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    39-49.837,$:70739-49.837,$:707

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    438/07,9438339-49.%07,5438/07,9438339-49.%07,5

    22:3089,9:841905,90398489/01038022:3089,9:841905,90398489/010380

    .74-444147,310.9438.74-444147,310.9438

    !,9039,880882039!,9039,880882039

    39-49.907,539-49.907,5 %07,50:9.!745,.9.%07,50:9.!745,.9.

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    22:30$9,9:841905,9039822:30$9,9:841905,90398

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    22:30$9,9:841905,9039822:30$9,9:841905,90398

    489010380489010380

    22:39,,389397,47,22:39,,389397,47,

    310.9438/0503/,3943310.9438/0503/,3943

    :247,22:3070854380:247,22:3070854380

    00/,90/22:307085438000/,90/22:3070854380

    4.,1,.9478322:30708543804.,1,.9478322:3070854380

    !74-02894304190,-4;0!74-02894304190,-4;020.,38284:/3.70,8020.,38284:/3.70,809090549039,147310.943549039,147310.943

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    .74-44.74-4417,310.943817,310.9438

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    48947,310.9438,7020/3473.4388934148947,310.9438,7020/3473.43889341

    ,074-.,3/,3,074-.7,25489;0,3/7,230,9;0,074-.,3/,3,074-.7,25489;0,3/7,230,9;0

    47,382847,3828

    3,074-08570/423,393,074-08570/423,39

    .74-4417,310.9438.74-4417,310.9438

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    %0950841-,.907,3/039,%0950841-,.907,3/039,

    310.9438310.9438

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    !,9039880882039!,9039880882039

    42509020/.,894742509020/.,8947

    ,23,94341900,/,3/30.7043,23,94341900,/,3/30.7043

    0907230905,903980,989,9:80907230905,903980,989,9:8 $8902..438/07,9438$8902..438/07,9438

    0,79/80,8030:974503,85030.942/,-0908209:803/0,79/80,8030:974503,85030.942/,-0908209:803/89,0703,/80,8047,397,385,39'310.943949,43989,0703,/80,8047,397,385,39'310.943949,439705,.02039,3/490725,390//0;.0805,9./81:3.943705,.02039,3/490725,390//0;.0805,9./81:3.943

    5703,3.5703,3.

    894741,/;0780/7:70,.9438894741,/;0780/7:70,.9438

    !49039,/7:!49039,/7:/7:3907,.9438/7:3907,.9438

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    !,9039,880882039147,39-49.970,92039!,9039,880882039147,39-49.970,92039

    /03914.,,3/4788902.838,3/825942894/03914.,,3/4788902.838,3/8259428948:5547990/,348841310.9438:5547990/,348841310.943

    4.,83841310.9434.,83841310.943

    7902,,7298035,37902,,7298035,3 ,,8010;07.8,,8010;07.8

    488411:3.943488411:3.943 /85,,9782:8/8530,/85,,9782:8/8530,

    $8902.83841310.943$8902.83841310.943

    !!

    #!#!

    &7304:95:9&7304:95:9

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    ,3488417,310.9438,3488417,310.9438

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    ,.907,310.943419047,.,;9,.907,310.943419047,.,;9

    !07,5.,!074/439,!07.4743,!4898:7.,!07,5.,!074/439,!07.4743,!4898:7.,

    ,-03,80,-03,80/030,90/801/030,90/801293.43/943293.43/943 !49039,948570,/,3/708:93,2,471,8.,85,.0310.943!49039,948570,/,3/708:93,2,471,8.,85,.0310.943

    1010970,9033806:0,0.,3038:0970,9033806:0,0.,3038:0

    $059.02,$059.02,

    :/8,33,:/8,33,

    ,;0734:883:89742-488,;0734:883:89742-488

    7,4-897:.9437,4-897:.943

    0/,893980/,89398

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    %70,92039417,310.9438%70,92039417,310.9438

