appointment reminder systems are effective but not optimal

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Appointment reminder systems are effective but not optimal: results of a systematic review and evidence synthesis employing realist principles MCLEAN, Sionnadh <http://orcid.org/orcid.org/0000-0002-9307-8565>, BOOTH, Andrew, GEE, Melanie <http://orcid.org/0000-0001-9149-4314>, SALWAY, Sarah, COBB, Mark, BHANBHRO, Sadiq <http://orcid.org/0000- 0003-0771-8130> and NANCARROW, Susan Available from Sheffield Hallam University Research Archive (SHURA) at: http://shura.shu.ac.uk/12139/ This document is the author deposited version. You are advised to consult the publisher's version if you wish to cite from it. Published version MCLEAN, Sionnadh, BOOTH, Andrew, GEE, Melanie, SALWAY, Sarah, COBB, Mark, BHANBHRO, Sadiq and NANCARROW, Susan (2016). Appointment reminder systems are effective but not optimal: results of a systematic review and evidence synthesis employing realist principles. Patient Preference and Adherence, 10, 479- 499. Copyright and re-use policy See http://shura.shu.ac.uk/information.html Sheffield Hallam University Research Archive http://shura.shu.ac.uk

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Page 1: Appointment reminder systems are effective but not optimal

Appointment reminder systems are effective but not optimal: results of a systematic review and evidence synthesis employing realist principles

MCLEAN, Sionnadh <http://orcid.org/orcid.org/0000-0002-9307-8565>, BOOTH, Andrew, GEE, Melanie <http://orcid.org/0000-0001-9149-4314>, SALWAY, Sarah, COBB, Mark, BHANBHRO, Sadiq <http://orcid.org/0000-0003-0771-8130> and NANCARROW, Susan

Available from Sheffield Hallam University Research Archive (SHURA) at:

http://shura.shu.ac.uk/12139/

This document is the author deposited version. You are advised to consult the publisher's version if you wish to cite from it.

Published version

MCLEAN, Sionnadh, BOOTH, Andrew, GEE, Melanie, SALWAY, Sarah, COBB, Mark, BHANBHRO, Sadiq and NANCARROW, Susan (2016). Appointment reminder systems are effective but not optimal: results of a systematic review and evidence synthesis employing realist principles. Patient Preference and Adherence, 10, 479-499.

Copyright and re-use policy

See http://shura.shu.ac.uk/information.html

Sheffield Hallam University Research Archivehttp://shura.shu.ac.uk

Page 2: Appointment reminder systems are effective but not optimal

© 2016 McLean et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further

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Patient Preference and Adherence 2016:10 479–499

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R e v i e w

open access to scientific and medical research

Open Access Full Text Article

http://dx.doi.org/10.2147/PPA.S93046

Appointment reminder systems are effective but not optimal: results of a systematic review and evidence synthesis employing realist principles

Sionnadh Mairi McLean1

Andrew Booth2

Melanie Gee3

Sarah Salway2

Mark Cobb4

Sadiq Bhanbhro3

Susan A Nancarrow5

1Faculty of Health and wellbeing, Sheffield Hallam University, Sheffield, UK; 2School of Health and Related Research, University of Sheffield, Sheffield, UK; 3Centre for Health and Social Care Research, Sheffield Hallam University, Sheffield, UK; 4Therapeutics & Palliative Care, Sheffield Teaching Hospitals, Sheffield, UK; 5School of Health and Human Science, Southern Cross University, east Lismore, NSw, Australia

Abstract: Missed appointments are an avoidable cost and resource inefficiency which impact

upon the health of the patient and treatment outcomes. Health care services are increasingly

utilizing reminder systems to manage these negative effects. This study explores the effectiveness

of reminder systems for promoting attendance, cancellations, and rescheduling of appointments

across all health care settings and for particular patient groups and the contextual factors which

indicate that reminders are being employed sub-optimally. We used three inter-related reviews

of quantitative and qualitative evidence. Firstly, using pre-existing models and theories, we

developed a conceptual framework to inform our understanding of the contexts and mechanisms

which influence reminder effectiveness. Secondly, we performed a review following Centre

for Reviews and Dissemination guidelines to investigate the effectiveness of different methods

of reminding patients to attend health service appointments. Finally, to supplement the effec-

tiveness information, we completed a review informed by realist principles to identify factors

likely to influence non-attendance behaviors and the effectiveness of reminders. We found

consistent evidence that all types of reminder systems are effective at improving appointment

attendance across a range of health care settings and patient populations. Reminder systems

may also increase cancellation and rescheduling of unwanted appointments. “Reminder plus”,

which provides additional information beyond the reminder function may be more effective than

simple reminders (ie, date, time, place) at reducing non-attendance at appointments in particular

circumstances. We identified six areas of inefficiency which indicate that reminder systems are

being used sub-optimally. Unless otherwise indicated, all patients should receive a reminder

to facilitate attendance at their health care appointment. The choice of reminder system should

be tailored to the individual service. To optimize appointment and reminder systems, health

care services need supportive administrative processes to enhance attendance, cancellation,

rescheduling, and re-allocation of appointments to other patients.

Keywords: attendance, cancellation, rescheduling, TURNUP

IntroductionMissed health care appointments are a major source of avoidable inefficiency that

impacts on patient health and treatment outcomes. Data on non-attendance vary,

however studies from around the world consistently report non-attendance rates of

between 15% and 30% in outpatient health clinics.1–4 In England, more than 12 million

appointments at consultant led clinics,5 and a similar number of general practice

appointments are missed each year.6 The cost of missed appointments to the UK

National Health Service (NHS) has tripled since 1999.7 In 2009, non-attendance was

estimated to cost over £600 million (around US$970 million).8

Correspondence: Sionnadh Mairi McLeanCollegiate Campus, Sheffield Hallam University, 38 Collegiate Crescent, Sheffield, S10 2BP, UKTel +44 114 225 2271email [email protected]

Journal name: Patient Preference and AdherenceArticle Designation: ReviewYear: 2016Volume: 10Running head verso: McLean et alRunning head recto: Effectiveness and optimization of appointment remindersDOI: http://dx.doi.org/10.2147/PPA.S93046

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McLean et al

The consequences of non-attendance include increased

appointment waiting times,9 increased costs of care delivery,10,11

underutilization of equipment and personnel,10 reduced

appointment availability,6,11 reduced patient satisfaction,12,13

and negative relationships between patients and staff.6,9 Missed

appointments may delay presentation at health services, result-

ing in a lack of follow-up of chronic conditions which may

ultimately lead to complications, unnecessary suffering, and

costly hospital admission.10,14 Pressures from referring agents

to manage waiting lists, can potentially increase staff stress,

anxiety, and fatigue levels.15 Reducing the number of missed

appointments may be a relatively inexpensive way to increase

health care efficiency, effectiveness, and quality.

Numerous reviews have demonstrated the effectiveness

of existing reminder systems in varied service settings.

However, research to-date focusses on the use of reminder

systems in particular service contexts or technologies,16–18

rather than synthesizing knowledge across different contexts

and patient groups. This study explores the effectiveness of

reminder systems for promoting attendance, cancellations,

and rescheduling of appointments across all health care set-

tings and for particular patient groups and the contextual

factors which indicate that reminders are being employed

sub-optimally.

Material and methodsOur project incorporated three components: the development

of a conceptual framework to provide an understanding of

the contexts and mechanisms which influence reminder

effectiveness (review 1); a systematic review (SR) of the

reminder effectiveness literature (review 2), and an evi-

dence synthesis informed by realist principles to explain

the contexts and mechanisms which influence reminder

effectiveness (review 3). We used realist inquiry because it

clarifies the context–mechanism–outcome relationships in an

attempt to understand better what works, for whom, under

what circumstances.19 Further detail on the methodology

employed is available in the TURNUP project report.20

Searches were conducted on 13 databases with date

limits of January 1, 2000 to February 15, 2012: AMED,

CINAHL Plus with Full Text, Cochrane Library, Embase,

HMIC, IEEE Xplore, Kings Fund Library Catalogue,

Maternity and Infant Care, MEDLINE, PEDro, PsycINFO,

SportDiscus, and Web of Science. The strategy used the

concept of (reminders/prompts/alerts) in proximity to

(appointments) (Figure 1). Where supported, appropriate

database headings/thesaurus terms were used. The refer-

ence lists of included randomized controlled trials (RCTs)

and SRs were screened for additional relevant studies and

citation (forward-) searches were performed in respect of

the included RCTs. English-language studies of various

quantitative and qualitative designs were included if they

investigated the effectiveness of outpatient appointment

reminders, appointment attendance behavior, or explicated

theories/models/frameworks relating to reminder systems

or appointment attendance. Studies were excluded if they

investigated reminders sent to a patient inviting them to

schedule an appointment. All members of the project team

were involved in screening and selection of studies and data

extraction from included studies.

Review 1We could find few pre-existing conceptual models or

frameworks that directly explain the mechanisms by which

CitationsS1 (MH “Reminder Systems”) 2,850S2 TI reminder* OR AB reminder* 8,104S3 TI appointment* OR AB appointment* 18,257S4 (MH “Appointments and Schedules”) 10,007S5 s3 OR s4 25,901S6 s5 AND s1 409S7 s1 OR s2 9,797S8 s7 AND s4 452S9 s6 OR s8 543S10 TI remind* n5 appointment* OR AB remind* n5 appointment* 277S11 TI prompt* n5 appointment* OR AB prompt* n5 appointment* 34S12 TI alert* n5 appointment* OR AB alert* n5 appointment* 6S13 S10 OR S11 OR S12 316S14 S9 OR S13 limiters – published date from: 20000101- 470

Figure 1 example search strategy.Note: example search strategy: CiNAHL Plus with Fulltext, MeDLiNe, SportDiscus (via eBSCO) 2000 to January 11, 2012.

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effectiveness and optimization of appointment reminders

reminder systems support appointment attendance.

We therefore drew on a variety of models that have been

developed to understand behavior in relation to medical

adherence. Included models related to use of reminders to

promote clinical outcomes;21 health care utilization theory;22

the theory of planned behavior;23 the trans-theoretical

model;24 self-determination theory;25 protection motivation

theory;26 rationale choice theory;27 and complexity theory.28

Our conceptual framework was developed through an itera-

tive process involving examination of the various theories

and discussions about context, mechanisms, and outcomes

that were important to explain how reminder systems work

to promote attendance, for whom, and in what circumstances.

The framework consisted of six broad factors that could

potentially influence the effectiveness of the reminder or

whether patients would attend, cancel or reschedule their

appointment, namely: the reminder-patient interaction,

reminder accessibility, health care settings, wider social

factors, cancellation and rebooking systems, and patient

attributes. This framework was then used to support data

extraction.

