appendix 1: systematic review summary form › files › 9714 › 9483 … · web viewappendix 1:...

Appendix 1: Systematic Review Summary FormGuideline Title: Guidelines for the management of nausea and vomiting in palliative care

Systematic Review Summary Form - AprepitantReviewers: Sian Rae (Pharmacist) Tania Forrester (Palliative Care CNS)

Aprepitant

Records identified through database

searching (n = )

Records identified through Embase

database searching (n = 211 )

Selection of databases and search terms (e.g. Web of Knowledge, SCOPUS, MEDLINE, PsycINFO, CINAHL, Cochrane)

Studies included in final literature review

(n = 7 )

Full-text articles excluded, with reasons (n = 3 )

Full-text articles assessed for eligibility (n = 10 )

Records excluded (n = 250 )Records screened

(n = 260 )

Records after duplicates removed (n = 260 )

Additional records identified through

other sources (n = )

IDENTIFICATION

ELIGIBILITY

INCLUDED

SCREENING

Records identified through Medline

database searching

(n = 227 )

Systematic Review Summary Form - CyclizineReviewers: Sian Rae (Pharmacist) Tania Forrester (Palliative Care CNS)

Cyclizine

Records identified through database

searching (n = )

Records identified through Embase

database searching (n = 76 )

Selection of databases and search terms (e.g. Web of Knowledge, SCOPUS, MEDLINE, PsycINFO, CINAHL, Cochrane)


(n = 1 )

Full-text articles excluded, with reasons (n = 3 )

Full-text articles assessed for eligibility

(n = 4 )

Records excluded (n = 47 )Records screened

(n = 51 )

Records after duplicates removed (n = 51 )

Additional records identified through

other sources (n = )

IDENTIFICATION

ELIGIBILITY

INCLUDED

SCREENING

Records identified through Medline

database searching

(n = 21 )

Systematic Review Summary Form - DexamethasoneReviewers: Ann Griffiths (Macmillan Palliative Care CNS) Agnes Noble (Palliative Care CNS)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y

I D E N TI FI C A TI O N


(n = 0)


(n =0 )

What is the evidence for the use of Dexamethasone in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - DomperidoneReviewers: Ann Griffiths (Macmillan Palliative Care CNS) Agnes Noble (Palliative Care CNS)

Records identified

(n =838 )

Records excluded (n = )

Chemotherapy = 108Not relevant = 153

Not Dexamethasone = 1Children = 27

Post operative = 45Case Reports/Review Articles =

26Unable to access full article = 1

Full-text articles excluded, with reasons (n =14 )

Dexamethasone not main focus = 7

Not treatment related = 1Not nausea/Vomiting = 3Randomized control = 2

Case Report = 1

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y



(n = 0)


(n =0 )

What is the evidence for the use of Domperidone in the management of nausea and vomiting in palliative care?

Records screened (n = 97)

Search criteria and search terms used Nausea” OR “Vomiting” AND “Dexamethasone” NOT “chemotherapy”

Systematic Review Summary Form - GranisetronReviewers: Dr Séamus Coyle, Dr James Barfield

Records identified

(n =329 )


Records excluded (n = 97)

+ reasons why excludedPost Operative N+V = 3

Chemotherapy related N+V = 2Children = 7

Does not meet search criteria =51 Review/Case Report = 34

Full-text articles excluded, with reasons

(n = )

Search criteria and search terms used Nausea” OR “Vomiting” AND “Domperidone” NOT “chemotherapy”

Records identified

(n = 51)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y




n= 32 treatment relatedn=4 wrong medicationn=4 different symptom

n=3 unrelated


(n = 8)


(n = 0)


(n = 8)

Search criteria and search terms used Nausea” OR “Vomiting” AND “Granisetron” NOT “chemotherapy”

What is the evidence for the use of Granisetron in the management of nausea and vomiting in palliative care?

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y


Systematic Review Summary Form - Haloperidol

Reviewers: Ann Griffiths (Macmillan Palliative Care CNS) Agnes Noble (Palliative Care CNS)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y



(n = 12)


(n = 4)

MEDLINEWhat is the evidence for the use of Haloperidol in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - Hyoscine ButylbromideReviewers: Ann Griffiths (Macmillan Palliative Care CNS) Agnes Noble (Palliative Care CNS)

Records identified

(n =12 )

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y


Records screened (n =3 )


Not relevant = 3


(n = 0) Full-text articles excluded, with reasons

(n = )


(n = 0)

Search criteria and search terms used Nausea” OR “Vomiting” AND “Hyoscine Butylbromide” NOT “chemotherapy”

What is the evidence for the use of “Hyoscine Butylbromide” in the management of nausea and vomiting in palliative care?