    #024;090.,:8041310.943#024;090.,:8041310.943 $5439,304:8$5439,304:8

    $:7.,/7,3905:8$:7.,/7,3905:8

    ,.,85,.0310.9438,.,85,.0310.9438

    $03/905:88,250147.:9:70,3/80389;90,22.74-44$03/905:88,250147.:9:70,3/80389;90,22.74-44

    39-49.8,702070,3,/:3.9;0907,539-49.8,702070,3,/:3.9;0907,5

    489/010380

    7,3,0

    39-49.8

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    39-49.907,537,$:70739-49.907,537,$:707

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    39-49.839-49.8

    7,3.8:-89,3.08574/:.0/-2.747,3.8:-89,3.08574/:.0/-2.7447,382847,3828

    -994/08974473-974941-,.907,,3/-994/08974473-974941-,.907,,3/49072.7449072.7447,382847,3828

    $3909.47802$3909.4780283909.83909.

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    3/.,9434739-49.83/.,9434739-49.8

    $0;0794190310.943$0;0794190310.943 .:90.:90

    11:808033;4;081,8.,85,.0811:808033;4;081,8.,85,.08

    743.743.

    /06:,.417024;39084:7.041310.943/06:,.417024;39084:7.041310.943 03/7,3,0.,39-0089,-80/220/,9003/7,3,0.,39-0089,-80/220/,90

    %089,90415,90398489/010380%089,90415,90398489/010380 0-700-70

    42574280/489/010380842574280/489/0103808

    !745,8!745,8

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    $00.9434139-49.8$00.9434139-49.8

    090723000/090723000/

    %07,50:9.47!745,.9.:80%07,50:9.47!745,.9.:80

    %5041310.943%5041310.943 .:90743..:90743.$:8.059-9412.7447,382$:8.059-9412.7447,382

    090723022:3089,9:841905,9039090723022:3089,9:841905,9039

    448090,774089850.97:2,3/408994.9448090,774089850.97:2,3/408994.9

    0,,704190$/00110.98,3//0;04520394170889,3.00,,704190$/00110.98,3//0;04520394170889,3.0

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    $00.9434139-49.8$00.9434139-49.8

    &80257.907,574:930&80257.907,574:930 4770,90942489047,38284770,90942489047,3828

    39-49.39-49. ,.9074./,,.907489,9.,.9074./,,.907489,9.

    &80-,.907./,,39-49.815488-0&80-,.907./,,39-49.815488-0

    !70;4:8,/;078070,.9438!70;4:8,/;078070,.9438

    4.:80/907,54.:80/907,5

    4770,9094.:9:70,3/8:8.059-990894770,9094.:9:70,3/8:8.059-99089

    48941907,548941907,5

    0,,704190.48941,39-49.80,,704190.48941,39-49.8

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    42243:80/39-49.837,$:70742243:80/39-49.837,$:707

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    !03.3!03.3

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    !03.3!03.3

    09,,.9,2,39-49.09,,.9,2,39-49.

    489.42243:80/347,8:707489.42243:80/347,8:707

    789.4.01474/439403.310.943789.4.01474/439403.310.943

    ,.907./,3907107089.0,839088,.907./,3907107089.0,839088

    .4..,3/74/8574.0908,3,074-08.4..,3/74/8574.0908,3,074-08

    ,/;078070,.943088.4224347,,/;078070,.943088.4224347,

    =50780389;9=50780389;9

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    !03.3!03.3

    !70.,:9434397,3/.,9438!70.,:9434397,3/.,9438

    34307083,5,.9.$4.34307083,5,.9.$4.

