b4901 ds v3 2020 83.xlsx - group · pure protein llc • 655 research parkway • suite 556 •...
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Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 1 .
sHLA–B*49:01B*4901, B4901, B*49, B49, B49
Serological Name B49
Peptide Load EndogenousModification UnmodifiedConjugation Unconjugated
SKU B4901
Product Description
Allele Name B*49:01
B2m
HLA Class HLA Class I
HLA Gene Locus HLA-B
Alternative Allele Name A Chain B*4901, B4901, B*49, B49, B49
Alternative Allele Name B Chain –
Description
Serological Name B49
Serological Split B21
Bw4/Bw6 Assignment Bw4
Bw4/Bw6 Sequence NLRIALR
Allele Frequency [World Population]
A chain 2.00%
B chain –
Associated products
B4901bioB4901pe
Product datasheet
Recombinant, truncated Class I soluble Human Leukocyte Antigen (sHLA), naturally folded and glycosylated, loaded with endogenous peptides.
Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 2 .
Product Specification
Product name HLA–B*49:01
HLA Species Human
Host Cell Line Species Human
Clone Designation D10F4
Tail Specification VLDL
Peptide Load Endogenous
Modification Unmodified
Conjugation Unconjugated
Complexity Monomer
Protein Format
Storage Temperature 4˚C (This product should be stored undiluted)
Form Liquid
Concentration 1000.0 µg/µl
Formulation PBS/0.02% Sodium Azide
pH 7.4
Purification Method Affinity Chromatography
Grade Research Use Only [RUO]
Authentication Verification Seqence Based Typing
Protein Sequences
Alpha Chain Sequence
Beta Chain Sequence
Related Products
A0201A0301A2402B0702
GSHSMRYFHT AMSRPGRGEP RFITVGYVDD TLFVRFDSDA TSPRKEPRAP WIEQEGPEYW DRETQISKTN TQTYRENLRI ALRYYNQSEA GSHTWQRMYG CDLGPDGRLL RGYNQLAYDG KDYIALNEDL SSWTAADTAA QITQRKWEAA REAEQLRAYL EGLCVEWLRR YLENGKETLQ RADPPKTHVT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDRT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRSVVSTDD DLA .
IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM .
Recombinant, truncated, soluble, non-modified, non-labeled, endogenously loaded
Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 3 .
Applications
HLA Sandwich ELISAs
HLA Direct ELISAs
HLA-Sera Antibody Assays
HLA Controls in ELISA Assays
HLA Assay Standards
HLA Blocking Assays
HLA Neutralizing Assays
HLA Competition Assays
HLA Bead Assays
HLA Immunization Procedures
Recommended Antibodies
W6/32
Anti-B2m
Allele Frequency
Please note: ALL PRODUCTS ARE FOR RESEARCH USE ONLY. NOT FOR COMMERCIAL USE IN DIAGNOSTIC PROCEDURES.For more information, please visit our Policies section on our website. For licensing inquiries, please contact
Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 4 .
Motif
Length Distribution
Please note: ALL PRODUCTS ARE FOR RESEARCH USE ONLY. NOT FOR COMMERCIAL USE IN DIAGNOSTIC PROCEDURES.For more information, please visit our Policies section on our website. For licensing inquiries, please contact
Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 5 .
Eplet Assignments B*49:01
Eplet Polymorphic Residues Antibody Reactivity
9H 9H12M 12M24T 24T32L 32L41T 41T Yes
45KE 45K46E Yes66I 66I
66IS 66I67S69TNT 69T70N71T Yes71TN 71T77N74Y 74Y
76EN 76E77N77N 77N80I 80I Yes
81ALR 81A82L83R82LR 82L83R Yes95W 95W97R 97R99Y 99Y
103L 103L113YN 113Y114N116L 116L131S 131S Yes152E 152E
152RE 151R152E156L 156L163L 163L
163LE 163L166E163LW 163L167W Yes193PI 193P194I