biodbnet abcc! · prinng: your,printer,might,not,print,the, same,way,our,printers,do,,so,...
TRANSCRIPT
Prin%ng: Your printer might not print the same way our printers do, so make sure to try a couple of test prints. If things aren’t aligning quite right, experiment with the Scale to Fit Paper seCng. It’s located in the Print dialog – just click Full Page Slides to get to it.
And did you no%ce we made fold marks for you? They are really light, but if you don’t like them showing on your brochure, click View, Slide Master, and delete them before you print.
Customizing the Content: The placeholders in this brochure are formaNed for you. If you want to add or remove bullet points from text, just click the Bullets buNon on the Home tab.
If you need more placeholders for %tles, sub%tles or body text, just make a copy of what you need and drag it into place. PowerPoint’s Smart Guides will help you align it with everything else.
Want to use your own pictures instead of ours? No problem! Just click a picture, press the Delete key, then click the icon to add your picture.
If you replace a photo with your own and it’s not a flawless fit for the space, you can crop it to fit in almost no %me. Just select the picture and then, on the Picture tools Format tab, in the Size group, click Crop.
Core Infrastructure and Systems Biology
Advanced Biomedical Computing Center
Information Systems Program
Frederick National Laboratory for Cancer Research
http://ncifrederick.cancer.gov/isp/abcc
[email protected] 301-846-6774
http://biodbnet.abcc.ncifcrf.gov
bioDBnet ABCC
ISP, FNLCR
• Convert across biological identifiers – 200 biological identifiers across 50 databases including EntrezGene, UniProt, RefSeq, Ensembl, DrugBank, OMIM, HMDB, Affy, dbSNP…
• Functional annotations – GO annotations, KEGG, Reactome, Biocarta
• Conversions across species – mouse affy probe id to human pathways
• 1000’s of users across the world
• Integrated into EBI’s BioServices
Mudunuri et. al., Bioinformatics 2009 (PMID: 19129209)
bioDBnet
proteomics
genomics
metabolomics methylation
protein disease drug
interaction
microarray probes
functional annotation
protein feature
taxon
pathway gene
orthologs
variation
transcriptomics
Data Mining • Mine from multiple formats • Species agnostic conversions • Biological data warehouse • Variant Impact Analysis • Species agnostic conversions • Large scale data integration • SQL and NoSQL • Literature Mining
Systems Biology • Disease agnostic queries • Clinical and genomic integration • Multi-‐omics data integration • Analysis on longitudinal data • Secure role based access • Data sharing across collaborators
Prin%ng: Your printer might not print the same way our printers do, so make sure to try a couple of test prints. If things aren’t aligning quite right, experiment with the Scale to Fit Paper seCng. It’s located in the Print dialog – just click Full Page Slides to get to it.
And did you no%ce we made fold marks for you? They are really light, but if you don’t like them showing on your brochure, click View, Slide Master, and delete them before you print.
Customizing the Content: The placeholders in this brochure are formaNed for you. If you want to add or remove bullet points from text, just click the Bullets buNon on the Home tab.
If you need more placeholders for %tles, sub%tles or body text, just make a copy of what you need and drag it into place. PowerPoint’s Smart Guides will help you align it with everything else.
Want to use your own pictures instead of ours? No problem! Just click a picture, press the Delete key, then click the icon to add your picture.
If you replace a photo with your own and it’s not a flawless fit for the space, you can crop it to fit in almost no %me. Just select the picture and then, on the Picture tools Format tab, in the Size group, click Crop.
Systems Biology
Omics Analysis
Protein Features
Bioquery Medline
AVIA • Impact assessment
• Clustering and Functional Annotations
• Genomic and Protein positions as input
• Visualize tissue expression levels, pathways, 3D structures, Circos plots
• Prioritize and Summarize Variants and Genes
http://avia.abcc.ncifcrf.gov
Vuong et. al., Bioinformatics 2014 (PMID: 24215028)
• Role based secure data access
• Data type aware browsing
• Disease agnostic
• Integration of omics data
• Clinical and genomic data integration
• Longitudinal analysis
• Dynamic pathway and functional analysis
• Applicable for multi-omics data sets
• Query based on protein names or amino acid positions
• All protein features from UniProt
• Visualization using BioJS
• Customizable user defined features
• Clinical and genomic data integration
• Query using gene symbols
• Dynamic filtering options on known drug/disease/pathway associations
• Visualize co-author networks