awv report template · web view2020. 4. 29. · if the counting of neonates risks impact to...

AWV Report Template

ANIMAL USE RETURN

SUBMISSIONS GUIDELINE

2

Animal Use Return Submission Guideline 2019

ContentsSUBMISSION OF ANNUAL ANIMAL USE RETURN DOCUMENTS21.The annual return consists of three parts22.Submitting the return3QUERIES INCLUDING OBTAINING COPIES OF FORMS3ANIMALS TO BE REPORTED IN PART A OF THE RETURN41.Animal use42.Animal developmental stage43.Specified animals44.Degree of participation in protocols45.Animals reported in a previous year46.Animal use outside of Victoria57.Collaborative projects58.Animal breeding colonies5DATA ENTRY FOR ANIMAL USE RETURN PART A6Grouping of animals for data entry6Category descriptions and examples6A.Year6B.Licence number6C. Reason for use6D. AEC identification code7E. AEC Approval Date7F. Type of animal in group7G. Source of group7H. Project purpose or animal breeding colony group7I.Project benefit or animal breeding colony group8J. Particular procedure applied to the group8K. Impact of activities or GM status of animal breeding colony group8L. Number of animals in group in 201911M. Number of deaths in the group in 201911APPENDIX 1: CATEGORIES FOR COLUMNS F, G, H, I, J, K,12Column F. Type of animal in group (* Specified animals)12Column G. Source of group12Column H. Project purpose or Animal Breeding Colony group13Column I. Project benefit or Animal Breeding Colony group13Column J. Particular procedure applied to the group (reporting is optional)14Column K. Impact of activities or GM status of Animal Breeding Colony group14APPENDIX 2: EXAMPLES OF A COMPLETED PART A,15Procedure groups15Animal use in AEC approved breeding projects with offspring assigned to AEC approved research projects involving scientific procedures17APPENDIX 3: EXAMPLES OF WHAT IS CONSIDERED ‘PRIMARY PURPOSE’ BREEDING FOR USE IN SCIENTIFIC PROCEDURES AND REPORTING REQUIREMENTS19

SUBMISSION OF ANNUAL ANIMAL USE RETURN DOCUMENTS

The annual return must be submitted before 31 March 2020 for all scientific procedures premises (SPPL), scientific procedures fieldwork (SPFL), and specified animals breeding (SABL) licences held for any period during 2019, regardless of whether animals were used or not.

Penalties apply for failing to submit an annual return by the due date or providing false or misleading information. Penalty infringement notices and fines may be issued.

The licence holder is responsible for the accuracy of information, Animal Welfare Victoria (AWV) does not undertake an accuracy check prior to accepting the submission as final. Information is provided for guidance in completing the return; AWV does not intend this to be a substitute for an understanding of all applicable legislative requirements.

1. The annual return consists of three parts

The licence holder is responsible for submitting a complete and accurate return. Submission of Part B is compulsory for all licence holders. Part A must be submitted if there has been animal use under the licence, and Part C only if applicable.

Part A requires details of animals assigned to or used in projects including animals within breeding colonies.

· Part A (an excel spreadsheet) is to be completed only if animals were used for activities under the licence in 2019, including animals kept in a breeding colony.

· Where there are multiple AECs nominated under one licence, a separate Part A may be completed for each AEC associated with a licence.

Part B incorporates a declaration by the licence holder, summarises animal use under the licence, and details the licence holder’s commitment to the principles of replacement, reduction, refinement.

· One form is to be completed for each licence and must be completed even if animals were not used under the licence in 2019.

Part C relates to scientific procedures where death is the end point.

· Death as an end point is where the death is a deliberate measure in the procedure and where there will be no intervention to kill the animal humanely before death occurs in the course of the procedure or procedures.

· These procedures must not be conducted unless approved by the Minister for Agriculture and are undertaken in accordance with any conditions determined by the Minister.

· Completion of part C (in addition to part A) is required where any procedures where death was the end point were conducted under the licence in 2019.

· A separate part C is required for each project involving scientific procedures where death was the end point.

2. Submitting the return

All relevant parts are to be submitted at the same time and must reference the applicable five-digit licence number.

