art and science: the evolving picture of … - venice may2018_def_82… · european immunogenetics...

VENICE LIDO, MAY 9-12, 2018

EUROPEAN IMMUNOGENETICS

CONFERENCEAND HISTOCOMPATIBILITY32nd

ART AND SCIENCE: THE EVOLVING PICTURE OF IMMUNOGENETICS

www.efi2018.org

JOINT CONFERENCE EFI-AIBT

25th Annual Meeting of the Italian Society for Immunogenetics and Transplantation

Biology (AIBT)


CONFERENCEAND HISTOCOMPATIBILITY32nd ART AND SCIENCE:

THE EVOLVING PICTURE OF IMMUNOGENETICS

VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT


Biology (AIBT)



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TABLE OF CONTENTS

Committees ..................................................................................................... 4

Welcome Addresses .................................................................................... 7

General Information ..................................................................................... 8

Exhibition Plan and Listing .......................................................................... 14

Floor Plan ......................................................................................................... 14

Program at a glance ...................................................................................... 20

Associated Meetings .................................................................................... 26

25th AIBT Annual Meeting ........................................................................... 28

Program ............................................................................................................ 30Wednesday .................................................................................................. 30Thursday ....................................................................................................... 31Friday ............................................................................................................ 45Saturday ........................................................................................................ 55

Poster Presentations ...................................................................................... 58

Speakers - Chairs ........................................................................................... 94

Authors’ Index ................................................................................................ 96






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CommitteesLOCAL ORGANIZING COMMITTEE

CONGRESS CHAIRMANValeria Miotti (IT)

CONGRESS CO-CHAIRMENAntonio Amoroso (IT)

Carlo Carcassi (IT)

LOCAL ORGANIZING COMMITTEEMarco Andreani (IT)

Andrea Bontadini (IT)Emanuele Cozzi (IT)Maria E. Fasano (IT)Silvia Gregori (IT)

Luca Mascaretti (IT)Benedetta Mazzi (IT)

Lia Mele (IT)Franco Papola (IT)

Antonina Piazza (IT)Francesca Quintieri (IT)

Nicoletta Sacchi (IT)Manuela Testi (IT)

Luca Vago (IT)

ORGANIZING SECRETARIAT

Planning Congressi srlVia Guelfa 9

40138 Bologna (Italy)Ph. +39 051-300100 Ext. 130

Fax +39 [email protected]

www.planning.it



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EFI EXECUTIVE COMMITTEEElissaveta Naumova (BG), President

Joannis Mytilineos (DE) President ElectMats Bengtsson (SE), Secretary

Dave L. Roelen (NL), Deputy SecretaryGwendaline Guidicelli (FR), Treasurer

Katia Gagne (FR), Deputy Treasurer

EFI COUNCILLORSPierre-Antoine Gourraud (FR)

Teresa Kauke (DE)Neema Mayor (UK)Valeria Miotti (IT)Fatma Oguz (TR)Jean Villard (CH)

SCIENTIFIC COMMITTEE AND REVIEWERSCHAIR

Katharina Fleischhauer (DE)

MEMBERSRainer Blasczyk (DE)

Silvia Gregori (IT)Sebastiaan Heidt (NL)James Robinson (UK)

Ludvig Sollid (NO)James Traherne (UK)John Trowsdale (UK)

Luca Vago (IT)Lotte Wieten (NL)






Biology (AIBT)



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WELCOME ADDRESSESDear Colleagues and Friends,The 32nd European Immunogenetics and Histocompatibility Conference, joint with the 25th AIBT (Italian Society for Immunogenetics and Transplantation Biology) annual meeting, will be held in Venice, Italy from 9th to 12th of May, 2018.“Art and Science: the evolving picture of Immunogenetics” is the motto of EFI2018 that reflects the dynamism of the Immunogenetics World and its ability to get involved in new addictive biomedical fields, like Leonardo’s masterpiece. I am confident that the meeting will be interesting and exciting, enriching you with the most recent updates in Tissue Typing, Immunogenetics and Transplantation Immunology.The conference will take place in the historical buildings of Palazzo del Cinema and Palazzo del Casinò, located in Venice Lido, the quiet, peaceful and green narrow island that stretches between the open sea and the lagoon, just 15 minutes far from St. Mark’s Square.Marvellous Venice, where, everybody knows, there is no traffic jam and you can wander around the labyrinth of narrow cobbled streets and over the countless bridges that criss-cross the canals. You shall not rush and you might lose track of time. Every corner is unique and worth a look for its artistic value or romantic atmosphere.You can get about Venice by water buses, water-taxis or “Gondolas”, which allows you to visit canals and the lagoon.Don’t miss the chance to see “Ponte dei Sospiri” (Bridge of Sighs) where the convicts saw the lagoon before their imprisonment, sighing at their final view of beautiful Venice through the window before being taken down to their cells; Canal Grande (Grand Canal); Rialto Bridge, Churches, Art-galleries, Murano (famous for its glass works) and Burano (famous for the lace shops).It is a great honour and pleasure to invite you to such a unique, romantic, slow, fascinating place named Venice.Looking forward to seeing you all

Valeria MiottiOn behalf of AIBT

and Conference Co-ChairsCarlo Carcassi and Antonio Amoroso






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GENERAL INFORMATIONCONFERENCE VENUEThe Conference will take place in Venice Lido, at Palazzo del Cinema and Palazzo del Casinò.Lungomare Guglielmo Marconi, 186130126 Lido di Venezia

The Palazzo del Cinema is the main facility and screening theatre of the Venice Film Festival. It was built according to the modernist trends of the 1930s, and inaugurated on 10th August 1937 on the occasion of the fifth edition of the festival.In this building will be held:• Opening Ceremony• Plenary Sessions• Closing Ceremony

The Palazzo del Casinò was designed by the Chief Engineer of the City of Venice Eugenio Miozzi in the Rationalist style, influenced by the Fascist architecture of the 1930s and built in the record time of 8 months in 1938. In this building will be held:• 25th AIBT Annual Meeting• Parallel Sessions• Luncheon Sessions• Scientific Poster Reception

PALAZZO CASINÒ

PALAZZO CINEMA



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REGISTRATION AND INFORMATION DESKS The registration desks are located on level 1.OPENING HOURSWednesday 9 May 2018 08:00 - 20:00 Thursday 10 May 2018 08:00 - 19:00 Friday 11 May 2018 08:00 - 19:00 Saturday 12 May 2018 08:00 - 14:00

ON SITE REGISTRATION FEESMember 560 EuroNon Member 620 EuroStudent 395 EuroTechnician 395 EuroAccompanying Person 110 EuroGala Dinner 70 Euro

REGISTRATION INCLUDES:• VAT• Access to the conference sessions (not included for Accompanying Persons)• Opening Ceremony and Welcome Reception• Coffee Breaks• Lunches (not included for Accompanying Persons)• VENEZIA UNICA City Card

COFFEE BREAKS Coffee and refreshments will be served to delegates at several points at the exhibition area.

LUNCH BOX Tickets are required for the lunch box and are provided with the registration package. Additional tickets for guests can be purchased through the Registration desk.

CERTIFICATE OF ATTENDANCEThe certificate of attendance will be sent by email after the Conference.






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GENERAL INFORMATIONPUBLIC TRANSPORTATIONVenice’s official City Pass VENEZIA UNICA is a card that offers three days of public transportation use with the ACTV Company in the city area (the card will be activated for the whole days of May 10, 11 and 12).Warning: The fare includes the transport of only one piece of luggage and its three dimensions must not exceed 150 cm.The card will be delivered at the Congress Registration Desk.This card allows you to catch all vaporetto and buses in the City of Venice and buses in Mestre. The Tronchetto parking area in Venice is not reachable by bus, but only by the people mover. PLEASE NOTE THAT PEOPLE MOVER FARE IS NOT INCLUDED IN THE VENEZIA UNICA CARD.The card also includes the free use of the speedboat from Punta Sabbioni to Venice Lido, but it does NOT include bus transportation in Punta Sabbioni (one way fare 1,50 €).The public transportation from/to Marco Polo Airport is provided by another company, named Alilaguna, and is not included in VENEZIA UNICA card.

CONFERENCE APPFull program and more information regarding the Conference are available at the 32nd EFI conference application for iOS and Android.QR CODE to download the conference app.

WI-FIFree Wi-Fi is provided for all delegates and Exhibitors attending the Conference. Network ConventionCenterpassword EFI2018!

EFI BOOTHThe EFI Booth is situated in the Exhibition Hall on level 3.Membership secretary is available:Thursday 10 May 2018 08:30 - 17:00 Friday 11 May 2018 08:30 - 17:00



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SPEAKER READY ROOMThe Speaker Ready room is located on level 1. All speakers should deliver their presentations at least 2 hours prior to their speech. OPENING HOURSWednesday 9 May 2018 15:00 - 18:30Thursday 10 May 2018 08:00 - 19:00 Friday 11 May 2018 08:00 - 18:30 Saturday 12 May 2018 08:00 - 13:00

POSTERS The Poster Area is located on level 3. The poster panels will be numbered. Please refer to the final poster number of your submission which has been communicated to you earlier. Posters can be mounted on Thursday May 10th (from 8:00 to 10:30) and should be removed on Saturday, May 12th by 9:00. Any posters remaining on poster boards after this time will be disposed of by the organizers. Posters should be attached to poster boards using double sided tape - supply of the tape will be available at the poster area for all poster presenters. Posters will be presented during the Poster Session in the late afternoon of Thursday, May 10th. The presenting author should be available beside his/her poster in order to discuss the data with the attendants.

AIBT ANNUAL MEETINGPlease note that the official language of the AIBT Meeting will be Italian.No simultaneous translation will be provided.

AIBT MEETING - CONTINUING MEDICAL EDUCATION (CME) Planning Congressi S.r.l. is a CME Provider - identification code no. 38 - and has assigned to the event no. 3,5 credits for Biologists, Chemists, Physicians and Technicians.Please be aware that for the acquisition of credits it is mandatory to have attended the 90% of the whole duration of the congress and selected at least the 75% of correct answers of the CME questionnaire.






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GENERAL INFORMATIONEFI CONGRESS - CPE AND CPD CREDITSFor the first time at this Conference, Certificates regarding CME/CPD credits awarded will only be provided to delegates after the meeting, following completion of a short survey.The survey is designed to capture information about the meeting, speakers and venue and will inform future conference organisation. The survey link will be sent to delegates by email immediately following the Conference. We hope delegates understand the usefulness of this meeting evaluation survey and of the provision of EFI Educational Credits and ASHI continuing education credits.

EXHIBITION The Exhibition will be held on level 1 and 3.OPENING HOURS Wednesday 9 May 2018 09:00 - 19:00 Thursday 10 May 2018 08:00 - 19:30 Friday 11 May 2018 08:00 - 19:00

SOCIAL PROGRAM

EFI Inspectors Dinner (by invitation only) Tuesday 8 May, 19:00 - “La Favorita” Restaurant, Venice LidoWelcome Reception Wednesday 9 May, 19:30 - Palazzo Cinema FoyerTulip Run (Sponsored by GenDx) Thursday 10 May, 07:00-08:00 Scientific Poster Reception (Sponsored by One Lambda and Lagitre, srl)Thursday 10 May, 18:00-20:00 - Palazzo del Casinò (3rd floor)Ceppellini Dinner (by invitation only) Thursday 10 May, 20:30 - “Da Celeste” Restaurant - Pellestrina IslandSpeakers Dinner (by invitation only) Thursday 10 May, 20:30 - “Relais Alberti”, Venice LidoConference Gala Dinner (additional fee) Friday 11 May, 20:45 - Grand Hotel Excelsior, Venice Lido



Biology (AIBT)

EXHIBITION PLAN AND LISTING FLOOR PLAN






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Biology (AIBT)







Biology (AIBT)

PROGRAM AT A GLANCE






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TIME TUESDAY, 8th MAY

ROOMPalazzo

del CinemaFoyer

Palazzo del CasinòCasinò Room

1st floor

Palazzo del CasinòMosaici 1 Room

3rd floor


3rd floor

Palazzo del CasinòBuy Room2nd floor

08:00-08:30

08:30-09:00 EBTI Assembly Meeting09:00-09:30

ESHI diploma examination

09:30-10:00

Accreditation Inspectors Workshop

10:00-10:30

10:30-11:00

11:00-11:30

11:30-12:00

IBMDR Meeting

12:00-12:30

12:30-13:00

13:00-13:30

13:30-14:00

14:00-14:30

14:30-15:00

15:00-15:30

15:30-16:00

16:00-16:30

16:30-17:00

17:00-17:30

17:30-18:00

18:00-:18:30

18:30-19:00

19:00-19:30

19:30-20:00



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TIME WEDNESDAY 9th MAY

ROOMPalazzo

del CinemaFoyer

Palazzo del Casinò

Casinò Room

1st floor

Palazzo del CasinòPerla Room

1st floor

Palazzo del CasinòAmici Room

2nd floor

Palazzo del CasinòMangano

Room2nd floor

Palazzo del CasinòRossi Drago

Room2nd floor

Palazzo del CasinòMartinelli

Room2nd floor


08:00-08:30

08:30-09:00

External Proficiency

Testing Committee

Executive Committee

Meeting

Standards Committee

Meeting

09:00-09:30

25th AIBT Annual

Meeting

Accreditation Committee

Meeting

09:30-10:00

10:00-10:30

10:30-11:00

11:00-11:30

11:30-12:00

12:00-12:30

12:30-13:00

13:00-13:30

13:30-14:00

Education Committee

14:00-14:30

14:30-15:00

15:00-15:30 Open Meeting of

the Population Genetics Working Group

15:30-16:00

16:00-16:30

16:30-17:00

17:00-17:30

17:30-18:00

Opening Ceremony

18:00-:18:30

18:30-19:00

19:00-19:30

19:30-20:00

Welcome Reception

20:00-20:30

20:30-21:00

21:00-21:30






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TIME THURSDAY, 10th MAY

ROOMPalazzo

del CinemaAuditorium

Palazzo del Casinò

Casinò Room1st floor

Palazzo del CasinòMosaici 1

Room3rd floor

Palazzo del CasinòMosaici 2

Room3rd floor


1st floor


Palazzo del CasinòMartinelli

Room2nd floor

08:00-08:30

08:30-09:00 PLENARY SESSION 1 Governance of immune-

modulation in transplantation

09:00-09:30

09:30-10:00

10:00-10:20 Coffee break & Poster viewing

Scientific Committee

Meeting

10:20-10:50

Meet the Expert 1

ESHI Diploma

Oral Session 1MHC Evolution - Anthropology

- Population Genetics

Oral Session 2New

Technologies and

Bioinformatics

Teaching Session 1 How NGS

technology is changing the way of HLA

typing

10:50-11:20

11:20-11.50

11.50-12.00 Pause12:00-12:30 Luncheon

SessionCareDx

Luncheon SessionGenDx

Luncheon Session

One Lambda Executive Committee

and Co-ordinators

Meeting

12:30-13:00

13:00-13:30 Lunch Box13:30-14:00 Luncheon

SessionImmucor

Luncheon SessionOmixon

Luncheon Session

One Lambda14:00-14:30

14:30-14:40 Pause

14:40-15:10Meet the Expert 2

EPT External proficiency

testing

Oral Session 3Immunotherapy - Gene Therapy - Cellular Therapy

Oral Session 4Haematopoietic

Stem Cell Transplantation

Teaching Session 2

Clinical impact of

de-novo HLA antibodies in solid organ

transplantation

15:10-15:40

15:40-16:10

16:10-16:30 Coffee break & Poster viewing16:30-17:00 PLENARY

SESSION 2Solid Organ

Transplantation17:00-17:30

17:30-:18:00

18:00-18:30

Scientific Poster Reception18:30-19:00

19:00-19:30

19.30-20.00



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TIME FRIDAY, 11th MAY

ROOMPalazzo



3rd floor

Palazzo del Casinò

Mosaici 2 Room3rd floor


1st floor 08:00-08:30

08:30-09:00PLENARY SESSION 3HSCT Current clinical

perspectives09:00-09:30

09:30-10:00

10:00-10:20 Coffee break & Poster viewing

10:20-10:50

Oral Session 5Solid Organ Transplantation

Oral Session 6NK and Miscellaneous

Teaching Session 3 Tools for a successful HSCT:

evaluation of HLA allele frequencies, anti-HLA

antibodies, structural and expression models for permissive mismatches

10:50-11:20

11:20-11.50

11.50-12.00 Pause12:00-12:30 Luncheon Session

Bag HealthcareLuncheon Session


13:00-13:30 Lunch Box13:30-14:00 Luncheon Session

HistogeneticsLuncheon Session


14:30-14:40 Pause

14:40-15:10

SPECIAL JOINT SESSIONWMDA and EFI

Oral Session 7Reproduction,

Autoimmunity, Infection & Cancer

Teaching Session 4 How to prepare for an

inspection: demonstrating how quality standards

are met

15:10-15:40

15:40-16:10

16:10-16:30 Coffee break & Poster viewing16:30-17:00

PLENARY SESSION 4 Immunogenetics

beyond HLA17:00-17:30

17:30-:18:00

18:00-18:30

EFI General Assembly18:30-19:00

19:00-19:30

19.30-20.00

20.00-20.30

20.30-24.00 Conference Gala Dinner






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TIME SATURDAY, 12th MAY

ROOMPalazzo


Palazzo del CasinòCasinò Room

1st floor


3rd floor


3rd floor


1st floor08:00-08:30

08:30-09:00Best Abstract

Session09:00-09:30

09:30-10:00

10:00-10:30 17th and 18th IHW reports

10:30-10:50 Coffee Break10:50-11:20 PLENARY

SESSION 5 New Frontiers in Immunogenetics

11:20-11.50

11.50-12.20

12:20-12:50 Closing Lecture12:50-13:30 Closing Ceremony



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ASSOCIATED MEETINGS

25th AIBT ANNUAL MEETING

PROGRAM






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ASSOCIATED MEETINGSTuesday 8 May 2018

CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR)

8:30-9:30 EBTI Assembly MeetingChairperson: Marco Andreani

11:30-18:30 IBMDR MeetingChairperson: Nicoletta Sacchi

BUY ROOM - PALAZZO CASINÒ (2nd FLOOR)

09:00-14:00 ESHI diploma examinationChairperson: David Turner

FOYER - PALAZZO CINEMA

9:30-16:30 Accreditation Inspectors WorkshopChairperson: Andrea Harmer

Wednesday 9 May 2018AMICI ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-16:00 External Proficiency Testing CommitteeChairperson: Falko Heinemann

MANGANO ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-16:30 Executive Committee MeetingChairperson: Elissaveta Naumova

ROSSI DRAGO ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-16:00 Standards Committee MeetingChairperson: Juha Peräsaari



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Wednesday 9 May 2018MARTINELLI ROOM - PALAZZO CASINÒ (2nd FLOOR)

9:00-16:30 Accreditation Committee MeetingChairperson: Andrea Harmer

BUY ROOM - PALAZZO CASINÒ (2nd FLOOR)

13:30-17:00 Education CommitteeChairperson: David Turner

CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR)

15:00-16:30 Open Meeting of the Population Genetics Working GroupChairperson: Alicia Sanchez-Mazas

Thursday 10 May 2018BUY ROOM - PALAZZO CASINÒ (2nd FLOOR)

10:00-12:00 Scientific Committee MeetingChairperson: Katharina Fleischhauer

MARTINELLI ROOM - PALAZZO CASINÒ (2nd FLOOR)

12:15-14:30 Executive Committee and Co-ordinators MeetingChairperson: Elissaveta Naumova

Friday 11 May 2018 PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

18.00-19.30 EFI General Assembly






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25th AIBT ANNUAL MEETING Accreditato ECM

Wednesday 9 May 2018PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

9:00 Apertura lavori

I SESSIONEModeratori: Valeria Miotti, Manuela Testi

9:30 Il donatore non familiare, adulto e cord: quali prospettive nell’era del trapianto aploidentico

Nicoletta Sacchi10:00 Anticorpi DSA nel Trapianto di CSE, gestione e

desensibilizzazione Giovanni Rombolà10:30 Metodologia di studio del chimerismo in relazione

alle diverse tipologie di trapianto di CSE: ricaduta clinica Marco Andreani11:00 Nuovi targets della risposta immune umorale nel trapianto

d’organo Emanuele Cozzi

11:30 Coffee break

WED

NES

DAY



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Wednesday 9 May 2018PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

II SESSIONEModeratori: Lia Mele, Antonina Piazza

11:45 Epigenetica e nuove tecnologie: cosa cambia nell’associazione HLA e malattie immunomediate

Carlo Carcassi12:15 Il Controllo di qualità Esterno Francesca Quintieri

13:30 Lunch14:45 AIBT nella storia Valerio Misefari15:15 Conclusione lavori15:30 Assemblea dei Soci

WED

NES

DAY






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PROGRAMWednesday 9 May 2018OPENING CEREMONY AUDITORIUM - PALAZZO CINEMA

17:30-18:00 Welcome Addresses Valeria Miotti, Carlo Carcassi, Antonio Amoroso,

Elissaveta Naumova, Alessandro Nanni Costa

18:00-18:30 In memory of Jon van Rood Frans H.J. Claas18:30-18:55 Julia Bodmer Award Katharina Fleischhauer18:55-19:00 HLA Award Steven G.E. Marsh19:00-19:30 Ceppellini Lecture Elissaveta Naumova19:30-20:00 Sounds from Italy - Classic and cinema

20:00-21:30 Welcome Reception

WED

NES

DAY



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Thursday 10 May 2018PLENARY SESSION 1 AUDITORIUM - PALAZZO CINEMA

Governance of immune-modulation in transplantationChairpersons: Frans H.J. Claas, Silvia Gregori

8:30-9:00 Mesenchimal stem cells in transplantation Katarina K. Le Blanc9:00-9:30 Exosome Adrian E. Morelli9:30-10:00 Innate lymphoid cells Hergen Spits

10:00-10:20 Coffee break & Poster viewing PALAZZO CASINÒ

THUR

SDAY






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Thursday 10 May 2018PARALLEL SESSIONS CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR)

10:20-11:50 Meet the Expert 1 - ESHI Diploma Marco Andreani, David Turner

• Overview of the ESHI Diploma David Turner

• Preparation for the Application and Examination Marco Andreani

• New EFI CME/CPD scheme David Turner

• Q&A

MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

10:20-11:50 Oral Session 1: MHC Evolution - Anthropology - Population Genetics

Chairpersons: Pierre-Antoine Gourraud, Alicia Sanchez-MazasO9 AGE-DEPENDENT CHANGES IN REGULATION OF HLA-DQ GENE EXPRESSION (WITHDRAWN)

Marie Cerna 1, Martin Chmel 1, Michael Hudec 1, Adela Rihova 1, Elena Silhova 21Charles University, Third Faculty of Medicine, Prague, Czech Republic - 2University Hospital Kralovske Vinohrady, Prague, Czech Republic

O10 THE DISTRIBUTION OF HUMAN LEUKOCYTE ANTIGEN A AND B GENES IN POPULATIONS IS STRONGLY SHAPED BY THEIR FUNCTIONAL RELATIONSHIPDa Di 1, Jose M. Nunes 1, Alicia Sanchez-Mazas 11University of Geneva, Geneva, Switzerland

O11 HLA ALLELE AND HAPLOTYPE FREQUENCIES CHARACTERIZED USING NEXT-GENERATION SEQUENCING METHODS IN UNRELATED WORLD-WIDE POPULATIONS: SUMMARY FROM THE 17TH INTERNATIONAL HLA AND IMMUNOGENETICS WORKSHOPLisa E. Creary 1, Chia-Jung Chang 2, Gonzalo Montero-Martin 1, Kalyan C. Mallempati 3, Sridevi Gangavarapu 3, Kazutoyo Osoegawa 3, Tamara Vayntrub 3, Marcelo A. Fernández-Viña 11Stanford University School of Medicine, Palo Alto, United States of America - 2Stanford Genome Technology Center, Palo Alto, United States of America - 3Stanford Blood Center, Palo Alto, United States of America

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Thursday 10 May 2018PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

O12 THE MICRORNA BINDING-SITE REGION OF MHC GENES PLACED IN AN EVOLUTIONARY CONTEXTCorrine M.C. Heijmans 1, Cristy Verzijl 1, Hans J.H.A. Rijnaard 1, Jeffrey Oliveira 1, Kaat Tielens 1, Natasja G. de Groot 1, Ronald E. Bontrop 11Biomedical Primate Research Centre, Rijswijk, Netherlands

O13 HLA CLASS I HAPLOTYPE DIVERSITY IS CONSISTENT WITH SELECTION FOR FREQUENT EXISTING HAPLOTYPESYoram Louzoun 1, Loren Gragert 2, Martin Maiers 3, Idan Alter 1, Stephanie Fingerson 31Bar Ilan University, Ramat Gan, Israel - 2Tulane University, New Orleans, United States of America - 3National Marrow Donor Program, Minneapolis, MN, United States of America

O14 MANY MHC-B ALLELES OF THE BONOBO SHARE SIMILAR FEATURES WITH HLA ALLELES THAT ARE ASSOCIATED WITH PROTECTION FROM MALARIANatasja G. de Groot 1, Corrine M.C. Heijmans 1, Philippe Helsen 2, Jeroen M.G. Stevens 2, Ronald E. Bontrop 11Biomedical Primate Research Centre, Rijswijk, Netherlands - 2Royal Zoological Society of Antwerp, Antwerp, Belgium

O15 EVOLUTIONARY FATE OF NEW ALLELESPedro Cano 11Moffitt Cancer Center, Tampa, United States of America

O16 ANCIENT ORIGIN OF TWO CLADES OF DPB1 ALLELESGerhard Schöfl 1, Steffen Klasberg 1, Kathrin Lang 1, Alexander H. Schmidt 2, Vinzenz Lange 11DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany

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10:20-11:50 Oral Session 2: New Technologies and Bioinformatics

Chairpersons: Emanuele Cozzi, Eric SpieringsO17 NEXT-GENERATION TARGET CAPTURE AND DIRECT LONG READ SEQUENCING OF THE

MAJOR HISTOCOMPATIBILITY COMPLEX (MHC)Johannes Dapprich 1, Oscar A. Pérez-Escobar 2, Sidonie Bellot 2, Jessica Rothe 3, Stefanie Köcher 3, Marion Nagy 3, Mehmet Tevfik Dorak 4, Stephen Rudd 5, Fabian Grunz 6, Nicolas Krezdorn 6, Klaus Hoffmeier 61Generation Biotech, Lawrenceville, United States of America - 2Royal Botanic Gardens Kew, Richmond, United Kingdom (Great Britain) - 3Institute for Legal Medicine, Berlin, Germany - 4Kingston University, London, United Kingdom (Great Britain) - 5Oxford Nanopore Technologies, Oxford, United Kingdom (Great Britain) - 6GenXPro, Frankfurt, Germany

O18 HIGH RESOLUTION HAPLOTYPE ANALYSES OF CLASSICAL HLA GENES IN FAMILIES FOR THE 17TH INTERNATIONAL HLA AND IMMUNOGENETICS WORKSHOPKazutoyo Osoegawa 1, Lisa E. Creary 2, Kalyan Mallempati 1, Sridevi Gangavarapu 1, Steven J. Mack 3, Medhat Askar 4, Marcelo Fernandez Vina 21Stanford Blood Center, Palo Alto, United States of America - 2Stanford University School of Medicine, Palo Alto, United States of America - 3Children’s Hospital Oakland Research Institute, Oakland, United States of America - 4Baylor University Medical Center, Dallas, United States of America

O19 IPD-MHC DATABASE: IMPROVING TOOLS FOR THE ANALYSIS OF THE MAJOR HISTOCOMPATIBILITY COMPLEXGiuseppe Maccari 1, James Robinson 2, Natasja G. de Groot 3, Nel Otting 3, Ronald E. Brontop 3, John A. Hammond 4, Steven GE. Marsh 21The Pirbright Institute and Anthony Nolan, Guildford, United Kingdom (Great Britain) - 2Anthony Nolan and UCL Cancer Institute, London, United Kingdom (Great Britain) - 3Biomedical Primate Research Centre, Rijswijk, Netherlands - 4The Pirbright Institute, Guildford, United Kingdom (Great Britain)

O20 IS NANOPORE SEQUENCING READY FOR PRIME TIME? ACCURATE HLA CLASS I GENOTYPING AND DETECTION OF NOVEL SEQUENCE VARIANTS BASED ON FULL GENE SEQUENCE ANALYSISVineeth Surendranath 1, Kathrin Lang 1, Alexander H. Schmidt 2, Gerhard Schöfl 1, Vinzenz Lange 11DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany

O21 SIMULATING THROMBOCYTE TRANSFUSIONS TO INVESTIGATE THE ROLE OF T-HELPER AND B-CELL EPITOPES ON THE RISK FOR PLATELET REFRACTORINESSKirsten Geneugelijk 1, Talitha de Hoop 1, Eric Borst 1, Eric Spierings 11University Medical Center Utrecht, Utrecht, Netherlands

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O22 CONVERGING EVOLUTION LEADS TO NEAR MAXIMAL JUNCTION DIVERSITY THROUGH PARALLEL MECHANISMS IN B AND T CELL RECEPTORSYoram Louzoun 1, Jennifer Benichou 11Bar Ilan University, Ramat Gan, Israel

O23 FULL-LENGTH HLA AND KIR ALLELE SEQUENCE CHARACTERIZATION WITH DR2SSteffen Klasberg 1, Kuntal Worah 1, Marie Günther 1, Kathrin Lang 1, Alexander H. Schmidt 2, Vinzenz Lange 1, Gerhard Schöfl 11DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany

O24 COMPUTATIONAL SIMULATIONS DEMONSTRATE THE FEASIBILITY AND BENEFIT OF EPITOPE MATCHING FOR KIDNEY TRANSPLANTATIONMatthias Niemann 1, Nils Lachmann 2, Oliver Staeck 2, Eric Spierings 31PIRCHE AG, Berlin, Germany - 2Charité - Universitätsmedizin Berlin, Berlin, Germany - 3UMC Utrecht, Utrecht, Netherlands

PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

10:20-11:50 Teaching Session 1 How NGS technology is changing the way of HLA typing Joannis Mytilineos, Sarah Patricia Peacock

• The whole gene: Application and implementation of whole gene sequencing in the clinical lab

Katy Latham• NGS in a Transplant Center: a French experience

Béatrice Bardy• Sequencing with nanopores: current status and near future

potential Vineeth Surendranath

• General discussion & close

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Thursday 10 May 2018LUNCHEON SESSIONS CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR)

12:00-13:00 Luncheon Session - CareDxWelcome Roswitha Keller, PhD VP, Transplant Laboratory Solutions, CareDx International, Vienna, AustriaOlerup QTYPE development, utilizing the full potential of a primer-probe based assay in HLA typing Ben Passey, Development Manager, CareDx International, Stockholm, SwedenSpeed and precision in real time; Results from an Olerup QTYPE Multicentre Clinical Validation Study John Lunz, PhD D(ABHI), Director of the Histocompatibility Laboratory, Gift of Hope Organ & Tissue Donor Network, Itasca IL, USA

13:00-13:30 Lunch13:30-14:30 Luncheon Session - Immucor

Clinical Relevance of Complement Activating Pre-formed Donor Specific Antibodies in Crossmatch Positive HLA-incompatible Renal Transplantation: a Multicentre StudyDr. Olivia Shaw, Viapath at Guy’s Hospital, Clinical Transplantation Lab at Guy’s Hospital, Clin Transpl Dept., New City CourtPost Transplant Monitoring - kSORT Analysis in a Real World ContextDr. Michael Spigarelli, Vice President Medical Affairs - Immucor Inc.

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Thursday 10 May 2018LUNCHEON SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR)

12:00-13:00 Luncheon Session - GenDxImprovements in Transplantation DiagnosticsChairperson: Wietse MulderWhat is next in NGS HLA typing Daniel Mathow, PhD Senior Sales & Application Manager, GenDxDaily practice of HLA typing in a clinical settingMarte Viken, PhD Senior Scientific Advisor, Oslo University Hospital, NorwayRecent improvements in NGSengine to make life easierErik Rozemuller, PhD Senior Scientist Bioinformatics, GenDxUpdate in chimerism clinical practice Dominique Bories, MD, PhD Head Moleculair Onco-Hematology Laboratory, Henri Mondor Hospital Creteil, FranceChimerism monitoring made easy Maarten Penning, PhD CTO, GenDxConclusion Wietse Mulder, PhD CEO, GenDx

13:00-13:30 Lunch13:30-14:30 Luncheon Session - Omixon

Holotyping without Borders - Holotype HLA V2. Experiences Within and from Outside the EU for the Benefit of the Wider Transplant CommunityThe Lunchtime Symposium will focus on the experiences of existing Holotype HLA users in- and outside the European Union. Three Guest Speakers, Vera Siffnerova (UHKT), Dr. Elena Shagimardanova (Kazan Federal University) and Derrick Nelson (South African National Blood Service) are going to share their experience with the new Holotype HLA V.2. protocol. Omixon’s CEO, Dr. Peter Meintjes will announce major product innovations and new directions for the company.- Welcome & Introduction- Presentations by Guest Speakers- Announcement of Major Product Enhancements

by Dr. Peter Meintjes (CEO, Omixon)

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Thursday 10 May 2018LUNCHEON SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

12:00-13:00 Luncheon Session - One LambdaDefining 11-HLA loci in a diverse cord blood bank using the AllType™ NGS AssaysSandra Guerra, Ph.DNational H&I Service Development LaboratoryPost-Doctoral Research ScientistNHS Blood and TransplantLondon, United Kingdom

13:00-13:30 Lunch13:30-14:30 Luncheon Session - One Lambda

Epitope Matching vs. HLA Matching in Organ TransplantationChris Wiebe, MDNephrologist, University of ManitobaCanadian Blood ServicesWinnepeg, Manitoba Canada

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Thursday 10 May 2018PARALLEL SESSIONS CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR)

14:40-16:10 Meet the Expert 2 - EPT External proficiency testing Falko Heinemann

• Extending the Spectrum of EPT in H&I• EPT in H&I: From History to New Developments• Organization of EPT: Schemes, Workshops and Inter-Laboratory

Exchanges • Specialist EPT Schemes: HNA, HPA, mHAg and KIR• The Impact of New Technology on EPT: Next Generation

Sequencing and Single Antigen Bead tests - ‘Result based’ or ‘method based’ assessment?

MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

14:40-16:10 Oral Session 3: Immunotherapy - Gene Therapy - Cellular Therapy

Chairpersons: Rainer Blasczyk, Mats BengtssonO25 NKG2A EXPRESSION IS NOT PER SE DETRIMENTAL FOR THE ANTI-MULTIPLE MYELOMA

ACTIVITY OF HIGH DOSE IL-2 ACTIVATED NATURAL KILLER CELLS IN AN IN VITRO SYSTEM MIMICKING THE TUMOR MICROENVIRONMENTNiken M. Mahaweni 1, Femke Ehlers 1, Subhashis Sarkar 1, Johanna W. H. Janssen 1, Marcel G. Tilanus 1, Gerard M. J. Bos 1, Lotte Wieten 11Maastricht University Medical Center, Maastricht, Netherlands

O26 ALLOREACTIVE NATURAL KILLER CELL THERAPY AS NOVEL APPROACH FOR BREAST CANCERFemke Ehlers 1, Michel van Gelder 1, Nicky Beelen 1, Marcel Tilanus 1, Marjolein Smits 1, Loes Kooreman 1, Gerard Bos 1, Lotte Wieten 11Maastricht University Medical Center, Maastricht, Netherlands

O27 IN VIVO CRISPR/CAS9 SCREENING FOR THE IDENTIFICATION OF NOVEL PLAYERS IN LEUKEMIA IMMUNE ESCAPEEleonora Draghi 1, Alessandro Migliara 2, Giacomo Oliveira 1, Arnolda Jakovija 1, Nice Turazzi 1, Antonella Antonelli 1, Barbara Camisa 1, Francesco Santaniello 1, Monica Volpin 1, Daniela Cesana 1, Eugenio Montini 1, Bernard Gentner 2, Attilio Bondanza 1, Chiara Bonini 1, Fabio Ciceri 1, Angelo Lombardo 2, Luca Vago 11San Raffaele Hospital Scientific Institute, Milan, Italy - 2San Raffaele-Telethon Institute for Gene Therapy, Milan, Italy

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O28 EXPLORING FCγRIIIA GENE VARIATION: NOVEL APPROACHES TO EXAMINE FULL-LENGTH GENE POLYMORPHISMSTimo I. Olieslagers 1, Niken M. Mahaweni 1, Ivan Rivas Olivares 1, Stefan Molenbroeck 1, Gerard M. Bos 1, Mathijs Groeneweg 1, Marcel G.J. Tilanus 1, Christina E.M. Voorter 1, Lotte Wieten 11Maastricht University Medical Center, Maastricht, Netherlands

O29 MULTIKINASES INHIBITOR IMPAIRING VASCULATURE FACILITATES THE IMMUNE RESPONSIVENESS AGAINST LEUKEMIA BY DECREASING THE POTENTIAL OF REGULATORY CELLSEmilia Jaskuła 1, Janusz Lange 2, Mariola Sedzimirska 2, Helena Pakos 2, Michalina Krydel 2, Jolanta Bochenska 2, Iwona Maszko-Wodzinska 2, Andrzej Lange 11L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences/ Lower Silesian Center for Cellular Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland - 2Lower Silesian Center for Cellular Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland

O30 DONOR/RECIPIENT IL6 GENOTYPE IS NOT ASSOCIATED WITH SERUM PROFILE OF INFLAMMATION-ASSOCIATED MOLECULES IN PATIENTS AFTER ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATIONFrantisek Mrazek 1, Petra Schneiderova 1, Ludek Raida 1, Eva Kriegova 1, Adam Kuba 1, Martin Petrek 1, Zuzana Ambruzova 11Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic

O31 FIRST PILOT STUDY ON THE EFFICACY OF INTRAVENOUS IMMUNOGLOBULINS (IVIG) IN BEHCET PATIENTS: IMPROVEMENT OF DISEASE ACTIVITY INDEX AND INFLAMMATORY MARKERSMartina Finocchi 1, Giacomo Emmi 1, Elena Silvestri 1, Annalisa De Silvestri 2, Carmine Tinelli 2 Cristina Capittini 21Careggi University Hospital, University of Florence, Florence, Italy - 2IRCCS Policlinico San Matteo Foundation, Pavia, Italy

O32 VACCINATION WITH A PNEUMOCOCCAL CONJUGATE VACCINE DOES NOT INDUCE HLA ANTIBODIES IN KIDNEY TRANSPLANT RECIPIENTSMonika Lindemann 1, Simon Heckel 2, Benjamin Wilde 3, Peter A. Horn 1, Falko M. Heinemann 1, Oliver Witzke 41Institute for Transfusion Medicine, University Hospital, Essen, Germany - 2Institute for Transfusion Medicine, Department of Infectious Diseases, Department of Nephrology, University Hospital, Essen, Germany - 3Department of Nephrology, University Hospital, Essen, Germany - 4Department of Infectious Diseases, University Hospital, Essen, Germany

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14:40-16:10 Oral Session 4: Haematopoietic Stem Cell Transplantation

Chairpersons: Manuela Testi, Jean VillardO33 BETTER HLA MATCHING AS REVEALED ONLY BY ULTRA-HIGH RESOLUTION HLA TYPING

RESULTS IN SUPERIOR OVERALL SURVIVALNeema P. Mayor 1, James D. Hayhurst 2, Thomas R. Turner 1, Richard M. Szydlo 3, Bronwen E. Shaw 4, Will P. Bultitude 1, Jex-Ray Sayno 2, Franco Tavarozzi 2, Katy Latham 2, Chloe Anthias 5, James Robinson 1, Henny Braund 2, Robert Danby 6, Julia Perry 7, Marie C. Wilson 8, Adrian J. Bloor 9, Andrew Clark 10, Stephen MacKinnon 11, David I. Marks 12, Antonio Pagliuca 13, Michael N. Potter 14, Victoria T. Potter 13, Nigel H. Russell 15, Kirsty J. Thomson 11, J. Alejandro Madrigal 1, Steven GE. Marsh 11Anthony Nolan Research Institute & UCL Cancer Institute, London, United Kingdom (Great Britain) - 2Anthony Nolan Research Institute, London, United Kingdom (Great Britain) - 3Anthony Nolan Research Institute & Imperial College, London, United Kingdom (Great Britain) - 4CIBMTR and Froedtert & the Medical College of Wisconsin, Milwaukee, United States of America - 5Anthony Nolan Research Institute & Royal Marsden NHS Foundation Trust, London, United Kingdom (Great Britain) - 6Anthony Nolan Research Institute & Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, London, United Kingdom (Great Britain) - 7British Society of Blood and Marrow Transplantation (BSBMT), London, United Kingdom (Great Britain) - 8Anthony Nolan Research Institute & British Society of Blood and Marrow Transplantation (BSBMT), London, United Kingdom (Great Britain) - 9The Christie NHS Foundation Trust, Manchester, United Kingdom (Great Britain) - 10West of Scotland Cancer Centre, Gartnavel Hospital, Glasgow, United Kingdom (Great Britain) - 11University College London Hospitals, London, United Kingdom (Great Britain) - 12University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom (Great Britain) - 13Kings College Hospital, London, United Kingdom (Great Britain) - 14Royal Marsden NHS Foundation Trust, Sutton, United Kingdom (Great Britain) - 15Nottingham University Hospital, Nottingham, United Kingdom (Great Britain)

O34 INVESTIGATING THE RECONSTITUTION OF THE T LYMPHOCYTE REPERTOIRE BY HIGH THROUGHPUT SEQUENCING AT ONE YEAR FOLLOWING HAEMATOPOIETIC STEM CELL TRANSPLANTATION IN A LARGE COHORT OF PATIENTS FROM SWITZERLANDStéphane Buhler 1, Florence Studer-Bettens 1, Carole Dantin 1, Sylvie Ferrari-Lacraz 1, Yves Chalandon 1, Jean Villard 11Geneva University Hospitals, Geneva, Switzerland

O35 DISSECTING GENETIC CONTROL OF HLA-DPB1 EXPRESSION AND ITS RELATION TO STRUCTURAL MISMATCH MODELS IN HEMATOPOIETIC STEM CELL TRANSPLANTATIONThuja Meurer 1, Esteban Arrieta Bolaños 1, Maximilian Metzing 1, Mona Langer 2, Peter van Balen 3, Frederick Falkenburg 3, Dietrich W. Beelen 4, Peter A. Horn 2, Katharina Fleischhauer 1, Pietro Crivello 11Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany - 2Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany - 3Department of Hematology, Leiden University Medical Center, Leiden, Netherlands - 4Department of Bone Marrow Transplantation, West German Cancer Center, University Hospital Essen, Essen, Germany

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O36 HOW DONOR HLA MISMATCH, KIR-LIGAND MISMATCH AND NK CELL LICENSING MODELS AFFECT LEUKAEMIA RELAPSE IN HAEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTSElzbieta Graczyk-Pol 1, Marta Rogatko-Koros 1, Klaudia Nestorowicz 1, Slawomir Gwozdowicz 1, Renata Mika-Witkowska 1, Daria Pawliczak 1, Marta Zubala 1, Joanna Dziopa 1, Urszula Szlendak 1, Agnieszka Witkowska 1, Agnieszka Tomaszewska 1, Barbara Nasilowska-Adamska 1, Andrzej Szczepinski 1, Michal Wojcik 1, Kazimierz Halaburda 1, Jacek Nowak 11Institute of Hematology and Transfusion Medicine, Warsaw, Poland

O37 INVESTIGATING THE IMPACT OF PATIENTS’ NON-SHARED HLA-C ALLOTYPE EXPRESSION LEVELS IN A 9/10 SINGLE HLA-C MISMATCHED UNRELATED HSCT SETTING USING AN HLA-C EXPRESSION PROXY MODELChrysanthi Tsamadou 1, Daniel Furst 1, Dietger Niederwieser 2, Donald Bunjes 3, Christine Neuchel 1, Martin Gramatzki 4, Renate Arnold 5, Eva Wagner 6, Hermann Einsele 7, Hubert Schrezenmeier 1, Joannis Mytilineos 11German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 2University of Leipzig, Leipzig, Germany - 3University of Ulm, Ulm, Germany - 4University of Kiel, Kiel, Germany - 5Charité Campus Virchow Berlin, Ulm, Germany - 6Johannes Gutenberg-University Mainz, Mainz, Germany - 7University Hospital Würzburg, Würzburg, Germany

O38 MICRORNA EXPRESSION LEVELS IN CUTANEOUS ACUTE GRAFT-VERSUS HOST DISEASESadaf Atarod 1, Louis A. Bibby 2, Jean Norden 2, Anne Janin 3, Philippe Ratajczak 3, Clare Lendrem 2, Kim F. Pearce 2, Xiao-nong Wang 2, Steven O’Reilly 4, Jacob M. Van Laar 5, Matthew Collin 2, Anne M. Dickinson 2, Rachel E. Crossland 21Boston University and Boston Medical Center, Boston, United States of America - 2Newcastle University, Newcastle upon Tyne, United Kingdom (Great Britain) - 3Université Paris Diderot, Paris, France - 4Northumbria University, Newcastle upon Tyne, United Kingdom (Great Britain) - 5Utrecht University, Utrecht, Netherlands

O39 SINGLE HAPLOTYPE ADMIXTURE MODELS USING LARGE SCALE HLA GENOTYPES TO REPRODUCE HUMAN ADMIXTUREYoram Louzoun 1, Alexandra Litniski 1, Abeer Madbouly 2, Michael Halagan 2, Martin Maiers 31Bar Ilan University, Ramat Gan, Israel - 2NMDP, Minneapolis, United States of America - 3National Marrow Donor Program, Minneapolis, MN, United States of America

O40 QUANTITATIVE PCR-BASED CHIMERISM MONITORING IN BONE MARROW OR PERIPHERAL BLOOD TO PREDICT LEUKAEMIA RELAPSE IN HIGH-RISK PATIENTS: FINAL RESULTS OF THE KIM-PB PROSPECTIVE STUDYValentina Gambacorta 1, Riccardo Parolini 1, Elisabetta Xue 1, Raffaella Greco 1, Evelien Bouwmans 2, Cristina Toffalori 1, Fabio Giglio 1, Andrea Assanelli 1, Maria Teresa Lupo Stanghellini 1, Alessandro Ambrosi 3, Wietse Mulder 2, Consuelo Corti 1, Jacopo Peccatori 1, Fabio Ciceri 1, Luca Vago 11San Raffaele Scientific Institute, Milano, Italy - 2GenDx, Utrecht, Netherlands - 3University Vita-Salute San Raffaele, Milano, Italy

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Thursday 10 May 2018PARALLEL SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

14:40-16:10 Teaching Session 2 Clinical impact of de-novo HLA antibodies in solid organ

transplantation Antonina Piazza, David Turner

• The clinical relevance of de novo HLA antibodies in renal transplantation

Antonina Piazza• The clinical relevance of de novo HLA antibodies

in heart transplantation Martin Howell

• The clinical relevance of de novo HLA antibodies in pancreas and islet transplantation

David Turner• Q&A


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Thursday 10 May 2018PLENARY SESSION 2 AUDITORIUM - PALAZZO CINEMA

Solid organ transplantationChairpersons: Antonio Amoroso, Joannis Mytilineos

16:30-17:00 T regulatory cell based therapy in promoting tolerance solid organ transplantation

Giovanna Lombardi17:00-17:30 Desensitization in SOT Christophe M.F. Legendre17:30-18:00 Novel Biomarkers for allograft rejection in SOT Minnie M. Sarwal

PALAZZO DEL CASINÒ (3rd FLOOR)

18:00-20:00 Scientific Poster Reception (Sponsored by One Lambda and Lagitre, srl)

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Friday 11 May 2018PLENARY SESSION 3 AUDITORIUM - PALAZZO CINEMA

HSCT Current clinical perspectivesChairpersons: Luca Vago, Lotte Wieten

8:30-9:00 Haplo settings or impact of non shared haplotype on haplotransplant

Leonido Luznik9:00-9:30 Adoptive immunotherapies in HSCT Chiara Bonini9:30-10:00 Tregs in HSCT Silvia Gregori


PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

10:20-11:50 Oral Session 5: Solid Organ Transplantation

Chairpersons: Franco Papola, Dave L. RoelenO41 A NEW TOOL FOR QUANTIFICATION OF THE DONOR HLA-SPECIFIC MEMORY B CELL

REPERTOIRE IN IMMUNIZED PATIENTSGonca E. Karahan 1, Yvonne J.H. de Vaal 1, Juliette Krop 1, Caroline Wehmeier 1, Dave L. Roelen 1, Frans H.J. Claas 1, Sebastiaan Heidt 11Leiden University Medical Center, Leiden, Netherlands

O42 ROLE OF HLA-E-RESTRICTED CD8+ T CELLS IN TRANSPLANTATIONGabriella Pietra 1, Selene Ottonello 1, Irene Cossu 2, Lucy C. Sullivan 3, Michela Falco 4, Maria Christina Mingari 1, Lorenzo Moretta 51University of Genova, Genova, Italy - 2IRCCS Ospedale Policlinico San Martino, Genova, Italy - 3University of Melbourne, Melbourne, Australia - 4Laboratory of Clinical and Experimental Immunology, Giannina Gaslini Institute, Genova, Italy - 5Ospedale Pedriatico Bambino Gesù, Roma, Italy

FRID

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Friday 11 May 2018PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

O43 ENDOTHELIAL-EPITHELIAL-RELATED TRANSCRIPTIONAL LEVELS IN ACUTE REJECTION BIOPSIES OF KIDNEY TRANSPLANT RECIPIENTS ARE PREDICTIVE FOR A WORSE RESPONSE TO STEROID TREATMENTJianxin Yang 1, Marijke J. Spruyt-Gerritse 1, Darius Soonawala 1, Geert W. Haasnoot 1, Hans W. de Fijter 1, Marlies E.J. Reinders 1, Marian C. Clahsen 2, Frans H.J. Claas 1, Michael Eikmans 11Leiden University Medical Center, Leiden, Netherlands - 2Erasmus Medical Center, Rotterdam, Netherlands

O44 KIDNEY TRANSPLANTED PATIENTS WITH OPERATIONAL TOLERANCE HAVE INCREASED FREQUENCIES OF CD19+CD1D+CD5+ SUPPRESSOR B CELLS AND HAVE A POSITIVE CORRELATION WITH THE PERCENTAGE OF TOTAL B CELLSCristian M. Alvarez 1, Christian Morath 2, Marlon Castrillon 1, Daniel Alzate 1, Gerhard Opelz 2, Martin Zeier 2, Caner Süsal 21Universidad de Antioquia, Medellin, Colombia - 2University of Heidelberg, Heidelberg, Germany

O45 HLA EPITOPE MATCHING OF KIDNEY TRANSPLANTS PREDICTS ANTIBODY- AND CELL-MEDIATED REJECTIONNils Lachmann 1, Oliver Staeck 1, Matthias Niemann 2, Klemens Budde 1, E. Spierings 3, Constanze Schönemann 11Charité - Universitätsmedizin Berlin, Berlin, Germany - 2PIRCHE AG, Berlin, Germany - 3University Medical Center Utrecht, Utrecht, Netherlands

O46 STUDY OF IMMUNOLOGICAL AND IMMUNOGENIC RISK FACTORS FOR BKV REPLICATION AFTER RENAL TRANSPLANTATIONSnezhina Mihaylova 1, Atanaska Georgieva 2, Yana Krasteva 2, Anastasya Mihaylova 1, Tsvetelin Lukanov 2, Valentina Atanasova 2, Luisa Hristova 2, Emil Paskalev 1, Elissaveta Naumova 11Medical University Sofia, University Hospital Alexandrovska, Sofia, Bulgaria - 2University Hospital Alexandrovska, Sofia, Bulgaria

O47 DIFFERENCES FOR T-CELLS SUBTYPES IN ASPIRATION BIOPSIES OF KIDNEY TRANSPLANT PATIENTS UNDER POLYCLONAL AND MONOCLONAL IMMUNOSUPPRESSIVE TREATMENTSMaria Paula DP. Xavier 1, Maria Conceição Magalhães 2, Susana Sampaio-Norton 3, Tiago Guimarães 2, José Gerardo Oliveira 41Instituto Português do Sangue e da Transplantação, Porto, Portugal - 2Centro Hospitalar S. João, Serviço Patologia Clínica, Porto, Portugal - 3Hospital S. João, Serviço Nefrologia, Porto, Portugal - 4Faculdade Medicina Porto, Hospital S. João, Porto, Portugal

O48 IMPACT OF HLA-E*01:03 ALLELE CARRIER STATUS AND NKG2C ALLELE DELETION ON THE RISK OF CMV INFECTION AFTER RENAL TRANSPLANTATIONHana Guberina 1, Fabiola da Silva Nardi 1, Rafael Tomoya Michita 1, Sebastian Dolff 1, Anja Gäckler 1, Falko M. Heinemann 1, Benjamin Wilde 1, Mirko Trilling 1, Peter A. Horn 1, Andreas Kribben 1, Oliver Witzke 1, Vera Rebmann 11University Hospital Essen, University Duisburg-Essen, Essen, Germany

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10:20-11:50 Oral Session 6: NK and Miscellaneous

Chairpersons: Benedetta Mazzi, Caner SüsalO49 IMPACT OF KIR ALLELE POLYMORPHISM ON THE STRUCTURE AND THE FUNCTION OF

KIR2D NK CELL REPERTOIREKatia Gagne 1, Bercelin Maniagou 2, Léa Dubreuil 2, Gaelle David 2, Nolwenn Legrand 2, Catherine Willem 2, Christelle Retiere 21Blood Bank EFS; CRCINA; Labex Transplantex, Nantes, France - 2Blood Bank EFS; CRCINA; Nantes, France

O50 THE ROLE OF T CELL RECEPTOR CROSS-REACTIVITY IN HUMAN DISEASESNicole Mifsud 1, Louise Rowntree 1, Lloyd D’Orsogna 2, Heleen van den Heuvel 3, Frans Claas 4, Patricia Illing 1, Stephanie Gras 1, Tom Kotsimbos 5, Anthony Purcell 11Monash University, Clayton, Australia - 2Fiona Stanley Hospital, Perth, Australia - 3Leiden University Medical Centre/Monash University, Leiden, Netherlands - 4Leiden University Medical Centre, Leiden, Netherlands - 5The Alfred Hospital/Monash University, Melbourne, Australia

O51 THE GENETIC IMBALANCE AMONG HLA LIGANDS FOR INHIBITORY KIR3D RECEPTORS IN KAWASAKI CHILDREN: CLUES FOR ETIOPATHOGENESISCristina Capittini 1, Annalisa De Silvestri 1, Grazia Bossi 1, Savina Mannarino 1, Annamaria A. Pasi 1, Carmine Tinelli 1, Miryam Martinetti 1, Giacomo Emmi 21IRCCS Policlinico San Matteo Foundation, Pavia, Italy - 2Careggi University Hospital, University of Florence, Florence, Italy

O52 KIR HAPLOTYPES DEFINED BY THEIR TRANSCRIPTOMESJesse Bruijnesteijn 1, Marit K. H. Van der Wiel 1, Wendy Swelsen 2, Nel Otting 3, Annemiek J. M. de Vos-Rouweler 3, Diënne Elferink 4, Gaby G.M. Doxiadis 3, Neubury M. Lardy 2, Natasja G. De Groot 3, Ronald E. Bontrop 31BPRC, Rijswijk, Netherlands - 2Sanquin, Amsterdam, Netherlands - 3Biomedical Primate Research Centre, Rijswijk, Netherlands - 4LUMC, Leiden, Netherlands

O53 FUNCTIONAL ANALYSIS OF SOLUBLE NKG2D LIGAND EXPRESSION IN UMBILICAL CORD BLOOD PLASMA REVEALS ACTIVATING POTENTIAL OF SOLUBLE MICA-129VAL VARIANTSSteven T. Cox 1, Robert Danby 1, Diana Hernandez 1, Alejandro Madrigal 1, Aurore Saudemont 11Anthony Nolan Research Institute, London, United Kingdom (Great Britain)

O54 VITREOUS CRYOPRESERVATION OF HLA-MATCHED VASCULAR GRAFTS UTILIZING THE DECELLULARIZED HUMAN UMBILICAL ARTERYPanagiotis Mallis 1, Efstathios Michalopoulos 1, Michalis Katsimpoulas 2, Amalia Dinou 1, Aggeliki Papapanagiotou 3, Maria Spyropoulou-Vlachou 4, Catherine Stavropoulos-Giokas 11Hellenic Cord Blood Bank-Biomedical Research Foundation Of the Academy of Athens, Athens, Greece - 2Biomedical Research Foundation Of the Academy of Athens, Athens, Greece - 3National and Kapodistrian University of Athens, Athens, Greece - 4Alexandra General Hospital of Athens, Athens, Greece

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O55 GENE EXPRESSION PROFILING REVEALS THE MOLECULAR SIGNATURE OF SEVERE CARBAMAZEPINE-INDUCED HYPERSENSITIVITY REACTIONSNicole Mifsud 1, Alison Anderson 2, Patricia Illing 1, Patrick Kwan 2, Anthony Purcell 11Monash University, Clayton, Australia - 2Royal Melbourne Hospital/University of Melbourne, Parkville, Australia

O56 HLA-G SELECTS PEPTIDES TISSUE SPECIFIC AND DISPLAYS EXCEPTIONAL TARGETS FOR IMMUNE EVASIONAlexander A. Celik 1, Gwendolin S. Simper 1, Trevor Huyton 2, Wiebke Hiemisch 1, Rainer Blasczyk 1, Christina Bade-Doeding 11Hannover Medical School, Hannover, Germany - 2Max Planck Institute, Göttingen, Germany

PARALLEL SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

10:20-11:50 Teaching Session 3 Tools for a successful HSCT: evaluation of HLA allele

frequencies, anti-HLA antibodies, structural and expression models for permissive mismatches

Marcelo A. Fernández-Viña, Katharina Fleischhauer

• Allele and haplotype frequencies: How variation affects donor searches

• Anti-HLA antibodies: Role of DSA in HLA mismatched transplantation

• Coding and non-coding HLA variation: Relationship between T-cell epitopes and HLA expression levels for permissive mismatches in HSCT

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Friday 11 May 2018LUNCHEON SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

12:00-13:00 Luncheon Session - Bag Health CareFirst experiences with the HISTO SPOT® HLA AB test for automated antibody diagnosticsJohn Smith, PhD, FRCPathHCS Consultant Head of Tissue Typing Service, Heart Science Centre, Harefield Hospital, Harefield, UKEvaluation of the HISTO SPOT® HLA AB test in comparison to a Luminex SA TestIng. Murielle VerboomMedizinische Hochschule Hannover, Institute of Transfusion Medicine, Transplantation Immunology, Hannover, Germany


12:00-13:00 Luncheon Session - One LambdaDSA Flow Cytometry Crossmatching… The New FrontierCathi Murphey, Half, Ph.DDirector, Histocompatibility and Immunogenetics LaboratorySouthwest Immunodiagnostics, IncSan Antonio, Texas

13:00-13:30 Lunch13:30-14:30 Luncheon Session - One Lambda

LinkSēq™ SABR HLA Typing Kit resolution and HLA specific antibodies identification using the single antigen technologyJulie JouffreyMedical EngineerLaboratoire d’Immunologie et HistocompatibilitéHôpital Saint LouisParis, France

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Friday 11 May 2018LUNCHEON SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR)

13:30-14:30 Luncheon Session - HistogeneticsNew Horizons in HLA Typing and Haplotyping: Revolution in HLA GenomicsNezih Cereb, MD - CEO and Co-Founder Histogenetics

SPECIAL JOINT SESSION AUDITORIUM - PALAZZO CINEMA

WMDA and EFIChairpersons: Lydia Foeken, Elissaveta Naumova, Nicoletta Sacchi

14:40-15:10 Past, Present and Future of unrelated Donor registries Lydia Foeken15:10-15:40 Pharma-economics of CB banking in the haplo era Sergio Luis Querol-Giner15:40-16:10 How to choose the best unrelated HSC donor? Carolyn Katovich Hurley

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14:40-16:10 Oral Session 7: Reproduction, Autoimmunity, Infection & Cancer

Chairpersons: Andrea Bontadini, Antonio MartinhoO57 AN ALTERNATIVELY SPLICED ISOFORM OF THE HUMAN LEUKOCYTE ANTIGEN-DR ALPHA

CHAIN IS ASSOCIATED WITH THE MULTIPLE SCLEROSIS RISK ALLELE HLA-DRB1*15:01Vincent Damotte 1, Alessandro Didonna 1, Maneesh K. Misra 1, Noriko Isobe 1, Ravi Dandekar 1, Ashley H. Beecham 2, Stacy Cailler 1, Adam Santaniello 1, Jacob L. McCauley 2, Steven L. Hauser 1, Jorge R. Oksenberg 1, Jill A. Hollenbach 11University of California, San Francisco, San Francisco, United States of America - 2University of Miami, Miami, United States of America

O58 HELLP SYNDROME IS ASSOCIATED WITH MHC GENES IN A FINNISH POPULATIONA. Inkeri Lokki 1, Jenni Heikkinen-Eloranta 2, Juha Sinisalo 2, Hannele Laivuori 3, Marja-Liisa Lokki 11University of Helsinki, Helsinki, Finland - 2University of Helsinki and Helsinki University Hospital, Helsinki, Finland - 3University of Tampere, Tampere, Finland

O59 EXPRESSION QTLs WITH OPPOSING EFFECTS ON HLA-DR AND -DQ GENES ARE ASSOCIATED WITH AUTOIMMUNE DISORDERS: EVIDENCE FOR MIXED ISOTYPE HETERODIMER FORMATION?Sandeep K. Singh 1, Johannes Dapprich 2, Jacob L. McCauley 3, Mehmet Tevfik Dorak 41Ohio State University, Columbus, OH, United States of America - 2Generation Biotech, Lawrenceville, NJ, United States of America - 3University of Miami, John P. Hussman Institute for Human Genomics, Miami, FL, United States of America - 4Kingston University London, Kingston, United Kingdom (Great Britain)

O60 HLA-DRB1*09:01 IS ASSOCIATED WITH A SEVERE ASTHMA OUTCOME IN THE CONSORTIUM ON ASTHMA AMONG AFRICAN-ANCESTRY POPULATIONS IN THE AMERICAS (CAAPA)Nicolas Vince 1, Sophie Limou 2, Michelle Daya 3, Nicholas Rafaels 3, Jill Hollenbach 4, Antoine Lizée 4, Estelle Geffard 1, Alexandre Walencik 5, Maria Pino-Yanes 6, Steven Salzberg 7, Daehwan Kim 7, Harold Watson 8, Leslie Lange 3, James Wilson 9, Terri Beaty 7, Margaret Taub 7, Ingo Ruczinski 7, Rasika Mathias 7, (CAAPA) Consortium on Asthma among African-ancestry Populations in the Americas 7, Kathleen Barnes 3, Dara Torgerson 4, Pierre-Antoine Gourraud 10

1INSERM, Université de Nantes, Nantes, France - 2INSERM, Université de Nantes, Ecole Centrale de Nantes, Nantes, France - 3University of Colorado, Aurora, CO, United States of America - 4University of California San Francisco, San Francisco, CA, United States of America - 5EFS Centre - Pays de la Loire, Nantes, France - 6Universidad de La Laguna, Santa Cruz de Tenerife, Spain - 7Johns Hopkins University, Baltimore, MD, United States of America - 8The University of the West Indies, Queen Elizabeth Hospital, Bridgetown, Barbados - 9University of Mississippi Medical Center, Jackson, MS, United States of America - 10INSERM, Université de Nantes, CHU de Nantes, Nantes, France

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O61 NEXT GENERATION SEQUENCING OF BTNL2 REVEALS NOVEL ASSOCIATIONS WITH ACUTE CORONARY SYNDROME IN FINNISH POPULATIONMarja Marchesani 1, Juha Sinisalo 2, Veikko Salomaa 3, Markus Perola 4, Markku S. Nieminen 5, Steven J. Mack 6, Marja-Liisa Lokki 11University of Helsinki, Helsinki, Finland - 2Helsinki University Hospital, Helsinki, Finland - 3National Institute for Health and Welfare, Helsinki, Finland - 4National Institute for Health and Welfare (THL), Helsinki, Finland - 5Helsinki University Central Hospital, Helsinki, Finland - 6Children’s Hospital Oakland Research Institute, United States of America

O62 MACROPHAGE MIGRATION INHIBITORY FACTOR AND D-DOPACHROME TAUTOMERASE ARE POTENTIAL DISEASE SEVERITY MODIFIERS IN MALE MULTIPLE SCLEROSIS SUBJECTSGil Benedek 1, Halina Offner 2, Jorge R. Oksenberg 3, Dennis Bourdette 2, Richard Bucala 4, Arthur A. Vandenbark 21Hadassah Medical Center, Jerusalem, Israel - 2Oregon Health & Science University, Portland, Oregon, United States of America - 3University of California, San Francisco, San Francisco, United States of America - 4Yale School of Medicine, New Haven, United States of America

O63 FUNCTIONAL ANNOTATION OF THE CLUSTER OF SCHIZOPHRENIA RISK MARKERS IN THE EXTENDED HLA CLASS I REGIONSandeep K. Singh 1, Johannes Dapprich 2, Mehmet Tevfik Dorak 31Ohio State University, Columbus, OH, United States of America - 2Generation Biotech, Lawrenceville, NJ, United States of America - 3Kingston University London, Kingston, United Kingdom (Great Britain)

O64 ASSOCIATION OF MICA POLYMORPHISM WITH MICA SERUM LEVELS AND CLINICAL OUTCOME OF ANTI-TNF THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITISMilena Iwaszko 1, Jerzy Świerkot 2, Marta Dratwa 1, Barbara Wysoczańska 1, Lucyna Korman 2, Katarzyna Kolossa 3, Sławomir Jeka 3, Piotr Wiland 2, Katarzyna Bogunia-Kubik 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Wrocław Medical University, Wrocław, Poland - 3Hospital University Number 2 Jana Biziela, Bydgoszcz, Poland

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Friday 11 May 2018PARALLEL SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

14:40-16:10 Teaching Session 4 How to prepare for an inspection: demonstrating how quality

standards are met Andrea Harmer, Luca MascarettiPresenters: Milena Ivanova, Christien Voorter

• Preparing for Packet A and Packet C inspection• Common deficiencies• How to meet molecular testing and main quality management

standards• Use of the accreditation software• Q&A and best practices


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Friday 11 May 2018PLENARY SESSION 4 AUDITORIUM - PALAZZO CINEMA

Immunogenetics beyond HLAChairpersons: Marcel G.J. Tilanus, John Trowsdale

16:30-17:00 Immunogenetics in autoimmunity Francesco Cucca17:00-17:30 Exploiting targeted (EPI) genome editing for therapeutic

applications Angelo Lombardo17:30-18:00 GWAS in multiple sclerosis Stephen James Sawcer


18:00-19:30 EFI General Assembly

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Saturday 12 May 2018AUDITORIUM - PALAZZO CINEMA

8:30-10:00 Best Abstract SessionChairpersons: Katharina Fleischhauer, Luca MascarettiO1 THE ENIGMA OF HLA-MEDIATED ADVERSE DRUG REACTIONS: EPOXIDE BUT NOT

CARBAMAZEPINE INDUCES THE BINDING OF HAPTENATED PEPTIDES TO HLA-B*15:02Gwendolin S. Simper 1, Alexander A. Celik 1, Gia-Gia T. Hò1, Trevor Huyton 2, Joachim Kuhn 3, Rainer Blasczyk 1, Christina Bade-Doeding 11Hannover Medical School, Hannover, Germany - 2Max Planck Institute, Göttingen, Germany - 3Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany

O2 IMMUNITY ON A KNIFES EDGE: SELF/NON-SELF DISCRIMINATION AND THE CO-EXPRESSION OF NATURAL KILLER CELL RECEPTORS FINELY TUNES T CELL RECEPTOR AFFINITY AND FUNCTIONLucy C. Sullivan 1, Christopher M. Harpur 1, Thi H.O. Nguyen 1, Abbie R. Kanagarajah1, Jacqueline M.L. Widjaja 1, Gabriella Pietra 2, Katherine Kedzierska 1, Karl-Johan Malmberg 3, Andrew G. Brooks 11University of Melbourne, Melbourne, Australia - 2University of Genoa, Genoa, Italy - 3Institute for Cancer Research, Oslo University Hospital, Oslo, Norway

O3 INVISIBLE ORGANS MADE BY GENETIC ENGINEERING TO TURN OFF MHC PRIOR TO ALLOGENEIC TRANSPLANTATION PREVENT A PRO-INFLAMMATORY CYTOKINE RESPONSE IN THE RECIPIENTConstanca Figueiredo 1, Marco Carvalho-Oliveira 1, Chen Chen-Wacker 1, Klaus Höffler 1, Marc Kühnel 1, Katharina Jansson 1, Axel Haverich 1, Gregor Warnecke 1, Rainer Blasczyk 11Hannover Medical School, Hannover, Germany

O4 THE ALLOTYPIC ARCHITECTURE OF HLA-B57 ALLOTYPES ALTERS PEPTIDE CONFORMATION TO REGULATE INHIBITION OF NK CELL ACTIVATION THROUGH KIR3DL1Andrew G. Brooks 1, Philippa M. Saunders 1, Philip Pymm 2, Jacqueline ML. Widjaja 1, Jie Lin 1, Jamie Rossjohn 2, Julian P. Vivian 21Peter Doherty Institute, University of Melbourne, Melbourne, Australia - 2Monash University, Clayton, Australia

O5 EPIGENOME-WIDE ASSOCIATION STUDY REVEALS IMMUNOGENETIC TARGETS OF DNA METHYLATION MODIFICATION BY HIV-1Kevin Hoang 1, George Nelson 2, Elizabeth Binns-Roemer 2, Nicolas Vince 1, Pierre-Antoine Gourraud 3, James J. Goedert 4, Cheryl Winkler 2, Sophie Limou 51INSERM, Université de Nantes, Nantes, France - 2Frederick National Laboratory, Frederick, MD, United States of America - 3INSERM, Université de Nantes, CHU de Nantes, Nantes, France - 4NIH/NCI, Bethesda, MD, United States of America - 5INSERM, Université de Nantes, Ecole Centrale de Nantes, Nantes, France

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Saturday 12 May 2018AUDITORIUM - PALAZZO CINEMA

O6 EXPLOITING CUTTING-EDGE TECHNOLOGIES TO ANALYZE LOSS OF HLA IN A GLOBAL MULTICENTRIC COHORT OF POST-TRANSPLANTATION RELAPSES: PRELIMINARY RESULTS FROM THE HLA LOSS COLLABORATIVE STUDY Luca Vago 1, Cristina Toffalori 1, Ahci Müberra 2, Vinzenz Lange 3, Kathrin Lange 3, Sonia Todaro 1, Karin Stempelmann 2, Andreas Heinold 2, Friedrich Stölzel 4, Miguel Waterhouse 5, Rainer Claus 5, Ketevan Gendzekhadze 6, Masahiro Onozawa 7, Raynier Devillier 8, Ruoping Tang 9, Maayan Ulman 10, Dejan Lazarevic 1, Maria Teresa Lupo Stanghellini 1, Jacopo Peccatori 1, Nina K. Steckel 2, Peter A. Horn 2, Alessandra Picardi 11, Sara Manetta 12, Jose L. Pinana 13, Jaimie Sanz 13, Brian Schaffer 14, William Arcese 11, Guillermo Sanz 13, Benedetto Bruno 12, Massimo Pini 15, Guido Kobbe 16, Katharine C. Hsu 14, Monzr Al Malki 6, Takanori Teshima 7, Nicolaus Kroeger 17, Jurgen Finke 5, Arnon Nagler 10, Didier Blaise 8, Mohamad Mohty 9, Martin Bornhauser 4, Dietrich W. Beelen 2, Alexander Schmidt 3, Fabio Ciceri 1, Katharina Fleischhauer 21San Raffaele Scientific Institute, Milano, Italy - 2Essen University Hospital, Essen, Germany - 3DKMS Life Science Lab, Dresden, Germany - 4Technical University Dresden, Medical Clinic and Policlinic I, Dresden, Germany - 5University Medical Center Freiburg, Freiburg, Germany - 6City of Hope National Medical Center, Duarte, CA, United States of America - 7Hokkaido University, Faculty of Medicine, Sapporo, Japan - 8Institut Paoli-Calmettes, Marseille, France - 9Hopital Saint Antoine AP-HP, Paris, France - 10Chaim Sheba Medical Center, Tel-Hashomer and Tel-Aviv University, Tel Aviv, Israel - 11Tor Vergata University of Rome - Regional Transplant Center of Lazio, Roma, Italy - 12A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy - 13Hospital Universitari i Politècnic La Fe, Valencia, Spain - 14Memorial Sloan Kettering Cancer Center, New York, NY, United States of America - 15A.O. SS Antonio e Biagio e C. Arrigo, Alessandria, Italy - 16Heinrich-Heine University, Dusseldorf, Germany - 17University Hospital Eppendorf, Hamburg, Germany

