automation solutions to enable phynexus applications · • reaches all deck space • landscape...
TRANSCRIPT
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HAMILTON Life Science Robotics
Automation Solutions to Enable PhyNexus Applications
Bronson Duck August 27th, 2014
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About Hamilton • Global Company • Provides world-class analytical components, medical instrumentation, sensors, laboratory robotics and automated liquid handling equipment. • High quality products • Superior service and customer satisfaction
Clark Hamilton, Founder of Hamilton Company, started the company in his garage in 1950 and today, Hamilton is a proud employer of over 1200
employees worldwide.
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Tools that Enable PhyNexus Applications
Modules
Configurations
Accessories
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Hamilton Robotics – Platform Products
MICROLAB VANTAGE
MICROLAB STAR
MICROLAB NIMBUS
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Microlab STAR – The Success Story
Microlab STAR
1,000s of Installations Around the World
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Key Innovations - CO-RE Technology
CO-RE = Compression-induced O-Ring Expansion
• Disposable tips and steel washable needles on the same head, during the same run
• Highest positional accuracy along all axes
• Stress-free Tip Pick-Up • Contamination-free tip drop-off • Universal Tool
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Pipetting Channels
• Monitored Air Displacement Pipetting principle (MAD)
No system liquid, no tubing, no pumps
• Channel Capacity 1000µl • Pipetting Heads with Independent
Volume from 0.5 – 1000µl Pipetting height Asymmetric, variable span in Y direction
• Totally accessible deck Each channel accesses each well on all
pipetting locations
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96 Pipetting Channels with One volume: 1µl - 1000µl
CO-RE Technology Offers
1 Tip row pick-up 1 Tip column pick-up
High Throughput
CO-RE 96-probe Head
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Hamilton STAR Solution
STAR ML 8/96 Key Hardware
1mL CORE 96 Head Tip Column Drying Station Chilled Positions for Sample Stability
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CORE 96 Head
STAR ML 8/96 Key Hardware
1mL CORE 96 Head Tip Column Drying Station Clear 1mL Tips supplied to PhyNexus
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PhyNexus Drying Station
STAR ML 8/96 Key Hardware
1mL CORE 96 Head Tip Column Drying Station Clear 1mL Tips supplied to PhyNexus
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Chilled Carrier
Chilled Positions for Sample Stability
Temperature Control down to 4°C
5 – 45 Temperature Controlled Positions
Allows for additional throughput and longer walk-away times
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Microlab STARline – 3 Sizes
STARlet (25 SBS)
STAR (45 SBS)
STARplus (55 SBS)
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Ability to Automate Additional Applications
Vacuum based purifications Magnetic bead based purifications PCR/sequencing set-ups Cloning Protein crystallization In-gel digestion MALDI target spotting Cell culture Cell based assays Antibody production RNAi, reporter gene screening Solid phase and liquid/liquid extraction PAMPA and other ADME(T) Combichem
Check: www.hamiltonrobotics.com
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iSWAP Robotic Plate Handler
• Access Internal and External Positions
• Process Control Through Force Sensor
• Mimics Human Arm • Default Positions for
Labware • Fully Compatible with
1 - 16 Single Channels • Landscape and Portrait
Plate Gripping
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CO-RE Grip Plate Handler
• Small Budget Plate Handler • Tool Picked-up by Two
Channels • Default Positions for
Labware • Reaches All Deck Space • Landscape and Portrait
Plate Gripping • Facilitates Stacking
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STAR DeCapper
• Consists of Twister Channels and DeCapper Modules • Supports manipulation of a variety of tube diameters & heights • Integrated barcode reader on each Twister Channel • 1500 rpm mixing speed
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STAR Configuration - Loading
Autoload/Barcode Reading
Manual Load
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Key Benefits to Automating PhyNexus Applications on a Hamilton Robotics Platform
• CORE 96 Head • 1mL Capacity allows for a wide range of PhyNexus applications • Increased throughput
• Air Displacement Pipetting Technology • Allows for more mixing cycles without disrupting or resetting air
gaps in fluid filled lines
• Functionality & Flexibility • Ability not only to automate protein and plasmid DNA
purifications, but additional liquid handling tasks • Many configuration and accessory options allow for automation
of practically any liquid handling task
• Worldwide Service & Support Organization
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Hamilton Life Science Robotics