Willson, K1; Francis, DP1

1. International Centre for Circulatory Health, Imperial College and St. Mary’s Hospital, London, United Kingdom; 2. Imperial College, London, United Kingdom

47

054

NF-κB INHIBITION BY BLOCKADE OF IKK-2 AND MYD88 IN VEIN GRAFT SMOOTH MUSCLE CELLS REDUCES THE EXPRESSION OF KEY MEDIATORS OF INTIMAL HYPERPLASIA

Finch, JR1; Navin, T2; Gregan, SM2; Foxwell, B3; Haskard, DO1; Monaco, C2; Hornick, PI4

1. NHLI, Imperial College London, London, United Kingdom; 2. Cytokine Biology of Vessels, Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom; 3. Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom; 4. Department of CardiothoracicSurgery, Hammersmith Hospital., London, United Kingdom

055

HYPERGLYCAEMIA REDUCES ENDOTHELIAL PROGENITOR CELL ADHERENCE AND DIFFERENTIATION IN VITRO

Moore, JS; Whittaker, A; Vasa, M; Samani, NJ

Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom

056

DISCORDANT RESPONSE TO EXERCISE TRAINING IN NNOS KNOCKOUT MICE:DIFFERENTIAL ROLE OF NNOS ON EXERCISE PERFORMANCE VERSUS CARDIAC HYPERTROPHY

de Bono, JP1; Adlam, D1; Zhang, MH1; Paterson, DP2; Casadei, B1; Channon, KM1


057

WHITE BLOOD CELL TELOMERE LENGTH IS ASSOCIATED WITH LEFT VENTRICULARFUNCTION IN THE OLDEST OLD: THE NEWCASTLE 85+ STUDY

Collerton, JC1; Martin-Ruiz, CM1; Kenny, MA2; Barrass, K1; von Zglinicki, T1; Kirkwood, TBL1; Keavney, B1

1.Newcastle University, Newcastle upon Tyne, United Kingdom; 2.Freeman Hospital, Newcastle upon Tyne, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

46

049

NEGATIVE MULTI-DETECTOR CORONARY CTA IN SYMPTOMATIC PATIENTSCONFERS A GOOD ONE YEAR PROGNOSIS

van Lingen, R; Manghat, N; Kakani, N; Roobottom, C; Morgan-Hughes, G

Derriford Hospital, Plymouth, United Kingdom

050

LONG-TERM CORONARY ARTERY BYPASS GRAFT PATENCY AS ASSESSED BY MULTISLICE COMPUTED TOMOGRAPHY, QUALITY OF LIFE AND ADVERSEEVENTS IN PATIENTS RANDOMISED TO ON AND OFF-PUMP SURGERY

Smith, DK1; Murphy, G2; Reeves, BC3; Culliford, L3; Rogers, C3; Coles, DR4; Baumbach, A3; Angelini, GD3

1. Gloucestershire Royal Hospital NHS Trust, Gloucester, United Kingdom; 2. Bristol Royal Infirmary, Bristol, United Kingdom; 3. Bristol Heart Institute, Bristol, United Kingdom; 4Barnstaple Hospital, Barnstaple, United Kingdom

051

THE 2 YEAR FOLLOW UP OF 410 PATIENTS PRESENTING TO A DISTRICT GENERALHOSPITAL WITH CHEST PAIN AND A CT CORONARY CALCIUM SCORE OF ZERO

Keeble, TR1; Hague, A1; Powles, S1; Thain, A1; Smith, EJ2; Prasad, R1; Mazhar, S1; Nageh, T1; Kelly, P1; Khokhar, A1

1. Southend Hospital, Southend, United Kingdom; 2. London Chest Hospital, Bethnal Green, United Kingdom


Basic Science

Chair: Prof Barbara Casadei and Prof Ajay Shah

052

A POTENTIAL ROLE FOR OSTEOPROTEGERIN IN IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION.

Lawrie, Allan1; Suntharalingham, J2; Southwood, M2; Francis, SE1; Crossman, DC1; Morrell, NW2; Newman, CM1

1. University of Sheffield, Sheffield, United Kingdom; 2. University of Cambridge, Cambridge, United Kingdom

053

THE NOVEL PEPTIDE, APELIN, IS A VASODILATOR IN VIVO IN MAN

Japp, AG1; Li, VKY1; Cruden, NL2; Flapan, AD3; Newby, DE1

1. University of Edinburgh, Edinburgh, United Kingdom; 2. Western General Hospital, Edinburgh, United Kingdom; 3. Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

49

062

PHYSIOLOGICAL ADAPTATION TO ACUTE RELIEF OF ADVERSE RIGHT VENTRICULARLOADING CONDITIONS

Coats, L; Khambadone, S; Derrick, G; Deanfield, JE; Bonhoeffer, P; Taylor, AM

Great Ormond Street Hospital for Children, London, United Kingdom

063

EFFECTS OF GLYCERYL TRINITRATE TO LOWER CENTRAL ARTERIAL PRESSURERELATE TO ARTERIAL VASODILATION RATHER THAN REDUCTION IN PRE-LOAD

Seddon, M; Liu, B; Jiang, B; Chowienczyk, P

Cardiovascular Division, King’s College School of Medicine at Guy’s, King’s College and St Thomas’ Hospital, London, United Kingdom


Abstracts

Chair: Mr John Albarran and Ms Lynda Blue

064

AUDIT OF RATE OF RECURRENCE OF ATRIAL FIBRILLATION FOLLOWING DCCARDIOVERSION

Sevant, DJ; Dr Khokhar, A

Southend Hospital, Southend, United Kingdom

065

CARDIAC REHABIILITATION AND PATIENT EDUCATION FOLLOWING PRIMARY PCI

Thornley, AR1; Kunadian, B1; Lister, A1; Turley, AJ1; Moffitt, A1; Close, J2; Cave, M2; Hall, JA1; de Belder, MA1

1. The James Cook University Hospital, Middlesbrough, United Kingdom; 2. University Hospital of North Durham, Durham, United Kingdom

066

CORONARY HEART DISEASE PATIENTS’ PERCEPTION OF THEIR SYMPTOMS AND SENSE OF CONTROL BEFORE HOSPITAL DISCHARGE PREDICTS THEIRQUALITY OF LIFE IN THE LONG TERM

Lau-Walker, M; Cowie, M

Imperial College, London, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

48


Clinical Science

Chair: Dr Simon Redwood and Dr David Hildick-Smith

058

A PROSPECTIVE, MULTI-CENTRE CLINICAL TRIAL TO EVALUATE THE BIOSTARBIOABSORBABLE SEPTAL REPAIR IMPLANT FOR THE CLOSURE OF ATRIAL LEVELSHUNTS (1 YEAR FOLLOW UP).

Mullen, MJ1; Hildick-Smith, D2; De Giovanni, J3; Duke, C4; Hillis, S5; Morrison, L6; Jux, C7

1. Royal Brompton Hospital, London, United Kingdom; 2. Royal Sussex County Hospital, Brighton, United Kingdom; 3. Childrens Hospital Birmingham, Birmingham, United Kingdom; 4. Glenfield Rd Hospital, Leicester, United Kingdom; 5. Western Infirmary, Glasgow, United Kingdom; 6. Cardiothotacic Centre, Liverpool, United Kingdom; 7. Georg-August University, Goettingen, Germany

059

A PROSPECTIVE, MULTICENTRE, RANDOMISED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL TO EVALUATE THE EFFICACY OF PATENT FORAMENOVALE CLOSURE WITH THE STARFLEX® SEPTAL REPAIR IMPLANT TO PREVENTREFRACTORY MIGRAINE HEADACHES: THE MIST TRIAL

Dowson, AJ

King’s College Hospital, London, United Kingdom

060

COREVALVE PERCUTANEOUS AORTIC VALVE REPLACEMENT: NORTH AMERICANEXPERIENCE

Berry, C1; Asgar, A2; Marcheix, B2; Lamarche, Y2; Denault, AY2; Basmadjian, Arsene2;Ducharme, A2; Laborde, JC2; Bonan, R2

1. University of Glasgow, Glasgow, United Kingdom; 2. Montreal Heart Institute, Montreal, Canada

061

INCIDENCE OF RADIAL ARTERY ANATOMICAL VARIATION IN PATIENTSUNDERGOING TRANSRADIAL CORONARY ANGIOGRAPHY AND INTERVENTION:INFLUENCE ON PROCEDURAL OUTCOME

Lo, TSN1; Fountzopoulos, E1; Butler, R1; Hetherington, SL2; Zaman, A2; Perera, D3; Nolan, J1; Hildick-Smith, D3

1. University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom; 2. Freeman Hospital,Newcastle-upon-Tyne, United Kingdom; 3. Brighton and Sussex University Hospital, Brighton, United Kingdom

51


Cardiac physiologists and ACHD – session 1

Chair: Mr Peter Lewis

Adult congenital heart disease (ACHD) – today and tomorrowDr Catherine Head

Pulmonary valve replacement post calcification of pulmonary homograft – a case studyMr Pascal Browne

Exercise in adult congenital heart diseaseMs Katy Stewart and Prof Stewart Hillis

Development of the normal human heartDr Deborah Henderson

Alsh 11.00-12.45Young Research Workers’ Prize

Chair: Prof Nilesh Samani

Judges: Prof Anna DominiczakDr Adam FitzpatrickDr Giovanni MannProf Martin RothmanDr Jonathan Townend

Finalists: Basic scienceA P DhillonB K LeeC P Robinson

Clinical scienceD I GudmundsdottirE J JarmanF S Peterson

A

A STUDY OF THE RELATIONSHIP BETWEEN GAP JUNCTION EXPRESSION,CONDUCTANCE, AND CONDUCTION VELOCITY IN INTACT MYOCARDIUM

Dhillon, PS1; Shipolini, A2; Tsang, V3; Fry, CH4; Peters, NS1

1. St Mary’s Hospital, Imperial College, London, United Kingdom; 2. The London Chest, Queen Mary and Westfield College, London, United Kingdom; 3. The Heart Hospital, University College, London, United Kingdom; 4. University College, London, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

50

067

NURSE-LED CHEST PAIN TRIAGE – MEETING THE CHALLENGE OF ACUTECORONARY SYNDROMES

O’Neill, LM; Elder, DHJ; Dewhurst, NG; Currie, PF

Perth Royal Infirmary, PERTH, United Kingdom

068

THE CARDIAC EDUCATIONAL NEEDS AND COMPETENCIES OF EMERGENCY CARE NURSES

Cox, H

University of the West of England, Bristol, United Kingdom

069

CARDIAC ARRHYTMIAS IN WOMEN WITH PALPITATIONS OF PREGNANCYASSOCIATED WITH SYMPTOMS

Dhawan, A; Singh, J; Lewis, PS

Stepping Hill Hospital, Stockport, United Kingdom

Lomond 11.00-12.30Debate: Prophylactic antibiotic therapy to prevent endocarditis after dental

procedures is unnecessary and inappropriate

Chair: Dr Nicholas Boon and Dr Bernard Prendergast

For: Prof Graham Roberts

Against: Dr David Ramsdale

Hall 1 11.00-12.30British Society of Cardiovascular Magnetic Resonance (BSCMR)British Society for Heart Failure (BSH)

Workshop

When cardiovascular magnetic resonance (CMR) makes the difference – cases in heart failure: read with the experts

Chair: Prof Henry Dargie and Prof Dudley Pennell

Case presenters: Prof Henry DargieProf Stefan NeubauerProf Dudley PennellDr Sven PleinProf Reza Razavi

53


Audit guidelines and epidemiology

Chair: Prof John McMurray and Prof Tom Quinn

70

IMPROVING PROGNOSIS IN HEART FAILURE: TRENDS IN INCIDENTHOSPITALISATION FOR HEART FAILURE AND SUBSEQUENT SURVIVAL BETWEEN 1986 AND 2003

Jhund, PS1; MacIntyre, K1; Bishop , J2; Redpath, A2; Chalmers, J2; Capewell, S3; McMurray, JJV1

1. University of Glasgow, Glasgow, United Kingdom; 2. ISD Scotland, Edinburgh, United Kingdom; 3. University of Liverpool, Liverpool, United Kingdom

071

MULTI MODEL DIAGNOSTIC TESTS TO ASSESS HEART FAILURE USING ECG, CHEST X-RAY and ECHOCARDIOGRAM IN PATIENTS WITH SUSPECTED HEART FAILURE

Khan, NK1; Goode, KM1; Rigby, AS1; Torabi, A1; Clark, AL1; Freemantle, N2; Swedberg, K3; Komajda, M4; Follath, F5; Cleland, JGF1

1. University of Hull, Hull, United Kingdom; 2. University of Birmingham, Birmingham, United Kingdom; 3. Dept of Medicine Sahlgrenska University Hospital, Göteborg, Sweden; 4. CHU Pitié-Salpetrière, Paris, France; 5. Dept of Internal Medicine University Hospital, Zurich, Switzerland

072

INCIDENT ATRIAL FIBRILLATION AND NEW HEART FAILURE: THE CHICKEN OR THE EGG? INSIGHTS FROM THE IMPERIAL COLLEGE NEW AF STUDY

Martins, JL1; Fox, KF1; Wood, DA1; Lefroy, DC1; Collier, TJ2; Peters, NS1

1. Imperial College, London, United Kingdom; 2. London School of Hygiene & Tropical Medicine, London, United Kingdom

073

VERY HIGH PREVALENCE OF SLEEP APNOEA SYMPTOMS IN PATIENTS WHO HAVEUNDERGONE ELECTIVE ELECTRICAL CARDIOVERSION FOR ATRIAL FIBRILLATION

Haddadin, F1; Swamydass, D1; Thomas, SE1; Rees, GM1; Avery, PG1; Lewis, KE2

1. Carmarthenshire NHS Trust, Swansea, United Kingdom; 2. Swansea School of Medicine andCarmarthenshire NHS Trust, Swansea, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

52

B

GENOME-WIDE CELL-SPECIFIC EXPRESSION ANALYSIS IDENTIFIES THE INVOLVEMENT OF THE ADIPOCYTOKINE SIGNALING PATHWAY IN ATHEROSCLEROTIC PLAQUE RUPTURE

Lee, K1; Polvikoski, T2; Birchall, D2; Santibanez-Koref, M3; Mendelow, AD2; Keavney, B3

1. Institute of Human Genetics, Univerisity of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom; 2. Regional Neurosurgical Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom; 3. Institute of Human Genetics, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom

C

HYPERTROPHIC AND DILATED CARDIOMYOPATHY-CAUSING MUTATIONS OFTROPONIN AND αTROPOMYOSIN HAVE OPPOSITE EFFECTS ON THIN FILAMENTCALCIUM BINDING

Robinson, P; Watkins, H; Redwood, C

University of Oxford, Oxford, United Kingdom

D

DIRECT VASCULAR EFFECTS OF THROMBIN RECEPTOR ACTIVATION IN VIVO IN MAN

Gudmundsdottir, IJ; Ludlam, CA; Webb, DJ; Fox, KAA; Newby, DE

University of Edinburgh, Edinburgh, United Kingdom

E

NOVEL OBSERVATION OF REGIONS OF HIGHLY ORGANISED ACTIVATION AND STABLE FREQUENCY DURING CHRONIC ATRIAL FIBRILLATION IN THE HUMANLEFT ATRIUM: DO THEY REPRESENT FIXED DRIVERS?

Jarman, JWE; Wong, T; Spohr, H; Kojodjojo, P; Davies, JE; Segal, OR; Francis, DP; Davies, DW; Markides, V; Peters, NS

St Marys Hospital & Imperial College, London, United Kingdom

F

EVIDENCE FOR MICROVASCULAR DYSFUNCTION IN HYPERTROPHICCARDIOMYOPATHY – NEW INSIGHTS FROM MULTI-PARAMETRIC MAGNETICRESONANCE IMAGING

Petersen, SE1; Jerosch-Herold, M2; Hudsmith, LE1; Francis, JM1; Selvanayagam, JB1; Neubauer, S1; Watkins, H1

1. John Radcliffe Hospital/Dept. Cardiovascular Medicine/University of Oxford, Oxford, United Kingdom; 2. Advanced Imaging Research Center/Oregon Health & Science University/OR/US, Portland, United States

55


Audit guidelines and epidemiology

Chair: Dr Ameet Bakhai and Dr Howard Swanton

079

RISK STRATIFICATION IN REAL-WORLD ACUTE CORONARY SYNDROMES: DO CONVENTIONAL METHODS PREDICT EXTENT OF CORONARY ARTERY DISEASEAND NEED FOR REVASCULARISATION?

Johnson, TW; Dorman, S; West, NEJ

Gloucestershire Hospitals Foundation NHS Trust, Gloucester, United Kingdom

080

CONTEMPORARY ST ELEVATION MYOCARDIAL INFARCTION MANAGEMENT: RESULTS OF A HYBRID LYTIC PROGRAM ARE EQUVALENT TO PRIMARY PCI.

Freestone, B; Shufflebotham, A; Fountzopoulos, E; Lo, TS; Butler, R; Gunning, MG; Nolan, J

University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom

081

MANAGEMENT OF REPAIRED AND NATIVE MATERNAL AORTIC COARCTATIONDURING PREGNANCY

Bowater, SE1; Hudsmith, LE1; Knox, E2; Clift, PF1; Thompson, P2; Thorne, SA1

1. University Hospital Birmingham, Birmingham, United Kingdom; 2. Birmingham Women’s Hospital,Birmingham, United Kingdom

082

TRAINING BASIC LIFE SUPPORT TO SCHOOL CHILDREN USING MEDICAL STUDENTS AND TEACHERS IN A ‘PEER-TRAINING’ MODEL – RESULTS OF THE ‘ABC FOR LIFE’ PROGRAMME

Toner, P1; Connolly, M2; Laverty, L3; McGrath, P3; Connolly, D3; McCluskey, DR4

1. Craigavon Area Hospital, Craigavon, United Kingdom; 2. Antrim Area Hospital, Antrim, United Kingdom; 3. Queen’s University Belfast, Belfast, United Kingdom; 4. Royal Victoria Hospital, Belfast, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

54

074

PREVALENCE OF DEPRESSION AND ANXIETY AMONG PATIENTS WITH ATRIALFIBRILLATION: EFFECTS ON SIX-MONTH QUALITY OF LIFE

Thrall, G1; Lane, DA1; Carroll, D2; Lip, GYH1

1. University Department of Medicine, City Hospital, Birmingham, United Kingdom; 2. University of Birmingham, Birmingham, United Kingdom

075

THE ROLE OF MODERATE ALCOHOL INTAKE IN FIRST DETECTED ATRIALFIBRILLATION: THE IMPERIAL COLLEGE NEW AF STUDY

Martins, JL1; Fox, KF1; Wood, DA1; Lefroy, DC1; Collier, TJ2; Peters, NS1

1. Imperial College, London, United Kingdom; 2. London School of Hygiene & Tropical Medicine, London,United Kingdom

076

THE EFFECT OF OBSTRUCTIVE SLEEP APNOEA ON LEFT ATRIAL AND LEFTVENTRICULAR STRUCTURE

Kesavan, S; Green, R; Mansfield, R

Royal United Hospital Bath NHS Trust, Bath, United Kingdom

077

PREVALENCE OF HYPERTROPHIC CARDIOMYOPATHY IN ELITE ATHLETES

Basavarajaiah, S1; Wilson, M2; Carby, L2; Shah, A1; Sharma, S1

1. Kings College Hospital, London, United Kingdom; 2. University hospital Lewisham, London, United Kingdom

078

PREVALENCE OF CARCINOID HEART DISEASE IN THE MODERN ERA

Bhattacharyya, S1; Toumpanakis, C2; Caplin, M2; Davar, J1

1. Department of Cardiology, Royal Free Hospital, London, United Kingdom; 2. Neuroendocrine Tumour Unit,Royal Free Hospital, London, United Kingdom

57


Paediatric, adult congenital heart disease and valve disease

Chair: Dr Kate English and Dr Graham Stuart

088

INFANT ASSESSMENT FOR CARDIAC TRANSPLANTATION

Kirk, CR; Hasan, A; Parry, G; Cassidy, J; Wrightson, N

Freeman Hospital, Newcastle upon Tyne, United Kingdom

089

PLANAR CELL POLARITY SIGNALLING PLAYS CRUCIAL ROLES IN OUTFLOW TRACT DEVELOPMENT

Henderson, DJ; Phillips, HM

Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

090

PREDICTION OF FETAL COARCTATION OF THE AORTA FROM THE THREE VESSELAND TRACHEAL VIEW

Matsui, H1; Pasquini, L1; Seale, A2; Mellander, M2; Roughton, M2; Ho, SY2; Gardiner, HM1

1. Faculty of Medicine, Imperial College at Queen Charlotte’s & Chelsea Hospital, London, United Kingdom; 2. Royal Brompton Hospital, London, United Kingdom

091

RENAL FUNCTION AND OUTCOME FROM VALVE SURGERY

Gibson, PH; Chiwara, M; Croal, BL; Cuthbertson, BH; Small, GR; Gibson, G; Jeffrey, RR; Buchan, KG; El-Shafei, H; Hillis, GS

Aberdeen Royal Infirmary, Aberdeen, United Kingdom

092

THE IMPACT OF PERCUTANEOUS ATRIAL SEPTAL DEFECT CLOSURE IN THE OLDER POPULATION

Khan, A; Tan, JL; Li, W; Spence, M; Mullen, M

Royal Brompton Hospital, London, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

56

083

DOES A STRATEGY OF SELECTIVE BIOMARKER TESTING FOLLOWING PCI MISS PROGNOSTICALLY IMPORTANT PROCEDURE-RELATED MYOCARDIALINFARCTIONS?