O7 UNRAVELLING DYNAMIC CHANGES IN THE MATERNAL IMMUNE COMPARTMENT AT THE MATERNAL-FETAL INTERFACE DURING PREGNANCY BY MASS CYTOMETRYAnita van der Zwan 1, Vincent van Unen 1, Thomas Höllt 2, Hanneke J.M. Kapsenberg 1, Marie-Louise P. van der Hoorn 1, Merve Uyar-Mercankaya 1, Susana M. Chuva de Sousa Lopes 1, Frits Koning 1, Frans H.J. Claas 1, Sebastiaan Heidt 11Leiden University Medical Center, Leiden, Netherlands - 2Delft University of Technology, Delft, Netherlands

O8 LOSS OF HLA-A IN ACUTE MYELOID LEUKEMIA TRANSMITTED BY THE DONOR TO LIVER AND KIDNEY GRAFT RECIPIENTSLuigi Marchionni 1, Anna Serra 2, Federico Genzano Besso 3, Silvia Deaglio 2, Piero Stratta 4, Monica Berrino 3, Francisco Lobo Pereira 1, Aleksei Stupniko 1, Gianluca Gaidano 4, Benedetto Bruno 2, Giuseppe Saglio 2, Antonio Amoroso 41Johns Hopkins University, Baltimore, United States of America - 2University of Turin, Turin, Italy - 3Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Presidio Molinette, Torino, Italy - 4University of Eastern Piedomont, Novara, Italy

10:00-10:30 17th and 18th IHW reports The 17th International HLA & Immunogenetics Workshop 2017 Marcelo A. Fernández-Viña The 18th International HLA & Immunogenetics Workshop 2021 Eric Spierings

10:30-10:50 Coffee break

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Saturday 12 May 2018PLENARY SESSION 5 AUDITORIUM - PALAZZO CINEMA

New frontiers in immunogeneticsChairpersons: Elissaveta Naumova, David Turner

10:50-11:20 Single cell technologies Ido Amit11:20-11:50 Immunopeptidome Markus Löffler11:50-12:20 Neoantigens in cancer immunotherapy Derin Keskin

CLOSING CEREMONY AUDITORIUM - PALAZZO CINEMAChairpersons: Valeria Miotti, Elissaveta Naumova

12:20-12:50 Closing LectureChairpersons: Carlo Carcassi, Valeria Miotti Leonardo da Vinci: the prototype of Art & Science man Pietro Cesare Marani12.50-13.00 Jon van Rood Award and Best Abstract Awards Committee Chair: Frans H.J. Claas13.00-13.10 Best Poster Awards Committee: Marco Andreani, Carlo Carcassi,

Luca Mascaretti, Sandra Tafulo, Hien Tran13.10-13.20 EFI 2019, Lisbon Antonio Martinho

13.20-13.30 Closing Remarks

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POSTER PRESENTATIONSSOLID ORGAN TRANSPLANTATIONP1 INTRA-GRAFT DETECTION OF ANTI-HLA ANTIBODIES AND TRANSPLANT FAILURE: A

REPORT OF FOUR CASESElena Longhi 1, Angela Nocco 1, Miriam Ramondetta 1, Viviana Sioli 2, Annalisa Innocente 2, Loretta Crespiatico 2, Mario Macchiagodena 2, Denise Bertola 2, Caterina Brambilla 2, Nicoletta Cagni 2, Massimo Cardillo 31Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy - 2IRCCS Maggiore Policlinico Hospital, Milano, Italy - 3Fondazione IRCCS Ca’ Granda- Ospedale Maggiore Policlinico, Milan, Italy

P2 IMPACT OF FC-GAMMA RECEPTORS IIIA [158F/V] POLYMORPHISMS ON CHRONIC LUNG ALLOGRAFT DYSFUNCTION (CLAD) AND PATIENTS SURVIVAL AFTER LUNG TRANSPLANTATIONChristophe Picard 1, Julie Di Cristofaro 1, Pascale Paul 2, Agnes Basire 3, Anderson Loundou 4, Mattieu Pelardy 3 Luc Lyonnet 5, Coralie Frassati 3, Pascal Thomas 6 Carine Gomez 6 Martine Reynaud-Gaubert 61UMR7268 AMU CNRS EFS, MARSEILLE, France - 2INSERM 1076, Aix Marseille Université, Assistance Publique Hopitaux de Marseille, Marseille, France - 3EFS PACAC, Marseille, France - 4University hospital Marseille, Marseille, France - 5Assistance Publique hopitaux de Marseille, Hematology Unit, Marseille, France - 6APHM-Hôpital Nord, Marseille, France

P3 APPLICATION OF THE SINGLE REGIONAL LIST FOR KIDNEY TRANSPLANTATION IN SICILY. CRITICALITY AND ADVANTAGESSerena Mistretta 1, Rosalba Bavetta 1, Floriana Bruno 1, Giuseppe Davì 1, Valentina Cappuzzo 1, Francesco Ingrassia 1, Maria Igea Vega 1, Maria Blando 1, Bruna Piazza 2, Raimondo Marcenò 11Lab. Regionale di Tipizzazione Tessutale ed Immunologia dei Trapianti, Palermo, Italy - 2Centro Regionale Trapianti (CRT) Sicilia, Palermo, Italy

P4 KIDNEY TRANSPLANT FOR HIGHLY SENSITISED PATIENTS ON THE SICILIAN WAITING LIST: REPORT ON THE FIRST TRANSPLANTED PATIENTSerena Mistretta 1, Rosalba Bavetta 1, Floriana Bruno 1, Giuseppe Davì 1, Valentina Cappuzzo 1, Francesco Ingrassia 1, Maria Igea Vega 1, Maria Blando 1, Valentina Vinti 2, Antonio Amato 2, Flavia Caputo 2, Raimondo Marcenò1

1Lab. Regionale di Tipizzazione Tessutale ed Immunologia dei Trapianti, Palermo, Italy - 2Nefrologia con Trapianto, Palermo, Italy

P5 OMISSION OF THE PROSPECTIVE CROSSMATCH IN DECEASED DONOR KIDNEY TRANSPLANTATION AND INCIDENCE OF EARLY AMRDavid M. Turner 1, Richard Battle 1, Angus Turnbull 2, Lorna Henderson 21Scottish National Blood Transfusion Service, Edinburgh, United Kingdom (Great Britain) - 2Transplant Unit, Edinburgh, United Kingdom (Great Britain)

P6 BAFF RS12874404 SNP DOES NOT INFLUENCE ANTI-HLA ANTIBODY PRODUCTION IN KIDNEY RECIPIENTSSilvia Alizzi 1, Pamela M. Moschini 1, Maristella Pitzalis 2, Maristella Steri 2, Cristiana Caorsi 3, Claudia Maria Rosso 4, Silvia Deaglio 5, Francesco Cucca 2, Antonio Amoroso 51Città della Salute e della Scienza Hospital, Torino, Italy - 2Consiglio Nazionale delle Ricerche, Cagliari, Italy - 3AOU Città della Salute e della Scienza di Torino, Torino, Italy - 4Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Presidio Molinette, Torino, Italy - 5University of Turin, Torino, Italy



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P7 DETERMINATION OF LEUKOCYTE ANTIBODIES IN PATIENTS WAITING FOR KIDNEY TRANSPLANTATION IN THE REPUBLIC OF KAZAKHSTANAida Turganbekova 1, Zhandos Burkitbaev 1, Saniya Abdrakhmanova 1, Indira Ramilyeva 1, Dana Baimukasheva 1, Zhazira Saduakas 1, Perizat Zhunus 11Republic scientific and production center of transfusiology, Astana, Kazakhstan

P8 THE IMPACT OF DE NOVO DONOR SPECIFIC ANTIBODIES AND HLA HISTOCOMPATIBILITY IN LONGTERM KIDNEY TRANSPLANTATION OUTCOME (UP TO 27 YEARS)Asimina Fylaktou 1, Efstratios Kasimatis 2, Theodoros Karampatakis 1, Maria Schoina 2, Aikaterini Anastasiou 1, Anna Boukla 1, Vasiliki Nikolaidou 1, Marianthi Papachristou 1, Theodoros Chronis 1, Aikaterini Papagianni 21National Peripheral Histocompatibility Center, Hippokration General Hospital, Thessaloniki, Greece - 2Kidney Department,Hippokration General Hospital, Thessaloniki, Greece

P9 DONOR SPECIFIC ANTI-HLA IGA ANTIBODIES AND GRAFT SURVIVAL AFTER KIDNEY TRANSPLANTATIONMarie-Luise Arnold 1, Christian Bach 2, Falko M. Heinemann 3, Andrea Dick 4, Bernd M. Spriewald 21Institute for Clinical Immunology, Department of Internal Medicine 3, Rheumatology and Immunology, Erlangen, Germany - 2Institute for Clinical Immunology, Department of Internal Medicine 5, Hematology and Oncology, Erlangen, Germany - 3Intitute for Transfusion Medicine, University Hospital Duisburg-Essen, Essen, Germany - 4Laboratory of Immunogenetics, Ludwig Maximilians University, Munich, Germany

P10 RITUXIMAB INTERFERENCE IN B-CELL CROSSMATCH: A PROBLEM SOLVEDBeatrice Bardy 1, Paolo Malvezzi 2, Lionel Rostaing 2, Dominique Masson 11EFS Rhone Alpes, La Tronche, France - 2CHU Grenoble Alpes, Grenoble, France

P11 ANTIBODY-MEDIATED REJECTION AFTER LIVER TRANSPLANTATION - SELECTED IMMUNOLOGICAL PARAMETERSAntonij Slavcev 1, Zuzana Sekerkova 1, Barbora Kovandova 1, Eva Honsova 1, Sarka Valhova 1, Pavel Trunecka 11IKEM, Prague, Czech Republic

P12 HIGHLY-SENSITIZED PATIENTS: MORE THAN ANTI-HLA ANTIBODIESLaura Riesco 1, Juan Irure 1, Emilio Rodrigo 1, Juan Calos Ruiz-San Millán 1, Marcos López-Hoyos 1, David San Segundo 11Marques de Valdecilla Universitary Hospital-IDIVAL, Santander, Spain

P13 EFFICIENCY OF DONOR EXCHANGE PROGRAM AT KING FAISAL SPECIALIST HOSPITAL JEDDAHAshraf Dada 1, Nabeela Al Baz 1, Hamad Bokhari 11Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia

P14 CLINICAL RELEVANCE OF COMPLEMENT-DEPENDENT CYTOTOXICITY AS A SUPPORTING ASSAY IN THE KIDNEY PAIR EXCHANGE SETTINGAshraf Dada 1, Osama Al Suraihi 1, Nabeela Al Baz 1, Ahmad Bokhari 11Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia

P15 EDTA TREATMENT WITH NORMAL GOAT SERUM (GS) BLOCKING REMOVES DR4/DR16 BUT NOT DP1/DP5 FALSE POSITIVE PATTERNS ON SINGLE ANTIGEN BEAD (SAB) HLA CLASS II ANTIBODY TESTINGKristina A. Davis 1, Maria Ramirez 1, Timothy Williams 1, Lena Kleyman 1, Gregory Simmons 1, Debra Schauss 1, Abdul Abdulle 1, Nell Field 1, Samantha Fogel 1, Thomas Franks 1, Kelsey Makushik 1, Andrea Parkinson 1, Cory Peitsch 1, Cynthia Schall 1, Omar Moussa 11University of Michigan, Ann Arbor, United States of America






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P16 PATIENTS AWAITING KIDNEY TRANSPLANTATION ARE MORE FREQUENTLY CARRIERS OF THE RS763780 488G ALLELE THAT IS ASSOCIATED WITH HIGHER IL-17F SERUM LEVELSMalgorzata Kaminska 1, Wanda Niepieklo-Miniewska 1, Artur Nieszporek 1, Katarzyna Gebura 1, Katarzyna Bogunia-Kubik 11Hirszfeld Institute of Immunology and Experimental Therapy, Wroclaw, Poland

P17 COMPARISON OF VIRTUAL AND CDC, FLOW, LUMINEX CROSS MATCH METHODSDerya Gulec 1, Tulay Kilicaslan Ayna 1, Asli Kocyigit Ozkizilcik 1, Asli Eldem 1, Burcu Cerci Gurbuz 1, Mustafa Soyoz 11Tepecik Training and Research Hospital, Izmir, Turkey

P18 IN VITRO TGF-Β SECRETION CAPACITY OF STIMULATED PERIPHERAL BLOOD CELLS CORRELATES WITH THE OCCURRENCE OF OPPORTUNISTIC INFECTION IN LIVER AND KIDNEY TRANSPLANTATIONFrancisco Boix 1, Gema Gonzalez-Martinez 1, Rafael Alfaro 1, Jose Antonio Galian 1, Isabel Legaz 2, Maria R. Moya-Quiles 1, Alfredo Minguela 1, Jose A. Pons 1, Santiago Llorente 1, Manuel Muro 11Clinic University Hospital Virgen Arrixaca, Murcia, Spain - 2University of Murcia, Murcia, Spain

P19 COMPARING INFERENCES DRAWN FROM INTERMEDIATE HLA TYPING TO HIGH RESOLUTION TYPING RESULTS - COULD IT BE AN INTERIM SOLUTION? A STUDY FROM A TERTIARY CARE MEDICAL INSTITUTION IN INDIASam A. Doss R 1, Siddharth Mittal 2, Mary P. Chacko 2, Dolly Daniel 21Christian Medical College & Hospital, Vellore, India - 2Christian Medical College, Vellore, India

P20 UNEXPECTED FLOW CYTOMETRY CROSSMATCH REACTIVITY IN PATIENTS AWAITING KIDNEY TRANSPLANTAnastasiya Mihaylova 1, Petiya Yankova 1, Anzhela Antonova 2, Nevena Gesheva 2, Valentina Atanasova 2, Milena Ivanova-Shivarova 1, Elissaveta Naumova 11University Hospital Alexandrovska, Medical University, Sofia, Bulgaria - 2University Hospital Alexandrovska, Sofia, Bulgaria

P21 ANALYSIS OF HLA ALLOREACTIVITY BASED ON PREDICTION OF HLA-DRB1 RESTRICTED T CELL EPITOPESMiriam Vilches-Moreno1, Cristina Abad-Molina 2, Antonio Nieto 11Hospital Puerta del Mar, Cádiz, Spain - 2Hospital Clínico Universitario de Valladolid, Valladolid, Spain

P22 COMPARISON OF THE VIRTUAL CROSSMATCH VERSUS ACTUAL CROSSMATCH IN CADAVER DONOR KIDNEY TRANSPLANTATIONBiserka Palfi 1, Natalija Martinez 1, Mirica Batarelo 1, Davorka Galenic 1, Kristina Kopic 1, Magdalena Svetec 1, Zorana Grubic 1, Renata Zunec 11University Hospital Centre Zagreb, Zagreb, Croatia

P23 HLA-SPECIFIC ANTIBODIES DETECTED BY THE BEAD ARRAY TECHNIQUE CAN ACT AS SURROGATE MARKERS FOR T- AND B-CELL FLOW CROSSMATCHESSabine Wenda 1, Daniela Koren 2, Ingrid Faé1, Gottfried F. Fischer 11Medical University Vienna, Vienna, Austria - 2General Hospital Vienna, Vienna, Austria

P24 USING FLUORESCENCE INTENSITY LEVELS BY LUMINEX TO PREDICT CROSSMATCH BY CDCCristina Abad-Molina 1, Miriam Vilches-Moreno 2, Israel Olivas-Martínez 3, Mario Cárdaba-Arranz 1, María Francisca González-Escribano 31Hospital Clínico Universitario de Valladolid, Valladolid, Spain - 2Hospital Puerta del Mar, Cádiz, Spain - 3Hospital Universitario Virgen del Rocío Sevilla, Spain



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P25 DEVELOPMENT OF SPECIFIC DONOR HLA ALLOANTIBODIES (DSAS) AFTER KIDNEY TRANSPLANTATION: A SINGLE CENTER EXPERIENCEPaola F. Zanelli 1, Roberta Merli 1, Sara Tedeschi 2, Ilaria Gandolfini 2, Umberto Maggiore 2, Adele Zanetti 11SSUO Immunogenetica dei Trapianti, Parma, Italy - 2SSUO Trapianti Rene - Pancreas, Parma, Italy

P26 SYSTEMATIC REVIEW AND REMOVAL OF UNACCEPTABLE ANTIGENS SIGNIFICANTLY IMPROVES THE CHANCE OF A KIDNEY TRANSPLANT FOR HIGHLY SENSITISED PATIENTS. A SINGLE CENTRE APPROACH IN THE UKSean B. Carey 1, Andrew Connor 1, Imran S. Saif 1, Sara Stacey 1, Linda Boorer 1, Mazen Mabrok 1, Kim Boswijk 1, Jamie Barwell 1, Anthony Poles 21Plymouth Hospitals, Plymouth, United Kingdom (Great Britain) - 2Plymouth Hospitals & Filton, Plymouth & Bristol, United Kingdom (Great Britain)

P27 IMPACT OF ANTI-HLA-DP AND -DQA ANTIBODIES IN RENAL TRANSPLANTATION: A PRELIMINARY STUDYPaola F. Zanelli 1, Valentina Sgobba 1, Roberta Merli 1, Roberta Lamanna 1, Silvia Giuliodori 1, Magda Benecchi 11SSUO Immunogenetica dei Trapianti, Parma, Italy

P28 FLOW CYTOMETRY CROSSMATCH: FCXM VS. FLOWDSA-XMGiuseppina Ozzella 1, Elvira Poggi 1, Antonio Giuseppe Bianculli 2, Damiano Colasante 2, Maria Rosaria Fazio 2, Annarita Manfreda 2, Silvia Sinopoli 2, Lucia Spano 2, Antonina Piazza 11National Council of Researches, IFT Unit of Rome S. Camillo Hospital - Regional Transplant Center of Lazio, Rome, Italy - 2Regional Transplant Center of Lazio, Rome, Italy

P29 CORRELATION OF THE DE NOVO DONOR SPECIFIC ANTI-HLA ANTIBODY (DNDSA) EMERGENCE WITH IMMUNOSUPPRESSION AND 2-YEAR LIVER TRANSPLANTATION OUTCOME: A PROSPECTIVE STUDYMarianthi Papachristou 1, Asimina Fylaktou 1, Theodoros Karampatakis 1, Evaggelos Chologitas 2, Maria Daoudaki 3, Charalampos Zarras 1, Fani Makrovasili 1, Ioannis Fouzas 41National Peripheral Histocompatibility Center, Hippokration General Hospital, Thessaloniki, Greece - 21st Internal Medicine Department, Medical School, National Kapodistrian University of Athens, Athens, Greece - 3Biochemistry Laboratory, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece - 4Solid Organ Transplantation Center, Aristotle University of Thessaloniki, Medical School, Hippokration General Hospital, Thessaloniki, Greece

P30 DISCOVERY OF A NOVEL HLA-B*08 NULL ALLELE IN A DANISH KIDNEY TRANSPLANT RECIPIENTMette Christiansen 1, Pernille B. Koefoed-Nielsen 1, Bjarne K. Møller 11Aarhus University Hospital, Aarhus N, Denmark

P31 THE ROLE OF LUMINEX-DETECTED HLA ANTIBODIES IN LONG-TERM OUTCOME OF KIDNEY TRANSPLANT: A SINGLE CENTER EXPERIENCESerena Maria Passamonti 1, Antonino Cannavò1, Francesca Poli 1, Annalisa Innocente 1, Alejandro Espadas de Arias 1, Piergiorgio Messa 1, Mariano Ferraresso 1, Massimo Cardillo 11Fondazione IRCCS Ca’ Granda- Ospedale Maggiore Policlinico, Milan, Italy

P32 INCIDENCE OF ANTI-DQ DONOR SPECIFIC ANTIBODY IN RENAL TRANSPLANT RECIPIENTS OF TERTIARY CARE HOSPITAL OF NORTH INDIAMohit Chowdhry 1, RN Makroo 1, Yogita Thakur 1, Mandhata Singh 1, Manoj Mishra 1, Vandana Sharma 11Apollo Hospital, New Delhi, India






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P33 ANTIBODY PROFILE OF STEM CELL AND ORGAN TRANSPLANTATION PATIENTS IN A SINGLE CENTERClaudia Lehmann 1, Ramona Landgraf 1, Ilias Doxiadis 11Transfusion medicine, HLA-laboratory, Leipzig, Germany

P34 OPTIMIZATION AND VALIDATION OF AN IGA HLA-SPECIFIC LUMINEX SINGLE ANTIGEN BEAD ASSAYHelena Car 1, Cynthia S.M. Kramer 1, Simone Brand-Schaaf 1, Gonca E. Karahan 1, Cees Van Kooten 2, Paul W.H.I. Parren 1, F.H.J. Claas 1, Dave L. Roelen 1, Sebastiaan Heidt 11Leiden University Medical Center, Leiden, Netherlands - 2LUMC, Leiden, Netherlands

P35 REASSESSMENT OF T-LYMPHOCYTE CROSSMATCH RESULT PREDICTION FOR ANTI-HLA-C ANTIBODIES WITH SINGLE ANTIGEN FLOW BEADS ASSAYSGwendaline Guidicelli 1, Mamy Ralazamahaleo 1, Charlene Bouthemy 1, Thoa Nong 2, Jar-How Lee 2, Jean-Luc Taupin 1, Jonathan Visentin 11Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France - 2One Lambda, Inc, Canoga Park, United States of America

P36 DETECTION AND IDENTIFICATION OF ANTI-HLA ANTIBODIES IN PATIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATIONOrjeta Bonaca 1, Eva Plesec 1, Katja Rotar 1, Blanka Vidan-Jeras 11Blood Transfusion Center of Slovenia, Ljubljana, Slovenia

P37 AXL EXPRESSION IN MIXED LYMPHOCYTE REACTIONS IN A POPULATION OF KIDNEY TRANSPLANT PATIENTSMaria Paula DP. Xavier 1, Susana Sampaio-Norton 2, José Gerardo Oliveira 31Instituto Português do Sangue e da Transplantação, Porto, Portugal - 2Hospital S. João, Serviço Nefrologia, Porto, Portugal - 3Faculdade Medicina Porto, Hospital S João, Porto, Portugal

P38 INVESTIGATION OF COSMC GENE DNA METHYLATION PROFILE AND EXPRESSION LEVEL IN IGASebahat U Akgul 1, Cigdem Kekik 1, Yasar K Caliskan 1, Egemen Cebeci 2, Erol Demir 1, Sonay Temurhan 1, Filiz Aydin 3, Fatma Oguz Savran 11Istanbul Faculty of Medicine, Istanbul, Turkey - 2Haseki Training and Research Hospital, Istanbul, Turkey - 3Istanbul Faculty of Medicine, Medical Biology Department, Istanbul, Turkey

P39 BIOMARKER FOR PROGRESSION OF IGA NEPHROPATHYSonay Temurhan 1, Sebahat U. Akgul 1, Cigdem Kekik 1, Yasar K. Caliskan 1, Yasemin Ozluk 1, Serra Ertan 1, Erol Demir 1, Halil Yazici 1, Aydin Turkmen 1, Isin Kilicarslan 1, Mehmet S Sever 1, Fatma Oguz Savran 11Istanbul Faculty of Medicine, Istanbul, Turkey



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P40 DECREASED GRAFT SURVIVAL OF RETRANSPLANTS CAN LARGELY BE EXPLAINED BY INCREASED HLA-IMMUNIZATIONElena G. Kamburova 1, B.W. Wisse 1, I. Joosten 2, W.A. Allebes 2, A. van der Meer 2, L.B. Hilbrands 2, M.C. Baas 2, Eric Spierings 1, C.E. Hack 1, F. van Reekum 1, A.D. van Zuilen 1, M.C. Verhaar 1, M.L. Bots 1, L. Plaisier 1, M.A.J. Seelen 3, J.S.F. Sanders 3, B.G. Hepkema 4, A.J. Lambeck 4, L.B. Bungener 4, C. Roozendaal 4, M.G.J. Tilanus 5, C.E. Voorter 5, L. Wieten 5, E. van Duijnhoven 5, M. Gelens 5, M. Christiaans 5, F. van Ittersum 6, A. Nurmohamed 6, N.M. Lardy 7, W.T. Swelsen 7, K.A.M.I. van der Pant 8, N.C. van der Weerd 8, I.J.M. ten Berge 8, F.J. Bemelman 8, A.J. Hoitsma 9, P.J.M. van der. Boog 10, J.W. de Fijter 10, M.G.H. Betjes 11, Sebastiaan Heidt 10, D.L. Roelen 10, F.H.J. Claas 10, H.G. Otten 11University Medical Center Utrecht, Utrecht, Netherlands - 2Radboud University Medical Center, Nijmegen, Netherlands - 3University Medical Center Groningen, Groningen, Netherlands - 4University of Groningen, University Medical Center Groningen, Groningen, Netherlands - 5Maastricht University Medical Center, Maastricht, Netherlands - 6VU University Medical Center, Amsterdam, Netherlands - 7Sanquin, Amsterdam, Netherlands - 8Academic Medical Center, Amsterdam, Amsterdam, Netherlands - 9NTS, Leiden, Netherlands - 10Leiden University Medical Center, Leiden, Netherlands - 11Erasmus Medical Center, Rotterdam, Rotterdam, Netherlands

P41 HLA-DP ANTIBODY INCOMPATIBLE TRANSPLANTATION: A SINGLE CENTRE REVIEWAdrienne Seitz 1, Katherine Mounsey 1, Ruth Foster 1, Pamela Hughes 1, Richard Baker 1, Brendan Clark 11Leeds Teaching Hospitals NHS Trusts, Leeds, United Kingdom (Great Britain)

P42 IGG SUBTYPES IDENTIFIED BY A FLOW CROSSMATCH ASSAY INCREASES SUCCESSFUL TRANSPLANTS IN SENSITIZED RECIPIENTSPrakash Rao 1, Deo Dayanand 1, David Baran 2, Mark Zucker 2, Jesus Almendral 3, Shamkant Mulgaonkar 4, Praveen Kandula 41NJ Sharing Network, New Providence, NJ, United States of America - 2Newark Beth Israel Medical Center, Newark, NJ, United States of America - 3Robert Wood Johnson University Hospital, New Brunswick, NJ, United States of America - 4Barnabas Health, Livingston, NJ, United States of America

P43 PREVALENCE OF DQA1 AND DPB1 ANTIBODIES AMONG PATIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATIONRandi Berg 1, Pernille Koefoed-Nielsen 11Aarhus University Hospital, Aarhus N, Denmark

P44 ASSESSMENT OF A PORTUGUESE PANEL REACTIVE ANTIBODY CALCULATORBruno A. Lima 1, Helena Alves 21Oficina de Bioestatística, Vilar Formoso, Portugal - 2Instituto Nacional de Saúde, Porto, Portugal

P45 LINKSĒQ™ FOR ABO, A MOLECULAR BASED SUBGROUPING SOLUTION FOR THE ABO BLOOD GROUPWilliam J. Lane 1, Helen Mah 1, Joshua M. Rodriguez 1, Thierry Viard 2, Roland Russnak 2, Vivian Yuen 2, Rania Haddad 2, Isaac Kim 2, Raymond Li 2, Zachary Antovich 21Brigham and Women's Hospital, Boston, United States of America - 2Thermo Fisher Scientific, South San Francisco, United States of America

P46 CHARACTERIZATION OF POLYMORPHISMS AT THE 3´ UNTRANSLATED REGION OF THE HLA-G GENE IN PATIENTS WITH RENAL GRAFT REJECTIONAna L. Cidral 1, Vanessa Hauer 1, Bruna C. Bertol 2, Eduardo A. Donadi 2, Maria da Graça Bicalho 11Federal University of Paraná, Curitiba, Brazil - 2University of São Paulo, Ribeirão Preto, Brazil






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P47 USEFULNESS OF INTRAGRAFT DONOR SPECIFIC ANTIBODY DETECTION IN THE CONTEXT OF ANTIBODY MEDIATED REJECTION WITHOUT CIRCULATING DONOR SPECIFIC ANTIBODIESAnne Parissiadis 1, Jerôme Olagne 2, Philippe Guntz 1, Gabriella Gautier Vargas 2, Nadine Froelich 1, Sophie Caillard 21Etablissement Français du Sang-Grand Est, Strasbourg, France - 2Hôpitaux Universitaires, Strasbourg, France

P48 DONOR HLA TYPES FROM GRAFT BIOPSIESMette Christiansen 1, Karen B. Lauridsen 2, Pernille B. Kofoed-Nielsen 11Aarhus University Hospital, Aarhus N, Denmark - 2Aalborg University Hospital, Aalborg, Denmark

P49 EPITOPE-BASED HLA MATCHING: IN SILICO STRATEGIES TO PREDICT DE NOVO DONOR-SPECIFIC ANTIBODIES IN KIDNEY TRANSPLANTATIONSandra Tafulo 1, Jorge Malheiro 2, Luísa Lobato 2, Leonídio Dias 2, António Castro-Henriques 21Portuguese Institute of Blood and Transplantation, Porto, Portugal - 2Hospital de Santo António, Centro Hospitalar do Porto, Porto, Portugal

P50 LONG TERM RESULTS OF A DESENSITIZATION PROTOCOL WITH AND WITHOUT RITUXIMAB IN HIGHLY SENSITIZED KIDNEY TRANSPLANT RECIPIENTSMoshe Israeli 1, Heftziba Green 1, Tirza Klein 1, Ruth Rachamimov 1, Sigal Eisner 1, Eviatar Nesher 1, Eytan Mor 11Rabin Medical Center, Petach-Tikva, Israel

P51 VARIABILITY OF IGG SUBCLASSES OVERTIMEDavid Pinelli 1, Muralidhar T. Gopalakrishnan 1, Anat R. Tambur 11Northwestern Univeristy, Chicago, United States of America

P52 THE ROLE OF HLA ALLELES IN SUSCEPTIBILITY TO SUSTAINED BK VIREMIA: A SINGLE-CENTER EXPERIENCESevim Gönen 1, Özant Helvacı 1, Yaşar Kandur 1, Hakan Sözen 1, Oğuz Söylemezoğlu 11Gazi University Faculty of Medicine, Ankara, Turkey

P53 A NOVEL TOOL TO DEFINE THE IMMUNOGENICITY OF HUMAN LEUKOCYTE ANTIGEN MISMATCHESCynthia S.M. Kramer 1, Johan Koster 1, Geert W. Haasnoot 1, Dave L. Roelen 1, Frans H.J. Claas 1, Sebastiaan Heidt 11Leiden University Medical Center, Leiden, Netherlands

P54 EPLET AND PIRCHE-II ANALYSIS OF ANTIBODY REACTIVITY AFTER FIRST PREGNANCYJ. Rene Duquesnoy 1, Marilyn Marrari 1, Matthias Niemann 2, Irene Hösli 3, Stefan Schaub 3, Gideon Hönger 31University of Pittsburgh Medical Center, Pittsburgh, United States of America - 2PIRCHE AG, Berlin, Germany - 3University Hospital Basel, Basel, Switzerland

P55 MONOSPECIFIC REACTIONS DETECTED BY SINGLE ANTIGENS FAIL TO DETECT NATURAL HLA ANTIGENSLaura Riesco 1, Juan Irure 1, Emilio Rodrigo 1, Marcos López-Hoyos 1, David San Segundo 11Marques de Valdecilla Universitary Hospital-IDIVAL, Santander, Spain

P56 CLINICAL SIGNIFICANCE OF LUMINEX CROSSMATCH TO DETECT PRE-TRANSPLANT DONOR SPECIFIC ANTIBODIES IN LIVING RELATED RENAL ALLOGRAFT TRANSPLANT: A SINGLE CENTER EXPERIENCEMonika Jain 1, Kumar Digvijay 1, Vinant Bhargava 1, Anurag Gupta 1, Manish Malik 1, Ashwani Gupta 1, Anil K. Bhalla 1, Devinder S. Rana 1, I. C. Verma 11Sir Ganga Ram Hospital, New Delhi, India



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P57 HLA-B*15 SNPS PREDICT THE SEROLOGICALLY DEFINED HLA-B15 SPLIT ANTIGENSBurcu Duygu 1, Benedict M. Matern 1, Christel M.H. Meertens 1, Christina E.M. Voorter 1, Marcel G.J. Tilanus 11Maastricht University Medical Center, Maastricht, Netherlands

P58 HLA MATCH AND THORACIC TRANSPLANTSPamela M. Moschini 1, Paola Magistroni 2, Elena Garino 2, Gina A. Mazzola 2, Monica Berrino 2, Silvia Alizzi 2, Tiziana Melchiorre 2, Massimo Boffini 2, Antonio Amoroso 31Azienda Ospedaliera Città della Salute e della Scienza, Turin, Italy - 2Città della Salute e della Scienza Hospital, Torino, Italy - 3University of Torino, Torino, Italy

P59 PHARMACOGENETIC EFFECTS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE POLYMORPHISMS ON MYCOPHENOLIC ACID PHARMACOKINETICS IN TURKISH RENAL TRANSPLANT PATIENTSHayriye Senturk Ciftci 1, Tzevat Tefik 2, Meltem Karadeniz Savran 3, Erol Demir 4, Ismet Nane 2, Fatma Oguz Savran 1, Aydin Turkmen 41Istanbul University, Istanbul Faculty of Medicine, Medical Biology Department, Istanbul, Turkey - 2Istanbul University, Istanbul Faculty of Medicine, Department of Urology, Istanbul, Turkey - 3Istanbul University, Istanbul Faculty of Medicine, Department of Anesthesia, Istanbul, Turkey - 4Istanbul University, Istanbul Faculty of Medicine, Department of Nephrology, Istanbul, Turkey

P60 DOES CROSSMATCH IMPACT LIVER TRANSPLANTATION OUTCOME? A SINGLE CENTER EXPERIENCEPaola Magistroni 1, Pamela M. Moschini 2, Cristiana Caorsi 1, Francesca E. Bertinetto 1, Ennia Dametto 1, Elena Navaretti 1, Lorenzo Rocchi 1, Francesco Perrone 1, Francesco Tandoi 1, Renato Romagnoli 1, Mauro Salizzoni 1, Antonio Amoroso 31Città della Salute e della Scienza Hospital, Torino, Italy - 2Azienda Ospedaliera Città della Salute e della Scienza, Turin, Italy - 3University of Torino, Torino, Italy

P61 MONITORING OF HLA-ANTIBODIES IN PATIENTS WHO UNDERWENT HEART TRANSPLANTATION IN THE REPUBLIC OF KAZAKHSTANAida Turganbekova 1, Zhandos Burkitbaev 1, Saniya Abdrakhmanova 1, Indira Ramilyeva 1, Dana Baimukasheva 1, Zhazira Saduakas 1, Perizat Zhunus 11Republic scientific and production center of transfusiology, Astana, Kazakhstan

P62 ANTIENDOTHELIAL CELL AND ANTI AT1R ANTIBODIES IN TWO CLUSTERS OF RENAL TRANSPLANT RECIPIENTS WITH ACUTE ANTIBODY MEDIATED REJECTION - A STUDY FROM A TERTIARY CENTRE IN INDIADolly Daniel 1, Santosh Varughese 1, Siddharth Mittal 1 Sam Aruldoss 1, Vinoi G. David 1, Suceena Alexander 1, Anjali Mohapatra 1, John Jude 11Christian Medical College, Vellore, India

P63 CLINICAL IMPORTANCE OF TYPE 1 ANGIOTENSIN II RECEPTOR (ATR1) Y ANTI-ENDOTELIN-1 TYPE A (ETAR) ANTIBODIES IN KIDNEY TRANSPLANTATIONJaouad El Kaaoui El Band 1, Pedro Martinez-Garcia 1, Gema Martinez-Gonzalez 1, Rafael Alfaro 1, Jose Antonio Galian 1, Francisco Boix 1, Isabel Legaz 2, Maria R. Moya-Quiles 1, Alfredo Minguela 1, Santiago Llorente 1, Manuel Muro 11Clinic University Hospital Virgen Arrixaca, Murcia, Spain - 2University of Murcia, Murcia, Spain






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P65 ASSOCIATION BETWEEN RS12917707 SINGLE NUCLEOTIDE POLYMORPHISM AT THE UMOD PROMOTER REGION AND SERUM UROMODULIN LEVELS: IMPLICATIONS IN KIDNEY TRANSPLANTATIONSilvia Deaglio 1, Ilaria Notaro 1, Alice Ianniello 2, Daniela F. Giachino 1, Daniela Biongiovanni 2, Pamela M. Moschini 3, Paola Magistroni 2 Giulio Mengozzi 2 Luca Rampoldi 4, Antonio Amoroso 11University of Turin, Torino, Italy - 2Azienda Ospedaliera Città della Salute e della Scienza, Torino, Italy - 3Città della Salute e della Scienza Hospital, Torino, Italy - 4San Raffaele Scientific Institute, Milan, Italy