The Part A table must be submitted by:

· Naming the spreadsheet using licence name, licence number and AEC name (where multiple AECs are nominated under a licence and reported separately)

· Ensuring the name and/or number of the licence is in the email subject line

· E-mailing the spreadsheet as an attachment to: [email protected]

The signed Part B form and Part C form (where relevant) may be submitted electronically from:

· the email address of the licence nominee, or

· from another email address ONLY if the licence nominee is copied-in.

Originals of signed Part B form and Part C form (where relevant) are only required (by post or direct delivery) when it is not possible to submit these electronically in accordance with the above instruction.

QUERIES INCLUDING OBTAINING COPIES OF FORMS

These guidelines and Part A, B, and C forms may be obtained from [email protected] or from the forms page at www.agriculture.vic.gov.au/ART

Queries regarding the animal use return should be directed to:

Licensing and Audit

Animal Welfare Victoria

DJPR

475 Mickleham Rd

ATTWOOD VIC 3049

Ph: 03 8377 4586

[email protected]

ANIMALS TO BE REPORTED IN PART A OF THE RETURN1. Animal use

All animals used under a licence issued under the Prevention of Cruelty to Animals Act 1986 (POCTA Act) during 2019 must be reported to AWV yearly using AWV’s annual return Part A form.

Do not report AEC approved projects that did not have any animals assigned or used during 2019.

Do not report any animal use by the organisation that did not involve scientific procedures or breeding primarily for use in scientific procedures (see Appendix 3). Only activities covered by Part 3 of the Prevention of Cruelty to Animals Act 1986 (POCTA Act) should be reported.

· Information on exempt activities may be found at: http://agriculture.vic.gov.au/agriculture/animal-health-and-welfare/animals-used-in-research-and-teaching/licensing/activities-requiring-a-licence

Only animals alive at the time of issue to a project are to be reported. Use of carcasses or tissue from animals acquired after death (for example humanely killed in another reported approved project or for a reason unrelated to activities conducted under the licence) does not require reporting.

If the counting of neonates risks impact to animal welfare, it is acceptable to delay active monitoring until the earliest appropriate time point. For example, for mice, week one may be appropriate. This arrangement must be justified to and approved by the AEC. All animals identified at the approved timepoint, living and dead, must be counted and recorded under the relevant AEC approval and reported within the annual animal use return.

2. Animal developmental stage

For the purposes of Part 3 of the POCTA Act the following stages of development apply:

· reptiles, birds, and mammals are considered animals after the half-way point of gestation or incubation;

· fishes and amphibians are considered animals when they are capable of self-feeding (for zebrafish this is 7 days); and

· decapod crustaceans and cephalopods are considered animals when adult.

3. Specified animals

Specified animals are guinea pig; and rat, mouse or rabbit other than a rat, mouse or rabbit bred in the wild; and non-human primates.

4. Degree of participation in protocols

All animals assigned, issued or used under a project for any period in 2019 must be reported in that project.

This may result in an animal being reported more than once if it is assigned to more than one project. This ‘reuse’ of animals in scientific procedures requires specific AEC approval. There are two exceptions:

· Where animals were issued and identified as not suitable, did not undergo any scientific procedures and were immediately returned to the source it is not necessary to report these animals under the project to which they were assigned.

· For animals in breeding colonies there are specific requirements to prevent ‘double reporting’. See sections 8 and D and Appendix 2.

5. Animals reported in a previous year

An animal must be reported each year in which it is used within a project, regardless of any reporting in previous years.

6. Animal use outside of Victoria

Only animals used in Victoria or Victorian waters are to be reported.

7. Collaborative projects

To prevent duplication of reporting, animal use must be reported only by the licence under which the AEC approved the animal use.

8. Animal breeding colonies

Specified animals and other species kept in breeding colonies for the primary purpose of use in scientific procedures (see appendix 3) under the licence must be reported under the relevant AEC breeding approval, excluding progeny distributed for use in another project. These animals are reported under the project and licence that uses them (see Appendix 2 for examples).

The number of animals to be reported for a breeding colony is the sum of:

· animals present at the start of the year; and

· animals acquired; and

· animals born, including neonates humanely killed or found dead

minus live animals assigned to AEC-approved projects.

Note that animals issued and returned unused must be reported under the relevant breeding colony.