Review 2Our SR of effectiveness investigated the impact of reminder

systems on improvements in attendance, cancellations, and

rescheduling of appointments. The questions addressed in

this were: 1) how effective are reminder systems at reducing

non-attendance at appointments and increasing cancellation/

rescheduling of appointments? and 2) which types of reminder

systems are most effective in improving the uptake of health

service appointments? We used standardized methods to select,

quality assess, extract and synthesize the findings of SRs and

RCTs.29 The Critical Appraisal Skills Program appraisal tool

for RCTs was used to quality assess those RCTs not already

assessed in pre-existing SRs.30 The quality of the included

SRs was assessed against the criteria used by the Centre for

Reviews and Dissemination when evaluating reviews for

inclusion in the Database of Abstracts of Reviews of Effects.31

We used these quality assessments to moderate our interpreta-

tion of the review findings, not to exclude the papers.32

Review 3Our evidence synthesis aimed to explore the differential

effectiveness of reminder systems for particular population

sub-groups; to identify contexts and mechanisms which

influence the effectiveness of different reminder systems

for particular population sub-groups; and identify any

disadvantages which should be considered when introducing

reminder systems for specific populations. The data extrac-

tion framework used the six elements of the conceptual

framework. In accordance with realist principles, not all

potentially relevant papers identified from the screening con-

tributed to the synthesis.33 All RCTs investigating reminder

systems and all reviews (systematic and otherwise) about

reminder systems and appointment systems were prioritized

for full extraction of contextual and explanatory variables.

Whereas RCTs were required to meet minimum quality

standards in order to be included in the effectiveness SR,

the studies excluded from this SR still had the potential

to contribute to the evidence synthesis informed by realist

principles. In many cases findings from such studies con-

tributed to the evidence base regarding the mechanisms and

contexts that shape the operation of reminder systems in

real world settings. Examination of the trial evidence was fol-

lowed by exploration of qualitative, mixed-methods and non-

RCT quantitative studies about reminders and appointments

for Europe, America, Canada, Australia, and New Zealand.

Thematic analysis was used to examine the evidence avail-

able for each section of the framework. Subsequently a

narrative synthesis was developed that sought to explain the

context and mechanisms influencing how reminders support

attendance, cancellation, and rebooking.

ResultsThe PRISMA (Preferred Reporting Items for Systematic

Reviews and Meta-Analyses) flowchart (Figure 2) shows

the numbers of included papers for review 2 and 3. Prelimi-

nary database searches yielded 638 unique papers; a further

139 were identified from subsequent searches. Following

the screening stages, 466 potentially relevant papers were

identified. Eleven SRs met the inclusion criteria for review 2

(Table 1).16–18,34–41 These SRs either examined a single tech-

nology, eg, an SR of short message service (SMS) reminder

systems,17 or explored the role of information technologies

along a patient care pathway, one of which might be appoint-

ment reminder systems.41 The quality of included reviews

was variable (Table 2). The five Cochrane reviews had been

scrutinized against the highest quality standards.16,18,34,36,40

Four reviews passed the Centre for Reviews and Dissemina-

tion SR quality threshold.17,35,39,41 Two reviews did not pass

the minimum standard for SRs.37,38

Of the 31 RCTs that met our inclusion criteria for

review2,4,42–72 only ten were uniquely identified by our

review. The included RCTs related to the use of systems

to remind patients to attend a health-related appointment

that had already been scheduled (Table 3). The majority of

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Figure 2 PRISMA flowchart for review 2 and 3.Abbreviations: PRiSMA, Preferred Reporting items for Systematic Reviews and Meta-Analyses; SRs, systematic reviews; RCTs, randomized controlled trials; Ti, titles; AB, abstracts.

Table 1 Reminder technologies covered by each review

Study Letter Manual telephone

Automated telephone

Mobile/SMS Voice messaging

Email Other

Atherton et al18 Car et al34 Free et al35 Glynn et al36

Guy et al17 Hasvold and wootton37 Henderson38 Jacobson vann and Szilagyi16 Krishna et al39 Reda and Makhoul40 Personal visitStubbs et al41 Open access

scheduling

Abbreviation: SMS, short message service.

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effectiveness and optimization of appointment reminders

Tab

le 2

Rev

iew

s in

clud

ed in

thi

s re

view

with

an

asse

ssm

ent

of t

heir

qua

lity

Stud

yR

evie

w q

uest

ion/

aim

sO

vera

ll re

view

qua

lity

Impl

icat

ions

for

tech

nolo

gies

Impl

icat

ions

for

spec

ific

popu

lati

ons

Ath

erto

n

et a

l18

To a

sses

s ef

fect

s of

usin

g em

ail

for

coor

dina

tion

of h

ealth

car

e ap

poin

tmen

ts a

nd a

tten

danc

e re

min

ders

, com

pare

d to

ot

her

form

s of

coo

rdin

atin

g ap

poin

tmen

ts a

nd r

emin

ders

, on

outc

omes

for

heal

th p

rofe

ssio

nals,

pa

tient

s an

d ca

rers

, and

hea

lth

serv

ices

, inc

ludi

ng h

arm

s.

Coc

hran

e em

pty

Rev

iew

with

no

elig

ible

stu

dies

. A

lim

itatio

n of

thi

s re

view

is t

he d

ate

of t

he s

earc

h.

The

sea

rch

was

con

duct

ed in

Janu

ary

2010

. Len

gth

of t

ime

betw

een

sear

ch d

ate

and

publ

icat

ion

of

revi

ew m

eans

it is

pos

sibl

e th

at r

elev

ant

stud

ies

have

be

en p

ublis

hed

in in

teri

m p

erio

d.

Not

app

licab

leN

ot a

pplic

able

Car

et

al34

To

asse

ss e

ffect

s of

mob

ile

phon

e m

essa

ging

rem

inde

rs

for

atte

ndan

ce a

t he

alth

car

e ap

poin

tmen

ts. S

econ

dary

ob

ject

ives

incl

ude

asse

ssm

ent

of

patie

nt a

nd h

ealth

car

e pr

ovid

er

eval

uatio

ns o

f int

erve

ntio

n; c

osts

; an

d po

ssib

le r

isks

and

har

ms

asso

ciat

ed w

ith in

terv

entio

n.

Coc

hran

e R

evie

w. i

nclu

ded

stud

ies

wer

e of

var

ying

m

etho

dolo

gica

l qua

lity;

mos

t pr

ovid

ed in

suffi

cien

t in

form

atio

n to

acc

urat

ely

asse

ss r

isk

of b

ias.

Se

quen

ce g

ener

atio

n fo

r ra

ndom

izat

ion

cons

ider

ed

adeq

uate

(al

thou

gh r

ando

miz

atio

n m

etho

d un

clea

r in

one

stu

dy)

but

in t

wo

stud

ies

it w

as n

ot c

lear

w

heth

er, a

nd h

ow, a

lloca

tion

was

con

ceal

ed. L

ack

of b

lindi

ng in

all

stud

ies

can

be p

artly

exp

lain

ed b

y in

tera

ctiv

e na

ture

of t

ext

mes

sage

inte

rven

tions

, w

hich

doe

s no

t pe

rmit

blin

ding

of p

artic

ipan

ts o

r he

alth

car

e pr

ovid

ers.

Pot

entia

l bia

s fr

om a

ppar

ent

lack

of b

lindi

ng o

f out

com

e as

sess

ors.

incl

uded

4 R

CT

s in

volv

ing

3,54

7 pa

rtic

ipan

ts.

Thr

ee s

tudi

es w

ith m

oder

ate

qual

ity e

vide

nce

show

ed

that

mob

ile t

ext

mes

sage

rem

inde

rs im

prov

ed r

ate

of

atte

ndan

ce c

ompa

red

to n

o re

min

ders

(R

R 1

.10

[9

5% C

i] 1.

03 t

o 1.

17).

One

low

qua

lity

stud

y re

port

ed th

at m

obile

text

m

essa

ge r

emin

ders

with

pos

tal r

emin

ders

, com

pare

d to

pos

tal r

emin

ders

, impr

oved

rat

e of

att

enda

nce

at h

ealth

car

e ap

poin

tmen

ts (R

R 1.

10 [9

5% C

i 1.0

2 to

1.1

9]).

How

ever

, tw

o st

udie

s of

mod

erat

e qu

ality

sh

owed

that

mob

ile p

hone

text

mes

sage

rem

inde

rs

and

phon

e ca

ll re

min

ders

had

a s

imila

r im

pact

on

heal

th c

are

atte

ndan

ce (R

R 0.

99 [9

5% C

i] 0.

95 to

1.0

3).

Cos

ts/a

tten

danc

e of

SM

S lo

wer

com

pare

d to

pho

ne

rem

inde

rs. N

o st

udie

s re

port

ed h

arm

s or

adv

erse

ef

fect

s of

the

inte

rven

tion,

nor

hea

lth o

utco

mes

or

user

per

cept

ion

of s

afet

y re

late

d to

the

inte

rven

tion.

Furt

her

rese

arch

sho

uld

focu

s on

old

er

patie

nts,

giv

en t

hat

this

pop

ulat

ion

has,

on

aver

age,

mor

e he

alth

car

e ap

poin

tmen

ts a

nd u

ses

mob

ile p

hone

s le

ss fr

eque

ntly

tha

n th

e yo

unge

r po

pula

tion.

Free

et

al35

To

quan

tify

effe

ctiv

enes

s of

m

obile

tec

hnol

ogy

base

d in

terv

entio

ns d

eliv

ered

to

heal

th

care

pro

vide

rs o

r to

sup

port

he

alth

car

e se

rvic

es, o

n an

y he

alth

or

heal

th c

are

serv

ice

outc

ome.

Iden

tified

as

mee

ting

CR

D c

rite

ria.

No

full

eval

uatio

n ye

t av

aila

ble.

Pool

ed e

ffect

on

appo

intm

ent a

tten

danc

e us

ing

text

m

essa

ge (S

MS)

rem

inde

rs v

s no

rem

inde

r in

crea

sed,

w

ith R

R of

1.0

6 (9

5% C

i 1.0

5–1.

07, I2 =

6%).

Pool

ed

effe

cts

on n

umbe

r of

can

celle

d ap

poin

tmen

ts w

as n

ot

signi

fican

tly in

crea

sed

RR 1

.08

(95%

CI 0

.89–

1.30

). N

o di

ffere

nce

in a

tten

danc

e us

ing

SMS

rem

inde

rs

vs o

ther

rem

inde

rs (R

R 0.

98, 9

5% C

i 0.9

4–1.

02,

resp

ectiv

ely)

. SM

S re

min

ders

no

mor

e ef

fect

ive

than

po

stal

or

phon

e ca

ll re

min

ders

, and

text

ing

rem

inde

rs to

pa

tient

s w

ho p

ersis

tent

ly m

issed

app

oint

men

ts d

id n

ot

signi

fican

tly c

hang

e nu

mbe

r of

can

celle

d ap

poin

tmen

ts.

SMS

appo

intm

ent r

emin

ders

hav

e m

odes

t ben

efits

and

m

ay b

e ap

prop

riate

for

impl

emen

tatio

n.

(Con

tinue

d)

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McLean et al

Tab

le 2

(Co

ntin

ued)

Stud

yR

evie

w q

uest

ion/

aim

sO

vera

ll re

view

qua

lity

Impl

icat

ions

for

tech

nolo

gies

Impl

icat

ions

for

spec

ific

popu

lati

ons

Gly

nn

et a

l36

To

eval

uate

the

effe

ctiv

enes

s of

rem

inde

rs o

n im

prov

ing

the

follo

w-u

p of

pat

ient

s w

ith

hype

rten

sion

.