P66 HLA ANTIBODY MONITORING AFTER KIDNEY TRANSPLANTATIONTjasa Kovacevic Cuculic 1, Natasa Katalinic 1, Orlic Lidija 1, Helena Kurtovic 1 Marijana Duhovic 1, Ines Simac Susanj 1, Sanja Balen 11Clinical Hospital Center, Rijeka, Croatia

P67 STARTING THE PAIRED KIDNEY DONATION PROGRAM IN GREECEAngeliki G. Vittoraki 1, Maria Darema 2, Dimitra A. Skoumi 1, Maria D. Apostolaki 1, Ioannis Bokos 2, Alexandra A. Siorenta 1, Georgios Zavvos 2, John N. Boletis 2, Aliki G. Iniotaki 11Immunology Department and National Tissue Typing Center, General Hospital of Athens, G.Gennimatas, Athens, Greece - 2Transplantation Unit, Laikon Hospital, Athens, Greece

P68 PROGNOSTIC VALUE OF A TEST ALLOWING THE DETECTION OF DONOR SPECIFIC ANTIBODY CAPABLE OF BINDING C3D AT THE TIME OF DIAGNOSIS OF HUMORAL REJECTION IN RENAL TRANSPLANT PATIENTSMarine Gatin 1, Dominique Bertrand 2, Fabienne Farce 1, Françoise Hau 11Etablissement Français du Sang Hauts de France Normandie, Bois Guillaume, France - 2CHU de Rouen, Bois Guillaume, France

P69 HIGH HLA-DPB1 EXPRESSION IN PRE-IMPLANTATION KIDNEY BIOPSIES IS ASSOCIATED WITH POOR LATE GRAFT FUNCTIONKarina L. Mine 1, Tuíla B. Mourão 1, Claudia R. Felipe 2, Gisele F. Rampim 1, José O. Medina-Pestana 2 Hélio Tedesco-Silva 2 Maria Gerbase-DeLima 11Immunogenetics Institute, São Paulo, Brazil - 2Hospital do Rim e Hipertensão, São Paulo, Brazil

P70 SERUM PRE-TREATMENT WITH FETAL BOVINE SERUM SIGNIFICANTLY INCREASES LUMINEX-BASED HLA ANTIBODY ASSAY SPECIFICITY BY REDUCING HETEROPHILE ANTIBODY INTERFERENCEAndrés Jaramillo 1, Justin L. House 1, Lora J. Nelson 1, Scott Stoll 1, Rose M. Ridgley 1, Hasan A. Khamash 11Mayo Clinic, Phoenix, Arizona, United States of America



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HAEMATOPOIETIC STEM CELL TRANSPLANTATIONP71 DISTRIBUTION OF KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTORS (KIRS) ON NK CELLS

OF HLA-MATCHED UNRELATED DONOR-RECIPIENT PAIRS RECEIVING HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT)Xiaoyan Shan 1, Dongmei Li 1, Wang Dongmei 1, Wang Zhongmei 1 Jing Yuanyuan 1, Wang Jie 11 Beijing Red Cross Blood Center, Beijing, China

P72 LOSS OF HETEROZYGOSITY RESULTS IN PRE-TRANSPLANT HLA MISTYPING IN ONE PATIENT DIAGNOSED WITH ACUTE MYELOID LEUKEMIAFeiyun Liu 1, Chuen-Ying Lin 1, Chialing Chang 1, Chi-Cheng Li 2, Ya-Chien Yang 11National Taiwan University Hospital, Taipei, Taiwan - 2National Taiwan University, Taipei, Taiwan

P73 CONTINUOUS MONITORING OF DNA EXTRACTED IN 2013 BY MEANS OF QIASYMPHONY TECHNOLOGY AND KEPT AT +4°CRayna Ivanova Derin 1, Pascale Loiseau 1, Kahina Amokrane 1, Sophie Caillat Zucman 11APHP Hôpital Saint Louis, Paris, France

P74 MICRORNA-146A AND NF-KB POLYMORPHISMS AND RISK OF ACUTE GRAFT VERSUS HOST DISEASE POST-ALLOGENEIC STEM CELL TRANSPLANTATIONGhada Mossallam 1, Raafat Abdel Fattah 1, Hossam Kamel 11National Cancer Institute, Cairo University, Cairo, Egypt

P75 ALLOGENEIC BONE MARROW TRANSPLANTATION IN THREE CASES WITH DOCK 8 DEFICIENCYTurkan Patiroglu 1, Murat Cansever 1, Alper Ozcan 1, Gulsah Uçan1, Sevgi Keles 2, Ekrem Unal 1, Chatila Talal 3, Musa Karakukcu 11Erciyes University, Kayseri, Turkey - 2Necmettin Erbakan University, Konya, Turkey - 3Harvard Medical School, Boston,United States of America

P76 Y CHROMOSOME DELETION FOUND IN CHIMERISM STR STUDYLaura Perotti 1, Lucia Longa 1, Maristella Prucca 1, Federica Piovano 1, Franco Papola 2, Carla Cervelli 2, Marco Lorenzi 11Struttura Complessa Interaziendale Immunoematologia e Medicina Trasfusionale, Cuneo, Italy - 2Centro Regionale di Immunoematologia e Tipizzazione Tissutale, Abruzzo, Italy

P77 NULL HLA-A*02:227N ALLELE IN TUMOR CELLS OF THE PATIENT WITH PERIPHERAL T-CELL LYMPHOMA, NOT OTHERWISE SPECIFIED (A CLINICAL CASE)Bella V. Biderman 1, Natalia G. Chernova 1, Igor A. Yakutik 1, Maria V. Nareiko 1, Eugene E. Zvonkov 1, Ekaterina G. Khamaganova 1, Andrey B. Sudarikov 1, Valeriy G. Savchenko 11National Research Center for Hematology, Moscow, Russian Federation

P78 PCR-SBT CHARACTERIZATION OF A NEW HLA ALLELE: B*14:58Valentina Cappuzzo 1, Francesco Ingrassia 1, Rosalba Bavetta 1, Serena Mistretta 1, Maria Blando 1, Maria Igea Vega 1, Floriana Bruno 1, Giuseppe Davì1, Raimondo Marcenò1

1Tissue Typing and Immunogenetics Laboratory, Cervello Hospital - Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy

P79 NEXT GENERATION SEQUENCING HLA TYPING: FIRST EXPERIENCE IN AN ARGENTINIAN HISTOCOMPATIBILITY LABORATORYMaria Beatriz. Rodriguez 1, Ulises Toscanini 1, Karin Padros 11PRICAI, Buenos Aires, Argentina






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P80 HIGH SIMILARITY HLA TYPING COMBINED WITH CROSS OVER IN A PATIENT WITH SICKLE CELL ANEMIAOsama Al Suraihi 1, Ahmad Bokhari 1, Nabeela Al Baz 1, Ashraf Dada 11Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia

P81 THE IMPACT OF KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTORS /HUMAN LEUKOCYTE ANTIGEN CLASS ONE COMBINATIONS ON THE ONE-YEAR PROGNOSIS OF ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN PATIENTS WITH ACUTE LEUKEMIAShirin Farjadian 1, Marzieh Mansouri 1, Jean Villard 2, Mani Ramzi 11Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran - 2Geneva University Hospital, Geneva, Swaziland

P82 DETECTING LOSS OF HETEROZYGOSITY IN HLA GENES USING NEXT-GENERATION SEQUENCING IN A PATIENT WITH APLASTIC ANEMIA Viktoria Zakharova 1, Olga Shragina 1, Elena Raykina 1, Zhanna Kuzminova 1, Michael Maschan 11Dmitry Rogachev Federal Research Centre of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation

P83 AT HEMATOPOIETIC STEM CELL TRANSPLANTATION, THE PERCENTAGE OF COINCIDENCES OF 5 LOCI OF HLA - GENES IN RELATED DONORS: IN SIBLINGS AND IN PARENTSLiudmila Alexandrovna Gracheva 1, Larisa Vladimirovna Petrova 1, Elena Vladimirovna Skorobogatova 1, Ekaterina Andreevna Pristanskova 1, Andrey Anatol'evich Bologov 11Russian Children's Clinical Hospital, Moscow, Russian Federation

P84 IDENTIFICATION OF NOVEL ALLELES WITH THE USE OF NEXT GENERATION SEQUENCINGOlga Shragina 1, Viktoria Zakharova 1, Elena Raykina 1, Michael Maschan 1, Alexei Maschan 11Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation

P85 HIGH-FIDELITY HLA GENOTYPING IN THE POLISH POPULATION WITH THE USE OF NEXT GENERATION SEQUENCINGAnna Bogacz 1, Michał Góralski 1, Alicja Bukowska 1, Mateusz Sowiński 1, Karol Jopek 1, Mariusz Gronkowski 1, Sylwia Wróblewska-Kabba 1, Michał Kolasiński 1, Hanna Skalisz 1, Krzysztof Olbromski 11Regional Blood Center in Poznan, Poznan, Poland

P86 ANTI-HLA AND DONOR SPECIFIC ANTI-HLA (DSA) IN ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION (3 YEARS EXPERIENCE)Maria Dolores De Juan 1, Larraitz Aragon 1, Nerea Olivares 2, David Monzón 1, Jose Javier Ferreiro 1, Aitziber Alkorta 11Donostia University Hospital, Donostia-San Sebastian, Spain - 2Cruces University Hospital, Bilbao, Spain

P87 DETECTION OF A NOVEL ALLELE WITH NGS HAS NEVER BEEN EASIERVera Siffnerova 1, Milena Vrana 1, Libor Kolesar 2, Efi Melista 31The Institute of Haematology and Blood Transfusion, Prague, Czech Republic - 2Omixon Biocomputing Kft., Budapest, Hungary - 3Omixon Inc., United States of America

P88 CORD BLOOD UNITS RELEASE ACTIVITY OF PADOVA CORD BLOOD BANK: SYNERGY BETWEEN CORD BLOOD BANK AND HLA LABORATORYMaria Paola Albergoni 1, Daniela Bovo 2, Aurora Strano 2, Roberta Favero 1, Genny Franceschetto 2, Giustina De Silvestro 1, Roberta Destro 21UOC Immunotrasfusionale - DIMT Padova - Azienda Ospedaliera di Padova, Padova, Italy - 2Oncoematologia Pediatrica - Padova Cord Blood Bank - Azienda Ospedaliera di Padova, Padova, Italy



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P89 COMPARISON OF UNRELATED DONOR SEARCH TIMES VIA THE NATIONAL DONOR REGISTRY AND INTERNATIONAL DONOR REGISTRIES: A SINGLE CENTER TWO YEARS EXPERIENCE FROM TURKEYEmel Gucyener 1, Fatma Savran Oguz 2, Zafer Gulbas 1, Kader Caliskan 1, Esra Isildak 1, Leman Ozel 1, Medine Hasauhadar 31Anadolu Medical Centre, Kocaeli, Turkey - 2Istanbul University, Istanbul Faculty of Medicine, Medical Biology Department, Istanbul, Turkey - 3Stem Cell Coordination Center of Turkey, Ankara, Turkey

P90 ASSESSMENT OF THE PURITY OF ISOLATED CD3+ T CELL POPULATIONS BY A NEW MOLECULAR BIOLOGY TECHNOLOGY: IMPACT ON THE QUANTIFICATION OF CHIMERISM MONITORING POST HAEMATOPOITIC STEM CELL TRANSPLANTATIONAurélie Lopasso 1, Clémence Demerle 1, Mélanie Velier 1, Sarah Dassa 1, Noura Kouba 1, Virginia Ferreira 1, Nicolino Brunet 2, Sophie Simon 1, Agnes Basire 1, Christophe Picard 31EFS PACAC, Marseille, France - 2AP-HM, Marseille, France - 3UMR7268 AMU CNRS EFS, MARSEILLE, France

P91 HLA-G 14BP DELETION EFFECT ON STEM CELL TRANSPLANTATIONSally Elfishawi 1, Raafat Abdel Fattah 11National Cancer Institute, Cairo University, Cairo, Egypt

P92 DOCUMENTATION OF RARE HLA ALLELESPedro Cano 1, Jennifer Wendel 1, Crystal Iozzino 1, Rachel Boasi 1, Yasmill Ramirez 1, Kathy Blaney 11Moffitt Cancer Center, Tampa, United States of America

P93 THE OPTIMAL DONOR PROFILE IN THE ERA OF NEXT GENERATION SEQUENCING?Vinzenz Lange 1, Gerhard Schöfl 1, Monika Füssel 1, Johannes Schetelig 2, Alexander H. Schmidt 31DKMS Life Science Lab, Dresden, Germany - 2Technische Universität Dresden, Dresden, Germany - 3DKMS, Tübingen, Germany

P94 MANAGEMENT OF DSA IN HAEMATOLOGICAL STEM CELL TRANSPLANTATIONValeria Miotti 1, Donatella Londero 1, Vincenzo De Angelis 11ASUIUD, Udine, Italy

P95 DYNAMIC TRENDS IN SEARCHING FOR MATCHED UNRELATED DONORS IN ISRAEL: A CURRENT UPDATE (2013-2017)Chen-li Levi 1, Moshe Yeshurun 1, Jerry Stein 2, Tirza Klein 1, Anat Yahel 2, Michal Sela-Navon 1, Liat Shargian 1, Oren Pasvoski 1, Moshe Israeli 11Rabin Medical Center, Petach-Tikva, Israel - 2Schneider Children’s Medical Center, Petach-Tikva, Israel

P96 THE QUANTITATIVE PCR METHOD AS METHOD OF CHOICE IN CHIMERISM MONITORING AFTER HSCTKatarina Stingl Jankovic 1, Marija Maskalan 1, Zorana Grubic 1, Marija Burek Kamenaric 1, Renata Zunec 11University Hospital Centre Zagreb, Zagreb, Croatia

P97 STRUCTURAL EPITOPE (EPLET)-BASED ANALYSIS OF HLA-ALLOIMMUNIZED PLATELET TRANSFUSIONQiang Chen 1, Mengdan Li 2, Jue Wang 31Institute of Blood Transfusion, Chinese Academy of Medical Sciences And Sichuan Cord Blood Bank, Chengdu, China - 2Sichuan Cord Blood Blank, Chengdu, China - 3Institute of blood transfusion, Chinese Academy of Medical Sciences, Chengdu, China






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P98 ROLE OF KIR RECEPTOR-HLA LIGAND MATCH/MISMATCH ON OUTCOMES IN POST TRANSPLANT CYCLOPHOSPHAMIDE BASED HAPLOIDENTICAL TRANSPLANTATIONMeenakshi Singh 1, Selma D. Silva 1, Sachin Punatar 2, Anant Gokarn 2, Avinash Bonda 2, Libin Mathew 2, Manisha Tambe 1, Sadhana Kannan 2, Sunil Rajadhyaksha 1, Navin Khattry 21Tata Memorial Hospital, Mumbai, India - 2Tata Memorial Centre, Mumbai, India

P99 FULL LENGTH NEXT GENERATION SEQUENCING (NGS) TYPING OF HLA-DPB1 ALLELES COMPRISES THE DETECTION OF ALLELE SPECIFIC FUNCTIONAL, CLINICALLY SIGNIFICANT SINGLE NUCLEOTIDE POLYMORPHISMSIngrid Faé1, Peter Kalhs 1, Sabine Wenda 1, Gottfried F. Fischer 11Medical University Vienna, Vienna, Austria

P100 DEVELOPMENT OF PERSISTENT MIXED CHIMERISM (MC) IN ALLO-HSCT TRANSPLANTED BETA-THAL PATIENTS IS ASSOCIATED WITH LOW MC EARLY AFTER TRANSPLANT AND TR1 CELLSSilvia Gregori 1, Tiziana Galluccio 2, Maria Grazia Roncarolo 3, Rosa Bacchetta 3, Marco Andreani 21San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy - 2IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 3Stanford School of Medicine, Stanford, United States of America

P101 IN SILICO PREDICTION OF NON-PERMISSIVE HLA-DPB1 MISMATCHES IN UNRELATED HCT BY FUNCTIONAL DISTANCEPietro Crivello 1, Esteban Arrieta-Bolaños 1, Bronwen E. Shaw 2, Kwang Woo Ahn 2, Hai-Lin Wang 2, Michael R. Verneris 3, Katharine Hsu 4, Joseph Pidala 5, Stephanie J. Lee 6, Katharina Fleischhauer 1, Stephen Spellman 71Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany - 2Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, United States of America - 3Pediatric BMT, University of Colorado, Aurora, United States of America - 4Memorial Sloan Kettering Cancer Center, New York, United States of America - 5Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, United States of America - 6Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, United States of America - 7Center for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be the Match, Minneapolis, United States of America

P102 AN IMPROVED SEARCH ALGORITHM BY HLA-DPB1 T CELL EPITOPE MATCHINGSendi Montanič 1, Sabina Kunilo Jamnik 1, Blanka Vidan-Jeras 11Blood Transfusion Center of Slovenia, Ljubljana, Slovenia

P103 HLA PHASED HAPLOTYPES IN SWITZERLAND, PREDICTIVE VALUE FOR MATCHED UNRELATED DONOR SEARCHES AND CLINICAL OUTCOME AFTER HSCTStéphane Buhler 1, Helen Baldomero 2, Sylvie Ferrari-Lacraz 1, José M. Nunes 3, Alicia Sanchez-Mazas 3, Stravoula Massouridi-Levrat 1, Dominik Heim 2, Joerg Halter 2, Gayathri Nair 4, Yves Chalandon 1, Urs Schanz 4, Tayfun Guengoer 5, Grazia Nicoloso 6, Jean-Marie Tiercy 1, Jakob Passweg 2, Jean Villard 11Geneva University Hospitals, Geneva, Switzerland - 2Basel University Hospital, Basel, Switzerland - 3University of Geneva, Geneva, Switzerland - 4University Hospital of Zürich, Zürich, Switzerland - 5Childrens Hospital, Zürich, Switzerland - 6Foundation Swiss Blood Stem Cells, Bern, Switzerland

P104 EASYMATCH-R: THE VALIDATION OF A WEB APPLICATION FOR DONOR QUERY IN HAEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT)Alexandre Walencik 1, Estelle Geffard 2, Sophie Limou 3, Anne Cesbron 1, Nicolas Vince2, Pierre-Antoine Gourraud 21EFS Centre-Pays de la Loire, Nantes, France - 2INSERM, Université de Nantes, Nantes, France - 3INSERM, Ecole Centrale de Nantes, Nantes, France



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P105 HAPLOIDENTICAL HAEMATOPOIETIC STEM CELL TRANSPLANTATION AND HLA- ANTIBODIES: ABOUT A CLINICAL CASE OF APPARITION OF SPECIFIC RECIPIENT ANTIBODIES DURING POST STEM CELL TRANSPLANTATION PERIODAnne Parissiadis 1, Philippe Guntz 1, Marie-Pierre Ledoux 2, Bruno Lioure 21Etablissement Français du Sang-Grand Est, Strasbourg, France - 2Hôpitaux Universitaires, Strasbourg, France

P106 INCIDENCE OF ANTI-HLA ANTIBODIES IN PAEDIATRIC PATIENTS AFFECTED BY HAEMATOLOGICAL DISEASES AND CANDIDATE TO HAEMATOPOIETIC STEM CELL TRANSPLANTP. Giustiniani 1, C. Parlavecchio 1, P. Merli 1, F. Galaverna 1, R. M. Pinto 1, S. Bordasco 1, M. Montanari 1, F. Locatelli 11Bambino Gesù Children’s Hospital, Rome, Italy

P107 REVEALING THE HIDDEN CHIMERISM BY STR GENOTYPING OF LEUKOCYTE SUBSETSGabriela Berardi 1, Cintia Llull 1, Nicolas Fernandez Escobar 2, Gregorio Jaimovich 2, Maria Beatriz Rodriguez 1, Pablo Morikone 1, Karin Padros 1, Ulises Toscanini 11PRICAI, Buenos Aires, Argentina - 2CEHT, Buenos Aires, Argentina

P108 THE IMPACT OF DONOR NATURAL KILLER CELL RECEPTOR GENES ON OUTCOME OF ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION FROM HLA-IDENTICAL SIBLING IN PATIENTS WITH ACUTE MYELOID LEUKEMIAEkaterina G. Khamaganova 1, Elena N. Parovichnikova 1, Larisa A. Kuzmina 1, Elena P. Kuzminova 1, Sergey M. Kulikov 1, Valeriy G. Savchenko 11National Research Center for Hematology, Moscow, Russian Federation

P109 OVERVIEW OF POST-TRANSPLANT MONITORING IN PATIENTS AFTER HAPLOIDENTICAL ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATIONHana Cechova 1, Kristyna Pegova 1, Lucie Pavlatova 1, Radka Zizkova 1, Pavla Hrabakova 1, Renata Prerovska 1, Martina Stankova 1, Dagmar Brezinova 11Institut of Hematology and Blood Transfusion, Prague, Czech Republic

P110 IMPACT OF ANTI-HLA ANTIBODIES ON EARLY COMPLICATIONS AND OUTCOME AFTER UNRELATED HAEMATOPOIETIC STEM CELL TRANSPLANTATIONArturas Jakubauskas 1, Rita Cekauskiene 1, Beatrice Valatkaite-Rakstiene 1, Laimonas Griskevicius 21State Research Institute Center for Innovative Medicine & Vilnius University Hospital, Vilnius, Lithuania - 2Clinics of Internal, Family Medicine and Oncology, Faculty of Medicine, Vilnius University, & Vilnius University Hospital, Vilnius, Lithuania

P111 ANALYSIS OF THE KIR GENES IMPACT ON HEMATOPOIETIC STEM CELL TRANSPLANTATION OUTCOME ACCORDING TO THREE DIFFERENT PREDICTIVE MODELS FROM LITERATUREMarija Kamenaric Burek 1, Katarina Stingl Jankovic 1, Zorana Grubic 1, Marija Maskalan 1, Ranka Serventi Seiwerth 1, Mirta Mikulic 1, Renata Zunec 11University Hospital Centre Zagreb, Zagreb, Croatia

P112 IMPACT OF NEXT-GENERATION SEQUENCING IN THE TYPING OF DONORS IN BULGARIAN BONE MARROW DONOR REGISTRYTsvetelin Lukanov 1, Lyudmila Quin 1, Antoaneta Nedyalkova 1, Bushra Al Hadra 2, Milena Ivanova 2, Elissaveta Naumova 21University Hospital Alexandrovska, Sofia, Bulgaria - 2Medical University Sofia, University Hospital Alexandrovska, Sofia, Bulgaria






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P113 AN AUDIT OF THE VOLUNTEER UNRELATED DONOR SEARCH PROCESS IN SUPPORT OF ALLOGENEIC HSCT OVER A 5 YEAR PERIODDeborah A. Sage 1, Shahram Hemmatpour1, Debbie Richardson 2, Kim Orchard 21NHS Blood and Transplant, Tooting, London, United Kingdom (Great Britain) - 2Southampton University Hospital, Southampton, United Kingdom (Great Britain)

P114 ANTI-HLA-DP ANTIBODIESPedro Cano 1, Jennifer Wendel 1, Crystal Iozzino 1, Rachel Boasi 1, Yasmill Ramirez 1, Kathy Blaney 11Moffitt Cancer Center, Tampa, United States of America

P115 LOSS OF HETEROZYGOSITY IN THE HLA REGION AND SENSITIVITY OF HLA TYPING METHODS FOR DETECTING UNDER-REPRESENTED ALLELESEszter Lazar-Molnar 1, Lori Ellinger 2, Kevin Williams 2, Ann Poles 2, Erica Andersen 1, Tracie Profaizer 3, Jamie L. Duke 4, Deborah Ferriola 4, Julio Delgado 1, Dimitri Monos 41University of Utah School of Medicine, Salt Lake City, United States of America - 2Histocompatibility and Immunogenetics Laboratory, University of Utah Health, Salt Lake City, United States of America - 3ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, United States of America - 4The Children’s Hospital of Philadelphia, Philadelphia, United States of America

IMMUNOTHERAPY, GENE THERAPY & CELLULAR THERAPYP116 MODIFICATION OF CD8+ T CELLS WITH T CELL RECEPTOR SPECIFIC FOR MINOR ANTIGEN

ACC-1YArtem M. Pilunov 1, Anna A. Kuchmiy 1, Savely A. Sheetikov 1, Nadezhda A. Bykova 1, Sergey Y. Filkin 1, Dmitry S. Romaniuk 1, Grigory A. Efimov 11National Research Center for Hematology, Moscow, Russian Federation

P117 EXPRESSION OF THE HUMAN LEUKOCYTE ANTIGEN G MOLECULE IN ERYTHROID PRECURSORS FROM AN IN VITRO CULTURE MODEL OF HUMAN CORD BLOOD CD34+ ERYTHROID PROGENITORSAurélie Lopasso 1, Monique Silvy 2, Julie Di Cristofaro 2, Pascal Bailly 2, Christophe Picard 21EFS PACAC, Marseille, France - 2UMR7268 AMU CNRS EFS, Marseille, France

BIOINFORMATICSP118 A PRECISION MEDICINE APPLICATION: PERSONALIZED CONTEXTUALIZATION OF PATIENTS

AFTER SOLID ORGAN TRANSPLANTATIONEstelle Geffard 1, Pauline Scherdel 1, Sophie Limou 1, Sophie Brouard 1, Adrien Tissot 1 Colt investigators 1, Divat Investigators 1, Antoine Magnan1, Magali Giral 1, Gilles Blancho 1, Nicolas Vince 1, Pierre-Antoine Gourraud 11INSERM, Université de Nantes, Nantes, France

P119 APPLICATION OF EASY-HLA TO 2,260 SOLID ORGAN TRANSPLANT DONOR-RECIPIENT PAIRS FROM 2 COHORTS: STATISTICALLY UPGRADED HLA TYPING FOR RESEARCH USEEstelle Geffard 1, Alexandre Walencik 2, Sophie Limou 1, Pauline Scherdel 1, Adrien Tissot 1, Divat investigators 1, Colt investigators 1, Gilles Blancho 1, Magali Giral 1, Antoine Magnan1, Anne Cesbron 2, Nicolas Vince 1, Pierre-Antoine Gourraud 11INSERM, Université de Nantes, Nantes, France - 2EFS Centre - Pays de la Loire, Nantes, France



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P120 INTRODUCING ONLINE TOOLS TO FACILITATE HLA-RELATED RESEARCHÖ. Orkun Sürel 1, Ömer Korkmaz 2, Jacob L. McCauley 3, Mehmet Tevfik Dorak 4, Mustafa Dogan 51EPROM Electronic Project & Microwave Ind. Ltd. Co., Ankara, Turkey - 2Ankara University, Ankara, Turkey - 3University of Miami, John P. Hussman Institute for Human Genomics, Miami, FL, United States of America - 4Kingston University London, Kingston, United Kingdom (Great Britain) - 5Istanbul Technical University, Istanbul, Turkey

P121 TYPELOADER FOR WINDOWS: AUTOMATED SUBMISSION OF NOVEL ALLELES IN FULL LENGTHBianca Schöne 1, Markus Fuhrmann 1, Vineeth Surendranath 1, Julia Phieler 1, Alexander H. Schmidt 2, Gerhard Schöfl 1, Vinzenz Lange 11DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany

P122 SNP-HLA REFERENCE CONSORTIUM: HLA AND SNP DATA SHARING FOR PROMOTING HLA-CENTRIC ANALYSES IN GENOMICSNicolas Vince 1, Venceslas Douillard 1, Estelle Geffard 1, Sophie Limou 1, Pierre-Antoine Gourraud 11INSERM, Université de Nantes, Nantes, France

NEW TECHNOLOGIESP123 FULL LENGTH CLASS I GENE SEQUENCING TO PREDICT THE CLASS I PROTEIN SEQUENCES

AND RULE OUT NULL ALLELES OR ALTERED PROTEIN EXPRESSIONSNezih Cereb 1, Eunsil Kim 1, Vijayaragavan Seshadri 1, Sungkyu Kim 1, Soo Young Yang1

1HistoGenetics, Ossining, New York, United States of America

P124 PERFORMANCE CHARACTERISTICS OF AN NGS-BASED HLA TYPING METHODManuela Testi 1, Manuela Catalano 1, Alessandra Moscetti 1, Lorenza Fenici 1, Lara Florean 1, Maria Rita Gallone 1, Paola Grammatico 11Medical Genetics Lab, Sapienza University, San Camillo-Forlanini Hospital, Rome, Italy

P125 VALIDATION OF NGS HLA TYPING BEFORE ITS INTRODUCTION IN THE LABORATORY ROUTINE ACTIVITYMarco Andreani 1, Manuela Testi 2, Rossella Condello 1, Giuseppe Testa 1, Mariarosa Battarra 11Laboratory of Immunogenetics and Transplant Biology - IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 2San Camillo-Forlanini Hospital, Rome, Italy

P126 HLA HAPLOTYPES IN A GREEK POPULATION BY NGS TECHNOLOGYKaterina Tarassi 1, Amanda Willis 2, Vasiliki Kitsiou 1, Kazutoyo Osoegawa 3, Diamanto Kouniaki 1, Theofilos Athanassiades 1, Marcelo Fernández-Viña3, Medhat Askar 2, Alexandra Tsirogianni 11Evangelismos Hospital, Athens, Greece - 2Baylor University Medical Center, Dallas, United States of America - 3Stanford Medical School Blood Center, Palo Alto, United States of America

P127 HLA-B*27 TYPING WITH A TRIPLEX REAL TIME PCR IN A ROUTINE LABORATORYAlice P. Pedersen 1, Menaka Andersen 1, Tore Jensen 1, Marte K. Viken 11Department of Immunology, Oslo, Norway

P128 EVALUATION OF THE NXTYPE KIT FOR HLA-TYPING WITH THE S5 IONTORRENT PLATFORMMarine Cargou 1, Charlene Bouthemy 1, Mamy Ralazamahaleo 1, Gwendaline Guidicelli 1, Jonathan Visentin 11Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France






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P129 AUTOMATION OF THE NGSGO LIBRARY PREPARATION WORKFLOW FOR HLA TYPING ON THE BIOMEK 4000 WORKSTATIONBram Luiken 1, Debby G.M. Krom 2, Gayatri C. Tetar 2, Elena Tavkin 3, Shilpa Parakh 4, Joseph Lu 4, Alisa Jackson 4, Maarten T. Penning 1, Wendy T. Swelsen 2, Neubury M. Lardy 2, Sake van Wageningen 11GenDx, Utrecht, Netherlands - 2Sanquin, Amsterdam, Netherlands - 3Beckman Coulter, Krefeld, Germany - 4Beckman Coulter, Indianapolis, United States of America

P130 STREAMLINING NGS HLA DATA ANALYSES USING NGSIGNITION AND NGSSERVERRaul Kooter 1, Job Geerligs 1, Frans-Paul Ruzius 1, Pieter Meulenberg 1, Joris Albers 1, Maarten T. Penning 1, Hanneke W.M. van Deutekom 1, Erik H. Rozemuller 11GenDx, Utrecht, Netherlands

P131 EVALUATION OF THREE LABORATORY METHODS FOR DETECTING PREFORMED HUMAN LEUKOCYTE ANTIGEN ANTIBODIESLuyanda Laura Kwofie 1, Pieter W. Meyer 11University of Pretoria, Pretoria, South Africa

P132 HIGH RESOLUTION HLA TYPING STRATEGIES: A SINGLE CENTER’S EXPERIENCEFrancesco Ingrassia 1, Valentina Cappuzzo 1, Maria Igea Vega 1, Maria Blando 1, Rosalba Bavetta 1, Serena Mistretta 1, Floriana Bruno 1, Raimondo Marcenò 11Laboratorio di Tipizzazione Tessutale ed Immunologia dei Trapianti, Medicina Trasfusionale e dei Trapianti, Palermo, Italy

P133 AN AUTOMATED WORKFLOW FOR HLA TYPING USING GenDx NGSGO ON THE TECAN FREEDOM EVO NGS WORKSTATIONReinhard Kelsch 1, Hanne Grawe 1, Bram Luiken 2, Daniel Mathow 2, Sake van Wageningen 2, Malte Heyer 3, Benjamin Vogel 3, Rafael Alvarez 3, Sirak Kifle 31Institute of Transfusion Medicine and Transplantation Immunology, Münster, Germany - 2GenDx, Utrecht, Netherlands - 3Tecan, Männedorf, Switzerland

P134 DEVELOPMENT OF FULL-GENE HLA-DPB1 NGS TYPING ON THE MISEQ AND ION S5 PLATFORMSWinnie Chong 1, Sandra G. Guerra 1, Siobhan Hamilton-Jones 1, Colin J. Brown 1, Cristina V. Navarrete 11NHS Blood and Transplant, London, United Kingdom (Great Britain)

P135 FROM THE SAMPLE TO DONOR/RECIPIENT COMPATIBILITY: A COMPREHENSIVE RANGE OF LABORATORY REAGENTS AND EQUIPMENT FOR NGS-BASED GENOTYPING OF CLASSICAL AND NON-CLASSICAL HLA GENESMehdi Alizadeh 1, Christophe Picard 2, Alexandre Walencik 3, Eric Perrot 4, Florence Bennasar 1, Sterenn Fraboulet 1, Franck Verite 1, Gilbert Semana 11Etablissement Français du Sang ETS-Bretagne, Rennes, France - 2Etablissement Français du Sang PACA-Corse, Marseille, France - 3Etablissement Français du Sang Pays de la Loire, Nantes, France - 4Etablissement Français du Sang, La Plaine Saint -Denis, France

P136 DEFINING 11 HLA LOCI IN A DIVERSE CORD BLOOD BANK USING THE ION S5Sandra G. Guerra 1, Siobhan Hamilton-Jones 1, Colin J. Brown 1, Cristina V. Navarrete 1, Winnie Chong 11NHS Blood and Transplant, London, United Kingdom (Great Britain)



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P137 A LONG-RANGE WHOLE-GENE AMPLIFICATION APPROACH FOR THE CHARACTERIZATION OF NOVEL KIR ALLELESMarie Günther 1, Kathrin Lang 1, Kuntal Worah 1, Steffen Klasberg 1, Gerhard Schöfl 1, Alexander H. Schmidt 2, André P. Mäurer 1, Vinzenz Lange 11DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany

P138 ANALYSIS OF CLASS II GENES (DRB1, DQB1, AND DPB1): IN-PHASE LONG RANGE SEQUENCING DATA PRODUCED BY USING 3RD GENERATION SEQUENCING PACBIO SMRT TECHNOLOGYNezih Cereb 1, Eunsil Kim 1, Jaejun Ryu 1, Vijayaragavan Seshadri 1, Sungkyu Kim 1, Soo Young Yang 11HistoGenetics, Ossining, New York, United States of America

P139 A NEXT GENERATION SEQUENCING BASED GENOTYPING STRATEGY FOR MICA AND MICBJens Pruschke 1, Daniel Schefzyk 1, Kathrin Lang 2, Bianca Schoene 2, Christine Gnahm 1, Vinzenz Lange 2, Alexander H. Schmidt 1, Jan Hofmann 1, Jürgen Sauter 11DKMS, Tübingen, Germany - 2DKMS Life Science Lab, Dresden, Germany

P140 HLA TYPING TO THE 3RD AND 4TH FIELD RESOLUTION: RESULTS FROM THE UK NEQAS FOR H&I PILOT EXTERNAL QUALITY ASSESSMENT SCHEMEDeborah L. Pritchard 1, M T. Rees 11Welsh Transplantation and Immunogenetics Laboratory, Pontyclun, United Kingdom (Great Britain)

P141 NGS-BASED KIR TYPING AT HIGH RESOLUTION: CHALLENGES AND SOLUTIONS FOR THE KIR FRAMEWORK GENESLoes A.L. van de Pasch 1, Sanne Vendelbosch 1, Karin van Ham 1, Hanneke W.M. van Deutekom 1, Maarten T. Penning 1, Erik H. Rozemuller 11GenDx, Utrecht, Netherlands

P142 HAPLOTYPE RESOLUTION OF MHC IN CATTLE THROUGH TARGETED ENRICHMENT AND SMRT SEQUENCINGDorothea Harrison 1, John C. Schwartz 1, Derek M. Bickhart 2, Tim P L. Smith 3, John A. Hammond 11The Pirbright Institute, Woking, United Kingdom (Great Britain) - 2Cell Wall Biology and Utilization Research, Madison, United States of America - 3Meat Animal Research Center, Clay Center, United States of America

P143 MAPPING THE STRENGTHS AND WEAKNESSES OF AN HLA NEXT GENERATION SEQUENCING WORKFLOWVicky Van Sandt 1, Aleksandar Senev 1, Johan Kerkhofs 1, Ming Li 2, Tommy Liu 2, Heylen Christine 3, Marie-Paule Emonds 11Belgian Red Cross-Flanders, Mechelen, Belgium - 2Immucor, 1916 Old Middlefield Way, Mountain View, CA 94043, United States of America - 3Immucor Transplant Diagnostics, Nijlen, Belgium