DATA ENTRY FOR ANIMAL USE RETURN PART A

An Excel worksheet is provided to complete Part A of the Return. Where pre-set options are to be used, there are drop-down boxes which must be used.

Below the title of column cells is a link to the relevant ‘help section’ in the ‘help text’ worksheet. To return to the data entry worksheet, click on the ‘Data entry’ tag on the left-hand side of the bottom scroll bar.

Pasting of entries may cause internally inconsistent or non-standard entries to occur. Spreadsheets with these incorrect entries will be returned for correction.

Grouping of animals for data entry

Animals used in scientific procedures are to be reported in groups. A separate line is to be used to describe each group within an approved project.

Breeding colony animals are to be reported in groups by:

· Animal type;

· Animal source; and

· Whether the animals are non-GM or are involved in breeding established GM lines.

All other animals used are to be reported in groups by:

· Animal type;

· Animal source;

· Particular procedure (optional); and

· Impact of different types of procedure on animals within a project (e.g. test group, control group, animals assigned but not used in a procedure, etc).

Category descriptions and examples

Following is a description of the entries for each column of the data entry worksheet. The total list of options in the drop-down boxes are in Appendix 1, and examples of completed forms are in Appendix 2.

A. Year

Enter the reporting period year in four-figure format (2019) by using the drop-down box.

B. Licence number

Enter the five-digit licence number with the four-letter prefix omitted. For example, for licence SPPL20134 only 20134 should be entered.

Note: many licence numbers changed in 2017, do not reference a previous number.

C. Reason for use

There are three drop-down boxes relating to the overall purpose of use:

*AEC approved project - Specified animal breeding colony applies to specified animals held or produced for stock maintenance and/or routine breeding. Where the return relates to a specified animal breeding licence, ‘specified animal breeding colony’ must be selected for all groups.

AEC approved project – Non-specified animal breeding colony applies to non-specified animals held or produced primarily for use in scientific procedures (see Appendix 3 for examples).

AEC approved project is to be selected for all other animal use.

Where the purpose of use is generation of a new line of GM animals, the ‘AEC approved project’ option must be selected.

D. AEC identification code

This is the AEC approval reference applied by the AEC to the approval of animal use.

For breeding colonies where one project authorising AEC approval of animal use expired and another commenced during 2019, specify both AEC project identification codes within the one row. If there is no AEC approval reference for a breeding colony write N/C in column D and leave the approval date (column E) blank. See also Appendix 2.

E. AEC Approval Date

The date when the AEC approved, must be written in the format: dd/mm/yyyy e.g. 12 November 2019 is to be entered as 12/11/2019.

This is required for all groups, including specified and non-specified animal breeding colonies. Where two projects authorised activities in breeding colonies (due to expiry and approval of a new project) provide the date of approval of the most recent project.

F. Type of animal in group

See Appendix 1 for the list of options provided within drop-down boxes. Note that “specified animals” are asterisked.

G. Source of group

See Appendix 1 for the list of options provided within drop-down boxes.

For all specified animals, a source marked with an asterisk must be chosen.

For non-specified animals, a non-asterisked source must be chosen.

H. Project purpose or animal breeding colony group


Because this option applies to the project as a whole, it must be identical for all groups that are part of the same project.

For animal breeding colonies choose either specified or non-specified animal breeding colony.

For all other AEC approved projects, select the most appropriate option that describes the primary purpose of the project as a whole, or the purpose of the project for which new-line GM animals are being produced.

“The understanding of human or animal biology”: projects that aim to increase the basic understanding of the structure, function and behaviour of animals, including humans, and processes involved in physiology, biochemistry and pathology.

“The maintenance and improvement of human or animal health and welfare”: projects that aim to produce improvements in the health and welfare of animals, including humans.

Examples

· Use of a sheep flock to donate blood to produce microbiological media

· Production of commercial anti-serum, antivenom

“The improvement of animal management or production”: projects that aim to produce improvements in domestic or captive animal management or production.

“The achievement of education objectives”: the purpose of the project is not to acquire new knowledge, rather to pass on established knowledge or training to others. This includes interactive classes in methods of animal husbandry, management, examination and treatment.

