anterpartum haemorrhage

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    Clinical cases Case 1 I am 38 wee s pregnant and bleeding

    !aginall" #A 2$ "ear old woman attendsthe midwi%e at 38 wee s gestation # &hehad pre!ious uncomplicated deli!eriesand she is concerned that o!er the past%ew da"s she has been ha!ing a smallamount o% %resh !aginal bleedingintermittentl"# &he has no abdominal painand the bab" is acti!e#

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    Diferential diagnosis

    'lacenta prae!ia 'lacental abruption Cer!ical lesions ( erosion)pol"p)cancer*

    History to supportdiagnosis 'ainless small bleeds

    supports diagnosis o%placenta prae!ia#

    Additional patient+ssmear histor" shouldbe obtained# ,hereport o% an" pre!ious

    -&&s in this pregnanc"should be chec ed inorder to identi%" thelocation o% placenta#

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    Clinical examination

    Abdominal palpation

    .etal heart sound

    auscultated &peculum e/amination o digital e/amination

    Reasons o clinicalexamination &upport '' palpation) with

    a so%t non tender uterus mhigh presenting part and anabnormal lie

    to e/clude %etal distress( ass placenta abruption*

    I% placenta is not low b"-&&) to !isuali e the cer!i/indicated#

    ,orrential bleeding can bepro!o ed i% '' has been%alsel" e/cluded as a cause

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    In!estigations

    .BC Blood group and cross

    match 4leihaur test i%rhesus negati!e

    -&& C,5

    ,o detect anemia In case bleeding increases

    and a trans%usion is re6uired# ,he patient should be gi!enanti 7 i% her blood group isrhesus negati!e to pre!entisoimmunisation

    ,o locali e the placenta and

    determine whether it is lowl"ing )as well as to assess%etal growth and well being#

    ,o identi%" suspected %etalcompromise

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    Management Admit patient to an obstetric unit# At term gestation with a histor" o%

    A' )deli!er" is indicated to ensure a sa%e deli!er" o% a mature %etus# Caesarean section should be pre%ormed in cases o% ma9or placenta prae!ia Consider e/amination without anesthesia and arti:cial rupture o%

    membranes in cases with minor degrees o% ''# ,his procedure should be

    per%ormed in an operating theater with a senior anesthetist present andread" to administer a general anesthesia to e/pedite deli!er" i% bleeding ispro!o ed on !aginal e/amination#

    Cross matched blood should be a!ailable in ;, and can per%orm animmediate C sec i% indicated

    I% diagnosis o% placental abruption is suspected ( based on the low l"ingplacenta on scan )normal appearance o% the cer!i/ on speculum< Andthere is no e!idence o% %etal compromise) an arti:cial ruptures o%membrane should be per%ormed and an o/"tocin ( &"ntocinon* in%usioncommended with continuous monitoring o% the %etal heart because o% theincreased ris o% %etal h"po/ia#

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    =is s o% Antepartumhaemorrhage

    emorrhage and shoc =enal %ailure

    7isseminated intra!ascularcoagulation(7IC* .etal h"po/ia

    Intrauterine death

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    Case 2 I am 32 wee s pregnant and ha!ing contractions A 2> "ear old nulliparous woman at 32 wee s

    gestation presents with abdominal pain associatedwith uterine contractions# .etal mo!ements aresatis%actor"# er boo ing ultrasound scan (-&&*showed singleton pregnanc" consistent withmenstrual dated and her anomal" scan at 20 wee sgestation was normal# er screening %or 7own+s

    &"ndrome was reported ad low ris # &he had beena smo er but stopped in mid trimester# &he had anappendectom" as a child# &he was assessed to be alow ris pregnanc" at boo ing

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    7i?erential diagnosis

    Obstetric causes

    're term labor Chorioamnionitis Concealed abruptio

    placenta .ibroid degeneration

    ( usuall" at midtrimester*

    Non obstetric causes

    -rinar" tract in%ection)p"elonephritis ( canprecipitate pre termlabor*

    Irritable bowels"ndrome)constipation

    ;!arian c"st( hemorrhage) torsion*

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    A , 'A=,-M

    M;== A5

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    7 .I I,I;

    Antepartum haemorrage Bleeding %rom the genital

    tract %rom 22 nd wee o%pregnanc" or

    %oetal weight is more than>00 grams

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    CA-& &

    Diagnosis Clinical ndings

    Placenta previa Bleeding P ! painless

    "bruptio placenta #revealed$ Bleeding P ! Pain abdomen!tender abdomen

    "bruptio placenta#concealed$

    Bleeding P ! pain abdomen!tender abdomen! %&H mig'tbe more t'an PO( #approx)*+cm$

    asa previa Bleeding P ! painless

    ,xcessive s'o- Bleedin P ! .abor pain #/0*$!cervical os dilated1

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    ' AC ,A '= IA

    'lacenta which issituated wholl" orpartiall" within thelower segment ator a%ter 28 wee s o%gestation#

