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ANTIMICROBIAL TECHNOLOGY

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Page 1: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

ANTIMICROBIAL

TECHNOLOGY

Page 2: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Antimicrobial technology

Non-migrating & durable technology with a

broad spectrum of activity against microbes

No migration to the skin nor to the environment

Quick and easy to verify

Outstanding safety and registration profile

Page 3: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Home textiles

Excrements

Dust & allergens

Drying out

Human being

micro fungi

A. repens

Skin scales

Dust

mite

Warmth &

humidity

Dust mites

Page 4: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Benefits of the BI-OME technology

Long-lasting freshness

Eliminates the smells created by yeast,

fungus and bacteria in the product

Controls or eliminates microbial

staining of the treated article

Page 5: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Antimicrobial agents - Mode of action

Conventional organic and inorganic active substances

Migration

from substrate to bacteria

for antimicrobial action

No migration

mechanical process

for antimicrobial action

Unconventional organo functional silane active substances

Page 6: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Diffuse from the substrate to the microbe:

• Leach or migrate out of the substrate into the

environment

• Are consumed by micro-organisms

• Chemically interrupt (poison) the cell

• May cause adaptive micro-organisms

• Leach out in contact with water or humid

conditions

Migrating antimicrobials

Page 7: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Migrating antimicrobials

Zone of inhibition in agar diffusion tests

Page 8: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Are bounded to the substrate and require a contact by the microbe:

Are bonded to the product surface

Are not consumed by micro-organisms

Mechanically interrupts (stabs) the cell wall

Remain functional for the life of the product

Will not cause adaptive micro-organisms

Non migrating antimicrobials

Page 9: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Organo functional silanes

N-halamines

Grafting by irradiation

Non migrating antimicrobials

Antimicrobial active substances that do not migrate in order

to be active are for example:

No zone of inhibition => no sub lethal concentration => no adaptation

Page 10: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

The BI-OME technology: disruption

Cell disruption mechanism

Disruption

Each micro-organism will come into contact

with approximately 25.000 “swords” at the

surface.

Page 11: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Microbiology lab

Page 12: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

International tests

Regions Micro OrganismsAgar

DiffusionParallel Streak Shake Flask Count Test

Mould & Mildew

Resistance

Soil Burial /

Rot proof

Saturated

atmosphere

Bacteria SN 195 920

Fungi SN 195 921EMPA 223-10

ASTM G 21-96

EMPA 223-11

EN ISO 11721-1BS 6508 Part V

Bacteria AATCC 147Shake Flask

ASTM E 21-49AATCC 100

FungiAATCC 30

Part III

AATCC 30

Part I

AATCC 30 Part

IV

BacteriaJIS L 1902

qualitative

Shake Flask

SEK

JIS L 1902

quantitative

Fungi

General

Overview of the most important antimicrobial tests world wide

SANITIZED Standard Tests are effected according to the Swiss Norm (SN 195 920 and SN 195 921). Other tests have to be agreed upon.

Japan

USA

Page 13: ANTIMICROBIAL TECHNOLOGY - Sanapur · AATCC 100 Fungi AATCC 30 Part III AATCC 30 Part I AATCC 30 Part IV Bacteria JIS L 1902 qualitative Shake Flask SEK JIS L 1902 quantitative Fungi

Test certificate