P144 BENEFITS OF AN AUTOMATED NEXT GENERATION SEQUENCING PROTOCOL FOR HLA TYPINGSue Davey 1, Dimitra Niokou 1, Zareen Deplano 1, Monica Kyriacou 1, Trevor Green 1, Vasnti Jesani-Hethcoat 1, Thusa Sathananthan 1, Colin Brown 11NHS Blood and Transplant, London, United Kingdom (Great Britain)

P145 A NOVEL NGS-BASED HIGH-RESOLUTION GENOTYPING STRATEGY FOR HLA-ELoes A.L. van de Pasch 1, Michelle van Heck 1, Remco Malestein 1, Maarten T. Penning 1, Erik H. Rozemuller 11GenDx, Utrecht, Netherlands






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P146 DEFINITIVE RESOLUTION OF HLA TYPING ERRORS AND AMBIGUITIES BY NGS TYPINGAmalia Dinou1, Maria Spyropoulou-Vlachou 2, Vasiliki Vrani 3, Efstathios Michalopoulos1, Catherine Stavropoulos-Giokas1

1Hellenic Cord Blood Bank-Biomedical Research Foundation Of the Academy of Athens, Athens, Greece - 2Alexandra General Hospital of Athens, Athens, Greece - 3General Hospital of Athens ‘’G.Gennimatas’’, Athens, Greece

P147 CONQUERING THE EFI NGS STANDARDS WITH HOLOTYPE AND TWINLibor Kolesar 1, Efi Melista 2, Nora Nagy 1, Dorrotya Berki 3, Peter Meintjes 21Omixon Biocomputing Ltd., Budapest, Hungary - 2Omixon Inc., Cambridge, United States of America - 3Omixon Biocomputing Kft., Budapest, Hungary

MHC EVOLUTION, ANTHROPOLOGY & POPULATION GENETICSP148 HLA GENES IN BARRANQUILLA (NORTH COLOMBIA): SEARCHING FOR CRYPTIC

AMERINDIAN GENESAntonio Arnaiz Villena 1, Brayan Bayona 2, Jose Palacio-Gruber 1, Ennio Hernandez 2, Ester Muñiz 1, Cristina Campos 1, Ignacio Juarez 1, Eduardo Gomez-Casado 1, José Manuel Martín-Villa 1, Carlos Silvera 21University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Immunogenetics, Universidad del Norte., Barranquilla, Colombia

P149 FREQUENCIES OF HLA GENES AND FIVE-LOCUS HAPLOTYPES OF THE OSSETIANS IN NORTH CAUCASUSElena P. Kuzminova 1, Ekaterina G. Khamaganova 1, Regina S. Chapova 11National Research Center for Hematology, Moscow, Russian Federation

P150 THE ASSOCIATION OF GENOTYPES HLA-DQ2 AND HLA-DQ8 WITH CELIAC DISEASE (CD) IN PEDIATRIC PATIENTS OF SLOVAK POPULATIONSona Penickova 1, Vladimir Bosak 21BAG Health Care GmbH, Praha 8, Czech Republic - 2Trnava University, Trnava, Slovakia

P151 NEONATAL LYMPHOPENIA SCREENING FOR DIAGNOSIS OF COMBINED IMMUNODEFICIENCY: A SINGLE CENTER STUDYTurkan Patiroglu 1, Murat Cansever 1, Aykut Poyraz 11Erciyes University, Kayseri, Turkey

P152 THE MOST FREQUENT HLA ALLELES AND HAPLOTYPES IN RUSSIAN POPULATIONS OF SAMARA AND CHELYABINSK REGIONSDmitry Y. Klyuchnikov1, Mikhail N. Vavilov 2, Larisa M. Trusova1, Tatiana A. Suslova2, Olga V. Tyumina1

1The Clinical Centre of Cell Technologies, Samara, Russian Federation - 2Chelyabinsk State University, Chelyabinsk, Russian Federation

P153 ASSOCIATION OF HLA CLASS I AND II ALLELES WITH SUSCEPTIBILITY TO SEVERE ACUTE RESPIRATORY SYNDROME INFECTION IN NORTH CHINADongmei Li 1, Yan Qiu 1, Tao Wu 2, Dongjing Liu 2, Yi Zhang 1, Wei Li11Beijing Red Cross Blood Center, Beijing, China - 2School of Public Health, Peking University, Beijing, China

P154 CHARACTERIZATION OF A NOVEL HLA-DRB1*12 ALLELE, HLA-DRB1*12:57Qiang Chen 1, Xingjie Li 2, Hai Zou 2, Mengdan Li 21Institute of Blood Transfusion, Chinese Academy of Medical Sciences And Sichuan Cord Blood Bank, Chengdu, China - 2Sichuan Cord Blood Blank, Chengdu, China



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P155 HIGH-RESOLUTION CHARACTERIZATION OF ALLELIC AND HAPLOTYPIC HLA FREQUENCIES DISTRIBUTION IN A SPANISH POPULATION USING HIGH-THROUGHPUT NEXT-GENERATION SEQUENCINGGonzalo Montero-Martin 1, Lisa E. Creary 1, Kalyan Mallempati 2, Sridevi Gangavarapu 2, Tamara Vayntrub 2, Dolores Planelles 3, Carlos Vilches 4, Jose Luis Caro 5, Maria Jose Herrero-Mata 5, Francisco Sanchez-Gordo 6, Maria Francisca González-Escribano 7, Manuel Muro 8, Maria R. Moya-Quiles 8, Rafael Gonzalez-Fernandez 9, Florentino Sanchez-Garcia 10, J. Gonzalo Ocejo-Vinyals 11, Antonio Balas 12, Jose Luis Vicario 12, Luis Marin 13, Marcelo A. Fernández-Viña 11Stanford University School of Medicine, Department of Pathology, Palo Alto, United States of America - 2Stanford Blood Center, Palo Alto, United States of America - 3Centro de Transfusiones de Valencia, Valencia, Spain - 4H. U. Puerta de Hierro, Madrid, Spain - 5Banc de Sang y Teixits, Barcelona, Spain - 6Centro de Transfusión de Málaga, Malaga, Spain - 7H. U. Virgen del Rocío, Sevilla, Spain - 8H. U. Virgen de la Arrixaca, Murcia, Spain - 9Hospital Universitario Reina Sofía, Cordoba, Spain - 10Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Spain - 11Hospital Universitario Marqués de Valdecilla, Santander, Spain - 12Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain - 13University Hospital of Salamanca (IBSAL), Salamanca, Spain

P156 HLA DP ALLELES AND HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 HAPLOTYPES BASED ON A FAMILY STUDY IN NORTH GREECEAnna Boukla 1, Asimina Fylaktou 1, Theodoros Karampatakis 1, Aikaterini Anastasiou 1, Despoina Asouhidou 1, Efthimia Evgenikaki 1, Evangelia Sidira 1, Georgia Chatzika 1, Fani Makrovasili 11National Peripheral Histocompatibility Center, Hippokration General Hospital, Thessaloniki, Greece

P157 DIFFERENT HLA-DPB1 ALLELE FREQUENCIES AMONG EARLY-ONSET AND ADULT-ONSET MULTIPLE SCLEROSIS PATIENTS AND HEALTHY CONTROLS, IN A HELLENIC COHORTMaria Anagnostouli 1, Serafeim Katsavos 1, Artemios Artemiadis 11Medical School of Athens National and Kapodistrian University, Aeginition Hospital, Athens, Greece

P158 GENETIC HLA STUDY OF KURDS IN IRAQ, IRAN AND TBILISI (CAUCASUS, GEORGIA): RELATEDNESS AND MEDICAL IMPLICATIONSAntonio Arnaiz-Villena 1, Jose Palacio-Gruber 1, Ester Muñiz 1, Cristina Campos 1, Javier Alonso-Rubio 1, Ignacio Juarez 1, Jorge Nieto 1, Shadallah Fareq Salih 2, José Manuel Martín-Villa 1, Rawand Al-Qadi 2 1University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Dohuk Specialized Laboratory Center, Dohuk, Iraq

P159 ORIGIN OF AZERIS (IRAN) ACCORDING TO HLA GENESAntonio Arnaiz Villena 1, Jose Palacio-Gruber 1, Ester Muñiz 1, Diego Rey 1, Behrouz Nikbin 2, Hosein Nickman 2, Cristina Campos 1, Rawand Al-Qadi 3, José Manuel Martín-Villa 1, Ali Amirzargar 21University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran - 3Dohuk Specialized Laboratory Center, Dohuk, Iraq

P160 HLA-G~A HAPLOTYPES IN AMERINDIANS (ECUADOR): HLA-G*01:05N WORLD DISTRIBUTIONAntonio Arnaiz Villena 1, Jose Palacio-Gruber 1, Mercedes Enriquez de Salamanca 1, Ignacio Juarez 1, Cristina Campos 1, Jorge Nieto 1, Ester Muñiz1, Rawand Al-Qadi 2, José Manuel Martín-Villa 11University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Dohuk Specialized Laboratory Center, Dohuk, Iraq

P161 NEW AND RARE ALLELES IN SOUTH TYROLS BONE MARROW REGISTRY DONORSCinzia Vecchiato 1, Evi Lochmann 1, Ivo Gentilini 11Ospedale di Bolzano, Bolzano, Italy






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P162 DETECTION OF A RARE ALLELIC VARIANT OF HLA-C*06 (C*06:76:02) IN A SPANISH PATIENTCristina Abad-Molina 1, Mario Cárdaba-Arranz 1, Antonio Balas 2, Jose Luis Vicario 2, Antonio Orduña-Domingo 11Hospital Clínico Universitario de Valladolid, Valladolid, Spain - 2Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain

P163 SUSPECTED UNEQUAL CROSSING OVER AT THE HLA-DPB1 LOCUS: A CASE REPORTCaterina Fusco 1, Carla Cervelli 2, Raffaella Azzarone 2, Roberta Penta de Vera Aragona 1, Mario Toriello 1, Giovanna Maisto 1, Laura Auriemma 1, Mimmo Ripaldi 1, Franco Papola 21AORN Santobono-Pausilipon Dipartimento Oncologia SSD BaSCO, Napoli, Italy - 2Centro Regionale di Immunoematologia e Tipizzazione Tissutale ASL1, L’Aquila, Italy

P164 STUDY OF THE ALLELIC FREQUENCIES OF A POPULATION OF BARRANQUILLA, COLOMBIACarlos H. Parga Lozano 1, Franklin Torres 2, Aracely Garcia 21Universidad del Atlántico, Barranquilla, Colombia - 2Universidad Libre, Barranquilla, Colombia

P165 A NEW UNUSUAL HLA-DQA1 ALLELE: DQA1*01Q:NEWThomas M.C. Binder 1, Wolfgang Peter 2, Tobias Roth 2, Lena Krammes 2, Sikder N.I. Rabbi 3, Reinhard Kelsch 4, Matthias Marget 1, Marco Schäfer 21Medical Center Hamburg-Eppendorf, Hamburg, Germany - 2Stefan Morsch Foundation (SMS), Birkenfeld, Germany - 3Labaid Diagnostic limited, Dhaka, Bangladesh - 4University Clinics Münster, Münster, Germany

P166 AN EXTRAORDINARY NEW HLA-B*13 ALLELEThomas M.C. Binder 1, Wolfgang Peter 2, Tobias Roth 2, Peter Trojok 2, Nicole Siebert 2, Lena Krammes 2, Reinhard Kelsch 3, Marco Schäfer 21Medical Center Hamburg-Eppendorf, Hamburg, Germany - 2Stefan Morsch Foundation (SMS), Birkenfeld, Germany - 3University Clinics Münster, Münster, Germany

P167 ASSOCIATION OF INTERLEUKIN-28B GENE POLYMORPHISMS AND HEPATITIS B CHRONIC INFECTION IN AN IRANIAN POPULATIONSadaf Asaei 1, Marzieh Jamalidoust 1, Mazyar Ziyaeyan 1, Maryam Zare 1, Mandana Namayandeh 11Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran

P168 HLA-A, -B, -C, -DRB1, -DQA1, -DQB1 AND -DPB1 ALLELE AND HAPLOTYPE FREQUENCIES DEFINED BY NEXT GENERATION SEQUENCING IN A POPULATION OF EAST CROATIA BLOOD DONORSStana Tokić 1, Veronika Žižková 2, Mario Štefanić 1, Saška Marczi 3, Katerina Sikorova 2, Marina Samardžija 3, Ljubica Glavaš-Obrovac 1, Martin Petrek 21Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia - 2Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic - 3Clinical Institute of Transfusion Medicine, Osijek University Hospital, Osijek, Croatia

P169 GENETIC DISTANCES BASED ON HLA GENE FREQUENCIES BETWEEN THE RUSSIAN DONORS OF HEMATOPOIETIC STEM CELLS FROM MOSCOW AND OTHER RUSSIAN AND WORLDWIDE POPULATIONSEkaterina G. Khamaganova 1, Elena P. Kuzminova 1, Alena R. Abdrakhimova 1, Regina S. Chapova 1, Konstantin V. Vasyukov 1, Tamara P. Chugreeva 1, Tatiana V. Gaponova 1, Valeriy G. Savchenko 11National Research Center for Hematology, Moscow, Russian Federation



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P170 HLA CLASS I ASSOCIATION STUDY WITH ALLOPURINOL INDUCED SCAR IN THE SOUTH TUNISIAN POPULATIONAida Charfi 1, Nadia Mahfoudh 1, Arwa Kamoun 1, Kamilia Ksouda 2, Hanen Affes 2, Amal Hriz 2, Khaled Zeghal 2, Hafedh Makni 11Immunology department, University Hospital Hedi Cheker, Sfax, Tunisia - 2Pharmacology department,University of Medicine, Sfax, Tunisia

P171 NEXT GENERATION SEQUENCING REVEALS HLA-DPB1 DIVERSITY IN BRITISH BONE MARROW REGISTRY VOLUNTEERS FROM DIFFERENT ETHNIC GROUPS Juliette Brown1, Sue Davey1, John Ord1, Dimitra Niokou1, Winnie Chong1 and Colin J Brown1

Histocompatibility and Immunogenetics, NHSBT, Colindale, UK1NHSBT, London, United Kingdom (Great Britain)

P172 HLA-DRB1*03:24 - A DRB1*03:01-LIKE EXON 2 SEQUENCE IN TYPICAL DRB1*13:02-HAPLOTYPEThomas M.C. Binder 1, Wolfgang Peter 2, Corinna B. Koehn 3, Lena Krammes 2, Tobias Roth 2, Christine Neuchel 4, Daniel Fuerst 4, Joannis Mytilineos 4, Kaimo Hirv 5, Reinhard Kelsch 6, Marco Schäfer 2, Thomas H. Eiermann 11Medical Center Hamburg-Eppendorf, Hamburg, Germany - 2Stefan Morsch Foundation (SMS), Birkenfeld, Germany - 3University Clinics Freiburg, Freiburg, Germany - 4German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 5Center for Human Genetics and Laboratory Diagnostics, Martinsried, Germany - 6University Clinics Münster, Münster, Germany

P173 NGS BASED HIGH-THROUGHPUT MICA AND MICB GENOTYPING OF 400,000 SAMPLESCarolin Massalski 1, Kathrin Lang 1, Jens Pruschke 2, Daniel Schefzyk 2, Jan Hofmann 2, Jürgen Sauter 2, André P. Mäurer 1, Alexander H. Schmidt 2, Vinzenz Lange 11DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany

P174 IMMUNOGENETICS OF AGEING: NEW DATA IN THE NGS ERAMilena Ivanova 1, Bushra Al Hadra 1, Tsvetelin Lukanov 2, Antoaneta Nedilakova 2, Reem Ameen 3, Michela Mazzoco 4, Nicoletta Sacchi 4, Velizar Shivarov 5, Elissaveta Naumova 11Medical University, University Hospital Alexandrovska, Sofia, Bulgaria - 2University Hospital Alexandrovska, Sofia, Bulgaria - 3Kuwait University, Jabriya, Kuwait - 4Ospedale Galliera, Genova, Italy - 5University Hospital SofiaMed, Sofia, Bulgaria

P175 A PATIENT CASE WITH SIMULTANEOUS GENE EXPRESSION OF THREE HLA-B ALLELIC VARIANTS DUE TO POINT MUTATION OBSERVED AT THE CO-EXPRESSED HLA-B*07:02 ALLELEChrysanthi Tsamadou 1, Daniel Furst 1, Christine Neuchel 1, Hubert Schrezenmeier 1, Joannis Mytilineos 11German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany

P176 EXPLORATION OF VERY LONG-RANGE LINKAGE DISEQUILIBRIUM WITHIN THE EXTENDED HLA REGIONUmut Özbek 1, Sandeep K. Singh 2, Amy E. Kennedy 3, M. Alejandro Barbieri 4, Johannes Dapprich 5, Ioanna Konidari 6, Jacob L. McCauley 6, Mehmet Tevfik Dorak 71Icahn School of Medicine at Mount Sinai; Tisch Cancer Institute, New York, NY, United States of America - 2Ohio State University, Columbus, OH, United States of America - 3National Cancer Institute, Bethesda, MD, United States of America - 4Florida International University, Miami, FL, United States of America - 5Generation Biotech, Lawrenceville, NJ, United States of America - 6University of Miami, John P. Hussman Institute for Human Genomics, Miami, FL, United States of America - 7Kingston University London, Kingston, United Kingdom (Great Britain)






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P177 QUANTIFICATION OF HLA-C SURFACE EXPRESSION IN 400 HEALTHY GERMAN BLOOD DONORS Chrysanthi Tsamadou 1, Daniel Furst 1, Markus Rojewski 2, Christine Neuchel 1, Sixten Körper 3, Hubert Schrezenmeier 1, Joannis Mytilineos 11German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 2Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 3Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service, Baden Wuerttemberg Hessen, Ulm, Germany

P178 BW4 AND BW6 EPITOPE DISTRIBUTION ON MHC CLASS I MOLECULES OF OLIVE BABOONSNanine de Groot 1, Marit K.H. van der Wiel 1, Gaby G.M. Doxiadis 1, Nel Otting 1, Natasja G. de Groot 1, Nicolas Poirier 2, Antoine Blancher 3, Ronald E. Bontrop 11Biomedical Primate Research Centre, Rijswijk, Netherlands - 2INSERM UMR 1064, Nantes, France - 3Laboratoire d’immunologie - Laboratoire d’Immunogénétique moléculaire EA 3034 - CHU de Toulouse -Faculté de médecine de Purpan, Université Paul Sabatier Toulouse 3, Toulouse, France

P179 CONFIRMED OR WELL-DETERMINED (CWD) HLA HAPLOTYPES IN EUROPE: A PRELIMINARY CATALOGUE OF THE EFI POPULATION GENETICS WORKING GROUPAlicia Sanchez-Mazas 1, José M. Nunes 1, Marco Andreani 2, Zorana Grubic 3, Derek Middleton 4, Stéphane Buhler 5, Katharina Fleischhauer 61University of Geneva, Geneva, Switzerland - 2Laboratory of Immunogenetics and Transplant Biology - IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 3University Hospital Centre Zagreb, Zagreb, Croatia - 4Royal Liverpool and Broadgreen University Hospital, Liverpool, United Kingdom (Great Britain) - 5Geneva University Hospitals, Geneva, Switzerland - 6Essen University Hospital, Essen, Germany

P180 BUILDING A HIGH RESOLUTION HAPLOTYPE DATABASE FOR 11 HUMAN LEUKOCYTE ANTIGEN LOCI FROM FAMILY TRIOSEvan Kountouris 1, Douglas Levinson 2, Marcelo A. Fernández-Viña 3, Hanna Ollila 1 Emmanuel Mignot 4, Ming Tsuang 5, Stephen Glatt 6, Ming Li 1, Michael Mindrinos 11Immucor, Mountain View, United States of America - 2Stanford University School of Medicine, Palo Alto, United States of America - 3Stanford University Medical Center, Palo Alto, United States of America - 4Stanford Center for Sleep Sciences and Medicine, Palo Alto, United States of America - 5University of California San Diego, San Diego, United States of America - 6SUNY Upstate Medical University, Syracuse, United States of America

P181 MARKOV CHAIN MODELLING BRINGS NEW CLUES ON HLA EVOLUTIONARY HISTORYThomas Goeury 1, Jose M. Nunes 1, Alicia Sanchez-Mazas 11University of Geneva, Geneva, Switzerland

P182 HLA-C ALLELE SPECIFIC EXPRESSION IN CHINESE HAN POPULATIONJiang Li 1, Wang Jue 2, Qiang Chen 11Institute of Blood Transfusion, Chinese Academy of Medical Sciences And Sichuan Cord Blood Bank, Chengdu, China - 2Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China

P183 ANALYSIS OF NEW, VERY RARE AND RARE HLA ALLELES AMONG VOLUNTEER HEMATOPOIETIC STEM CELL DONORS IN CROATIAN BONE MARROW DONOR REGISTRYMarija Kamenaric Burek 1, Zorana Grubic 1, Marija Maskalan 1, Katarina Stingl Jankovic 1, Danijela Clekovic 1, Renata Zunec 11University Hospital Centre Zagreb, Zagreb, Croatia



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P184 APPROXIMATING ADMIXTURE IN LATIN AMERICAN POPULATIONS USING ANALYSIS OF HIGH-RESOLUTION HLA EXTENDED HAPLOTYPES: DIFFERENTIAL ADMIXTURE PROPORTIONS IN NEIGHBORING COUNTRIESEsteban Arrieta-Bolaños 1, Víctor Acuña-Alonzo 2, Rodrigo Barquera 3, Juan José Madrigal-Sánchez 4, Jeremy E. Stein 5, Priscilla Órlich-Pérez 6, María José Moreira-Espinoza 7, Edel Paredes-Carias 7, Yondra Vanegas-Padilla 7, Lizbeth Salazar-Sánchez 4, J. Alejandro Madrigal 8, Steven G.E. Marsh 8, Bronwen E. Shaw 91Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany - 2Laboratorio de Genética Molecular, Escuela Nacional de Antropología e Historia, México City, Mexico - 3Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany - 4Escuela de Medicina, Universidad de Costa Rica, San José, Costa Rica - 5Anthony Nolan Research Institute, Royal Free Hospital, London, United Kingdom (Great Britain) - 6División de Banco de Células Madre, Laboratorio Clínico, Hospital San Juan de Dios, San José, Costa Rica - 7Departamento de Ciencias Morfológicas, Universidad Nacional Autónoma de Nicaragua, León, Nicaragua - 8Anthony Nolan Research Institute & UCL Cancer Institute, London, United Kingdom (Great Britain) - 9Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, United States of America

P185 THE EFFECT OF HLA AND SNPS ON ESRD DEVELOPMENT IN IGAN PATIENTSCigdem Kekik 1, Sonay Temurhan 1, Sebahat U Akgul 1, Yasar K Caliskan 1, Yasemin Ozluk 1, Serra Ertan 1, Erol Demir 1, Figen Abatay 1, Halil Yazici 1, Aydin Turkmen 1, Kilicarslan Isik 1, Mehmet S Sever 1, Fatma Oguz Savran 11Istanbul Faculty of Medicine, Istanbul, Turkey

P186 MAJOR HISTOCOMPATIBILITY COMPLEX ALLELE PERSISTENCE IN EURASIA AND AMERICA IN THE GENUS CARDUELIS (GOLDFINCHES) DURING MILLION YEARSAntonio Arnaiz-Villena 1, Valentín Ruiz-del-Valle 1, Ester Muñiz1, Jose Palacio-Gruber1, Cristina Campos 1, Eduardo Gomez-Casado 1, José Manuel Martín-Villa 1, Ignacio Serrano-Vela 11University Complutense, The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain

P187 HLA GENES IN ATLANTIC CELTIC POPULATIONS: ARE CELTS IBERIANS?Antonio Arnaiz-Villena 1, Ana Carballo 1, Ignacio Juarez 1, Ester Muñiz 1, Cristina Campos 1, Rawand Al-Qadi 2, Jorge Nieto 1, José Manuel Martín-Villa 1, Jose Palacio-Gruber 11University Complutense, The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Dohuk Specialized Laboratory Center, Dohuk, Iraq

P188 MICA AND NKG2D DISEASE-COMMON VARIANTS IN A FRENCH COHORT OF PATIENTS WITH SPONDYLOARTHRITISMarie Fechtenbaum 1, Judith Desoutter 1, Vincent Goeb 1, Nicolas Guillaume 11Amiens University Medical Center, Amiens, France

P189 HIGH RESOLUTION HLA-A, -B, -C, -DRB1 AND -DQB1 ALLELE AND HAPLOTYPE FREQUENCIES FOR ARAB DONORS IN THE HADASSAH BONE MARROW DONOR REGISTRYAmal Bishara 1, Michael Halagan 2, Chaim Brautbar 1, Shoshana Israel 1, Martin Maiers 2, Abeer Madbouly 21Hadassah-Hebrew University Medical Center, Jerusalem, Israel - 2National Marrow Donor Program, Minneapolis, MN, United States of America

P190 THE RELEVANCE OF NGS TYPING IN UNRAVELING THE DIVERSITY OF 11 HLA LOCI TYPED IN THE MEXICAN MESTIZOS FROM OAXACA, MEXICOAndrea Munguia 1, Lisa E. Creary 2, Marcelo A. Fernández-Viña 2, Betsy González 3, Hilario Flores-A 3, Clara Gorodezky 31Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health, México City, Mexico - 2Stanford University School of Medicine, Palo Alto, CA, United States of America - 3Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health & Fundación comparte Vida A.C., México City, Mexico






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P191 THE IMMUNOGENETIC FINGERPRINT OF THE INHABITANTS OF THE ITALIAN CALABRIA REGION: DISTRIBUTION OF HLA-A, -B, -C ALLELES IN FOUR PROVINCES COMPARED TO ELEVEN MODERN DESCENDANTS OF THEIR INVADERSCristina Capittini 1, Marina Francone 2, Valeria Calantoni 2, Rita E. Saladino 2, Annalisa De Silvestri 1, Carmine Tinelli 3, Giuseppa Romeo 21IRCCS Policlinico San Matteo Foundation, Pavia, Italy - 2A.O. Bianchi Melacrino Morelli, Reggio Calabria, Italy - 3IRCCS Policlinico San Matteo Foundation, Pavia, Italy

P192 DISTRIBUTION OF HLA-DRB1 ALLELES ASSOCIATED WITH RHEUMATOID ARTHRITIS IN SPLIT-DALMATIA COUNTY IN SOUTHERN CROATIAIvanka Marinovic 1, Sonja Jaman 1, Esma Cecuk-Jelicic 1, Duska Martinovic-Kaliterna1, Jela Mratinovic-Mikulandra 11University Hospital Centre Split, Split, Croatia

P193 IMPACT OF HLA-A~B~DRB1 HAPLOTYPE POLYMORPHISMS ON DONOR SELECTION IN HEMATOPOIETIC STEM CELL TRANSPLANTATION PROGRAM IN CROATIAMarija Maskalan 1, Zorana Grubic 1, Marija Burek Kamenaric 1, Danijela Svilicic 1, Katarina Stingl Jankovic 1, Renata Zunec 11University Hospital Centre Zagreb, Zagreb, Croatia

P194 HLA PROFILES IN THE POPULATION OF MOLDOVAVera Sali1, Corina Cianga2,3, Natalia Isac1, Elena Cuiban1, Daniela Constantinescu2,3, Camelia Mihaila3, Petru Cianga2,31 HLA Laboratory, Republican Clinical Hospital Timofei Mosneaga, Chisinau, Republic of Moldova - 2 Department of Immunology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania - 3 Laboratory of Immunology and Genetics, “Sf. Spiridon” Hospital, Iasi, Romania

NK & NON-MHCP195 A CONFIRMATIVE STUDY TO VERIFY THE ACCURACY OF OUR NGS BASED WORKFLOW AND

SOFTWARE FOR HIGH-RESOLUTION KIR GENOTYPINGBianca Heyn 1, Jill A. Hollenbach 2, Paul J. Norman 3, Annett Heidl 1, Alexander H. Schmidt 4, Jürgen Sauter 4, Vinzenz Lange 11DKMS Life Science Lab, Dresden, Germany - 2University of California, San Francisco School of Medicine, San Francisco, United States of America - 3University of Colorado, Denver, CO, United States of America - 4DKMS, Tübingen, Germany

P196 ROLE OF TELOMERIC INHIBITOR KIR GENES IN ALCOHOL CIRRHOSISIsabel Legaz 1, José M. Bolarin 2, José A. Campillo 2, Maria R. Moya-Quiles 2, Lourdes Gimeno 2, Ana M. Garcia-Alonso 2, Maria Rocio Alvarez-Lopez 2, Alfredo Minguela 2, Manuel Muro 21University of Murcia, Murcia, Spain - 2Clinic University Hospital Virgen Arrixaca, Murcia, Spain

P197 IDENTIFICATION OF MHC CLASS IB LIGANDS FOR STIMULATORY AND INHIBITORY LY49 RECEPTORS AND INDUCTION OF POTENT NK ALLORESPONSES IN RATSKe-Zheng Dai 1, John Torgils Vaage 1, Christian Naper 11Oslo University Hospital - Rikshospitalet, Oslo, Norway

P198 KIR 3DL1-EDU, HLA GENOTYPES AND KIR HAPLOTYPE INFLUENCE CLINICAL OUTCOME OF HIGH-RISK YOUNG MULTIPLE MYELOMA PATIENTS TREATED UP-FRONT WITH NOVEL AGENTSSebastiana Toscano 1, Fabrizio Puglisi 2, Alessandra Romano 2, Etta Conticello 2, Marina Parisi 2, Valeria Calafiore 2, Enrica Martino 2, Salvatore Leotta 2, Francesco Di Raimondo 2, Grazia Sortino 1, Maria Pia Azzaro 11 Tissue Typing Laboratory - Hematology and Bone Marrow Transplantation Units - Policlinico Vittorio Emanuele, Catania, Italy - 2UOC Hematology and Bone Marrow Transplantation Units - AOU Policlinico Vittorio Emanuele, Catania, Italy



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P199 ASSOCIATION OF KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR KIR2DS1 WITH PSORIASIS IS INDEPENDENT OF HLA-C*06:02Sandro Orrù 1, Maria Antonietta Montesu 2, Nicola Orrù 3, Erika Giuressi 3, Rosanna Satta 2, Giuliana Onnis 2, Paola Ragatzu 1, Daniela Diana 1, Selene Cipri 1, Roberto Littera 3, Alberto Cauli 4, Carlo Carcassi 11Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 2Dermatology Unit, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy - 3Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 4Chair of Rheumatology and Rheumatology Unit, AOU University Clinic of Cagliari, Cagliari, Italy

P200 KILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR GENES AND HLA IN RELAPSING-REMITTING MULTIPLE SCLEROSISEleonora Cocco 1, Elena Congeddu 2, Selene Cipri 2, Paola Ragatzu 2, Sara Lai 3, Rita Porcella 3, Francesco Alba 3, Valentina Loi 3, Maria Serra 3, Roberta Maddi 3, Cristina Melis 4, Lucia Schirru 4, Daniela Corongiu 4, Stefania Tranquilli 1, Jessica Frau 1, Roberto Cusano 5, Maurizio Melis 2, Roberta Murru 3, Carlo Carcassi 21Multiple Sclerosis Center, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 2Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 3Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 4Multiple Sclerosis Center, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 5Center for Advanced Studies, Research and Development (CRS4), Pula, Italy

P201 KIR3DL1/S1 NATURAL KILLER CELL IMMUNOGLOBULIN LIKE RECEPTORS (KIR) DISTRIBUTION AND THEIR HLA CLASS I LIGANDS IN MEXICAN MESTIZOS FROM MEXICO CITYBetsy González 1, Guadalupe Sánchez 2, Andrea Munguia 3, Miriam Valencia 3, Hilario Flores-A 1, Clara Gorodezky 11Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health & Fundación comparte Vida A.C., México City, Mexico - 2Fundación Comparte Vida, A.C., Mexico City, Mexico - 3Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health, México City, Mexico

P202 DIVERSITY OF C1, C2, BW4, A3/11 AND BW6 AMINO ACID MOTIFS IN WHOLE HLA:KIR INTERFACESlawomir Gwozdowicz 1, Klaudia Nestorowicz 1, Urszula Szlendak 1, Jacek Nowak 11Institute of Hematology and Transfusion Medicine, Warsaw, Poland

P203 EVALUATION OF NK CELL CYTOTOXICITY BIOMARKERS OF TUMOR PROGRESSION IN BREAST CANCERAngelica Canossi 1, Anna Aureli 1, Tiziana Del Beato 1, Giorgio Novelli 2, Oreste Buonomo 2, Giuseppe Sconocchia 31CNR Translational Pharmacology, L’Aquila, Italy - 2Department of Systems Medicine, Rome, Italy - 3CNR Translational Pharmacology, Rome, Italy

P204 THE HYBRID GENE KIR2DS2*005 IS CARRIED BY TWO HAPLOTYPES DIFFERING IN THE TELOMERIC REGIONMaria Bono 1, Alice Bertaina 2, Edoardo Lanino 1, Marco Zecca 3, Daniela Pende 4, Alessandro Moretta 5, Franco Locatelli 2, Lorenzo Moretta 6, Cristina Bottino 5, Michela Falco 11Institute Giannina Gaslini, Genoa, Italy - 2IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy - 3IRCCS Policlinico San Matteo Foundation, Pavia, Italy - 4IRCCS Ospedale Policlinico San Martino, Genoa, Italy - 5Università degli Studi di Genova, Genoa, Italy - 6Ospedale Pedriatico Bambino Gesù, Rome, Italy

P205 IDENTIFICATION AND EXPRESSION OF NOVEL IMMUNOGLOBULIN-LIKE GENES ENCODED BY THE LEUKOCYTE RECEPTOR COMPLEX (LRC) IN PIGSJohn C. Schwartz 1, John A. Hammond 11The Pirbright Institute, Woking, United Kingdom (Great Britain)






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P206 INFLUENCE OF KIR2DL2/L3 GENES IN THE DEVELOPMENT OF ALCOHOLIC CIRRHOSISIsabel Legaz 1, José M. Bolarín2, José A. Campillo 2, Maria R. Moya-Quiles 2, Lourdes Gimeno 2, Ana M. Garcia-Alonso 2, Maria Rocio Alvarez-Lopez 2, Alfredo Minguela 2, Manuel Muro 21University of Murcia, Murcia, Spain - 2Clinic University Hospital Virgen Arrixaca, Murcia, Spain

REPRODUCTION, AUTOIMMUNITY, INFECTION & CANCERP207 ANALYSIS OF THE FREQUENCIES OF HLA-C LOCUS IN PATIENTS WITH RHEUMATIC

DISEASESCristina Abad-Molina 1, Miriam Vilches-Moreno 2, Mario Cárdaba-Arranz 1, Mercedes Nocito-Colón1, Antonio Orduña-Domingo 1, Jesús Ontañón-Rodríguez 31Hospital Clínico Universitario de Valladolid, Valladolid, Spain - 2Hospital Puerta del Mar, Cádiz, Spain - 3Hospital General Albacete, Albacete, Spain

P208 HLA ALLELE INVESTIGATION IN PSORIASIS AS A POSSIBLE TRANSLATIONAL APPROACHSara Autolitano 1, Valeria Calantoni 1, Giuseppa Romeo 1, Marina Francone 1, Natale Imbesi 1, Francesco Turiano 1, Silvia Cafarelli 1, Anna Maria Verduci 1, Rita E. Saladino1

1A.O. Bianchi Melacrino Morelli, Reggio Calabria, Italy

P209 TNF-ALPHA GENE POLYMORPHISMS IN ROMANIAN PATIENTS WITH CROHNS DISEASEM. Olivia Popa 1, Cristian Tieranu 2, Mihai Bojinca 1, Monica I. Dutescu 3, Ioana Tieranu 1, Constantin Bara 1, Mircea Diculescu 11University of Medicine and Pharmacy ‘Carol Davila’, Bucharest, Romania - 2Elias University Emergency Hospital, Bucharest, Romania - 3’Prof. Dr. C. T. Nicolau’ National Institute of Blood Transfusion, Bucharest, Romania

P210 HLA CLASS I MOLECULES AS KIR LIGANDS IN PSORIASIS SUSCEPTIBILITYMarco Guarene 1, Vittorio Bolcato 1, Adriana Piccolo 1, Ilaria Sbarsi 1, Cinzia Pizzochero1, Rosalia Cacciatore 1, Paola Bergamaschi 1, Annamaria Pasi 1, Valeria Brazzelli 11IRCCS Policlinico San Matteo Foundation, Pavia, Italy

