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TRABAJO FIN DE GRADO Proteolysis Targeting Chimera (PROTAC) I

2018 - ARCC Journal

PROTAC-mediated crosstalk between E3 ligases · Fig. S10 Homo-PROTAC 15a and hetero-PROTAC CRBN-6-5-5-VHL induce degradation of CRBN in all cell lines tested: (A) Human myeloma cell

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of Penetrant PROTAC® Degrader - Amazon S3 · 10/24/2019 · What is a PROTAC® Protein Degrader? 3 A proteolysis‐targeting chimera (PROTAC) degrader is a chimeric, modular small

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MDM2-Recruiting PROTAC Offers Superior, Synergistic ...MDM2-Recruiting PROTAC Offers Superior, Synergistic Antiproliferative Activity via Simultaneous Degradation of BRD4 and Stabilization

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Improved Accuracy for Modeling PROTAC-Mediated Ternary ......2020/07/10 · PROTAC modeling protocol, i.e., one that could give accurate results across different protein targets,

ARV-110: An oral androgen receptor PROTAC · Background: The Androgen Receptor (AR) remains the principal driver of castration-resistant prostate cancer during the transition from

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