    907,/;07800;0398:5809,770,907,/;07800;0398:5809,770,

    7:3907,.9438110.94347,.4397,.059;087:3907,.9438110.94347,.4397,.059;08

    54909.,850,3503.3.4:/25,7900110.9;0308841-7954909.,850,3503.3.4:/25,7900110.9;0308841-79.43974583,82,507.039,0414203#080,7.078.,397:04:998.43974583,82,507.039,0414203#080,7.078.,397:04:998

    5488-9-:934,7089:/08,;0574;0/8:.,30110.95488-9-:934,7089:/08,;0574;0/8:.,30110.9

    !,9039895447703,1:3.943!,9039895447703,1:3.943

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    74:5841!03.374:5841!03.3

    ,9:7,,9:7,!03.3'!03.3'!!03.3'!03.3'!

    903/0/850.97:2903/0/850.97:225.324.325.324.3

    42-3042-30,.9,2,803-947,.9,2,803-947:20393:20393

    !03.3,80!03.3,8070889,3970889,394,.3.4,.34,.3.4,.3

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    ,9:7,!,9:7,!03.3803.38

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    ,9:7,!,9:7,!03.3803.38

    !03.3:80/5,703907,!03.3:80/5,703907,

    !034209503.3!03':80/47,!034209503.3!03':80/47,

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    ,9:7,!,9:7,!03.3803.38

    0.,38241.9433-9.0,8390880.,38241.9433-9.0,839088

    $50.97:241,.943,774850.97:2$50.97:241,.943,774850.97:2

    ,3,.9;0,,3897,2,3,.9;0,,3897,25489;0-,.907,5489;0-,.907,

    $9,54.4..$970594.4..$9,54.4..$970594.4..

    #0889,3.0-09,#0889,3.0-09,,.9,2,803.70,80897050,90/,.9,2,803.70,80897050,90/:80:80

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    ,9:7,!03.3,9:7,!03.3 7,4727,472

    WW !03.3'!03.3'890549,88:28,941!03.3'890549,88:28,941!03.3'

    WW %8.02.,2574;0/1472.42-308,./%8.02.,2574;0/1472.42-308,./

    89,-99220/,9084:-9,3/7,5/89,-99220/,9084:-9,3/7,5/

    ,-8475943,-8475943

    /:9480/:9480

    !03'2546:39430!03'2546:39430

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    903/0/$50.97:2!03.38903/0/$50.97:2!03.38

    24.324.3

    25.325.3

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    903/0/$50.97:2!03.38903/0/$50.97:2!03.38

    903/0/903/0/850.97:2850.97:2

    4/10/943.:/07,230,9;0,074-.74/84/10/943.:/07,230,9;0,074-.74/8

    ,.70889,3.094-09,,.70889,3.094-09,,.9,2,80,.9,2,80

    .9;0,,3897,2.9;0,,3897,25489;0-,.907,-:9,8484205489;0-,.907,-:9,848420

    7,27,230,9;0-,.907,030,9;0-,.907,044

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    903/0/$50.97:2!03.38903/0/$50.97:2!03.38

    09907,-847-0/09907,-847-0/

    4307,14307,11010

    24.324.3

    /:9480/:9480 254685254685

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    42-3042-30,.9,2,803-947,.9,2,803-947:20393:20393

    :20393.439,38,.42-3,94341,24.3,3/:20393.439,38,.42-3,94341,24.3,3/.,;:,3,90549,88:2.,;:,3,90549,88:2

    ,;:,3,90549,88:28,147241.,;:,3.,./9,9,;:,3,90549,88:28,147241.,;:,3.,./9,9198-,.907,9,984190370889,3994503.38198-,.907,9,984190370889,3994503.38

    09,09,,.9,2,8070889,3.0,3/$9,54;07,0,.9,2,8070889,3.0,3/$9,54;07,0

    /:9480/:9480

    2,24.392.,;:3.,./542,24.392.,;:3.,./54685685

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    !03.3,80#0889,39!03.3!03.3,80#0889,39!03.3 4,.3,3/4,.3,3/.4,.3.4,.3

    %080,70503.3,80%080,70503.3,8070889,39503.389,9,;0,70889,39503.389,9,;0,

    24703,774850.97:241,.9;99,3903,9:7,24703,774850.97:241,.9;99,3903,9:7,

    503.38503.38

    %07,392.74-,011.,.8,20//70.9,,389%07,392.74-,011.,.8,20//70.9,,389

    503.3,80503.3,80574/:.3897,38417,25489;0.4..574/:.3897,38417,25489;0.4..

