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Dr. Daniel Kalish

Anxiety, Depression, Weight Gain, Fatigue: Applying Organic Acids Testing

in Your Practice

Kalish Ins*tute © 2016 by Dr. Daniel Kalish. All rights reserved.

INTRODUCTION

•  24 years of patient experience, with over thousands of patients world wide

•  Trained over 1,000 practitioners in The Kalish Method of functional medicine

•  Conducted a research study with Mayo Clinic researchers on The Kalish Method


LEARNING OBJECTIVES

•  Learn when and how to effectively use organic acid testing in your practice

•  Learn how to assess the origins of fatigue, weight gain and depression in your patients based on organic acids testing

•  Be able to successfully communicate the value of organic acid testing to your patients so they can comprehend its contribution to their healing process


KALISH METHOD 101 – Regular Price $397This 8 hour online lecture series:•  Functional Medicine Philosophy•  Stress Hormones•  Leaky Gut and the Microbiome•  Toxins and Detoxification•  Brain Imbalances•  The 5 Pillars of Building a Successful Practice•  Live call with Dr. Kalish to answer your specific questions What else is included?•  Downloadable Resources – powerpoints, audio files and

transcriptions of all lectures, Patient Program Guide and 2 eBooks

Special Price of $199 with Promo Code: FMTown50


KALISH METHOD TREATMENT MODEL

UNDERLYING CAUSE

BODY SYSTEMS

PHYSIOLOGICAL DAMAGE

SYMPTOMS


KALISH METHOD TREATMENT MODELUnderlying Cause Physiological Damage Body Systems Symptoms

Emotional/spiritual (trauma/abuse/chronic stress/addiction)

Dietary (blood sugar, poor diet, nutrient deficiencies, dairy, food allergies)

Gluten

GI infections

Toxins (heavy metals, chemicals)

Genetics/Epigenetics

Structural (physical trauma, chronic injury, pain, posture)

Sleep

Exercise

Medications/surgery

Dental

Lyme, mold, viral or bacterial (SIBO, environmental exposure)

Inflammation

Catabolic Physiology

Insulin Resistance

Oxidative Stress

Neuroendocrine

GI

Liver

Weight gain

Fatigue

Depression

Anxiety

GI problems (gas, bloating, constipation, diarrhea, heartburn)

Sex hormone imbalance (low sex drive, infertility, hot flashes, nightsweats, PMS, PCOS)

Pain

Allergies

ADHD

Insomnia

Brain fog

Sugar cravings

Skin problems

AutoimmuneKalish Ins*tute © 2016 by Dr. Daniel Kalish. All rights reserved.

DOCTOR-‐ PATIENT EQUILIBRIUM

UNDERLYING CAUSE

PHYSIOLOGICAL DAMAGE

BODY SYSTEMS SYMPTOMS


GISYSTEM

THE TREATMENT MAP


GI

DETOX

NEUROENDOCRINE

STANDARD TREATMENT SEQUENCE


PROGRAM DESIGN

New pa*ent intake

• Pains • Gains • Life Goals

Lifestyle tasks

• Food • Exercise • Sleep • Medita*on/stress reduc*on

Supplement programs

• Therapeu*c programs • Long term maintenance

PROGRAM DESIGN

FACTORS


WAYS THE OAT CAN BE INTERPRETED

Organic Acids Markers

The 4 Horsemen The 3 Body Systems

Common Patient PresentationsKalish Ins*tute © 2016 by Dr. Daniel Kalish. All rights reserved.

FOUR HORSEMEN OF PHYSIOLOGICAL DAMAGE

INFLAMMATION

INSULIN RESISTANCE

CATABOLIC PHYSIOLOGY

OXIDATIVE STRESS


THE 3 BODY SYSTEMS


GI SYSTEM

DETOX SYSTEM

NEUROENDOCRINE SYSTEM

SEVEN SECTIONS OF OAT BY BODY SYSTEM

(1) Carbohydrate Metabolism(2) Energy Production (3) Neurotransmitter Metabolism

(4) Bacterial, Clostridial, and Yeast

(5) Detoxification (6) Oxidation(7) Methylation


ORGANIC ACIDS TESTING- GI SYSTEM

(4) GI •  Bacteria•  HCL•  Yeast overgrowth•  Clostridial markers

GI SYSTEM

The Road to Immunity: Kenneth Bock, M.D.

Deregulating factors•  Medications•  Alcohol•  Food allergies•  Infectious agents•  Pollutants•  Stress•  Low stomach acid•  Low secretory IgA

GI tract is overburdened;

imbalances result

Poorer absorption of nutrients

Higher levels of toxins & allergens are absorbed through gut mucosa.Creates food

allergies

Liver is overburdened

Fewer nutrients are available for defense

and repair

Bioaccumulation of toxins that are not

excreted

More detoxifying creates increased

oxidant stress

•  Metabolic poison•  Chronic illness•  Alterations in organ function

•  Immune suppression•  Cellular damage

•  Free radical damage•  Mitochondrial problems

Additional burdens Toxic chemicals Hormones Antigen/antibody complexes

GI INFLAMMATION / STRESS CONNECTION

•  Glutamine- drops due to gluconeogenesis, easily lost under stress•  Gluconeogenesis finds gut lining easy to draw from, which leads to

leaky gut from abnormal diet, bacterial endotoxins and mucosal atrophy

•  Dysfunction of gut can lead to systemic inflammation BUT inflammation in other parts of body can impact the gut too

•  Cholesterol increases to combat the increase in free radicals due to the abundance of inflammation

PATIENTS WITHOUT GI COMPLAINTS CAN STILL HAVE GI ISSUES

YEAST AND CLOSTRIDIAL MARKERS: D-ARABINITOL

High D-Arabinitol: Yeast overgrowth. Yeast feeds on anything that breaks down into sugar /glucose.

