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    Biological RelativesSARAH FRANKLIN

    IVF, Stem Cells,

    and the

    Future of Kinship

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    SaRah FRanklin Bc Rvs

    iVF, S Cs,

    Fr f ksp

    De Ue Pe Dh L 203

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    203 De Ue Pe

    A h eee

    Pe he Ue Se Ae -ee ppe

    Ce ee A Rh Bh. Ie Ce Leh Be

    Tpee Wh D Te I Se, I.

    L Ce C--P D

    , Sh, 960

    B ee : ivF, e e, he e hp / Sh .

    pe (xpee e)

    Ie ph eeee ex.

    isbn 978-0-8223-5485-7 (h : . ppe)

    isbn 978-0-8223-5499-4 (p. : . ppe)

    . ez , HS pe. 2. KhpPhph.3. e hp. i. Te. ii . See: xpee e.

    r35.F74 203

    68.78059923 20308962

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    To Pat Spallone, who stayed

    with the rouble, and has always

    found the words.

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    ContentS Acknowledgments x

    introduction

    Ree B

    1 Me Be 3

    2 L T 68

    3 Pee 02

    4 Repe Tehe 50

    5 L ivF 85

    6 ivF Le 22

    7 e Ce 258

    8 Ae ivF 297

    aFtErword 3

    Notes 33

    References 333

    Index 35

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    aCknowledgmentS

    ndn or the reserh ondted n the book ws enerosly proded he S Reeh C (Se Ce Ie) he

    Wellome Trst (Medl Hmntes). Wthot the lon-stndn spport

    eee Pe Pee Be, e he e h

    pje he ee ee he e G Hp L-

    . D. D I, he e he he PS e e G,

    D. Sephe, h epe he e, ep,

    he e e G, ee h ee h he e

    pe h he exp he he . Ge Ce, D. Y- Khe, D. A Lh, D. V W he ee -

    nly helul oer many years as my research mrate rom pgd to stem cells.

    I p I e h he G Ge p-

    hh p he pje, The Art of

    A.R.T., n the Guys Assste Conceton Unt, but also or allown the maes

    e epe h e, e h .e.

    .hp. I ee he h e p

    ths manuscrt, nclun Karn Lesnk-Obersten, Nck Howoo, Chrstna

    Brndt, Donn Hrwy, Steenn De Slle, Brbr Orlnd, nd Zeynep

    G, he ee h he p peee, pe

    e . I he hee exe eee h e he

    p ee, e ee hep ee, I epe-

    e S Ahe M She, h e he pee

    p--pe ee ee eee e -

    e e e p he eepe Biological

    Relatives. Th M, M Pe, T De, h he

    e he Ie he H he P Kee

    eeh ee 20082009 nyu. Thh he h -

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    x acknowlEdmEnts

    scrt I hae ha the benet o workn closely wth Proessor Martn Johnson

    D. N Hp Ce Ue pje e

    he h eepe he U.K., pehp

    h he Gee Rep pje Ce. H e

    Ce e he pe Biological Relatives, I he eee ee he qe e epe e hee

    n more wys thn wold be possble to desrbe deqtely here, nd t s

    hpe h h ehe he ee

    h h ep ee. Le j pje, h

    e h p , I eep ee pe S

    Ahe he pp, eee, e. A ee, he De e

    h ee pe, e, eh, he

    stewrdshp o the mnsrpt nto prnt. Spel thnks to Ken Wssoker,Je B, Lz Sh, A Bh e epe

    ee e he e p. I h pee pee e p he

    De , h he ee he. , I

    e h e e e P Spe, h h ee h e he

    je h ee e he e.

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    intRoduCtion Rvy Bc

    Th-e e e e eh eh ep, e e e e, ez-

    (ivF) h px e. Se e -

    e 978, ivF h p ee e e , he

    t the sme tme lso beomn, s Ale mht he sd, roser nd

    e. Cep e, e h pe

    hh he ivF, ehe h ep ep-

    e qe he e. A he h, h ep

    now be looked tnd not only throh the mrosope. The moment oep e ee he Iee; epe e-

    ee, h he ee e. I e e 3d

    YTe. Th ehz ep h .