Coc

hran

e R

evie

w. i

nclu

ded

RC

Ts

with

a

cont

empo

rane

ous

cont

rol g

roup

. The

met

hodo

logi

cal

qual

ity o

f inc

lude

d st

udie

s w

as g

ener

ally

poo

r to

m

oder

ate

with

40%

of i

nclu

ded

artic

les

desc

ribi

ng

thei

r ra

ndom

izat

ion

proc

esse

s an

d on

ly 1

9%

desc

ribi

ng a

dequ

ate

conc

eale

d al

loca

tion

proc

esse

s.

incl

uded

8 R

CT

s in

vest

igat

ing

appo

intm

ent

rem

inde

r sy

stem

s. A

ll bu

t on

e of

the

RC

Ts

wer

e as

soci

ated

w

ith im

prov

ed o

utco

mes

. The

poo

led

resu

lts fa

vore

d ap

poin

tmen

t re

min

der

syst

ems

for

follo

w-u

p of

pa

tient

s (o

dds

ratio

of b

eing

lost

to

follo

w-u

p 0.

4,

95%

Ci 0

.3 t

o 0.

5).

Guy

et

al17

To

asse

ss t

he e

ffect

iven

ess

of

SMS

rem

inde

rs a

t in

crea

sing

the

up

take

of a

ppoi

ntm

ents

in h

ealth

ca

re s

ettin

gs.

Alth

ough

gra

y lit

erat

ure

was

sea

rche

d, it

was

stil

l po

ssib

le t

hat

som

e ev

alua

tions

wer

e no

t id

entifi

ed,

part

icul

arly

tho

se w

ith a

neg

ativ

e ou

tcom

e. U

nabl

e to

ass

ess

poss

ibili

ty o

f effe

ct a

ccor

ding

to

clin

ical

re

ason

s fo

r at

tend

ing,

as

few

pap

ers

pres

ente

d th

is in

form

atio

n. C

linic

al p

rese

ntat

ion

coul

d af

fect

pr

iori

ty p

lace

d by

pat

ient

s on

the

nee

d fo

r ke

epin

g an

app

oint

men

t.T

o m

axim

ize

valu

e of

futu

re e

valu

atio

ns, s

tudi

es

shou

ld c

olle

ct a

nd r

epor

t in

form

atio

n on

clin

ical

re

ason

for

atte

ndan

ce a

s w

ell a

s th

e vi

sit

stat

us

(new

, fol

low

-up)

.

Sum

mar

y ef

fect

from

RC

Ts

was

1.4

8 (9

5% C

i: 1.

23–1

.72)

. No

sign

ifica

nt s

ub-g

roup

diff

eren

ces

by

clin

ic t

ype

(pri

mar

y ca

re c

linic

s, h

ospi

tal o

utpa

tient

cl

inic

s) o

r m

essa

ge t

imin

g (2

4, 4

8, a

nd 7

2+ h

ours

be

fore

sch

edul

ed a

ppoi

ntm

ent)

.SM

S re

min

ders

sub

stan

tially

incr

ease

like

lihoo

d of

at

tend

ing

clin

ic a

ppoi

ntm

ents

. SM

S re

min

ders

app

ear

to b

e si

mpl

e an

d ef

ficie

nt o

ptio

n fo

r he

alth

ser

vice

s to

impr

ove

serv

ice

deliv

ery,

as

wel

l as

brin

ging

hea

lth

bene

fits

for

patie

nts

who

rec

eive

the

rem

inde

rs.

No

sign

ifica

nt s

ub-g

roup

diff

eren

ces

by

targ

et a

ge g

roup

(pe

diat

ric,

adul

t, ol

der)

. A

ge c

lass

ifica

tion

base

d on

med

ian

age

of p

atie

nt r

ecei

ving

SM

S re

min

ders

, or

spec

ifica

tion

of c

linic

typ

e as

ped

iatr

ic.

RC

Ts

dem

onst

rate

d SM

S re

min

ders

ef

fect

ive

in w

ide

age

rang

e fr

om

pedi

atri

c to

old

er. M

obile

usa

ge

data

dem

onst

rate

tha

t ov

er 9

0% o

f po

pula

tion

in m

any

coun

trie

s ow

n m

obile

pho

nes,

but

upta

ke is

hig

her

in

youn

ger

peop

le.86

As

youn

ger

patie

nts

have

hig

her

non-

atte

ndan

ce r

ates

at

clin

ical

ser

vice

s,10

0 SM

S re

min

ders

m

ay b

e m

ore

bene

ficia

l in

this

gr

oup.

How

ever

, old

er p

atie

nts

have

co

nsid

erab

ly m

ore

heal

th a

ppoi

ntm

ents

ea

ch y

ear,

ofte

n at

out

patie

nt c

linic

s w

here

non

-att

enda

nce

cost

s U

K N

HS

estim

ated

£79

0 m

illio

n pe

r ye

ar.10

1

Has

vold

and

w

oott

on37

1) w

hat

is t

he b

est

estim

ate

of

effe

ct o

f sen

ding

rem

inde

rs

on n

on-a

tten

danc

e ra

tes?

2) A

re t

here

any

diff

eren

ces

in

non-

atte

ndan

ce w

hen

usin

g re

min

ders

sen

t m

anua

lly (

ie,

from

pho

nes

oper

ated

by

a hu

man

) or

aut

omat

ical

ly (

ie,

by S

MS

text

mes

sage

s or

by

auto

mat

ed v

oice

rec

ordi

ngs)

?3)

Doe

s tim

e at

whi

ch t

he

rem

inde

r is

sen

t in

fluen

ce

the

effe

ct o

n no

n- a

tten

danc

e ra

tes?

4) W

hat

are

cost

s an

d be

nefit

s of

us

ing

rem

inde

rs?

Not

cla

ssed

as

syst

emat

ic r

evie

w b

y D

AR

e (C

RD

). Pu

bMed

onl

y se

arch

ed.

wei

ghte

d m

ean

rela

tive

chan

ge in

non

-att

enda

nce

was

34%

of b

asel

ine

non-

atte

ndan

ce r

ate.

Aut

omat

ed r

emin

ders

less

effe

ctiv

e th

an m

anua

l ph

one

calls

(29

% v

s 39

% o

f bas

elin

e va

lue)

.N

o di

ffere

nce

in n

on-a

tten

danc

e ra

te, w

heth

er

rem

inde

r se

nt d

ay b

efor

e or

wee

k be

fore

.C

ost

and

savi

ngs

not

mea

sure

d fo

rmal

ly, b

ut a

lmos

t ha

lf in

clud

ed c

ost

estim

ates

. Ave

rage

cos

t of

usi

ng

eith

er S

MS,

aut

omat

ed p

hone

cal

ls o

r ph

one

calls

was

0.

41 e

uros

per

rem

inde

r.

All

stud

ies

exce

pt o

ne10

2 sho

wed

po

sitiv

e ef

fect

from

usin

g re

min

ders

. (P

atie

nts

them

selv

es c

hose

in a

dvan

ce

whe

ther

the

y w

ished

to

rece

ive

rem

inde

r or

not

– p

oten

tial b

ias

in

inte

rven

tion

grou

p.) O

vera

ll no

-sh

ow r

ate

(out

patie

nts

in v

ascu

lar

labo

rato

ry) w

as 1

2% (a

vera

ge 7

.6

miss

ed a

ppoi

ntm

ents

/wee

k: gr

oss

annu

al

reve

nue

loss

of U

S$89

,107

bas

ed o

n ul

tras

ound

cos

ts).

Of 8

,766

pat

ient

s of

fere

d au

tom

ated

rem

inde

rs, o

nly

53%

agr

eed

to r

ecei

ve c

alls.

No-

show

ra

te s

igni

fican

tly g

reat

er fo

r pa

tient

s ch

oosin

g au

tom

ated

rem

inde

rs

(8.9

% v

s 5.

9%, P

,0.

0001

).

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485

effectiveness and optimization of appointment reminders

Hen

ders

on38

To

asse

ss t

he e

ffect

iven

ess

of

appo

intm

ent

rem

inde

rs a

s a

mea

ns o

f inc

reas

ing

atte

ndan

ce

and

redu

cing

DN

A r

ates

at

new

ou

tpat

ient

app

oint

men

ts.

Not

cla

ssed

as

syst

emat

ic r

evie

w b

y D

AR

e (C

RD

). U

nder

take

n by

sin

gle

revi

ewer

, with

pos

sibi

lity

of r

evie

wer

bia

s. H

and-

sear

chin

g no

t pe

rfor

med

. N

on-e

nglis

h la

ngua

ge p

aper

s no

t in

clud

ed. R

elev

ant

mat

eria

l may

hav

e be

en m

isse

d.M

etho

dolo

gica

l qua

lity

of e

vide

nce

base

gen

eral

ly

poor

. Sev

eral

tri

als

faile

d to

des

crib

e ra

ndom

izat

ion.

in

man

y st

udie

s bl

indi

ng w

as p

oorl

y ad

dres

sed,

stu

dy

part

icip

ants

wer

e in

adeq

uate

ly d

escr

ibed

and

onl

y a

smal

l num

ber

of p

artic

ipan

ts w

ere

recr

uite

d.

Tel

epho

ne r

emin

ders

, if r

ecei

ved,

can

hav

e a

posi

tive

impa

ct o

n at

tend

ance

and

DN

A r

ates

.Po

stal

rem

inde

rs fo

und

to b

e ef

fect

ive.

Alth

ough

lim

ited,

lite

ratu

re s

ugge

sts

that

the

impa

ct o

f “s

tand

ard”

rem

inde

rs is

sim

ilar

to t

hat

of t

elep

hone

re

min

ders

. Sug

gest

s th

at “

Rem

inde

r pl

us”

is m

ore

effe

ctiv

e th

an “

stan

dard

” re

min

ders

.

impa

ct o

f im

plem

entin

g in

itiat

ives

on

ineq

ualit

ies

in a

cces

s to

ser

vice

s no

t co

nsid

ered

by

any

stud

ies

incl

uded

in

revi

ew.

Maj

ority

of i

nclu

ded

stud

ies

cond

ucte

d in

psy

chia

tric

set

tings

out

side

the

UK

, ra

isin

g is

sues

of g

ener

aliz

abili

ty.

Jaco

bson

v

ann

and

Szila

gyi16

To

asse

ss o

vera

ll ef

fect

iven

ess

of p

atie

nt r

emin

der

or r

ecal

l sy

stem

s, o

r bo

th, i

n im

prov

ing

imm

uniz

atio

n ra

tes;

com

pare

ef

fect

iven

ess

of d

iffer

ent

type

s of

re

min

der

or r

ecal

l int

erve

ntio

ns

(eg,

pos

tcar

d, le

tter

, tel

epho

ne),

or c

ombi

natio

n of

bot

h re

min

der

and

reca

ll.

Coc

hran

e R

evie

w.

Rem

indi

ng p

eopl

e ov

er t

elep

hone

, sen

ding

a le

tter

or

pos

tcar

d, o

r sp

eaki

ng t

o th

em in

per

son

incr

ease

d va

ccin

atio

ns. P

rovi

ding

num

erou

s re

min

ders

was

m

ore

effe

ctiv

e th

an s

ingl

e re

min

ders

. Rem

indi

ng

peop

le o

ver

tele

phon

e m

ore

effe

ctiv

e th

an p

ostc

ard

or le

tter

rem

inde

rs. R

emin

ders

ove

r te

leph

one

may

be

exp

ensi

ve c

ompa

red

with

alte

rnat

ive

appr

oach

es.