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    C A&&I.ICA,I;

    2ype 3lo- lying placenta*

    implanted in lo-er uterinesegment1 ,dge o placentais near t'e internal os but

    not reac' it

    2ype )marginal placenta*located

    at t'e margin o t'einternal os

    2ype +partial placenta previa!-'en placenta partially

    covering t'e internal os

    2ype 4*

    total placenta

    previa!placentacom letel coverin t'e

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    P."C,N2" PR", 5"

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    '= 7I&';&I 5 .AC,;=&

    "bnormal placental implantation "dvanced maternal age #6+7years are + times

    more li8ely to 'ave placenta previa$ 9ultiparity : 7; in grand multiparous patients 9ultiple gestation Previous abortion Previous caesarean section %mo8ing Prior placenta previa #4*

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    M C A I&M ;. B 7I 5

    (ro-t' o placenta slo-sdo-n cause t'e dilatation o

    lo-er segment and inelasticplacenta is s'ared of t'elo-er segment -all1 2'is

    leads to opening o utero*placental vessels and causest'e episode o bleeding

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    7IA5 ;&I& I&,;= aginal bleeding occurs suddenly

    during t'e t'ird trimester Bleeding is usually brig't red

    and painless 5nitial bleeding is not usually

    pro use but it is 8no-n to recur 2'e rst bleed usually occurs at

    )=*+) -ee8s o gestation Contraction may or may not

    occur simultaneously -it' t'e

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    AB;=A,;= &,-7I & &ull blood count : 'emoglobin

    estimation (roup! screen and 'old or at least 4

    units o blood &ibrin split products #&%P$ and

    brinogen level Prot'rombin time #P2$0 activated

    partial t'romboplastin time #aP22$ "P2 test to determine etal origin o

    blood #as in t'ecase o vasa previa$

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    IMA5I 5 &,-7I & 2rans abdominal sonograp'y

    " simple! precise and sa e met'od to visuali>e t'eplacenta

    Have an accuracy o ?7; &alse positive can occur secondary to ocal uterine

    contractions or bladder distension1

    2rans vaginal sonograp'y %a er and more accurate t'an trans abdominal met'od ,specially -'en it comes to t'e diagnosing type 3 and )

    placenta previa

    9R5 @se ul in determining placenta accreta1 But is not a cost

    efective diagnostic tools

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    C;M' ICA,I; & PPH 5ntrauterine gro-t' retardation

    #5@(R$ Congenital anomalies &etal anemia and R'

    isoimmuni>ation 9aternal mortality due to

    'emorr'age

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    MA A5 M , If the Pregnancy less t'an +=-ee8s

    No active bleeding 9ot'er -it' Hb is 63Agm; &etal -ell being assured* &H% by

    C2(! @%(, P,C2"N2 9"N"(,9,N2#9aca ee Conservative

    9anagement$

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    C; & = A,I MA A5 M ,(McCa%ee+s =egime*

    itals are monitored in t'e -ard @%( monitoring or locali>ation o

    placenta is done every ) -ee8s toloo8 or placental migration -'ic' isa possibility prior to +4- since t'elo-er segment ormation is in t'eprocess o completion

    &etal monitoring by C2( andbiop'ysical pro ling s'ould be doneto ensure etal -ell being1

    Eeep a daily etal movement countc'art

    ) doses o Dexamet'asone #3)mg$

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    CA &A= A & C,I; If the Bleeding occurs at or a ter

    +=-ee8s o pregnancy Pt is in labour Bleeding persists #pro use

    'emorr'age and pt 'as'ypotension and ot'er eatureso s'oc8$

    5mmediately delivery t'e etusby C%

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    Cont 5 pro use bleeding occur!

    'emodynamic stability o t'e patients'ould be addressed rst1

    ,stablis'ment o ) large* bore 5access lines -it' 5 crystalloids orblood products

    @rinary cat'eteri>ation is done -it'&oley s Cat'eter

    Blood is ta8en or investigation "nemia treated -it' blood

    trans usion

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    2GP, 3 #"N2,R5OR PO%2,R5OR$

    Can deliver vaginally9ore li8eli'ood o etaldistressin post type -'en t'elo-est edge o t'e placenta isalmost reac'ing t'e internalos margin

    2GP, 55 "N2,R5OR Can deliver vaginally

    2GP, 55 PO%2,R5OR C*section I as -'en t'e 'eadenters t'e pelvis! it impactson t'e placenta -'ic' islocated posteriorly againstsacrum1.ead to uteroplacentalinsuJciency and etal'ypoxia and distress