Berry, C; L. L’Allier, P; Ibrahim, R; Bilodeau, L; Kedhi, E; Mikhail, R; Lavoie, J; Dupuis, J; Lambert, J

Montreal Heart Institute, Montreal, Canada

084

FEASIBILITY OF DIAGNOSING AND QUANTIFYING METABOLIC SYNDROME IN CONSECUTIVE ACUTE MEDICAL ADMISSIONS

Balakrishnan, G1; Weerasinghe, AI1; Zacharias, K1; Mathers, J1; Joseph, N1; Sudhir, R1;Andrews, C1; Katz, J1; Bakhai, A2

1. Barnet General Hospital, Barnet, United Kingdom; 2. Barnet General Hosp / AMORE study group, London, United Kingdom

085

USING CASE-MIX ADJUSTED FUNNEL PLOTS OF 30 DAY MORTALITY FOR ACUTECORONARY SYNDROMES TO EXPLORE HOSPITAL PERFORMANCE

Gale, CP1; Ramachandra, R2; Baliga, V2; Dudley, F2; Gale, RP1; Roberts, AP3; Batin, PD2;Wilson, JI2; Hall, AS1

1. Leeds General Infirmary, Leeds, United Kingdom; 2. Pinderfields Hospital, Wakefield, United Kingdom; 3. University of Durham, Durham, United Kingdom

086

SEX DIFFERENCE IN THE RELATIONSHIP BETWEEN SOCIOECONOMIC DEPRIVATIONAND FATAL COMPARED TO NON-FATAL MYOCARDIAL INFARCTION

Jhund, PS; MacIntyre, K; McMurray, JJV

University of Glasgow, Glasgow, United Kingdom

087

USING THE MYOCARDIAL INFARCTION NATIONAL AUDIT PROJECT (MINAP)DATABASE TO VALIDATE ACUTE CORONARY SYNDROME RISK SCORES BY SUBGROUP RISK

Gale, CP1; Manda, SOM2; Weston, CF3; Birkhead, JS4; Batin, PD5; Hall, AS1

1. Yorkshire Heart Centre, Leeds General Infirmary, Leeds, United Kingdom; 2. Centre for Biostatistics,University of Leeds, Leeds, United Kingdom; 3. Department of Cardiology, Singleton Hospital, Swansea,United Kingdom; 4. Department of Cardiology, Northampton General Hospital, Northmanpton, United Kingdom; 5. Department of Cardiology, Pinderfilds General Hospital, Wakefield, United Kingdom

59

098

LEFT VENTRICULAR REVERSE REMODELLING AFTER CARDIACRESYNCHRONISATION THERAPY IN HEART FAILURE PATIENTS WITH A NARROW QRS DURATION

Williams, LK1; Ellery, SM2; Stegemann, B3; Patel, KC1; Leyva, F4; Paul, V5; Frenneaux, MP1

1. University of Birmingham, Birmingham, United Kingdom; 2. St Peters Hospital, Chertsey, United Kingdom; 3. Medtronic Bakken Research Centre, Maastricht, United Kingdom; 4. Good Hope Hospital, Birmingham, United Kingdom; 5. St Peters Hospital, Chertsey, United Kingdom

099

MEDIUM-TERM ECHOCARDIOGRAPHIC ASSESSMENT OF HEART FAILURE PATIENTSIMPLANTED WITH AN AXIAL FLOW LVAD

Jin, XY1; Westaby, S1; Pepper, JR2; Poole-Wilson, P2; Banning, A1

1. John Radcliffe Hospital, Oxford, United Kingdom; 2. Royal Brompton Hospital, London, United Kingdom

100

COMMON ABNORMALITIES OF INSULIN ACTION IN PATIENTS WITH DIABETES AND HEART FAILURE

Cook, SA1; Khan, T1; Mongillo, M1; Leccisotti, L1; Strickland, N1; Rosenzweig, A2; Punjabi, P1; Camici, P1

1. Imperial College, London, United Kingdom; 2. Harvard University, Boston, United States

101

THE RISK ASSOCIATED WITH DIABETES MELLITUS IN PATIENTS WITH PRESERVEDAND LOW EJECTION FRACTION HEART FAILURE: AN ANALYSIS OF THECANDESARTAN IN HEART FAILURE ASSESSMENT OF REDUCTION IN MORTALITYAND MORBIDITY (CHARM) PROGRAM

MacDonald, MR1; Varyani, F2; Carlsson, J3; Petrie, MC1; Ostergren, J4; Michelson, EL5;Solomon, SD6; Granger, CB7; Swedberg, K8; Pfeffer, M6; Yusuf, S9; McMurray, JJV2

1. Glasgow Royal Infirmary, Glasgow, United Kingdom; 2. Western Infirmary, Glasgow, United Kingdom; 3. Astrazeneca, Molndal, Sweden; 4. Karolinska Hospital, Stockholm, Sweden; 5. Astrazeneca, Wilmington,United States; 6. Brigham & Women’s Hospital, Boston, United States; 7. Duke University Medical Center,Durham, United States; 8. Sahlgrenska University Hospital, Goteborg, Sweden; 9. HGM-McMaster Clinic,Hamilton, Canada

102

IRON METABOLISM IS IMPAIRED IN HEART FAILURE IRRESPECTIVE OFHAEMOGLOBIN CONCENTRATION AND LEFT VENTRICULAR EJECTION FRACTION

Murphy, CL1; Lundmark, EM2; Fitzsimons, EJ3; Jardine, AG3; Sattar, N3; McMurray, JJV1

1. Glasgow Cardiovascular Research Centre, Glasgow, United Kingdom; 2. Western Infirmary, Glasgow, United Kingdom; 3. University Of Glasgow, Glasgow, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

58

093

ARRHYTHMIA BURDEN IN ADULTS WITH CONGENITAL HEART DISEASE IN A LEVEL 2 GUCH CENTRE

Felix, PAM; Howard, S; Freeman, LJ

Norfolk and Norwich University Hospital NHS Trust, Norwich, United Kingdom

094

ROLE OF MODIFIED VALSALVA MANOUVRE IN THE DIAGNOSIS OF PATENTFORAMEN OVALE BY TRANSOESOPHAGEAL ECHOCARDIOGRAPHY

Velupandian, UM1; Khiani, R1; Ray, SG2; Morris, J2; Heagerty, AM1; McCollum, CN1

1. University of Manchester, Manchester, United Kingdom; 2. South Manchester University Hospital,Manchester, United Kingdom

095

THE TIME COURSE OF IMPROVEMENT IN ECG STRAIN PATTERN AFTER AVR FOR AS AND ITS UNDERLYING MECHANISMS

Du, X; Jin, XY

John Radcliffe Hospital, Oxford, United Kingdom

096

LEFT DOMINANT CORONARY ARTERIAL SYSTEM IN AORTIC STENOSIS – AN ASSOCIATION, CAUSE OR EFFECT

Innasimuthu, AL1; Morris, G2; Rao, GK1; Fox, JP3; Perry, RA4

1. University Hospital Aintree, Liverpool, United Kingdom; 2. Division of Cardiovascular and EndocrineSciences, University of Manchester, Manchester, United Kingdom; 3. Southport and Ormskirk NHS Trust,Southport, United Kingdom; 4. The Cardiothoracic Centre, Liverpool, United Kingdom


Heart failure and cardiac transplantation

Chair: Prof John Cleland and Prof Chim Lang

097

IS HEART FAILURE A PROCESS OF RELENTLESS PROGRESSIVE VENTRICULARREMODELLING AND FUNCTIONAL DETERIORATION?

Lewis, NT; Barker, D; Schlosshan, D; Tan, LB

Leeds General Infirmary, Leeds, United Kingdom

61

107

IMPAIRED GLUCOSE TOLERANCE IS ASSOCIATED WITH ENDOTHELIAL DAMAGEFOLLOWING ACUTE MYOCARDIAL INFARCTION

Jessani, S; Millane, T; Lip, GYH

City Hospital, Birmingham, United Kingdom

108

THROMBOGENICITY IN TYPE 2 DIABETES AND CORONARY ARTERY DISEASE

Natarajan, A1; Marshall, SM2; Badimon, JJ3; Zaman, AG4

1. Newcastle University and Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2. Newcastle University, Newcastle upon Tyne, United Kingdom; 3. Mount Sinai School of Medicine, New York, United States; 4. Freeman Hospital, Newcastle upon Tyne, United Kingdom

109

ELEVATED NEOPTERIN AFTER ACUTE CORONARY SYNDROMES PREDICTS LONG-TERM RISK OF DEATH OR NON-FATAL CORONARY EVENTS: ANALYSIS FROMPROVE IT-TIMI 22

Ray, KK1; Morrow, DA1; Cannon, CP1; Sabatine, MS1; Shui, A2; Braunwald, E1

1. Harvard Medical School, Boston, United States; 2. Brigham and Women’s Hospital, Boston, United States

110

COST EFFECTIVENESS OF EZETIMIBE CO-ADMINISTRATION VS DOUBLING STATINDOSE IN PATIENTS NOT AT CHOLESTEROL TARGETS ON STATIN MONOTHERAPY IN THE UK

Brady, AJB1; Davies, GM2; Urdahl, H3; Yin, D4; Alemao, E4; CooK, JR2

1. Department of Medical Cardiology, Glasgow Royal Infirmary, Glasgow, United Kingdom; 2. Health Economics Statistics, Merck and Co., Upper Gwynedd, PA, United States; 3. Outcomes Research, MSD, Hoddesdon, Hertfordshire, United Kingdom; 4. Outcomes Research, Merck and Co., Whitehouse Station, United States

111

MINOR TROPONIN T RISE IN NEW ONSET ATRIAL FIBRILLATION SIGNIFICANTLYINCREASES FUTURE CARDIOVASCULAR RISK

Dhawan, A; Ganaraj, L; Khan, SQ; Ahmad, I; Singh, J; Malik, N; Lewis, PS

Stepping Hill Hospital, Stockport, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

60

103

EFFECT OF INTRAVENOUS IRON SUCROSE ON EXERCISE TOLERANCE IN ANAEMIC AND NON-ANAEMIC PATIENTS WITH SYMPTOMATIC CHRONIC HEART FAILURE AND IRON DEFICIENCY (FERRIC-HF): A RANDOMISED, CONTROLLED, OBSERVER-BLINDED TRIAL

Okonko, DO1; Greszlo, A2; Witkowski, T2; Mandal, AKJ3; Slater, RM3; Roughton, M1; Foldes, G1; Banasiak, W2; Missouris, CG3; Poole-Wilson, PA1; Anker, SD4; Ponikowski, P2

1. Clinical Cardiology, NHLI, Imperial College London, London, United Kingdom; 2. Cardiac Department,Military Hospital, Wroclaw, Poland; 3. Department of Cardiology, Wexham Park Hospital, Slough, United Kingdom; 4. Department of Cardiology, Charité Campus Virchow-Klinikum, Berlin, Germany

104

HEART TRANSPLANTATION IN THE CURRENT ERA – A 10-YEAR PERSPECTIVE

Hamour, IM; Omar, F; Panicker, MG; Banerjee, R; Mitchell, AG; Khaghani, A; Dreyfus, GD; Banner, NR

The Royal Brompton and Harefield NHS Trust, Harefield Hospital, Harefield, United Kingdom

105

THE CHANGING RISK/BENEFIT RATIO OF ENDOMYOCARDIAL BIOPSIES WITHIMPROVED IMMUNOSUPPRESSION AFTER HEART TRANSPLANTATION

Hamour, IM1; Panicker, MG2; Banerjee, R1; Bell, AD1; Burke, MM1; Banner, NR1

1. The Royal Brompton and Harefield NHS Trust, Harefield Hospital, Harefield, Middlesex, United Kingdom; 2. The Royal Brompton and Harefield NHS Trust, Harefield Hospital, Harefield, Middlesex, United Kingdom


Medical treatment of coronary artery disease and acute coronary syndromes (not intervention)

Chair: Dr Mark De Belder and Dr John Townend

106

THE ROLE OF SECONDARY PREVENTION STRATEGIES IN PATIENTS WITH DIABETESMELLITUS SUSTAINING AN ACUTE CORONARY SYNDROME: TIME FOR A CRITICALREAPPRAISAL?

Cubbon, RM1; Rajwani, A1; Grant, PJ1; Wheatcroft, SB1; Barth, JH2; Kearney, MT1; Hall, AS1

1. The University of Leeds, Leeds, United Kingdom; 2. Leeds General Infirmary, Leeds, United Kingdom

63

Hall 1 12.45-13.45Sponsored symposiumSponsored by Schering Plough/MSD

Balance: the art of cholesterol management

Chair: Dr Adrian Brady

Tailoring treatment to optimise clinical outcomesProf John Kastelein

Striking the balance: cholesterol synthesis and absorptionDr Clive Weston


Boisdale 12.45-13.45How to find new genes for cardiovascular disease (and why it is important)

Chair: Prof Jeremy Pearson

Cohort selection for human studiesDr Bernard Keavney

Genome-wide transcript profiling and linkage analysisProf Timothy Aitman

Carron 12.45-13.45How to select cases for percutaneous closure of the inter-atrial septum

Chair: Dr Simon Ray

Patent foramen ovaleDr David Northridge

Atrial septal defectDr David Hildick-Smith

Dochart 12.45-13.45How to manage the survivors of out-of-hospital cardiac arrest

Chair: Dr Neil Davidson

Predicting neurological outcomeDr David Swan

Cardiological assessment and treatmentDr Neil Grubb and Dr Brian Cook

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

62

112

TROPONIN ELEVATION IN NON-ACUTE CORONARY SYNDROMES: OXVASC DATA

Ryding, ADS1; Silver, LE2; Banning, AP1; on behalf the OXVASC study3

1. John Radcliffe Hospital, Oxford, United Kingdom; 2. OXVASC study, Radcliffe Infirmary, Oxford, UnitedKingdom; 3. Radcliffe Infirmary, Oxford, United Kingdom

113

HEART RATE LOWERING ACTION OF IVABRADINE DEPENDS ON BASELINE HEARTRATE: MECHANISM OF LOW INCIDENCE OF EXCESSIVE BRADYCARDIA DURINGTHERAPY WITH IVABRADINE

Savelieva, I1; Borer, JS2; Camm, AJ1

1. St George’s University of London, London, United Kingdom; 2. Weill Medical College, Cornell University, New York, United States

114

EVIDENCE FOR A STRONG ANTIARRHYTHMIC EFFECT OF SPIRONOLACTONE IN PATIENTS WITH CORONARY ARTERY DISEASE BUT WITHOUT HEART FAILURE

Shah, NC1; Donnan, PD2; Pringle, SD3; Struthers, AD1

1. University of Dundee / Ninewells Hospital, Dundee, United Kingdom; 2. University of Dundee, Dundee,United Kingdom; 3. Ninewells Hospital, Dundee, United Kingdom


BANCC AGMAnnual review, incoming President and Council


Lomond 12.45-13.45Sponsored symposiumSponsored by Pfizer

Debate: Cholesterol targets of 4 and 2mmol/L should be national policy for patientswith established cardiovascular disease

Chair: Prof Neil Poulter

For: Dr Anthony Wierzbicki

Against: Dr James Moon

65

Lomond 14.00-15.30British Cardiovascular Society (BCS)European Society of Cardiology (ESC)

Acute coronary syndromes: the implementation of guidelines to clinical practice

Chair: Dr Nicholas Brooks and Prof Kim Fox

New ESC guidelines on non-ST-elevation acute coronary syndromesProf Jean-Pierre Bassand

PCI for ST elevation and ST depression acute coronary syndromesProf Petr Widimsky

New anti-thrombotic therapies in acute myocardial infarction Dr Robert Storey

NSTEMI vs STEMI: the widening care gapProf Adam Timmis on behalf of the MINAP Academic Group

Hall 1 14.00-15.30Heart Rhythm UK (HRUK)

Workshop

Challenges and complications in device therapy

Chair: Dr Michael Gammage and Dr Nicholas Linker

Case 1Dr Neil Sulke

Case 2Dr Chris Plummer

Case 3Dr Francis Murgatroyd



Cardiac physiologists and ACHD – session 2

Chair: Ms Virginia Anderson

Imaging in congenital heart diseaseDr Hamish Walker

Cardiac resynchronisation therapy in congenital heart diseaseMr Stuart Lilley

Percutaneous intervention – closure devicesDr Michael Mullen

Arrhythmias in adult congenital heart diseaseDr Derek Connelly


CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

64

Gala 12.45-13.45How to improve your presentation skills

Chair: Dr Huon Gray

Effective deliveryProf John Camm

Preparing a powerpoint presentationDr Anthony Gershlick


Inequalities and cardiovascular disease

British Association for Nursing in Cardiac Care (BANCC)Heart Care Partnership UK (HCP UK)British Association for Cardiac Rehabilitation (BACR)British Heart Foundation (BHF)

Working together for women’s heart health

Chair: Mr David Geldard and Ms Michaela Nuttall

BCS working party recommendationsDr Jane Flint

Joint implementation with cardiac network patient and carer partnershipsMs Beth Greenaway

Will a focus on women revolutionise integrated pathway development?Mr John Albarran

Moving forward with rehab, prehab and prevention in womenMrs Bernie Downey

Global perspective of progressProf Jennifer Mieres

67

117

INEQUITY OF ACCESS TO CARDIAC PACING: RESULTS OF A NATIONAL SURVEY

McComb, JM1; Plummer, CJ1; Charles, RG2; Cunningham, MW2; Cunningham, AD2

1. Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2. Central Cardiac Audit Database, London, United Kingdom

118

SAFETY OF SPIRONOLACTONE WITH ACE INHIBITORS / ANGIOTENSIN RECEPTORBLOCKADE IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Edwards, NC1; Steeds, RP2; Ferro, CJ2; Townend, JN2

1. University of Birmingham, Birmingham, United Kingdom; 2. University Hospital Birmingham, Birmingham, United Kingdom

119

A 15 YEAR AUDIT OF ACUTE TYPE A AORTIC DISSECTION – HAVE THE OUTCOMESCHANGED WITH TIME?

Narayan, P; Rogers, CA; Caputo, M; Angelini, GD; Bryan, AJ

Bristol Heart Institute, Bristol, United Kingdom

120

CARDIOVASCULAR MORTALITY IN DIALYSIS PATIENTS

Vrapi, F1; Bakhai, A2; Kabunga, P1; Buscombe, J1; Davenport, A1; Coghlan, JG1

1. Royal Free Hospital, London, United Kingdom; 2. Barnet & Chase Farm and Royal Free Hospital, London, United Kingdom

121

DOES THE LEVINE SIGN AID DIAGNOSIS OF ANGINA IN A RAPID-ACCESS CHESTPAIN CLINIC?

Wheeler, S; Halliday, A; West, NEJ

Gloucestershire Hospitals NHS Foundation Trust, Gloucester, United Kingdom

122

A REPORT ON THE REFERRAL RATE OF PATIENTS SEEN IN A RAPID ACCESS CHESTPAIN CLINIC FOR ENDOSCOPY – ARE WE CREATING WORK FOR OUR COLLEAGUES?

Tenkorang, J1; Tataree, D2; Wood, DA1; Bansi, D1; Thillainayagam, AV1; Fox, KF1

1. Imperial College, London, United Kingdom; 2. Charing Cross Hospital, London, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

66

Alsh 14.00-15.30British Society for Heart Failure (BSH)British Society of Echocardiology (BSE)British Society for Cardiovascular Research (BSCR)

Cytotoxic chemotherapy and the heart

Chair: Dr Kevin Fox and Dr Theresa McDonagh

Basic mechanisms of cardiotoxicity with anthracyclines and trastuzimab Dr Peter Sugden

Cardiotoxicity with anthracyclines and trastuzimab – the clinical view Dr Perry Elliot

Anthracyclines and trastuzimab – why we like it and how we cope when the heartdoesn’t – the view from oncologyDr Peter Canney

How can we detect and monitor it? Echocardiography and other modalities Dr Richard Steeds



Chair: Dr Carl Brookes and Dr David Cunningham

115

AN AUDIT OF PACING PRACTICE IN THE 33 CARDIAC NETWORKS SERVINGENGLAND AND WALES

Plummer, CJ1; Cunningham, AD2; Cunningham, MW2; Charles, RG2; McComb, JM1

1. Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2. National Pacemaker and ICD Database,Central Cardiac Audit Database, London, United Kingdom

116

LACK OF KNOWLEDGE OF PACEMAKER INDICATIONS AT THE FRONT LINE

McComb, JM; Plummer, CJ


69

127

LATE STENT THROMBOSIS: LONG TERM CLINICAL RESULTS OF THE ELUTESPOLYMER-FREE DRUG-ELUTING STENT TRIAL

Swanson, Neil; Carver, A; Kelly, DJ; Gershlick, AH

Glenfield Hospital, Leicester, United Kingdom

128

SERUM CREATININE CONCENTRATION IS AN INDEPENDENT PREDICTOR OF LONG-TERM MORTALITY FOLLOWING PERCUTANEOUS CORONARYINTERVENTION; DRUG-ELUTING STENT IMPLANTATION REDUCES THIS RISK

Alahmar, AE; Shaw, M; Egred, M; Roberts, EB; Andron, M; Grayson, AD; Antony, R; Albouaini, K; Jackson, M; Stables, RH; Perry, A

Cardiothoracic Centre Liverpool, Liverpool, United Kingdom

129

INDIVIDUAL RESPONSES TO ASPIRIN USING A NOVEL METHOD OF THROMBELASTOGRAM ANALYSIS: HYPORESPONSIVENESS OR POOR COMPLIANCE?

Hobson, AR; Dawkins, KD; Curzen, NP

Wessex Cardiac Unit, Southampton University Hospitals Trust, Southampton, United Kingdom

130

MARKED HETEROGENEITY OF INDIVIDUAL RESPONSES TO LOADING DOSECLOPIDOGREL EMPLOYING A NOVEL POINT OF CARE TEST

Hobson, AR; Dawkins, KD; Curzen, NP

Wessex Cardiac Unit, Southampton University Hospitals Trust, Southampton, United Kingdom


Echocardiography

Chair: Dr John Chambers and Prof Catherine Otto

131

RESTING MYOCARDIAL BLOOD FLOW NOT MYOCARDIAL FLOW RESERVE PREDICTS HIBERNATING MYOCARDIUM: A QUANTITATIVE MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY STUDY

Hickman, M; Burden, L; Senior, R


CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

68

123

PROFILING ENGLISH HOSPITAL MORTALITY RATES FOR ACUTE CORONARYSYNDROMES USING THE MYOCARDIAL INFARCTION NATIONAL AUDIT PROJECT(MINAP) DATABASE

Gale, CP1; Manda, SOM2; Greenwood, D2; Gilthorpe, MS2; Weston, C3; Birkhead, J4; Batin, PD5; Hall, AS1

1. Yorkshire Heart Centre, Leeds General Infirmary, Leeds, United Kingdom; 2. Biostatistics Unit, University of Leeds, Leeds, United Kingdom; 3. Department of Cardiology, Singleton Hospital, Swansea, United Kingdom; 4. Department of Cardiology, Northampton General Hospital, Northampton, United Kingdom; 5. Department of Cardiology, Pinderfields General Hospital, Wakefield, United Kingdom


Interventional cardiology

Chair: Dr Adrian Banning and Dr Sarah Clarke

State of the art: Stent thrombosisDr Martyn Thomas

124

NO DIFFERENCE IN 2 YEARS MORTALITY BETWEEN DRUG-ELUTING STENT AND BARE-METAL STENT IMPLANTATION IN “REAL WORLD”

Alahmar, AE; Grayson, AD; Andron, M; Naji, A; Jackson, M; Palmer, ND; Perry, RA

Cardiothoracic Centre Liverpool, Liverpool, United Kingdom

125

A RANDOMISED TRIAL OF DRUG ELUTING VERSUS BARE METAL STENTS IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (DEVINE)

Pitt, JE; Reeve, M; Whitlam, H; Pulikal, G; Ment, J; El Gaylani, N; Beattie, J; Murray, G; Pitt, M

Heart of England NHS Foundation Trust (Heartlands), Birmingham, United Kingdom

126

COMPARISON OF CLINICAL OUTCOMES IN SMALL VESSEL PERCUTANEOUSCORONARY INTERVENTION BEFORE AND AFTER THE INTRODUCTION OF DRUG-ELUTING STENTS

Antony, R1; Aziz, S2; Kia, R3; Grainger, R1; Stables, RH1

1. The Cardiothoracic Centre, Liverpool, United Kingdom; 2. Royal Blackburn Hospital, Blackburn, UnitedKingdom; 3. Aintree University Hospital, Liverpool, United Kingdom

71

138

PARTIAL VOLUME EFFECT NOT HYPOPERFUSION IS THE CAUSE OF PERFUSIONDEFECTS ON SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IN LEFTBUNDLE BRANCH BLOCK PATIENTS WITHOUT CORONARY ARTERY DISEASE: A QUANTITATIVE MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY STUDY

Hayat, SA; Dwivedi, G; Lim, TK; Jacobsen, AN; Senior, R


139

ASSESSMENT OF VENTRICULAR FUNCTION IN ATRIAL FIBRILLATION: SINGLE BEATSWITH EQUAL PRECEDING AND PRE-PRECEDING R-R INTERVALS ALLOW ACCURATEESTIMATION OF LEFT VENTRICULAR SYSTOLIC FUNCTION

Bajpai, A; Kiotsekoglou, A; Savelieva, I; Dougal, C; Rowland, E; Sutherland, GR; Camm, AJ

St George’s, University of London, London, United Kingdom


EP intervention and ablation

Chair: Prof John Camm and Dr Tim Betts

140

PHYSIOLOGICAL EVIDENCE OF THE “SECOND FACTOR” IN ATRIAL REMODELING IS ACCOMPANIED BY LOCALISED CONDUCTION ABNORMALITIES IN THE CHRONICGOAT MODEL OF AF

Kirubakaran, S1; Hall, MCS1; Peters, NS2; Garratt, CJ1

1. Manchester Heart Centre, Manchester, United Kingdom; 2. Imperial College, London, United Kingdom

141

RELATIVE CONTRIBUTION OF ELECTRICAL AND NON-ELECTRICAL (STRUCTURAL)REMODELING ON THE AF CIRCUIT SIZE IN THE CHRONIC GOAT MODEL OF AF

Kirubakaran, S1; Hall, MCS1; Peters, NS2; Garratt, CJ1

1. Manchester Heart Centre, Manchester, United Kingdom; 2. Imperial College, London, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

70

132

IDENTIFYING RESPONDERS TO CRT – ARE WE USING THE RIGHT METHOD?

