Shared Pilot Facility to accelerate Innovation and Deployment of Industrial Biotech and Bioeconomy

BBI-JU info day

April 19, 2018

Kaunas, LT

Bio Base Europe Pilot Plant

Frederik De BruynBusiness Development Manager

Frederik.De.Bruyn@bbeu.org

Bio Base Europe Pilot Plant

Mission statement

To enable the transition to a sustainable

bio-based economy

Fossile resources

Chemicals

Products

Use

Waste

Energy

« Black »

CO2

from fossil to renewable resources: GHG reduction, re-industrialisation of EU, jobs, local resources

Deployment IB & Bio economy

• Research = turning money into knowledge

– Focus on lab environment and IP generation

– Process and DSP development typically lacking

• Innovation = turning knowledge into money

– Techno economical feasibility: Opex, Capex, LCA

– Market validation & value chains Prototypes

• Requirements

– larger infrastructure and hardware

– Expertise and skilled people

– Money & time

What’s missing?

Shared Pilot Facilities = risk sharing/reduction

– SPF play a key role in piloting disruptive technologies

– Bridging the valley of death for biobased processes

• Risky: uncertain political climate (CO2

taxes, incentives, … ) e.g. biofuels

• Low risk premium & longer payback

time: profit margins lower than in e.g.

pharma or red biotech

difficult to convince management

and/or private investors

About BBEPP

Multi-purpose pilot facility for bio-based products and processes

Fact and figures

– Independent service provider

– Operational since 2010

– 4 process halls

– Current number of employees: 70

– Bilateral projects: > 200 projects for > 100 companies

– Consortium projects: 19 projects ongoing, 15 projects finished

BBEPPA leading pilot plant for industrial biotechnology and bio-based products in Europe

BBEPP

Excellent location

In the heart of the Belgian bio-industry

EuroSilo

300.000 mT biodiesel

240 MWbio-electricity

200.000 m³ bio-ethanol

Biorefinery rodenhuize docks: the largest integrated production complex for biofuels in europe

A one-stop-shop

Pretreatment

Biocatalysis FermentationGreen

Chemistry

Downstream Purification

Examples

Corn stover

Paper pulp

Oils and fats

Husks, bran, straw

Agro Industrial by-products

Bagasse, beet pulp, seed press cakes

Algae

Non-food crops

Syngas

Defined media: glucose, sucrose, etc.

...

Bio-chemicals

Bio-based building blocks

Industrial Enzymes

Solvents

Polymers

Flavors and fragrances

Protein concentrates

Surfactants

Nutraceuticals

Fuels

Specialty carbohydrates

Services

• Concept design

• Fermentation optimization

• Downstream processing (DSP) development and optimization

• Techno-economic assessment (in-house developed model)

Process Development

• From 10 L to 15 m3 for fermentation + DSP, up to 50 m3 for other processes

• Generation of samples for application research

• Demonstration of technology at larger scale

• Pilot scale data (mass-and energy-balances, …)

Scale Up

• 1,5 m3, 4,5 m3 and 15 m3

• Fermentation

• (Solvent-)based DSP

• Biocatalysis

Custom Manufacturing

Process Hall 1

Biomass pretreatment, biocatalysis and DSP

Process Hall 2

Fermentations and DSP

Process Hall 3

Green chemistry and EX-proof DSP

Business ModelOpen Innovation Projects

Bilateral projects with industry

Consortia-based projects

• Bilateral, privately funded

• Intellectual Property remains with customer

• Over 200 projects for over 100 companies

• Partly subsidized, partlyprivately funded

• Building expertise

• Generates publicity andcommunication

• Independence

• Flexibility

• Confidentiality

ERA-IB & Horizon2020NANO3BIO - Production of chitosan

MARISURF - Marine biosurfactants

ERIFORE - Circular Forest Bioeconomy

REHAP - valuable compounds from forestry residues

DAFIA – Biomacromolecules from waste fractions for high value applications

NANOPACK - Pilot line production of functional polymer nanocomposites

FALCON – Enzymatic lignin degradation

SuperBio - Support and partnership in the bio-based economy

INTERREG projectsBioHArT - Technology for bio based renewable aromaticsBIOBASE4SME - Bio-Innovation Support for EntrepreneursSMARTPILOTS - Network shared pilot facilities for Bio EconomyIMPACT - Building new demonstration equipment for the development of IB

H2020 BBI-joint undertakingPULP2VALUE - sugarbeet pulp into value added productsCARBOSURF - biosurfactants & specialty carbohydratesDEMETER - enzymes for anaerobic digestionReSolve - REnewable SOLVEnts with high performance and improved toxicity profilePilots4U - A Network of Bioeconomy open access pilot and multipurpose demo facilities

CONSORTIA-BASED PROJECTS:Technology development, scale up and

building new value chains

Valorization of Sugar Beet Pulp

Role of Bio Base Europe Pilot Plant

Process Testing and Optimization, Addressing Technological Hurdles,

Validation of Integrated Process Routes at Ton Scale

Partners

Pulp2Value

www.Pulp2Value.eu

Partners

resolve-bbi.eu

REnewable SOLVEnts with high performance in application and improved toxicity profile

A Europe-wide network of existing

open access pilot and multipurpose

demo-infrastructures for the bio-

economy

Pilots4U project aim

Project aim: Setup of one very visible,

Europe-wide network of existing open

access pilot and multipurpose demo-

infrastructures for the bio-economy

Pilots4U network: what is open access

In the context of infrastructure, open access

involves physical infrastructure (in this case

pilot equipment) being made available to

clients other than the owners, for a fee (Source: Wikpedia)

Joint investment in pilot infrastructure that

can be used, for a fee, by any entrepreneur

in need of scale-up

Why outsource your development and

scale-up? – Survey results

1. Faster: Accelerated development: faster time to markt

2. Cheaper: Saved development costs

3. Better: Improved characteristics of the process or final product

4. Stronger: Improved network

What bioeconomy pilot equipment?

Algal

cultivation

Industrial

Biotechnology

Chemical

Conversion

Fractionation

Purification

Anaerobic

digestionPulping

Thermal

conversion

Material

technologies

Nutrient

recovery

Take a look at the Pilots4U asset database of pilot equipment

https://www.biopilots4u.eu/asset-database

Did you already fill in our survey?

https://www.biopilots4u.eu/survey

Have you brought a bio-based process towards

commercialisation or want to?

We need your input!

Questions?