art and science: the evolving picture of … - venice may2018... · european immunogenetics...

VENICE LIDO, MAY 9-12, 2018

EUROPEAN IMMUNOGENETICS

CONFERENCEAND HISTOCOMPATIBILITY32nd

ART AND SCIENCE: THE EVOLVING PICTURE OF IMMUNOGENETICS

www.efi2018.org

JOINT CONFERENCE EFI-AIBT

25th Annual Meeting of the Italian Society for Immunogenetics and Transplantation

Biology (AIBT)


CONFERENCEAND HISTOCOMPATIBILITY32nd ART AND SCIENCE:

THE EVOLVING PICTURE OF IMMUNOGENETICS

VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT


Biology (AIBT)

EFI EXECUTIVE COMMITTEEElissaveta Naumova (BG), President

Joannis Mytilineos (DE) President ElectMats Bengtsson (SE), Secretary

Dave Roelen (NL), Deputy SecretaryGwendaline Guidicelli (FR), Treasurer

Katia Gagne (FR), Deputy Treasurer

EFI COUNCILLORSPierre-Antoine Gourraud (FR)

Teresa Kauke (DE)Neema Mayor (UK)Valeria Miotti (IT)Fatma Oguz (TR)Jean Villard (CH)

SCIENTIFIC COMMITTEE AND REVIEWERSCHAIR

Katharina Fleischhauer (DE)

MEMBERSRainer Blasczyk (DE)

Silvia Gregori (IT)Sebastiaan Heidt (NL)James Robinson (UK)

Ludvig Sollid (NO)James Traherne (UK)John Trowsdale (UK)

Luca Vago (IT)Lotte Wieten (NL)

CommitteesLOCAL ORGANIZING COMMITTEE

CONGRESS CHAIRMANValeria Miotti (IT)

CONGRESS CO-CHAIRMENAntonio Amoroso (IT)

Carlo Carcassi (IT)

LOCAL ORGANIZING COMMITTEEMarco Andreani (IT)

Andrea Bontadini (IT)Emanuele Cozzi (IT)Maria E. Fasano (IT)Silvia Gregori (IT)

Luca Mascaretti (IT)Benedetta Mazzi (IT)

Lia Mele (IT)Franco Papola (IT)

Antonina Piazza (IT)Francesca Quintieri (IT)

Nicoletta Sacchi (IT)Manuela Testi (IT)

Luca Vago (IT)

ORGANIZING SECRETARIAT

Planning Congressi srlVia Guelfa 9

40138 Bologna (Italy)Ph. +39 051-300100 Ext. 130

Fax +39 051-309477e-mail: [email protected]

http://www.planning.it






Biology (AIBT)

WELCOME ADDRESSESDear Colleagues and Friends,The 32nd European Immunogenetics and Histocompatibility Conference, joint with the 25th AIBT( Italian Society for Immunogenetics and Transplantation Biology) annual meeting, will be held in Venice, Italy from 9th to 12th of May, 2018.“Art and Science: the evolving picture of Immunogenetics” is the motto of EFI2018 that reflects the dynamism of the Immunogenetics World and its ability to get involved in new addictive biomedical fields, like Leonardo’s masterpiece. I am confident that the meeting will be interesting and exciting, enriching you with the most recent updates in Tissue Typing, Immunogenetics and Transplantation immunology.The conference will take place in the historical buildings of Palazzo del Cinema and Palazzo del Casinò, located in Venice Lido, the quiet, peaceful and green narrow island that stretches between the open sea and the lagoon, just 15 minutes far from St. Mark’s Square.Marvellous Venice, where, everybody knows, there is no traffic jam and you can wander around the labyrinth of narrow cobbled streets and over the countless bridges that criss-cross the canals. You shall not rush and you might lose track of time. Every corner is unique and worth a look for its artistic value or romantic atmosphere.You can get about Venice by water buses, water-taxis or “Gondolas”, which allows you to visit canals and the lagoon.Don’t miss the chance to see “Ponte dei Sospiri” (Bridge of Sighs) where the convicts saw the lagoon before their imprisonment, sighing at their final view of beautiful Venice through the window before being taken down to their cells; Canal Grande (Grand Canal); Rialto Bridge, Churches, Art-galleries, Murano (famous for its glass works) and Burano (famous for the lace shops).It is a great honour and pleasure to invite you to such a unique, romantic, slow, fascinating place named Venice.Looking forward to seeing you all

Valeria MiottiOn behalf of AIBT

and Conference Co-ChairsCarlo Carcassi and Antonio Amoroso






Biology (AIBT)

Wednesday 9 May 2018MARTINELLI ROOM - PALAZZO CASINÒ (2nd FLOOR)