Parsai, C1; Bijnens, B2; Sutherland, GR1; Baltabaeva, A1; Marciniak, M1; Marciniak, A1; Anderson, L1

1. St George’s Hospital, London, United Kingdom; 2. University of Leuven, Leuven, Belgium

133

2D-STRAIN DERIVED ANTEROSEPTUM TO POSTERIOR WALL DELAY PREDICTSREVERSE REMODELLING POST CARDIAC RESYNCHRONISATION THERAPY

Artis, NJ1; Oxborough, DL1; Tan, LB1; Williams, G2; Pepper, CB2

1. University of Leeds, Leeds, United Kingdom; 2. Leeds General Infirmary, Leeds, United Kingdom

134

QUANTIFICATION OF CARDIAC DYSSYNCHRONY AT REST AND AFTER PEAKEXERCISE IN HEART FAILURE PATIENTS

Silberbauer, J1; Beale, L2; Brickley, G2; Taggu, W1; Veasey, RA1; Patel, NR1; Sulke, AN1; Lloyd, GW1

1. East Sussex Hospitals NHS Trust, Eastbourne, United Kingdom; 2. University of Brighton, Eastbourne,United Kingdom

135

EXTENT OF MYOCARDIAL VIABILITY DETECTED BY MYOCARDIAL CONTRASTECHOCARDIOGRAPHY EARLY AFTER ACUTE MYOCARDIAL INFARCTION IS AN INDEPENDENT PREDICTOR OF MORTALITY AND RE-INFARCTION

Dwivedi, G1; Hayat, S1; Janardhanan, R1; Ruperalia, N2; Lim, TK1; Senior, R1

1. Northwick Park Hospital, Harrow, United Kingdom; 2. Northwick Park Hospital, Harrow, United States

136

CONTRAST ULTRASONOGRAPHY: A NOVEL APPLICATION FOR THE ASSESSMENT OF GRAFT PERFUSION

Greaves, K1; Sharma, S1; Anand, R1; Bowden, J1; Ilankovan, V1; Hickman, M1; Walji, S1; Senior, R2

1. Poole Hospital, Poole, United Kingdom; 2. Northwick Park, Harrow, United Kingdom

137

STRESS ECHOCARDIOGRAPHY IN THE DISTRICT HOSPITAL SETTING: A COST-EFFECTIVENESS ANALYSIS

Wennicke, N1; Senior, R2; Greaves, K1

1. Poole Hospital, Poole, United Kingdom; 2. Northwick Park Hospital, Harrow, United Kingdom

73

147

VIDEO-ASSISTED THORACOSCOPIC ABLATION FOR TREATMENT OF ATRIALFIBRILLATION

Avlonitis, VS; Murray, S; Hunter, S

James Cook University Hospital, Middlesbrough, United Kingdom

148

INITIAL EXPERIENCE OF CATHETER ABLATION USING A NOVEL REMOTELYSTEERABLE CATHETER SHEATH SYSTEM

Koa-Wing, M1; Kanagaratnam, P1; Wallace, D2; Lim, PB1; Willis, B3; Alton, L3; Aston, K3; Sciberras, P3; Kojodjojo, P1; Wright, M3; Kaba, RA3; Peters, NS1; Davies, DW3

1. St. Mary’s Hospital and Imperial College, London, United Kingdom; 2. Hansen Medical, Inc., Mountain View, United States; 3. St. Mary’s Hospital, London, United Kingdom


Nuclear, MRI and CT

Chair: Dr Charles Peebles and Dr Sven Plein

149

DEMONSTRATION OF CORONARY VENOUS ANATOMY USING CARDIAC MAGNETICRESONANCE IMAGING

Younger, J; Crean, A; Plein, S; Ball, S; Greenwood, J

Leeds University, Leeds, United Kingdom

150

THE FEASIBILITY OF WHOLE HEART MAGNETIC RESONANCE CORONARYANGIOGRAPHY TO DETERMINE THE COURSE OF ANOMALOUS CORONARYARTERIES

Younger, J; Crean, A; Ball, S; Plein, S; Greenwood, J

Leeds University, Leeds, United Kingdom

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

72

142

DOES CONDUCTION DELAY IN THE RIGHT VENTRICULAR OUTFLOW TRACTUNDERLIE ARRHYTHMOGENESIS IN BRUGADA SYNDROME? A NON-CONTACTENDOCARDIAL MAPPING STUDY

Ahmed, Akbar K1; Rogers, DP1; Uddin, MM2; Lowe, MD1; Dhinoja, M1; Chow, AW1; Lambiase, P1

1. Heart Hospital,UCL, London, United Kingdom; 2. Kettering Genral Hospital, Kettering, United Kingdom

143

COMPUTER ASSISTED ELECTRICAL MAPPING OF ATRIAL TACHYARRHYTHMIAS IN PATIENTS WITH SURGICALLY CORRECTED TETRALOGY OF FALLOT

Raine, D1; O’Sullivan, J1; Chaudhari, M1; Hamilton, L2; Hasan, A2; Bourke, JP1

1. Department of Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2. Department of Paediatric Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom

144

CAN UNSTABLE ARRHYTHMIAS BE DETECTED BY CHANGES IN INTRACARDIACIMPEDANCE?

Mudawi, TO1; Kaye, GC2; Houghton, T3; Lippert, M4; Czygan, Gerald4; Edgar, Deborah5

1. Cardio-Thoracic Centre, Liverpool, United Kingdom; 2. Princess Alexandra Hospital, Woolloongabba,Australia; 3. Hull Royal Infirmary, Hull, United Kingdom; 4. Biotronik GmbH & Co KG, Erlangen, Germany; 5. Biotronik UK, Bicester, United Kingdom

145

WHY DO SOME PATIENTS WITH WOLFF-PARKINSON-WHITE SYNDROME PRESENTLATER IN LIFE?

Boodhoo, L; Pradhan, D; Hall, M; Snowdon, R; Waktare, J; Todd, DM

The Cardiothoracic Centre, Loverpool, United Kingdom

146

CT GUIDED TRANSSEPTAL LEFT HEART CATHETERISATION FOR LEFT ATRIALABLATION: A NOVEL TECHNIQUE

Graham, Lee1; Melton, Iain2; MacDonald, Sharyn3; Crozier, Ian2

1. Yorkshire Heart Centre, Leeds General Infirmary, Leeds, United Kingdom; 2. Department of CardiacElectrophysiology, Christchurch Hospital, Christchurch, New Zealand; 3. Department of Radiology,Christchurch Hospital, Christchurch, New Zealand

75

156

REVASCULARISATION FOR ISCHAEMIC MYOCARDIAL DYSFUNCTION LEADING TO AN IMPROVEMENT IN EJECTION FRACTION IS NOT ASSOCIATED WITH AN INCREASE IN LONG AXIS TISSUE DOPPLER VELOCITY

Khan, SN; Heck, PM; Hoole, SP; Dutka, DP

Addenbrooke’s Hospital, Cambridge, United Kingdom

157

MYOFIBRILLAR EDEMA CAUSES POST-ISCHEMIC MYOCARDIAL DYSFUNCTION

Bragadeesh, T1; Jayaweera, R2; Le, E2; Kramer, CM3; Epstein, F3; Kaul, S2

1. Castle Hill Hospital, Kingston-Upon-Hull, United Kingdom; 2. Oregon Health Sciences University, Portland,United States; 3. University of Virginia, Charlottesville, United States


Lomond 16.00-17.00British Cardiovascular Society (BCS)Royal College of Physicians (RCP)

British Cardiovascular Society Lecture supported by the Joy Edelman Legacy

Managing heart failure in the future: the shape of things to comeProf John Cleland

Introduced by Prof David Crossman; Thanked by Prof Ian Gilmour

Lomond 17.00-18.30British Cardiovascular Society AGM

(Members only)

BCS Annual Dinner 20.00Kelvingrove Art Gallery

(Tickets only)

CP

D a

nd r

esea

rch

day

Wed

nesd

ay 6

Jun

e


Programme

74

151

DETERMINANTS OF PROGRESSION OF CORONARY ARTERY CALCIFICATION IN TYPE 2 DIABETES

Anand, D Vijay1; Lim, Eric1; Hopkins, David2; Darko, Daniel3; Lipkin, David1; Corder, Roger4; Lahiri, Avijit1

1. Cardiac Imaging and Research Centre, Wellington Hospital, London, United Kingdom; 2. Kings College Hospital, London, United Kingdom; 3. Central Middlesex Hospital, London, United Kingdom; 4. William Harvey Research Institute, London, United Kingdom

152

CORONARY CALCIFICATION IN TYPE II DIABETES PATIENTS IS ASSOCIATED WITH AN INCREASED RISK OF MYOCARDIAL ISCHAEMIA COMPARED TO NON-DIABETIC PATIENTS

Lim, ETS1; Ghani, F1; Jain, P1; Anand, DV1; Kooner, JS2; Lahiri, A1

1. Cardiac Imaging Dept, Wellington Hospital, London, United Kingdom; 2. Ealing Hospital, London, United Kingdom

153

PREDICTORS OF PROGRESSION OF CORONARY ARTERY CALCIUM IN TYPE 2 DIABETES: THE PREDICT STUDY

Flather, MD1; Rubens, M1; Godsland, IF2; Feher, MD3; Nugara, F1; Richmond, W2; Elkeles, RS2

1. Royal Brompton Hospital, London, United Kingdom; 2. Imperial College London and St Mary’s Hospital,London, United Kingdom; 3. Chelsea and Westminster Hospital, London, United Kingdom

154

EFFECTS OF OFF-PUMP VERSUS ON-PUMP CORONARY ARTERY BYPASS SURGERYON EARLY AND LATE RIGHT VENTRICULAR FUNCTION AS ASSESSED BY CARDIACMAGNETIC RESONANCE IMAGING

Pegg, TJ; Selvanayagam, JB; Karamitsos, TK; Arnold, JR; Neubauer, SN; Taggart, David

University of Oxford, Oxford, United Kingdom

155

EFFECTIVE RADIATION DOSE IN ANGIOGRAPHY OF CORONARY ARTERY BYPASSGRAFTS USING MULTISLICE COMPUTED TOMOGRAPHY

Smith, DK1; Negus, IS2; Hamilton, MCK2; Baumbach, A3

1. Gloucestershire Royal Hospital NHS Trust, Gloucester, United Kingdom; 2. Bristol Royal Infirmary, Bristol, United Kingdom; 3. Bristol Heart Institute, Bristol, United Kingdom

7776

Lomond Hall 1 Alsh Boisdale8.30

10.00

11.00

12.30

13.30

SCTSWhen is the patient too sick

for cardiac surgery?

National CardiovascularAudits – interim results

DebateDiagnostic coronary angiography

EPPacemakers and devices(158-164)

EPPacemakers and devices(220-228)

Audit, guidelinesand epidemiology

(165-173)

Audit, guidelinesand epidemiology

(229-237)

Echocardiography(183-191)

BSE/BCCA/SCTSAortic valve repair

C l o s e

M o d e r a t e d p o s t e r s i n e x h i b i t i o n ( 2 0 8 - 2 1 9 )


Carron Dochart 1 Dochart 2 Leven

Interventional cardiology(174-182)

Interventional cardiology(238-246)

Genetic and serummarkers of disease

(192-200)

Nuclear, MRI and CT

(247-255)

Vascular biology(256-264)

Hypertension, pulmonaryhypertension and CV

pharmacology(201-207)

Hypertension, pulmonaryhypertension and CV

pharmacology(265-273)

C l o s e

M o d e r a t e d p o s t e r s i n e x h i b i t i o n ( 2 0 8 - 2 1 9 )


CPD and research day Thursday 7 June

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


79

161

A STUDY OF THE EFFECTIVENESS OF PUBLIC ACCESS DEFIBRILLATION IN URBANAND RURAL POPULATIONS IN NORTHERN IRELAND: THE NORTHERN IRELANDPUBLIC ACCESS DEFIBRILLATION (NIPAD) STUDY

Moore, MJ1; Hamilton, AJ1; Cairns, KJ2; Glover, BM1; Ferguson, P1; Gray, D3; Marshall, AH2; Adgey, AAJ1; Kee, F3

1. Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, United Kingdom; 2. Department of Applied Mathematics, Queen’s University, Belfast, United Kingdom; 3. Department of Epidemiology and Public Health, Queen’s University, Belfast, United Kingdom

162

PREVALENCE AND SIGNIFICANCE OF AN ISOLATED LONG QTC INTERVAL ON 12-LEAD ECG IN ELITE ATHLETES

Basavarajaiah, S1; Wilson, M2; Chlebinska, A2; Shah, A1; Sharma, S1

1. King’s College Hospital, London, United Kingdom; 2. University Hospital Lewisham, London, United Kingdom

163

ICD SHOCKS: APPROPRIATE VERSUS INAPPROPRIATE IN MADIT II PATIENTS

Lin, G; Brady, PA

Mayo Clinic, Rochester, MN, United States

164

IMPROVED SAFETY OF COMPLEX DEVICE IMPLANTATION CAN BE ACHIEVED USING SIMPLE RADIATION DOSE REDUCTION MANOEUVRES

Rogers, DP; England, F; Dhinoja, M; Simon, R; Lowe, MD; Lambiase, PD; Chow, AW

The Heart Hospital, London, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

78


Lomond 08.30-10.00Society for Cardiothoracic Surgery (SCTS)

When is the patient too sick for cardiac surgery?

Chair: Mr Abdallah Al-Mohammad and Prof John Pepper

Coronary artery bypassMr Graham Cooper

Valve surgeryProf Sir Bruce Keogh

TransplantationMr Andrew Murday

Alsh 08.30-10.00Abstracts

EP pacemakers and devices

Chair: Dr Michael Gammage and Dr Derek Connelly

State of the art: Selection of patients for AICDProf Stuart Cobbe

158

WHAT RISK OF DEATH WOULD YOU ACCEPT BEFORE HAVING AN ICD?

Garratt, CJ

Manchester Heart Centre, Manchester, United Kingdom

159

INFLUENCE OF GENETIC TESTING ON IMPLANTATION OF ICDS IN PATIENTS WITHSUSPECTED ION CHANNELOPATHIES

Collitt, S1; Kerzin-Starr, L1; Moreton, N1; Metcalfe, K1; Newman, W1; Garratt, CJ2

1. Regional Genetic Service, Manchester, United Kingdom; 2. Manchester Heart Centre, Manchester, United Kingdom

160

THE USE OF AMIODARONE IN IMPLANTABLE CARDIAC DEFIBRILLATOR PATIENTS

Sandilands, AJ; Cripps, TR


81

170

INDISCRIMINATE USE OF TROPONIN I IN UNSELECTED MEDICAL EMERGENCIES

Nisbet, AM1; Dunn, FG2

1. BHF Glasgow Cardiovascular Research Centre, Glasgow, United Kingdom; 2. Stobhill Hospital, Glasgow, United Kingdom

171

NEED FOR CABG FOLLOWING PCI: A SINGLE CENTRE UK AUDIT OF 2,395 REVASCULARISATION PROCEDURES

Milborrow, GA; Child, NM; Purcell, IF

Freeman Hospital, Newcastle Upon Tyne, United Kingdom

172

INTRODUCTION OF INTEGRATED NURSE SPECIALIST LED MANAGMENT OF ACUTECORONARY SYNDROME PATIENTS – AN AUDIT

Alfakih, K; Melville, M; Nainby, J; Waterall, J; Walsh, J; Harcombe, A

QMC, Nottingham, United Kingdom

173

CLINICAL PRE-TEST PROBABILITY IS SUPERIOR TO EXERCISE-TESTING AS A TOOLFOR IDENTIFYING THE HIGHEST RISK PATIENTS: DATA FROM A RAPID ACCESSCHEST PAIN CLINIC

Thakaran, G; Deane, J; Tenkorang, J; Rakhit, R

Royal Free Hospital, London, United Kingdom



Chair: Dr Daniel Blackman and Dr Anthony Gershlick

174

OUTCOME OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN THE VERY ELDERLY

Crean, AM; Dorsch, M; Somers, K; Hague, C; McLenachan, JM; Blaxill, JM; Wheatcroft, SB; Mackintosh, AF; Greenwood, JP; Blackman, DJ

Leeds General Infirmary, Leeds, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

80



Chair: Dr Martyn Thomas and Dr Nicholas West

165

AN AUDIT OF HIGH DOSE VS STANDARD DOSE LIPID LOWERING THERAPYFOLLOWING ACUTE MYOCARDIAL INFARCTION: THE PATIENT COSTS RESULTINGFROM A FINANCIALLY MOTIVATED DRUG CHANGE IN NORTH STAFFORDSHIRE

Butler, R1; Wainwright, James2

1. University Hospital of North Staffordshire, Stoke on Trent, United Kingdom; 2. Keele University Medical School, Stoke on Trent, United Kingdom

166

A ONE YEAR EXPERIENCE OF PRIMARY PCI IN LEEDS: AN AUDIT OF PATIENTSEXCLUDED FROM INTERVENTIONAL THERAPY

Jani, M1; Lister, M1; Priestly, C1; Blackman, D2; Greenwood, JP2; McLenchan, JM2; Blaxill, JM1

1. St James University Hospital, Leeds, United Kingdom; 2. The General Infirmary at Leeds, Leeds, United Kingdom

167

DRUG ELUTING STENTS ARE NOT ASSOCIATED WITH AN INCREASE IN ALL CAUSE MORTALITY: RESULTS FROM A SINGLE TERTIARY CENTREFOLLOWING NICE GUIDELINES

Balachandran, KP; Singh, B; Edmond, JJ; Finch, D; Baumbach, A


168

SAFETY AND UTILITY OF ZERO AND SIX HOUR POINT OF CARE TROPONIN TESTINGIN LOW RISK POSSIBLE ACUTE CORONARY SYNDROMES – A DISTRICT GENERALHOSPITAL EXPERIENCE

Ray, G; Gaffney, T; Hood, S; Macintrye, P; Morgan, M; Russell, S; Findlay, I

Royal Alexandra Hospital, Paisley, United Kingdom

169

ASSESSMENT OF STANDARDS OF PERCUTANOUS INTERVENTIONAL PRACTICE –DEVELOPMENT OF A NETWORK-WIDE PEER REVIEW AUDIT PROCESS

Blows, LJH1; Dixon, G1; de Belder, A2

1. Sussex Cardiac Centre, Brighton, United Kingdom; 2. Sussex Cardiac Network, Brighton, United Kingdom

83

180

IMPACT OF PERIPROCEDURAL CREATINE KINASE-MB ISOENZYME ELEVATION ONLONG TERM MORTALITY AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI)

Andron, M; Egred, M; Alahmar, A; Shaw, M; Grayson, T; Roberts, E; Perry, R; Palmer, N

Cardiothoracic Centre, Liverpool, United Kingdom

181

DO PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION STILLREQUIRE CONSENTING FOR EMERGENCY CORONARY BYPASS SURGERY?

Arnold, JR; Shirodaria, C; Karamitsos, TD; van Gaal, WJ; Forfar, JC; Ormerod, OJM; Channon, KM; Westaby, S; Banning, AP

John Radcliffe Hospital, Oxford, United Kingdom

182

THE EFFECT OF REGIONAL WALL MOTION ABNORMALITIES ON CORONARYHAEMODYNAMICS

Hadjiloizou, N; Davies, J; Francis, D; Malik, I; Manisty, C; Foale, R; Parker, K; Hughes, A; Mayet, J

International Centre for Circulatory Health, St Mary’s Hospital, London, United Kingdom

Hall 1 08.30-10.00Abstracts

Echocardiography

Chair: Dr Guy Lloyd and Dr Simon Ray

183

IMPAIRED LEFT VENTRICULAR LONG AXIS FUNCTION IN MARFAN SYNDROMEDEMONSTRATED BY ABNORMAL MITRAL ANNULAR DISPLACEMENT

Kiotsekoglou, A1; Bajpai, A1; Karastergiou, K1; Athanasopoulos, G2; Moggridge, J1; Bijnens, B1; Nassiri, D1; Camm, AJ1; Sutherland, GR1; Child, A1

1. St George’s University of London, London, United Kingdom; 2. Onassis Cardiac Surgery Centre, Athens, Greece

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

82

175

SHOULD PATIENTS IN CARDIOGENIC SHOCK UNDERGO RESCUE ANGIOPLASTYAFTER FAILED FIBRINOLYSIS? COMPARISON OF PRIMARY VS. RESCUEANGIOPLASTY IN CARDIOGENIC SHOCK PATIENTS

Kunadian, B; Thornley, AR; Vijayalakshmi, K; Sutton, AGC; Muir, DF; Wright, RA; Hall, JA; de Belder, MA

The James Cook University Hospital, Middlesbrough, United Kingdom

176

RESCUE ANGIOPLASTY AFTER FAILED FIBRINOLYSIS FOR ACUTE MYOCARDIALINFARCTION: PREDICTORS OF A FAILED PROCEDURE AND ONE YEAR MORTALITY

Kunadian, B; Thornley, R; Vijayalakshmi, K; Dunning, J; Sutton, AGC; Muir, DF; Wright, RA; Hall, JA; de Belder, MA


177

REDUCED VASCULAR COMPLICATIONS AND LENGTH OF STAY WITH TRANSRADIALRESCUE ANGIOPLASTY FOR ACUTE MYOCARDIAL INFARCTION

Cruden, NL1; Huat, CT2; Starkey, IR1; Newby, DE2

1. Western General Hospital, Edinburgh, United Kingdom; 2. University of Edinburgh, Edinburgh, United Kingdom

178

EVALUATION OF SAFETY AND EFFICACY OF ANGIOJET USAGE IN A UK HEARTATTACK CENTRE

Strange, JW; Cheng, Z; Critoph, CJ; Archbold, SA; Rothman, MT

The London Chest Hospital, London, United Kingdom

179

EFFECT OF DISTAL EMBOLISATION ON MYOCARDIAL PERFUSION RESERVEFOLLOWING PERCUTANEOUS CORONARY INTERVENTION: AN QUANTITATIVE MR PERFUSION STUDY

Selvanayagam, JB1; Cheng, ASH1; Rahimi, K1; Porto, I2; Van Gaal, William2; Channon, K1; Neubauer, S1; Banning, AP2

1. University of Oxford, Oxford, United Kingdom; 2. John Radcliffe Hospital, Oxford, United Kingdom

85

189

TRANSTHORACIC ECHOCARDIOGRAPHY PRACTICE IN THE UNITED KINGDOM

MacDonald, MR1; Hawkins, NM1; Balmain, S2; McMurray, JJV3; Petrie, MC1

1. Glasgow Royal Infirmary, Glasgow, United Kingdom; 2. Western Infirmary of Edinburgh, Edinburgh, United Kingdom; 3. Western Infirmary, Glasgow, United Kingdom

190

PATENT FORAMEN OVALE – AN EVALUATION OF DIFFERENT DIAGNOSTICTECHNIQUES AND ROUTES OF CONTRAST ADMINISTRATION

Velupandian, UM1; Khiani, R1; Ray, SG2; Calderwood, R1; Herring, E1; Bonner, Z1; Heagerty, AM1; Morris, J2; McCollum, CN1

1. University of Manchester, Manchester, United Kingdom; 2. South Manchester University Hospital, Manchester, United Kingdom

191

ASSESSMENT OF MYOCARDIAL PERFUSION – CAN IT BE DONE USING REAL TIME 3D ECHO?

