applications and indications of medical ozone.pdf

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    May 23, 2003 OZONOSAN 1

    OzoneOzone--TherapyTherapyApplicationsandIndications

    of

    Medical Ozone

    Ozone Seminar Bad Kreuznach

    March 26 27, 2004

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    May 23, 2003 OZONOSAN 2

    MedicalMedical OzoneOzoneMedical Ozone is a mixture of pureOxygen and pure Ozone

    0,05 % O 3 - 5 % O3 (Vol.)

    99,95 % O2 - 95 % O2

    1 g /ml - 100 g/ml O3

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    May 23, 2003 OZONOSAN 3

    ProcessingProcessing ofof thethe

    MedicalMedical

    OzonegeneratorOzonegenerator::

    OZONOSANOZONOSAN

    Ozone-

    production

    Catalyst:

    O3 O2

    Photometric

    ozonemeasurement

    Ozone

    supplyer

    Ozoneapplications

    Ozonesuction

    pump

    Catalyst:

    O3 O2

    O2 O3 O3

    O3

    O3

    O3O3O2

    O2

    O2

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    May 23, 2003 OZONOSAN 4

    OZONOSANOZONOSAN

    photonikphotonik

    equiped withequiped with UVUV--PhotometerPhotometer

    forforcontinous measurementcontinous measurement

    ofof ozone concentrationsozone concentrations

    ConcentrationConcentration rangerange::

    11-- caca 80 g/ ml80 g/ ml

    SuctionSuction pumppump

    highlyhighly effectiveeffective catalyzercatalyzersystemsystemOption:Option: unit for ozononized waterunit for ozononized water

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    May 23, 2003 OZONOSAN 5

    OZONOSANOZONOSAN

    alphaalpha plusplus

    equiped withequiped with UVUV--PhotometerPhotometer

    for continous measurementfor continous measurement ofof

    OzoneOzone concentrationsconcentrations

    Concentration rangeConcentration range::

    11-- ca130 g/ mlca130 g/ ml

    SuctionSuction pumppump

    highly effective catalyzerhighly effective catalyzersystemsystemIntegrated unit forIntegrated unit forozonized waterozonized water

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    May 23, 2003 OZONOSAN 6

    IndicationsIndications ofof OzonetherapyOzonetherapy

    lExternal Ulcers and Skin Lesions

    lArterial Circulatory Disorders

    lImmunodeficiency and Immunodysbalance

    - Additive Therapy in Carcinoma Patients

    - Virus Caused Diseases

    lRheumatic Diseases

    lInflammatory Conditions

    lDentistry

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    May 23, 2003 OZONOSAN 7

    Systemic FormsSystemic Forms ofofApplicationApplication

    lMajor Autohemotherapy MAH asextracorporeal blood treatment with O3 andreinfusion of activated blood

    lRectal Insufflation of O3-O2 mixture

    lMinor Autohemotherapy as intramuscularinjection of activated blood

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    May 23, 2003 OZONOSAN 8

    MajorMajorAutohemotherapyAutohemotherapy

    Major Autohaemotherapy

    as extracorporeal blood

    treatment avoiding intra-

    vascular gas applicationforms.

    Indications:

    - Arterial circulatorydisorders

    - Immunomodulation- Rheumatoid arthritis

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    May 23, 2003 OZONOSAN 9

    Rectal insufflationRectal insufflation

    forforsystemicsystemic undund topicaltopical efficacyefficacy

    1. Dosing ball (150 ml)

    2. Ozone reserve container

    3. Lock valve

    4. Return valves

    5. Connection tube (luer)

    6. Catheter

    Indications:

    Proctitis

    Colitis and the

    Indications for Major

    Autohemotherapy

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    May 23, 2003 OZONOSAN 10

    UlcerousUlcerous

    ProctocolitisProctocolitisFlorid Stage of Proctocolitis:

    Pat. female, 45 yrs. Destruction

    of epithelium, cryptal abscesses,

    massive leucocytic infiltration,

    partially under inclusion of the

    tunica propria (350x)

    Control biopsy after 4 weeks:

    Manifest reversal of

    inflammation. Intact epithelium

    after rectal ozone insufflation

    with 20-30 g/ml and 300 to 500

    ml in volume.

    (Knoch et al. Aktuelle Koloproktologie)

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    May 23, 2003 OZONOSAN 11

    UlcerousUlcerous

    ProctocolitisProctocolitis

    Florid Stage of ColitisPat. male 62 yrs. Cryptitis withcryptal abscesses, chronic

    inflammation, destruction of the

    epithelium and massive infiltration of

    leucocytes (350x).