P211 COMPARISON OF HLA-DQA1, DQB1, AND DRB1 ALLELES BETWEEN HEALTHY INDIVIDUALS AND CELIAC PATIENTSTulay Kilicaslan Ayna 1, Asli Ozkizilcik Kocyigit 1, Asli Eldem 1, Derya Gulec 1, Murat Kilicoglu 1, Mustafa Soyoz 11Tepecik Training and Research Hospital, Izmir, Turkey

P212 HLA AND NEFRIT TUBULES- INTERSTITIAL AND UVEITERita D’Auria 1, Antonella Manzo 1, Marika Petrillo 1, Antonio Vitale 2, Maria Majorana2, Michele Cirella 1, Agata De Feo 1, Paolo di Maio 1, Antonio De Sapio 1, Anna Elisa Laserra 11A.O.R.N. San G. Moscati SIMT, Avellino, Italy - 2A.O.R.N. San G. Moscati Pediatria, Avellino, Italy

P213 INVESTIGATION OF HLA-B*51 SUB-ALLELES IN TURKISH PATIENTS WITH BEHCETS DISEASESinem Topcu 1, Tulay Kilicaslan Ayna 1, Handan Kelekci 2, Murat Kilicoglu 1, Burcu Cerci Gurbuz 1, Asli Ozkizilcik Kocyigit 1, Mustafa Soyoz 11Tepecik Training and Research Hospital, Izmir, Turkey - 2İzmir Katip Celebi University Atatürk Education and Research Hospital, Izmir, Turkey



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P214 ASSOCIATIONS OF CYTOKINE POLYMORPHISMS AND CYTOGENETIC PROFILES IN MULTIPLE MYELOMA PATIENTS FROM THE NORTH-WEST REGION OF RUSSIAAnastasia Pavlova 1, Irina Pavlova 2, Ludmila Bubnova 2, Stanislav Bessmeltsev 2, Elizaveta Kleina 2, Andrey Gariffulin 2, Irina Martynkevich 2, Sergey Voloshin 2, Aleksandr Chechetkin 21Russian Institute of Haematology and Transfusion; Saint-Petersburgs Multidisciplinary Medical Center named after I.P. Pirogov, St. Petersburg, Russian Federation - 2Russian Institute of Haematology and Transfusiology, St. Petersburg, Russian Federation

P215 GENETIC DIVERSITY OF INTERLEUKIN-6 AND ITS RECEPTOR AND PLASMA INTERLEUKIN-6 LEVELS IN BIPOLAR DISORDER: AN INDO-FRENCH STUDYAparna Sundaresh 1, José Oliveira 1, Raj Kumar Chinnadurai 2, Ravi Philip Rajkumar2, Lylia Hani 3, Rajagopal Krishnamoorthy 3, Marion Leboyer 1, Vir Singh Negi 2, Ryad Tamouza 11Inserm U955, Créteil, France - 2Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India - 3Hôpital Saint-Louis, Paris, France

P216 MOLECULAR ANALYSIS OF HUMAN PARVOVIRUS B19 NON-STRUCTURAL PROTEIN GENE EXPRESSION IN TRANSFECTED HEK-293T EPITHELIAL CELL LINE AND ITS CORRELATION WITH ACTIVATION OF INFLAMMATORY RESPONSESedigheh Jalali 1, Abbas Behzad-Behbahani 1, Gholam-Reza Rafiei-Dehbidi 1, Shirin Farjadian 1, Ali Farhadi 11Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran

P217 SCHIZOPHRENIA AND HLA: WORK IN PROGRESS ABOUT HLA TYPING USEFULNESS AND DIAGNOSTIC THERAPEUTIC OUTLOOKSRita E. Saladino 1, Giuseppa Romeo 1, Marina Francone 1, Valeria Calantoni 1, Sara Autolitano 1, Alessia Stranges 1, Silvia Cafarelli 1, Anna Maria Verduci 1, Manuel Mercurio 1, Natale Imbesi 1, Michele Zoccali 2, Giuseppe Libri 2, Carmela Palumbo 2, Filomena Salvadori 21A.O. Bianchi Melacrino Morelli, Reggio Calabria, Italy - 2Azienda Sanitaria Provinciale n. 5, Reggio Calabria, Italy

P218 GENETIC VARIABILITY IN TLR10 GENE MAY MODULATE THE SUSCEPTIBILITY TO RHEUMATOID ARTHRITIS AND RESPONSE TO TREATMENT WITH ITNF-ALPHABarbara Wysoczanska 1, Marta Puchala 1, Jerzy Swierkot 2, Katarzyna Kolossa 3, Slawomir Jeka 3, Katarzyna Bogunia-Kubik 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2Wroclaw Medical University, Wrocław, Poland - 3Hospital University Number 2 Jana Biziela, Bydgoszcz, Poland

P219 HLA-I-NEGATIVE/PD-L1-POSITIVE NON-SMALL CELL LUNG CANCER HAS MORE AGGRESSIVE PHENOTYPE AND A LOW GRADE OF IMMUNE INFILTRATIONFrancisco Perea 1, Abel Sánchez-Palencia 1, Mercedes Gómez-Morales 2, Míguela Méndez García 1, Ángel Concha 3, Amanda Rocío González-Ramírez 4, Teresa Cabrera 5, Federico Garrido 1, Francisco Ruiz-Cabello 1, Natalia Aptsiauri 51Hospital Universitario Virgen de las Nieves, Granada, Spain - 2 Universidad de Granada,, Granada, Spain - 3Complejo Hospitalario Universitario, La Coruña, Spain - 4Fundación de Investigación Biosanitaria Alejandro Otero, Granada, Spain - 5Universidad de Granada, Granada, Spain

P220 ALLELE C07 AND PSORIASISRita D’Auria 1, Antonella Manzo 1, Marika Petrillo 1, Raffaele Iandoli 2, Michele Cirella1, Antonio Bottone 1, Paolo di Maio 1, Mattia Verosimile 1, Vito Colacurcio 1, Anna Elisa Laserra 11A.O.R.N. San G. Moscati SIMT, Avellino, Italy - 2A.O.R.N. San G. Moscati Dermatologia, Avellino, Italy






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P221 THE ASSOCIATION OF IL-17 GENE POLYMORPHISMS AND THE RISK OF BLADDER CANCER IN A POLISH POPULATION: PRELIMINARY DATAAnna Tomkiewicz 1, Wojciech Krajewski 2, Anna Kolodziej 2, Romuald Zdrojowy 2, Janusz Dembowski 2, Anna Partyka 1, Irena Frydecka 1, Lidia Karabon 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2Wroclaw Medical University, Wroclaw, Poland

P222 ROLE OF HLA-G EXON 8 POLYMORPHISM IN CONFERRING GENETIC SUSCEPTIBILITY TO TYPE 1 DIABETES AMONG NORTH INDIANSUma Kanga 1, Manish Mourya 1, Nikhil Tandon 2, Poonam Coshic 31Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India - 2Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India - 3Transfusion Medicine, All India Institute of Medical Sciences, New Delhi, India

P223 IL-23R GENE POLYMORPHISMS CONFERS SUSCEPTIBILITY TO BLADDER CANCER IN A POLISH POPULATION: A PRELIMINARY DATAAnna Tomkiewicz 1, Anna Partyka 1, Wojciech Krajewski 2, Anna Kolodziej 2, Janusz Dembowski 2, Romuald Zdrojowy 2, Irena Frydecka 1, Lidia Karabon 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2Wroclaw Medical University, Wroclaw, Poland

P224 BTLA GENE POLYMORPHISMS IN MULTIPLE MYELOMA IN A POLISH POPULATIONAnna Partyka 1, Dariusz Woszczyk 2, Marek Kielbinski 3, Irena Frydecka 1, Lidia Karabon 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2State Hospital, Opole, Poland - 3Medical University, Wroclaw, Poland

P225 LOH AND DOWNREGULATION OF THE APM COMPONENTS ARE THE KEY MECHANISMS OF THE LOSS OF HLA CLASS I EXPRESSION IN LUNG CANCERFrancisco Perea 1, Martin Kerick 2, Monica Bernal 1, Javier Martin 2, Abel Sánchez-Palencia 1, Teresa Cabrera 3, Federico Garrido 1, Natalia Aptsiauri 3, Francisco Ruiz-Cabello 11Hospital Universitario Virgen de las Nieves, Granada, Spain - 2Instituto de Parasitology Biomedicina López Neyra, CSIC, Granada, Spain - 3Universidad de Granada, Granada, Spain

P226 C4 COPY NUMBER VARIATIONS IN PSYCHIATRIC AND AUTOIMMUNE DISORDERSChristina Mary Mariaselvam 1, Aparna Sundaresh 1, Céline Manier 1, Ravi Philip Rajkumar 2, Rajagopal Krishnamoorthy 3, Marion Leboyer 1, Vir Singh Negi 2, Ryad Tamouza 11Henri Mondor Hospital, Créteil, France - 2Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India - 3Saint Louis Hospital, Paris, France

P227 PREVALENCE OF HLA B*57 AMONG HIV-1 POSITIVE PATIENTS IN THE AEGEAN REGION OF TURKEYMurat Kilicoglu 1, Derya Gulec 1, Tulay Kilicaslan Ayna 1, Mustafa Soyoz 1, Sukran Kose 11Tepecik Training and Research Hospital, Izmir, Turkey



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P228 ROLE OF HLA-G IN AUTOIMMUNE HEPATITISRoberto Littera 1, Sara Lai 1, Elena Congeddu 2, Paola Ragatzu 2, Selene Cipri 2, Maria Donatella Valentini 1, Luisella Cappai 1, Rita Porcella 1, Francesco Alba 1, Maria Serra 1, Valentina Loi 1, Roberta Maddi 1, Maurizio Melis 2, Roberto Cusano 3, Marcello Trucas, Sandro Orrù 2, Luchino Chessa 5, Simona Onali 5, Francesco Figorilli 5, Carlo Carcassi 21Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 2Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 3Center for Advanced Studies, Research and Development (CRS4), Pula, Italy - 4School of Clinical Pathology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 5Center for the Study of Liver Diseases, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

P229 THE ASSOCIATION OF ERAP1 AND ERAP2 SINGLE NUCLEOTIDE POLYMORPHISMS WITH RECURRENT SPONTANEOUS ABORTIONKarolina Wilczyńska 1, Andrzej Wiśniewski 1, Aleksandra Bylińska 1, Ewa Barcz 2, Andrzej Malinowski 3, Jacek Wilczyński 4, Piotr Kuśnierczyk 1, Izabela Nowak 11Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Medical University of Warsaw, Warszawa, Poland - 3Polish Mothers Memorial HospitalResearch Institute, Łódź, Poland - 4Medical University of Lodz, Łódź, Poland

P230 DISTRIBUTION OF HLA CLASS I AND CLASS II ALLELES IN IGA DEFICIENCY PATIENTS FROM CANTABRIA (NORTHERN SPAIN)Laura Riesco Dávila 1, Fernando Ausín Ortega 1, Marcos López Hoyos 1, J. Gonzalo Ocejo-Vinyals 11Hospital Universitario Marqués de Valdecilla, Santander, Spain

P231 CAN WE WIN OR CAN'T WIN CANCER? RESEARCH SHOWS US A REAL HOPEAnna Maria Berghella 1, Anna Aureli 1, Angelica Canossi 1, Ida Anna Contasta 1, Giuseppe Marulli 2, Roberto Lattanzio 3, Giancarlo Di Gregorio 4, Tiziana Del Beato 1, Enzo Secinaro 5, Patrizia Pellegrini 11Institute of Translational Pharmacology, L'Aquila, Italy - 2L'Aquila Hospital, l'Aquila, Italy - 3Popoli-Pescara Hospital, Popoli, Italy - 4Popoli-Pescara Hospital, Italy - 5Chieti-Hospital, Italy

P232 HLA-DQ GENOTYPE AND RISK FOR COELIAC DISEASE IN NORTHERN GREEK PATIENTSPanagiota Lazidou 1, Maria Fotoulaki 1, Alexandra Fleva 1, Fotini Sotiriadou 1, Maria Markopoulou 1, Christina Aggelopoulou 1, Athanasios Dardas 1, Anastasia Giannakou 11Papageorgiou General Hospital, Thessaloniki, Greece

P233 BEHCET LIES IN THE EYE OF THE B-HOLDERSally Elfishawi 1, Ghada Mossallam 1, Mohanad Elfishawi 2, Helma Bruin 3 Loes A.L. van de Pasch 3 Erik H. Rozemuller 3, Khaled Abdelmonen Zaky 4, Marcelo A. Fernández-Viña 51National Cancer Institute, Cairo University, Cairo, Egypt - 2Kasr Alaini School of Medicine & Icahn School of Medicine at Mount Sinai, Egypt - 3GenDx, Utrecht, Netherlands - 4Faculty of Medicine, Azhar university, Egypt - 5Stanford University School of Medicine, Palo Alto, United States of America

P234 ICOS GENE POLYMORPHISMS IN MULTIPLE MYELOMA IN A POLISH POPULATIONAnna Partyka 1, Dariusz Woszczyk 2, Marek Kielbinski 3, Irena Frydecka 1, Lidia Karabon 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2State Hospital, Opole, Poland - 3Medical University, Wroclaw, Poland

P235 ASSOCIATION OF HLA-DRB1*15 ANTIGEN WITH ENDOTHELIAL DAMAGE IN RELAPSING-REMITTING MULTIPLE SCLEROSIS PATIENTSJ. Gonzalo Ocejo-Vinyals 1, Laura Riesco Dávila 1, Vicente González Quintanilla 1, María Toriello Suárez 1, Sara Pérez Pereda 1, Fernando Ausín Ortega 1, Agustín Oterino Durán 11Hospital Universitario Marqués de Valdecilla, Santander, Spain






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P236 GWAS IDENTIFIED STRONG ASSOCIATION OF HLA-DR/DQ WITH CHILDHOOD STEROID-SENSITIVE NEPHROTIC SYNDROME IN THE JAPANESE POPULATIONKatsushi Tokunaga 1, Xiaoyuan Jia 1, Tomoko Horinouchi 2, Yuki Hitomi 1, Akemi Shomo 2, Seik-Soon Khor 1, Yosuke Omae 1, Kaname Kojima 3, Yosuke Kawai 3, Masao Nagasaki 3, Kandai Nozu 2, Kazumoto Iijima 21University of Tokyo, Graduate School of Medicine, Tokyo, Japan - 2Kobe University Graduate School of Medicine, Kobe, Japan - 3Tohoku Medical Megabank Organization, Sendai, Japan

P237 POLYMORPHISMS AND EXPRESSION OF PRO-INFLAMMATORY CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITISJoanna Wielińska 1, Marta Dratwa 1, Jerzy Swierkot 2, Lucyna Korman 2, Monika Chaszczewska-Markowska 1, Barbara Wysoczańska 1, Katarzyna Bogunia-Kubik 31Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Wroclaw Medical University, Wrocław, Poland - 3Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland

P238 KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR AND HLA-C POLYMORPHISMS IN RECURRENT IMPLANTATION FAILUREKarolina Wilzyńska 1, Paweł Radwan 2, Michał Radwan 2, Jacek Wilczyński 3, Andrzej Malinowski 4, Ewa Barcz 5, Rafał Płoski 5, Piotr Kuśnierczyk 1, Izabela Nowak 11Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Gameta Hospital, Rzgów Poland - 3Medical University of Lodz, Łódź, Poland - 4Polish Mothers Memorial Hospital Research Institute, Łódź, Poland - 5Medical University of Warsaw, Warszawa, Poland

P239 HLA HAPLOTYPE DISTRIBUTION AND RISK OF CELIAC DISEASE IN PATIENTS FROM CANTABRIA (NORTHERN SPAIN)Laura Riesco Dávila 1, Fernando Ausín Ortega 1, Marcos López-Hoyos 1, J. Gonzalo Ocejo-Vinyals 11Hospital Universitario Marqués de Valdecilla, Santander, Spain

P240 THE ASSOCIATION OF KIR2DL4, LILRB HAPLOTYPES AND THEIR LIGAND HLA-G WITH ENDOMETRIOSISAleksandra Bylińska 1, Karolina Wilczyńska 2, Andrzej Wiśniewski 2, Jacek Malejczyk 3, Łukasz Milewski 3, Marta Wagner 2, Monika Jasek 2, Wanda Niepiekło-Miniewska 2, Rafał Płoski 4, Ewa Barcz 5, Piotr Roszkowski 6, Paweł Kamiński 7, Andrzej Malinowski 8, Jacek Wilczyński 9, Paweł Radwan 10, Michał Radwan 10, Piotr Kuśnierczyk 11, Izabela Nowak 11

1Politechnika Wrocławska, Wrocław, Poland - 2Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 3Medical University of Warsaw, Warszawa, Poland - 4Department of Medical Genetics, Centre of Biostructure Research, Warszawa, Poland - 5First Chair and Clinic of Obstetrics and Gynecology, Warszawa, Poland - 6Second Clinic of Obstetrics and Gynecology, Warszawa, Poland - 7Department of Gynecology and Gynecological Oncology, Military Medical Institute, Warszawa, Poland - 8Department of Surgical, Endoscopic and Oncologic Gynecology, Łódź, Poland - 9Department of Surgical and Oncological Gynecology, Łódź, Poland - 10Department of Reproductive Medicine, Rzgów Poland - 11Laboratory of Immunogenetics and Tissue Immunology, Wrocław, Poland

P241 INCREASED FREQUENCY OF THE 14-BP INSERTION IN HLA-G Moniek H.C. Craenmehr 1, Iris Nederlof 1, Milo Cao 1, Jacqueline D.H. Anholts 1, Jos J.M. Drabbels 1, Frans H.J. Claas 1, Sebastiaan Heidt 1, Michael Eikmans 11LUMC, Leiden, Netherlands

P242 DIAGNOSTIC TESTING OF HLA-DQ IN CELIAC DISEASEKatarina Stingl Jankovic 1, Danijela Svilicic 1, Marija Maskalan 1, Marija Burek Kamenaric 1, Renata Zunec 1, Zorana Grubic 11University Hospital Centre Zagreb, Zagreb, Croatia



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P243 DISTINCT TYPES OF MYASTHENIA GRAVIS DIFFER BY ASSOCIATION WITH HLA CLASS II ALLELESManuela Testi 1, Giulia Greco 2, Maria Troiano 3, Emanuele Rastelli 2, Eugenio Pompeo4, Giovanni Antonini 5, Marco Andreani 3, Roberto Massa 21San Camillo-Forlanini Hospital, Rome, Italy - 2Neuromuscular Unit, Rome, Italy - 3Laboratory of Immunogenetics and Transplant Biology - IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 4Thoracic Surgery Unit, Rome, Italy - 5Department NESMOS, Rome, Italy

P244 THE CD147 C>G SUBSTITUTION AFFECTS SURVIVAL IN ACUTE MYELOID LEUKAEMIAPiotr Łacina 1, Aleksandra Butrym 2, Grzegorz Mazur 2, Katarzyna Bogunia-Kubik 11Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Wroclaw Medical University, Wrocław, Poland

P245 CRITICAL APPRAISAL ON THE PROGNOSTIC VALUE OF HLA TYPING IN 8 IMMUNE-MEDIATED PATHOLOGIES BASING ON A SERIES OF META-ANALYSESCristina Capittini 1, Marco M. Guarene 1, Chiara Rebuffi 1, Rosalia Cacciatore 1, Annalisa De Silvestri 1, Annamaria A. Pasi 1, Carmine Tinelli 1, Miryam Martinetti 11IRCCS Policlinico San Matteo Foundation, Pavia, Italy

P246 THE ASSOCIATION OF SOLUBLE HLA-G LEVELS AND 3´ UNTRANSLATED REGION HAPLOTYPES OF THE HLA-G GENE WITH THE CLINICAL PROFILE OF EPITHELIAL OVARIAN CANCER PATIENTS REGARDING DISEASE STAGE, CIRCULATING TUMOR CELLS AND OVERALL SURVIVALEsther Schwich 1, Sabine Kasimir-Bauer 2, Rafael T. Michita 3, Hana Guberina 4, Peter A. Horn 1, Rainer Kimmig 2, Paul Buderath 2, Vera Rebmann 11Transfusion Medicine, Essen, Germany - 2Gynecology and Obstetrics, Essen, Germany - 3Genetics Department, Porto Alegre, Brazil - 4Department of Nephrology, Essen, Germany

P247 INFLUENCE OF CYTOKINE GENE POLYMORPHISMS ON HIV INFECTION IN NORTH INDIANSGaurav Sharma 1, Gurvinder Kaur 1, Narinder Kumar Mehra 1, Surendra Kumar Sharma 11All India Institute of Medical Sciences, Delhi, India

P248 ASSOCIATION OF ANXA11 AND TGFB2 GENE VARIANTS WITH PULMONARY SARCOIDOSIS IN THE GREEK POPULATIONAmit Kishore 1, Angeliki Rapti 2, Katerina Sikorova 1, Veronika Zizkova 1, Maria Charikiopoulou 2, Krzysztof Rebala 3, Milan Buc 4, Martin Petrek 51Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic - 2General Hospital for Chest Diseases, Athens, Greece - 3Medical University of Gdañsk, Gdañsk, Poland - 4Faculty of Medicine, Comenius University, Bratislava, Slovakia - 5Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic

P249 IMPLICATION OF HLA CLASS II ALLELES IN CD4/CD8 RATIO NORMALIZATIONKalliroi Tsalimalma 1, Kalliopi Adam 1, Athanasios Kontos 2, Dimitris Maltezas 2, Nikolitsa Kafassi 11General Hospital Athens Laiko, Athens, Greece - 2National University of Athens, Athens, Greece

P250 EVALUATION OF HLA GENOTYPES IN PATIENTS REFERRED FOR CELIAC DISEASE TESTING: A TERTIARY CARE CENTER EXPERIENCEMonika Jain 1, A. Sawhney 1, I. C. Verma 11Sir Ganga Ram Hospital, New Delhi, India






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P251 HLA ASSOCIATED DISEASES. WHAT SHOULD BE ANALYZED?Kirsten Kronenberg 1, Stela Radojska 1, Melanie Stoermer 1, Birgit Gathof 11University of Cologne, Cologne, Germany

MISCELLANEOUSP252 BETA-2-MICROGLOBULIN: A POTENTIAL BIOMARKER FOR BIPOLAR DISORDER AND

SCHIZOPHRENIA?Romain Sayous 1, Céline Manier 1, Nora Hamdani 2, Alix Romier 1, Aparna Sundaresh 1, Christina Mariaselvam 1, Rémi Gadel 3, Céline Hebbache 3, Jean-Romain Richard 3, Marion Leboyer 2, Ryad Tamouza 21Inserm U955, Créteil, France - 2Inserm U955 / FondaMental Foundation / AP-HP, Créteil, France - 3Inserm U955 / FondaMental Foundation, Créteil, France

P253 LACK OF ASSOCIATION BETWEEN THE PROTECTION FROM RED BLOOD CELL ALLOIMMUNIZATION AND HLA-CLASS II VARIANTS IN THE CZECH POPULATIONAlena Maluskova 1, Frantisek Mrazek 2, Renata Kozelska 1, Jitka Rudinska 11Faculty Hospital Ostrava, Ostrava, Czech Republic - 2Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic

P254 IMPROVEMENT OF THE PRIMARY SOURCE FOR MHC SEQUENCING DATA OF NON-HUMAN PRIMATE SPECIES (IPD-MHC NHP 2.0)Natasj G. de Groot 1, Nel Otting 1, Giuseppe Maccari 2, James Robinson 3, Steven GE. Marsh 3, John A. Hammond 2, Ronald E. Bontrop 11Biomedical Primate Research Centre, Rijswijk, Netherlands - 2The Pirbright Institute, Woking, United Kingdom (Great Britain) - 3Anthony Nolan Research Institute, London, United Kingdom (Great Britain)

P255 AN EXTERNAL PROFICIENCY TEST (EPT) FOR SINGLE ANTIGEN FLOW BEAD (SA) ASSAYS ORGANIZED BY THE FRANCOPHONE SOCIETY FOR HISTOCOMPATIBILITY AND IMMUNOGENETICS (SFHI)Isabelle Jollet 1, Jérémy Siemowski 2, Valérie Dubois 3, Nicolas Pignon 1, Elodie Sorin 1, Nicolas Congy 4, Pascale Loiseau 2, Jean-Luc Taupin 21EFS Nouvelle Aquitaine, Poitiers, France - 2Hal Saint Louis, Paris, France - 3EFS Rhône-Alpes, Lyon, France - 4CHU de Toulouse - Faculté de Médecine de Purpan, Université Paul Sabatier Toulouse 3, Toulouse cedex 9, France

P256 WHAT ROLE DOES IL-1BETA CYTOKINE PLAY IN INTELLECTUAL DISABILITY?Anna Aureli 1, Pierluigi Sebastiani 1, Tiziana Del Beato 1, Anna Marimpietri 2, Enzo Sechi 2, Silvia Di Loreto 11Institute of Translational Pharmacology, L’Aquila, Italy - 2University of L’Aquila, ASL n. 4, L’Aquila, Italy

P257 THE ACCURACY OF HFE TESTING IN UK NEQAS FOR H&IS EXTERNAL QUALITY ASSESSMENT SAMPLES 2011-2017Deborah L. Pritchard 1, M T. Rees 11Welsh Transplantation and Immunogenetics Laboratory, Pontyclun, United Kingdom (Great Britain)

P258 HLA POLYMORPHISM AND METHOTREXATE RESPONSES IN SLOVENIAN PATIENTS WITH PSORIASISJasna Grzelj 1, Tanja Gmeiner 2, Pij B. Marko 3, Irena Mlinaric-Rascan 2, Sabina Kunilo-Jamnik 4, Blanka Vidan-Jeras 41Krka, d.d., Novo mesto, Novo mesto, Slovenia - 2University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia - 3Univeristy Medical Centre Maribor, Department of Dermatology, Maribor, Slovenia - 4Blood Transfusion Center of Slovenia, Tissue Typing Center, Ljubljana, Slovenia



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P259 UK NEQAS FOR H&IS EXTERNAL QUALITY ASSESSMENT SCHEME FOR KIR GENOTYPINGDeborah L. Pritchard 1, M T. Rees 11Welsh Transplantation and Immunogenetics Laboratory, Pontyclun, United Kingdom (Great Britain)

P260 CLASSICAL HLA HAPLOTYPE DIVERSITY: A POSSIBLE LINK WITH PRO-INFLAMMATORY PROCESSES IN BIPOLAR DISORDERRyad Tamouza 1, José Oliveira 1, Céline Manier 1, Christina Mariaselvam 1, Aparna Sundaresh 1, Rajagopal Krishnamorthy 1, Dominique Charron 1, Marion Leboyer 11Henri Mondor Hospital, Créteil, France

P261 HD-HLA TYPING: COMPARISON BETWEEN LABTYPE SSO AND HISTO SPOT EXTEND KITSValeria Miotti 1, Chiara Sindici 1, Donatella Londero 1, Vincenzo De Angelis 11ASUIUD, Udine, Italy



Biology (AIBT)







Biology (AIBT)

SPEAKERS - CHAIRSAUTHORS' INDEX






Biology (AIBT)

94

Speakers - ChairsAmit Ido, Rehovot - IsraelAmoroso Antonio, Torino - ItalyAndreani Marco, Roma - ItalyBardy Beatrice, Grenoble - FranceBengtsson Mats, Uppsala - SwedenBlasczyk Rainer, Hannover - GermanyBonini Chiara, Milano - ItalyBontadini Andrea, Bologna - ItalyCarcassi Carlo, Cagliari - ItalyClaas Frans H.J., Leiden - The NetherlandsCozzi Emanuele, Padova - ItalyCucca Francesco, Sassari - ItalyFernández-Viña Marcelo A., Stanford - USAFleischhauer Katharina, Essen - GermanyFoeken Lydia, Leiden - The NetherlandsGourraud Pierre-Antoine, Nantes - FranceGregori Silvia, MIlano - ItalyHarmer Andrea, Sheffield - United KingdomHeinemann Falko, Essen - GermanyHowell Martin, Newcastle - United KingdomHurley Carolyn Katovich, Washington D.C - USAIvanova Milena, Sofia - BulgariaKeskin Derin, Boston - USALatham Katy, London - United KingdomLe Blanc Katarina K., Stockholm - SwedenLegendre Christophe M.F., Paris - FranceLöffler Markus, Tübingen - GermanyLombardi Giovanna, London - United KingdomLombardo Angelo, Milano - ItalyLuznik Leonido, Baltimore - USAMarani Pietro Cesare, Milano - ItalyMarsh Steven G.E., London - United KingdomMartinho Antonio, Coimba - PortugalMascaretti Luca, Trieste - Italy



Biology (AIBT)

95

Mazzi Benedetta, Milano - ItalyMele Lia, Alessandria, ItalyMiotti Valeria, Udine - ItalyMiseferi, Reggio Calabria, ItalyMorelli Adrian E., Pittsburgh - USAMytilineos Joannis, Ulm - GermanyNanni Costa Alessandro, Roma - ItalyNaumova Elissaveta, Sofia - BulgariaPapola Franco, L’Aquilla - ItalyPeacock Sarah Patricia, Cambridge - United KingdomPiazza Antonina, Roma - ItalyQuerol-Giner Sergio Luis, Barcelona - SpainQuintieri Francesca, Roma, ItalyRombolà Giovanni, Firenze, ItalyRoelen Dave L., Leiden - The NetherlandsSacchi Nicoletta, Genoa - ItalySanchez-Mazas Alicia, Genève - SwitzerlandSarwal Minnie M., San Francisco - USASawcer Stephen James, Cambridge - United KingdomSpierings Eric, Utrecht - The NetherlandsSpits Hergen, Amsterdam - The NetherlandsSurendranath Vineeth, Dresden - GermanySüsal Caner, Heidelberg - GermanyTafulo Sandra, Porto - PortugalTesti Manuela, Roma - ItalyTilanus Marcel G.J., Maastricht - The NetherlandsTran Hien, Heidelberg - GermanyTrowsdale John, Cambridge - United KingdomTurner David, Edinburgh - United KingdomVago Luca, Milano - ItalyVillard Jean, Geneva - SwitzerlandVoorter Christien, Maastricht - The NetherlandsWieten Lotte, Maastricht - The Netherlands






Biology (AIBT)

96

Authors' index

AAbad-Molina, Cristina .................................. P21,P24,P162,P207Abatay, Figen ........................................................................ P185Abdel Fattah, Raafat ........................................................ P74,P91Abdrakhimova, Alena R. ....................................................... P169Abdrakhmanova, Saniya .................................................... P7,P61Abdulle, Abdul ........................................................................ P15Acuña-Alonzo, Víctor ............................................................ P184Adam, Kalliopi ....................................................................... P249Affes, Hanen .......................................................................... P170Aggelopoulou, Christina ...................................................... P232Ahn, Kwang Woo .................................................................. P101Akgul, Sebahat U. .................................................. P38,P39,P185Al Baz, Nabeela ........................................................ P13,P14,P80Al Hadra, Bushra ......................................................... P112,P174Al Malki, Monzr ........................................................................ O6Al Suraihi, Osama ............................................................ P14,P80Alba, Francesco ........................................................... P200,P228Albergoni, Maria Paola ........................................................... P88Albers, Joris ........................................................................... P130Alexander, Suceena ................................................................ P62Alfaro, Rafael ................................................................... P18,P63Alizadeh, Mehdi .................................................................... P135Alizzi, Silvia ......................................................................... P6,P58Alkorta, Aitziber ....................................................................... P86Allebes, W.A. ........................................................................... P40Almendral, Jesus ..................................................................... P42Alonso-Rubio, Javier ............................................................. P158Al-Qadi, Rawand ..................................... P158,P159,P160,P187Alter, Idan ............................................................................... O13Alvarez, Cristian M. ................................................................ O44Alvarez, Rafael ....................................................................... P133Alvarez-Lopez, Maria Rocio ........................................ P196,P206Alves, Helena .......................................................................... P44Alzate, Daniel ......................................................................... O44Amato, Antonio ......................................................................... P4Ambrosi, Alessandro .............................................................. O40Ambruzova, Zuzana ............................................................... O30Ameen, Reem ....................................................................... P174

Amirzargar, Ali ....................................................................... P159Amokrane, Kahina ................................................................... P73Amoroso, Antonio ........................................ O8,P6,P58,P60,P65Anagnostouli, Maria .............................................................. P157Anastasiou, Aikaterini...................................................... P8,P156Andersen, Erica ..................................................................... P115Andersen, Menaka ................................................................ P127Anderson, Alison .................................................................... O55Andreani, Marco ..................................... P100,P125,P179,P243Anholts, Jacqueline D.H. ....................................................... P241Anthias, Chloe ........................................................................ O33Antonelli, Antonella ............................................................... O27Antonini, Giovanni ................................................................ P243Antonova, Anzhela .................................................................. P20Antovich, Zachary.................................................................... P45Apostolaki, Maria D. ................................................................ P67Aptsiauri, Natalia ......................................................... P219,P225Aragon, Larraitz ....................................................................... P86Arcese, William ........................................................................ O6Arnaiz Villena, Antonio ......... P148,P158,P159,P160,P186,P187Arnold, Marie-Luise ................................................................... P9Arnold, Renate ....................................................................... O37Arrieta Bolaños, Esteban .................................... O35, P101,P184Artemiadis, Artemios ............................................................ P157Aruldoss, Sam ......................................................................... P62Asaei, Sadaf ........................................................................... P167Askar, Medhat .............................................................. O18,P126Asouhidou, Despoina ........................................................... P156Assanelli, Andrea ................................................................... O40Atanasova, Valentina...................................................... O46,P20Atarod, Sadaf ......................................................................... O38Athanassiades, Theofilos ...................................................... P126Aureli, Anna ....................................................... P203,P231,P256Auriemma, Laura ................................................................... P163Ausín Ortega, Fernando ................................... P230,P235,P239Autolitano, Sara ........................................................... P208,P217Aydin, Filiz ............................................................................... P38Azzaro, Maria Pia ................................................................... P198Azzarone, Raffaella ................................................................ P163



Biology (AIBT)

97

BBaas, M.C. ............................................................................... P40Bacchetta, Rosa ..................................................................... P100Bach, Christian .......................................................................... P9Bade-Doeding, Christina ................................................. O1,O56Bailly, Pascal .......................................................................... P117Baimukasheva, Dana ......................................................... P7,P61Baker, Richard ......................................................................... P41Balas, Antonio ............................................................. P155,P162Baldomero, Helen ................................................................. P103Balen, Sanja ............................................................................. P66Baran, David ............................................................................ P42Barbieri, M. Alejandro ........................................................... P176Barcz, Ewa ......................................................... P229,P238,P240Bardy, Beatrice ........................................................................ P10Barnes, Kathleen .................................................................... O60Barquera, Rodrigo ................................................................. P184Barwell, Jamie ......................................................................... P26Basire, Agnes ..................................................................... P2,P90Batarelo, Mirica ....................................................................... P22Battarra, Mariarosa ................................................................ P125Battle, Richard ........................................................................... P5Bavetta, Rosalba ................................................. P3,P4,P78,P132Bayona, Brayan ..................................................................... P148Beaty, Terri .............................................................................. O60Beecham, Ashley H. ............................................................... O57Beelen, Dietrich W. .......................................................... O6,O35Beelen, Nicky ......................................................................... O26Behzad-Behbahani, Abbas ................................................... P216Bellot, Sidonie ........................................................................ O17Bemelman, F.J. ........................................................................ P40Benecchi, Magda .................................................................... P27Benedek, Gil ........................................................................... O62Benichou, Jennifer ................................................................. O22Bennasar, Florence ............................................................... P135Berardi, Gabriela ................................................................... P107Berg, Randi .............................................................................. P43Bergamaschi, Paola ............................................................... P210Berghella, Anna Maria .......................................................... P231