Rem

inde

rs w

orke

d w

heth

er fr

om p

riva

te d

octo

r’s

offic

e, m

edic

al c

ente

r, o

r pu

blic

hea

lth d

epar

tmen

t cl

inic

. Stu

dies

all

from

dev

elop

ed c

ount

ries

.

Rem

indi

ng p

eopl

e to

hav

e va

ccin

atio

ns

incr

ease

d th

e nu

mbe

r of

peo

ple

vacc

inat

ed, w

heth

er t

he p

eopl

e w

ere

due

or o

verd

ue fo

r va

ccin

atio

ns.

incr

ease

s w

ere

obse

rved

in b

oth

child

ren

and

adul

ts fo

r al

l typ

es

of v

acci

nes,

but

not

am

ong

urba

n ad

oles

cent

s in

one

stu

dy.

Kri

shna

et

al39

To

inve

stig

ate

role

of c

ell p

hone

s an

d te

xt m

essa

ging

inte

rven

tions

in

impr

ovin

g he

alth

out

com

es a

nd

proc

esse

s of

car

e.

Res

earc

h qu

estio

n su

ppor

ted

by in

clus

ion

crite

ria

for

stud

y de

sign

, int

erve

ntio

n an

d ou

tcom

es.

Aut

hors

did

not

rep

ort

sear

ches

of u

npub

lishe

d da

ta. O

nly

stud

ies

publ

ishe

d in

eng

lish/

engl

ish-

lang

uage

abs

trac

ts e

ligib

le fo

r in

clus

ion.

Pub

licat

ion/

lang

uage

bia

s co

uld

not

be r

uled

out

. Aut

hors

did

no

t re

port

rev

iew

pro

cess

, so

not

know

n w

heth

er

step

s ta

ken

to r

educ

e po

ssib

le e

rror

and

bia

s (s

uch

as p

erfo

rmin

g pr

oces

ses

in d

uplic

ate)

. Stu

dy

qual

ity n

ot a

sses

sed,

so

unkn

own

whe

ther

res

ults

of

incl

uded

stu

dies

wer

e re

liabl

e. M

any

stud

ies

had

smal

l sam

ple

size

s. N

arra

tive

synt

hesi

s w

as

appr

opri

ate

give

n di

vers

ity o

f inc

lude

d st

udie

s.

Due

to

poss

ibili

ty o

f bia

s an

d er

ror

in r

evie

w

proc

ess

and

unkn

own

qual

ity o

f inc

lude

d st

udie

s,

auth

ors’

con

clus

ions

may

not

be

relia

ble.

Tex

t m

essa

ging

ass

ocia

ted

with

few

er d

ays

to

diag

nosi

s (o

ne s

tudy

). Fa

ilure

-to-

atte

nd r

ates

si

gnifi

cant

ly im

prov

ed in

tw

o st

udie

s, b

ut d

id n

ot d

iffer

si

gnifi

cant

ly b

etw

een

inte

rven

tion/

cont

rol g

roup

s in

tw

o ot

her

stud

ies.

Mob

ile p

hone

rem

inde

r, d

isea

se

mon

itori

ng a

nd m

anag

emen

t, an

d ed

ucat

ion

can

impr

ove

heal

th o

utco

mes

and

car

e pr

oces

ses.

Text

mes

sagi

ng a

ssoc

iate

d w

ith

impr

oved

com

mun

icat

ion

in p

artic

ipan

ts

with

dis

abili

ties

(one

stu

dy).

Red

a an

d M

akho

ul40

To

estim

ate

the

effe

cts

of s

impl

e pr

ompt

ing

by p

rofe

ssio

nal c

arer

sto

enc

oura

ge a

tten

danc

e at

cl

inic

s fo

r th

ose

with

sus

pect

ed

seri

ous

men

tal i

llnes

s.

Coc

hran

e R

evie

w.

No

clea

r di

ffere

nce

betw

een

thos

e pr

ompt

ed b

y te

leph

one

1 or

2 d

ays

befo

re a

ppoi

ntm

ent v

s th

ose

give

n st

anda

rd a

ppoi

ntm

ent m

anag

emen

t sys

tem

(2

RC

Ts, n

=457

, RR

miss

ed a

ppoi

ntm

ent 0

.84

95%

C

i 0.7

–1.1

). Tex

t-ba

sed

prom

pts

such

as

a le

tter

, a fe

w

days

bef

ore

the

appo

intm

ent d

ay, m

ay in

crea

se c

linic

at

tend

ance

vs

indi

catio

n th

at fo

r se

riou

s m

enta

l illn

ess

it m

ay b

e im

port

ant

to p

rovi

de t

extu

al

rem

inde

r pl

us o

rien

tatio

n st

atem

ent

(a

sho

rt p

arag

raph

, tak

ing

abou

t

30 se

cond

s to

read

, exp

laini

ng th

e pr

ogra

m

of c

are,

the

fee

syst

em, a

nd p

rovid

ing

(Con

tinue

d)

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486

McLean et al

Tab

le 2

(Co

ntin

ued)

Stud

yR

evie

w q

uest

ion/

aim

sO

vera

ll re

view

qua

lity

Impl

icat

ions

for

tech

nolo

gies

Impl

icat

ions

for

spec

ific

popu

lati

ons

no p

rom

pt (3

RC

Ts, n

=326

, RR

miss

ed a

ppoi

ntm

ent 0

.76

95%

Ci 0

.43–

1.32

). O

ne s

mal

l stu

dy (n

=61)

com

bine

d te

leph

one/

text

-bas

ed p

rom

pts

vs n

o pr

ompt

, no

real

di

ffere

nce

betw

een

grou

ps (R

R m

issed

app

oint

men

t 0.

7 95

% C

i 0.4

–1.2

). Tel

epho

ne p

rom

pts

vs te

xt-b

ased

pr

ompt

s (1

RC

T, n=

75),

the

latt

er, a

s an

“orie

ntat

ion

stat

emen

t” m

ay b

e m

ore

effe

ctiv

e th

an te

leph

one

prom

pt (R

R m

issed

app

oint

men

t 1.9

95%

Ci 0

.98–

3.8)

. O

ne s

tudy

(n=1

20) c

ompa

red

stan

dard

lett

er p

rom

pt

vs a

lett

er o

rient

atio

n st

atem

ent.

Ove

rall,

resu

lts te

nded

to

favo

r or

ient

atio

n st

atem

ent v

s sim

ple

lett

er b

ut n

ot

stat

istic

ally

sig

nific

ant (

RR m

issed

app

oint

men

t 1.6

95%

C

i 0.9

–2.9

). Fo

r pr

ompt

s re

gard

less

of t

ype,

resu

lts o

f gr

eate

r sig

nific

ance

sug

gest

incr

ease

d at

tend

ance

(RR

m

issed

app

oint

men

t 0.8

0 95

% C

i 0.6

5–0.

98).

gent

le e

ncou

rage

men

t).65

Con

tras

ts

with

gen

eral

tren

d in

favo

r of

tele

phon

e re

min

ders

.

Stub

bs

et a

l41

To

com

pare

tel

epho

ne, m

ail,

text

/SM

S, e

lect

roni

c m

ail

and

open

-acc

ess

sche

dulin

g to

det

erm

ine

whi

ch is

bes

t at

red

ucin

g ou

tpat

ient

non

-at

tend

ance

and

pro

vidi

ng n

et

finan

cial

ben

efit.

Revi

ew a

ddre

ssed

bro

ad r

esea

rch

ques

tion

to e

valu

ate

impa

ct o

f all

met

hods

for

redu

cing

out

patie

nt n

on-

atte

ndan

ce. M

etho

ds u

sed

to id

entif

y an

d se

lect

stu

dies

fo

r in

clus

ion

gene

rally

cle

ar, b

ut p

ublic

atio

n bi

as c

anno

t be

rul

ed o

ut. N

o at

tem

pts

to a

sses

s st

udy

qual

ity o

r m

inim

ize

erro

rs a

nd b

ias

in r

evie

w p

roce

ss m

entio

ned.

incl

uded

stu

dies

ext

rem

ely

dive

rse

in p

opul

atio

ns,

sett

ings

, and

res

earc

h m

etho

ds. A

naly

sis b

ased

on

simpl

e w

eigh

ted

aver

age

for

each

app

roac

h (t

elep

hone

, te

xt, p

ost,

or o

pen

acce

ss).

Influ

ence

of o

ther

rel

evan

t fa

ctor

s on

non

-att

enda

nce

not e

xplo

red.

Aut

hors

ac

know

ledg

e th

at o

nly

mor

e re

cent

stu

dies

(ele

ctro

nic

rath

er th

an p

aper

rem

inde

rs) l

ikel

y to

be

rele

vant

now

.Po

tent

ial p

ublic

atio

n bi

as n

otw

ithst

andi

ng, a

utho

rs

conc

lude

tha

t m

ost

incl

uded

inte

rven

tions

mod

estly

im

prov

ed a

tten

danc

e. A

ppea

rs r

elia

ble,

but

did

not

in

vest

igat

e fa

ctor

s th

at m

ight

influ

ence

effe

ctiv

enes

s of

the

se in

terv

entio

ns in

diff

eren

t po

pula

tions

and

se

ttin

gs. D

iffer

ent

rem

inde

rs n

ot c

ompa

red

with

eac

h ot

her.

Con

clus

ion

that

tel

epho

ne r

emin

ders

wer

e be

tter

tha

n te

xt a

nd p

ost

rem

inde

rs m

ay n

ot b

e re

liabl

e. N

o fo

rmal

eva

luat

ion

of c

ost-

effe

ctiv

enes

s, so

con

clus

ion

on r

elat

ive

cost

-effe

ctiv

enes

s of

in

terv

entio

ns a

lso m

ay n

ot b

e re

liabl

e.

Tel

epho

ne, m

ail,

and

text

/SM

S in

terv

entio

ns a

ll im

prov

ed a

tten

danc

e m

odes

tly b

ut a

t va

ryin

g co

sts.

T

ext

mes

sagi

ng m

ost

cost

-effe

ctiv

e of

the

thr

ee, b

ut

its a

pplic

abili

ty m

ay b

e lim

ited.

Few

dat

a av

aila

ble

rega

rdin

g el

ectr

onic

mai

l rem

inde

rs, w

here

as o

pen-

acce

ss s

ched

ulin

g is

are

a of

act

ive

rese

arch

.

Not

e: w

e ac

know

ledg

e th

e as

sist

ance

of t

he C

entr

e fo

r R

evie

ws

and

Dis

sem

inat

ion

in p

rovi

ding

qua

lity

asse

ssm

ents

for

incl

uded

rev

iew

s, in

clud

ing

the

Stub

bs e

t al

41 r

evie

w w

hich

was

pro

vide

d on

dem

and.

Abb

revi

atio

ns: R

CT

, ran

dom

ized

con

trol

led

tria

l; R

R, r

elat

ive

risk

; CI,

confi

denc

e in

terv

al; C

RD

, Cen

tre

for

Rev

iew

s an

d D

isse

min

atio

n; S

MS,

sho

rt m

essa

ge s

ervi

ce; D

AR

E, D

atab

ase

of A

bstr

acts

of R

evie

ws

of E

ffect

s; D

NA

, did

not

att

end;

N

HS,

UK

Nat

iona

l Hea

lth S

ervi

ce.