    Control biobsy after 4 weeks:

    regular epithelium, regular glandular

    tubes. Moderate leucocyte

    infiltration, manifest reversal of

    inflammatory changes after 4 weeksof rectal ozone insufflation with 8,5-

    27 g/ml and 300 ml dayly, 3x perweek.

    (Knoch et al. Aktuelle Koloproktologie)

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    May 23, 2003 OZONOSAN 12

    MinorMinor AutoAuto Hemo TherapyHemo Therapy

    Indications

    - Allergies,

    - Acne, furunculosis,

    - Supportive cancer

    therapy

    by non specific activation of

    the immune system,

    general stimulation

    Extracorporeal blood

    treatment: 10 ml ozone with aconcentration of 1020 g/ml +

    2-3ml of patients own blood andintramuscular injection

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    May 23, 2003 OZONOSAN 13

    Topical FormsTopical Forms ofofApplicationApplication

    l Transcutaneous Ozone Gas Applicationin gas-tight and ozone-resistent plastic covers

    l Ozonized Waterin the form of spray or compresses

    Rectal O3-O2 Insufflation

    Intraarticular Injections

    Ozonized olive oil

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    May 23, 2003 OZONOSAN 14

    LocalLocal OzoneOzone--TreatmentTreatmentinin thethe form ofform of the low pressurethe low pressure system acc. to Werkmeistersystem acc. to Werkmeister

    Indications

    Decubitus ulcer

    Badly healing

    wounds

    Diabetic gangrene

    Burns

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    May 23, 2003 OZONOSAN 15

    Ozone Treatment

    in Surgery

    1915 A. Wolff

    1935 E. Payr

    1937 P. Aubourg

    1977 O. Rokitansky

    1981 H. Werkmeister,

    1987 H.G. Knoch,

    2002 Calderon, N.A.

    Kauffmann, T

    Werkmeister 1984

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    May 23, 2003 OZONOSAN 16

    The UseThe Use ofof Ozonized WaterOzonized Water inin thetheform of sprayform of spray or compressesor compresses

    Held, P

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    May 23, 2003 OZONOSAN 17

    SubcutanousSubcutanous,, intracutanousintracutanous

    andand intramuscularintramuscularinjectionsinjections 1979 Herget

    Gieen

    1999 Balkanyi

    Zrich

    Indications- Myotraumatic syndrome

    - Myogelosis

    eg in combination withtonanalgetic treatments

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    May 23, 2003 OZONOSAN 18

    Intraarticular InjectionsIntraarticular Injections inin OrthopedicsOrthopedics

    1981 Z. Fahmy,Bad Kreuznach, Germany

    1989 E. Riva-

    Sanseverino,Bologna, Italy

    Indications:- Knee arthrosis,- Gonarthrosis- and rheumatoid arthritis

    as supportive therapy

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    May 23, 2003 OZONOSAN 19

    MechanismMechanism of Action inof Action in TopicalTopical

    ApplicationsApplications1. Microbicidal Effects , ie

    bactericidal, fungicidal, virustatic

    2. Wound cleansing effect

    3. Wound healing effect

    4. Topical immunoactivation

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    May 23, 2003 OZONOSAN 20

    MechanismsMechanisms of Action in MAHof Action in MAH

    1. Activation of ImmunocompetentCells

    2. Activation of Red Blood CellMetabolism

    3. Activation and Induction ofBiological Antioxydants and

    Radical Scavengers

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    May 23, 2003 OZONOSAN 21

    immunomodu-

    lation, activ-

    ation of RBC-

    metabolism,in-

    crease of anti-

    oxidants

    ciculatory dis-

    orders,

    immuno-

    dysbalance

    revitalization,

    improvement of

    wound healing

    systemic

    treatment40

    30

    2o10

    germicidal,

    activation of

    cell metabolism

    badly healing

    wounds

    proctitis

    topical +system.

    application,

    limit for system.

    treatment

    60

    50

    germicidal

    wound -

    cleansing

    superinfected

    wounds

    colitis

    topical

    application

    100 g/ml

    9080

    70

    EfficacyIndicationApplicationConcentration

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    May 23, 2003 OZONOSAN 22

    ContraContra IndicationsIndications andand ApplicationsApplications

    Contra Indications

    1. Glucose-6 Phosphat- Dehydrogenase-

    Deficiency (Favism)

    2. HyperthyroidismContra Applications

    1. Intravenous Gas Injections

    2. Intraarteriel Gas Injections

    3. Hyperbaric Reinfusion