Examples

· Animals used by veterinary schools to teach examination procedures such as pregnancy diagnosis

· Animals used to teach animal care to TAFE students

“Environmental objectives”: projects that aim to increase the understanding of the animals’ environment or its role in it, or investigate management techniques for wild or feral populations. These include studies to determine population levels and diversity and may involve techniques such as radio tracking.

I. Project benefit or animal breeding colony group


Select the most appropriate option that describes the primary purpose of the project as a whole.

J. Particular procedure applied to the group

This column describes specific procedures that may have been undertaken on the group.

The POCTA Regulations 2019 came into effect on 14 December 2019. Reporting of the particular procedure is no longer required and completion of this section is optional.

DO NOT DELETE THIS COLUMN – IT MAY BE LEFT BLANK

If entering data and one of the listed procedures has been conducted, select that option. If none of these procedures have been used, select the ‘other procedure’ option.

K. Impact of activities or GM status of animal breeding colony group


For animal breeding colony groups select one of the following options.

· “Specified animal breeding colony group: non-GM breeding only”: routinely bred specified animals with no genetic modification

· “Specified animal breeding colony group: established GM line”: specified animals that have undergone genetic modification (or are from lines of animals resulting from genetic modification)’

· “Non-specified animal breeding colony group”: applies to non-specified animals held or produced primarily for use in scientific procedures

· “Non-specified Animal Breeding Colony group established GM line” animals that have undergone genetic modification (or are from lines of animals resulting from genetic modification)

For all other AEC-approved projects, this column describes the impact of activities on the welfare of the animals in each group. Select the option reflecting the activity with the highest impact on the group in the reporting year. For animals that die or are euthanased prior to reaching the conclusion of the project, select the option representing the highest impact activity that the animal actually experienced.

“Observation involving minor interference”: studies which involve scientific procedures with minimal impact on the normal activities of animals.

Examples:

· Laboratory animals in cages

· Feeding trial, such as digestible energy determination of feed in a balanced diet

· Behavioural or growth study with minor environmental manipulation

· Teaching of normal, non-invasive husbandry such as handling, grooming, etc

· Production of products, such as hormones or drugs, in milk or eggs from genetically modified animals that are subject to normal husbandry procedures only

· Any of the above where the animal is euthanased at the culmination of its use.

“Animal unconscious without recovery”: the animals are rendered unconscious under controlled circumstances (i.e. not in a field situation) with as little pain or distress as possible. Capture methods are not required. Any pain is minor and brief and does not require analgesia. Procedures are carried out on the unconscious animal that is then killed without regaining consciousness.

Examples

· Animals (including fish) in a laboratory killed humanely for dissection, biochemical analysis, etc

· Teaching surgical techniques on live, anaesthetised patients that are not allowed to recover following the procedure

“Minor conscious intervention”: the animals are subjected to minor procedures that would normally not require anaesthesia or analgesia. Any pain is minor and analgesia usually unnecessary, although some distress may occur as a result of trapping or handling.

Examples

· Capture and release (with or without tagging- note, see page 4 exempt activities) of animals (including fish) in the wild. Excludes electrofishing, refer to Minor Physiological Challenge.

· Trapping and humane euthanasia for collection of specimens

· Ear notching for DNA sampling of a new line of GM animals

· Injections, blood sampling in conscious animals

· Minor dietary or environmental deprivation or manipulation, such as feeding nutrient-deficient diets for short periods

· Stomach tubing, shearing

“Minor operative procedure with recovery”: the animals are rendered unconscious, with as little pain or distress as possible. A minor procedure such as cannulation or skin biopsy is carried out and the animals are allowed to recover (although the animal may later be humanely killed). Depending on the procedure, pain may be minor or moderate and post-operative analgesia may be appropriate.

Examples:

· Biopsies or blood sampling under anaesthesia or sedation

· Cannulations under anaesthesia or sedation

· Sedation/anaesthesia for relocation, examination or injections/blood sampling

· Field capture using chemical restraint methods

“Minor physiological challenge”: the animals remain conscious for some or all of the procedure. There is interference with the animals’ physiological or psychological processes. The challenge may cause only a small degree of pain/distress or any pain/distress is quickly and effectively alleviated.

Examples:

· Electrofishing

· Minor infection, minor or moderate phenotypic modification, early oncogenesis

· Arthritis studies with pain alleviation.