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487

effectiveness and optimization of appointment reminders

Tab

le 3

Rem

inde

r te

chno

logi

es a

sses

sed

and

outc

omes

rep

orte

d by

eac

h R

CT

Stud

ySt

udy

char

acte

rist

ics

Lett

erP

erso

naliz

ed

tele

phon

e ca

llA

utom

ated

te

leph

one

Mob

ile/

SMS

Voi

ce

mes

sagi

ngE

mai

lO

ther

Com

para

tor

Att

enda

nce

outc

omes

Ove

rall

effe

ct

Bos

et a

l42th

e N

ethe

rlan

ds,

orth

odon

tic c

linic

, (N

=301

)

N

o re

min

der

Stan

dard

ized

failu

re r

ate;

re

spon

dent

s’ a

ttitu

des

to r

ecei

ving

rem

inde

r;

resp

onde

nts’

rem

inde

r pr

efer

ence

s

Non

-att

enda

nce

rate

red

uced

by

4.5

%

Can

et

al43

UK

, ort

hodo

ntic

clin

ic,

(N=2

31)

i

No

rem

inde

rA

tten

danc

e ra

tes

Non

-att

enda

nce

rate

red

uced

by

4.2

%C

hen

et a

l44Pe

ople

’s R

epub

lic o

f C

hina

, hea

lth p

rom

otio

n ce

nter

, (N

=1,8

59)

No

rem

inde

rA

tten

danc

e ra

tes;

cos

t pe

r at

tend

ance

of i

nter

vent

ion

Non

-att

enda

nce

rate

red

uced

by

7%

Chi

u45H

ong

Kon

g, r

adio

logy

ou

tpat

ient

s, (

N=3

11)

No

rem

inde

rA

tten

danc

e ra

tes

Non

-att

enda

nce

rate

red

uced

by

9.4

%C

ho e

t al

46K

orea

, hos

pita

l-ba

sed

fam

ily p

ract

ice

outp

atie

nts,

(N

=918

)

No

rem

inde

rA

tten

danc

e ra

tes;

cos

t pe

r at

tend

ance

Non

-att

enda

nce

rate

red

uced

by

3.4

% (

SMS)

and

by

1.1%

(t

elep

hone

cal

l)C

hris

tens

en

et a

l47

USA

, chi

ldre

n’s

dent

al

clin

ic, (

N=3

13)

ii

No

rem

inde

rPu

nctu

ality

for

appo

intm

ent

(15

min

utes

); ra

te o

f mis

sed

appo

intm

ents

Non

-att

enda

nce

rate

red

uced

by

21%

(48

hou

rs)

and

by 2

6%

(24

hour

s)C

omfo

rt

et a

l48

USA

, sub

stan

ce a

buse

cl

inic

, (N

=102

)

No

enga

gem

ent

enga

gem

ent

with

ser

vice

sN

o st

atis

tical

ly s

igni

fican

t di

ffere

nces

Cos

ta e

t al

,49

Cos

ta e

t al

50

Port

ugal

, out

patie

nts

clin

ics,

(N

=3,3

62)

N

o re

min

der

Non

-att

enda

nce

rate

Non

-att

enda

nce

rate

red

uced

by

3.5

%Fa

irhu

rst

and

Shei

kh51

UK

, inn

er-c

ity g

ener

al

prac

tice,

(N

=418

)

No

rem

inde

rN

on-a

tten

danc

e ra

tes

Non

-att

enda

nce

rate

red

uced

by

5.3

%G

olde

nber

g et

al52

USA

, tea

chin

g cl

inic

, (N

=723

)

iiiN

o re

min

der

Att

enda

nce

(sho

w)

rate

sN

on-a

tten

danc

e ra

te r

educ

ed

by 1

0%G

riffi

n

et a

l53

USA

, col

posc

opy

clin

ic,

(N=1

,876

)

iv

No

rem

inde

rA

ppoi

ntm

ent

non-

atte

ndan

ce; p

atie

nt

perc

eptio

ns a

bout

the

cal

l

38%

, 42%

, and

41%

did

not

at

tend

in iv

R7,

ivR

3, a

nd N

DC

ar

ms,

res

pect

ivel

y; 3

3% (

FS)

and

38%

(co

lono

scop

y) n

on-

atte

ndan

ce a

t ba

selin

eH

ashi

m

et a

l54

USA

, urb

an fa

mily

pr

actic

e, (

N=9

30)

N

o re

min

der

Out

com

e of

cal

l (c

onfir

med

, una

ble

to le

ave

mes

sage

, app

oint

men

t ca

ncel

led

by p

atie

nt/fa

mily

, ap

poin

tmen

t re

-sch

edul

ed

by p

atie

nt/fa

mily

, or

no

activ

e te

leph

one

num

ber)

; co

st o

f rem

inde

rs

Non

-att

enda

nce

rate

red

uced

by

6.9

% (

95%

Ci,

1.5%

–12%

)

(Con

tinue

d)

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488

McLean et al

Tab

le 3

(Co

ntin

ued)

Stud

ySt

udy

char

acte

rist

ics

Lett

erP

erso

naliz

ed

tele

phon

e ca

llA

utom

ated

te

leph

one

Mob

ile/

SMS

Voi

ce

mes

sagi

ngE

mai

lO

ther

Com

para

tor

Att

enda

nce

outc

omes

Ove

rall

effe

ct

irig

oyen

et

al55

USA

, ped

iatr

ic

vacc

inat

ion

clin

ic,

(N=1

,273

)

v

N

o re

min

der

App

oint

men

t ra

tes;

va

ccin

atio

n co

vera

ge; c

ost

of r

emin

ders

Non

-att

enda

nce

rate

red

uced

by

6.7

%

Kitc

hem

an

et a

l56

UK

, inn

er-c

ity

outp

atie

nts,

(N

=764

)

No

rem

inde

rA

tten

danc

e at

firs

t ap

poin

tmen

t; co

ntin

uing

at

tend

ance

; hos

pita

lizat

ion,

tr

ansf

er o

f car

e, d

isch

arge

, pr

esen

tatio

n at

acc

iden

t an

d em

erge

ncy

and

deat

h by

1 y

ear

Non

-att

enda

nce

rate

red

uced

by

6.5

%

Kou

ry a

nd

Fari

s57

UK

, ear

, nos

e an

d th

roat

clin

ics;

(N

=291

)

N

o re

min

der

Non

-att

enda

nce

rate

; w

illin

gnes

s to

rec

eive

SM

SN

on-a

tten

danc

e ra

te r

educ

ed

by 8

%K

won

et

al58

USA

, ele

ctro

diag

nost

ic

labo

rato

ry; (

N=4

04)

N

o re

min

der

Non

-att

enda

nce

with

out

prio

r no

tifica

tion

Non

-att

enda

nce

redu

ced

by

2.6%

but

not

sig

nific

antly

. Fo

r ap

poin

tmen

ts o

f par

ticul

ar

test

eg,

ele

ctro

myo

grap

hy,

non-

atte

ndan

ce r

ate

redu

ced

by 2

1.7%

Leon

g et

al59

Mal

aysi

a, p

rim

ary

care

cl

inic

s, (

N=9

93)

No

rem

inde

rA

tten

danc

e ra

tes;

cos

ts o

f in

terv

entio

nsN

on-a

tten

danc

e ra

te r

educ

ed

by 1

0.9%

(SM

S); n

on-a

tten

danc

e ra

te r

educ

ed b

y 11

.5%

(m

obile

); co

st o

f SM

S re

min

der

low

er

than

mob

ile p

hone

rem

inde

rLi

ew e

t al

60M

alay

sia,

pri

mar

y ca

re

clin

ics,

(N

=931

)

N

o re

min

der

Non

-att

enda

nce

rate

sN

on-a

tten

danc

e ra

te r

educ

ed

by 9

.3%

(te

leph

one

call)

; non

-at

tend

ance

rat

e re

duce

d by

7.

4% (

SMS)

Max

wel

l et

al61

USA

, inn

er-c

ity c

linic

s,

(N=2

,304

)

N

o re

min

der

App

oint

men

t ad

here

nce

rate

sN

on-a

tten

danc

e ra

te r

educ

ed

by 3

.2%

(m

aile

r). N

on-

atte

ndan

ce r

ate

redu

ced

by

2.1%

(te

leph

one

call)

Nel

son

et

al62

USA

, ped

iatr

ic d

enta

l cl

inic

s, (

N=3

18)

S

MS

Mob

ileA

tten

danc

e ra

tes

8.97

% im

prov

emen

t in

voi

ce

over

tex

tO

ladi

po

et a

l63

UK

, col

posc

opy

clin

ic,

(N=1

89)

N

o re

min

der

Att

enda

nce

rate

Non

-att

enda

nce

rate

red

uced

by

22%

Pari

kh

et a

l64

USA

, aca

dem

ic

outp

atie

nt c

linic

s,

(N=9

,835

)

No

rem

inde

rN

on-a

tten

danc

e ra

te;

canc

ella

tion

rate

; pat

ient

sa

tisfa

ctio

n

Non

-att

enda

nce

rate

red

uced

by

9.5

% (

pers

onal

ized

); no

n-at

tend

ance

rat

e re

duce

d by

5.

8% (

auto

mat

ed)

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489

effectiveness and optimization of appointment reminders

Perr

on

et a

l65

Switz

erla

nd, H

iv/

prim

ary

care

clin

ics,

(N

=2,1

23)

N

o re

min

der

Rat

e of

mis

sed

appo

intm

ents

, cos

t of

in

terv

entio

n, a

nd p

rofil

e of

pat

ient

s m

issi

ng t

heir

ap

poin

tmen

ts

Non

-att

enda

nce

rate

red

uced

by

3.6

%

Pras

ad a

nd

Ana

nd66

indi

a, d

enta

l pre

vent

ive

care

, (N

=206

)

No

rem

inde

rA

tten

danc

e ra

teN

on-a

tten

danc

e ra

te r

educ

ed

by 4

3.7%

Ret

i67N

ew Z

eala

nd, h

ospi

tal

outp

atie

nts

depa

rtm

ent,

(N=1

09)

vi

No

rem

inde

rN

on-a

tten

danc

e ra

tes

Non

-att

enda

nce

rate

red

uced

by

22%

Ritc

hie

et

al68

Aus

tral

ia, h

ospi

tal

outp

atie

nts

depa

rtm

ent,

(N=4

00)

N

o re

min

der

Mak

ing

the

reco

mm

ende

d ap

poin

tmen

t; at

tend

ance

at

sche

dule

d ap

poin

tmen

t; an

d re

ason

s fo

r no

n-at

tend

ance

at

sch

edul

ed a

ppoi

ntm

ent

Non

-att

enda

nce

rate

red

uced

by

16.

2%

Rob

erts

and

Pa

rtri

dge69

UK

, res

pira

tory

clin

ics,

(N

=504

)

Usu

al c

are

Att

enda

nce

rate

; cos

t of

in

terv

entio

nN

on-a

tten

danc

e ra

te r

educ

ed

by 1

5% c

ompa

red

with

con

trol

(7

1%, n

=258

) an

d w

ith p

atie

nts

who

cou

ld n

ot b

e co

ntac

ted

(68%

, n=1

42)

(P=0

.007

; P=0

.004

)R

utla

nd

et a

l70

UK

, gen

itour

inar

y m

edic

ine

clin

ic, (

N=2

52)

SM

S pl

us h

ealth

pr

omot

ion

mes

sage

and

no

rem

inde

r

Re-

atte

ndan

ce r

ates

Non

-re-

atte

ndan

ce r

ate

redu

ced

by 3

.7%

for

text

rem

inde

r on

ly.

