baby gene test
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Acid surprise
Ocean acidity is rising at least 10 times
faster than climate models predict,
according to eight years of daily
measurements off the Washington
state coast. It’s bad news for coral and
shellfish, which struggle to form shells
in acidic waters (Proceedings of the
National Academy of Sciences, DOI:
10.1073/pnas.0810079105).
Solar-powered slug
A sea slug has got into alternative
energy by stealing light-harvesting
components from plant cells and a key
gene that allows photosynthesis. This
enables the animal to survive without
normal food by gaining its energy from
the sun. The slug is arguably the first
known functioning plant-animal
hybrid (Proceedings of the National
Academy of Sciences, DOI: 10.1073/
pnas.0804968105).
Mars cache scrapped
NASA says that Mars Science Laboratory,
its next rover, will not help return
rocks and soil to Earth. The hope was
that the rover could stow samples until
a later mission brought them back for
closer scrutiny, but NASA is scrapping
the equipment that had been planned
for the job because its design is not up
to scratch.
Ebola evolves
A new species of Ebola virus has turned
up in Uganda. The DNA sequence of the
species Bundibugyo differs from other
Ebola viruses by about 32 per cent of
its nucleotide letters, a feature that
may complicate efforts to develop a
universal vaccine (PLoS Pathogens, DOI:
10.1371/journal.ppat.1000212).
Bad hairspray
Can hairspray lead to birth defects?
Paul Elliott of Imperial College London
and colleagues surveyed women often
exposed to hairspray when pregnant
and found their sons were more than
twice as likely to be born with a
genital birth defect called hypospadia
(Environmental Health Perspectives,
DOI: 10.1289/ehp.11933).
warm the globe this century.The car and truck emissions
caused the most warming: the first 20 years of warming caused by these emissions in 2000 is seven times as great as that generated by all the planes that criss-crossed the globe that year (Proceedings of
the National Academy of Sciences, DOI: 10.1073/pnas.0804844105).
“The study is very useful, valid, and necessary,” says Alice Bows of the Tyndall Centre for Climate Change Research in the UK. However, she underlines that the transportation mix is changing. For example, aviation is on the rise and is almost certainly contributing more to warming than it did in 2000.
A DROP of mum’s blood could soon reveal whether an unborn baby has a genetic disorder such as beta-thalassaemia or cystic fibrosis. Existing invasive tests carry a risk of miscarriage.
Babies only develop such diseases if they inherit two copies of the recessive gene responsible – one from each parent – and the new test promises to identify affected fetuses.
Dennis Lo of the Chinese University of Hong Kong and colleagues used a technique called digital PCR to count copies of the gene associated with beta-thalassaemia in blood samples from pregnant women, which contained fetal as well as maternal DNA. By noting ratios of recessive genes relative to normal copies of the gene, the researchers were able to work out if the fetus would develop the disease (Proceedings
of the National Academy of
Sciences, DOI: 10.1073/pnas.0810373105). They aim to do larger trials and test pregnant women known to be carrying the gene for cystic fibrosis.
Together with the non-invasive tests being developed for Down’s syndrome, the new test should reduce or even eliminate the need for amniocentesis and other invasive tests which carry a risk of miscarriage.
AS IF Zimbabwe didn’t have enough problems, the country is now facing an unprecedented outbreak of cholera as a result of its deteriorating infrastructure.
As New Scientist went to press, there had been nearly 9000 suspected cases and 366 deaths . The worst affected area is the capital Harare, where the local Ministry of Health has described the outbreak as “the biggest ever”.
Cholera is endemic in some of the rural areas of Zimbabwe and the last major outbreak was in 1992, when there were 3000 cases. Until recently, it was relatively rare in urban areas.
Now, run-down infrastructure, burst sewage pipes, water cuts and a lack of trained sanitation workers are forcing people to dig makeshift wells and defecate in public, increasing exposure to the water-borne disease. The onset of
the rainy season may flush more sewage into wells , exacerbating the problem.
Aid organisation Médecins Sans Frontières warns that up to 1.4 million people are at risk if the outbreak continues to spread.
“Run-down infrastructure and burst sewage pipes are forcing people to defecate in public”
Can NASA afford a shiny new generation
of robotic space missions?
The agency is developing the
brawny Ares V rocket to take astronauts
back to the moon. But it is also hopes
the rocket will double up as a heavy
lifter for robotic science missions which
the current shuttles are too puny to lift
off the ground. In the works, though
yet to be approved, are a visible-light
space telescope with an 8-metre mirror
that would dwarf Hubble’s, and an
interstellar probe that could explore
space beyond the boundaries of our
solar system.
But the huge price tags attached to
these proposals could make it very
difficult to scrape together the
necessary cash, says a report by a US
National Research Council panel . Many
of the missions will cost a minimum of
$5 billion each in today’s dollars.
“They are flagship class missions,
and if you look at what the NASA budget
is now for science missions, it doesn’t
seem like a lot of them would fit in that
budget,” says panel co-chair and former
shuttle astronaut Kathryn Thornton,
who is now at the University of Virginia.
Equally worried is former NASA
science chief Alan Stern, who argued
in The New York Times this week that
projects overrunning their budgets by
billions of dollars, like the James Webb
Space Telescope (pictured) and the
Mars Science Laboratory, are sharply
limiting the number and capability
of missions NASA can undertake, and
that they will continue to do so if not
brought under control.
GET A GRIP ON THE CASH, NASA
JWST
/NAS
A
–Eat your heart out, Hubble–
Baby gene test
Cholera strikes
www.newscientist.com 29 November 2008 | NewScientist | 7