· Prolonged deficient diets, induction of metabolic disease.

· Polyclonal antibody production

· Antiserum production

“Surgery with recovery”: generally, the animals are rendered unconscious, with as little pain or distress as possible. A major procedure is carried out and the animals recover (although the animal may later be humanely killed). Post-operative pain is usually at a level requiring analgesia.

Examples

· Orthopaedic surgery

· Abdominal or thoracic surgery

· Transplant surgery

· Mulesing, surgical castration

· Surgery under anaesthesia for implantation of telemetry devices

“Moderate to major physiological challenge”: the animals remain conscious for some or all of the procedure. There is interference with the animals’ physiological or psychological processes. The challenge causes a moderate to severe impact that is not promptly alleviated.

Examples

· Major infection, major phenotypic modification, oncogenesis without pain alleviation

· Arthritis studies with no pain alleviation, uncontrolled metabolic disease

· Isolation or environmental deprivation for extended periods

“Death as an end point”: See definition on page 2 (Part C form) of this guideline.

Do not use this classification to report animals that are humanely killed or die prior to the planned endpoint of the project.

Where an animal is subjected to scientific procedures where death is the end point, this option must always be chosen even when other procedures have been undertaken prior to death.

L. Number of animals in group in 2019

Include only animals that are used under the licence.

Enter the total number of animals in the group during 2019. Where a precise measure of the numbers is impractical, such as for very large groups of animals (e.g. fish schools) or for non-captive animals, an estimate is satisfactory.

For animal breeding colony groups, this is the sum of:

· animals at the start of the year;

· animals acquired; and

· animals born,

minus live animals assigned to other projects.

M. Number of deaths in the group in 2019

Enter the number of animals in the group that died during the reporting period. This includes animals that are humanely killed, death as an end point, or death by other causes.

To calculate the number of deaths in a breeding colony, subtract the number of animals alive at the end of the year from the total number of animals reported for the colony.

Where the options “animal unconscious without recovery” or “death as an end-point” are chosen in the impact column (column K), that group must have 100% deaths (ie the same numbers in the number used (column L) and number of deaths columns (column M). If animals are alive at the end of the calendar year for the same project these must be described as a separate group in a new line.

The number of animals dead with a group may never exceed that used or held. Therefore, the number in column M may never be more than that in column L.

APPENDIX 1: CATEGORIES FOR COLUMNS F, G, H, I, J, K,

Shaded sections indicate choices exclusive to and compulsory for specified animal breeding colony animals

Column F. Type of animal in group (* Specified animals)

Specified Animals

Birds

· Native Rats, Mice

· *Guinea pigs (lab)

· Exotic captive

· Possums, Gliders

· *Mice (lab)

· Exotic wild

· Wombats

· *Rabbits (lab)

· Native captive

· Monotremes

· *Rats (lab)

· Native wild

· Seals and sealions

· *Baboons

· Poultry

· Whales and dolphins

· *Macaques

· Other birds

· Other native mammals

· *Marmosets

Aquatic

Exotic feral mammals

· *Primates other

· Cephalopods

· Camels (wild)

Other Laboratory (non-specified)

· Crustaceans

· Cats (wild)

· Ferrets (lab)

· Fish

· Cattle (wild)

· Laboratory mammal

(non-specified)

Amphibia

· Goats (wild)

Domestic mammal

· Amphibians

· Hares (wild)

· Cattle (domestic)

Reptiles

· Horses (wild)

· Deer (domestic)

· Lizards

· Mice (wild)

· Goats (domestic)

· Snakes

· Pigs (wild)

· Horses (domestic)

· Turtles, tortoises

· Rabbits (wild)

· Pigs (domestic)

· Other reptile

· Rats (wild)

· Sheep (domestic)

Native mammal

· Wild dogs and foxes

· Cats (non-wild)

· Dasyurids

· Other exotic feral mammal

· Dogs (non-wild)

· Koalas

Zoo

· Other domestic

· Macropods

· Exotic zoo mammal

Column G. Source of group

For specified animals (guinea pig; non-wild bred

All other animals cont

mouse, rat & rabbit; primate)