Non

-re-

atte

ndan

ce r

ate

redu

ced

by 1

0.7%

whe

n re

min

der

acco

mpa

nied

by

heal

th

prom

otio

nal m

essa

geSa

wye

r

et a

l71

Aus

tral

ia, a

dole

scen

t cl

inic

s (N

=53)

No

rem

inde

rC

linic

non

-att

enda

nce,

reas

on fo

r no

n-at

tend

ance

, an

d sa

tisfa

ctio

n w

ith t

he

book

ing

syst

em

Non

-att

enda

nce

rate

red

uced

by

12%

Tay

lor

et a

l4A

ustr

alia

, phy

sica

l th

erap

y cl

inic

, (N

=679

)

No

rem

inde

rR

ate

of n

on-a

tten

danc

e w

ithou

t ca

ncel

latio

n;

canc

ella

tion

and

atte

ndan

ce

rate

s; fa

ctor

s as

soci

ated

w

ith n

on-a

tten

danc

e

Non

-att

enda

nce

rate

red

uced

by

5%

Tom

linso

n et

al72

UK

, col

posc

opy

clin

ic,

(N=5

00)

vi

iSt

anda

rd

info

rmat

ion

– no

rem

inde

r

Att

enda

nce

and

defa

ult

rate

sN

on-a

tten

danc

e ra

te r

educ

ed

by 1

7%

Not

es: i P

lus

repl

y sl

ip; ii te

leph

one

call

at 2

4 ho

urs

and

48 h

ours

pri

or to

app

oint

men

t; iiite

leph

one

call

(doc

tor)

and

tele

phon

e ca

ll (s

ecre

tary

); ivin

tera

ctiv

e vo

ice

resp

onse

at 3

and

7 d

ays

prio

r to

app

oint

men

t, v p

ostc

ard

and

post

card

/tel

epho

ne

call;

vite

leph

one

call

from

hos

pita

l and

tel

epho

ne c

all f

rom

doc

tor;

vii p

osta

l rem

inde

r an

d le

aflet

.A

bbre

viat

ions

: N, n

umbe

r of

par

ticip

ants

in s

tudy

; RC

T, r

ando

miz

ed c

ontr

olle

d tr

ial;

SMS,

sho

rt m

essa

ge s

ervi

ce; C

I, co

nfide

nce

inte

rval

; IV

R, i

nter

activ

e vo

ice

resp

onse

; FS,

flex

ible

sig

moi

dosc

opy;

ND

C, N

urse

-del

iver

ed c

alls

.

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490

McLean et al

the included RCTs examined either automated telephone

reminders (15/31) or SMS texting services (12/31). Seven

RCTs examined personalized telephone calls and 9/31 studies

examined postal (letter/postcard) reminders. In most studies

the comparator was no intervention. The principal func-

tions of the various reminder systems were reminder only,

reminder requiring confirmation, reminder plus orientation

or reminder plus supporting clinical information. A variety of

attendance related outcomes were measured. These included

attendance, cancellation, rescheduling, and patient satisfac-

tion. A judgement of the quality of the uniquely identified

RCTs is shown in Table 4.

Reminders increase attendance at appointmentsThere was consistent evidence that reminder systems improve

appointment attendance across a range of health care settings

and patient population sub-groups. Only one of the 31 RCTs

did not show a significant reduction in non-attendance.48

“Simple reminders”, which provide details of date, time, and

location of appointments, were most frequently investigated.

“Reminder plus”, which provides additional information

(eg, orientation information, health information, etc) over

and above date, time, and location of the appointment, was

less commonly investigated. Both were effective at reducing

non-attendance.

There was consistent, strong evidence from SRs16,34,35,37,41

and RCTs32,65 that simple reminders are effective at increasing

attendance at appointments compared with no reminder. In

SRs, the pooled effects of simple reminders on appointment

attendance vs no reminder indicated significant increases in

attendance, with relative risks ranging between 1.06–1.10.34,35

One SR reported a weighted mean relative change of 34%

from the baseline non-attendance rate.37 In RCTs the differ-

ence in attendance between subjects who received remind-

ers and those who did not ranged from 5% in an Australian

physiotherapy clinic to 44% in an Indian dental preventive

care clinic.4,66 There was strong evidence from SRs16,34,35 and

RCTs42,65 that there is no differential effectiveness between

different reminder technologies, eg, SMS reminders, phone

call reminders or other reminders.

There was weak, but consistent evidence from five studies

that “Reminder plus” is more effective than simple remind-

ers at reducing non-attendance. Examples of “Reminder

plus” interventions include SMS notification of appointment

with a health promotional message or postal reminders

with additional information about medical procedures and

the importance of follow-up.70,72 A Cochrane Review40 of Tab

le 4

Judg

emen

t on

qua

lity

of in

clud

ed t

rial

s (n

ot a

lrea

dy c

over

ed in

incl

uded

rev

iew

s)

Stud

yR

evie

w q

uest

ion/

aim

sO

vera

ll re

view

qua

lity

Impl

icat

ions

for

tech

nolo

gies

Impl

icat

ions

for

spec

ific

popu

lati

ons

Com

fort

et

al48

To

exam

ine

the

effe

ct o

f the

pro

visi

on o

f “t

angi

ble”

eng

agem

ent

serv

ices

dur

ing

the

inta

ke p

erio

d to

wom

en’s

out

patie

nt s

ubst

ance

ab

use

trea

tmen

t on

rat

es o

f adm

issi

on,

rete

ntio

n, a

nd s

ervi

ce u

tiliz

atio

n.T

he e

ngag

emen

t gr

oup

rece

ived

add

ition

al

serv

ices

suc

h as

tra

nspo

rt a

nd c

hild

car

e to

hel

p w

ith t

he u

ptak

e an

d su

stai

nabi

lity

of s

ervi

ce u

se.

Poor

qua

lity

of r

epor

ting

of t

he

stud

y de

sign

mak

es it

diffi

cult

to

judg

e qu

ality

. No

repo

rtin

g of

bl

indi

ng, a

lloca

tion

to g

roup

s, fo

llow

-up

of a

ll pa

rtic

ipan

ts. T

he s

ampl

e si

ze w

as v

ery

smal

l, w

hich

may

hav

e le

d to

the

lack

of s

igni

fican

t re

sult.

Nil

Thi

s w

as a

stu

dy a

bout

wom

en r

ecei

ving

ou

tpat

ient

sub

stan

ce a

buse

pro

gram

s, b

ut

did

not

prod

uce

any

sign

ifica

nt fi

ndin

gs.

Cos

ta e

t al

,49

Cos

ta e

t al

50

Red

uce

rate

s of

FT

A b

y se

ndin

g SM

S 2

days

be

fore

app

oint

men

t. Se

nt b

y iT

dep

artm

ent.

Pers

onal

ized

to

exte

nt t

hey

incl

uded

: nam

e of

in

stitu

tion,

pat

ient

nam

e, t

ype

of a

ppoi

ntm

ent,

date

and

tim

e. w

hen

nece

ssar

y, in

clud

ed a

dvic

e to

arr

ive

earl

ier.

Lack

of r

epor

ting

on a

lloca

tion

to

inte

rven

tion

grou

ps, b

lindi

ng o

f pa

rtic

ipan

ts, a

nd la

ck o

f rep

ortin

g on

fo

llow

-up

of a

ll pa

rtic

ipan

ts. S

ampl

e si

ze c

alcu

latio

ns u

nder

take

n. S

eem

s re

ason

ably

rob

ust

stud

y, b

ut n

ot

wel

l rep

orte

d.

SMS

impr

oves

att

enda

nce

rate

s co

mpa

red

with

no

rem

inde

r.R

ates

of n

on-a

tten

danc

e hi

ghes

t in

yo

unge

r ag

e gr

oups

(un

der

15, a

nd

decr

ease

s w

ith a

ge);

in m

ales

; peo

ple

atte

ndin

g fo

r th

e fir

st t

ime;

peo

ple

atte

ndin

g fo

r te

sts;

high

est

on w

edne

sday

s; hi

gher

in t

he m

orni

ng; v

arie

s by

mob

ile

phon

e ne

twor

k; a

nd is

hig

her

for

med

ical

th

an s

urgi

cal s

peci

altie

s, bu

t ev

en h

ighe

r in

“ot

hers

” (a

nd s

peci

alty

is t

he m

ost

sign

ifica

nt d

iffer

ence

). A

ll P,

0.5.

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491

effectiveness and optimization of appointment reminders

Gol

denb

erg

et a

l52

impr

ove

adhe

renc

e to

new

pat

ient

app

oint

men

ts;

asse

ss e

ffect

iven

ess

of te

leph

one

rem

inde

rs o

n co

mpl

ianc

e; to

iden

tify

othe

r fa

ctor

s af

fect

ing

patie

nt a

dher

ence

to a

ppoi

ntm

ents

.

Con

fere

nce

abst

ract

onl

y, s

o la

cks

deta

il, R

CT,

sam

ple

size

393,

inte

ntio

n to

trea

t use

d. U

nabl

e to

com

men

t on

blin

ding

or

proc

ess

of r

ando

miz

atio

n.

Dir

ect

pers

onal

con

tact

with

pat

ient

incr

ease

s lik

elih

ood

of a

tten

danc

e.Pr

ivat

ely

insu

red

patie

nts

mor

e lik

ely

to

atte

nd t

han

Med

icai

d pa

tient

s (6

1% v

s 46

%).

Mor

e de

priv

ed c

omm

uniti

es le

ss

likel

y to

att

end.

Pras

ad a

nd

Ana

nd66

To

eval

uate

the

effi

cacy

of a

ppoi

ntm

ent

rem

inde

rs, s

ent

as S

MS

text

mes

sage

s to

pa

tient

s’ m

obile

tel

epho

nes,

in c

ompa

riso

n w

ith

no r

emin

ders

giv

en t

o pa

tient

s, a

t ou

tpat

ient

cl

inic

s at

the

iTS

Cen

tre

for

Den

tal S

tudi

es a

nd

Res

earc

h, M

urad

naga

r, G

hazi

abad

, Utt

arPr

ades

h, in

dia.

Ran

dom

ized

at

depa

rtm

enta

l, ra

ther

th

an p

atie

nt le

vel,

so d

iffer

ence

s m

ay b

e du

e to

diff

eren

t tr

eatm

ent

type

/pat

ient

gro

ups.

No

blin

ding

, no

inte

nt t

o tr

eat

anal

ysis

pro

vide

d.

SMS

may

impr

ove

atte

ndan

ce r

ate

in c

ompa

riso

n w

ith n

o re

min

der

(alth

ough

evi

denc

e w

eak)

.w

hen

appo

intm

ent

rem

inde

rs w

ere

bein

g sc

hedu

led,

22

patie

nts

stat

ed t

hat

they

di

d no

t un

ders

tand

the

eng

lish

lang

uage

. R

emin

ders

for

thes

e su

bjec

ts w

ere

sent

in

the

loca

l lan

guag

e on

the

mob

ile p

hone

. in

add

ition

, a p

ictu

re m

essa

ge o

f the

in

stitu

tion

was

sen

t to

sev

en p

atie

nts.

