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HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 [email protected] • www.HarvestPlus.org Biofortification: achievements and challenges Erick Boy-Gallego Ascona, Switzerland (May 24, 2015)

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Page 1: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 [email protected] • www.HarvestPlus.org

Biofortification: achievements and

challenges

Erick Boy-Gallego Ascona, Switzerland (May 24, 2015)

Page 2: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org
Page 3: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Vitamin & Mineral

deficiencies: 2

billion persons

affected Miracles in Action.org

Page 4: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Supplementation: tablets, pills, etc. Fortification

Agriculture: Biofortification The process of increasing vitamin & mineral densities of edible parts of staple food crops (Jeong and Guerinot, 2008)

Dietary Diversity

Complementary Strategies

SAFE WATER INFECTION CONTROL & PREVENTION

BREAST FEEDING & COMPLEMENTARY FEEDING DEWORMING

Page 5: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

What is biofortification?

Zinc

Iron

Pro Vitamin A Carotenoids

India

Rwanda & DRC

India & Pakistan

Bangladesh

Nigeria, Zambia Uganda DRC

• Increases staple crop nutrient concentration without sacrificing agronomic traits (i.e. yield, pest resistance, drought resistance)

• Plant transformation (selective breeding, bioengineering), agronomic management.

• HP focuses on iron, provitamin-A carotenoids, zinc

Page 6: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Letting nature do the work

Page 7: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Cost-effective: single up-front investment in R&D (social good)

Page 8: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

“If you had $75 billion for worthwhile

causes, where should you start?”

1. Bundled micronutrient interventions to fight hunger and improve

education

2. Expanding the Subsidy for Malaria Combination Treatment

3. Expanded Childhood Immunization Coverage

4. Deworming of Schoolchildren, to improve educational and health

outcomes

5. Expanding Tuberculosis Treatment

6. R&D to Increase Yield Enhancements, to decrease hunger, fight

biodiversity destruction, and lessen the effects of climate change

http://www.copenhagenconsensus.com/sites/default/files/outcome_document_updated_1105.pdf

“One of the most compelling investments is to get nutrients to the world’s undernourished. The benefits from doing so

– in terms of increased health, schooling, and productivity – are tremendous.”

Among the top 16 priority solutions, “Fighting malnourishment should be the top priority for policy-makers

and philanthropists…”

Page 9: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Niche target: rural subsistence farming families, particularly women and children

Page 10: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Sustainable for producers

Page 11: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

DOES BIOFORTIFICATION

WORK?

Page 13: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Nutrition Research to Date (April 2015)

Intake & nutritional status

Retention Absorption Efficacy Effectiveness

OFSP

MAIZE

CASSAVA

BEANS

PEARL MILLET

RICE

WHEAT

Complete:

VA Fe Zn

Page 14: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Nutrition Research to Date (April 2015)

Intake & nutritional status

Retention Absorption Efficacy Effectiveness

OFSP

MAIZE

CASSAVA

BEANS

PEARL MILLET

RICE

WHEAT

Complete:

VA Fe Zn

Page 15: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Nutrition Research to Date (April 2015)

Intake & nutritional status

Retention Absorption Efficacy Effectiveness

OFSP

MAIZE

CASSAVA

BEANS

PEARL MILLET

RICE

WHEAT

Complete:

VA Fe Zn

Page 16: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Nutrition Research to Date (April 2015)

Intake & nutritional status

Retention Absorption Efficacy Effectiveness

OFSP

MAIZE 2

CASSAVA 2

BEANS 3

PEARL MILLET

2

RICE

WHEAT 2

Complete:

VA Fe Zn

Page 17: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Nutrition Research to Date (April 2015)

Intake & nutritional status

Retention Absorption Efficacy Effectiveness

OFSP

MAIZE 2 2016-18

CASSAVA 2

2016-18

BEANS 3 2 2015-17

PEARL MILLET

2 2016-18

RICE 2016-18 2018-21

WHEAT 2 2014-15 2016-19

Complete: Active:

VA Fe Zn

Page 18: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Nutritional Impact: RCTs

• High Iron Beans: increased hemoglobin and total body iron

• High Iron Pearl millet: prevalence of iron deficiency reduced; cognitive improvement in schoolers

• Orange sweet potato: increased vitamin A intake, improved status, reduced prevalence and duration of diarrhea

• Orange Maize: increased vitamin A stores; visual adaption to darkness

• pVAC Cassava: improved vitamin A status

• High Zn Wheat: nearly 70% more absorbed zinc than control wheat

Page 19: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Target Countries and Crops

More than 2 million farming households reached by HarvestPlus.