Berki, Dorrotya ...................................................................... P147Bernal, Monica ...................................................................... P225Berrino, Monica ................................................................. O8,P58Bertaina, Alice ....................................................................... P204Bertinetto, Francesca E. ........................................................... P60Bertol, Bruna C. ....................................................................... P46Bertola, Denise .......................................................................... P1Bertrand, Dominique .............................................................. P68Bessmeltsev, Stanislav .......................................................... P214Betjes, M.G.H. ......................................................................... P40Bhalla, Anil K. .......................................................................... P56Bhargava, Vinant ..................................................................... P56Bianculli, Antonio Giuseppe ................................................... P28Bibby, Louis A. ........................................................................ O38Bicalho, Maria da Graça .......................................................... P46Bickhart, Derek M. ................................................................. P142Biderman, Bella V. ................................................................... P77Binder, Thomas M.C. ......................................... P165,P166,P172Binns-Roemer, Elisabeth .......................................................... O5Biongiovanni, Daniela............................................................. P65Bishara, Amal ........................................................................ P189Blaise, Didier ............................................................................ O6Blancher, Antoine .................................................................. P178Blancho, Gilles ............................................................ P118,P119Blando, Maria ..................................................... P3,P4,P78,P132Blaney, Kathy ................................................................. P92,P114Blasczyk, Rainer .......................................................... O1,O3,O56Bloor, Adrian J. ....................................................................... O33Boasi, Rachel ................................................................. P92,P114Bochenska, Jolanta ................................................................ O29Boffini, Massimo...................................................................... P58Bogacz, Anna .......................................................................... P85Bogunia-Kubik, Katarzyna ................. O64,P16,P218,P237,P244Boix, Francisco ................................................................ P18,P63Bokhari, Ahmad ....................................................... P13,P14,P80Bokos, Ioannis ......................................................................... P67Bolarín, José M. ........................................................... P196,P206Bolcato, Vittorio ..................................................................... P210Boletis, John N. ....................................................................... P67Bologov, Andrey Anatol’evich ................................................. P83






Biology (AIBT)

98

Authors' index

Bonaca, Orjeta ........................................................................ P36Bonda, Avinash ....................................................................... P98Bondanza, Attilio .................................................................... O27Bonini, Chiara ......................................................................... O27Bono, Maria ........................................................................... P204Bontrop, Ronald E. .................... O12,O14,O19,O52,P178,P254Boorer, Linda ........................................................................... P26Bordasco, S............................................................................ P106Bornhauser, Martin ................................................................... O6Borst, Eric ............................................................................... O21Bos, Gerard M. J. ................................................... O25,O26,O28Bosak, Vladimir ..................................................................... P150Bossi, Grazia ........................................................................... O51Boswijk, Kim ............................................................................ P26Bots, M.L. ................................................................................. P40Bottino, Cristina ..................................................................... P204Bottone, Antonio ................................................................... P220Boukla, Anna ................................................................... P8,P156Bourdette, Dennis .................................................................. O62Bouthemy, Charlene ..................................................... P35,P128Bouwmans, Evelien ................................................................ O40Bovo, Daniela .......................................................................... P88Brambilla, Caterina.................................................................... P1Brand-Schaaf, Simone ............................................................ P34Braund, Henny ....................................................................... O33Brautbar, Chaim .................................................................... P189Brazzelli, Valeria .................................................................... P210Brezinova, Dagmar ............................................................... P109Brooks, Andrew G. ............................................................. O2,O4Brouard, Sophie .................................................................... P118Brown, Colin J. .................................................. P134,P136,P144Brown, Juliette ...................................................................... P171Bruijnesteijn, Jesse ................................................................. O52Bruin, Helma ......................................................................... P233Brunet, Nicolino ...................................................................... P90Bruno, Benedetto ............................................................... O6,O8Bruno, Floriana ................................................... P3,P4,P78,P132Bubnova, Ludmila ................................................................. P214Buc, Milan.............................................................................. P248Bucala, Richard ...................................................................... O62

Budde, Klemens ..................................................................... O45Buderath, Paul ....................................................................... P246Buhler, Stéphane ................................................ O34,P103,P179Bukowska, Alicja ...................................................................... P85Bultitude, Will P. ..................................................................... O33Bungener, L.B. ......................................................................... P40Bunjes, Donald ....................................................................... O37Buonomo, Oreste.................................................................. P203Burek Kamenaric, Marija .................. P96,P111,P183,P193,P242Burkitbaev, Zhandos .......................................................... P7,P61Butrym, Aleksandra ............................................................... P244Bykova, Nadezhda A. ............................................................ P116Bylińska, Aleksandra ................................................... P229,P240

CCabrera, Teresa............................................................ P219,P225Cacciatore, Rosalia ...................................................... P210,P245Cafarelli, Silvia ............................................................. P208,P217Cagni, Nicoletta ........................................................................ P1Caillard, Sophie ....................................................................... P47Caillat Zucman, Sophie ........................................................... P73Cailler, Stacy ........................................................................... O57Calafiore, Valeria ................................................................... P198Calantoni, Valeria .............................................. P191,P208,P217Caliskan, Yasar K. .................................................... P38,P39,P185Calýskan, Kader ....................................................................... P89Camisa, Barbara ..................................................................... O27Campillo, José A. ........................................................ P196,P206Campos, Cristina .................. P148,P158,P159,P160,P186,P187Cannavò, Antonino ................................................................. P31Cano, Pedro ........................................................... O15,P92,P114Canossi, Angelica ........................................................ P203,P231Cansever, Murat ............................................................ P75,P151Cao, Milo ............................................................................... P241Caorsi, Cristiana ................................................................. P6,P60Capittini, Cristina ........................................ O31,O51,P191,P245Cappai, Luisella ..................................................................... P228Cappuzzo, Valentina .......................................... P3,P4,P78,P132



Biology (AIBT)

99

Caputo, Flavia ........................................................................... P4Car, Helena .............................................................................. P34Carballo, Ana ......................................................................... P187Carcassi, Carlo ................................................... P199,P200,P228Cárdaba-Arranz, Mario........................................ P24,P162,P207Cardillo, Massimo .............................................................. P1,P31Carey, Sean B. ......................................................................... P26Cargou, Marine ..................................................................... P128Caro, Jose Luis ...................................................................... P155Carvalho-Oliveira, Marco ......................................................... O3Castrillon, Marlon ................................................................... O44Castro-Henriques, António ..................................................... P49Catalano, Manuela ................................................................ P124Cauli, Alberto ........................................................................ P199Cebeci, Egemen ..................................................................... P38Cechova, Hana ...................................................................... P109Cecuk-Jelicic, Esma ............................................................... P192Cekauskiene, Rita .................................................................. P110Celik, Alexander A. ........................................................... O1,O56Cerci Gurbuz, Burcu ...................................................... P17,P213Cereb, Nezih ............................................................... P123,P138Cerna, Marie ............................................................................. O9Cervelli, Carla ................................................................ P76,P163Cesana, Daniela ..................................................................... O27Cesbron, Anne ............................................................ P104,P119Chacko, Mary P. ....................................................................... P19Chalandon, Yves ........................................................... O34,P103Chang, Chia-Jung .................................................................. O11Chang, Chialing ...................................................................... P72Chapova, Regina S. ..................................................... P149,P169Charfi, Aida ........................................................................... P170Charikiopoulou, Maria .......................................................... P248Charron, Dominique ............................................................. P260Chaszczewska-Markowska, Monika ..................................... P237Chatzika, Georgia .................................................................. P156Chechetkin, Aleksandr .......................................................... P214Chen, Qiang ........................................................ P97,P154,P182Chen-Wacker, Chen ................................................................. O3Chernova, Natalia G. ............................................................... P77Chessa, Luchino .................................................................... P228

Chinnadurai, Raj Kumar ........................................................ P215Chmel, Martin .......................................................................... O9Chologitas, Evaggelos ............................................................ P29Chong, Winnie ............................................................ P134,P136Chowdhry, Mohit .................................................................... P32Christiaans, M. ......................................................................... P40Christiansen, Mette ......................................................... P30,P48Christine, Heylen ................................................................... P143Chronis, Theodoros ................................................................... P8Chugreeva, Tamara P. ............................................................ P169Chuva de Sousa Lopes, Susana M. .......................................... O7Ciceri, Fabio ............................................................ O6,O27,O40Cidral, Ana L. ........................................................................... P46Cipri, Selene ...................................................... P199,P200,P228Cirella, Michele ........................................................... P212,P220Claas, Frans H.J. ............. O7,O41,O43,O50,P34,P40,P53,P241Clahsen, Marian C. ................................................................. O43Clark, Andrew ......................................................................... O33Clark, Brendan ........................................................................ P41Claus, Rainer ............................................................................ O6Clekovic, Danijela ................................................................. P183Cocco, Eleonora .................................................................... P200Colacurcio, Vito ..................................................................... P220Colasante, Damiano ............................................................... P28Collin, Matthew ...................................................................... O38COLT ........................................................................... P118,P119Concha, Ángel ...................................................................... P219Condello, Rossella ................................................................ P125Congeddu, Elena ........................................................ P200,P228Congy, Nicolas ...................................................................... P255Connor, Andrew ...................................................................... P26Consortium on Asthma among African-ancestry

Populations in the Americas, (CAAPA) ............................ O60Constantin, Bara .................................................................... P209Contasta, Ida Anna ................................................................ P231Conticello, Etta ...................................................................... P198Corongiu, Daniela ................................................................. P200Corti, Consuelo ...................................................................... O40Coshic, Poonam .................................................................... P222Cossu, Irene ............................................................................ O42






Biology (AIBT)

100

Authors' index

Cox, Steven T. ......................................................................... O53Craenmehr, Moniek H.C. ...................................................... P241Creary, Lisa E. ............................................. O11,O18,P155,P190Crespiatico, Loretta ................................................................... P1Cristian, Tieranu .................................................................... P209Crivello, Pietro .............................................................. O35,P101Crossland, Rachel E. ............................................................... O38Cucca, Francesco ...................................................................... P6Cusano, Roberto ......................................................... P200,P228

Dda Silva Nardi, Fabiola ........................................................... O48Dada, Ashraf ............................................................. P13,P14,P80Dai, Ke-Zheng ....................................................................... P197Dametto, Ennia ....................................................................... P60Damotte, Vincent ................................................................... O57Danby, Robert ................................................................ O33,O53Dandekar, Ravi ....................................................................... O57Daniel, Dolly .................................................................... P19,P62Dantin, Carole ........................................................................ O34Daoudaki, Maria ...................................................................... P29Dapprich, Johannes .................................... O17,O59,O63,P176Dardas, Athanasios ............................................................... P232Darema, Maria ........................................................................ P67Dassa, Sarah ............................................................................ P90D’Auria, Rita ................................................................. P212,P220Davey, Sue ............................................................................ P144Davì, Giuseppe ............................................................ P3,P4,P78David, Gaelle .......................................................................... O49David, Vinoi G. ........................................................................ P62Davis, Kristina A. ...................................................................... P15Daya, Michelle ....................................................................... O60Dayanand, Deo ....................................................................... P42De Angelis, Vincenzo .................................................... P94,P261De Feo, Agata ....................................................................... P212de Fijter, Hans W. ................................................................... O43de Fijter, J.W. ........................................................................... P40de Groot, Nanine .................................................................. P178

de Groot, Natasja G. ................. O12,O14,O19,O52,P178,P254de Hoop, Talitha ..................................................................... O21De Juan, Maria Dolores .......................................................... P86De Sapio, Antonio ................................................................. P212De Silvestri, Annalisa .................................. O31,O51,P191,P245De Silvestro, Giustina .............................................................. P88de Vaal, Yvonne J.H. ............................................................... O41de Vos-Rouweler, Annemiek J. M. ......................................... O52Deaglio, Silvia ............................................................. O8,P6,P65Del Beato, Tiziana.............................................. P203,P231,P256Delgado, Julio ....................................................................... P115Dembowski, Janusz .................................................... P221,P223Demerle, Clémence ................................................................ P90Demir, Erol ..................................................... P38,P39,P59,P185Deplano, Zareen ................................................................... P144Desoutter, Judith................................................................... P188Destro, Roberta ....................................................................... P88Devillier, Raynier ...................................................................... O6Di Cristofaro, Julie ........................................................... P2,P117Di Gregorio, Giancarlo .......................................................... P231Di Loreto, Silvia ..................................................................... P256Di Maio, Paolo ............................................................. P212,P220Di Raimondo, Francesco ....................................................... P198Di, Da...................................................................................... O10Diana, Daniela ....................................................................... P199Dias, Leonídio ......................................................................... P49Dick, Andrea .............................................................................. P9Dickinson, Anne M. ................................................................ O38Didonna, Alessandro ............................................................. O57Digvijay, Kumar ....................................................................... P56Dinou, Amalia .............................................................. O54,P146DIVAT .......................................................................... P118,P119Dogan, Mustafa .................................................................... P120Dolff, Sebastian ...................................................................... O48Donadi, Eduardo A. ................................................................ P46Dongmei, Wang ..................................................................... P71Dorak, Mehmet Tevfik ........................ O17,O59,O63,P120,P176D’Orsogna, Lloyd ................................................................... O50Doss R, Sam A. ........................................................................ P19Douillard, Venceslas .............................................................. P122



Biology (AIBT)

101

Doxiadis, Gaby G.M. .................................................... O52,P178Doxiadis, Ilias .......................................................................... P33Drabbels, Jos J.M. ................................................................. P241Draghi, Eleonora .................................................................... O27Dratwa, Marta ............................................................... O64,P237Dubois, Valérie ...................................................................... P255Dubreuil, Léa .......................................................................... O49Duhovic, Marijana ................................................................... P66Duke, Jamie L. ....................................................................... P115Duquesnoy, Rene J. ................................................................ P54Dutescu, Monica, I. ................................................................ P209Duygu, Burcu .......................................................................... P57Dziopa, Joanna ...................................................................... O36

EEfimov, Grigory A. ................................................................. P116Ehlers, Femke ................................................................. O25,O26Eiermann, Thomas H. ............................................................ P172Eikmans, Michael ......................................................... O43,P241Einsele, Hermann ................................................................... O37Eisner, Sigal ............................................................................. P50El kaaoui El band, Jaouad....................................................... P63Eldem, Asli .................................................................... P17,P211Elferink, Diënne ...................................................................... O52Elfishawi, Mohanad ............................................................... P233Elfishawi, Sally ............................................................... P91,P233Ellinger, Lori .......................................................................... P115Emmi, Giacomo ..................................................................... O31Emonds, Marie-Paule ............................................................ P143Enriquez de Salamanca, Mercedes ...................................... P160Ertan, Serra .................................................................... P39,P185Espadas de Arias, Alejandro ................................................... P31Evgenikaki, Efthimia .............................................................. P156

FFaé, Ingrid ....................................................................... P23,P99

Falco, Michela .............................................................. O42,P204Falkenburg, Frederick ............................................................ O35Farce, Fabienne ....................................................................... P68Fareq Salih, Shadallah ........................................................... P158Farhadi, Ali ............................................................................ P216Farjadian, Shirin............................................................. P81,P216Favero, Roberta ....................................................................... P88Fazio, Maria Rosaria ................................................................ P28Fechtenbaum, Marie ............................................................. P188Felipe, Claudia R. .................................................................... P69Fenici, Lorenza ...................................................................... P124Fernandez Escobar, Nicolas .................................................. P107Fernandez-Viña, Marcelo A.

............................... O11,O18, P126,P155,P180,P190,P233Ferraresso, Mariano................................................................. P31Ferrari-Lacraz, Sylvie ..................................................... O34,P103Ferreira, Virginia ...................................................................... P90Ferreiro, Jose Javier ................................................................ P86Ferriola, Deborah .................................................................. P115Field, Nell ................................................................................ P15Figorilli, Francesco ................................................................ P228Figueiredo, Constanca ............................................................. O3Filkin, Sergey Y. ..................................................................... P116Fingerson, Stephanie ............................................................. O13Finke, Jurgen ............................................................................ O6Finocchi, Martina .................................................................... O31Fischer, Gottfried F. ......................................................... P23,P99Fleischhauer, Katharina ................................ O6,O35,P101,P179Fleva, Alexandra .................................................................... P232Florean, Lara .......................................................................... P124Flores-A, Hilario ........................................................... P190,P201Fogel, Samantha ..................................................................... P15Foster, Ruth ............................................................................. P41Fotoulaki, Maria..................................................................... P232Fouzas, Ioannis ........................................................................ P29Fraboulet, Sterenn................................................................. P135Franceschetto, Genny ............................................................. P88Francone, Marina .............................................. P191,P208,P217Franks, Thomas ........................................................................ P15Frassati, Coralie ......................................................................... P2






Biology (AIBT)

102

Authors' index

Frau, Jessica .......................................................................... P200Froelich, Nadine ...................................................................... P47Frydecka, Irena ........................................ P221,P223,P224,P234Fuhrmann, Markus ................................................................ P121Fürst, Daniel ............................................. O37, P172,P175,P177Fusco, Caterina ...................................................................... P163Füssel, Monika......................................................................... P93Fylaktou, Asimina ..................................................... P8,P29,P156

GGäckler, Anja .......................................................................... O48Gadel, Rémi ........................................................................... P252Gagne, Katia ........................................................................... O49Gaidano, Gianluca ................................................................... O8Galaverna, F. .......................................................................... P106Galenic, Davorka ..................................................................... P22Galian, Jose Antonio ....................................................... P18,P63Gallone, Maria Rita ................................................................ P124Galluccio, Tiziana .................................................................. P100Gambacorta, Valentina .......................................................... O40Gandolfini, Ilaria ...................................................................... P25Gangavarapu, Sridevi .......................................... O11,O18,P155Gaponova, Tatiana V.............................................................. P169Garcia, Aracely ...................................................................... P164Garcia-Alonso, Ana M. ................................................ P196,P206Gariffulin, Andrey .................................................................. P214Garino, Elena ........................................................................... P58Garrido, Federico ........................................................ P219,P225Gathof, Birgit ......................................................................... P251Gatin, Marine........................................................................... P68Gautier Vargas, Gabriella ........................................................ P47Gebura, Katarzyna ................................................................... P16Geerligs, Job ......................................................................... P130Geffard, Estelle ................................ O60,P104,P118,P119,P122Gelens, M. ............................................................................... P40Gendzekhadze, Ketevan .......................................................... O6Geneugelijk, Kirsten ............................................................... O21Gentilini, Ivo .......................................................................... P161

Gentner, Bernard ................................................................... O27Genzano Besso, Federico ........................................................ O8Georgieva, Atanaska .............................................................. O46Gerbase-DeLima, Maria .......................................................... P69Gesheva, Nevena .................................................................... P20Giachino, Daniela F. ................................................................ P65Giannakou, Anastasia ........................................................... P232Giglio, Fabio ........................................................................... O40Gimeno, Lourdes......................................................... P196,P206Giral, Magali ................................................................ P118,P119Giuliodori, Silvia ...................................................................... P27Giuressi, Erika ........................................................................ P199Giustiniani, P. ......................................................................... P106Glatt, Stephen ....................................................................... P180Glavaš-Obrovac, Ljubica ....................................................... P168Gmeiner, Tanja ...................................................................... P258Gnahm, Christine .................................................................. P139Goeb, Vincent ....................................................................... P188Goedert, James J. .................................................................... O5Goeury, Thomas .................................................................... P181Gokarn, Anant ......................................................................... P98Gomez, Carine .......................................................................... P2Gomez-Casado, Eduardo ........................................... P148,P186Gómez-Morales, Mercedes .................................................. P219Gönen, Sevim .......................................................................... P52González Quintanilla, Vicente .............................................. P235González-Ramírez, Amanda Rocío ....................................... P219González, Betsy ........................................................... P190,P201González-Escribano, María Francisca ........................... P24,P155Gonzalez-Fernandez, Rafael ................................................. P155Gonzalez-Martinez, Gema ...................................................... P18Gopalakrishnan, Muralidhar T. ................................................ P51Góralski, Michał ....................................................................... P85Gorodezky, Clara ......................................................... P190,P201Gourraud, Pierre-Antoine.......... O5,O60,P104,P118,P119,P122Gracheva, Liudmila Alexandrovna .......................................... P83Graczyk-Pol, Elzbieta .............................................................. O36Gragert, Loren ........................................................................ O13Gramatzki, Martin ................................................................... O37Grammatico, Paola ................................................................ P124



Biology (AIBT)

103

Gras, Stephanie ...................................................................... O50Grawe, Hanne ....................................................................... P133Greco, Giulia ......................................................................... P243Greco, Raffaella ...................................................................... O40Green, Heftziba ....................................................................... P50Green, Trevor ......................................................................... P144Gregori, Silvia ........................................................................ P100Griskevicius, Laimonas .......................................................... P110Groeneweg, Mathijs ............................................................... O28Gronkowski, Mariusz ............................................................... P85Grubic, Zorana ............... P22,P96,P111,P179,P183,P193,P242Grunz, Fabian ......................................................................... O17Grzelj, Jasna .......................................................................... P258Guarene, Marco .......................................................... P210,P245Guberina, Hana ............................................................ O48,P246Gucyener, Emel ....................................................................... P89Guengoer, Tayfun .................................................................. P103Guerra, Sandra G. ........................................................ P134,P136Guidicelli, Gwendaline.................................................. P35,P128Guillaume, Nicolas ................................................................ P188Guimarães, Tiago ................................................................... O47Gulbas, Zafer ........................................................................... P89Gulec, Derya........................................................ P17,P211,P227Günther, Marie ............................................................. O23,P137Guntz, Philippe ............................................................. P47,P105Gupta, Anurag ......................................................................... P56Gupta, Ashwani ....................................................................... P56Gwozdowicz, Slawomir ................................................ O36,P202

HHaasnoot, Geert W. ........................................................ O43,P53Hack, C.E. ................................................................................ P40Haddad, Rania ........................................................................ P45Halaburda, Kazimierz ............................................................. O36Halagan, Michael ......................................................... O39,P189Halter, Joerg .......................................................................... P103Hamdani, Nora ...................................................................... P252Hamilton-Jones, Siobhan ........................................... P134,P136

Hammond, John A. ................................... O19,P142,P205,P254Hani, Lylia .............................................................................. P215Harpur, Christopher M. ............................................................ O2Harrison, Dorothea ................................................................ P142Hasçuhadar, Medine ............................................................... P89Hau, Françoise ......................................................................... P68Hauer, Vanessa ........................................................................ P46Hauser, Steven L. .................................................................... O57Haverich, Axel .......................................................................... O3Hayhurst, James D. ................................................................ O33Hebbache, Céline ................................................................. P252Heckel, Simon ........................................................................ O32Heidl, Annett ......................................................................... P195Heidt, Sebastiaan ............................ O7,O41,P34,P40,P53,P241Heijmans, Corrine M.C. .................................................. O12,O14Heikkinen-Eloranta, Jenni ...................................................... O58Heim, Dominik ...................................................................... P103Heinemann, Falko M. ............................................... O32,O48,P9Heinold, Andreas ..................................................................... O6Helsen, Philippe ..................................................................... O14Helvacı, Özant ......................................................................... P52Hemmatpour, Shahram ........................................................ P113Henderson, Lorna ..................................................................... P5Hepkema, Bouke G. ................................................................ P40Hernandez, Diana .................................................................. O53Hernandez, Ennio ................................................................. P148Herrero-Mata, Maria Jose ..................................................... P155Heyer, Malte .......................................................................... P133Heyn, Bianca ......................................................................... P195Hiemisch, Wiebke .................................................................. O56Hilbrands, L.B. ......................................................................... P40Hirv, Kaimo ............................................................................ P172Hitomi, Yuki ........................................................................... P236Hò, Gia-Gia T. ........................................................................... O1Hoang, Kevin ............................................................................ O5Höffler, Klaus ............................................................................ O3Hoffmeier, Klaus ..................................................................... O17Hofmann, Jan .............................................................. P139,P173Hoitsma, A.J. ........................................................................... P40Hollenbach, Jill A. ............................................... O57,O60, P195






Biology (AIBT)

104

Authors' index

Höllt, Thomas ........................................................................... O7Hönger, Gideon ...................................................................... P54Honsova, Eva ........................................................................... P11Horinouchi, Tomoko .............................................................. P236Horn, Peter A. ........................................ O6,O32,O35,O48,P246Hösli, Irene .............................................................................. P54House, Justin L. ....................................................................... P70Hrabakova, Pavla ................................................................... P109Hristova, Luisa ........................................................................ O46Hriz, Amal .............................................................................. P170Hsu, Katharine C. ............................................................ O6, P101Hudec, Michael ........................................................................ O9Hughes, Pamela ...................................................................... P41Huyton, Trevor .................................................................. O1,O56

IIandoli, Raffaele .................................................................... P220Ianniello, Alice ......................................................................... P65Iijima, Kazumoto ................................................................... P236Illing, Patricia .................................................................. O50,O55Imbesi, Natale ............................................................. P208,P217Ingrassia, Francesco ........................................... P3,P4,P78,P132Iniotaki, Aliki G. ....................................................................... P67Innocente, Annalisa ........................................................... P1,P31Iozzino, Crystal .............................................................. P,92,P114Irure, Juan........................................................................ P12,P55Isik, Kilicarslan ....................................................................... P185Isildak, Esra .............................................................................. P89Isobe, Noriko .......................................................................... O57Israel, Shoshana .................................................................... P189Israeli, Moshe .................................................................. P50,P95Ivanova Derin, Rayna .............................................................. P73Ivanova, Milena ........................................................... P112,P174Ivanova-Shivarova, Milena ...................................................... P20Iwaszko, Milena ...................................................................... O64

JJackson, Alisa ........................................................................ P129Jaimovich, Gregorio.............................................................. P107Jain, Monika .................................................................. P56,P250Jakovija, Arnolda .................................................................... O27Jakubauskas, Arturas ............................................................ P110Jalali, Sedigheh ..................................................................... P216Jamalidoust, Marzieh ............................................................ P167Jaman, Sonja ......................................................................... P192Janin, Anne ............................................................................ O38Janssen, Johanna W. H. ......................................................... O25Jansson, Katharina ................................................................... O3Jaramillo, Andrés .................................................................... P70Jasek, Monika ....................................................................... P240Jaskuła, Emilia ........................................................................ O29Jeka, Sławomir ............................................................. O64,P218Jensen, Tore .......................................................................... P127Jesani-Hethcoat, Vasnti ......................................................... P144Jia, Xiaoyuan ......................................................................... P236Jie, Wang ................................................................................ P71Jollet, Isabelle ....................................................................... P255Joosten, Irma........................................................................... P40Jopek, Karol ............................................................................ P85Juarez, Ignacio ........................................ P148,P158,P160,P187Jude, John............................................................................... P62Jue, Wang ............................................................................. P182

KKafassi, Nikolitsa ................................................................... P249Kalhs, Peter .............................................................................. P99Kamburova, Elena G. .............................................................. P40Kamel, Hossam ....................................................................... P74Kaminska, Malgorzata ............................................................. P16Kamiński, Paweł..................................................................... P240Kamoun, Arwa ....................................................................... P170Kanagarajah, Abbie R. ............................................................. O2Kandula, Praveen .................................................................... P42



Biology (AIBT)

105

Kandur, Yaşar ........................................................................... P52Kanga, Uma ........................................................................... P222Kannan, Sadhana .................................................................... P98Kapsenberg, Hanneke J.M. ..................................................... O7Karabon, Lidia ......................................... P221,P223,P224,P234Karadeniz Savran, Meltem ...................................................... P59Karahan, Gonca E. .......................................................... O41,P34Karakukcu, Musa ..................................................................... P75Karampatakis, Theodoros ........................................ P8,P29,P156Kasimatis, Efstratios ................................................................... P8Kasimir-Bauer, Sabine ........................................................... P246Katalinic, Natasa ...................................................................... P66Katsavos, Serafeim ................................................................ P157Katsimpoulas, Michalis .......................................................... O54Kaur, Gurvinder ..................................................................... P247Kawai, Yosuke ........................................................................ P236Kedzierska, Katherine............................................................... O2Kekik, Cigdem ........................................................ P38,P39,P185Kelekci, Handan .................................................................... P213Keles, Sevgi ............................................................................. P75Kelsch, Reinhard...................................... P133,P165,P166,P172Kennedy, Amy E. ................................................................... P176Kerick, Martin ........................................................................ P225Kerkhofs, Johan ..................................................................... P143Khamaganova, Ekaterina G. ...................... P77,P108,P149,P169Khamash, Hasan A. ................................................................. P70Khattry, Navin .......................................................................... P98Khor, Seik-Soon ..................................................................... P236Kielbinski, Marek ......................................................... P224,P234Kifle, Sirak .............................................................................. P133Kilicarslan, Isin ......................................................................... P39Kilicaslan Ayna, Tulay ................................. P17,P211,P213,P227Kilicoglu, Murat ................................................. P211,P213,P227Kim, Daehwan ........................................................................ O60Kim, Eunsil ................................................................... P123,P138Kim, Isaac ................................................................................ P45Kim, Sungkyu .............................................................. P123,P138Kimmig, Rainer ...................................................................... P246Kishore, Amit ......................................................................... P248Kitsiou, Vasiliki ....................................................................... P126

Klasberg, Steffen .................................................. O16,O23,P137Klein, Tirza ....................................................................... P50,P95Kleina, Elizaveta .................................................................... P214Kleyman, Lena ......................................................................... P15Klyuchnikov, Dmitry Y. ........................................................... P152Kobbe, Guido ........................................................................... O6Köcher, Stefanie ..................................................................... O17Kocyigit Ozkizilcik, Asli ............................................................ P17Koefoed-Nielsen, Pernille B. .................................... P30,P43,P48Koehn, Corinna B. ................................................................. P172Kojima, Kaname .................................................................... P236Kolasiński, Michał .................................................................... P85Kolesar, Libor................................................................. P87,P147Kolodziej, Anna ........................................................... P221,P223Kolossa, Katarzyna ....................................................... O64,P218Konidari, Ioanna .................................................................... P176Koning, Frits ............................................................................. O7Kontos, Athanasios ................................................................ P249Kooreman, Loes ..................................................................... O26Kooter, Raul ........................................................................... P130Kopic, Kristina.......................................................................... P22Koren, Daniela ......................................................................... P23Korkmaz, Ömer ..................................................................... P120Korman, Lucyna ........................................................... O64,P237Körper, Sixten ........................................................................ P177Kose, Sukran .......................................................................... P227Koster, Johan ........................................................................... P53Kotsimbos, Tom ...................................................................... O50Kouba, Noura .......................................................................... P90Kouniaki, Diamanto............................................................... P126Kountouris, Evan ................................................................... P180Kovacevic Cuculic, Tjasa ......................................................... P66Kovandova, Barbora ............................................................... P11Kozelska, Renata ................................................................... P253Krajewski, Wojciech .................................................... P221,P223Kramer, Cynthia S.M. ....................................................... P34,P53Krammes, Lena ................................................. P165,P166,P172Krasteva, Yana ........................................................................ O46Krezdorn, Nicolas ................................................................... O17Kribben, Andreas ................................................................... O48






Biology (AIBT)

106

Authors' index

Kriegova, Eva ......................................................................... O30Krishnamoorthy, Rajagopal .............................. P215,P226,P260Kroeger, Nicolaus ..................................................................... O6Krom, Debby G.M. ................................................................ P129Kronenberg, Kirsten .............................................................. P251Krop, Juliette .......................................................................... O41Krydel, Michalina ................................................................... O29Ksouda, Kamilia .................................................................... P170Kuba, Adam ........................................................................... O30Kuchmiy, Anna A. .................................................................. P116Kuhn, Joachim.......................................................................... O1Kühnel, Marc ............................................................................ O3Kulikov, Sergey M. ................................................................. P108Kunilo Jamnik, Sabina ................................................. P102,P258Kurtovic, Helena ...................................................................... P66Kuśnierczyk, Piotr .............................................. P229,P238,P240Kuzmina, Larisa A. ................................................................. P108Kuzminova, Elena P. .......................................... P108,P149,P169Kuzminova, Zhanna ................................................................ P82Kwan, Patrick .......................................................................... O55Kwofie, Luyanda Laura .......................................................... P131Kyriacou, Monica................................................................... P144

LLachmann, Nils ............................................................... O24,O45Łacina, Piotr ........................................................................... P244Lai, Sara ....................................................................... P200,P228Laivuori, Hannele ................................................................... O58Lamanna, Roberta ................................................................... P27Lambeck, A.J. .......................................................................... P40Landgraf, Ramona ................................................................... P33Lane, William J. ....................................................................... P45Lang, Kathrin ............................ O16,O20,O23,P137,P139,P173Lange, Andrzej ....................................................................... O29Lange, Janusz......................................................................... O29Lange, Kathrin .......................................................................... O6Lange, Leslie .......................................................................... O60

Lange, Vinzenz ............................. O6,O16,O20,O23,P93,P121, P137,P139,P173,P195

Langer, Mona ......................................................................... O35Lanino, Edoardo .................................................................... P204Lardy, Neubury M.................................................. O52,P40,P129Laserra, Anna Elisa ...................................................... P212,P220Latham, Katy ........................................................................... O33Lattanzio, Roberto ................................................................. P231Lauridsen, Karen B. ................................................................. P48Lazarevic, Dejan ....................................................................... O6Lazar-Molnar, Eszter .............................................................. P115Lazidou, Panagiota ................................................................ P232Leboyer, Marion ...................................... P215,P226,P252,P260Ledoux, Marie-Pierre ............................................................. P105Lee, Jar-How............................................................................ P35Lee, Stephanie J. ................................................................... P101Legaz, Isabel ................................................ P18,P63,P196,P206Legrand, Nolwenn ................................................................. O49Lehmann, Claudia ................................................................... P33Lendrem, Clare ....................................................................... O38Leotta, Salvatore .................................................................... P198Levi, Chen-li ............................................................................. P95Levinson, Douglas ................................................................. P180Li, Chi-Cheng .......................................................................... P72Li, Dongmei ................................................................... P71,P153Li, Jiang ................................................................................. P182Li, Mengdan .................................................................. P97,P154Li, Ming........................................................................ P143,P180Li, Raymond ............................................................................ P45Li, Wei .................................................................................... P153Li, Xingjie ............................................................................... P154Libri, Giuseppe ...................................................................... P217Lidija, Orlic .............................................................................. P66Lima, Bruno A. ......................................................................... P44Limou, Sophie ........................... O5,O60,P104,P118,P119,P122Lin, Chuen-Ying ....................................................................... P72Lin, Jie ...................................................................................... O4Lindemann, Monika ............................................................... O32Lioure, Bruno ......................................................................... P105Litniski, Alexandra .................................................................. O39



Biology (AIBT)

107

Littera, Roberto............................................................ P199,P228Liu, Dongjing ........................................................................ P153Liu, Feiyun ............................................................................... P72Liu, Tommy ............................................................................ P143Lizée, Antoine ........................................................................ O60Llorente, Santiago ........................................................... P18,P63Llull, Cintia ............................................................................. P107Lobato, Luísa ........................................................................... P49Lobo Pereira, Francisco ............................................................ O8Locatelli, Franco .......................................................... P106,P204Lochmann, Evi ....................................................................... P161Loi, Valentina ............................................................... P200,P228Loiseau, Pascale ............................................................ P73,P255Lokki, A. Inkeri ........................................................................ O58Lokki, Marja-Liisa ............................................................ O58,O61Lombardo, Angelo ................................................................. O27Londero, Donatella ....................................................... P94,P261Longa, Lucia ............................................................................ P76Longhi, Elena ............................................................................ P1Lopasso, Aurélie ............................................................ P90,P117López-Hoyos, Marcos .................................. P12,P55,P230,P239Lorenzi, Marco ......................................................................... P76Loundou, Anderson .................................................................. P2Louzoun, Yoram..................................................... O13,O22,O39Lu, Joseph ............................................................................. P129Luiken, Bram ............................................................... P129,P133Lukanov, Tsvetelin .............................................. O46,P112,P174Lupo Stanghellini, Maria Teresa ....................................... O6,O40Lyonnet, Luc .............................................................................. P2

MMabrok, Mazen ....................................................................... P26Maccari, Giuseppe ....................................................... O19,P254Macchiagodena, Mario ............................................................. P1Mack, Steven J. .............................................................. O18,O61MacKinnon, Stephen ............................................................. O33Madbouly, Abeer ......................................................... O39,P189Maddi, Roberta ........................................................... P200,P228

Madrigal, J. Alejandro .......................................... O33,O53,P184Madrigal-Sánchez, Juan José ............................................... P184Magalhães, Maria Conceição ................................................ O47Maggiore, Umberto ................................................................ P25Magistroni, Paola ..................................................... P58,P60,P65Magnan, Antoine ........................................................ P118,P119Mah, Helen .............................................................................. P45Mahaweni, Niken M. ...................................................... O25,O28Mahfoudh, Nadia .................................................................. P170Maiers, Martin ...................................................... O13,O39,P189Maisto, Giovanna .................................................................. P163Majorana, Maria .................................................................... P212Makni, Hafedh ....................................................................... P170Makroo, RN ............................................................................. P32Makrovasili, Fani ............................................................ P29,P156Makushik, Kelsey ..................................................................... P15Malejczyk, Jacek ................................................................... P240Malestein, Remco ................................................................. P145Malheiro, Jorge ....................................................................... P49Malik, Manish .......................................................................... P56Malinowski, Andrzej .......................................... P229,P238,P240Mallempati, Kalyan C. .......................................... O11,O18,P155Mallis, Panagiotis ................................................................... O54Malmberg, Karl-Johan ............................................................. O2Maltezas, Dimitris .................................................................. P249Maluskova, Alena .................................................................. P253Malvezzi, Paolo........................................................................ P10Manetta, Sara ........................................................................... O6Manfreda, Annarita ................................................................. P28Maniangou, Bercelin .............................................................. O49Manier, Céline ................................................... P226,P252,P260Mannarino, Savina ................................................................. O51Mansouri, Marzieh .................................................................. P81Manzo, Antonella ........................................................ P212,P220Marcenò, Raimondo .......................................... P3,P4,P78,P132Marchesani, Marja .................................................................. O61Marchionni, Luigi ..................................................................... O8Marczi, Saška ......................................................................... P168Marget, Matthias ................................................................... P165Mariaselvam, Christina Mary ........................... P226 ,P252,P260