    5,79.:,75,79.:,7$9,54.4..,$9,54.4..,850.08850.08

    &80/3$,;,7,3/310.9438&80/3$,;,7,3/310.9438

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    3/,2.33/,2.3

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    3/,2.33/,2.3

    98,950413.48,2/0,39-49.98,950413.48,2/0,39-49.

    .9;0,,38924897,25489;0,3/,3,074-..9;0,,38924897,25489;0,3/,3,074-.

    47,3828,3/$9,547,3828,3/$9,5

    44/-430503097,94344/-430503097,943

    &801:380;0704/439403.310.9438&801:380;0704/439403.310.9438

    3/,2.33-985749038390883/,2.33-98574903839088

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    3/,2.33/,2.3

    $/00110.983.:/058:0/4202-7,34:8.4982/$/00110.983.:/058:0/4202-7,34:8.4982/

    3,:80,,3//,770,0:4503,,3/05,9494.93,:80,,3//,770,0:4503,,3/05,9494.9

    5038;05038;0

    /:9480/:9480

    25462546 8585

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    09743/,4009743/,40

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    09743/,4009743/,40

    44/1477,20,9;0,3,074-.47,382844/1477,20,9;0,3,074-.47,3828

    0,-847-0/394,-8.088080,-847-0/394,-8.08808

    WW ,.907./,,.907./,

    %4970,98074:8310.9438.,:80/-,3,074-.-,.907,%4970,98074:8310.9438.,:80/-,3,074-.-,.907,.42-30/9.42-30/9,.9,2,.9,2

    110.9;0,,389,.9074/08850.0808535074/439,110.9;0,,389,.9074/08850.0808535074/439,310.9438310.9438

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    09743/,4009743/,40

    !70.,:943835,903989544705,9.1:3.943,!70.,:943835,903989544705,9.1:3.943,;4/3;4/3

    5703,3942035703,394203

    WW

    7:3907,.94388:17,2,.9439,.44,71,737:3907,.94388:17,2,.9439,.44,71,73&350,8,39209,.9,890&350,8,39209,.9,890

    42243:80/09743/,4042243:80/09743/,40 ,,

    /:9480/:9480

    26542654/,8/,8

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    05,48547305,485473

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    05,48547305,485473

    47070889,3.094503.3,8047070889,3.094503.3,80

    .4..2,3.4..2,374/874/8

    %7/0307,943!80:/4243,8%7/0307,943!80:/4243,8,07:348,,07:348,

    $0.43/.4.00880110.9147,3,074-08$0.43/.4.00880110.9147,3,074-08

    7890307,9437890307,943 $0.43/0307,943$0.43/0307,943 %7/0307,943%7/0307,943 4790307,9434790307,943

    01,4301,43

    &&$'$'

    %/30%/30

    01470147

    &.01,2&.01,2

    ,147,3,147,3 010520010520

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    ,.74/0,.74/0 39-49.839-49.8

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    ,.74/0,39-49.,.74/0,39-49.

    79742.39742.3,3/,79742.379742.39742.3,3/,79742.3

    ,3-,.907489,9.,3-,.907489,9.