Bhan, A; Kapetanakis, S; Rana, BS; Ho, E; Wilson, K; Monaghan, MJ

King’s College Hospital, London, United Kingdom

Dochart 1 08.30-10.00Abstracts

Genetic and serum markers of disease

Chair: Prof Bernard Keavney and Dr Kosh Ray

192

HERITABILITY OF THE QTC INTERVAL: ANALYSIS IN A POPULATION BASED FAMILY STUDY

Hajat, C1; Gracey, J2; Smith, T2; MacFarlane, PW3; Ng, A2; Burton, PR1; Tobin, MD1; Samani, NJ2

1. Dept of Health Sciences and Dept of Genetics, University of Leicester, Leicester, United Kingdom; 2. Dept of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; 3. Medical Sciences, University of Glasgow, Glasgow, United Kingdom

193

ASSOCIATION BETWEEN POLYMORPHIC VARIATION IN THE ENDOTHELIN-1 TYPE A RECEPTOR GENE (EDNRA) AND AMBULATORY BLOOD PRESSURE

Rahman, T; Hall, DH; Avery, PJ; Keavney, B

Newcastle University, Newcastle upon Tyne, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

84

184

DIFFERENTIATION BETWEEN HYPERTROPHIC CARDIOMYOPATHY ANDHYPERTENSIVE LEFT VENTRICULAR HYPERTROPHY: THE ROLE OF STRAIN RATEIMAGING STUDY AND INTEGRATED BACKSCATTER ANALYSIS

Orlando, S; Puntmann, V; Baltabaeva, A; Marciniak, M; Marciniak, A; Karu, T; Bijnens, B; Sutherland, GR

St George’s Hospital, London, United Kingdom

185

MYOCARDIAL DEFORMATION IMAGING FOR THE PREDICTION OF SUBCLINICALLEFT VENTRICUALAR DYSFUNCTION AND MORTALITY IN ASYMPTOMATIC PATIENTS WITH END STAGE RENAL DISEASE AND NORMAL LEFT VENTRICULAREJECTION FRACTION

Sharma, R1; Pellerin, D2; Gregson, H3; Streather, C3; Gaze, D3; Collinson, PO4; Brecker, SJD3

1. Ealing Hospital, London, United Kingdom; 2. The Heart Hospital, London, United Kingdom; 3. St Georges Hospital, London, United Kingdom; 4. St Georges Hospital, London, United Kingdom

186

THE EXTENT OF RESIDUAL CONTRAST PERFUSION AND NOT LEFT VENTRICULARFUNCTION PREDICTS LATE RECOVERY OF GLOBAL CONTRACTILE FUNCTIONAFTER ACUTE MYOCARDIAL INFARCTION AND REPERFUSION THERAPY

Dwivedi, G; Janardhanan, R; Swinburn, J; Greaves, K; Senior, R


187

ABNORMAL LEFT VENTRICULAR TORSION IN CHRONIC MITRAL REGURGITATION: A SPECKLE TRACKING ECHOCARDIOGRAPHY STUDY

Borg, AN; Harrison, JL; Laws, CD; Fox, DJ; Khan, W; Ray, SG

Department of Cardiology, Wythenshawe Hospital, Manchester, United Kingdom

188

INDEPENDENT VALUE OF LEFT ATRIAL VOLUME INDEX FOR THE PREDICTION OF ALL CAUSE MORTALITY IN PATIENTS WITH SUSPECTED HEART FAILUREREFERRED FROM THE COMMUNITY

Lim, TK; Dwivedi, G; Hayat, SA; Senior, R

Northwick Park Hospital, Cardiovascular Medicine, Harrow, United Kingdom

87

199

SERUM METABOLOMIC ANALYSIS SUCESSFULLY DISCRIMINATES HEART FAILUREPATIENTS FROM CONTROLS

Deepak, SM1; Dunn, WB2; Broadhurst, DI2; Buch, MH3; McDowell, G4; Ellis, DI2; Brooks, NH1; Kell, DB5; Neyses, L3

1. South Manchester University Hospitals NHS Foundation Trust, Wythenshawe Hospital, Manchester, United Kingdom; 2. School of Chemistry and The Manchester Centre for Integrative Systems Biology, The University of Manchester, Manchester, United Kingdom; 3. Division of Cardiovascular and EndocrineSciences, The University of Manchester, Manchester, United Kingdom; 4. Department of Clinical Biochemistry,Manchester Royal Infirmary, Manchester, United Kingdom; 5. School of Chemistry and The Manchester Centre for Integrative Systems Biology, The University of Manchester, Manchester, United Kingdom

200

A NOVEL SCORE BASED ON AGE AND CARDIAC BIOMARKERS PREDICTSOUTCOMES IN SEVERE SEPSIS AND SEPTIC SHOCK

Turley, AJ; Thornley, AR; Kunadian, B; Roberts, AP; Johnson, M; Gedney, J; de Belder, MA



Hypertension, pulmonary hypertension and CV pharmacology

Chair: Dr Richard Bogle and Dr Adrian Brady

State of the art: New ways of assessing blood pressureProf John Cockcroft

201

A UNIFYING EXPLANATION OF THE ARTERIAL PULSE WAVEFORM IN HUMANS AND THE IMPLICATIONS FOR CENTRAL BLOOD PRESSURE AUGMENTATION

Davies, JE1; Hadjiloizou, N1; Manisty, CH1; Whinnett, ZI1; Foale, RA1; Malik, IS1; Hughes, AD1; Parker, KH1; Darrel, DP2; Mayet, J2

1. International Centre for Circulatory Health, St Mary’s Hospital and Imperial College, London, United Kingdom; 2. International Centre for Circulatory Health, St Mary’s Hospital & Imperial College, London, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

86

194

LEUKOTRIENE B4 PRODUCTION IN SUBJECTS WITH VARIANTS OF THE 5-LIPOXYGENASE ACTIVATING PROTEIN GENE ASSOCIATED WITH RISK OF MYOCARDIAL INFARCTION

Maznyczka, A1; Mangino, M1; Whittaker, A1; Braund, P1; Palmer, T2; Tobin, M2; Goodall, A1; Bradding, P3; Samani, NJ1

1. Dept of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; 2. Dept of HealthSciences, University of Leicester, Leicester, United Kingdom; 3. Dept of Infection, Inflammation & Immunity,University of Leicester, Leicester, United Kingdom

195

CHARACTERISATION OF MICRORNAS IN THE HUMAN HEART

Lu, H1; Punjabi, PP2; Rahman, F1; Camici, PG1; Aitman, TJ1; Cook, SA1

1. Clincial Sciences Centre, MRC, London, United Kingdom; 2. Hammersmith Hospital, London, UnitedKingdom

196

PLASMA BRAIN NATRIURETIC PEPTIDE PREDICTS OUTCOME IN PATIENTS WITH FRACTURED NECK OF FEMUR

Descamps, MJL1; Ryding, ADS1; Jeilan, M1; Bankart, J2; Crawfurd, EJP1; Gidden, DJ1; Sprigings, DC1

1. Northampton General Hospital, Northampton, United Kingdom; 2. Department of Health Sciences,University of Leicester, Leicester, United Kingdom

197

HEART-TYPE FATTY ACID BINDING PROTEIN (H-FABP) PREDICTS MORTALITY INPATIENTS WITH SINUS RHYTHM AND LEFT VENTRICULAR SYSTOLIC DYSFUNCTION

Loh, PH1; Tin, L1; Windram, JD1; Reddy, P1; Khaleva, O1; Mathur, G1; Nicholls, R1; Goode, K1; Nikitin, NP1; Stanton, EB2; Clark, AL1; Cleland, JGF1

1. Academic Cardiology Dept., University of Hull, Hull, United Kingdom; 2. McMaster University, Ontario, Canada

198

NT-PROBNP AS A BIOMARKER FOR THE DEVELOPMENT OF CARCINOID HEART DISEASE


1. Department of Cardiology, Royal Free Hospital, London, United Kingdom; 2. Neuroendocrine Tumour Unit, Royal Free Hospital, London, United Kingdom

89

206

CHARACTERISATION OF THE VASODILATORY ACTION OF 17ß OESTRADIOL IN THEHUMAN PULMONARY CIRCULATION

Smith, AM1; Sandher, RK2; Bennett, RT3; Jones, TH4; Jones, RD2; Cowen, ME3; Channer, KS1

1. Royal Hallamshire Hospital, Sheffield, United Kingdom; 2. University of Sheffield, Sheffield, United Kingdom; 3. Castle Hill Hospital, Cottingham, United Kingdom; 4. Barnsley District General Hospital, Barnsley, United Kingdom

207

VITAMIN D IMPROVES MARKERS OF VASCULAR HEALTH IN PATIENTS WITH TYPE 2 DIABETES

Sugden, JA1; Davies, JI2; Witham, MD1; Morris, AD1; Struthers, AD1

1. University of Dundee, Dundee, United Kingdom; 2. Universtiy of Dundee, Dundee, United Kingdom


Basic science

Chair: Prof Shoumo Bhattacharya and Prof Roberto Ferrari

208

C-TERMINAL ProVASOPRESSIN (COPEPTIN) PREDICTS RISK OF DEATH OR HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION. THE LEICESTER ACUTE MYOCARDIAL INFARCTION PEPTIDE (LAMP) STUDY

Khan, SQ1; O’Brien, R1; Struck, J2; Quinn, PA1; Dhillon, OS1; Morgenthaler, N2; Squire, I1; Davies, J1; Bergmann, A2; Ng, LL1

1. University of Leicester, Leicester, United Kingdom; 2. BRAHMS AG, Hennigsdorf/Berlin, Germany

209

KNOCKDOWN IN ZEBRAFISH SUPPORTS IMPORTANT ROLE FOR MYOCYTE STRESS (MS1) IN CARDIAC DEVELOPMENT AND FUNCTION

Mahadeva, H1; Mason, A1; Chong, N1; Shaw, SY2; Samani, NJ1

1. Dept of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; 2. Research Center,Massachusetts General Hospital, Massachusetts, United States

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

88

202

THE C-532T POLYMORPHISM OF THE ANGIOTENSINOGEN (AGT) GENE IS ASSOCIATED WITH ARTERIAL STIFFNESS: A POSSIBLE EXPLANATION FOR HETEROGENEITY IN GENETIC ASSOCIATION STUDIES OF AGT AND HYPERTENSION

Rahman, T1; Baker, ML1; Hall, DH1; Avery, PJ1; Mayosi, BM2; Connell, JMC3; Farrall, M4; Watkins, H4; Keavney, B1

1. Newcastle University, Newcastle upon Tyne, United Kingdom; 2. University of Cape Town, Cape Town, South Africa; 3. University of Glasgow, Glasgow, United Kingdom; 4. University of Oxford, Oxford, United Kingdom

203

DIFFERENCES IN THE MAGNITUDE RATHER THAN THE TIMING OF WAVEREFLECTION CAN EXPLAIN THE ASCOT RESULTS

Manisty, CH1; Davies, JE1; Whinnett, ZI1; Francis, DP1; Zambanini, A1; Zambanini, A1; Curtis, S1; Thom, S. McG1; Hughes, AD2; Mayet, J1

1. International Centre for Circulatory Health, Imperial College and St. Mary’s Hospital, London, United Kingdom; 2. International Centre for Circulatory Health and Imperial College, London, United Kingdom

204

EFFECTS OF INHIBITION OF NITRIC OXIDE SYNTHASE ON SYSTOLIC PRESSUREAUGMENTATION AND CONDUIT ARTERY DIAMETER

Munir, SM1; Jiang, B1; Guilcher, A1; Brett, S1; Redwood, S2; Chowienczyk, P1

1. Cardiovascular Division Kings College London, London, United Kingdom; 2. St Thomas’ Hospital, London, United Kingdom

205

ASSOCIATION BETWEEN ALDOSTERONE PRODUCTION AND VARIATION IN THE GENE ENCODING 11-BETA HYDROXYLASE (CYP11B1)

Imrie, H1; Freel, M2; Mayosi, BM3; Davies, E2; Fraser, R2; Ingram, M2; Cordell, HJ1; Avery, PJ1; Farrall, M4; Watkins, H4; Connell, JMC2; Keavney, B1

1. Newcastle University, Newcastle upon Tyne, United Kingdom; 2. University of Glasgow, Glasgow, United Kingdom; 3. University of Cape Town, Cape Town, South Africa; 4. University of Oxford, Oxford, United Kingdom

91

215

SUDDEN ARRHYTHMIC DEATH SYNDROME-DIAGNOSTIC YIELD OF CLINICALSCREENING IN FAMILY MEMBERS AT THE HEART HOSPITAL, UCL 2003-2006

Lambiase, PD1; Kaski, JC1; Firman, E1; Elliott, PM1; Ahmed, AK1; Chow, AW1; Hughes, S2; Sheppard, MN3; Lowe, MD1; McKenna, WJ4

1. Heart Hospital, UCL, London, United Kingdom; 2. UCL, London, United Kingdom; 3. Royal BromptonHospital, London, United Kingdom; 4. Heart Hospital,UCL, London, United Kingdom

216

ELECTROPHYSIOLOGIC AND ANATOMIC CHARACTERISATION OF SITES RESISTANTTO ELECTRICAL ISOLATION DURING CIRCUMFERENTIAL PULMONARY VEINABLATION FOR ATRIAL FIBRILLATION: A PROSPECTIVE STUDY

Kistler, P1; Rajappan, K1; Yen Ho, S2; Morpher, M1; Harris, S1; Abrams, D1; Gupta, D1; Sporton, SC1; Schilling, RJ1

1. The Department of Cardiology, St Bartholomew’s Hospital and Queen Mary University, London, United Kingdom; 2. National Heart and Lung Institute, Imperial College, London, United Kingdom

217

RECOGNITION OF ECG ABNORMALITIES ASSOCIATED WITH ATRIOVENTRICULARCONDUCTION DEFECTS

McComb, JM; Plummer, CJ


218

LONG-TERM EFFECTS OF CARDIAC RESYNCHRONISATION THERAPY IN PATIENTSWITH CHRONIC ATRIAL FIBRILLATION

Chalil, S; Khadjooi, K; Muhyaldeen, S; Smith, REA; Leyva, F

Good Hope Hospital, Sutton Coldfield, United Kingdom

219

LONG TERM SURVIVAL OF PATIENTS WITH A NEW DIAGNOSIS OF HEART FAILURE: A POPULATION BASED PROSPECTIVE COHORT STUDY

Roughton, Michael1; Mannan, I2; Sutton, GC3; Wood, D3; Fox, K4; Cowie, MR3

1. Royal Brompton & Harefield NHS Trust, London, United Kingdom; 2. Faculty of Medicine, Imperial College, London, United Kingdom; 3. National Heart & Lung Institute, Imperial College, London, United Kingdom; 4. Charing Cross Hospital, London, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

90

210

EXPRESSION OF MYOCYTE STRESS 1 (MS1), A NOVEL GENE INVOLVED IN CARDIACDEVELOPMENT AND HYPERTROPHY IS REGULATED BY EVOLUTIONARILYCONSERVED GATA MOTIFS

Ounzain, S1; Peterson, RE2; Menick, DR2; Samani, NJ1; Chong, NW1

1. University of Leicester, Leicester, United Kingdom; 2. Gazes Cardiac Research Institute, South Carolina,United States

211

HETEROZYGOUS CARRIAGE OF THE KLOTHO KL-VS ALLELE IS ASSOCIATED WITH REDUCED RISK OF MYOCARDIAL INFARCTION

Whittaker, A1; Hetherington, SL1; Brouilette, S1; Singh, RK1; Thompson, JR2; Steeds, R3; Channer, K3; Samani, NJ1

1. Dept of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; 2. Dept of HealthSciences, University of Leicester, Leicester, United Kingdom; 3. Royal Hallamshire Hospital, Sheffield, United Kingdom

212

APELIN EXHIBITS CARDIOPROTECTION AGAINST ISCHAEMIA REPERFUSION INJURY

Simpkin, JC; Yellon, DM; Davidson, SM; Lim, SY; Wynne, AM; Smith, CCT

The Hatter Cardiovascular Institute, University College Hospital and Medical School, London, United Kingdom

213

HYPOXIC AND PHARMACOLGICAL POSTCONDITIONING PROTECTS THE HUMANHEART BY ACTIVATING PHOSPHATIDYLINOSITOL-3-KINASE

Mudalagiri, NR; Hausenloy, DJ; Yellon, DM

The Hatter Cardiovascular Institute, UCL, London, United Kingdom


Clinical science

Chair: Dr Jonathan Sahu and Dr Edward Rowland

214

IMPROVEMENT IN VASCULAR FUNCTION WITH LOW-DOSE FOLIC ACIDSUPPLEMENTATION: IMPLICATIONS FOR FOLATE THERAPY AND DIETARYFORTIFICATION

Shirodaria, C; Antoniades, C; Lee, J; Jackson, CE; Francis, JM; Robson, MD; Ratnatunga, C; Pillai, R; Neubauer, S; Channon, KM

University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

93

Alsh 11.00-12.30Abstracts

EP pacemakers and devices

Chair: Dr Prapa Kanagaratnam and Dr Adrian Rozkovec

220

INTRAVENTRICULAR DYSSYNCHRONY PREDICTS MORTALITY AND MORBIDITYFOLLOWING CARDIAC RESYNCHRONISATION THERAPY: A STUDY USINGCARDIOVASCULAR MAGNETIC RESONANCE TISSUE SYNCHRONISATION IMAGING

Chalil, S1; Stegemann, B2; Muhyaldeen, S1; Khadjooi, K1; Sandman, Harald1; Smith, REA1; Leyva, F1

1. Good Hope Hospital, Sutton Coldfield, United Kingdom; 2. Medtronic Inc, Maastricht, Netherlands

221

ECHOCARDIOGRAPHIC OPTIMISATION OF INTER-VENTRICULAR DELAY IMPROVESEXERCISE PERFORMANCE COMPARED TO SIMULTANEOUS BIVENTRICULAR PACING

Fox, DJ1; Khattar, RS2; Fitzpatrick, AP2; Borg, AN1; Clayton, NJ1; Beynon, RP1; Williams, SG1; Khan, W1; Shaw, SM1; Roberts, SA2; Davidson, NC1

1. North West Regional Cardiac Centre, Wythenshawe Hospital, Manchester, United Kingdom; 2. Manchester Heart Centre, Manchester Royal Infirmary, Manchester, United Kingdom

222

LONG TERM LEFT VENTRICULAR LEAD STABILITY DURING BIVENTRICULAR PACING

Willis, J; Thomas, DE; Webb, G; Penny, A; O’Callaghan, P; Anderson, RA; Yousef, Z

University Hospital of Wales, Cardiff, United Kingdom

223

EFFECT OF POSTEROLATERAL LEFT VENTRICULAR SCAR ON MORTALITY ANDMORBIDITY FOLLOWING CARDIAC RESYNCHRONISATION THERAPY: A LATEGADOLINIUM ENHANCEMENT CARDIOVASCULAR MAGNETIC RESONANCE STUDY

Chalil, S1; Muhyaldeen, S1; Khadjooi, K1; Smith, REA1; Jordan, P1; Patel, K2; Leyva, F1

1. Good Hope Hospital, Sutton Coldfield, United Kingdom; 2. Sandwell and City Hospitals, Birmingham, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

92

Lomond 11.00-12.30National cardiovascular audits – interim results

Chair: Prof David Crossman and Prof Adam Timmis

Healthcare Commission – heart failure improvement reviewProf Martin Cowie and Ms Cate Quinn

National Infarct Angioplasty Project (NIAP)Dr Huon Gray

Death following a first time, isolated coronary artery bypass graft. Interim report – Year 2Ms Heather Cooper

The Scottish Coronary Revascularisation Register Dr Jill Pell

The secondary care perspective on the National Programme Dr Simon Eccles

Hall 1 11.00-12.30British Society of Echocardiology (BSE)British Congenital Cardiac Association (BCCA)Society for Cardiothoracic Surgery (SCTS)

Aortic valve repair

Chair: Mr Leslie Hamilton and Dr Alan Houston

Patterns of aortic valve diseaseDr Mark Turner

What the surgeon needs to know to select patientsDr Simon Ray

Aortic valve repair – the surgeon’s viewMr David Barron

Current outcomesDr Derek Chin

95



Chair: Dr Nikhil Patel and Dr Bernard Prendergast

229

RADIATION EXPOSURE AND PROCEDURAL DURATION: IMPLICATIONS FORTRANSRADIAL AND TRANSFEMORAL CORONARY ANGIOGRAPHY

Lo, TSN; Fountzopoulos, E; Freestone, B; Gunning, M; Nolan, J


230

ARE CARDIOLOGISTS IMMORTAL?

Yan, YM1; Patel, KCR2; Patel, KV3; Judge, P3; Patel, J3; Johal, S3; Do, P3

1. Sandwell Hospital, Birmingham, United Kingdom; 2. Sandwell Hospital and University of Birmingham, Birmingham, United Kingdom; 3. University of Birmingham, Birmingham, United Kingdom

231

A SIMPLE RISK MODEL FOR PREDICTING 30-DAY MORTALITY IN PATIENTSPRESENTING WITH ACUTE CORONARY SYNDROME

Das, R; Gale, C; Kilcullen, N; Morrell, C; Barth, JH; Hall, AS

BHF Heart Research Centre, Leeds, United Kingdom

232

LOWER MORTALITY IN ACUTE MYOCARDIAL INFARCTION WHERE THROMBOLYSISIS ADMINISTERED IN THE COMMUNITY

Tan, YT1; Mavroudis, C2; Khan, T2; Butler, R2; Nolan, J2; Gunning, MG2

1. University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom; 2. University Hospital of NorthStaffordshire, Stoke-on-Trent, United Kingdom

233

HYPERGLYCAEMIA, IN RELATION TO GENDER, AND MORTALITY AFTER ACUTECORONARY SYNDROME

Cubbon, RM1; Rajwani, A1; Grant, PJ1; Wheatcroft, SB1; Barth, JH2; Kearney, MT1; Hall, AS1

1. The University of Leeds, Leeds, United Kingdom; 2. Leeds General Infirmary, Leeds, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

94

224

AF MAY BEGET AF BUT DOES PAF BEGET PAF?

Silberbauer, J1; Veasey, RA1; Cheek, E2; Lloyd, GW1; Sulke, AN1

1. East Sussex Hospitals NHS Trust, Eastbourne, United Kingdom; 2. University of Brighton, Brighton, United Kingdom

225

ELECTROPHYSIOLOGICAL CHARACTERISTICS OF SYMPTOMATIC ATRIALFIBRILLATION

Veasey, RA1; Silberbauer, J1; Cheek, E2; Arya, A1; Sulke, AN1

1. East Sussex Hospitals NHS Trust, Eastbourne, United Kingdom; 2. University of Brighton, Brighton, United Kingdom

226

ALL CAUSE AND CARDIOVASCULAR MORTALITY RELATED TO LONGTERM RATE OR RHYTHM CONTROL STRATEGIES IN PATIENTS UNDERGOING SEDATION DCCARDIOVERSION FOR ATRIAL FIBRILLATION

Arya, A; Silberbauer, J; Vrahimides, J; Bordoli, G; Large, J; Lloyd, GW; Patel, NR; Sulke, AN

Eastbourne DGH, Eastbourne, United Kingdom

227

“MINVPACE”: A STUDY COMPARING MINIMAL VENTRICULAR PACING AND PREVENTIVE AF ALGORITHMS IN THE TREATMENT OF PAF

Arya, A1; Veasey, R1; Silberbauer, J1; Edwards, CP1; Lloyd, GW2; Patel, NR1; Sulke, AN1

1. Eastbourne DGH, Eastbourne, United Kingdom; 2. Eastbourne DGH, Eastbourne, United Kingdom

228

DELAYS TO PERMANENT PACEMAKER IMPLANTATION: AN EXPLANATION FOR LOWIMPLANTATION RATES IN THE UNITED KINGDOM?

