biodisrupt 2019: amyris overview€¦ · of the world’s leading personal care and beauty brands...
TRANSCRIPT
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BioDisrupt 2019: Amyris OverviewMay 16, 2019
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Cautionary Notes
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Cautionary Notes
FORWARD-LOOKING STATEMENTS
This presentation and oral statements accompanying this presentation contain forward-looking statements, andany statements other than statements of historical fact could be deemed to be forward-looking statements. Theseforward-looking statements include, among other things, statements regarding future events, such as expectedrevenue, gross margin and production volume in 2019, including related growth rates, the anticipateddevelopment, scaling and commercialization of Amyris’s product pipeline and introduction of new products,including HMOs and cannabinoid ingredients, expected growth of Amyris’s Clean Beauty business, the anticipatedsize of the global beauty and personal care market, including categories thereof, as well as Amyris’s entry intocertain of such market categories, including the timing thereof, and expectations regarding Amyris’s financial andoperational results and ability to achieve its business plan in 2019 and beyond. These statements are based onmanagement’s current expectations and actual results and future events may differ materially due to risks anduncertainties, including risks related to Amyris’s liquidity and ability to fund operating and capital expenses, risksrelated to potential delays or failures in development, production and commercialization of products, risks relatedto Amyris's reliance on third parties, and other risks detailed from time to time in filings Amyris makes with theSecurities and Exchange Commission, including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Qand Current Reports on Form 8-K. Amyris disclaims any obligation to update information contained in theseforward-looking statements, whether as a result of new information, future events, or otherwise.
Copyright © 2019 Amyris, Inc. All rights reserved
© 2018 Amyris, Inc. All rights reserved. Confidential & proprietary.
BioDisrupt Conference Agenda – May 16, 2019
9:30am Amyris Main Presentation
10:25am Clean Beauty Movement
11:20am Amyris Technology Roadmap & Product Pipeline
11:50am Lunch Break
Note: Your lunch location is designated on the back of your nametag
12:50pm Chinese Market and Consumers
1:20pm Cannabinoid: The Future of Pain Management, Anxiety, and Better Sleep for All
1:55pm Amyris Closing
2:00pm R&D Tours and Product & Sample Tent – Group A
3:00pm R&D Tours and Product & Sample Tent – Group B
Note: Your tour number is designated on the back of your nametag
4:00pm Gift Bags & Conclusion
3Copyright © 2019 Amyris, Inc. All rights reserved
4Copyright © 2019 Amyris, Inc. All rights reserved4
• The leading pipeline in our
industry:
� Cannabinoids
� Vitamins
� HMOs
• Leadership in
NoCompromise™ natural
products
• Proven technology platform
• Market leader in F&F Ingredients,
Clean Skin Care & Zero Calorie
Natural Sweetener
FERMENTATION
MAKES NATURAL
SUSTAINABLE
Copyright © 2019 Amyris, Inc. All rights reserved 5
From Idea To Industrial-Scale, Making Natural Sustainable
1 Engineer microbial factories
Emeryville, CA, USA
(near San Francisco)
2Produce ingredients using our industrial fermentation technology
Brotas, Brazil
CMOs
3Commercialize through collaboration partners and direct to consumer
Formulate and sell own products
Copyright © 2019 Amyris, Inc. All rights reserved 6
Copyright © 2019 Amyris, Inc. All rights reserved
Sources: Leffingwell & Associates article on 2013-2017 Flavor & Fragrance industry leaders.
Estimates are as of Aug 2018. Also published on July ‘18 edition of Perfurmer & Flavorist
** Results for Sensient Flavors & Fragrances excludes all non F&F items
Note - Using Mane's internal actual average exchange rate they reported the U.S. dollar equilalent as USD $1,306.9 million for 2017 and as USD $1,172 million in 2016 and as USD $1,051 million in 2015
Note - We have restated Takasago's sales figures for 2013-2017 to eliminate certain revenue items such as non F&F fine chemicals such as pharmaceutical intermediates as well as real estate revenues.
(1) Market Share is based on U.S. dollar values
(3) Accounting Period of July 1 to June 30
(4) Accounting Period of April 1 to March 31
(5)Accounting Period of Oct. 1 to Sept, 30; Net sales given are Company consolidated sales, See T.Hasegawa Co., Ltd.
(6) Accounting Period of Sept. 1 to August 31 until year 2000
(7) ** See also Note (6). F&F figures in the tables for 2000-2013 for Sensient Flavors &Fragrances
Amyris partners with the leading companies in the industry
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Company Rank Est. 2017 Sales USD$ Market Share
1 Givaudan $5,132.80 19.50%
2 Firmenich $3,668.40 (est) 13.9% (est)
3 IFF $3,398.70 12.90%
4 Symrise $2,672.60 10.20%
5 Mane SA $1,306.10 5.00%
6 Frutarom $1,271.40 4.80%
7 Takasago $1,185.40 4.50%
8 Sensient Flavors $618.80 2.40%
9 Robertet SA $570.00 2.20%
10 T. Hasegawa $428.10 1.63%
0
5
10
15
20
25
30
35
40
45
Product 1Product 1Product 1Product 1 Product 2Product 2Product 2Product 2 Product 3Product 3Product 3Product 3 Product 4Product 4Product 4Product 4 Product 5Product 5Product 5Product 5
Mo
nth
sM
onth
sM
onth
sM
onth
s
From first strain to first pilot run
Lower average product
development cost.
90%
Bigger pipeline,
powered by 20%
increase in headcount
500%
Accelerating Disruption
Lower average time
to market.