    2GP, 555 #"N2,R5OR PO%2,R5OR$

    C*section"nterior is more dangeroussince obstetrician 'as to cutt'roug' t'e placenta todeliver baby and it 'as to be

    ast and eJciently done

    2GP, 5 "bsolutely C*section

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    AB=-',I; ' AC ,A

    Prematureseparation o normallyplaced placenta a ter)A -ee8s o gestationand prior to t'e birt'o t'e in ant1

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    '= 7I&';&I 5 .AC,;=& 9aternal H2N 9aternal trauma #motor ve'icle accident!

    asault! alls$ Cigarette smo8ing "lco'ol consumption Cocaine use %'ort umbilical cord

    %udden decompression o t'e uterus Retroplacental broid "dvanced maternal age 5diopat'ic

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    "BR@P25O P."C,N2"

    'remature separation o% the normally implanted

    placenta

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    C A&&I.ICA,I; C."%% A

    "symptomatic &inding an organi>ed blood clot and depressed

    area on a delivered placenta

    C."%% 3 @pto mild vaginal bleeding 2ender uterus

    Normal maternal BP and 'eart rate No coagulopat'y No etal distress

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    C."%% ) @pto moderate vaginal bleeding %evere uterine tenderness -it' possible tetanic

    contractions 9aternal tac'ycardia -it' ort'ostatic c'anges in BP

    and 'eart rate &etal distress Hypo brinogenemia

    C."%% + @pto 'eavy vaginal bleeding ery pain ul tetanic uterus 9aternal s'oc8 Hypo brinogenemia Coagulopat'y &etal deat'

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    'A, ;' &I; ;5 Presence o blood in t'e decidua basalis

    lead to separation o placenta Hematoma ormed causes urt'er

    separation o placenta .eading to compression o placenta andcompromise t'e uteroplacental per usion

    Retroplacental blood later penetrate

    t'roug' t'e t'ic8ness o t'e uterine -allinto t'e peritoneal cavity 2'is p'enomenon is 8no-n as Couvelaire

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    9yometrium in t'is area become-ea8ened

    9ay give a-ay and rupture -it'increased intrauterine pressureduring contraction

    Can cause etal 'ypoxia

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    & M',;M& aginal bleeding "bdominal or bac8

    pain &etal distress "bnormal uterine

    contractions

    Preterm labor &etal deat'

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    C;M' ICA,I; & 9O2H,R

    Hemorr'agics'oc8

    Coagulopat'y0D5C

    @terine

    rupture Renal ailure 5sc'aemic

    necrosis odistal organs

    &,2@% Hypoxia "nemia (ro-t'

    restriction

    CN% anomalies &etal deat'

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    AB;=A,;= &,-7I & Hemoglobin! 'ematocrit! platelets Prot'rombin time 0 activated partial

    t'romboplastin time &ibrinogen! brin0 brinogen

    degeneration products D*dimer

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    7I.. = ,IA 7IA5 ;&I& Blunt abdominal trauma "cute appendicitis Disseminated intravascular

    coagulation Ovarian torsion

    Placenta previa ,ctopic pregnancy Hemorr'agic s'oc8

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    ,= A,M ,&

    "ssess : Blood .oss 9aturity o &etus

    K'et'er s'e is in labor %end 5nvestigations %ecure 5 line 9onitor maternal etal

    condition

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    A&A '= IA

    2'e etal blood vessels traverse t'e

    .@% in advance o presenting part in

    close proximity to t'e inner cervical os 2'ese vessels traverses -it'in t'e

    membrane Not supported by umbilical cord or

    placental tissue putting t'em at ris8 orupture -'en t'e supportingmembrane rupture

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    'A, ;' &I; ;5 2'e vessels may arise rom a

    velamentous insertion o t'eumbilical cord or may be Loiningan accessory placental lobe tot'e placenta

    Occur -'en t'ese etal vesselsrupture and t'e bleeding is rom

    etoplacental circulation .ead to etal exsanguination and

    deat'

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    7IA5 ;&I& Clinically Present o painless vaginal bleeding at t'e

    time o spontaneous rupture o membraneor amniotomy1

    &etal bradycardia depend on rapidity o t'e'emorr'age

    Can lead to etal s'oc8 or deat'

    9ost o ten t'e etus is already dead -'ent'e diagnosis is made because t'e bloodloss constitutes a maor bul8 o bloodvolume o t'e etus1

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    MA A5 M , A 7 ,= A,M ,&

    Obstetrician must be vigilant -'eneveramniotomy is per ormed!as all cases o vasaprevia cannot be identi ed antenatally

    5mmediate delivery s'ould be consideredand aggressive resuscitation o t'e neonate

    Necessary to avoid etal s'oc8 or demise-'en vaginal bleeding occur during labour1

    ,mergency caesarean section stronglyconsidered or t'e rst sign o bleeding

    ollo-ing amniotomy associated -it' etaldistress

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