    Thee e efe he ee e h ee

    he e , eq he ee -

    p , h h e e . Wh e e

    h ivF h ee hh hh e ee ee? Wh

    e e he eh ep h ep-

    p pee? Wh pee eh ivF? Ae ,

    j e , peehe p ivF pe

    e h e.

    I efe p he e e e ivF, e e he

    e ivF eh h h h pex e he

    h he e ee pe, hh

    e eee h he hz e eeee ee

    e e ee. expee eeh ehqe e e-

    bryoloy, ivF has eole nto a lobal technolocal latorm, use or a we

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    2 introduction

    e pp, ee e ee -

    e e eeh. Oe e he h ivF

    ehqe h h e hh ee, ee, e

    p e pex he ep-

    ucton. rom ths ont o ew, the hstory o ivF s that o a stem technoloyh h ee ee e h e he e he -

    cal that so stnctly characterze the twenteth centurya moel technque

    e e.

    A h, ivF e he h he pe e

    ox Keller (2002) desrbes s mkn sense o le proess tht, lke

    ivF, hs lso beome roser nd roser oer tme. As Jne Men-

    he (2003) e, ivF h he e e h e

    qe h ee h p e e e h. Se he ee ep e ez , h he e

    he e eeeh e Jqe Le e h, ee pe-

    csely esne not only to control le, but to reene t. Loebs scoery that

    eg e expee e h pe, he -

    eepe , exp ee e e

    o le s mehnl, nd ths reenneerble. As Menshen ponts ot,

    Le, h p ee e, h e qe h e

    e e (2003: 79). A e x Kee ee, hpe h e e je pee hh he ep

    p, ee ppe, heze pe-

    ty. As Keller notes, the eort to dene wht le s ben only two en-

    e h Je-Bpe L e e e h

    e p h h e e, eee h

    e , eee. A Kee e, B he ee ee

    he qe he e eee e, e ee pe,

    h ee he e he eee -

    , ephz h he pe h e, h qe

    or les essence smultaneously works towar ts ssoluton (2002: 292). As

    Kee e he, he pe pe e e he e-

    e h e h pe-L, e eheeh-

    e he ex pje h he , hh e

    med to demonstrte tht the border between le nd nonle s entrely

    p h e e h p.

    I ee, h h e e he he he,

    he, hh hh p e -

    e pe. The e he heze

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    rElativEly bioloical 3

    ee ee he, h eq p-

    he e .

    The ee pe, Kee (2002) ee , he h

    e e pee epe ivF, hh h ee e he e e-

    eh ehqe e he hez e e ppe-tes n the pst, nd ontnes to shke them p n the present. Lke Loeb

    n the nneteenth entry, Shny Ymnk nd hs tem n Kyoto dso-

    ee e he e e pe -

    p e eee e he pe-

    derentted stte proess tht s kn to mkn ble deelopn

    embryo wthot ether sperm or eg. They seeded n me n 2006 nd

    h e 2007, h e pee ppe e (PS)

    eh e ee e eh p eeh he pee eh e eepe (Thh Y-

    2006). Th p he

    eeh-e ee h epe e ehqe

    expe he pe eepe e, Kee

    p , he e ep e expe (h e ee).

    Ahe pe h pe e he e ee -

    h h ee epee ehe he ep

    dene wht le s, espelly now tht boloy s tsel nresnly nder- eh h eh h e e. Th

    h ee eh eph ep: e PS e,

    rses re sed to trnsport the reqred enes, nd the enes, or tors,

    heee ee he pe e eze e.

    Iee, he e pee eeee he -

    e q pee h

    eh h ee.1 B hee e e he -

    ouser an curouser moment, as ths also means that technoloy s becomn

    e ze. A h h e ee p pe

    ivF h e h pe, epe , e e

    h e pee e, h. I ez

    s t one tehnqe, model, n mtton o bolol proess, syn-

    he pe, e eeh eh, , e

    h ep e. I expee e e

    h e h e e . Ceqe, e h ivF

    h e e e h ee h e e

    ee.

