artifacts in cardiac mri andreas sigfridsson, imv/imt/cmiv andreas sigfridsson, imv/imt/cmiv...

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Artifacts in Artifacts in Cardiac MRI Cardiac MRI Andreas Sigfridsson, Andreas Sigfridsson, IMV/IMT/CMIV IMV/IMT/CMIV <[email protected]> <[email protected]> 2007-04-27 2007-04-27

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Page 1: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

Artifacts in Cardiac MRIArtifacts in Cardiac MRI

Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV <[email protected]><[email protected]>

2007-04-272007-04-27

Page 2: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Dynamic imagingDynamic imaging

Images are acquired line-by-line in Images are acquired line-by-line in k-k-spacespace Motion during acquisition causes Motion during acquisition causes artifactsartifacts, not , not

blurringblurring Special care must be takenSpecial care must be taken

TriggeringTriggering

Acquisition orderingAcquisition ordering

Page 3: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

ExampleExample

Simulation exampleSimulation example 256x256, TR=20 ms, total scan time ~5 s256x256, TR=20 ms, total scan time ~5 s

Image domain k-space

Page 4: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Signal saturationSignal saturation

Signal recovery - relaxationSignal recovery - relaxation

11 T

t

z eM

0t

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Page 5: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Signal saturationSignal saturation

Progress to steady-stateProgress to steady-state

901 TTR

0 0.2 0.4 0.6 0.8 1 1.2-0.5

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Page 6: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Varying signal during inflowVarying signal during inflow

The MR signal is increased during inflowThe MR signal is increased during inflow

Signal increase related to flow velocitySignal increase related to flow velocity More magnetization because of T1 More magnetization because of T1

decay/recoverydecay/recovery

Static spins, saturated signal

Flowing spins, fresh signal

Page 7: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Varying signal intensityVarying signal intensity

Simulated six sinusoidal heart beatsSimulated six sinusoidal heart beats

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Intensity Image (animation)

Page 8: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Varying signal intensity, resultsVarying signal intensity, results

Reconstructed imageReconstructed image

High contrastNormal contrast

Page 9: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Varying signal intensity, k-spaceVarying signal intensity, k-space

Image artifacts because of k-space Image artifacts because of k-space samplingsampling Different lines are acquired with different Different lines are acquired with different

signal intensitysignal intensity

Page 10: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Varying signal intensity, analysisVarying signal intensity, analysis

Analyze signalAnalyze signal

dynamicstatic ImagetIntensityImagetImage *)()(

)(*)()()( ydynamicyystaticy kKkIntensitykKkK

dynamicstatictedreconstruc ImagetIntensityImageImage ))(FT(

)*FT()FT()FT( dynamicstatic KIntensityKK

)FT()FT()FT()FT( dynamicstatic KIntensityKK

Page 11: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Slow sine variationSlow sine variation

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Intensity FT(Intensity)

Page 12: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Varying signal intensity, resultsVarying signal intensity, results

Reconstructed imageReconstructed image

High contrastNormal contrast

Page 13: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Fast sine variationFast sine variation

Intensity FT(Intensity)

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Page 14: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Fast sine variationFast sine variation

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Intensity FT(Intensity)

Page 15: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

““Physiological” variationPhysiological” variation

Aortic flow (handcrafted, not actual data)Aortic flow (handcrafted, not actual data)

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Intensity (one beat)

Intensity (whole scan)

Page 16: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

““Physiological” variationPhysiological” variation

Intensity variation (animation)

Page 17: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

““Physiological” variationPhysiological” variation

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Intensity

FT(Intensity)

Page 18: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

““Physiological” variationPhysiological” variation

Reconstructed imagesReconstructed images

High contrastNormal contrast

Page 19: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

RemediesRemedies

TriggeringTriggering Wait for ECG R-tagWait for ECG R-tag Wait additional trigger delay timeWait additional trigger delay time Acquire one (or several) k-space linesAcquire one (or several) k-space lines

Acquisition reorderingAcquisition reordering Measure current cardiac (or respiratory phase)Measure current cardiac (or respiratory phase) Choose k-space line to acquireChoose k-space line to acquire Creates a slow varying intensity curve along k-spaceCreates a slow varying intensity curve along k-space

Page 20: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Triggering - random phaseTriggering - random phase

If triggering is not accurate, random If triggering is not accurate, random variations will still be leftvariations will still be left

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Intensity FT(Intensity)

Page 21: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Random phase, reconstructedRandom phase, reconstructed

Normal contrast High contrast

Page 22: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Acquisition reorderingAcquisition reordering

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FT(Intensity)

Page 23: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Acquisition reorderingAcquisition reordering

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OrderedRandom

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Page 24: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Acquisition reorderingAcquisition reordering

Reconstructed imagesReconstructed images

High contrastNormal contrast

Page 25: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Actual examplesActual examples

ECG triggering failedECG triggering failed

Page 26: Artifacts in Cardiac MRI Andreas Sigfridsson, IMV/IMT/CMIV Andreas Sigfridsson, IMV/IMT/CMIV 2007-04-27

[email protected]

Dynamic imagingDynamic imaging

Images are acquired line-by-line in Images are acquired line-by-line in k-k-spacespace Motion during acquisition causes Motion during acquisition causes artifactsartifacts, not , not

blurringblurring Special care must be takenSpecial care must be taken

TriggeringTriggering

Acquisition orderingAcquisition ordering Artifacts might be predictable through use of Artifacts might be predictable through use of

Fourier transformFourier transform