Tay

lor

et a

l4T

o de

term

ine

whe

ther

SM

S re

duce

s ra

tes

of

non-

atte

ndan

ce in

phy

siot

hera

py o

utpa

tient

ap

poin

tmen

ts. S

econ

dary

aim

s w

ere

to e

valu

ate

effe

ct o

f SM

S re

min

ders

on

canc

ella

tion

and

atte

ndan

ce r

ates

and

exp

lore

fact

ors

asso

ciat

ed

with

non

-att

enda

nce.

Goo

d qu

ality

, wel

l pow

ered

, wel

l co

nduc

ted

RC

T.

Stro

ng e

vide

nce

to s

how

tha

t pe

ople

who

wer

e no

t se

nt a

n SM

S w

ere

1.77

tim

es m

ore

likel

y no

t to

att

end

thei

r ap

poin

tmen

t (in

clud

es a

djus

ting

for

othe

r fa

ctor

s).

Oth

er s

tatis

tical

ly s

igni

fican

t co

ntri

buto

rs t

o th

e m

odel

wer

e he

alth

co

nditi

on/d

iagn

osis

of n

eck

and

trun

k m

uscu

losk

elet

al d

isor

der

(OR

, 2.8

6; 9

5%

Ci,

1.53

–5.3

2), n

euro

mus

cula

r di

sord

er

(OR

, 3.2

7; 9

5% C

i, 1.

17–9

.17)

, and

age

(O

R, 0

.98;

95%

Ci,

0.97

–0.9

95).

Gri

ffin

et a

l53T

o te

st w

heth

er a

n in

tera

ctiv

e vo

ice

resp

onse

(iv

R)

syst

em p

hone

cal

l was

equ

ally

effe

ctiv

e as

nur

se-d

eliv

ered

pho

ne c

all a

t ed

ucat

ing

and

prep

arin

g pa

tient

s fo

r fle

xibl

e si

gmoi

dosc

opy

(FS)

and

col

onos

copy

exa

min

atio

ns. O

utco

mes

w

ere

appo

intm

ent

non-

atte

ndan

ce a

nd

prep

arat

ion

non-

adhe

renc

e.N

on-a

tten

danc

e de

fined

as

canc

ellin

g ap

poin

tmen

t or

not

att

endi

ng a

ppoi

ntm

ent.

App

oint

men

ts c

ance

lled

by c

linic

not

con

side

red

as n

on-a

tten

danc

e. P

repa

ratio

n no

n-ad

here

nce

asse

ssed

whe

ther

pat

ient

s ha

d ad

equa

tely

pr

epar

ed t

o co

mpl

ete

proc

edur

e.

wel

l-con

stru

cted

stu

dy w

ith s

ampl

e si

ze c

alcu

latio

n an

d in

tent

to

trea

t, ra

ndom

izat

ion

not

spec

ified

.

Thr

ee a

rm R

CT;

nur

se p

hone

cal

l 7 d

ays

befo

re

proc

edur

e, iv

R s

yste

m c

all 7

day

s be

fore

pr

oced

ure,

and

ivR

sys

tem

cal

l 3 d

ays

befo

re

proc

edur

e. A

ll ca

lls in

clud

ed a

n ap

poin

tmen

t re

min

der,

info

rmat

ion

abou

t pr

epar

atio

n fo

r ex

amin

atio

n, a

nd e

ncou

rage

men

t to

pre

pare

fo

r an

d at

tend

the

exa

min

atio

n. iv

R s

yste

m

was

effe

ctiv

e at

rem

indi

ng p

atie

nts

of t

heir

ap

poin

tmen

ts. i

vR

sys

tem

can

effe

ctiv

ely

deliv

er c

ompl

ex in

form

atio

n, e

g, pr

epar

atio

n in

form

atio

n; e

qual

ly e

ffect

ivel

y as

pho

ne c

alls

fr

om c

linic

nur

ses

at d

eliv

erin

g in

form

atio

n;

patie

nts

rece

ivin

g iv

R m

essa

ges

repo

rted

mor

e “n

eutr

al”

perc

eptio

ns a

bout

pho

ne c

alls

; pat

ient

s re

ceiv

ing

calls

from

nur

ses

repo

rted

mor

e “v

ery

posi

tive”

per

cept

ions

abo

ut p

hone

cal

ls.

Nil

Rut

land

et

al70

To

dete

rmin

e w

heth

er S

MS

follo

w-u

p of

pa

tient

s w

ho D

NA

boo

ked

GU

M a

ppoi

ntm

ents

im

prov

es s

ubse

quen

t re

-att

enda

nce

rate

s an

d to

ass

ess

the

impa

ct o

f inc

lusi

on o

f a h

ealth

pr

omot

iona

l mes

sage

on

re-a

tten

danc

e ra

tes.

Con

fere

nce

abst

ract

onl

y, s

o la

cks

deta

il, R

CT

, sam

ple

size

252

, una

ble

to c

omm

ent

on b

lindi

ng, p

roce

ss o

f ra

ndom

izat

ion

or in

tent

ion

to t

reat

an

alys

is.

SMS

mes

sage

to c

linic

def

aulte

rs im

prov

es r

e-at

tend

ance

rat

es c

ompa

red

with

no

rem

inde

r. A

n SM

S re

min

der

with

the

addi

tion

of a

hea

lth

prom

otio

nal m

essa

ge S

MS

follo

w-u

p of

clin

ic

defa

ulte

rs im

prov

es s

ubse

quen

t re-

atte

ndan

ce r

ates

co

mpa

red

with

a r

emin

der

alone

. The

add

ition

of

a he

alth

prom

otio

nal m

essa

ge to

cur

rent

rou

tine

clin

ic r

emin

der

text

s m

ay r

educ

e D

NA

rat

es a

nd

war

rant

s fu

rthe

r st

udy

(alth

ough

evi

denc

e w

eak)

.

Patie

nts

with

a G

UM

hea

lth p

robl

em

did

not

re-a

tten

d a

clin

ical

app

oint

men

t, un

less

a r

emin

der

was

sen

t. R

emin

ders

an

d re

min

ders

with

an

addi

tiona

l hea

lth

prom

otio

nal m

essa

ge m

ay in

crea

se

the

likel

ihoo

d of

pat

ient

s w

ith a

GU

M

heal

th p

robl

em r

e-at

tend

ing

a cl

inic

al

appo

intm

ent.

(Con

tinue

d)

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492

McLean et al

Tab

le 4

(Co

ntin

ued)

Stud

yR

evie

w q

uest

ion/

aim

sO

vera

ll re

view

qua

lity

Impl

icat

ions

for

tech

nolo

gies

Impl

icat

ions

for

spec

ific

popu

lati

ons

Kw

on e

t al

58T

o m

easu

re t

he e

ffect

of t

elep

hone

rem

inde

rs

on e

lect

rodi

agno

stic

labo

rato

ry a

tten

danc

e.

elec

trod

iagn

ostic

labo

rato

ry b

ooki

ngs

of

patie

nts

wer

e ra

ndom

ly a

ssig

ned

to e

ither

a

tele

phon

e re

min

der

1 da

y pr

ior

to t

heir

ap

poin

tmen

t, or

a r

outin

e bo

okin

g (n

o re

min

der)

. Non

-att

enda

nce

was

the

pri

mar

y ou

tcom

e m

easu

re, d

efine

d as

non

-att

enda

nce

with

out

prio

r no

tifica

tion.

Con

fere

nce

abst

ract

onl

y, s

o la

cks

deta

il, R

CT

, sam

ple

size

404

, una

ble

to c

omm

ent

on b

lindi

ng, p

roce

ss o

f ra

ndom

izat

ion

or in

tent

ion

to t

reat

an

alys

is.

Tel

epho

ne r

emin

ders

red

uced

non

-att

enda

nce

at a

ll ap

poin

tmen

ts b

y 2.

6% b

ut n

ot s

igni

fican

tly.

For

appo

intm

ents

of p

artic

ular

tes

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effectiveness and optimization of appointment reminders

the effects of reminders on clinic attendance for those with

suspected serious mental illness, identified one small study

favoring a letter with an orientation statement (ie, a short

paragraph, taking about 30 seconds to read, explaining

the program of care, the fee system, and providing gentle

encouragement) over a simple letter prompting attendance.73

A second SR to assess the effect of reminder systems on

non-attendance rates at new outpatient appointments, found

limited evidence in three studies, that “Reminder plus” was

more effective than simple reminders.38 In these studies, the

reminders threatened sanctions for non-attendance, offered

rewards for attendance or provided orientation information

about the clinic.

Reminders promote cancellation/reallocation of appointmentsThere is evidence from three RCTs that personal phone

reminders significantly increase patient cancellation and

rescheduling rates.54,64,67 Patients who received a telephone

reminder were more likely to cancel or reschedule their

appointment (17%–26%) compared with a control group

who had received no reminder (8%–12%).54,67,74 Clinics

were then able to re-allocate between 27% to 40% of the

cancelled appointment slots.54,65,74 Telephone reminders

carry the inherent advantage that patients who are unable

to attend can cancel and/or reschedule their appointment at

the time of their contact with staff.67 We also found strong

evidence that SMS reminders do not increase appointment

cancellation or rescheduling,75–77 however this may be

because SMS reminders are not conventionally deployed

with this in mind.

Reminder systems are not optimally employedOur review found sufficient strong consistent evidence

to indicate that the performance of reminders, and there-

fore appointment systems, is suboptimal. Six key areas

which lead to sub-optimal reminder effectiveness were

identified.

Accuracy of patient recordsPatient contact details are frequently incorrect or out-of-

date.78,79 The likelihood of inaccurate patient records corre-

sponds with populations at greater risk of non-attendance,80

including less geographically stable communities such as

students, young adults or socio-economically deprived

groups who may frequently change address or telephone

numbers.81

Reminders may not be receivedSuccessful contact rates for telephone reminders are low

ranging from 30% to 60% in most health care settings.

Reasons for non-receipt of telephone reminders are that land-

line calls are often made during business hours (9 am–5 pm),

during the working week (Monday to Friday), when it is

likely that patients will be out.82 In addition, non-receipt may

occur because patients do not have a telephone, they do not

answer the telephone or the contact number was incorrect.74,83

Most telephone reminder systems do not leave messages for

reasons of confidentiality.

SMS reminders are reported to have successful contact

rates of 97%–99%.79,84 Successful contact is assumed when

the mobile phone indicates “message sent” being received

by the sender.44,59,66 However, many patients may either not

receive their SMS reminder or may receive and ignore a

reminder that was not intended for them due to incorrect data

entry on hospital systems.77,79 Some clients may not receive

their text message until after their scheduled appointment

because of delays in delivery of the text or because their

phones were switched off, out of battery or out of credit.85

One disadvantage of using SMS reminders alone is the dif-

ferent levels of access to a mobile telephone. Mobile phone

ownership declines sharply with increasing age,86,87 although

the total numbers of older people with mobile phone are

increasing annually.

Understanding the reminderCognitive ability, literacy level, and language determine

patient comprehension of reminders, irrespective of format.

These are important considerations for health services serv-

ing older populations, travelling communities, inner-city

deprived populations, and multilingual communities. The

studies included in our review did not explore these factors.