    Th hh he h , hh e h he

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    4 introduction

    h ivF, ze pee, ep e ee

    sense o ths tehnqe both n nd o tsel nd s prt o wder proess

    hh hh he h ee e exp ee .

    I desrbe ths s the emerene o bolol reltty, whh s explored

    h he p e ivF, h ehqe e e h e e eh,

    eh . I ge h he he

    he eh h p h e he qe e ivF

    e, h ivF e qe pepee hh e hee -

    p e ee , (e I.). M

    h h h ivF

    as by holn t stllusn t as a sh moel o tsel, chann the lters, the

    eph e, he h.I ez h epe peze e pe

    throuh whch boloy s not only enaturalze but culture u. Whle con-

    expee , ivF eh eee

    ze ze hp, peh, ep:

    pe he hpe e hee. I h e e ee

    he e h ehe h ee

    hhly poplr nd sessl re qkly tken or rnted (ndeed, ths s

    h e ehe e ee). B h pehe eh ee, R W e, -

    trl ormoten ssoted wth new sol nd nstttonl norms, nd

    h ze. W e e eh he ehe

    ee pe h e epe h ee,

    e pe ex (990: 2)

    nto ont both the ntentons tht proded t nd ts hnn role s

    t eoles oer tme. In ths wy he hllenes the sterle opposton be-

    ee he e eh ehe eee h e,

    ee ehe e ee. Ie he e e-

    h he e he ee ehe pe p

    lrer wholes, wthn whh tehnoloy s not, n hs words, solted s

    e- e (W 990: 6) e pex pe

    (25).

    I h , I e ivF h pex x p-

    . M e e ivF ehz -

    oloy, or as a bolocal technoloy, but as a case stuy that asks us to conser

    e eph h h p eh , ex. The he

    h h ivF e eh h

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    FiurE intro.. S Jh Tee Ae , pe:

    The he e , e h h e ee he

    qe ee, h he e ee

    pe. e, he pe he ex he e eee e e.

    Le C, Through the Looking Glass (87).

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    6 introduction

    h h ee -

    e h eh ee, e he e e-

    hp eee he. The e he h h he e

    e h ivF h e e e , ee

    hh ee, e ee h - . A h , e pehp e ee e

    p qe he e ehp eee

    eh e pe eee epe eh he

    e hp.

    W p e he qe h ivF h ee e

    e, e ze ze, e e ee q

    or ordnry. To ben wth, ivF s tehnqe tht repltes well- known

    pe, e ez, he eh pe eh. I h epe: e e-

    pe ep, epe e h -

    rms, or proes, tht t works tehnololly. Representtons o ivF typ-

    epe, ee, e he e

    reroucton an the unersal esre or arenthoo to the alue o scentc

    pe he ee e e he e ivF

    turn oere as roo, or eence, o how these locs t toether. As oucault

    h he ee, ivF ee e e ehqe z, he, he e, hp, e-

    der, sent proress, expermentl embryoloy, lestok breedn, bby

    he, e e, e eh, e H-

    wood nem, Sex and the City, Brneln, nd Mmsnet.om. Bt s o-

    h he e, h h e ivF he ee

    epe p he ee h e ee

    .

    P he ivF epe hp pe,

    the lo o whh ivF reptltes extly n ts emphss on the bolo-

    ez ee . Hee, h e e

    exsts n two orms as a result o ivFthe one occurrn n o, an the other

    . I ez h e eh ep e

    e , ee, e pe p e

    ex ep h e e ee

    . The z ivF, Ch Thp p , h-

    (2005: 5) h e eh ee h ex-

    ex, ee, hp , eee fex he e-

    p ep, he e eep he e e,

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    rElativEly bioloical 7

    hp . Ye ee h ee, he

    ee he e epe, he e

    heee, h h ep ex, he, I -

    hee, .