9:00-16:30 Accreditation Commissioners’ Meeting

ROSSI DRAGO ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-16:00 Standards Committee Meeting

CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR)

14:00-15:00 Population Genetics Working Group (close meeting)Katharina Fleischhauer

15:00-16:30 Open Meeting of the Population Genetics Working GroupAlicia Sanchez-Mazas

Thursday 10 May 2018BUY ROOM - PALAZZO CASINÒ (2nd FLOOR)

10:00-12:00 Scientific Committee Meeting

MARTINELLI ROOM - PALAZZO CASINÒ (2nd FLOOR)

12:15-14:30 Executive Committee and Co-ordinators meeting

ASSOCIATED MEETINGSTuesday 8 May 2018

BUY ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-17:30 ESHI diploma examination


8:30-9:30 EBTI Assembly meeting11:30-18:30 IBMDR Meeting

PALAZZO CINEMA FOYER

9:30-17:00 Accreditation Inspectors’ Workshop

Wednesday 9 May 2018AMICI ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-16:00 External Proficiency Testing Committee

BUY ROOM - PALAZZO CASINÒ (2nd FLOOR)

13:30-17:00 Education Committee

MANGANO ROOM - PALAZZO CASINÒ (2nd FLOOR)

8:30-16:30 Executive Committee Meeting






Biology (AIBT)

Wednesday 9 May 2018PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

2° SESSIONEModeratori: Lia Mele, Antonina Piazza

11:45 Epigenetica e nuove tecnologie: cosa cambia nell’associazione HLA e malattie immunomediate Carlo Carcassi

12:15 Il Controllo di qualità Esterno Francesca Quintieri

13:30 Lunch14:45 AIBT nella storia

V. Misefari15:15 Conclusione lavori15:15-16:30 Assemblea dei Soci

AIBT ANNUAL MEETING Accreditato ECM

Wednesday 9 May 2018PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

9:00 Apertura lavori

1° SESSIONEModeratori: Valeria Miotti, Manuela Testi

9:30 Il donatore non familiare, adulto e cord: quali prospettive nell’era del trapianto aploidenticoNicoletta Sacchi

10:00 Anticorpi DSA nel Trapianto di CSE, gestione e desensibilizzazioneAndrea Bontadini

10:30 Metodologia di studio del chimerismo in relazione alle diverse tipologie di trapianto di CSE: ricaduta clinicaMarco Andreani

11:00 Nuovi targets della risposta immune umorale nel trapianto d’organoEmanuele Cozzi

11:30 Coffee break






Biology (AIBT)

Thursday 10 May 2018PALAZZO CINEMA AUDITORIUM

PLENARY SESSION 1Governance of immune-modulation in transplantationChairpersons: Frans Claas, Silvia Gregori

8:30-9:00 Mesenchimal stem cells in transplantationKatarina Le Blanc

9:00-9:30 ExosomeAdrian E. Morelli

9:30-10:00 Innate lymphoid cellsHergen Spits

10:00-10:20 Coffee break & Poster viewing


10:20-11:50 Meet the Expert 1 - ESHI DiplomaMarco Andreani, David Turner

12:00-13:00 Luncheon Session - CareDx13:00-13:30 Lunch13:30-14:30 Luncheon Session - Immucor14:40-16:10 Meet the Expert 2 - EPT External proficiency testing

Falko Markus HeinemannTopics• Extending the Spectrum of EPT in H&I• EPT in H&I: From History to New Developments• Organization of EPT: Schemes, Workshops and Inter-Laboratory Exchanges• Specialist EPT Schemes: HNA, HPA, mHAg and KIR• The Impact of New Technology on EPT: Next Generation Sequencing and

Single Antigen Bead tests - ‘Result based’ or ‘method based’ assessment?

PROGRAMMEWednesday 9 May 2018

PALAZZO CINEMA AUDITORIUM

Opening Ceremony17:30-18:00 Welcome Addresses

Valeria Miotti, Carlo Carcassi, Antonio Amoroso, Elissaveta Naumova, Alessandro Nanni Costa

18:00-18:30 In memory of Jon van Rood Frans Claas

18:30-18:55 Julia Bodmer AwardKatharina Fleischhauer

18:55-19:00 HLA AwardSteven Marsh

19:00-19:30 Ceppellini LectureLorenzo Moretta

Chairperson: Elissaveta Naumova

19:30-20:00 Sounds from Italy - Classic and cinema

20:00-21:30 Welcome Reception






Biology (AIBT)

Thursday 10 May 2018PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

10:20-11:50 Teaching Session 1How NGS technology is changing the way of HLA typingJoannis Mytilineos, Sarah Peacock