Can be caused by: •  Protein malabsorption•  Antibiotic use•  Stress•  Oral contraception

Symptoms: Yeast overgrowth can interfere with absorption, causing leaky gut. It gives off tremendous amounts of toxins causes bloating, gas, constipation and diarrhea. Drives sugar cravings.

•  High sugar/processed food intake•  Parasites•  Food sensitivities

YEAST OVERGROWTH MAY MEAN THAT YOU NEED TO LOOK DEEPER

Yeast overgrowth often secondary to other infections

In over 90% of giardia cases, yeast is present

Most patients found positive on PCR for Candida positive for gluten intolerance

DETOX SYSTEM

ORGANIC ACIDS TESTING- DETOX SYSTEM

(5) Detoxification •  Phase 2 Detoxification Pathways

(6) Oxidation•  Antioxidant Protection

(7) Methylation•  B12•  Folate

DETOX SYSTEM

CATEGORIES OF TOXINS

INDUSTRIAL CHEMICALS

HERBICIDES

ENVIRONMENTAL TOXINS

GMO FOODS

BIOTOXINS PESTICIDES

HEAVY METALS

SOLVENTS

BODY BURDEN

The accumulation of toxic chemicals in the body, both naturally occurring and man-made

Chemicals can be inhaled, swallowed, or absorbed through the skin

When investigating body burden, you can include the total amount of chemicals, or the burden of a single chemical

May be represented by breakdown products of chemicals that are stored within the body’s compartments and tissues

U.S. Environmental Protection Agency paper from 1987 estimated that everyone alive carries within their body at least 700 contaminants, most of which have not been studied at all

BODY TOXICITY

•  Many toxins that we confront are lipophilic toxins, and they are made by their manufacturers specifically to be lipophilic

•  Lipophilic toxins love fatty tissue and will seek the fatty tissue in the body to attach themselves to

•  Largest collection of fatty tissue in the body is the brain - after that, all other fat stores are known repositories for lipophilic substances

THE PROBLEM

Lipids (from fatty acids) comprise 60 to 80% of the central nervous system

Deficiency makes the nervous system vulnerable to fat-soluble toxins such as mercury and pesticides

Without enough fluid intake, the kidneys become contaminated with toxic metals, injuring the membranes and interfering with proper filtration of toxins

Proper hydration and balanced electrolyte solutions are important

RATIONALE FOR DETOXIFICATION

LIVER DETOX PATHWAYS

Phase One: B vitamins, glutathione, antioxidants, vitamin C, vitamin E

Phase Two: glycine, taurine, glutamine, cysteine

DETOXIFICATION

TOXINS CAUSE WEIGHT GAIN AND FATIGUE TOXINS PREVENT FAT BURNING AND

DAMAGE MITOCHONDRIA

Deficiencies or elevations in these markers indicates abnormalities in Phase 1 & Phase 2 detoxification

Arginine NAC Methionine

Glycine Mg Antioxidants

Organic acids detox markers :

DETOXIFICATION MARKERS

OXIDATION

OXIDATIVE STRESS

•  Free radicals cause severe damage to the normal cells of the body, which can manifest into diseases such as heart disease and cancer

•  DNA damage is induced by oxidative stress•  Inflammation and free radical activity go hand in hand•  Excessive oxidative stress can cause liver damage •  Oxidation markers don’t tell you where the oxidation is coming from,

but more how is the person handling the oxidative stress

WHO DO WE USE ORGANIC ACIDS TESTING WITH?

EVERYONE…•  Complex patients •  Simple patients •  Annual health assessment for long term maintenance •  Prenatal nutritional programs•  Chemotherapy and radiation recovery programs•  Weight loss•  Fatigue•  Depression/anxiety•  GI factors especially when stool testing normal


COMMON PATIENT PRESENTATIONS

Overweight/ tired patient

Digestive issues patient

Brain issues patient

Catabolic patient

Toxic patient


CHRONICALLY ILL PATIENTS

•  The more complicated a patient is, the more the basics become essential

•  Most chronically ill patients have major metabolic imbalances•  May not be respond to treatment because the underlying

metabolic issues are still present, even though the proximate immediate issue has been resolved

•  Can extrapolate from critical care literature to our patient base•  Leaky gut is almost always present in chronically ill patients


SUMMARY

KEY CONCEPTS:•  Complex but highly effective tool that allows a practitioner to

see a variety of patient’s body processes in depth•  Organize programs by body system utilizing the 7 sections

of the Organic Acids Test to group markers together•  View the results in several ways using the 4 Horsemen, 3

body systems, by individual organic acids markers, and patient archetype

•  Invaluable tool in creating an individualized supplementation program


KALISH METHOD 101 – Regular Price $397This 8 hour online lecture series:•  Functional Medicine Philosophy•  Stress Hormones•  Leaky Gut and the Microbiome•  Toxins and Detoxification•  Brain Imbalances•  The 5 Pillars of Building a Successful Practice•  Live call with Dr. Kalish to answer your specific questions What else is included?•  Downloadable Resources – powerpoints, audio files and

transcriptions of all lectures, Patient Program Guide and 2 eBooks

Special Price of $199 with Promo Code: FMTown50


anxiety, depression, weight gain, fatigue: applying ...fmtrainingcenter.s3.amazonaws.com/guest...

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