· Commercial supplier

· *Own derivation, or

· Private donation

· *Victoria –Specified Animals Breeding Licence, or

· Municipal pound

· *Interstate institution authorised to distribute

· Privately owned animals used on a farm

specified animals

· Animals in their natural habitat

· *Imported from overseas

· Removed from Australian natural habitat

· *Other

for the project

All other animals

· Australian captive colony/zoo

· Own derivation

· Other source

Column H. Project purpose or Animal Breeding Colony group

Fundamental purpose of project

Project purpose continued

· The understanding of human or animal biology

· The achievement of educational objectives

· Maintenance and improvement of human or

· Environmental objectives

animal health and welfare

Specified Animal Breeding Colony

· Improvement of animal management or

(Guinea pig; non-wild bred mouse, rat, rabbit; primate)

production

· *Specified Animal Breeding Colony group

· Non-specified Animal Breeding Colony group

Column I. Project benefit or Animal Breeding Colony group

Benefit provided by project

Project benefit continued

· Fundamental biology/physiology

· Development of techniques- remedial, surgical,

· Diseases-human

diagnostic

· Diseases-animal

· Education (demonstration)

· Diseases- zoonotic

· Training (student use of animals)

· Environmental monitoring/ecology

· Regulatory product testing (e.g. vaccines, chemical,

· Domestic animal management/production

drug evaluation)

· Wildlife management/conservation

Specified Animal Breeding Colony animals only

· Vertebrate pest management

(Guinea pig; non-wild mouse, rat, rabbit; primate)

· Production of biological products


· Xenotransplantation (transplantation of living organs, tissues or cells from one species to another)


Column J. Particular procedure applied to the group (reporting is optional)

Key particular procedures; if not relevant select ‘Other’

Procedure continued

· Attachment or insertion of devices for long term direct

· In vivo production of monoclonal antibody

or telemetric monitoring

· In vivo production of polyclonal antibody

· Aversive stimuli for behavioural training, or for

· Ionising radiation exposure

inducing a state of stress integral to the experiment

· Neuromuscular blocking agents or electro-

· Burning or scalding

immobilisation

· Induction of other disease model (e.g. diabetes, cardiac

· Ocular irritancy testing

disease)

· Skin irritancy testing involving a chemical, or

· Gene manipulative technology

cosmetic, household, or industrial preparation

· Immunomodulatory methods

· Toxicity testing

· Induction of infection

· Other procedure

· Induction of neoplasia


· Interference with the central nervous system or sensory

(Guinea pig; non-wild mouse, rat, rabbit; primate)

capacity or brain centres controlling that capacity



Column K. Impact of activities or GM status of Animal Breeding Colony group

Impact of the procedure on the group

Impact of procedure continued

· Observational study involving minor interference

· Death as an end point - MUST COMPLETE PART

· Animal unconscious without recovery

C FORM

· Minor conscious intervention, no anaesthesia


· Minor operative procedures with recovery

(Guineapig; non-wild mouse, rat, rabbit; primate)

· Minor physiological challenge

· *Specified Animal Breeding Colony group (non-GM)

· Surgery with recovery

· *Specified Animal Breeding Colony group established

· Moderate to major physiological challenge

GM line

· Non-specified Animal Breeding Colony group (non-GM)

· Non-specified Animal Breeding Colony group established GM line

Page 2 of 2

Animal Return Submission Guideline 2

APPENDIX 2 - EXAMPLES OF A COMPLETED PART A,

Animal use in AEC approved projects (other than breeding projects)

The following table illustrates how the animal use is to be reported. The inclusion of ‘group numbers’ are illustrative only and should not be included in the submitted worksheet. In 2019, under licence SPPL20999, mice and rats (specified animals) and fish were used in Projects 00061 and 00046.

Procedure groups

Project 00061 was assigned rats and mice, with similar procedures on all the animals. As such, the project was broken down into 2 groups, one for the mice and one for the rats. However, 10 rats were assigned to but did not undergo procedures in 2019. A third line was used to describe these animals with zero in column M as these rats were carried-over for future procedures under the project (Group 3).

Project 00046 was assigned laboratory mice and fish, forming 2 initial groups, 19 fish were humanely killed and 5 recovered from minor operative procedures. To describe this variability the fish group was further split into 2, and ultimately the project was described in 3 groups (lines). Zero was entered under the ‘All deaths’ Column M for group 2, to indicate that no animals died or were killed in this group.