12:00-13:00 Luncheon Session - One Lambda13:00-13:30 Lunch14:40-16:10 Teaching Session 214:40-15:05 The clinical relevance of de novo HLA antibodies

in renal transplantationAntonina Piazza

15:05-15:30 The clinical relevance of de novo HLA antibodies in heart transplantationJennifer McCaughan

15:30-15:55 The clinical relevance of de novo HLA antibodies in pancreas and islet transplantationDavid Turner

15:55-16:10 Q&A16:10-16:30 Coffee break & Poster viewing

Thursday 10 May 2018MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

10:20-11:50 Oral Session 1: MHC Evolution - Anthropology - Population Genetics

Chairpersons: Pierre-Antonie Gourraud, Alicia Sanchez-Mazas

13:00-13:30 Lunch14:40-16:10 Oral Session 3:

Immunotherapy - Gene Therapy - Cellular TherapyChairpersons: Rainer Blasczyk, Mats Bengtsson

MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR)

10:20-11:50 Oral Session 2: New Technologies and Bioinformatics

Chairpersons: Emanuele Cozzi, Eric Spierings

12:00-13:00 Luncheon Session - GenDx13:00-13:30 Lunch13:30-14:30 Luncheon Session - Omixon14:40-16:10 Oral Session 4:

Haematopoietic Stem Cell TransplantationChairpersons: Manuela Testi, Jean Villard






Biology (AIBT)

Friday 11 May 2018PALAZZO CINEMA AUDITORIUM

PLENARY SESSION 3HSCT Current clinical perspectivesChairpersons: Luca Vago, Lotte Wieten

8:30-9:00 Haplo settings or Impact of non shared haplotype on haplotransplantLeo Luznik

9:00-9:30 Adoptive Immunotherapies in HSCTChiara Bonini

9:30-10:00 Tregs in HSCTMaria Grazia Roncarolo

MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR)

10:20-11:50 Oral Session 5: Solid Organ Transplantation

Chairpersons: Franco Papola, Dave Roelen

12:00-13:00 Luncheon Session - Bag Healthcare13:00-13:30 Lunch14:40-16:10 Oral Session 7:

Reproduction, Autoimmunity, Infection & CancerChairpersons: Andrea Bontadini, Antonio Martinho

Thursday 10 May 2018PALAZZO CINEMA AUDITORIUM

PLENARY SESSION 2Solid Organ TransplantationChairpersons: Antonio Amoroso, Joannis Mytilineos

16:30-17:00 T regulatory cell based therapy in promoting tolerance solid organ transplantationGiovanna Lombardi

17:00-17:30 Desensitization in SOTChristophe Legendre

17:30-18:00 Novel Biomarkers for allograft rejection in SOTMinnie M. Sarwal

PALAZZO DEL CASINÒ (3rd FLOOR)

18:00-19:30 Poster Session (Wine&Cheese)






Biology (AIBT)

Friday 11 May 2018PALAZZO CINEMA AUDITORIUM

SPECIAL JOINT SESSION WMDA and EFIChairpersons: Lydia Foeken, Elissaveta Naumova, Nicoletta Sacchi

14:40-15:10 Past, Present and future of unrelated Donor registriesLidia Foeken

15:10-15:40 Pharma-economics of CB banking in the haplo eraSergio Querol-Giner

15:40-16:10 How to choose the best unrelated HSC donor?Carolyn Katovich Hurley

16:10-16:30 Coffee break & Poster viewing

PALAZZO CINEMA AUDITORIUM

PLENARY SESSION 4Immunogenetics beyond HLAChairpersons: Marcel Tilanus, John Trowsdale

16:30-17:00 Immunogenetics in AutoimmunityFrancesco Cucca

17:00-17:30 Epigenetic reprogramming in HSCTAngelo Lombardo

17:30-18:00 GWAS in Multiple SclerosisStephen Sawcer

PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)

18:00-19:30 EFI General Assembly

Friday 11 May 2018MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR)

10:20-11:50 Oral Session 6: NK and Miscellaneous

Chairpersons: Benedetta Mazzi, Caner Susal

13:00-13:30 Lunch13:30-14:30 Luncheon Session - Histogenetics


10:20-11:50 Teaching Session 3Tools for a successful HSCT: evaluation of HLA allele frequencies, anti-HLA antibodies, structural and expression models for permissive mismatchesMarcelo A. Fernández-Viña, Katharina Fleischhauer• Allele and haplotype frequencies: How variation affects donor searches• Anti-HLA antibodies: Role of DSA in HLA mismatched transplantation• Coding and non-coding HLA variation: Relationship between T-cell epitopes

and HLA expression levels for permissive mismatches in HSCT12:00-13:00 Luncheon Session - One Lambda13:00-13:30 Lunch