Cunnington, MS; Plummer, CJ; McDiarmid, AK; McComb, JM


97

239

SIMULTANEOUS KISSING STENTS (SHOTGUN STENTS) TO TREAT LEFT MAINBIFURCATION STENOSIS

Siotia, A; Morton, A; Gunn, J

Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

240

TRANSCATHETER CLOSURE OF PARAVALVAR PROSTHETIC VALVE LEAKS USINGTHE AMPLATZER OCCLUDERS

DeGiovanni, JV1; Ludman, P2; Hildick-Smith, D3; Malik, I4; Khogali, S5; Been, M6

1. Birmingham Children’s Hospital, Birmingham, United Kingdom; 2. University Hospital Birmingham, Birmingham, United Kingdom; 3. Royal Sussex County Hospital, Brighton, United Kingdom; 4. St Mary’s Hospital, London, United Kingdom; 5. Heart and Lung Centre, Wolverhampton, United Kingdom; 6. Walsgrave Hospital, Coventry, United Kingdom

241

ASSOCIATION OF PLAQUE THICKNESS WITH ENDOTHELIAL SHEAR STRESS IN THE LEFT MAIN CORONARY ARTERY BIFURCATION: IN VIVO STUDY USING 3D RECONSTRUCTION AND COMPUTATIONAL FLUID DYNAMICS

Papafaklis, MI1; Bourantas, CV2; Theodorakis, .E3; Katsouras, CS4; Fotiadis, DI5; Michalis, LK4

1. Michaelideion Cardiac Centre, University of Ioannina, Ioannina, Greece; 2. Michaelideion Cardiac Center, University of Ioannina, Ioannina, Greece; 3. Department of Materials Science and Engineering, University of Ioannina, Ioannina, Greece; 4. Department of Cardiology, Medical School, University of Ioannina, Ioannina, Greece; 5. Department of Computer Science, University of Ioannina, Ioannina, Greece

242

RADIAL ARTERY DIAMETER, ITS RESPONSE TO SUBLINGUAL GTN AND IMPLICATIONFOR TRANSRADIAL CARDIAC CATHETERISATION

Lo, TSN; Nolan, J


243

THE RISK OF VENTRICULAR ARRHYTHMIA FOLLOWING ALCOHOL SEPTALABLATION (ASA) FOR HYPERTROPHIC CARDIOMYOPATHY (HCM) WITHSYMPTOMATIC LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION

Smith, EJ; Chen, Z; Shetty, A; Ang, R; Knight, CJ

London Chest Hospital, London, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

96

234

TEMPORAL TRENDS IN MORTALITY OF PATIENTS WITH DIABETES MELLITUSSUFFERING ACUTE MYOCARDIAL INFARCTION: A COMPARISON OF OVER 3000 PATIENTS BETWEEN 1995 AND 2003

Cubbon, RM1; Rajwani, A1; Wheatcroft, SB1; Grant, PJ1; Gale, CP2; Barth, JH2; Sapsford, RJ3; Kearney, MT1; Hall, AS1

1. The University of Leeds, Leeds, United Kingdom; 2. Leeds General Infirmary, Leeds, United Kingdom; 3. St. James University Hospital, Leeds, United Kingdom

235

RISK FACTORS IN PATIENTS WITH AN OUT-OF-HOSPITAL CARDIAC ARREST

Hamilton, AJ1; Moore , MJ1; Cairns, KJ2; Adgey, AAJ1; Kee, F3

1. Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, United Kingdom; 2. Department of Applied Mathematics, Queen’s University of Belfast, Belfast, United Kingdom; 3. Department of Epidemiology and Public Health, Queen’s University of Belfast, Belfast, United Kingdom

236

RAPID ACCESS CHEST PAIN CLINIC REFERRALS FOR ANGIOGRAPHY: ROOM FORIMPROVEMENT?

Tough, J; Thornley, AR; Turley, AJ; Kunadian, B; Morley, R; Stewart, MJ; de Belder, MA


237

AGE-RELATED CHANGES IN CAROTID ARTERY LUMEN AND WALL VOLUME IN A POPULATION FREE OF CARDIAC RISK FACTORS

Keenan, NG; Pennell, DJ

Royal Brompton Hospital, London, United Kingdom



Chair: Dr Dwayne Conway and Dr Kevin Jennings

238

STABILISATION OF CORONARY STENTS USING RAPID RIGHT VENTRICULAR PACING

O’Brien, DG; Smith, WH; Henderson, RA

Trent Cardiac Centre, Nottingham City Hospital, Nottingham, United Kingdom

99

248

UNCOMPLICATED OBESITY IS CHARACTERISED BY ALTERED SYSTOLIC ANDDIASTOLIC MYOCARDIAL VELOCITIES AS ASSESSED BY PHASE CONTRASTMAGNETIC RESONANCE IMAGING

Ali, MK1; Rider, OJ1; Petersen, SE1; Francis, JM1; Robson, MD1; Robson, MD1; Jackson, CE1; Jung, BA2; Robinson, MR1; Neubauer, S1

1. Oxford Centre for Magnetic Resonance Research, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom; 2. Department of Diagnostic Radiology, Medical Physics, University of Freiburg, Freiburg, Germany

249

TROPONIN-I CONCENTRATIONS 72 HOURS AFTER MYOCARDIAL INFARCTION ARE A RELIABLE PREDICTOR OF INFARCT SIZE AND MICROVASCULAR OBSTRUCTION – A CMR IMAGING STUDY

Younger, JF1; Plein, S1; Barth, J2; Sivananthan, M2; Ridgway, JP2; Ball, S1; Greenwood, JP1

1. Leeds University, Leeds, United Kingdom; 2. Leeds General Infirmary, Leeds, United Kingdom

250

SEVERITY OF CARCINOID HEART DISEASE AND RELATIONSHIP WITH NT-PROBNP


1. Department of Cardiology, Royal Free Hospital, London, United Kingdom; 2. Neuroendocrine Tumour Unit, Royal Free Hospital, London, United Kingdom

251

ECHOCARDIOGRAPHY FOR CARDIOMEGALY IDENTIFIED IN CHEST X-RAY – AN AUDIT OF 625 PATIENTS

Sulfi, S1; Balami, D1; Suliman, A1; Archbold, RA2; Kapur, A2; Ranjadayalan, K1; Timmis, AD2

1. Newham University Hospital, London, United Kingdom; 2. London Chest Hospital, London, United Kingdom

252

CT ATTENUATION CORRECTION OF SPECT MYOCARDIAL PERFUSIONSCINTIGRAPHY IMPROVES DIAGNOSTIC ACCURACY

Wright, GA; Cockburn, KC; Davies, G; Avery, GR; Tweddel, AC

Hull & East Yorkshire Hospitals NHS Trust, Cottingham, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

98

244

CORONARY COLLATERALS REMAIN RECRUITABLE FOLLOWING PERCUTANEOUSINTERVENTION

Perera, D; Kanaganayagam, GS; Saha, M; Rashid, R; Marber, MS; Redwood, SR

St Thomas’ Hospital Campus, Kings College London, London, United Kingdom;

245

COMPARISON BETWEEN PRESSURE DERIVED AND THERMODILUTION DERIVED FLOW RESERVE IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

Blows, LJH; Perera, SD; Behan, M; Marber, MM; Redwood, SR

St Thomas’ Hospital, London, United Kingdom

246

PRE-OPERATIVE NEUTROPHIL-LYMPHOCYTE RATIO AND OUTCOME FROMCORONARY ARTERY BYPASS GRAFTING

Gibson, PH; Croal, BL; Cuthbertson, BH; Small, GR; Ifezulike, AI; Gibson, G; Jeffrey, RR; Buchan, KG; El-Shafei, H; Hillis, GS

Aberdeen Royal Infirmary, Aberdeen, United Kingdom


Nuclear, MRI and CT

Chair: Dr John Greenwood and Dr Simon Woldman

247

THE PREVELENCE AND PROGNOSTIC VALUE OF ATHEROSCLEROTIC RENALARTREY STENOSIS IN PATIENTS WITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTION

Bourantas, CV1; Loh, PH1; Ettles, DF2; de Silva, R1; Lukaschuk, EI1; Tweddel, AC1; Clark, AL1; Nikitin, P1; Cleland, JGF1

1. Department of Academic Cardiology, Castle Hill Hospital, Cottingham, United Kingdom; 2. Department of Vascular Radiology, Hull Royal Infirmary, Hull, United Kingdom

101

257

DEVELOPMENT AND CHARACTERISATION OF VIRAL VECTORS TARGETED TO ATHEROSCLEROTIC PLAQUES

White, K1; Buening, H2; McVey, JH3; Murphy, G4; Work, LM1; Hallek, M2; Nicklin, SA1; Baker, AH1

1. BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom; 2. Clinic I for Internal Medicine and Center for Molecular Medicine, University of Cologne, Cologne, Germany; 3. Haemostasis and Thrombosis, MRC Clinical Sciences Centre, Imperial Collage London, London, United Kingdom; 4. Department of Oncology, Cambridge University, Cambridge Institute for Medical Research, Cambridge, United Kingdom

258

ELEVATED CIRCULATING ENDOTHELIAL PROGENITOR CELLS IN HEALTHY ADULTOFFSPRING OF SUBJECTS WITH CORONARY ARTERY DISEASE

Whittaker, A; Moore, JS; Vasa, M; Stevens, S; Samani, NJ

Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom

259

IGFBP-1 PROTECTS AGAINST OBESITY-INDUCED VASCULAR DYSFUNCTION BY PRESERVATION OF INSULIN SIGNALLING

Ezzat, VA1; Wheatcroft, SB2; Duncan, ER1; Sethi, JK3; Shah, AM1; Kearney, MT2

1. King’s College London, London, United Kingdom; 2. University of Leeds, Leeds, United Kingdom; 3. University of Cambridge, Cambridge, United Kingdom

260

PRESENCE OF ATHEROSCLEROSIS DETERMINES THE VASCULAR BUT NOT THE CARDIAC EFFECTS OF EXERCISE TRAINING THROUGH ENDOTHELIAL NOS ACTITIVY

de Bono, JP1; Adlam, D1; Zhang, MH1; Paterson, DP2; Channon, KM1


261

VENOSELECTIVITY OF NITRITE – EVIDENCE FAVOURING HYPOXIC RELEASE OF NO

Maher, AR1; Gunaruwan, P1; Abozguia, K1; Palin, T1; James, P2; Frenneaux, MP1

1. University of Birmingham, Birmingham, United Kingdom; 2. University of Wales, Cardiff, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

100

253

CAN WE RELY ON TISSUE VELOCITY PROFILES WHEN STUDYING LV DYSYNCHRONY?

Marciniak, M; Baltabaeva, A; Marciniak, A; Parsai, C; Bijnens, B; Sutherland, GR

St George’s Hospital, London, United Kingdom

254

HIGH SPATIAL-RESOLUTION MYOCARDIAL PERFUSION MR IMAGING USING K-T SENSE

Plein, S1; Ryf, S2; Boesiger, P2; Greenwood, J1; Radjenovic, A1; Kozerke, S2; Schwitter, J3

1. University of Leeds, Leeds, United Kingdom; 2. ETH and University of Zurich, Zurich, Switzerland; 3. University Hospital Zurich, Zurich, Switzerland

255

THE EFFECT OF GROWTH HORMONE UPON CARDIAC FUNCTION AND EXERCISECAPACITY IN PATIENTS WITH ADULT ONSET GROWTH HORMONE DEFICIENCY

Windram, JD1; Gonzalez, S2; Ingle, L1; Nikitin, N1; Clark, AL1; Atkin, SL2

1. Academic Cardiology, Hull Royal Infirmary, Hull, United Kingdom; 2. Department of Academic Endocrinology, Hull Royal Infirmary, Hull, United Kingdom


Vascular biology

Chair: Prof Martin Bennett and Prof Jeremy Pearson

256

GENETIC LINEAGE TRACKING OF HAEMATOPIETIC CELLS USING THE CRE LOXSYTSEM TO INVESTIGATE THE ROLE OF ENDOTHELIAL PROGENITOR CELLS INNORMAL VASCULAR DEVELOPMENT AND AFTER VASCULAR INJURY IN MICE

Wragg, A1; Mellad, J2; San, H2; Mathur, A1; Boehm, M2

1. The London Chest Hospital, London, United Kingdom; 2. National Institutes of Health, Bethesda, United States

103

266

SUCCESS AND CLINICAL OUTCOME OF CATHETER ABLATION FORSUPRAVENTRICULAR TACHYCARDIA IN PATIENTS WITH SEVERE PULMONARYHYPERTENSION WITHOUT CONGENITAL HEART DISEASE: A CASE SERIES REPORT

Showkathali, R1; Alzetani, M1; Grapsa, J1; Nihoyannopoulos, P2; Howard, L SGE2; Lefroy, D2; Gibbs, JSR2

1. Hammersmith Hospital, London, United Kingdom; 2. Hammersmith Hospital and Imperial College, London, United Kingdom

267

TYPE 2 DIABETICS ON CHRONIC LISINOPRIL THERAPY EXHIBIT GRADUALREACTIVATION OF VASCULAR TISSUE ANGIOTENSIN I TO ANGIOTENSIN IICONVERSION

Sharman, D; Morris, A; Struthers, A

Division of Medicine & Therapeutics, Ninewells Hospital, Dundee, United Kingdom

268

CHRONIC HEART FAILURE PATIENTS ON LISINOPRIL VERSUS RAMIPRIL THERAPYEXHIBIT NO DIFFERENCE IN THE REACTIVATION OF VASCULAR TISSUEANGIOTENSIN I TO ANGIOTENSIN II CONVERSION

Sharman, D; Struthers, A

Division of Medicine & Therapeutics, Ninewells Hospital, Dundee, United Kingdom

269

THE EFFECT OF BLOOD PRESSURE REDUCTION ON RENAL FUNCTION IN PATIENTSWITH ESSENTIAL HYPERTENSION

Lim, S; Patel, JV; Lip, GYH

City Hospital, Birmingham, United Kingdom

270

PATIENTS WITH HEART FAILURE AND CHRONIC OBSTRUCTIVE PULMONARYDISEASE MAY BE INAPPROPRIATELY DENIED BETA-BLOCKERS

Hawkins, NM1; Jenkins, SMM1; MacDonald, MR2; McMurray, JJ3; Dunn, FG1

1. Stobhill Hospital, Glasgow, United Kingdom; 2. Glasgow Royal Infirmary, Glasgow, United Kingdom; 3. Western Infirmary, Glasgow, United Kingdom

CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

102

262

OVEREXPRESSION OF HEPATOCYTE GROWTH FACTOR ACCELERATESMINERALISATION OF HUMAN SMOOTH MUSCLE CELLS IN VITRO

Liu, Y; Wilkinson, FL; Heagerty, AM; Canfield, AE; Alexander, MY


263

PAR-1 CAUSES ARTERIAL VASODILATATION VIA A TETRAETHYLAMMONIUM-SENSITIVE ENDOTHELIUM-DERIVED HYPERPOLARISING FACTOR IN MAN

Lang, NN1; Gudmundsdottir, IJ1; Boon, NA2; Newby, DE1

1. University of Edinburgh, Edinburgh, United Kingdom; 2. Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

264

ENDOTHELIAL FUNCTION, INFLAMMATION AND SERUM LIPID IN PATIENTS WITHCORONARY ARTERY DISEASE TREATED WITH STATINS

Agarwal, SC1; Allen, J1; Murray, A2; Purcell, IF1

1. Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2. Freeman Hospital, Newcastle Upon Tyne, United Kingdom


Hypertension, pulmonary hypertension and CV pharmacology

Chair: Prof Anna Dominiczak and Dr Jean McEwan

265

COMBINATION THERAPY FOR SCLERODERMA ASSOCIATED PULMONARY ARTERIAL HYPERTENSION

Kabunga, P1; Bloore, D1; Das, C1; Handler, CE1; Vrapi, F1; Denton, C2; Black, CM2; Smith, CJ3; Coghlan, JG1

1. Department of Cardiology Royal Free Hospital, London, United Kingdom; 2. Department of Rheumatology,Royal Free Hospital, London, United Kingdom; 3. Department of Primary Care and Population Sciences, Royal Free & University College Medical School, London, United Kingdom

105 CP

D a

nd r

esea

rch

day

Thur

sday

7 J

une


Programme

104

271

MEASURING RESPONSE TO CLOPIDOGREL IN PATIENTS UNDERGOING CORONARYINTERVENTION; A COMPARISON OF TWO METHODS

Good, RIS1; McGarrity, A1; Miller, H1; James, TE2; McConnachie, A3; Hillis, WS1; Goodall, AH2; Oldroyd, KG1

1. Western Infirmary, Glasgow, United Kingdom; 2. University of Leicester, Leicester, United Kingdom; 3. University of Glasgow, Glasgow, United Kingdom

272

EVALUATION OF THE INTRODUCTION OF ANTI-PLATELET CARDS FOR PATIENTSPOST PERCUTANEOUS CORONARY INTERVENTION

Pottle, A; Breen, J; Joseph, T; King, S

Harefield Hospital, Harefield, United Kingdom

273

LEFT ATRIAL REMODELLING AND REGIONAL DEFORMATION IN MILD TO MODERATEHYPERTENSION

Baltabaeva, A1; Marciniak, M2; Bijnens, B1; He, F2; Antonios, T2; MacGregor, G2; Sutherland, G1

1. St. George’s Hospital, London, United Kingdom; 2. St. George’s University London, London, United Kingdom

Lomond 12.30-13.30Debate: This house believes that it would choose a bare metal stent

for its own proximal LAD angioplasty

Chair: Dr Huon Gray and Dr Stephen Holmberg

For: Dr Rodney Stables

Against: Dr Martyn Thomas

Close 13.30

107

Barret J see Brown B et alBarth J see Cubbon R et al

see Das R et alsee Younger J et al

Basavarajaiah S et al. Prevalence and significance of an isolated long QTC interval on 12-lead ECG in elite athletes, p79

Prevalence of hypertrophic cardiomyopathy in eliteathletes, p54

Bashir Y see Tomlinson D et alBasmadjian A see Berry C et alBatin P see Gale C et alBaudoin F see Cartwright E et al

see Mohamed T et alBaumbach A see Balachandran K et al

see Smith D et alBeale L see Silberbauer J et alBeattie J see Pitt J et alBeen M see DeGiovanni J et alBehan M see Blows L et alBell A see Hamour I et alBennett R see Smith A et alBergmann A see Khan S et alBerry C et al. Corevalve percutaneous aortic valve

replacement: North American experience, p48Does a strategy of selective biomarker testing following

percutaneous coronary intervention miss prognosticallyimportant procedure-related myocardial infarctions?, p56

Betts T see Tomlinson D et alBeynon R see Fox D et alBhamra G see Hausenloy D et alBhan A et al. Assessment of myocardial perfusion:

can it be done using real-time 3D echo?, p85Bhattacharyya S et al. NT-proBNP as a biomarker

for the development of carcinoid heart disease, p86Prevalence of carcinoid heart disease in the modern era, p54Severity of carcinoid heart disease and relationship with

NTproBNP, p99 Bijnens B see Baltabaeva A et al

see Kiotsekoglou A et alsee Marciniak M et alsee Orlando S et alsee Parsai C et al

Bilodeau L see Berry C et alBingham A et al. Genetic dissection of a blood pressure

quantitative trait locus on rat chromosome 1 and geneexpression analysis identifies spon1 as a novel candidatehypertension gene, p25

Birkhead J see Gale C et alBishop J see Jhund P et alBlack C see Kabunga P et alBlackman D see Crean A et al

see Jani M et alBlaxill J see Crean A et al

see Jani M et alBlomberg A see Mills N et alBloore D see Kabunga P et alBlows L et al. Assessment of standards of percutanous

interventional practice: development of a network-widepeer review audit process, p80

Comparison between pressure derived and thermodilutionderived flow reserve in patients undergoingpercutaneous coronary intervention, p98

Boehm M see Wragg A et alBoesiger P see Plein S et alBonan R see Berry C et alBonhoeffer P see Coats L et al

Bonner Z see Velupandian U et alBoodhoo L et al. Why do some patients with

Wolff–Parkinson–White syndrome present later in life?, p72Boon N see Lang N et al

see Mills N et alBooth J see Stables R et alBordoli G see Arya A et alBoreham P see Sandilands A et alBorer J see Savelieva I et alBorg A see Fox D et alBorg A et al. Abnormal left ventricular torsion in chronic

mitral regurgitation: a speckle tracking echocardiographystudy, p84

Bourantas C see Papafaklis M et alBourantas C et al. The prevalence and prognostic value

of atherosclerotic renal artery stenosis in patients withleft ventricular systolic dysfunction, p98

Bourke J see Raine D et alBowater S et al. Management of repaired and native

maternal aortic coarctation during pregnancy, p55Bowden J see Greaves K et alBradding P see Maznyczka A et alBrady A et al. Cost effectiveness of ezetimibe co-

administration vs doubling statin dose in patients not atcholesterol targets on statin monotherapy in the UK, p61

Brady P see Lin G and Brady P Bragadeesh T et al. Myofibrillar oedema causes

post-ischaemic myocardial dysfunction, p75 Braund P see Maznyczka A et alBraunwald E see Ray K et alBrecker S see Sharma R et alBreen J see Pottle A et alBrett S see Munir S et alBrickley G see Silberbauer J et alBroadhurst D see Deepak S et alBrook G see Loo B et alBrooks N see Deepak S et al

see Gupta S et alBrouilette S see Whittaker A et alBrown B et al. Interleukin 1 is significantly associated with

CAD in a large UK discordant sibship collection, p25Bryan A see Narayan P et alBuch M see Deepak S et alBuchan K see Gibson P et alBuening H see White K et alBurden L see Hickman M et al

see Jeetley P et alBurke M see Hamour I et alBurton P see Hajat C et alBuscombe J see Vrapi F et alButler R, Wainwright J An audit of high dose vs

standard dose lipid-lowering therapy following acute myocardial infarction: the patient costs resulting from a financially-motivated drug change in North Staffordshire, p80

Butler R see Freestone B et alsee Lo T et alsee Tan Y et al

Cairns K see Hamilton A et alsee Moore M et al

Calderwood R see Velupandian U et alCamici P see Cook S et al

see Lu H et alCamm A see Bajpai A et al

see Kiotsekoglou A et alsee Savelieva I et al


Author index

106

Abozguia K see Maher A et alAbrams D see Kistler P et al

see Rajappan K et alAdgey A see Hamilton A et al

see Moore M et alAdlam D see de Bono J et alAdlam D et al. Differential role of nNOS in heart rate

regulation between rest and exercise, p42 Agarwal S et al. Endothelial function, inflammation and

serum lipid in patients with coronary artery diseasetreated with statins, p102

Ahmad I see Dhawan A et alAhmed A see Lambiase P et al

see Rogers D et alAhmed A et al. Does conduction delay in the right

ventricular outflow tract underlie arrhythmogenesis in Brugada syndrome? A non-contact endocardial mapping study, p72

Aitman T see Lu H et alsee Sarwar R et al

Alahmar A see Andron M et alAlahmar A et al. No difference in 2-year mortality between

drug-eluting stent and bare-metal stent implantation in ‘‘real world’’, p68

Serum creatinine concentration is an independent predictorof long-term mortality following percutaneous coronaryintervention; drug-eluting stent implantation reduces this risk, p69

Alatwi N see Mohamed T et alAlbouaini K see Alahmar A et alAlemao E see Brady A et alAlexander M see Liu Y et alAlfakih K et al. Introduction of integrated nurse specialist

led management of acute coronary syndrome patients: an audit, p81

Ali M et al. Uncomplicated obesity is characterised by alteredsystolic and diastolic myocardial velocities as assessed byphase contrast magnetic resonance imaging, p99

Allen J see Agarwal S et alsee Masson R et al

Alp N see Reilly S et alAlton L see Koa-Wing M et alAlzetani M see Showkathali R et alAnand D see Lim E et alAnand D et al. Determinants of progression of coronary

artery calcification in type 2 diabetes, p74 Anand R see Greaves K et alAnderson L see Parsai C et alAnderson R see Willis J et alAndrews C see Balakrishnan G et alAndron M see Alahmar A et alAndron M et al. Impact of periprocedural creatine

kinase-MB isoenzyme elevation on long-term mortalityafter percutaneous coronary intervention, p83