    $50.97:282,794!03'$50.97:282,794!03'

    0880110.9;0,,38947,,3,074-080880110.9;0,,38947,,3,074-08

    .4..47,,3,074-08.4..47,,3,074-08

    79742.379742.3

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    79742.379742.3

    3-985749038390883-98574903839088

    $/00110.983.:/03,:80,;4293/,770,,3/$/00110.983.:/03,:80,;4293/,770,,3/

    05,99805,998

    /:9480/:9480

    ,80890,7,900894,90,80890,7,900894,90

    25462546 /,8/,8

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    39-49.839-49.8 !4398%4#0202-07!4398%4#0202-07

    &809079/7:&809079/7:

    &809079/480&809079/480

    &8090.4770.9/4838.0/:0&8090.4770.9/4838.0/:0

    4770.9/:7,9434770.9/:7,943

    &80,4,/3/480947,5/,.0;0907,50:9.-44/0;08&80,4,/3/480947,5/,.0;0907,50:9.-44/0;08

    ;4/.42-3,943841-,.907489,9.,3/-,.9074./,/7:8;4/.42-3,943841-,.907489,9.,3/-,.9074./,/7:8

    438/07190310.94385708039/,8471342574;02039438/07190310.94385708039/,8471342574;02039

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    39-49.!745,837,$:70739-49.!745,837,$:707

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    39-49.!745,894570;039-,.907,03/4.,7/9839-49.!745,894570;039-,.907,03/4.,7/98

    3/.,94383/.,9438 %0207.,30,79884.,943:/0308,70,20/,95,9039844:/,;09070,9089%0207.,30,79884.,943:/0308,70,20/,95,9039844:/,;09070,9089

    /,30741,-,/4:9.420190/0;0450/,0,79310.943/,30741,-,/4:9.420190/0;0450/,0,79310.943

    791.,0,79;,;08791.,0,79;,;08

    894741310.9;003/4.,7/98894741310.9;003/4.,7/98

    079,3850.1.8074:8.43039,0,79.43/94383.:/3079,3850.1.8074:8.43039,0,79.43/94383.:/3

    :3705,70/473.425090705,70/.,349..43039,0,79/80,803.:/3948095,,9;0:3705,70/473.425090705,70/.,349..43039,0,79/80,803.:/3948095,,9;0

    8:398,3/.43/:988:398,3/.43/:98

    ,.425090705,70/.43039,0,79/010.995748909.2,907,47/0;.009075,.0/-,.425090705,70/.43039,0,79/010.995748909.2,907,47/0;.009075,.0/-

    8:70747-.,909073907;03943/:73901789824398,190790574.0/:708:70747-.,909073907;03943/:73901789824398,190790574.0/:70

    ,3705,70/.43039,0,79/010.99708/:,/010.9,99089047,/,.039949089041,,3705,70/.43039,0,79/010.99708/:,/010.9,99089047,/,.039949089041,

    5748909.5,9.47,5748909./0;.05748909.5,9.47,5748909./0;.0

    .,7/,.97,385,399,9/0;0458,574-023,0,79;,;0.,7/,.97,385,399,9/0;0458,574-023,0,79;,;0

    &5/,90/57

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    39-49.!745,839-49.!745,8

    %0:/03083/.,909,990144374:541%0:/03083/.,909,990144374:541

    5,90398344307300/,35745,.9.,39-49.894570;0395,90398344307300/,35745,.9.,39-49.894570;039-,.907,03/4.,7/98-,.907,03/4.,7/98

    97,;,;0574,58097,;,;0574,580

    #0:2,9.0,79/80,80#0:2,9.0,79/80,80

    .:85/;,;0/80,80.:85/;,;0/80,80

    ,.10/,479.8903488,.10/,479.8903488

    43039,0,79.43/94388:.,8;0397.:,78059,43039,0,79.43/94388:.,8;0397.:,78059,/010.9'$,97,8059,/010.9$,3/5079745./010.9'$,97,8059,/010.9$,3/5079745..,7/4245,9.,7/4245,9

    &5/,90/57

  • 8/3/2019 Antibiotics OMS

    48/53

    39-49.!745,839-49.!745,8 475,903989439475,903989439705,.02039705,.02039

    %0$207.,3.,/024179450/.$:70438%0$207.,3.,/024179450/.$:70438

    89,90203970.42203/8,39-49.5745,81475,90398489,90203970.42203/8,39-49.5745,81475,903984