14:40-16:10 Teaching Session 4How to prepare for an inspection: demonstrating how quality standards are MetAndrea Harmer, Luca Mascaretti






Biology (AIBT)

Saturday 12 May 2018PALAZZO CINEMA AUDITORIUM

Closing CeremonyChairpersons: Valeria Miotti, Elissaveta Naumova

12:20-12:50 Closing LectureChairpersons: Carlo Carcassi, Valeria Miotti

Leonardo da Vinci: the prototype of Art & Science manPietro Cesare Marani

12.50-13.00 Jon van Rood Award and Best Abstract AwardsCommittee Chair: Frans Claas

13.00-13.10 Best Poster AwardsCommittee: Marco Andreani, Carlo Carcassi, Luca Mascaretti, Sandra Tafulo, Hien Tran

13.10-13.20 EFI 2019, LisbonAntonio Martinho

13.20-13.30 Closing Remarks

Saturday 12 May 2018PALAZZO CINEMA AUDITORIUM

8:30-10:00 Best Abstract SessionChairpersons: Katharina Fleishhauer, Luca Mascaretti

10:00-10:30 17 IHW reportThe 17th International HLA & Immunogenetics WorkshopMarcelo A. Fernández-ViñaThe 18th International HLA & Immunogenetics Workshop 2021Eric Spierings

10:30-10:50 Coffee break

PLENARY SESSION 5New Frontiers in ImmunogeneticsChairpersons: Elissaveta Naumova, David Turner

10:50-11:20 Single Cell TechnologiesIdo Amit

11:20-11:50 ImmunopeptidomeMarkus Loeffler

11:50-12:20 Neoantigens in Cancer ImmunotherapyCatherine J. Wu

JOINT CONFERENCE EFI-AIBT


Biology (AIBT)




VENICE LIDO, MAY 9-12, 2018

SPEAKERS - CHAIRS






Biology (AIBT)

Mascaretti Luca, Trieste - ItalyMazzi Benedetta, Milano - ItalyMiotti Valeria, Udine - ItalyMorelli Adrian E., Pittsburgh - USAMytilineos Joannis, Ulm - GermanyNanni Costa Alessandro, Roma - ItalyNaumova Elissaveta, Sofia - BulgariaPapola Franco, L’Aquilla - ItalyPeacock Sarah, Cambridge - United KingdomPiazza Antonina, Roma - ItalyQuerol-Giner Sergio, Barcelona - SpainRoelen Dave, Leiden - The NetherlandsRoncarolo Maria Grazia, Stanford - USASacchi Nicoletta, Genoa - ItalySanchez-Mazas Alicia, Genève - SwitzerlandSarwal Minnie M., San Francisco - USASawcer Stephen, Cambridge - United KingdomSpierings Eric, Utrecht - The NetherlandsSpits Hergen, Amsterdam - The NetherlandsSusal Caner, Heidelberg - GermanyTesti Manuela, Roma - ItalyTilanus Marcel, Maastricht - The NetherlandsTrowsdale John, Cambridge - United KingdomTurner David, Edinburgh - United KingdomVago Luca, Milano - ItalyVillard Jean, Geneva - SwitzerlandWieten Lotte, Maastricht - The NetherlandsWu Catherine J., Boston - USA

Speakers - Chairs

Amit Ido, Rehovot - IsraelAmoroso Antonio, Torino - ItalyAndreani Marco, Roma - ItalyBengtsson Mats, Uppsala - SwedenBlasczyk Rainer, Hannover - GermanyBonini Chiara, Milano - ItalyBontadini Andrea, Bologna - ItalyCarcassi Carlo, Cagliari - ItalyClaas Frans, Leiden - The NetherlandsCozzi Emanuele, Padova - ItalyCucca Francesco, Sassari - ItalyFernandez-Vina Marcelo A., Stanford - USAFleischhauer Katharina, Essen - GermanyFoeken Lydia, Leiden - The NetherlandsGourraud Pierre-Antoine, Nantes - FranceGregori Silvia, MIlano - ItalyHarmer Andrea, Sheffield - United KingdomHeinemann Falko Markus, Essen - GermanyHurley Carolyn Katovich, Washington D.C - USALe Blanc Katarina, Stockholm - SwedenLegendre Christophe, Paris - FranceLoeffler Markus, Tübingen - GermanyLombardi Giovanna, London - United KingdomLombardo Angelo, Milano - ItalyLuznik Leo, Baltimore - USAMarani Pietro Cesare, Milano - ItalyMarsh Steven, London - United KingdomMartinho Antonio, Coimba - Portugal

art and science: the evolving picture of … - venice may2018... · european immunogenetics...

Documents