Records identified

(n = 269 )

Records screened (n =88 )

Records excluded (n =84)

Duplicates = 1Chemotherapy = 18Not relevant = 36

Review = 15Case Report = 11

Post-Operative = 3


(n =8)Not specific to search

criteria

Search criteria and search terms used “nausea” OR “vomiting” AND “Haloperidol” Filters: Humans, English, Adults, Evidence

base, Clinical Trials

Systematic Review Summary Form - Hyoscine Hydrobromide

Reviewers: Dr Laura McGlynn, Dr Richard Latten

Records identified (n = 15 )

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y


Records screened (n = 15 )

Records excluded (n = 15 )

Irrelevant to search – 10Duplicates - 5


(n = 15 ) Full-text articles excluded, with reasons

(n = 15)


(n = 0 )

Nausea” OR “Vomiting” AND “Hyoscine Hydrobromide” NOT “chemotherapy”

What is the evidence for the use of Hyoscine Hydrobromide in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - Levomepromazine

Reviewers: Dr Séamus Coyle, Dr James Barfield

Records identified

(n = 10)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y




n=1 not englishn=2 reviews

n=1 chemotherapy relatedn=4 other symptoms


(n = 2)Full-text articles excluded

n = 1 (a case report)


(n = 1)

Search criteria and search terms used Nausea” OR “Vomiting” AND “Levomepromazine” NOT “chemotherapy”

What is the evidence for the use of Levomepromazine in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - Lorazepam

Reviewers: Dr Paula Powell, Tracy Hindley (RN)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y




(n = 1)


(n = 0)

Systematic Review Summary Form - MetoclopramideReviewers: Dr Laura McGlynn and Dr Richard Latten

Records identified (n = 450)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y


Records screened (n = 450 )


Not Metoclopramide = 4Post Operative N+V = 19Chemotherapy related N+V = 176Children = 24Does not meet search criteria = 175Unable to access full article = 28


(n = 24 )


(n = 15)Not specific to search

criteria


(n = 9 )

MEDLINE Search Nausea” OR “Vomiting” AND “Metoclopramide” NOT “chemotherapy” “Clinical Trials” “Evidence base” “Cochrane” “Humans” “Evidence based medicine”

What is the evidence for the use of Metoclopramide in the management of nausea and vomiting in palliative care?

Records identified

(n = 91)



n = 1 multimodal treatment

Search criteria and search terms used Nausea” OR “Vomiting” AND “Lorazepam” NOT “chemotherapy”

What is the evidence for the use of Lorazepam in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - Olanzapine

Reviewers: Dr Paula Powell, Tracy Hindley

Records identified

(n = 36)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y





(n = 6)Full-text articles excluded,

with reasons (n = 3)


(n = 3)

Search criteria and search terms used Nausea” OR “Vomiting” AND “Olanzapine” NOT “chemotherapy”

What is the evidence for the use of Olanzapine in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - Ondansetron

Reviewers: Dr Laura McGlynn and Dr Richard Latten

Records identified

(n = 232 )

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y




Duplicates = 2Chemotherapy = 205

Not relevant = 12Not Ondansetron = 2

Children = 10Post operative = 1


(n = 0 )Full-text articles excluded,

with reasons (n = 0 )


(n = 0)

Search criteria and search terms used “nausea” OR “vomiting” AND “Ondansetron” Filters: Humans, English, Adults, Evidence

base, Clinical Trials

MEDLINEWhat is the evidence for the use of Ondansetron in the management of nausea and vomiting in palliative care?

Systematic Review Summary Form - Prochlorperazine

Reviewers: Dr Paula Powell, Tracy Hindley (RN)

Records identified

(n = 135)

S C R E E N I N G

I N C L U D E D

E LI G IB IL IT Y





(n = 16)Full-text articles excluded,

with reasons (n = 11)

n=2 unable to obtain


(n = 3)

Search criteria and search terms used Nausea” OR “Vomiting” AND “Prochlorperazine” NOT “chemotherapy”

What is the evidence for the use of Prochlorperazine in the management of nausea and vomiting in palliative care?

appendix 1: systematic review summary form › files › 9714 › 9483 … · web viewappendix 1:...

Documents