Two RCTs explicitly excluded patients who did not speak

the official language (English) fluently, those with dementia,

or with significant cognitive impairment.68,88 Only one RCT

used multilingual research assistants to make the reminder

phone call.65 Reminder systems can cater for different

languages.41,66

Timing of remindersWe found strong evidence that the timing of reminders,

between 1 and 7 days prior to the scheduled appointment, has

no adverse effect on patient attendance behavior.37,89 SMS or

telephone reminders are typically sent either the day before

or on the day of the health care appointment.49,57,63 Sending

the reminder close to the appointment means that the patient

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McLean et al

may either not have time to act on it or they may receive

the reminder after the allotted appointment time.65 Sending

reminders early allows patients to re-arrange commitments,

which may increase the likelihood of a patient attending,

cancelling or rescheduling.54,64,67

Patient does not cancel or re-schedule the appointmentThere are numerous reasons why patients fail to either

cancel or reschedule their appointment. Simple reminders

rarely ask patients to cancel appointments, particularly SMS

reminders where space for text is limited.46,62 Some SMS

reminders ask patients to call a telephone number rather

than replying to the text.4,57 Patients frequently encounter

problems accessing health care systems which can thwart

their intention to cancel and rebook.86,90 Problems include

difficulties accessing central booking lines, including the

phone being engaged, having to wait a long time to speak

to someone or the call being disconnected with no option

to wait or leave a message.91,92 In some cases, patients were

warned by others of the difficulties of accessing a central

booking line, which deterred them from making contact.86

In two studies, patients who failed to attend stated that they

had already phoned or written to cancel their appointment,

indicating difficulties with cancellation systems or internal

hospital communication prevented cancellations being passed

on to the relevant clinic.81,86

Lack of tailoring to high risk groupsThere was weak evidence that patient age has no impact on

reminder effectiveness, suggesting reminder systems can

be employed across all age groups.18 However, few studies

have investigated the differential impact of reminder systems

between population sub-groups. There was weak but consis-

tent evidence that deprivation, minority ethnicity, substance

abuse, mental health problems, and comorbidities/illness are

associated with non-attendance at appointments.93,94 There

was little evidence of tailoring of reminder systems to meet

the needs of these groups of patients.

DiscussionThis review found consistent, strong evidence that all reminder

systems are effective at reducing non-attendance at appoint-

ments across diverse service contexts and patient populations.

There is no clear indication of differential effectiveness

between different simple reminder systems. However, there

is some evidence that “Reminder plus” interventions can

be more effective than simple reminders. Our review of the

available evidence suggests that “Reminder plus” may result

in higher attendance than simple reminders for first appoint-

ments and screening appointments and that for subsequent

follow-up appointments simple reminders and “Reminder

plus” may produce comparable increases in attendance for

most patients most of the time. However, further research

employing appropriate comparative designs is needed before

firm conclusions can be drawn.

There is also strong consistent evidence that reminders

can increase patient cancellation/rebooking rates, however

the success may depend to some extent upon the nature and

the timing of the reminder. We found only three studies

investigating this area of effectiveness,54,64,67 therefore further

research exploring the effectiveness of reminder systems to

promote cancellation/rebooking and rescheduling of appoint-

ments is warranted.

Based on the findings presented in this review, the small

amount of evidence that some patients find reminders intru-

sive or confusing is outweighed by the benefits.95 The use of

reminders appears to be both acceptable and feasible across

a range of health care settings,42,65 and we therefore propose

that all patients should receive a reminder and that all health

care services operating outpatient appointment systems

should employ reminder systems.

Whilst reminder systems can increase attendance, cancel-

lation, rescheduling and reallocation of appointments, this

review identified six key factors which limit the efficiency of

both reminder and appointment systems. Reminder systems

are often employed with the objective of increasing atten-

dance rates, with limited attention given to cancellation and/or

rescheduling of appointments. Full attendance at appoint-

ments is unlikely to be achievable; therefore appointment

cancellation and rescheduling should be seen as desirable

outcomes. Appointment systems can be optimized if patients

cancel and reschedule unwanted appointments, allowing

health care services to re-allocate the cancelled appointment

to a different patient. If appointment and reminder systems

are to realize their full potential this will require a whole

systems approach to looking at the characteristics of cur-

rent systems for attendance, cancellation, rescheduling and

re-allocation of appointments to other patients. A summary

of proposed strategies is outlined in Figure 3 and discussed

in greater detail to follow.

Optimization strategiesHealth services, particularly those serving geographically

less stable communities, should have robust procedures for

maintaining and updating patient records.81

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effectiveness and optimization of appointment reminders

In many health services it will be relevant to consider the

use of both simple reminders and “Reminder plus”. Depend-

ing on the nature of the information provided, “Reminder

plus” may help patients to feel more confident about attend-

ing their appointment, particularly for first appointments and

screening appointments.56,96 Thereafter, the use of simple

reminders may be sufficient for increasing attendance at

follow-up appointments in most health care settings.

Since the timing of appointment reminders appears to

have no appreciable impact on attendance behavior when

delivered up to 7 days before an appointment, we propose

that reminders should be delivered early enough to allow

patients to re-arrange commitments so that they can attend

the appointment and receive the care that they need. Alter-

natively, if unable to attend, patients will have sufficient

time to cancel and reschedule their appointments and allow

health services to re-allocate and rebook appointments.54,64,67

To support and enhance rescheduling it is appropriate to

frame reminders to ask patients to cancel and rebook incon-

venient appointments. In addition, robust structures, which

are easy to navigate and which require minimal effort from

the patient, are required to support cancellation. Automated

methods of cancellation, eg, SMS messages or email, are

perceived by many patients as easier than methods which

require direct contact since they offer flexibility to cancel

at a time convenient to the patient and reduce the need to

provide explanations for cancellation.18,34 Following cancel-

lation of appointments, rescheduling of the appointment, if

it has not occurred synchronously, also needs to be easy for

the patient. For example it may be sensible, in some health

care settings, to have central booking lines which are open

24 hours a day.

There is little evidence of tailoring of reminder systems

to meet the needs of vulnerable groups of patients who are

at high risk of non-attendance; this includes deprived and

ethnic groups, substance abusers, and populations with co-

morbidity and illness.93,94 Given the likely coincidence of

higher levels of non-attendance and health need, it is in the

interests of health services to monitor whether specific groups

of patients are being disadvantaged by the chosen reminder

systems. Simple reminders and automated reminders may

be ignored, overlooked or misunderstood, particularly if

patients are experiencing an increase of their health prob-

lem. We therefore hypothesize that reminders with direct

personal contact might be appropriate in these groups, since

the flexibility of information, advice or support which can

be offered may help to overcome barriers to attendance or

to cancel unwanted appointments. To facilitate attendance in

these groups more intensive reminder systems are advocated.

Examples of this include sequential reminders which were

effective at improving attendance in a Swiss AIDS clinic.65

This consisted of: first, a phone call to either landline or

mobile; second, an SMS if participants do not answer the

phone after three attempts and have a mobile phone; and

finally a postal reminder if participants do not answer the

phone, have no mobile phone or landline at all. Intensive

approaches, such as “stepped reminders” and patient navi-

gators have also been effective at increasing attendance at

screening and immunization programs in disadvantaged and

vulnerable populations and might also be effective at re-

engaging similar groups of patients who have dropped out of

treatment.36,97–99 Such designs, though labor intensive would

reach the maximum number of participants and may increase

attendance rates and simultaneously have a cost benefit.

An effective reminder and cancellation system will in crease

the already heavy workload of outpatient clinics.52 Clinicians

frequently fill missed appointments with alternative activi-

ties such as completing dictation, making telephone calls or

1) Maintain accurate patient contact details (with alternative contact routes wherever possible). 2) Select reminder technologies that are suitable for the needs of the population; possibly more than one. 3) Where appropriate use "Reminder plus" technologies to overcome common barriers to attendance. 4) Send reminder a minimum of 2–3 days in advance of the appointment. 5) Frame reminders to ask patients to cancel and reschedule unwanted appointments. 6) Employ multiple systems for cancelling appointments which suit the needs of the patients, not the needs of the

service eg, automated SMS cancellation, answer-phone, email etc. 7) Have robust rescheduling procedures in place to allow easy rescheduling of appointments for patients, both within

and out of normal working hours.  8)  Monitor whether any specific groups of patients are being disadvantaged by the chosen reminder systems. 9) Employ personalized or intensive reminder strategies for groups of patients at high risk of non-attendance.10) Build in administrative time for clinicians to manage tasks which were previously routinely carried out when a

patient missed an appointment.

Figure 3 Summary of strategies to optimize reminder systems.Abbreviation: SMS, short message service.

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McLean et al

consulting with colleagues.56 If building in processes to opti-

mize cancellation and rescheduling, then health services will

need also to consider the impact on staff that frequently utilize

non-attendance at appointments as an opportunity to catch up

on other health care related activities.

Strengths and limitationsOur approach to this review, which combined an SR with

an evidence synthesis informed by realist principles, has

numerous strengths, including a structured search protocol

requiring thorough searches of electronic databases, reference

lists, and citations. As a consequence we believe that we have

assembled the widest possible body of relevant knowledge

which has relevance across all health care services which

use appointment systems. In addition, our review informed

by realist principles includes the strong embedding of our

findings in the extracted data. This stems from the practical

orientation of our review and facilitates the production of

implications for practice. There are also limitations to our

review. Generally speaking the SR method seeks to provide

a precise answer to a tightly focused question. Such reviews

are most useful where there is a high degree of homogeneity

around the five PICOS elements, namely the Population,

Intervention, Comparison, Outcomes, and Study types.

A wide range of population types, intervention, compari-

son, and outcomes is included within the RCTs we identified.

However, use of this wider approach offers greater analytical

capability in terms of understanding contextual and mecha-

nistic factors that would not have been evident in a more

narrowly focused review and increases confidence that the

findings have relevance in a wide range of service settings.

Research implicationsWe recommend future research activities in three main

areas. Firstly, more studies should routinely consider

the potential for differential effects of reminder systems

between patient groups in order to identify any inequali-

ties and remedies. Secondly, “Reminder plus” systems

appear promising but there is a need for further research

to understand how they influence attendance behavior.

Finally, further research is required to identify strategies

to “optimize” reminder systems and compare performance

against current approaches.

ConclusionIn the absence of clear contraindications all health services

should use simple reminders or “Reminder plus” for all

patients. More intensive reminder alternatives may be relevant

for key groups of patients: deprived, ethnic, substance abusers,

and those with comorbidities and illness.

There is evidence that reminders are used sub-optimally.

To optimize appointment and reminder systems, health

services should tailor reminder systems and adopt supportive

administrative processes to enhance attendance, cancel-

lation, rescheduling, and reallocation of appointments to

other patients.

AcknowledgmentsThe TURNUP project was funded by the National Insti-

tute for Health Research Health Services and Delivery

Research Program (project number 10/2002/49). The

views and opinions expressed are those of the authors and

do not necessarily reflect those of the HS&DR program,

NIHR, NHS or the Department of Health. This paper or

the abstract of this paper has been presented as a platform

presentation at the World Congress of Physical Therapy,

Singapore in May 2015 and will also be presented as a plat-

form presentation at Physiotherapy UK in October 2015,

Liverpool UK. The abstract was published in Physiotherapy

Journal: http://www.physiotherapyuk.org.uk/presentation/

appointment-reminder-systems-are-effective-not-optimal-

results-systematic-review-and. The actual paper, however,

has never been published.

DisclosureThe authors report no conflicts of interest in this work.

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