Crops released are high-yielding with climate smart traits.

Page 20: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Cassava

Vitamin A

Nigeria & DRC

Beans

Iron

Ruanda & DRC

Maize

Vitamin A

Zambia

Varieties released in Africa and South Asia

2007

Sweet Potato

Vitamin A

Uganda

Pearl Millet

Iron

India

Rice

Zinc

Bangladesh

Wheat

Zinc

India | Pakistan 2015

2013

2012 2013

2012 2011

2013

2012

Page 21: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Released varieties in 27 countries

18 in Africa, 4 in Asia, 5 in LAC

Under development in 43 countries

26 in Africa, 8 en Asia, 9 in LAC

4 Vit-A , 5 Iron, 4 Zinc

Sorghum Banana

Plantain Cowpea Potato

Lentil

Page 22: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

High-Level Support - Policymakers

Page 23: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org
Page 24: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org
Page 25: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org
Page 26: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Empowering women farmers

Page 27: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Uganda OSP scaling up: Start up process

• Choosing areas of implementation – able to support both crops

• Choosing implementing partners with food and/or nutrition security projects

• Select farmer groups (FGs)

• Sensitization process on the nutritional benefits of the crops

Page 28: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Implementation Areas

World Vision

VEDCO

CEDO

Caritas

MVP & HCU

Africa 2000 Network

Samaritan’s Purse

Page 29: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Implementation structure

• Mostly introduce nutrition into Agric extension system

• Use both paid and voluntary extension agents

• Training conducted down that structure to the farmers

Extension worker

Farmer Rep

Farmer Gp

FG FG

Page 30: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Using government structures

Agric extension system

District

Sub/county

Farmers

Health extension system

Health centre

VHTs

Patients

Page 31: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Dissemination through Schools

• Schools targeted have land and agriculture programs

• Pupils sensitized on nutritional importance of crops

• Pupils given planting material to take home

• Biofortified crops prepared for school meals

School

Hhs

Hhs

Hhs

Hhs

Page 32: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Activities

Seed systems

• Agronomy training:

– Planting,

– Pest and disease management

– Post harvest handling

Page 33: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Activities cont’d

Demand Creation

• Nutrition training

• Drama

• Radio

• Field days

Page 34: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Activities cont’d

Marketing and Product development

• Training in marketing

• Linking farmers to traders

• Product development

Page 35: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org
Page 36: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Scaling Biofortified Nutritious Crops: the

biofortification priority index (BPI)

http://www.ifpri.org/tools/bpimappingtool

Page 37: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

The road ahead for a common good

Maize (Zambia) and pearl millet (India) trials with CU2Y

Multiple biofortified crops (food basket) approach for the life cycle (Complementary feeding, Mumbai)

Page 38: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

The road ahead for a common good

• Lower phytate crops (lpa beans) and high minerals GM rice: further breeding and bioavailability testing (ETH, IRRI)

• Zinc biomarkers development: validation of intracellular biomarkers of Zn status (CHORI/ETH/St. Johns Research Center)

• Post harvest food processing: product quality through value chains in target countries

• Information translation and sharing across HP, CG centers, country and international stakeholders…

Page 39: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Purple tomatoes high in anthocyanins

http://news.bbc.co.uk/2/hi/health/7688310.

stm

Tearless Onion Dr Eady

Crop & Food Research in New

Zealand and his collaborators in

Japan

Page 40: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Industrial Food Fortification

Nutrition- sensitive agriculture:

Biofortified Crops, Homestead FP

Public Health Interventions

Dietary Diversity

Supplements

Behavior Modification

Context-specific sustainable, effective mix of

options addressing immediate and underlying

causes with a life cycle approach

• Empowering

women

• Education

• Income

generation

• Delivery

platforms

Page 41: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

KEEP INNOVATING AND INTEGRATING

"We are guilty of many errors and many faults, but our worst crime is abandoning the children, neglecting the foundation of life. Many of the things we need can wait. The child cannot. Right now is the time his bones are being formed, his blood is being made and his senses are being developed. To him we cannot answer "Tomorrow". His name is "Today"." Gabriela Mistral, 1948

Page 42: Biofortification: achievements and challenges · HarvestPlus c/o IFPRI 2033 K Street, NW • Washington, DC 20006-1002 USA Tel: 202-862-5600 • Fax: 202-467-4439 HarvestPlus@cgiar.org

Thank You!