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Approaches to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

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Page 1: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

Approaches to type II

Endoleaks: Transcaval,

transarterial, translumbar

Saher Sabri ,MD

University of Virginia

Page 2: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

Saher Sabri, M.D.

• Speakers Bureau: W.L.Gore & Associates, Abbott

Page 3: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

• Type II Endoleaks

– 10-25% incidence

– Natural history unclear

• management of Type II

endoleaks is controversial

• >60% spontaneously

resolve

• Rupture is rare

Type 2 Endoleaks after EVAR

Page 4: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

• Persistent type II endoleaks are

associated with

• Increased risk of sac growth ( OR 26)

• Significant predictor of aneurysm

rupture

• No increase in aneurysm related

mortality

Jones et al JVS 2007 ;46:1-8

Page 5: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

• Type II endoleak with stable diameter

does not demonstrate higher rate of

rupture compared with stable aneurysms

without endoleak

• Van Marrewijk et al ( JVS 2002;35 :46-473)

Page 6: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

• Type II endoleaks

– Decrease sac size – No therapy

– Increase sac size – Treat

– Stable sac size – when to treat? • Persistent > 6 months ?

• Predictors of persistent endoleaks

– Numerous collaterals (>3 vessels)

– Large central nidus (>15 mm)

– High flows (velocities >100cm/s)

– Chronic anticoagulation

Endoleak Management

Page 7: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Think of complex endoleaks

like an AVM with a “Nidus”

AAA

AVM

Page 8: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Access

• Direct sac puncture

• Trans-arterial

• Trans-Caval

Page 9: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Direct sac puncture

• Fluoro guided

• Cone beam CT or Fusion software

• 22 g access needle

• Transition to 4-6 fr

• Embolize through a microcatheter ( as

needed)

Page 10: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Direct Sac Access Angiogram – Onyx Embolization

Page 11: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Pre Post

Page 12: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Pre-Onyx Post-Onyx

Page 13: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

CT Angiogram – Type II Endoleak

Aneurysm sac measures 5.3 cm

Page 14: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Complex Type II Endoleak

( Ant and Post components)

Page 15: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Direct Sac Puncture – Type II Endoleak

Conebeam CT

Sac Puncture

Page 16: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

AP Lat

Sac angiogram

shows IMA

outflow

IMA IMA

Page 17: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

IMA access via

direct sac puncture

IMA

embo

with

coils

Onyx

embo

Nidus

Page 18: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Endoleak Treatment – F/U CTA

Contrast CT Pre-Onyx Non-contrast CT Post Onyx

Page 19: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Complications

• Psoas hematoma

• Transient Lumbar nerve paresis

• Retroperitoneal Onyx/glue leak

• Complications are usually minor

without clinical sequelae

Page 20: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transarterial access

• SMA-IMA pathway

• Iliolumbar pathway

Page 21: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transarterial Embolization –SMA/IMA

Page 22: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transarterial Embolization-Lumbar outflow

Page 23: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transarterial Embolization

Page 24: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transarterial Embolization

Page 25: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transarterial Embolization

Page 26: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Type II Endoleak• 78 year old s/p EVAR 6 months ago

• Since 1 month scan Type II endoleak with 5 mm aneurysm

growth

Page 27: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 28: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 29: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

IMA Not

contributing

Page 30: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Aortic sac filling

Trans-iliolumbar access

Internal iliac angiogram

Page 31: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 32: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 33: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 34: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 35: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 36: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 37: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 38: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Prior lumbar embo

Transcaval access

Page 39: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transcaval access

Trans-septal

needle

0.018 wire

Page 40: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Microcatheter

Page 41: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 42: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 43: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Page 44: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Type II Leak Resolved—No AAA

Growth at 6 months

Page 45: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Transcaval Endoleak Embolization• 29 embolizations in 26 patients for type II endoleaks with

aneurysm growth

• Mean of 4.2 ± 4 years after EVAR

• 46% had prior procedures (5 translumbar, 3 transarterial, 3 transcaval, 1 aortic cuff, and 1 iliac limb extension)

• 2 had no flow identified in the aneurysm sac (1 had a hygromarather than arterial flow)

• 83% success in getting transcaval access to aorta

• Mean fluoroscopy time was 27 ± 13 minutes with 29 ± 21 mL of contrast – median of 10 coils per case

– thrombin injection (17%)

• No procedural adverse events

• One-year freedom from reintervention 95%

Giles KA, et al. Results of transcaval embolization for sac expansion

from type II endoleaks after endovascular aneurysm repair. J Vasc

Surg. 2015 May;61(5):1129-36.

Page 46: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Suggested algorithm for Type II

• IMA patent : Transarterial SMA-IMA

access

• IMA occluded : Transarterial iliolumbar

access Or Direct sac puncture

• Personal preference: start with iliolumbar

access and reserve direct sac for failed

iliolumbar access ( diminutive iliolumbar

arterial pathway) or residual endoleak

• Transcaval for right sided endoleaks

Page 47: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Peri-iliac-graft access

Page 48: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Peri-iliac-graft access

Wedge a 5 fr catheter between the iliac wall and

the graft and access the sac with a microcatheter

even in the absence of type 1 b endoleak

Page 49: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Q #1 Which of the following

about type II endoleak is true

• A. Persistent endoleak with no sac diameter

enlargement leads to higher incidence of rupture

• B. Type II endoleaks are associated with higher

aneurysm related mortality

• C. Type II endoleaks persistent beyond 6 months are

predictors of increase in sac diameter

• D. Type II endoleak post TEVAR have similar incidence

to type II endoleaks post EVAR

Page 50: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Q #1 Which of the following

about type II endoleak is true

• A. Persistent endoleak with no sac diameter

enlargement leads to higher incidence of rupture

• B. Type II endoleaks are associated with higher

aneurysm related mortality

• C. Type II endoleaks persistent beyond 6 months are

predictors of increase in sac diameter ( correct answer)

• D. Type II endoleak post TEVAR have similar incidence

to type II endoleaks post EVAR

Page 51: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Q # 2 Trans-caval access for endoleak

embolization is associated with a higher

bleeding risk than percutaneous direct sac

puncture

• A. True

• B. False

Page 52: Approaches to type II Endoleaks: Transcaval, … to type II Endoleaks: Transcaval, transarterial, translumbar Saher Sabri ,MD University of Virginia

University of Virginia Health System, Department of Radiology & Medical Imaging

Q # 2 Trans-caval access for endoleak

embolization is associated with a higher

bleeding risk than percutaneous direct sac

puncture

• A. True

• B. False ( correct answer)