Ang R see Smith E et alAngelini G see Narayan P et al

see Smith D et alAnker S see Okonko D et alAntoniades C see Shirodaria C et alAntonios T see Baltabaeva A et alAntony R see Alahmar A et alAntony R et al. Comparison of clinical outcomes in small

vessel percutaneous coronary intervention before andafter the introduction of drug-eluting stents, p68

Archbold R see Sulfi S et alArchbold S see Strange J et alArnold J see Pegg T et al

Arnold J et al. Do patients undergoing percutaneouscoronary intervention still require consenting foremergency coronary bypass surgery?, p83

Artis N et al. 2D-Strain derived anteroseptum to posteriorwall delay predicts reverse remodelling after cardiacresynchronisation therapy, p70

Arya A see Veasey R et alArya A et al. ‘‘MINVPACE’’: a study comparing minimal

ventricular pacing and preventive atrial fibrillationalgorithms in the treatment of PAF, p94

All-cause and cardiovascular mortality related to long-termrate or rhythm control strategies in patients undergoingsedation dc cardioversion for atrial fibrillation, p94

Asgar A see Berry C et alAshley E see Mwamure P et alAston K see Koa-Wing M et alAthanasopoulos G see Kiotsekoglou A et alAtkin S see Windram J et alAvery G see Wright G et alAvery P see Haddadin F et al

see Imrie H et alsee Rahman T et al

Avlonitis V et al. Video-assisted thoracoscopic ablation for treatment of atrial fibrillation, p73

Aziz S see Antony R et al

Badimon J see Natarajan A et alBajpai A see Kiotsekoglou A et alBajpai A et al. Assessment of ventricular function

in atrial fibrillation: single beats with equal preceding and pre-preceding R-R intervals allow accurateestimation of left ventricular systolic function, p71

Baker A see Masson R et alsee White K et al

Baker M see Rahman T et alBakhai A see Balakrishnan G et al

see Vrapi F et alBalachandran K et al. Drug-eluting stents are not

associated with an increase in all-cause mortality: resultsfrom a single tertiary centre following NICE guidelines, p80

Balakrishnan G et al. Feasibility of diagnosing andquantifying metabolic syndrome in consecutive acutemedical admissions, p56

Balami D see Sulfi S et alBaliga V see Gale C et alBall S see Plein S et al

see Younger J et alBalmain S see MacDonald M et alBalmforth A see Brown B et alBaltabaeva A see Marciniak M et al

see Orlando S et alsee Parsai C et al

Baltabaeva A et al. Left atrial remodelling and regionaldeformation in mild to moderate hypertension, p104

Banasiak W see Okonko D et alBanerjee R see Hamour I et alBankart J see Descamps M et alBanner N see Hamour I et alBanning A see Arnold J et al

see Cheng A et alsee Jin X et alsee Ryding A et alsee Selvanayagam J et al

Bansi D see Tenkorang J et alBarker D see Lewis N et alBarnard M see Mwamure P et alBarrass K see Collerton J et al

109

Cubbon R et al. Hyperglycaemia, in relation to gender, and mortality after acute coronary syndrome, p95

Temporal trends in mortality of patients with diabetes mellitussuffering acute myocardial infarction: a comparison of over3000 patients between 1995 and 2003, p96

The role of secondary prevention strategies in patients with diabetes mellitus sustaining an acute coronarysyndrome: time for a critical reappraisal?, p60

Culliford L see Smith D et alCunningham A see McComb J et al

see Plummer C et alCunningham M see McComb J et al

see Plummer C et alCunnington M et al. Delays to permanent pacemaker

implantation: an explanation for low implantation rates in the United Kingdom?, p94

Currie P see O’Neill L et alCurtis S see Manisty C et alCurzen N see Hobson A et al

see Hobson A et alCuthbertson B see Gibson P et alCzygan G see Mudawi T et al

Dalby M et al. Delays in delivering primary angioplasty withinterhospital transfer result in limited mortality benefit inreal-world practice in the context of a high-qualitythrombolysis service, p22

Dargie H see Watkins S et alDarko D see Anand D et alDarrel D see Davies J et alDas C see Kabunga P et alDas R et al. A simple risk model for predicting 30-day

mortality in patients presenting with acute coronarysyndrome, p95

Davar J see Bhattacharyya S et alDavenport A see Vrapi F et alDavidson N see Fox D et alDavidson S see Hausenloy D et al

see Shiang-Yong L et alsee Simpkin J et al

Davies D see Koa-Wing M et alDavies E see Imrie H et alDavies G see Brady A et al

see Wright G et alDavies J see Hadjiloizou N et al

see Khan S et alsee Manisty C et alsee Sugden J et al

Davies J et al. A unifying explanation of the arterial pulsewaveform in humans and the implications for centralblood pressure augmentation, p87

Dawkins K see Hobson A et alDe Backer G see Connolly S et alde Belder A see Blows L et alde Belder M see Kunadian B et al

see Thornley A et alsee Tough J et alsee Turley A et al

de Bono J see Adlam D et alde Bono J et al. Discordant response to exercise training

in nNOS knockout mice: differential role of nNOS onexercise performance versus cardiac hypertrophy, p47

Presence of atherosclerosis determines the vascular but not the cardiac effects of exercise training throughendothelial NOS activity, p101

De Giovanni J see Mullen M et alde Silva R see Bourantas C et al

Deane J see Thakaran G et alDeanfield J see Coats L et alDeBacquer D see Connolly S et alDeepak S et al. Serum metabolomic analysis successfully

discriminates heart failure patients from controls, p87 DeGiovanni J et al. Transcatheter closure of paravalvar

prosthetic valve leaks using the amplatzer occluders, p97Denault A see Berry C et alDenton C see Kabunga P et alDerrick G see Coats L et alDescamps M et al. Plasma brain natriuretic peptide predicts

outcome in patients with fractured neck of femur, p86 Dewhurst N see O’Neill L et alDhawan A et al. Cardiac arrhythmias in women with

palpitations of pregnancy associated with symptoms, p50Minor troponin T rise in new onset atrial fibrillation

significantly increases future cardiovascular risk, p61 Dhillon O see Khan S et alDhinoja M see Ahmed A et al

see Rogers D et alDi Salvo C see Mwamure P et alDixon G see Blows L et alDixon R see Bingham A et alDo P see Yan Y et alDonaldson K see Mills N et alDonnan P see Shah N et alDorman S see Johnson T et alDorsch M see Crean A et alDougal C see Bajpai A et alDowson A A prospective, multicentre, randomised, double

blind, placebo-controlled trial to evaluate the efficacy ofpatent foramen ovale closure with the STARFlex septalrepair implant to prevent refractory migraine headaches:the MIST Trial, p48

Dreyfus G see Hamour I et alDu X, Jin X The time course of improvement in ECG strain

pattern after AVR for aortic stenosis and its underlyingmechanisms, p58

Ducharme A see Berry C et alDudley F see Gale C et alDuke C see Mullen M et alDuncan E see Ezzat V et alDunn F see Hawkins N et al

see Nisbet A and Dunn F Dunn W see Deepak S et alDunning J see Kunadian B et alDupuis J see Berry C et alDutka D see Khan S et alDwivedi G et al. Extent of myocardial viability detected

by myocardial contrast echocardiography early after acute myocardial infarction is an independent predictor of mortality and re-infarction, p70

The extent of residual contrast perfusion and not leftventricular function predicts late recovery of globalcontractile function after acute myocardial infarction and reperfusion therapy, p84

Dwivedi G see Hayat S et alsee Lim T et al

Earley M see Rajappan K et alEden J see Palomino Doza J et alEdgar D see Mudawi T et alEdmond J see Balachandran K et alEdwards C see Arya A et alEdwards N et al. Safety of spironolactone with ACE

inhibitors/angiotensin receptor blockade in patients with chronic kidney disease, p67


Author index

108

Campbell R see Mahadevan G et alCanfield A see Liu Y et alCannon C see Ray K et alCapewell S see Jhund P et alCaplin M see Bhattacharyya S et alCaputo M see Narayan P et alCarby L see Basavarajaiah S et alCarlsson J see MacDonald M et alCarr R see Hausenloy D et alCarrick A see Good R et alCarroll D see Thrall G et alCartwright E see Mohamed T et alCartwright E et al. Cardiac and systems biology of isoform

4 of the plasma membrane calcium ATPase, p42Carver A see Gershlick A et al

see Swanson N et alCasadei B see Adlam D et al

see de Bono J et alsee Reilly S et al

Cassidy J see Kirk C et alCave M see Thornley A et alChalil S et al. Effect of posterolateral left ventricular

scar on mortality and morbidity following cardiacresynchronisation therapy: a late gadoliniumenhancement cardiovascular magnetic resonance study, p93

Intraventricular dyssynchrony predicts mortality andmorbidity following cardiac resynchronisation therapy: a study using cardiovascular magnetic resonance tissuesynchronisation imaging, p93

Long-term effects of cardiac resynchronisation therapy in patients with chronic atrial fibrillation, p91

Chalmers J see Jhund P et alChamberlain J see Masson R et alChanner K see Smith A et al

see Whittaker A et alsee Adlam D et alsee Arnold J et alsee de Bono J et alsee de Bono J et alsee Selvanayagam J et alsee Shirodaria C et al

Chantler PD see Lewis NT et alCharchar F see Bingham A et alCharles R see McComb J et al

see Plummer C et alChaudhari M see Raine D et alCheek E see Silberbauer J et al

see Veasey R et alChen Z see Smith E et alCheng A et al. Cardiovascular magnetic resonance

perfusion imaging at 3 tesla for the detection of coronaryartery disease: a comparison with 1.5 tesla, p45

Cheng A see Selvanayagam J et alCheng Z see Strange J et alChild A see Kiotsekoglou A et alChild N see Milborrow G et alChiwara M see Gibson P et alChlebinska A see Basavarajaiah S et alChong N see Mahadeva H et al

see Ounzain S et alChoudhury R see Cheng A et alChow A see Ahmed A et al

see Lambiase P et alsee Rogers D et al

Chowienczyk P see Munir S et alsee Seddon M et al

Clark A see Bourantas C et alsee Khan N et alsee Loh P et alsee Windram J et al

Clarke K see Hudsmith L et alClayton N see Fox D et al

see Gupta S et alClayton T see Stables R et alCleland J see Bourantas C et al

see Khan N et alsee Loh P et al

Clements RE see Lewis NT et alClemitson J see Bingham A et alClift P see Bowater S et alClose J see Thornley A et alCoats L et al. Physiological adaptation to acute relief

of adverse right ventricular loading conditions, p49Cockburn K see Wright G et alCockerill G see Kelly D et alCoghlan J see Kabunga P et al

see Vrapi F et alColes D see Smith D et alCollerton J et al. White blood cell telomere length is

associated with left ventricular function in the oldest old:the Newcastle 85+ study, p47

Collier T see Connolly S et alsee Martins J et al

Collinson P see Sharma R et alCollitt S et al. Influence of genetic testing on implantation

of implantable cardioverter defibrillators in patients withsuspected ion channelopathies, p78

Connell J see Imrie H et alsee Rahman T et al

Connolly D see Toner P et alConnolly M see Toner P et alConnolly S et al. Euroaction: a European Society

of Cardiology demonstration project in preventivecardiology: one-year results for coronary patients and their partners, p39

Cook J see Brady A et alCook S see Lu H et al

see Sarwar R et alCook S et al. Common abnormalities of insulin action

in patients with diabetes and heart failure, p59 Coppinger T see Gupta S et alCordell H see Imrie H et alCorder R see Anand D et alCowen M see Smith A et alCowie M see Roughton M et al

see Lau-Walker M and Cowie M Cox H The cardiac educational needs and competencies

of emergency care nurses, p50 Craig J see Haq I et alCrawfurd E see Descamps M et alCrean A see Younger J et alCrean A et al. Outcome of primary percutaneous coronary

intervention in the very elderly, p81Cripps T see Sandilands A et al

see Sandilands A and Cripps T Critoph C see Strange J et alCroal B see Gibson P et alCrossman D see Lawrie A et alCrozier I see Graham L et alCruden N see Japp A et alCruden N et al. Reduced vascular complications and

length of stay with transradial rescue angioplasty foracute myocardial infarction, p82

111

Grainger R see Antony R et alGranger C see MacDonald M et alGrant P see Cubbon R et alGrapsa J see Showkathali R et alGray D see Moore M et alGrayson A see Alahmar A et al

see Alahmar A et alGrayson T see Andron M et alGreaves K see Dwivedi G et al

see Wennicke N et alGreaves K et al. Contrast ultrasonography: a novel

application for the assessment of graft perfusion, p70 Green R see Kesavan S et alGreenwood D see Gale C et alGreenwood J see Crean A et al

see Jani M et alsee Plein S et alsee Younger J et al

Gregan S see Finch J et alGregorevic P see Masson R et alGregson H see Sharma R et alGreszlo A see Okonko D et alGriffin H et al. Mutations in the cardiac transcription

factor TBX1 may contribute to susceptibility to tetralogy of Fallot in patients without 22Q11 deletion, p25

Grocott-Mason R see Dalby M et alGrundy E see Mwamure P et alGudmundsdottir I see Lang N et alGuilcher A see Munir S et alGunarathne A see Lim H et alGunaruwan P see Maher A et alGunn J see Siotia A et alGunning M see Freestone B et al

see Lo T et alee Tan Y et al

Gupta D see Kistler P et alsee Rajappan K et al

Gupta S et al. The effect of introducing diuretics incompensated patients with left ventricular dysfunction on quality of life, plasma BNP levels, NBNP levels and peak oxygen consumption: results from a doubleblind, placebo controlled crossover study, p44

Haddadin F et al. Very high prevalence of sleep apnoeasymptoms in patients who have undergone electiveelectrical cardioversion for atrial fibrillation, p53

Hadjiloizou N see Davies J et alsee Manisty C et al

Hadjiloizou N et al. The effect of regional wall motionabnormalities on coronary haemodynamics, p83

Hague A see Keeble T et alHague C see Crean A et alHaines S see Bingham A et alHajat C et al. Heritability of the QTC interval: analysis

in a population-based family study, p85Hale A see Reilly S et alHall A see Brown B et al

see Cubbon R et alsee Das R et alsee Gale C et al

Hall D see Rahman T et alHall J see Kunadian B et alHall L see Bingham A et alHall M see Boodhoo L et al

see Kirubakaran S et alHall1 J see Thornley A et alHallek M see White K et alHalliday A see Wheeler S et al

Hamilton A see Moore M et alHamilton A et al. Risk factors in patients with an

out-of-hospital cardiac arrest, p96Hamilton L see Raine D et alHamilton M see Smith D et alHamour I et al. Heart transplantation in the current era:

a 10-year perspective, p60The changing risk:benefit ratio of endomyocardial

biopsies with improved immunosuppression after heart transplantation, p60

Handler C see Kabunga P et alHaq I et al. Implications of guidelines for statin treatment

for secondary prevention of cardiovascular disease: riskfactor analysis of the Scottish Health Survey 2003, p38

Harcombe A see Alfakih K et alHarris J see Mwamure P et alHarris S see Kistler P et al

see Rajappan K et alHarrison J see Borg A et alHasan A see Kirk C et al

see Raine D et alHaskard D see Finch J et alHausenloy D see Mudalagiri N et al

see Mwamure P et alsee Shiang-Yong L et al

Hausenloy D et al. Glimepiride treatment facilitates theprotective effect of ischaemic preconditioning in thediabetic heart, p42

Metformin given at time of reperfusion reduces myocardialinfarct size through the Akt-mediated inhibition ofmitochondrial permeability transition pore opening, p41

The adipocytokine, visfatin, reduces myocardial infarctsize, when given at time of reperfusion, by inhibiting themitochondrial permeability transition pore, p41

Hawkins N see MacDonald M et alHawkins N et al. Patients with heart failure and chronic

obstructive pulmonary disease may be inappropriatelydenied beta-blockers, p103

Hayat S see Dwivedi G et alsee Lim T et al

Hayat S et al. Partial volume effect, not hypoperfusion, isthe cause of perfusion defects on single photon emissioncomputed tomography in left bundle branch blockpatients without coronary artery disease: a quantitativemyocardial contrast echocardiography study, p71

Hayward M see Mwamure P et alHe F see Baltabaeva A et alHeagerty A see Liu Y et al

see Velupandian U et alHeck P see Khan S et alHemingway H see Zaman M et alHenderson D, Phillips H Planar cell polarity signalling

plays crucial roles in outflow tract development, p57Henderson R see O’Brien D et alHerring E see Velupandian U et alHetherington S see Lo T et al

see Whittaker A et alHickman M see Greaves K et alHickman M et al. Resting myocardial blood flow

not myocardial flow reserve predicts hibernatingmyocardium: a quantitative myocardial contrastechocardiography study, p69

Hildick-Smith D see DeGiovanni J et alsee Lo T et alsee Mullen M et al

Hill J see Haq I et alHillis G see Gibson P et al


Author index

110

Egred M see Alahmar A et alsee Andron M et al

Ehtisham J see Tomlinson D et alEl Gaylani N see Pitt J et alEl-Shafei H see Gibson P et alElder D see O’Neill L et alElkeles R see Flather M et alEllery S see Williams L et alElliott P see Lambiase P et alEllis D see Deepak S et alEllis S see Kistler P et alEmmanuel Y see Hudsmith L et alEngland F see Rogers D et alEpstein F see Bragadeesh T et alEteiba H see Pell J et alEttles D see Bourantas C et alEzzat V et al. IGFBP-1 protects against obesity-induced

vascular dysfunction by preservation of insulin signalling, p101

Fairbrother K see Gershlick A et alFarrall M see Imrie H et al

see Rahman T et alFeder G see Zaman M et alFeher M see Flather M et alFelix P et al. Arrhythmia burden in adults with congenital

heart disease in a level 2 GUCH centre, p58 Ferguson P see Moore M et alFerro C see Edwards N et alFinch D see Balachandran K et alFinch J et al. NF-κB inhibition by blockade of IKK-2 and

MYD88 in vein graft smooth muscle cells reduces theexpression of key mediators of intimal hyperplasia, p47

Findlay I see Ray G et alFirman E see Lambiase P et alFischer J see Sarwar R et alFitzpatrick A see Fox D et alFitzsimons E see Murphy C et alFlapan A see Japp A et al

see Pell J et alFlather M see Stables R et alFlather M et al. Predictors of progression of coronary artery

calcium in type 2 diabetes: the PREDICT Study, p74Foale R see Davies J et al

see Hadjiloizou N et alFoldes G see Okonko D et alFollath F see Khan N et alFord I see Watkins S et alForfar J see Arnold J et alFoster J see Watkins S et alFotiadis D see Papafaklis M et alFountzopoulos E see Freestone B et al

see Lo T et alFox D see Borg A et alFox D et al. Echocardiographic optimisation of

inter-ventricular delay improves exercise performancecompared to simultaneous biventricular pacing, p93

Fox J see Innasimuthu A et alFox K see Martins J et al

see Roughton M et alsee Tenkorang J et al

Foxwell B see Finch J et alFrancis D see Hadjiloizou N et al

see Manisty C et alFrancis J see Ali M et al

see Hudsmith L et alsee Shirodaria C et al

Francis S see Lawrie A et alFraser R see Imrie H et alFreel M see Imrie H et alFreeman L see Felix P et alFreemantle N see Khan N et alFreestone B see Lo T et alFreestone B et al. Contemporary ST elevation myocardial

infarction management: results of a hybrid lyticprogramme are equivalent to primary percutaneouscoronary intervention, p55

Frenneaux M see Mahadevan G et alsee Maher A et alsee Williams L et al

Gaffney T see Ray G et alGale C see Cubbon R et al

see Das R et alGale C et al. Profiling English hospital mortality rates for

acute coronary syndromes using the MyocardialInfarction National Audit Project database, p68

Using case-mix adjusted funnel plots of 30-day mortalityfor acute coronary syndromes to explore hospitalperformance, p56

Using the Myocardial Infarction National Audit Projectdatabase to validate acute coronary syndrome riskscores by subgroup risk, p56

Gale R see Gale C et alGanaraj L see Dhawan A et alGandhi N see Gupta S et alGardiner H see Matsui H et alGarratt C see Collitt S et al

see Kirubakaran S et alGarratt C What risk of death would you accept before

having an implantable cardiac defibrillator?, p78 Gaze D see Sharma R et alGedney J see Turley A et alGeorge K see Lewis NT et alGershlick A see Swanson N et alGershlick A et al. The REACT (rescue angioplasty vs

conservative treatment or repeat thrombolysis) trial: longer-term follow-up, p22

Ghani F see Lim E et alGhimire G see Dalby M et alGibbs J see Showkathali R et alGibson G see Gibson P et alGibson P et al. Preoperative neutrophil-lymphocyte ratio

and outcome from coronary artery bypass grafting, p98Renal function and outcome from valve surgery, p57 Gidden D see Descamps M et alGilthorpe M see Gale C et alGlover B see Moore M et alGodsland I see Flather M et alGoldspink DF see Lewis NT et alGonzalez M see Mills N et alGonzalez S see Windram J et alGood R et al. Differences between the European and

American society guidelines influence the number andduration of chest pain admissions, p38

Measuring response to clopidogrel in patients undergoingcoronary intervention: a comparison of two methods, p104

Goodall A see Good R et alsee Maznyczka A et al

Goode K see Khan N et alsee Loh P et al

Goodship J see Griffin H et alGracey J see Hajat C et alGraham L et al. CT guided transseptal left heart

catheterisation for left atrial ablation: a novel technique, p72

113

Katz J see Balakrishnan G et alKaul S see Bragadeesh T et alKaye G see Mudawi T et alKearney M see Cubbon R et al

see Ezzat V et alKeavney B see Collerton J et al

see Griffin H et alsee Imrie H et alsee Palomino Doza J et alsee Rahman T et al

Kedhi E see Berry C et alKee F see Hamilton A et al

see Moore M et alKeeble T et al. Two-year follow-up of 410 patients

presenting to a district general hospital with chest painand a CT coronary calcium score of zero, p46

Keenan N, Pennell D Age-related changes in carotidartery lumen and wall volume in a population free ofcardiac risk factors, p96

Kell D see Deepak S et alKelly D see Swanson N et alKelly D et al. Plasma MMP-9 and TIMP-1: novel markers

of left ventricular dysfunction and adverse prognosisafter acute myocardial infarction in man, p43

Kelly P see Keeble T et alKenny M see Collerton J et alKeogh B see Mwamure P et alKerzin-Starr L see Collitt S et alKesavan S et al. The effect of obstructive sleep apnoea

on left atrial and left ventricular structure, p54Khadjooi K see Chalil S et alKhaghani A see Hamour I et alKhaleva O see Loh P et alKhambadone S see Coats L et alKhan A et al. The impact of percutaneous atrial septal

defect closure in the older population, p57 Khan N et al. Multimodel diagnostic tests to assess heart

failure using ECG, chest x ray and echocardiogram in patients with suspected heart failure, p53

Khan S et al. C-terminal pro-endothelin-1 offers additionalprognostic information with NTproBNP in patientsfollowing acute myocardial infarction. The LeicesterAcute Myocardial Infarction Peptide study, p43

C-terminal provasopressin (COPEPTIN) predicts risk ofdeath or heart failure in acute myocardial infarction. TheLeicester Acute Myocardial Infarction Peptide study, p89

Revascularisation for ischaemic myocardial dysfunctionleading to an improvement in ejection fraction is notassociated with an increase in long axis tissue Dopplervelocity, p75

Khan S see Dhawan A et alsee Kelly D et al

Khan T see Cook S et alsee Tan Y et al

Khan W see Borg A et alsee Fox D et al

Kharbanda R see Dalby M et alKhattar R see Fox D et alKhiani R see Velupandian U et alKhogali S see DeGiovanni J et alKhokhar A see Keeble T et al

see Sevant D and Khokhar A Kia R see Antony R et alKilcullen N see Das R et alKing S see Pottle A et alKiotsekoglou A see Bajpai A et al