Animal Submission Guideline 2

A

Year

B

Licence no.

C

Reason for use

D

AEC identification code

E

AEC approval date

F

Type of animal

G

Source

H

Purpose of animal use

I

Benefit focus of animal use

J

Particular procedure

K

Impact on animals

L

Total used

M

All deaths

Group 1

2019

20999

AEC-approved project

00061

1/4/2017

Mice

Own derivation

Maintenance human health or animal health and welfare

Diseases human

Other procedure

Animal unconscious without recovery

20

20

Group 2

2019

20999


00061

1/4/2017

Rats

Own derivation


Diseases human

Other procedure


75

75

Group 3

2019

20999


00061

1/4/2017

Rats

Own derivation


Diseases human

Other procedure

Observational study involving minor interference

10

0

Group 1

2019

20999


00046

27/6/2018

Fish

Commercial supplier

Understanding of human or animal biology

Fundamental biology/physiology

Other procedure


19

19

Group 2

2019

20999


00046

27/6/2018

Fish

Commercial supplier



Other procedure

Minor Physiological challenge

5

0

Group 3

2019

20999


00046

27/6/2018

Mice

Own derivation



Other procedure


5

5

Animal use in AEC approved breeding projects with offspring assigned to AEC approved research projects involving scientific procedures

This example demonstrates animal use and reporting of two breeding colonies; mice (specified animal) and cats (non-specified animal) and subsequent allocation of animals for use in AEC approved projects (non-breeding).

(Note completion of column J is optional – in this example it has been left blank)

APPENDIX 3 EXAMPLES OF WHAT IS CONSIDERED ‘PRIMARY PURPOSE’ BREEDING FOR USE IN SCIENTIFIC PROCEDURES AND REPORTING REQUIREMENTS

The following examples are provided for guidance in reporting to AWV in the annual return.

Example

Reporting to AWV in the annual return

A herd of breeding cattle is co-located on a farm that is also used to keep animals allocated to research projects involving scientific procedures. There are no activities undertaken on the breeding herd specifically related to the use of offspring in scientific procedures. Some offspring are assigned to projects at weaning while others are maintained within the herd for meat production.

Animals assigned to research projects

A flock of breeding sheep is co-located on a farm that is also used to keep animals allocated to research projects involving scientific procedures. Reproductive technology is used at various time points to provide pregnant sheep at a known point of foetal development to projects. Depending on demand, some pregnant sheep are assigned to projects while others are maintained within the breeding flock for production of meat.

Animals used for breeding


A group of breeding pigs is located on a farm solely for supply of piglets for organ collection under an AEC-approved research project.

Animals in the breeding group (breeders and offspring)


A group of breeding cats is kept for supply of cats and kittens for use under an AEC-approved research project.

Animals in the breeding group (breeders and offspring)


A supplier produces fertile chicken eggs for supply to poultry farms to produce meat and for use in scientific procedures at day 11 of gestation (half gestation for a chicken is day 10.5).

Eggs past day 10.5 gestation assigned to projects involving scientific procedures

Multiple strains of genetically modified zebrafish are maintained in an aquatic facility to produce zebrafish larvae. Some of the female breeding zebrafish undergo ‘milking’ to collect eggs and some adult fish undergo tail fin biopsy for DNA testing. Some larvae are anaesthetised and immersed in various substances prior to humane killing at day four of embryological development, others at day nine.

Fish in the breeding group (breeders and offspring post day 7)

Fish assigned to research project past day 7 of development

A pregnant mammal, kept for the primary purpose of supplying animals for use in scientific procedures, is killed at a time point past half-gestation.

Pregnant female and all foetuses identified at the time of death of the female.

A rabbit is kept for the primary purpose of supplying animals for use in scientific procedures. She delivers six offspring, four live and two dead. Prior to weaning, one of the offspring is humanely killed as it is not required, the remaining three are retained as stock.

Seven rabbits – that being the female and six offspring (those found dead, those killed prior to weaning and those retained as ‘stock’)

This page has been left intentionally blank.

Animal Submission Guideline 2

awv report template · web view2020. 4. 29. · if the counting of neonates risks impact to...

Documents