Biology (AIBT)

108

Authors' index

Marimpietri, Anna ................................................................. P256Marin, Luis ............................................................................. P155Marinovic, Ivanka .................................................................. P192Marko, Pij B. ........................................................................... P258Markopoulou, Maria ............................................................. P232Marks, David I. ........................................................................ O33Marrari, Marilyn ....................................................................... P54Marsh, Steven G.E. .................................... O19,O33, P184, P254Martin, Javier ......................................................................... P225Martinetti, Miryam ........................................................ O51,P245Martinez, Natalija .................................................................... P22Martinez-Garcia, Pedro ........................................................... P63Martinez-Gonzalez, Gema ...................................................... P63Martino, Enrica ...................................................................... P198Martinovic-Kaliterna, Duska .................................................. P192Martín-Villa, José Manuel .... P148,P158,P159,P160,P186,P187Martynkevich, Irina ................................................................ P214Marulli, Giuseppe.................................................................. P231Maschan, Alexei ...................................................................... P84Maschan, Michael ........................................................... P82,P84Maskalan, Marija .............................. P96,P111,P183,P193,P242Massa, Roberto ..................................................................... P243Massalski, Carolin .................................................................. P173Masson, Dominique ................................................................ P10Massouridi-Levrat, Stravoula ................................................. P103Maszko-Wodzinska, Iwona .................................................... O29Matern, Benedict M. ............................................................... P57Mathew, Libin .......................................................................... P98Mathias, Rasika ....................................................................... O60Mathow, Daniel ..................................................................... P133Mäurer, André P. .......................................................... P137,P173Mayor, Neema P. .................................................................... O33Mazur, Grzegorz .................................................................... P244Mazzoco, Michela ................................................................. P174Mazzola, Gina A. ..................................................................... P58McCauley, Jacob L. .................................... O57,O59,P120,P176Medina-Pestana, José O. ........................................................ P69Meertens, Christel M.H. .......................................................... P57Mehra, Narinder Kumar ........................................................ P247Meintjes, Peter ...................................................................... P147

Melchiorre, Tiziana .................................................................. P58Melis, Cristina ........................................................................ P200Melis, Maurizio ............................................................ P200,P228Melista, Efi ..................................................................... P87,P147Méndez García, Míguela....................................................... P219Mengozzi, Giulio ..................................................................... P65Mercurio, Manuel .................................................................. P217Merli, P. .................................................................................. P106Merli, Roberta.................................................................. P25,P27Messa, Piergiorgio .................................................................. P31Metzing, Maximilian .............................................................. O35Meulenberg, Pieter ............................................................... P130Meurer, Thuja ......................................................................... O35Meyer, Pieter W. .................................................................... P131Michalopoulos, Efstathios ............................................ O54,P146Michita, Rafael T. ................................................................... P246Middleton, Derek .................................................................. P179Mifsud, Nicole ................................................................ O50,O55Migliara, Alessandro .............................................................. O27Mignot, Emmanuel ............................................................... P180Mihai, Bojinca ........................................................................ P209Mihaylova, Anastasya..................................................... O46,P20Mihaylova, Snezhina .............................................................. O46Mika-Witkowska, Renata ........................................................ O36Mikulic, Mirta ......................................................................... P111Milewski, Łukasz .................................................................... P240Mindrinos, Michael ............................................................... P180Mine, Karina L. ......................................................................... P69Mingari, Maria Cristina ........................................................... O42Minguela, Alfredo ........................................ P18,P63,P196,P206Miotti, Valeria ................................................................ P94,P261Mircea, Diculescu .................................................................. P209Mishra, Manoj ......................................................................... P32Misra, Maneesh K. .................................................................. O57Mistretta, Serena ................................................ P3,P4,P78,P132Mittal, Siddharth .............................................................. P19,P62Mlinaric-Rascan, Irena ........................................................... P258Mohapatra, Anjali .................................................................... P62Mohty, Mohamad .................................................................... O6Molenbroeck, Stefan .............................................................. O28



Biology (AIBT)

109

Møller, Bjarne K. ...................................................................... P30Monos, Dimitri ...................................................................... P115Montanari, M. ........................................................................ P106Montanič, Sendi .................................................................... P102Montero-Martin, Gonzalo ............................................ O11,P155Montesu, Maria Antonietta ................................................... P199Montini, Eugenio ................................................................... O27Monzón, David ........................................................................ P86Mor, Eytan ............................................................................... P50Morath, Christian .................................................................... O44Moreira-Espinoza, María José .............................................. P184Moretta, Alessandro .............................................................. P204Moretta, Lorenzo .......................................................... O42,P204Morikone, Pablo .................................................................... P107Moscetti, Alessandra ............................................................. P124Moschini, Pamela M. .......................................... P6,P58,P60,P65Mossallam, Ghada ........................................................ P74,P233Mounsey, Katherine ................................................................ P41Mourão, Tuíla B. ....................................................................... P69Mourya, Manish .................................................................... P222Moussa, Omar ......................................................................... P15Moya-Quiles, Maria R. ........................ P18,P63,P155,P196,P206Mratinovic-Mikulandra, Jela ................................................. P192Mrazek, Frantisek ......................................................... O30,P253Müberra, Ahci........................................................................... O6Mulder, Wietse ....................................................................... O40Mulgaonkar, Shamkant ........................................................... P42Munguia, Andrea ........................................................ P190,P201Muñiz, Ester .......................... P148,P158,P159,P160,P186,P187Muro, Manuel ..................................... P18,P63,P155,P196,P206Murru, Roberta ...................................................................... P200Mytilineos, Joannis ................................... O37,P172,P175,P177

NNagasaki, Masao ................................................................... P236Nagler, Arnon ........................................................................... O6Nagy, Marion.......................................................................... O17Nagy, Nora ............................................................................ P147

Nair, Gayathri ........................................................................ P103Namayandeh, Mandana ....................................................... P167Nane, Ismet ............................................................................. P59Naper, Christian .................................................................... P197Nareiko, Maria V. ..................................................................... P77Nasilowska-Adamska, Barbara .............................................. O36Naumova, Elissaveta ................................... O46,P20,P112,P174Navaretti, Elena ....................................................................... P60Navarrete, Cristina V. ................................................... P134,P136Nederlof, Iris .......................................................................... P241Nedilakova, Antoaneta ............................................... P112,P174Negi, Vir Singh ............................................................ P215,P226Nelson, George ........................................................................ O5Nelson, Lora J. ......................................................................... P70Nesher, Eviatar ........................................................................ P50Nestorowicz, Klaudia ................................................... O36,P202Neuchel, Christine .................................... O37,P172,P175,P177Nguyen, Thi H.O. ...................................................................... O2Nickman, Hosein ................................................................... P159Nicoloso, Grazia .................................................................... P103Niederwieser, Dietger ............................................................ O37Niemann, Matthias ................................................. O24,O45,P54Nieminen, Markku S. .............................................................. O61Niepiekło-Miniewska, Wanda ....................................... P16,P240Nieszporek, Artur .................................................................... P16Nieto, Antonio ......................................................................... P21Nieto, Jorge ...................................................... P158,P160,P187Nikbin, Behrouz .................................................................... P159Nikolaidou, Vasiliki .................................................................... P8Niokou, Dimitra ..................................................................... P144Nocco, Angela .......................................................................... P1Nocito-Colón, Mercedes....................................................... P207Nong, Thoa ............................................................................. P35Norden, Jean ......................................................................... O38Norman, Paul J. ..................................................................... P195Notaro, Ilaria ............................................................................ P65Novelli, Giorgio ..................................................................... P203Nowak, Izabela .................................................. P229,P238,P240Nowak, Jacek ............................................................... O36,P202Nozu, Kandai ......................................................................... P236






Biology (AIBT)

110

Authors' index

Nunes, José Manuel ................................ O10, P103,P179,P181Nurmohamed, A. .................................................................... P40

OOcejo-Vinyals, J. Gonzalo ....................... P155,P230,P235,P239Offner, Halina ......................................................................... O62Oguz Savran, Fatma ....................................... P38,P39,P59,P185Oksenberg, Jorge R. ...................................................... O57,O62Olagne, Jerôme ...................................................................... P47Olbromski, Krzysztof ............................................................... P85Olieslagers, Timo I.................................................................. O28Olivares, Ivan Rivas ................................................................ O28Olivares, Nerea........................................................................ P86Olivas-Martínez, Israel ............................................................. P24Oliveira, Giacomo .................................................................. O27Oliveira, Jeffrey ...................................................................... O12Oliveira, José Gerardo ................................ O47,P37,P215,P260Olivia, Popa M. ...................................................................... P209Ollila, Hanna.......................................................................... P180Omae, Yosuke ....................................................................... P236Onali, Simona........................................................................ P228Onnis, Giuliana...................................................................... P199Onozawa, Masahiro ................................................................. O6Ontañón-Rodríguez, Jesús ................................................... P207Opelz, Gerhard ...................................................................... O44Orchard, Kim ......................................................................... P113Orduña-Domingo, Antonio ........................................ P162,P207O’Reilly, Steven ...................................................................... O38Órlich-Pérez, Priscilla ............................................................. P184Orrù, Nicola ........................................................................... P199Orrù, Sandro................................................................ P199,P228Osoegawa, Kazutoyo ........................................... O11,O18,P126Oterino Durán, Agustín ......................................................... P235Otten, H.G. .............................................................................. P40Otting, Nel.................................................. O19,O52,P178,P254Ottonello, Selene ................................................................... O42Özbek, Umut ......................................................................... P176Ozcan, Alper ........................................................................... P75

Ozel, Leman ............................................................................ P89Ozkizilcik Kocyigit, Asli ................................................ P211,P213Ozluk, Yasemin .............................................................. P39,P185Ozzella, Giuseppina ................................................................ P28

PPadros, Karin ................................................................. P79,P107Pagliuca, Antonio ................................................................... O33Pakos, Helena ......................................................................... O29Palacio-Gruber, Jose ............ P148,P158,P159,P160,P186,P187Palfi, Biserka ............................................................................ P22Palumbo, Carmela................................................................. P217Papachristou, Marianthi ..................................................... P8,P29Papagianni, Aikaterini ............................................................... P8Papapanagiotou, Aggeliki ..................................................... O54Papola, Franco ............................................................... P76,P163Parakh, Shilpa ........................................................................ P129Paredes-Carias, Edel ............................................................. P184Parga Lozano, Carlos H. ........................................................ P164Parisi, Marina ......................................................................... P198Parissiadis, Anne ........................................................... P47,P105Parkinson, Andrea ................................................................... P15Parlavecchio, C. ..................................................................... P106Parolini, Riccardo.................................................................... O40Parovichnikova, Elena N. ....................................................... P108Parren, Paul W.H.I. ................................................................... P34Partyka, Anna ........................................... P221,P223,P224,P234Pasi, Annamaria A. ............................................. O51,P210,P245Paskalev, Emil ......................................................................... O46Passamonti, Serena Maria ....................................................... P31Passweg, Jakob ..................................................................... P103Pasvoski, Oren ......................................................................... P95Patiroglu, Turkan ............................................................ P75,P151Paul, Pascale .............................................................................. P2Pavlatova, Lucie ..................................................................... P109Pavlova, Anastasia ................................................................. P214Pavlova, Irina ......................................................................... P214Pawliczak, Daria ..................................................................... O36



Biology (AIBT)

111

Pearce, Kim F. ......................................................................... O38Peccatori, Jacopo ............................................................. O6,O40Pedersen, Alice P. .................................................................. P127Pegova, Kristyna .................................................................... P109Peitsch, Cory ............................................................................ P15Pelardy, Matthieu ...................................................................... P2Pellegrini, Patrizia .................................................................. P231Pende, Daniela ...................................................................... P204Penickova, Sona .................................................................... P150Penning, Maarten T. ................................ P129,P130,P141,P145Penta de Vera Aragona, Roberta .......................................... P163Perea, Francisco .......................................................... P219,P225Pérez Pereda, Sara ................................................................. P235Pérez-Escobar, Oscar A. ......................................................... O17Perola, Markus ........................................................................ O61Perotti, Laura ........................................................................... P76Perrone, Francesco .................................................................. P60Perrot, Eric ............................................................................. P135Perry, Julia .............................................................................. O33Peter, Wolfgang ................................................ P165,P166,P172Petrek, Martin ..................................................... O30,P168,P248Petrillo, Marika ............................................................. P212,P220Petrova, Larisa Vladimirovna ................................................... P83Phieler, Julia .......................................................................... P121Piazza, Antonina ...................................................................... P28Piazza, Bruna ............................................................................. P3Picard, Christophe .......................................... P2,P90,P117,P135Picardi, Alessandra ................................................................... O6Piccolo, Adriana .................................................................... P210Pidala, Joseph ....................................................................... P101Pietra, Gabriella ................................................................ O2,O42Pignon, Nicolas ..................................................................... P255Pilunov, Artem M. .................................................................. P116Pinana, Jose L. .......................................................................... O6Pinelli, David ........................................................................... P51Pini, Massimo ........................................................................... O6Pino-Yanes, Maria ................................................................... O60Pinto, R. M. ............................................................................ P106Piovano, Federica .................................................................... P76Pitzalis, Maristella ...................................................................... P6

Pizzochero, Cinzia ................................................................. P210Plaisier, L. ................................................................................. P40Planelles, Dolores ................................................................. P155Plesec, Eva ............................................................................... P36Płoski, Rafał ................................................................. P238,P240Poggi, Elvira............................................................................. P28Poirier, Nicolas....................................................................... P178Poles, Ann .............................................................................. P115Poles, Anthony ........................................................................ P26Poli, Francesca ......................................................................... P31Pompeo, Eugenio ................................................................. P243Pons, Jose A. ........................................................................... P18Porcella, Rita ................................................................ P200,P228Potter, Michael N. ................................................................... O33Potter, Victoria T. ..................................................................... O33Poyraz, Aykut ......................................................................... P151Prerovska, Renata .................................................................. P109Pristanskova, Ekaterina Andreevna ......................................... P83Pritchard, Deborah L. ........................................ P140,P257,P259Profaizer, Tracie ..................................................................... P115Prucca, Maristella .................................................................... P76Pruschke, Jens ............................................................. P139,P173Puchala, Marta ....................................................................... P218Puglisi, Fabrizio ..................................................................... P198Punatar, Sachin ........................................................................ P98Purcell, Anthony ............................................................. O50,O55Pymm, Philip ............................................................................ O4

QQiu, Yan ................................................................................. P153Quin, Lyudmila ...................................................................... P112

RRabbi, Sikder N.I. .................................................................. P165Rachamimov, Ruth .................................................................. P50Radojska, Stela ...................................................................... P251






Biology (AIBT)

112

Authors' index

Radwan, Michał ........................................................... P238,P240Radwan, Paweł ............................................................ P238,P240Rafaels, Nicholas .................................................................... O60Rafiei-Dehbidi, Gholam-Reza ............................................... P216Ragatzu, Paola ................................................... P199,P200,P228Raida, Ludek ........................................................................... O30Rajadhyaksha, Sunil ................................................................ P98Rajkumar, Ravi Philip ................................................... P215,P226Ralazamahaleo, Mamy .................................................. P35,P128Ramilyeva, Indira ................................................................ P7,P61Ramirez, Maria ........................................................................ P15Ramirez, Yasmill ..................................................................... P114Ramondetta, Miriam ................................................................. P1Rampim, Gisele F. ................................................................... P69Rampoldi, Luca ....................................................................... P65Ramzi, Mani ............................................................................. P81Rana, Devinder S. .................................................................... P56Rao, Prakash ............................................................................ P42Rapti, Angeliki ....................................................................... P248Rastelli, Emanuele ................................................................. P243Ratajczak, Philippe ................................................................. O38Raykina, Elena ................................................................. P82,P84Rebala, Krzysztof ................................................................... P248Rebmann, Vera ............................................................. O48,P246Rebuffi, Chiara....................................................................... P245Rees, M.T. .......................................................... P140,P257,P259Reinders, Marlies E.J. ............................................................. O43Retiere, Christelle ................................................................... O49Rey, Diego ............................................................................. P159Reynaud-Gaubert, Martine ....................................................... P2Richard, Jean-Romain ........................................................... P252Richardson, Debbie .............................................................. P113Ridgley, Rose M. ..................................................................... P70Riesco, Laura ...................................... P12,P55,P230,P235,P239Rihova, Adela ........................................................................... O9Rijnaard, Hans J.H.A. .............................................................. O12Ripaldi, Mimmo..................................................................... P163Robinson, James .................................................. O19,O33,P254Rocchi, Lorenzo ....................................................................... P60Rodrigo, Emilio ............................................................... P12,P55

Rodriguez, Joshua M. ............................................................. P45Rodriguez, Maria Beatriz ............................................... P79,P107Roelen, Dave L. ............................................... O41,P34,P40,P53Rogatko-Koros, Marta ............................................................ O36Rojewski, Markus................................................................... P177Romagnoli, Renato ................................................................. P60Romaniuk, Dmitry S. ............................................................. P116Romano, Alessandra ............................................................. P198Romeo, Giuseppa ............................................. P191,P208,P217Romier, Alix ........................................................................... P252Roncarolo, Maria Grazia ........................................................ P100Roozendaal, C. ........................................................................ P40Rossjohn, Jamie ....................................................................... O4Rosso, Claudia Maria ................................................................ P6Rostaing, Lionel....................................................................... P10Roszkowski, Piotr ................................................................... P240Rotar, Katja .............................................................................. P36Roth, Tobias ....................................................... P165,P166,P172Rothe, Jessica ......................................................................... O17Rowntree, Louise .................................................................... O50Rozemuller, Erik H. .................................. P130,P141,P145,P233Ruczinski, Ingo ....................................................................... O60Rudd, Stephen ....................................................................... O17Rudinska, Jitka ...................................................................... P253Ruiz-Cabello, Francisco ............................................... P219,P225Ruiz-del-Valle, Valentín ......................................................... P186Ruiz-San Millán, Juan Carlos ................................................... P12Russell, Nigel H. ..................................................................... O33Russnak, Roland ...................................................................... P45Ruzius, Frans-Paul .................................................................. P130Ryu, Jaejun ............................................................................ P138

SSacchi, Nicoletta ................................................................... P174Saduakas, Zhazira .............................................................. P7,P61Sage, Deborah A. .................................................................. P113Saglio, Giuseppe ...................................................................... O8Saif, Imran S. ............................................................................ P26



Biology (AIBT)

113

Saladino, Rita E.................................................. P191,P208,P217Salazar-Sánchez, Lizbeth ...................................................... P184Sali, Vera ................................................................................ P194Salizzoni, Mauro ...................................................................... P60Salomaa, Veikko ..................................................................... O61Salvadori, Filomena .............................................................. P217Salzberg, Steven .................................................................... O60Samardžija, Marina ............................................................... P168Sampaio-Norton, Susana ............................................... O47,P37San Segundo, David ....................................................... P12,P55Sánchez, Guadalupe ............................................................. P201Sanchez-Garcia, Florentino ................................................... P155Sanchez-Gordo, Francisco .................................................... P155Sanchez-Mazas, Alicia ............................... O10,P103,P179,P181Sánchez-Palencia, Abel ............................................... P219,P225Sanders, J.S.F. ......................................................................... P40Santaniello, Adam .................................................................. O57Santaniello, Francesco ........................................................... O27Sanz, Guillermo ........................................................................ O6Sanz, Jaimie ............................................................................. O6Sarkar, Subhashis ................................................................... O25Sathananthan, Thusa ............................................................. P144Satta, Rosanna ....................................................................... P199Saudemont, Aurore ................................................................ O53Saunders, Philippa M. .............................................................. O4Sauter, Jürgen ................................................... P139,P173,P195Savchenko, Valeriy G. .......................................... P77,P108,P169Savran Oguz, Fatma ................................................................ P89Sawhney, A. ........................................................................... P250Sayno, Jex-Ray ....................................................................... O33Sayous, Romain ..................................................................... P252Sbarsi, Ilaria ........................................................................... P210Schäfer, Marco .................................................. P165,P166,P172Schaffer, Brian .......................................................................... O6Schall, Cynthia ......................................................................... P15Schanz, Urs ............................................................................ P103Schaub, Stefan ........................................................................ P54Schauss, Debra ....................................................................... P15Schefzyk, Daniel .......................................................... P139,P173Scherdel, Pauline......................................................... P118,P119

Schetelig, Johannes ................................................................ P93Schirru, Lucia ......................................................................... P200Schmidt, Alexander H.

......... O6,O16,O20,O23,P93,P121,P137,P139,P173,P195Schneiderova, Petra ............................................................... O30Schoene, Bianca.................................................................... P139Schöfl, Gerhard .......................... O16,O20,O23,P93,P121,P137Schoina, Maria .......................................................................... P8Schöne, Bianca ...................................................................... P121Schönemann, Constanze ....................................................... O45Schrezenmeier, Hubert ...................................... O37,P175,P177Schwartz, John C. ........................................................ P142,P205Schwich, Esther ..................................................................... P246Sconocchia, Giuseppe .......................................................... P203Sebastiani, Pierluigi ............................................................... P256Sechi, Enzo ............................................................................ P256Secinaro, Enzo ....................................................................... P231Sedzimirska, Mariola .............................................................. O29Seelen, M.A.J. ......................................................................... P40Seitz, Adrienne ........................................................................ P41Sekerkova, Zuzana .................................................................. P11Sela-Navon, Michal ................................................................. P95Semana, Gilbert .................................................................... P135Senev, Aleksandar ................................................................. P143Senturk Ciftci, Hayriye ............................................................. P59Serra, Anna ............................................................................... O8Serra, Maria ................................................................. P200,P228Serrano-Vela, Ignacio ............................................................ P186Serventi Seiwerth, Ranka ...................................................... P111Seshadri, Vijayaragavan .............................................. P123,P138Sever, Mehmet S. .......................................................... P39,P185Sgobba, Valentina ................................................................... P27Shan, Xiaoyan .......................................................................... P71Shargian, Liat........................................................................... P95Sharma, Gaurav ..................................................................... P247Sharma, Surendra Kumar ...................................................... P247Sharma, Vandana .................................................................... P32Shaw, Bronwen E................................................ O33,P101,P184Sheetikov, Savely A. .............................................................. P116Shivarov, Velizar .................................................................... P174






Biology (AIBT)

114

Authors' index

Shomo, Akemi ....................................................................... P236Shragina, Olga ................................................................ P82,P84Sidira, Evangelia .................................................................... P156Siebert, Nicole ....................................................................... P166Siemowski, Jérémy ............................................................... P255Siffnerova, Vera ....................................................................... P87Sikorova, Katerina ....................................................... P168,P248Silhova, Elena ........................................................................... O9Silva, Selma D. ......................................................................... P98Silvera, Carlos ........................................................................ P148Silvestri, Elena ........................................................................ O31Silvy, Monique ....................................................................... P117Simac Susanj, Ines ................................................................... P66Simmons, Gregory .................................................................. P15Simon, Sophie ......................................................................... P90Simper, Gwendolin S. ...................................................... O1,O56Sindici, Chiara ....................................................................... P261Singh, Mandhata ..................................................................... P32Singh, Meenakshi.................................................................... P98Singh, Sandeep K. ................................................ O59,O63,P176Sinisalo, Juha ................................................................. O58,O61Sinopoli, Silvia ......................................................................... P28Sioli, Viviana .............................................................................. P1Siorenta, Alexandra A. ............................................................. P67Skalisz, Hanna ......................................................................... P85Skorobogatova, Elena Vladimirovna ...................................... P83Skoumi, Dimitra A. .................................................................. P67Slavcev, Antonij ....................................................................... P11Smith, Tim P.L. ....................................................................... P142Smits, Marjolein ..................................................................... O26Soonawala, Darius ................................................................. O43Sorin, Elodie .......................................................................... P255Sortino, Grazia ....................................................................... P198Sotiriadou, Fotini ................................................................... P232Sowiński, Mateusz ................................................................... P85Söylemezoğlu, Oğuz .............................................................. P52Soyoz, Mustafa ........................................... P17,P211,P213,P227Sözen, Hakan .......................................................................... P52Spano, Lucia ............................................................................ P28Spellman, Stephen................................................................ P101

Spierings, Eric ................................................ O21,O24,O45,P40Spriewald, Bernd M. ................................................................. P9Spruyt-Gerritse, Marijke J. ...................................................... O43Spyropoulou-Vlachou, Maria ....................................... O54,P146Stacey, Sara ............................................................................. P26Staeck, Oliver ................................................................. O24,O45Stankova, Martina ................................................................. P109Stavropoulos-Giokas, Catherine .................................. O54,P146Steckel, Nina K. ........................................................................ O6Štefanić, Mario ...................................................................... P168Stein, Jeremy E. ..................................................................... P184Stein, Jerry ............................................................................... P95Stempelmann, Karin ................................................................ O6Steri, Maristella .......................................................................... P6Stevens, Jeroen M.G. ............................................................. O14Stingl Jankovic, Katarina .................. P96,P111,P183,P193,P242Stoermer, Melanie ................................................................. P251Stoll, Scott ............................................................................... P70Stölzel, Friedrich ....................................................................... O6Stranges, Alessia ................................................................... P217Strano, Aurora ......................................................................... P88Stratta, Piero ............................................................................. O8Studer-Bettens, Florence ....................................................... O34Stupniko, Aleksei ...................................................................... O8Sudarikov, Andrey B. ............................................................... P77Sullivan, Lucy C. ............................................................... O2,O42Sundaresh, Aparna.................................. P215,P226,P252,P260Sürel, Ö. Orkun ...................................................................... P120Surendranath, Vineeth ................................................. O20,P121Süsal, Caner ........................................................................... O44Suslova, Tatiana A. ................................................................. P152Svetec, Magdalena ................................................................. P22Svilicic, Danijela .......................................................... P193,P242Swelsen, Wendy T. ................................................ O52,P40,P129Świerkot, Jerzy ................................................... O64,P218,P237Szczepinski, Andrzej .............................................................. O36Szlendak, Urszula ......................................................... O36,P202Szydlo, Richard M................................................................... O33



Biology (AIBT)

115

TTafulo, Sandra .......................................................................... P49Talal, Chatila ............................................................................ P75Tambe, Manisha ...................................................................... P98Tambur, Anat R. ....................................................................... P51Tamouza, Ryad ........................................ P215,P226,P252,P260Tandoi, Francesco ................................................................... P60Tandon, Nikhil ....................................................................... P222Tang, Ruoping .......................................................................... O6Tarassi, Katerina ..................................................................... P126Taub, Margaret ....................................................................... O60Taupin, Jean-Luc ........................................................... P35,P255Tavarozzi, Franco .................................................................... O33Tavkin, Elena .......................................................................... P129Tedeschi, Sara ......................................................................... P25Tedesco-Silva, Hélio ................................................................ P69Tefik, Tzevat ............................................................................. P59Temurhan, Sonay ................................................... P38,P39,P185Ten Berge, I.J.M. ...................................................................... P40Teshima, Takanori ..................................................................... O6Testa, Giuseppe..................................................................... P125Testi, Manuela ................................................... P124,P125,P243Tetar, Gayatri C. ..................................................................... P129Thakur, Yogita .......................................................................... P32Thomas, Pascal .......................................................................... P2Thomson, Kirsty J. .................................................................. O33Tielens, Kaat ........................................................................... O12Tieranu, Ioana ........................................................................ P209Tiercy, Jean-Marie ................................................................. P103Tilanus, Marcel G.J. ................................ O25,O26 O28,P40,P57Tinelli, Carmine .......................................... O31,O51,P191,P245Tissot, Adrien ............................................................... P118,P119Todaro, Sonia ........................................................................... O6Toffalori, Cristina............................................................... O6,O40Tokić, Stana ........................................................................... P168Tokunaga, Katsushi ............................................................... P236Tomaszewska, Agnieszka ....................................................... O36Tomkiewicz, Anna ....................................................... P221,P223Tomoya Michita, Rafael .......................................................... O48

Topcu, Sinem......................................................................... P213Torgerson, Dara ...................................................................... O60Toriello Suárez, María ............................................................ P235Toriello, Mario ....................................................................... P163Torres, Franklin ...................................................................... P164Toscanini, Ulises ............................................................ P79,P107Toscano, Sebastiana.............................................................. P198Tranquilli, Stefania ................................................................. P200Trilling, Mirko .......................................................................... O48Troiano, Maria........................................................................ P243Trojok, Peter ........................................................................... P166Trucas, Marcello .................................................................... P228Trunecka, Pavel ........................................................................ P11Trusova, Larisa M. .................................................................. P152Tsalimalma, Kalliroi ................................................................ P249Tsamadou, Chrysanthi........................................ O37,P175,P177Tsirogianni, Alexandra ........................................................... P126Tsuang, Ming ......................................................................... P180Turazzi, Nice ........................................................................... O27Turganbekova, Aida ........................................................... P7,P61Turiano, Francesco ................................................................ P208Turkmen, Aydin ...................................................... P39,P59,P185Turnbull, Angus ......................................................................... P5Turner, David M. ........................................................................ P5Turner, Thomas R. ................................................................... O33Tyumina, Olga V. ................................................................... P152

UUçan, Gulsah ........................................................................... P75Ulman, Maayan ........................................................................ O6Unal, Ekrem ............................................................................. P75Uyar-Mercankaya, Merve ......................................................... O7

VVaage, John Torgils ............................................................... P197Vago, Luca ............................................................... O6,O27,O40






Biology (AIBT)

116

Authors' index

Valatkaite-Rakstiene, Beatrice ............................................... P110Valencia, Miriam.................................................................... P201Valentini, Maria Donatella..................................................... P228Valhova, Sarka ......................................................................... P11van Balen, Peter...................................................................... O35van de Pasch, Loes A.L. ..................................... P141,P145,P233van den Heuvel, Heleen ......................................................... O50van der Boog, P.J.M. ............................................................... P40van der Hoorn, Marie-Louise P. ................................................ O7van der Meer, A. ...................................................................... P40van der Pant, K.A.M.I. .............................................................. P40van der Weerd, N.C................................................................. P40Van der Wiel, Marit K.H. ............................................... O52,P178van der Zwan, Anita ................................................................. O7van Deutekom, Hanneke W.M. ................................... P130,P141van Duijnhoven, E. .................................................................. P40van Gelder, Michel ................................................................. O26van Ham, Karin ...................................................................... P141van Heck, Michelle ................................................................ P145van Ittersum, F. ........................................................................ P40Van Kooten, Cees .................................................................... P34Van Laar, Jacob M. ................................................................. O38van Reekum, F. ........................................................................ P40Van Sandt, Vicky .................................................................... P143van Unen, Vincent .................................................................... O7van Wageningen, Sake ............................................... P129,P133van Zuilen, A.D. ....................................................................... P40Vandenbark, Arthur A. ............................................................ O62Vanegas-Padilla, Yondra ....................................................... P184Varughese, Santosh ................................................................ P62Vasyukov, Konstantin V. ......................................................... P169Vavilov, Mikhail N. ................................................................. P152Vayntrub, Tamara ......................................................... O11,P155Vecchiato, Cinzia ................................................................... P161Vega, Maria Igea ................................................ P3,P4,P78,P132Velier, Mélanie ........................................................................ P90Vendelbosch, Sanne ............................................................. P141Verduci, Anna Maria .................................................... P208,P217Verhaar, M.C. ........................................................................... P40Verite, Franck ......................................................................... P135

Verma, I. C. .................................................................... P56,P250Verneris, Michael R. ............................................................... P101Verosimile, Mattia ................................................................. P220Verzijl, Cristy ........................................................................... O12Viard, Thierry ........................................................................... P45Vicario, Jose Luis ......................................................... P155,P162Vidan-Jeras, Blanka ............................................. P36,P102,P258Viken, Marte K. ...................................................................... P127Vilches, Carlos ....................................................................... P155Vilches-Moreno, Miriam ......................................... P21,P24,P207Villard, Jean ........................................................... O34,P81,P103Vince, Nicolas ............................ O5,O60,P104,P118,P119,P122Vinti, Valentina .......................................................................... P4Visentin, Jonathan ......................................................... P35,P128Vitale, Antonio ....................................................................... P212Vittoraki, Angeliki G................................................................. P67Vivian, Julian P. ......................................................................... O4Vogel, Benjamin .................................................................... P133Voloshin, Sergey ................................................................... P214Volpin, Monica ....................................................................... O27Voorter, Christina E.M. ............................................ O28,P40,P57Vrana, Milena .......................................................................... P87Vrani, Vasiliki ......................................................................... P146

WWagner, Eva ........................................................................... O37Wagner, Marta ...................................................................... P240Walencik, Alexandre ................................. O60,P104,P119,P135Wang, Hai-Lin........................................................................ P101Wang, Jue ............................................................................... P97Wang, Xiao-nong ................................................................... O38Warnecke, Gregor .................................................................... O3Waterhouse, Miguel ................................................................ O6Watson, Harold ...................................................................... O60Wehmeier, Caroline ............................................................... O41Wenda, Sabine ................................................................ P23,P99Wendel, Jennifer ........................................................... P92,P114Widjaja, Jacqueline M.L. .................................................... O2,O4



Biology (AIBT)

117

Wielińska, Joanna ................................................................. P237Wieten, Lotte .................................................. O25,O26,O28,P40Wiland, Piotr ........................................................................... O64Wilczyńska, Karolina ......................................... P229,P238,P240Wilczyński, Jacek .............................................. P229,P238,P240Wilde, Benjamin ............................................................. O32,O48Willem, Catherine .................................................................. O49Williams, Kevin ...................................................................... P115Williams, Timothy .................................................................... P15Willis, Amanda ...................................................................... P126Wilson, James ........................................................................ O60Wilson, Marie C. ..................................................................... O33Winkler, Cheryl ......................................................................... O5Wiśniewski, Andrzej .................................................... P229,P240Wisse, B.W. .............................................................................. P40Witkowska, Agnieszka ........................................................... O36Witzke, Oliver ................................................................. O32,O48Wojcik, Michal ........................................................................ O36Worah, Kuntal ............................................................... O23,P137Woszczyk, Dariusz ....................................................... P224,P234Wróblewska-Kabba, Sylwia .................................................... P85Wu, Tao Beijing ..................................................................... P153Wysoczańska, Barbara ....................................... O64 ,P218,P237

XXavier, Maria Paula DP. ................................................... O47,P37Xue, Elisabetta ........................................................................ O40

YYahel, Anat............................................................................... P95Yakutik, Igor A. ......................................................................... P77Yang, Jianxin .......................................................................... O43Yang, Soo Young ......................................................... P123,P138Yang, Ya-Chien ........................................................................ P72Yankova, Petiya ........................................................................ P20Yasmill, Ramirez ...................................................................... P92

Yazici, Halil ..................................................................... P39,P185Yeshurun, Moshe ..................................................................... P95Yuanyuan, Jing ........................................................................ P71Yuen, Vivian ............................................................................. P45

ZZakharova, Viktoria .......................................................... P82,P84Zaky, Khaled Abdelmonen ................................................... P233Zanelli, Paola F. ................................................................ P25,P27Zanetti, Adele .......................................................................... P25Zare, Maryam ........................................................................ P167Zarras, Charalampos ............................................................... P29Zavvos, Georgios .................................................................... P67Zdrojowy, Romuald ..................................................... P221,P223Zecca, Marco ......................................................................... P204Zeghal, Khaled ...................................................................... P170Zeier, Martin ........................................................................... O44Zhang, Yi................................................................................ P153Zhongmei, Wang .................................................................... P71Zhunus, Perizat ................................................................... P7,P61Ziyaeyan, Mazyar .................................................................. P167Zizkova, Radka ...................................................................... P109Žižková, Veronika ........................................................ P168,P248Zoccali, Michele .................................................................... P217Zou, Hai ................................................................................. P154Zubala, Marta ......................................................................... O36Zucker, Mark ............................................................................ P42Zunec, Renata .......................... P22,P96,P111,P183,P193,P242Zvonkov, Eugene E. ................................................................. P77



CONFERENCEAND HISTOCOMPATIBILITY32nd

ART AND SCIENCE: THE EVOLVING PICTURE OF IMMUNOGENETICS



Biology (AIBT)

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