Kiotsekoglou A et al. Impaired left ventricular long axisfunction in Marfan syndrome demonstrated by abnormalmitral annular displacement, p83

Kirk C et al. Infant assessment for cardiac transplantation, p57

Kirkwood T see Collerton J et alKirubakaran S et al. Physiological evidence of the

‘‘second factor’’ in atrial remodelling is accompanied by localised conduction abnormalities in the chronic goat model of atrial fibrillation, p71

Relative contribution of electrical and non-electrical(structural) remodelling on the atrial fibrillation circuit sizein the chronic goat model of atrial fibrillation, p71

Kistler P see Rajappan K et alKistler P et al. Electrophysiological and anatomic

characterisation of sites resistant to electrical isolationduring circumferential pulmonary vein ablation for atrialfibrillation: a prospective study, p91

The impact of image integration on catheter ablation of atrial fibrillation using electroanatomic mapping: a prospective randomised study, p41

Knight C see Smith E et alKnox E see Bowater S et alKoa-Wing M et al. Initial experience of catheter

ablation using a novel remotely steerable catheter sheath system, p73

Kojodjojo P see Koa-Wing M et alKolvekar S see Mwamure P et alKomajda M see Khan N et alKooner J see Lim E et alKotseva K see Connolly S et alKozerke S see Plein S et alKramer C see Bragadeesh T et alKumaran M see Sarwar R et alKunadian B see Thornley A et al

see Tough J et alsee Turley A et al

Kunadian B et al. Rescue angioplasty after failedfibrinolysis for acute myocardial infarction: predictors of a failed procedure and 1-year mortality, p82

Should patients in cardiogenic shock undergo rescueangioplasty after failed fibrinolysis? comparison of primaryvs rescue angioplasty in cardiogenic shock patients, p82

L’Allier PL see Berry C et alLaborde J see Berry C et alLahiri A see Anand D et al

see Lim E et alLamarche Y see Berry C et alLambert J see Berry C et alLambiase P see Ahmed A et al

see Rogers D et alLambiase P et al. Sudden arrhythmic death syndrome:

diagnostic yield of clinical screening in family members at the Heart Hospital, University College London, 2003–6, p91

Lane D see Thrall G et alLang N et al. PAR-1 causes arterial vasodilatation via a

tetraethylammonium-sensitive endothelium-derivedhyperpolarising factor in man, Ap102

Large J see Arya A et alLau-Walker M, Cowie M Coronary heart disease patients’

perception of their symptoms and sense of controlbefore hospital discharge predicts their quality of life inthe long term, p49

Laverty L see Toner P et al

Jeetley P et al. Stress echocardiography can safely,rapidly and accurately risk stratify patients withsuspected acute coronary syndrome and an initial (12 h)negative troponin: implications for early use of stressechocardiography in the emergency department, p26

Jeffrey R see Gibson P et alJeilan M see Descamps M et alJenkins S see Hawkins N et alJennings C see Connolly S et alJennings K see Pell J et alJerosch-Herold M see Cheng A et alJessani S et al. Impaired glucose tolerance is associated

with endothelial damage following acute myocardialinfarction, p61

Jhund P et al. Improving prognosis in heart failure: trendsin incident hospitalisation for heart failure andsubsequent survival between 1986 and 2003, p53

Sex difference in the relation between socioeconomicdeprivation and fatal versus non-fatal myocardial infarction, p56

Jiang B see Munir S et alsee Seddon M et al

Jin X see Du X and Jin X Jin X et al. Medium-term echocardiographic assessment of

heart failure patients implanted with an axial flow LVAD, p59The critical role of ERBB2 in human left ventricular

remodelling due to pressure or volume overload, p43 Johal VS see Yan Y et alJohnson M see Turley A et alJohnson T et al. Risk stratification in real-world acute

coronary syndromes: do conventional methods predictextent of coronary artery disease and need forrevascularisation?, p55

Jones J see Connolly S et alJones R see Smith A et alJones T see Smith A et alJordan P see Chalil S et alJoseph N see Balakrishnan G et alJoseph T see Pottle A et alJudge P see Yan Y et alJung B see Ali M et alJunghans C see Zaman M et alJux C see Mullen M et al

Kaba R see Koa-Wing M et alKabunga P see Vrapi F et alKabunga P et al. Combination therapy for scleroderma

associated pulmonary arterial hypertension, p102 Kakani N see van Lingen R et alKalla M see Rajappan K et alKalla M et al. A study to identify the prevalence and timing

of pericardial effusions after left atrial catheter ablationfor atrial fibrillation and atrial tachycardia, p40

Kalra S see Kalla M et alsee Rajappan K et al

Kanaganayagam G see Perera D et alKanagaratnam P see Koa-Wing M et alKapetanakis S see Bhan A et alKapur A see Sulfi S et alKaramitsos T see Arnold J et al

see Cheng A et alsee Pegg T et al

Karastergiou K see Kiotsekoglou A et alKaru T see Orlando S et alKaski J see Lambiase P et alKatsouras C see Papafaklis M et al


Author index

112

Hillis S see Mullen M et alsee Pell J et al

Hillis W see Good R et alHo E see Bhan A et alHo S see Matsui H et alHobbs F see Mahadevan G et alHobson A et al. Individual responses to aspirin using

a novel method of thrombelastogram analysis:hyporesponsiveness or poor compliance?, p69

Marked heterogeneity of individual responses to loadingdose clopidogrel employing a novel point of care test, p69

Holden A see Connolly S et alHood S see Ray G et alHoole S see Khan S et alHopkins D see Anand D et alHornick P see Finch J et alHoughton T see Mudawi T et alHoward L see Showkathali R et alHoward S see Felix P et alHu J see Jin X et alHuat C see Cruden N et alHubner N see Sarwar R et alHudsmith L et al. 31P cardiac magnetic resonance

spectroscopy during physiological leg exercise at 3 Tesla, p45

Hudsmith L see Bowater S et alHughes A see Davies J et al

see Hadjiloizou N et alsee Manisty C et al

Hughes E see Lim H et alHughes S see Lambiase P et alHunter S see Avlonitis V et alHussain R see Palomino Doza J et alHutchison E see Dalby M et al

Ibrahim R see Berry C et alIdigo W see Reilly S et alIfezulike A see Gibson P et alIlankovan V see Greaves K et alIlsley C see Dalby M et alImrie H et al. Association between aldosterone production

and variation in the gene encoding 11-beta hydroxylase(CYP11B1), p88

Ingle L see Windram J et alIngram M see Imrie H et alInnasimuthu A et al. Left dominant coronary arterial system

in aortic stenosis: an association, cause or effect, p58 Irving J see Pell J et al

Jackson C see Ali M et alsee Shirodaria C et al

Jackson M see Alahmar A et alsee Alahmar A et al

Jacobsen A see Hayat S et alJain P see Lim E et alJaisval S see Manisty C et alJames P see Maher A et alJames T see Good R et alJanardhanan R see Dwivedi G et alJani M et al. A one year experience of primary

percutaneous coronary intervention in Leeds: an audit of patients excluded from interventional therapy, p80

Japp A et al. The novel peptide, apelin, is a vasodilator in vivo in man, p46

Jardine A see Murphy C et alJayaweera R see Bragadeesh T et al

115

Marciniak M et al. Can we rely on tissue velocity profileswhen studying left ventricular dysynchrony?, p100

Marsh A see Mahadevan G et alMarshall A see Moore M et alMarshall S see Natarajan A et alMartin-Ruiz C see Collerton J et alMartins J et al. Incident atrial fibrillation and new heart

failure: the chicken or the egg? Insights from the ImperialCollege New AF Study, p53

The role of moderate alcohol intake in first detected atrialfibrillation: the Imperial College New AF Study, p54

Mason A see Mahadeva H et alMason M see Dalby M et alMasson R et al. Efficient cardiac gene delivery to

rat heart by intravascular injection of adeno-associatedvirus-6, p41

Mathers J see Balakrishnan G et alMathur A see Wragg A et alMathur G see Loh P et alMatsui H et al. Prediction of fetal coarctation of the aorta

from the three vessel and tracheal view, p57 Mavroudis C see Tan Y et alMayet J see Davies J et al

see Hadjiloizou N et alsee Manisty C et alsee Manisty C et al

Mayosi B see Imrie H et alsee Rahman T et al

Mazhar S see Keeble T et alMaznyczka A et al. Leukotriene B4 production in

subjects with variants of the 5-lipoxygenase activatingprotein gene associated with risk of myocardial infarction, p86

McCluskey D see Toner P et alMcCollum C see Velupandian U et alMcComb J, Plummer C Lack of knowledge of pacemaker

indications at the front line, p66Recognition of ECG abnormalities associated with

atrioventricular conduction defects, p91 McComb J see Cunnington M et al

see Plummer C et alMcComb J et al. Inequity of access to cardiac pacing:

results of a national survey, p67 McConnachie A see Good R et alMcDiarmid A see Cunnington M et alMcDowell G see Deepak S et alMcGarrity A see Good R et alMcGrath P see Toner P et alMcKenna W see Lambiase P et alMcLenachan J see Crean A et alMcLenchan J see Jani M et alMcMurray J see Hawkins N et al

see Jhund P et alsee MacDonald M et alsee Murphy C et al

McVey J see White K et alMead A see Connolly S et alMellad J see Wragg A et alMellander M see Matsui H et alMelton I see Graham L et alMelville M see Alfakih K et alMenick D see Ounzain S et alMent J see Pitt J et alMetcalfe K see Collitt S et alMichalis L see Papafaklis M et alMichelson E see MacDonald M et alMikhail R see Berry C et al

Milborrow G et al. Need for coronary artery bypassgrafting following percutaneous coronary intervention: a single centre UK audit of 2395 revascularisationprocedures, p81

Millane T see Jessani S et alMiller H see Good R et alMills N et al. Ischaemic and thrombotic effects of dilute

diesel exhaust inhalation in patients with coronary heartdisease: mechanisms for the adverse cardiovasculareffects of air pollution, p26

Missouris C see Okonko D et alMitchell A see Dalby M et al

see Hamour I et alMocanu M see Hausenloy D et alMoffitt A see Thornley A et alMoggridge J see Kiotsekoglou A et alMohamed T et al. Plasma membrane calcium atpase

pump isoforms 1 and 4 differentially regulate heartcontractility, p42

Monaco C see Finch J et alMonaghan M see Bhan A et alMongillo M see Cook S et alMoore J et al. Hyperglycaemia reduces endothelial

progenitor cell adherence and differentiation in vitro, p47Moore J see Whittaker A et alMoore M see Hamilton A et alMoore M et al. A study of the effectiveness of public

access defibrillation in urban and rural populations in Northern Ireland: the Northern Ireland Public AccessDefibrillation study, p79

Moreton N see Collitt S et alMorgan M see Ray G et alMorgan-Hughes G see van Lingen R et alMorgenthaler N see Khan S et alMorley R see Tough J et alMorpher M see Kistler P et alMorrell C see Das R et alMorrell N see Lawrie A et alMorris A see Sharman D et al

see Sugden J et alMorris G see Innasimuthu A et alMorris J see Velupandian U et alMorrison L see Mullen M et alMorrow D see Ray K et alMorton A see Siotia A et alMudalagiri N et al. Hypoxic and pharmacolgical

postconditioning protects the human heart by activatingphosphatidylinositol-3kinase, p90

Mudawi T et al. Can unstable arrhythmias be detected by changes in intracardiac impedance?, p72

Muhyaldeen S see Chalil S et alMuir D see Kunadian B et alMullen M see Khan A et alMullen M et al. A prospective, multicentre clinical trial to

evaluate the biostar bioabsorbable septal repair implantfor the closure of atrial level shunts (1-year follow-up), p48

Munir S et al. Effects of inhibition of nitric oxide synthaseon systolic pressure augmentation and conduit arterydiameter, p88

Murphy A see Good R et alMurphy C et al. Iron metabolism is impaired in heart failure

irrespective of haemoglobin concentration and leftventricular ejection fraction, p59

Murphy G see Smith D et alsee White K et al

Murray A see Agarwal S et alMurray G see Pitt J et al

Loh P et al. Heart-type fatty acid binding protein predictsmortality in patients with sinus rhythm and left ventricularsystolic dysfunction, p86

Loo B et al. Atrial fibrillation in a primary care population:how close to NICE guidelines are we?, p39

Lowe M see Ahmed A et alsee Lambiase P et alsee Rogers D et al

Lu H see Sarwar R et alLu H et al. Characterisation of MicroRNAs in the human

heart, p86 Ludman P see DeGiovanni J et alLukaschuk E see Bourantas C et al

see Murphy C et alLyne J see Watkins S et al

MacAllister R see Mwamure P et alMacDonald M see Hawkins N et alMacDonald M et al. The risk associated with diabetes

mellitus in patients with preserved and low ejectionfraction heart failure. An analysis of the Candesartan in Heart Failure: Assessment of Reduction in Mortality and morbidity programme, p59

Transthoracic echocardiography practice in the UK, p85MacDonald S see Graham L et alMacFarlane P see Hajat C et alMacGregor G see Baltabaeva A et alMacintrye P see Ray G et alMacIntyre K see Jhund P et alMacIver D see Townsend M and MacIver D Mackintosh A see Crean A et alMahadeva H et al. Knockdown in Zebrafish supports

important role for myocyte stress 1 in cardiacdevelopment and function, p89

Mahadevan G et al. Prevalence of heart failure preservedejection fraction in the community, p44

Maher A et al. Venoselectivity of nitrite: evidence favouringhypoxic release of nitric oxide, p101

Mahy I see Loo B et alMalik I see Davies J et al

see DeGiovanni J et alsee Hadjiloizou N et al

Malik N see Dhawan A et alManda S see Gale C et alMandal A see Okonko D et alManghat N see van Lingen R et alMangino M see Maznyczka A et alMangion J see Sarwar R et alManisty C see Davies J et al

see Hadjiloizou N et alManisty C et al. Cardiorespiratory control instability

in heart failure: does the chemoreflex show adaptation or are we missing the point?, p44

Differences in the magnitude rather than the timing of wave reflection can explain the ascot results, p88

Mannan I see Roughton M et alMansfield R see Kesavan S et alMarber M see Blows L et al

see Perera D et alMarcheix B see Berry C et alMarciniak A see Marciniak M et al

see Orlando S et alsee Parsai C et al

Marciniak M see Baltabaeva A et alsee Orlando S et alsee Parsai C et al


Author index

114

Lavoie J see Berry C et alLawrence R see Brown B et alLawrie A et al. A potential role for osteoprotegerin in

idiopathic pulmonary arterial hypertension, p46Laws C see Borg A et alLe E see Bragadeesh T et alLeccisotti L see Cook S et alLee J see Shirodaria C et alLefroy D see Martins J et al

see Showkathali R et alLewis K see Haddadin F et alLewis N et al. Is heart failure a process of relentless

progressive ventricular remodelling and functionaldeterioration?, p58

Lewis NT et al. Aging diminishes the pumping capacity of healthy human male but not female hearts, p38

Lewis P see Dhawan A et alLeyva F see Chalil S et al

see Williams L et alLi V see Japp A et alLi W see Khan A et alLim E see Anand D et alLim E et al. Coronary calcification in type 2 diabetes

patients is associated with an increased risk of myocardial ischaemia compared to non-diabetic patients, p74

Lim H et al. Ethnic differences in rates of myocardialinfarction in patients with hypertension are explained by an excess of diabetes, p39

Lim P see Koa-Wing M et alLim S see Simpkin J et alLim S et al. The effect of blood pressure reduction on renal

function in patients with essential hypertension, p103 Lim T see Dwivedi G et al

see Hayat S et alLim T et al. Independent value of left atrial volume

index for the prediction of all cause mortality in patients with suspected heart failure referred from the community, p84

Lin G, Brady P Implantable cardioverter defibrillatorshocks: appropriate versus inappropriate in MADIT IIpatients, p79

Lip G see Jessani S et alsee Lim H et alsee Lim S et alsee Thrall G et al

Lipkin D see Anand D et alLippert M see Mudawi T et alLister A see Thornley A et alLister M see Jani M et alLiu B see Seddon M et alLiu Y et al. Overexpression of hepatocyte growth factor

accelerates mineralisation of human smooth muscle cellsin vitro, p102

Lloyd G see Arya A et alsee Silberbauer J et al

Lo M see Bingham A et alLo T, Nolan J Radial artery diameter, its response to

sublingual GTN and implication for transradial cardiaccatheterisation, p97

Lo T see Freestone B et alLo T et al. Incidence of radial artery anatomical variation in

patients undergoing transradial coronary angiographyand intervention: influence on procedural outcome, p48

Radiation exposure and procedural duration: implications fortransradial and transfemoral coronary angiography, p95

Loh P see Bourantas C et al

117

Perera D see Lo T et alPerera D et al. Coronary collaterals remain recruitable

following percutaneous intervention, p98Perera S see Blows L et alPerry R see Alahmar A et al

see Andron M et alsee Innasimuthu A et al

Peters N see Kirubakaran S et alsee Koa-Wing M et alsee Martins J et al

Petersen S see Ali M et alsee Hudsmith L et al

Peterson R see Ounzain S et alPetretto E see Sarwar R et alPetrie M see MacDonald M et alPezzella F see Jin X et alPfeffer M see MacDonald M et alPhillips H see Henderson D and Phillips H Pillai R see Shirodaria C et alPinto Y see Sarwar R et alPitt J et al. A randomised trial of drug eluting versus

bare metal stents in acute ST elevation myocardialinfarction, p68

Pitt M see Pitt J et alPlein S see Younger J et alPlein S et al. High spatial-resolution myocardial perfusion

MR imaging using K-T sense, p100Iscahemia and scar burden after acute myocardial

infarction, p45Plummer C see Cunnington M et al

see McComb J et alsee McComb J and Plummer C see McComb J and Plummer C

Plummer C et al. An audit of pacing practice in the 33 cardiac networks serving England and Wales, p66

Pollock M see Good R et alPonikowski P see Okonko D et alPoole-Wilson P see Jin X et al

see Okonko D et alPorto I see Selvanayagam J et alPottle A et al. Evaluation of the introduction of

anti-platelet cards for patients post-percutaneous coronary intervention, p104

Powles S see Keeble T et alPradhan D see Boodhoo L et alPrasad R see Keeble T et alPravenec M see Sarwar R et alPrehar S see Cartwright E et alPriestly C see Jani M et alPringle S see Shah N et alPulikal G see Pitt J et alPunjabi P see Cook S et al

see Lu H et alPuntmann V see Orlando S et alPurcell I see Agarwal S et al

see Milborrow G et al

Quinn P see Khan S et al

Radjenovic A see Plein S et alRahimi K see Selvanayagam J et alRahman F see Lu H et alRahman T see Palomino Doza J et alRahman T et al. Association between polymorphic

variation in the endothelin-1 type a receptor gene andambulatory blood pressure, p85

The C-532T polymorphism of the angiotensinogen (AGT)

gene is associated with arterial stiffness: a possibleexplanation for heterogeneity in genetic associationstudies of AGT and hypertension, p88

Raine D et al. Computer-assisted electrical mapping of atrial tachyarrhythmias in patients with surgicallycorrected tetralogy of Fallot, p72

Rajappan K see Kalla M et alsee Kistler P et al

Rajappan K et al. Catheter ablation for permanent atrialfibrillation: are outcomes improved by ablation restoringsinus rhythm without electrical cardioversion?, p40

The impact of linear ablation along the coronary sinus on the outcomes of catheter ablation for permanent atrial fibrillation, p40

Rajwani A see Cubbon R et alRakhit R see Thakaran G et alRamachandra R see Gale C et alRana B see Bhan A et alRanjadayalan K see Sulfi S et alRao G see Innasimuthu A et alRashid R see Perera D et alRatnatunga C see Shirodaria C et alRay G et al. Safety and utility of 0 and 6-hour point of

care troponin testing in low-risk possible acute coronarysyndromes: a district general hospital experience, p80

Ray K et al. Elevated neopterin after acute coronarysyndrome predicts long-term risk of death or non-fatalcoronary events: analysis from prove IT-TIMI 22, p61

Ray S see Borg A et alsee Velupandian U et al

Reddy P see Loh P et alRedpath A see Jhund P et alRedwood S see Blows L et al

see Munir S et alsee Perera D et al

Rees G see Haddadin F et alReeve M see Pitt J et alReeves B see Smith D et alReilly S et al. Is increased myocardial oxidative stress an

early event in the natural history of atrial fibrillation?, p42Richardson G see Gershlick A et alRichmond L see Kistler P et al

see Rajappan K et alRichmond W see Flather M et alRider O see Ali M et alRidgway J see Plein S et al

see Younger J et alRigby A see Khan N et alRitchie L see Haq I et alRobb S see Good R et alRoberts A see Gale C et al

see Turley A et alRoberts E see Alahmar A et al

see Andron M et alRoberts S see Fox D et alRobinson M see Ali M et alRobinson S see Mills N et alRobson M see Ali M et al

see Cheng A et alsee Hudsmith L et alsee Shirodaria C et al

Rogers C see Narayan P et alsee Smith D et al

Rogers D see Ahmed A et alRogers D et al. Improved safety of complex device

implantation can be achieved using simple radiationdose reduction manoeuvres, p79


Author index

116

Murray S see Avlonitis V et alMwamure P et al. Remote ischaemic preconditioning

protects the heart at time of CABG surgery, p26Myerson S see Tomlinson D et al

Nageh T see Keeble T et alNainby J see Alfakih K et alNaji A see Alahmar A et alNarayan P et al. A 15-year audit of acute type

a aortic dissection: have the outcomes changed with time?, p67

Nassiri D see Kiotsekoglou A et alNatarajan A et al. Thrombogenicity in type 2 diabetes

and coronary artery disease, p61Navin T see Finch J et alNegus I see Smith D et alNeubauer S see Ali M et al

see Hudsmith L et alsee Pegg T et alsee Selvanayagam J et alsee Shirodaria C et al

Newby D see Cruden N et alsee Japp A et alsee Lang N et alsee Mills N et al

Newman C see Lawrie A et alNewman W see Collitt S et alNeyses L see Cartwright E et al

see Deepak S et alsee Gupta S et alsee Mohamed T et al

Ng A see Hajat C et alNg L see Gupta S et al

see Kelly D et alsee Khan S et al

Nicholls R see Loh P et alNicklin S see Masson R et al

see White K et alNihoyannopoulos P see Showkathali R et alNikitin N see Loh P et al

see Windram J et alNikitin P see Bourantas C et alNisbet A, Dunn F Indiscriminate use of troponin I

in unselected medical emergencies, p81Nolan J see Freestone B et al

see Lo T et alsee Tan Y et alsee Lo T and Nolan J

Northcote R see Pell J et alNsengimana J see Brown B et alNugara F see Flather M et al

see Stables R et al

O’Brien D et al. Stabilisation of coronary stents using rapid right ventricular pacing, p96

O’Brien R see Khan S et alO’Callaghan P see Willis J et alO’Neill L et al. Nurse-led chest pain triage: meeting the

challenge of acute coronary syndromes, p50 O’Sullivan J see Raine D et alOceandy D see Cartwright E et al

see Mohamed T et alOkonko D et al. Effect of intravenous iron sucrose

on exercise tolerance in anaemic and non-anaemicpatients with symptomatic chronic heart failure and iron deficiency (Ferric-HF): a randomised, controlled,observer-blinded trial, p60

Oldroyd K see Good R et alsee Pell J et alsee Watkins S et al

Omar F see Hamour I et alOrlando S et al. Differentiation between hypertrophic

cardiomyopathy and hypertensive left ventricularhypertrophy: the role of strain rate imaging study andintegrated backscatter analysis, p84

