becoming a pi – how do i get from here to there? philip norris bsri
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Becoming a PI –How do I get from here to there?
Philip NorrisPhilip Norris
BSRI
Success rates for R01 grants
0%
10%
20%
30%
40%
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
NIAID R01 success rates
New R01 (all NIH)
http://report.nih.gov/success_rates/index.aspx
Funding by submission #
0% 10% 20% 30% 40% 50%
SecondResubmission (A2)
First Resubmission(A1)
First (Original)Submission
http://report.nih.gov/success_rates/index.aspx
Average Age of New Investigators at Initial R01 Equivalent award
34
36
38
40
42
44
19
70
19
71
19
72
19
73
19
74
19
75
19
76
19
77
19
78
19
79
19
80
19
81
19
82
19
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19
84
19
85
19
86
19
87
19
88
19
89
19
90
19
91
19
92
19
93
19
94
19
95
19
96
19
97
19
98
19
99
20
00
20
01
20
02
20
03
20
04
MDMD-PhD
PhD
http://grants.nih.gov/grants/new_investigators/Average_age_initial_R01.xls
Case study of a PI start-up
PI support
$-
$50,000
$100,000
$150,000
$200,000
$250,000
2004 2005 2006
PI direct
PI indirect
PI total
Grant applications
0
1
2
3
4
5
6
2004 2005 2006
PI
Total
Publications during start-up
0
1
2
3
4
5
6
2004 2005 2006
First/last author
Total
Collaboration can save lives
Overall support increasing in spite of decreased PI awards
$-
$200,000
$400,000
$600,000
$800,000
2004 2005 2006
Overall direct
Overall indirect
Overall total
$-
$50,000
$100,000
$150,000
$200,000
$250,000
2004 2005 2006
PI direct
PI indirect
PI total
PI funding Total funding
Keep trying!
Grant applications
0
4
8
12
2004 2005 2006 2007 2008 2009
PI
Total
Extramural supportPI funding
$-
$400,000
$800,000
$1,200,000
$1,600,000
$2,000,000
2004
2005
2006
2007
2008
2009
2010
pro
jecte
d
PI direct
PI indirect
PI total
Extramural supportTotal
$-
$400,000
$800,000
$1,200,000
$1,600,000
$2,000,000
2004
2005
2006
2007
2008
2009
2010
pro
jecte
d
Overall direct
Overall indirect
Overall total
Publications
0
4
8
12
2004 2005 2006 2007 2008 2009 2010
First/last author
Total
Don’t spread yourself too thin
Diverse projects and funding streams
Funding sources HIVHIV -- CHAVI, CFAR,
WIHS WNV – NHLBI / NIAID MicrochimerismMicrochimerism – NHLBI TRALI – REDS /
SCCOR Pathogen reduction –
DOD / Industry Transfusion immunology
–NHLBI / DOD
HIV Immunology Immune correlates of protection Early HIV/SIV immunity
WNV Immunology CD4+ T cell epitope definition Treg quantification
Transfusion Immunology Defining immunology of
microchimerism Immune responses to transfusion TRALI / HLA antibody quantification Pathogen reduction effects on WBCs