    ,;0:3/07430949,439705,.02039-01470,33;,8;0,;0:3/07430949,439705,.02039-01470,33;,8;0

    574.0/:709,92,574/:.0-,.90702,70,7/0884190039574.0/:709,92,574/:.0-,.90702,70,7/088419003941920,190790439705,.020398:70741920,190790439705,.020398:707

    39-49.5745,8839-49.5745,88%% 70.42203/0/147/039,5,9039870.42203/0/147/039,5,90398

    95,908538478.70895,908538478.708

    $ 0-7:,7

  • 8/3/2019 Antibiotics OMS

    49/53

    39-49.5745,839-49.5745,8 90743/943890743/9438

    97,.943847-438:7075,330/3570;4:87,/,94397,.943847-438:7075,330/3570;4:87,/,943

    10/10/

    ,3.07.024907,5,3.07.024907,5

    &3.439740/475447.439740//,-0908&3.439740/475447.439740//,-0908

    22:3422:34.42574280/5,90398070908.42574280/5,90398070908

    .082222470884790-84:90.082222470884790-84:90

    0:97454:398.082222470880:97454:398.08222247088

  • 8/3/2019 Antibiotics OMS

    50/53

    39-49.5745,839-49.5745,8 90743/943890743/9438

    3/03;,8.:,7.,909078:.,8!4793/03;,8.:,7.,909078:.,8!479,,.,98.,98

    #03,1,:709024/,88,3/,79074;034:88:39,55,3.0#03,1,:709024/,88,3/,79074;034:88:39,55,3.0

    $$

    44//8.7,8,844//8.7,8,8

    $8902.:5:807902,948:8$8902.:5:807902,948:8

    %7,385,3970.503983.:/347,397,385,398-4302,774%7,385,3970.503983.:/347,397,385,398-4302,774

    97,385,398,3/8902.097,385,39897,385,398,3/8902.097,385,398

  • 8/3/2019 Antibiotics OMS

    51/53

    39-49.!745,8 #0203

  • 8/3/2019 Antibiotics OMS

    52/53

    42243#0,843814739-49.,:7042243#0,843814739-49.,:70

    30.70,837/0741!74-,-025479,3.030.70,837/0741!74-,-025479,3.0

    ,:70948:7.,07,/.,909084:7.04190310.943,:70948:7.,07,/.,909084:7.04190310.943

    %444,-44/,39-49..43.0397,943%444,-44/,39-49..43.0397,943

    3,-94190,39-49.94503097,909490890413,-94190,39-49.94503097,90949089041310.943310.943

    25,70/3,/06:,90489/010380825,70/3,/06:,90489/0103808

    !,90391,:70949,090,39-49.!,90391,:70949,090,39-49.

    3,557457,90.4.041,39-49.3,557457,90.4.041,39-49.

    290/;,8.:,7947-44/14290/;,8.:,7947-44/14

    20703.041,39-49.70889,3.020703.041,39-49.70889,3.0

    0,3/,34880,3/,3488

    3.4770.9/,34883.4770.9/,3488

  • 8/3/2019 Antibiotics OMS

    53/53

    39-49.8347,8:70739-49.8347,8:707 $:22,7$:22,7

    0.84341090794;0,39-49.88-,80/43900.84341090794;0,39-49.88-,80/4390

    3/;/:,.,803/;/:,.,80

    9825479,3994.438/079022:3089,9:841905,90399825479,3994.438/079022:3089,9:841905,9039

    0,989,9:889,9041310.943.:90743.09039410,989,9:889,9041310.943.:90743.0903941

    8:7078/00110.98/0;04520394170889,3.0,3/.4898:7078/00110.98/0;04520394170889,3.0,3/.489

    -014705708.7-3,3,39-49.-014705708.7-3,3,39-49.