Ormerod O see Arnold J et alOstergren J see MacDonald M et alOunzain S et al. Expression of myocyte stress 1,

a novel gene involved in cardiac development andhypertrophy is regulated by evolutionarily conserved GATA motifs, p90

Oxborough D see Artis N et al

Palin T see Mahadevan G et alsee Maher A et al

Palmer N see Alahmar A et alsee Andron M et al

Palmer T see Maznyczka A et alPalomino Doza J et al. Association between the purinergic

receptors P2X4, P2X6 and P2X7 genetic variation andblood pressure in a British population, p24

Panicker M see Hamour I et alPapafaklis M et al. Association of plaque thickness with

endothelial shear stress in the left main coronary arterybifurcation: in vivo study using 3D reconstruction andcomputational fluid dynamics, p97

Paramanathan A see Hausenloy D et alParker K see Davies J et al

see Hadjiloizou N et alParnell C see Loo B et alParry G see Kirk C et alParsai C see Marciniak M et alParsai C et al. Identifying responders to CRT: are we

using the right method?, p70 Pasquini L see Matsui H et alPatel B see Bingham A et alPatel J see Lim H et al

see Lim S et alsee Yan Y et al

Patel K see Chalil S et alsee Williams L et al

Patel KR see Yan Y et alPatel N see Arya A et al

see Silberbauer J et alPaterson D see Adlam D et al

see de Bono J et alPatwala A see Lewis NT et alPaul V see Williams L et alPegg T see Cheng A et alPegg T et al. Effects of off-pump versus on-pump

coronary artery bypass surgery on early and late right ventricular function as assessed by cardiac MRI, p74

Pell A see Pell J et alPell J et al. Effect of incomplete revascularisation on

outcome following percutaneous coronary interventionfor multi-vessel disease: Scottish CoronaryRevascularisation Register, p26

Pellerin D see Sharma R et alPennell D see Keenan N and Pennell D Penny A see Willis J et alPepper C see Artis N et alPepper J see Jin X et al

see Stables R et al

119

Simpkin J et al. Apelin exhibits cardioprotection againstischaemia reperfusion injury, p90

Singh B see Balachandran K et alSingh J see Dhawan A et alSingh R see Whittaker A et alSiotia A et al. Simultaneous kissing stents (shotgun

stents) to treat left main bifurcation stenosis, p97Sivananthan M see Plein S et al

see Younger J et alSlack R see Pell J et alSlater R see Okonko D et alSmall G see Gibson P et alSmith A et al. Characterisation of the vasodilatory action

of 17ß oestradiol in the human pulmonary circulation, p89Smith C see Hausenloy D et al

see Kabunga P et alsee Simpkin J et al

Smith D et al. Effective radiation dose in angiography ofcoronary artery bypass grafts using multislice computedtomography, p74

Long-term coronary artery bypass graft patency asassessed by multislice computed tomography, quality of life and adverse events in patients randomised to on-and off-pump surgery, p46

Smith E see Keeble T et alSmith E et al. The risk of ventricular arrhythmia

following alcohol septal ablation for hypertrophiccardiomyopathy with symptomatic left ventricular outflow tract obstruction, p97

Smith R see Chalil S et alSmith T see Hajat C et alSmith W see O’Brien D et alSnowdon R see Boodhoo L et alSolomon S see MacDonald M et alSomers K see Crean A et alSouthall E see Loo B et alSouthwood M see Lawrie A et alSparrow P see Plein S et alSpence M see Khan A et alSpiro J see Dalby M et alSporton S see Kalla M et al

see Kistler P et alsee Rajappan K et al

Sprigings D see Descamps M et alSquire I see Kelly D et al

see Khan S et alStables R see Alahmar A et al

see Antony R et alStables R et al. The stent or surgery long-term

follow-up, p25Stanton E see Loh P et alStarkey I see Cruden N et al

see Pell J et alSteedman T see Watkins S et alSteeds R see Edwards N et al

see Whittaker A et alStegemann B see Chalil S et al

see Williams L et alStephenson C see Lewis NT et alStevens S see Gershlick A et al

see Whittaker A et alStewart M see Tough J et alStrange J et al. Evaluation of safety and efficacy of

AngioJet usage in a UK heart attack centre, p82Streather C see Sharma R et alStrickland N see Cook S et alStruck J see Khan S et al

Struthers A see Shah N et alsee Sharman D et alsee Sugden J et alsee Sharman D and Struthers A

Sudhir R see Balakrishnan G et alSugden J et al. Vitamin D improves markers of vascular

health in patients with type 2 diabetes, p89Sulfi S et al. Echocardiography for cardiomegaly identified

in chest x ray: an audit of 625 patients, p99Suliman A see Sulfi S et alSulke A see Arya A et al

see Silberbauer J et alsee Veasey R et al

Suntharalingham J see Lawrie A et alSutherland G see Bajpai A et al

see Baltabaeva A et alsee Kiotsekoglou A et alsee Marciniak M et alsee Orlando S et alsee Parsai C et al

Sutton A see Kunadian B et alSutton G see Roughton M et alSwamydass D see Haddadin F et alSwanson N et al. Late stent thrombosis: long-term

clinical results of the elutes polymer-free drug-eluting stent trial, p69

Swedberg K see Khan N et alsee MacDonald M et al

Swinburn J see Dwivedi G et al

Törnqvist H see Mills N et alTaggart D see Pegg T et alTaggu W see Silberbauer J et alTan J see Khan A et alTan L see Artis N et al

see Lewis N et alTan LB see Lewis NT et alTan Y et al. Lower mortality in acute myocardial infarction

where thrombolysis is administered in the community, p95Tataree D see Tenkorang J et alTaylor A see Coats L et alTenkorang J see Thakaran G et alTenkorang J et al. A report on the referral rate of patients

seen in a rapid access chest pain clinic for endoscopy: are we creating work for our colleagues?, p67

Teoh M see Dalby M et alThain A see Keeble T et alThakaran G et al. Clinical pre-test probability is superior

to exercise-testing as a tool for identifying the highest risk patients: data from a rapid access chest pain clinic, p81

Theodorakis P see Papafaklis M et alThillainayagam A see Tenkorang J et alThom S see Manisty C et alThomas D see Willis J et alThomas S see Haddadin F et alThompson J see Whittaker A et alThompson M see Kelly D et alThompson P see Bowater S et alThorne S see Bowater S et alThornley A see Kunadian B et al

see Tough J et alsee Turley A et al

Thornley A et al. Cardiac rehabiilitation and patienteducation following primary percutaneous coronaryintervention, p49

Thornley R see Kunadian B et al


Author index

118

Simple dose limitation manoeuvres can significantly reduce radiation exposure dose during radiofrequencyablation, p40

Roobottom C see van Lingen R et alRosenzweig A see Cook S et alRothman M see Strange J et alRoughton M see Dalby M et al

see Matsui H et alsee Okonko D et al

Roughton M et al. Long-term survival of patients with a new diagnosis of heart failure: a population based prospective cohort study, p91

Rowland E see Bajpai A et alRubens M see Flather M et alRuperalia N see Dwivedi G et alRussell S see Ray G et alRyding A see Descamps M et al

see Tomlinson D et alRyding A et al. Troponin elevation in non-acute

coronary syndromes: OXVASC data, p62Ryf S see Plein S et al

Söderberg S see Mills N et alSabatine M see Ray K et alSabharwal N see Tomlinson D et alSaha M see Perera D et alSamani N see Bingham A et al

see Hajat C et alsee Kelly D et alsee Mahadeva H et alsee Maznyczka A et alsee Moore J et alsee Ounzain S et alsee Whittaker A et al

San H see Wragg A et alSandher R see Smith A et alSandilands A, Cripps T The use of amiodarone in

implantable cardioverter defibrillator patients, p78 Sandilands A et al. Single centre UK experience of

cryoablation balloon for paroxysmal atrial fibrillation, p39Sandman H see Chalil S et alSandström T see Mills N et alSapsford R see Cubbon R et alSarwar R et al. Integrated genetic linkage analysis and

expression profiling in the rat heart to identify primarydrivers of cardiac hypertrophy, p24

Sassard J see Bingham A et alSattar N see Murphy C et alSavelieva I see Bajpai A et alSavelieva I et al. Heart rate lowering action of ivabradine

depends on baseline heart rate: mechanism of lowincidence of excessive bradycardia during therapy withivabradine, p62

Schilling R see Kalla M et alsee Kistler P et alsee Rajappan K et alsee Rajappan K et al

Schlosshan D see Lewis N et alSchotten U see Reilly S et alSchroen B see Sarwar R et alSchwitter J see Plein S et alSciberras P see Koa-Wing M et alSeale A see Matsui H et alSearle N see Cheng A et alSeddon M et al. Effects of glyceryl trinitrate to lower

central arterial pressure relate to arterial vasodilationrather than reduction in preload, p49

Sekhri N see Zaman M et alSelvanayagam J see Cheng A et al

see Pegg T et alSelvanayagam J et al. Effect of distal embolisation

on myocardial perfusion reserve following percutaneouscoronary intervention: an quantitative MR perfusion study, p82

Senior R see Dwivedi G et alsee Greaves K et alsee Hayat S et alsee Hickman M et alsee Jeetley P et alsee Lim T et alsee Wennicke N et al

Sethi J see Ezzat V et alSevant D, Khokhar A Audit of rate of recurrence of atrial

fibrillation following DC cardioversion, p49Shah A see Basavarajaiah S et al

see Ezzat V et alShah N et al. Evidence for a strong antiarrhythmic effect

of spironolactone in patients with coronary artery disease but without heart failure, p62

Sharma R et al. Myocardial deformation imaging for the prediction of subclinical left ventricular dysfunction and mortality in asymptomatic patients with end stagerenal disease and normal left ventricular ejection fraction, p84

Sharma S see Basavarajaiah S et alsee Greaves K et al

Sharman D, Struthers A Chronic heart failure patients on lisinopril versus ramipril therapy exhibit no difference in the reactivation of vascular tissue angiotensin I toangiotensin II conversion, p103

Sharman D et al. Type 2 diabetics on chronic lisinopriltherapy exhibit gradual reactivation of vascular tissueangiotensin I to angiotensin II conversion, p103

Sharp L see Lewis NT et alShaw M see Alahmar A et al

see Andron M et alShaw S see Fox D et al

see Mahadeva H et alSheppard M see Lambiase P et alShetty A see Smith E et alShiang-Yong L see Hausenloy D et alShiang-Yong L et al. Preconditioning and

postconditioning: the mitochondrial permeablitytransition pore as the common end-effector, p43

Shirodaria C see Arnold J et alsee Tomlinson D et al

Shirodaria C et al. Improvement in vascular function withlow-dose folic acid supplementation: implications forfolate therapy and dietary fortification, p90

Showkathali R et al. Success and clinical outcome ofcatheter ablation for supraventricular tachycardia inpatients with severe pulmonary hypertension withoutcongenital heart disease: a case series report, p103

Shufflebotham A see Freestone B et alShui A see Ray K et alSigwart U see Stables R et alSilberbauer J see Arya A et al

see Veasey R et alSilberbauer J et al. AF may beget AF but does PAF

beget PAF?, p94Quantification of cardiac dyssynchrony at rest and after

peak exercise in heart failure patients, p70Silver L see Ryding A et alSimon R see Rogers D et al

121

Woodburn K see Sandilands A et alWork L see Masson R et al

see White K et alWragg A et al. Genetic lineage tracking of haematopietic

cells using the Cre/Lox system to investigate the role of endothelial progenitor cells in normal vasculardevelopment and after vascular injury in mice, p100

Wright G et al. CT attenuation correction of SPECTmyocardial perfusion scintigraphy improves diagnosticaccuracy, p99

Wright M see Koa-Wing M et alWright R see Kunadian B et alWrightson N see Kirk C et alWynne A see Hausenloy D et al

see Simpkin J et al

Yan Y et al. Are cardiologists immortal?, p95 Yellon D see Hausenloy D et al

see Mudalagiri N et alsee Mwamure P et alsee Shiang-Yong L et alsee Simpkin J et al

Yen Ho S see Kistler P et alYin D see Brady A et alYounger J see Plein S et alYounger J et al. Demonstration of coronary venous

anatomy using cardiac MRI, p73 The feasibility of whole heart magnetic resonance

coronary angiography to determine the course of anomalous coronary arteries, p73

Troponin-I concentrations 72 h after myocardial infarction are a reliable predictor of infarct size and microvascular obstruction: a CMR imaging study, p99

Yousef Z see Willis J et alYusuf S see MacDonald M et al

Zacharias K see Balakrishnan G et alZaman A see Lo T et al

see Natarajan A et alZaman M et al. Are there ethnic differences in the

diagnostic and prognostic value of angina symptomdescriptors? A 3-year prospective study of 2189 South Asians, p27

Zambanini A see Manisty C et alZhang M see de Bono J et al

see Reilly S et alZi M see Cartwright E et al


Author index

120

Thrall G et al. Prevalence of depression and anxietyamong patients with atrial fibrillation: effects on 6-monthquality of life, p54

Timmis A see Sulfi S et alsee Zaman M et al

Timperley J see Tomlinson D et alTin L see Loh P et alTobin M see Hajat C et al

see Maznyczka A et alTodd D see Boodhoo L et alTomlinson D et al. Manual assessment of QRS duration:

importance of ECG format and clinical implications in light of NICE ICD implantation guidelines, p38

Thromboembolism risk reduction in patients undergoingcatheter ablation procedures for persistent andparoxysmal atrial fibrillation: a comparison of UK andinternational protocols, p40

Toner P et al. Training basic life support to school children using medical students and teachers in a ‘‘peer-training’’ model: results of the ‘‘ABC for life’’ programme, p55

Torabi A see Khan N et alTough J et al. Rapid access chest pain clinic referrals

for angiography: room for improvement?, p96Toumpanakis C see Bhattacharyya S et alTownend J see Edwards N et alTownsend M, MacIver D Is diastolic heart failure

a myth?, p44 Tracey I see Lim H et alTurley A et al. A novel score based on age and cardiac

biomarkers predicts outcomes in severe sepsis and septic shock, p83

see Thornley A et alsee Tough J et al

Tweddel A see Bourantas C et alsee Wright G et al

Tyler D see Hudsmith L et al

Uddin M see Ahmed A et alUrdahl H see Brady A et al

van Gaal W see Arnold J et alsee Selvanayagam J et al

van Lingen R et al. Negative multidetector coronary CTA in symptomatic patients confers a good one-yearprognosis, p46

Varyani F see MacDonald M et alVasa M see Moore J et al

see Whittaker A et alVeasey R see Arya A et al

see Silberbauer J et alVeasey R et al. Electrophysiological characteristics of

symptomatic atrial fibrillation, p94Velupandian U et al. Patent foramen ovale: an evaluation

of different diagnostic techniques and routes of contrastadministration, p85

Role of modified valsalva manoeuvre in the diagnosis of patent foramen ovale by transoesophagealechocardiography, p58

Vichare S see Mwamure P et alVijayalakshmi K see Kunadian B et alVink E see Mills N et alvon Zglinicki T see Collerton J et alVrahimides J see Arya A et alVrapi F et al. Cardiovascular mortality in dialysis

patients, p67 Vrapi F see Kabunga P et al

Wainwright J see Butler R and Wainwright J Waktare J see Boodhoo L et alWalji S see Greaves K et alWallace D see Koa-Wing M et alWalsh J see Alfakih K et alWaterall J see Alfakih K et alWatkins H see Hudsmith L et al

see Imrie H et alsee Rahman T et al

Watkins S et al. Can false positive and negative first pass myocardial perfusion MRI scans be explained by coronary physiological measurements?, p45

Waywell C see Gupta S et alWeaver R see Mahadevan G et alWebb G see Willis J et alWeerasinghe A see Balakrishnan G et alWennicke N et al. Stress echocardiography in the district

hospital setting: a cost-effectiveness analysis, p70West N see Johnson T et al

see Wheeler S et alWestaby S see Arnold J et al

see Jin X et alWeston C see Gale C et alWheatcroft S see Crean A et al

see Cubbon R et alsee Ezzat V et al

Wheeler S et al. Does the Levine sign aid diagnosis of angina in a rapid-access chest pain clinic?, p67

Whinnett Z see Davies J et alsee Manisty C et al

White K et al. Development and characterisation of viralvectors targeted to atherosclerotic plaques, p101

Whitlam H see Pitt J et alWhittaker A see Maznyczka A et al

see Moore J et alWhittaker A et al. Elevated circulating endothelial

progenitor cells in healthy adult offspring of subjects with coronary artery disease, p101

Endothelial progenitor cells in adults with and withoutcoronary artery disease and their healthy adult offspring:evidence for potential genetic regulation, p25

Heterozygous carriage of the Klotho Kl-VS allele isassociated with reduced risk of myocardial infarction, p90

Wilkinson F see Liu Y et alWilliams G see Artis N et alWilliams L see Mahadevan G et alWilliams L et al. Left ventricular reverse remodelling

after cardiac resynchronisation therapy in heart failurepatients with a narrow QRS duration, p59

Williams S see Fox D et alWillis B see Koa-Wing M et alWillis J et al. Long-term left ventricular lead stability

during biventricular pacing, p93Willson K see Manisty C et alWilson J see Gale C et alWilson K see Bhan A et alWilson M see Basavarajaiah S et alWindram J see Loh P et alWindram J et al. The effect of growth hormone upon

cardiac function and exercise capacity in patients with adult onset growth hormone deficiency, p100

Witham M see Sugden J et alWitkowski T see Okonko D et alWood D see Connolly S et al

see Martins J et alsee Roughton M et alsee Tenkorang J et al


Conference floor plan FIRST FLOOR

ENTRANCE

ENTRANCE

KEY REFERENCE

ENTRANCE

TO CLYDE AUDITORIUM, FORTH AND GALA ROOMS,

AND HOTEL

CO

NC

OU

RS

E

CO

NC

OU

RS

E

DOCHART CARRON

LOMOND

LOMOND

BOISDALE ALSH

LEVEN

NESS

FYNE ETIVE

MORAR

KATRINE

HALL 3

HALL 4HALL 2

HALL 1

HALL 5

CO

NC

OU

RS

ELOMOND

BOISDALE ALSH

FYNE ETIVE

CONFERENCECENTRE

(CLYDE, FORTH AND GALA ROOMS)

HALL 1

FIRSTFLOOR

GROUND FLOOR

TO CLYDE AUDITORIUM, FORTH AND GALA ROOMS,

AND HOTEL

CO

NC

OU

RS

E

DOCHART CARRON

LOMOND

LEVEN

NESS MORAR

KATRINE

KEY TO MAPS

1 Inset 1 ABode Hotel2* F3 2 Alona Hotel1 D1 3 Ambassador Hotel1 D2 4 Angus Hotel1 D2 5 Argyll Hotel1 Inset 6 Artto Hotel2* D2 7 The Beardmore Conference Hotel2* F3 8 Best Western Popinjay Hotel1 Inset 9 Bewleys Hotel1 D3 10 Campanile1 Inset 11 Carlton George Hotel1 Inset 12 City Aparthotel Glasgow1 Inset 13 City Apartments Glasgow1 D3 14 City Inn Glasgow1 Inset 15 Corus Hotel Glasgow1 D3 16 Crowne Plaza Glasgow2* F2 17 Crowwood House Hotel2* F3 18 Dalziel Park Hotel & Conference Centre2* D1 19 De Vere Cameron House Hotel & Resort1 D3 20 Devoncove Hotel2* D2 21 Erskine Bridge Hotel1 E3 22 Euro Hostel2* D2 23 Express by Holiday Inn – Glasgow Airport1 F3 24 Express by Holiday Inn – Riverside2* F3 25 Express by Holiday Inn - Strathclyde1 Inset 26 Express by Holiday Inn – Theatreland1 F3 27 Fraser Suites Glasgow2* D2 28 Glynhill Leisure Hotel1 Inset 29 Hilton Glasgow1 D2 30 Hilton Glasgow Grosvenor2* E3 31 Holiday Inn – East Kilbride2* D2 32 Holiday Inn Glasgow Airport1 Inset 33 Holiday Inn Glasgow City West1 Inset 34 Holiday Inn Glasgow Theatreland1 Inset 35 Ibis Hotel1 E3 36 Jurys Inn Glasgow1 Inset 37 Langs Hotel2* C1 38 Lodge on Loch Lomond2* E3 39 MacDonald Crutherland House1 Inset 40 Malmaison Glasgow2* D2 41 Mar Hall Hotel1 Inset 42 Marriott Glasgow1 Inset 43 Menzies Glasgow Hotel1 Inset 44 Millennium Hotel Glasgow2* D2 45 Normandy Hotel1 Inset 46 Novotel Glasgow Centre1 C1 47 One Devonshire Gardens2* D4 48 Park Hotel1 C1 49 Pond Hotel1 Inset 50 Premier Travel Inn Glasgow (Charing X)1 Inset 51 Premier Travel Inn Glasgow (George Sq)1 Inset 52 Quality Hotel Central1 Inset 53 Radisson SAS2* D2 54 Ramada Glasgow Airport1 Inset 55 Ramada Glasgow City1 D4 56 The Sherbrooke Castle Hotel

Map Grid Ref Name of VenueNo. Ref No.

Map Grid Ref Name of VenueNo. Ref No.

HOTELS 1 Inset 57 The Spires2* D2 58 Swallow Gleddoch House and Golf Club1 C4 59 Swallow Hotel1 Inset 60 Thistle Glasgow2* C4 61 Thistle Irvine1 F4 62 Tulip Inn2* F2 63 The Westerwood

2* E2 64 Braehead Arena2* D2 65 Glasgow Audi Conference & Event Centre1 Inset 66 Glasgow City Halls2* D2 67 Reid Macewen Conference & Training Centre1 Inset 68 Glasgow Royal Concert Hall1 D3 69 Scottish Exhibition & Conference Centre1 E3 70 The Teacher Building

1 C1 71 Acanthus1 E3 72 The Arches1 Inset 73 Arta2* D2 74 Auchentoshan Distillery1 F3 75 The Barony - University of Strathclyde1 C5 76 The Burrell Collection1 Inset 77 CCA1 Inset 78 Corinthian2* C1 79 Cruise Loch Lomond2* D2 80 Erskine Sports Centre1 Inset 81 Gallery of Modern Art1 Inset 82 Glasgow Opportunities1 Inset 83 Glasgow School of Art1 D3 84 Glasgow Science Centre2* E1 85 Glengoyne Distillery1 C4 86 House for an Art Lover1 D2 87 Kelvingrove Art Gallery and Museum2* D2 88 Lagoon Leisure Centre1 Inset 89 The Lighthouse1 Inset 90 Metropolitan Cocktail Bar & Restaurant1 D2 91 Museum of Transport1 D2 92 OranMor2* D3 93 Paisley Abbey2* D3 94 Paisley Art Centre2* D3 95 Paisley Museum & Art Galleries2* D3 96 Paisley Town Hall1 Inset 97 Royal Scottish Academy of Music and Drama1 E4 98 Scotland Street School1 F3 99 St Mungo Museum1 C3 100 The Tall Ship at Glasgow Harbour1 Inset 101 Tiger Tiger1 Inset 102 Trades Hall of Glasgow1 F4 103 West Brewing Company1 F4 104 Winter Gardens and People's Palace

1 Inset 105 Glasgow Caledonian University1 D2 106 Glasgow University Union1 D2 107 University of Glasgow1 Inset 108 University of Strathclyde

PURPOSE BUILT VENUES

UNUSUAL VENUES

ACADEMIC VENUES

60

3426

37

91

1350

12

57

33

643

47

49

30

20

62

27

2224

36

59

56

5

3

4

71

9187

100

84

72 70

76

86

98

7599

92

42

53

55

97

101

105

108

106

107

102

103104

90

66

68

73

78

83

81

82

77

89

51

4411

52

15

29

4635

40

10

69

16

14

SECC


Area map of Glasgow

annualscientific 2007 - british cardiovascular society programme 2007.pdfbritish cardiovascular...

Documents