80%
2012 2019
Copyright © 2019 Amyris, Inc. All rights reserved 8
Molecule Profile From Launch
Source: consumption per value share reports and/or distributor data 9 Copyright © 2019 Amyris, Inc. All rights reserved
Molecule 2
CAGR : 56%
Molecule 1
CAGR : 85%
Note: 2018 Actual vs.2019 Plan Volume
Our Platform Is Delivering
Farnesene Derived Fragrances ’18- ‘19 Growth
Molecule 1 214%
Molecule 2 scaling up in 2019
Farnesene Derivatives ‘18-’19 Growth
Molecule 1 129%
Molecule 2 301%
Molecule 3 163%
Fermentation Molecules ‘18-’19 Growth
Molecule 1 175%
Molecule 2 scaling up in 2019
Molecule 3 scaling up in 2019
Molecule 4 Flat
Molecule 5 2000%
Molecule 6 422%
Molecule 7 5800%
Molecule 8 67%
Branded Product Sales
+277%
Ingredient Sales
+61%
2016-2019 REVENUE CAGR
Copyright © 2019 Amyris, Inc. All rights reserved10
Advantaged Portfolio Delivers Strong Growth & Expanding Profitability
2018 20192017
* Adjusted for loss making product sales on contracts and one time revenues
Gross Margin % 49% 52% 55%- 65%
11 Copyright © 2019 Amyris, Inc. All rights reserved
Product
License/Royalties/Collab
OUR BIOSSANCE
BRAND IS
NO COMPROMISE
BEAUTY™
In the U.S., the standards for ingredients allowed in beauty products
are shockingly low—with only 11 banned ingredients.
At Biossance, we draw on our rich history of science and
sustainability to create skincare products that are good for you and
good for the planet.
We formulate with a No Compromise™ approach, setting the bar
higher for both safety and performance.
12 Copyright © 2019 Amyris, Inc. All rights reserved
Biossance Key Growth Indicators (Jan 2017-April 2019)
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Fastest growing Clean Skincare brand in North America.
Powered by Squalane.
Copyright © 2019 Amyris, Inc. All rights reserved
2012 2013 2014 2015 2016 2017 2018 2019
3000+ Brands
Copyright © 2019 Amyris, Inc. All rights reserved
14
Source: Aprinnova Distributor Data
Neossance™ Squalane Growth
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Global Skincare market breakdown (2017, $B) Skincare market distribution channels (2017, $B)
1 – Euromonitor 2017
Copyright © 2019 Amyris, Inc. All rights reserved
Beauty & Personal Care Market
Beauty & personal care global market sizes by HPC category (2017, $B)
© 2019 Amyris, Inc. All rights reserved.
Amyris Sweetener Is What Consumers Want
• Diabetes and obesity is rising
• Second-rate taste offerings no longer cut it
• Millennials are demanding pure and natural
• Amyris has the best tasting, most sustainable and purest natural sweetener
16Copyright © 2019 Amyris, Inc. All rights reserved
17Copyright © 2019 Amyris, Inc. All rights reserved
18Copyright © 2019 Amyris, Inc. All rights reserved
Brazil LaunchFall 2019
US LaunchEnd of 2019
Upcoming purecane™ Launches
© 2019 Amyris, Inc. All rights reserved.
• Amyris is the known leader in successfully serving high-growth global markets with fermentation derived, naturally-sourced, sustainable ingredients
• Entering cannabinoids market with proven platform and ability to develop, scale and commercialize ingredientso Executed $300 million development, licensing and commercialization agreement with
additional long-term royalty stream.
• In partnership with DSM, Amyris is moving quickly toward the commercialization of its first Human Milk Oligosaccharide (HMO) molecule, which is in the family of sugars from mother's milk. At the pace we’re moving, we'll have more than one to commercialize.
Product Pipeline – Cannabinoids, Vitamins, and HMO’s for Human Health
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Source: NY TimesConcept and diagram by Paul Sahre. Photo illustration by Jamie Chung. Prop styling by Anna Surbatovich.
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Can CBD Really Do All That?
Promotes Recovery from
Opioid Addiction
Speeds Recovery From Workouts
Lowers Blood Sugar
Lessens Arthritis Pain
Prevents Anxiety
Calms Dogs
Relieves Menstrual Cramps
Helps You Sleep
Slows Alzheimer's Dementia
Curbs Anger
Reverses Depression
Slows Parkinson’s
Treats Crohn’s Disease
Cures Cancer
Stops EpilepsyHeals Brain InjuryHeals PTSD
Halts Psychosis
CBDs For Pain Management, Not Opioids
21Source: US Department of Health and Human Services
Make good.No compromise.
• Our ingredients are inside over $7B of consumer retail purchases
• You’ll find our ingredients in over 3,000 of the world’s leading personal care and beauty brands
• Our Biossance Skin Care Brand is the fastest growing Skin Care Brand in North America
• We have the leading product into the natural Sweetener market. We want to replace sugar & are committed to a healthier planet! We want to help reduce risk of Diabetes and Obesity….
• Most profitable product portfolio in the industry
Good for People
Good for the Planet
Good for Business
™
22Copyright © 2019 Amyris, Inc. All rights reserved
Amyris Awards Won Since BioDisrupt 2018
Product Won:Biossance Squalane
+ Mineral SPF 45
Product Won:Biossance Squalane
+ Peptide Eye Gel
Product Won:Biossance Squalane + Tea Tree Cleansing Gel
Product Won:Biossance Squalane +
Glycolic Renewal Facial
Product Won:Biossance Squalane + Tea Tree Balancing Oil
Category Won:Best Manufacturing &
Processing Technology
Copyright © 2019 Amyris, Inc. All rights reserved
24Copyright © 2019 Amyris, Inc. All rights reserved