    The e hh ivF eee , ee eee ,the normlzn systems t both reles pon or ts sess nd reprodes

    hh , pee hee e ee he e e

    ivF. Indeed, these two sdes o ivFhow t s both norml nd nothelp

    to expln why the experene o nderon t remns so prdoxl nd

    mblent, despte the pprent obosness o why ivF me nto ben

    to ben wth. The more pelr spets o ivF ery qkly beome ob-

    e e ivF p, ee h e

    I eee ivF ee he ee -mt world o ivF tretment (rnkln 1997: 11). One nsde ths topsy-

    try world, ery derent lo o ivF beomes sble, whh s nether

    e-ee h e he he e he

    nto the sssted onepton ln. Here, s or Ale, nothn s norml t

    ll. In tro ertlzton s not smple proess o steps ledn to poten-

    e e je epe,

    je e, e, pee, e j,

    e h. Y he eee ee ee hh p , he e hh eh ehe e p e-

    ment re onstntly hnn. As n the ontext o mnoentess, nother

    hh-eh epe ee, hee ee e e pe,

    he expeee ivF e. I pex e

    pee h eqe hh ee pe e, e

    s tme nd resores. Een people who seed n the eort to hee

    e-he e e e ee he he expeee

    e ivF. Se h he ee epe e h,

    he he ehe ee e p (Th

    2004). ew people o throh ivF, n other words, wthot experenn,

    ether temporrly or permnently, nd to reter or lesser extent, de-

    ee ee h pee e h e he

    ivF e, h ee h e he pe hh

    ivF. Th ee exe he eee eee he h

    ivF e , he exe hh hee hee

    e e e.

    The mblene tht hrterzes the ivF enonter, whle spe n

    ivF ee, e ee, I ee hh

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    8 introduction

    ths book as technolocal ambalence, arun that t s a consttute com-

    pe e. A he he e, h

    Uh Be (992), ee e he e he he

    modern reltonshp to tehnoloybe t teleson or e- ml, robots or

    botehnoloy, eletr kettles or plst bs. In tro ertlzton oers useul ersecte on ths ambalence because t s enerate out o a context

    h, e ivF e, e h e ee h -

    e eh he ex e e.

    Th h ivF pe e e he e I e

    eee ivF p, p-

    p h ep ee. The p-

    ivF, h -- pex, pe-

    e , h e - , e e e e, pe he e e-

    pe e. The e e h e ivF h

    h e h e h e e heee-

    pp e he e .

    Hee, I e h he ee p e h

    the tehnqe o ivF, whle derte n prt o ts role s modern, syn-

    thet, hh-teh proedre, lso reerenes older qestons o sex, ender,

    hphh ivF hep ppee e exp. I he, ivF e pepee he ee e h

    e eh, h h ee Be, e e

    , e hp. The h he z

    ivF h he he ee e h e -

    e eh heeee h

    hee e epe ehe h eee eep

    ee. A Mhe Peez e h h ee

    (the smltneos experene o powerl, ontrdtory emotons or tt-

    e e phee, he ee ), hp he

    deoted snt ttenton not only to the myrd sores o mblene bt

    lso to ther mpltons or n nderstndn o strtre nd eny s

    well as crtcally mortant rocesses o socalty, omnaton, an resstance

    (200: 44). Th e p Peez hee exe ee

    such as a ont o requently oerlooke contnuty between the ol an new

    hp e (200: 44) he ex e e ivF.

    Th h h ep ee ee ee

    thnkn about boloy an technoloy nto a conersaton about ivF that may

    e ppe he je. A e e, e-

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    rElativEly bioloical 9

    he ivF eh, pex -

    p, e, he h ee

    pee, e e, e eeqe

    h hh he e. Th e he

    eheh ehe hp e eqpe, ehe ex e he e he Iee. S, h

    e h h eh e, e h e

    he ee ee. Thee h

    h pje e e, h h e

    e pph hee qe. Hee, e e-

    e e he eze e pe, he

    eee he e e pe ee

    onerston, not only bot ivF bt bot the qeston onernn teh-noloy nd ts new knshp wth the qeston onernn boloy. These

    qe e e he ee eh, he -

    ee h pe z.

    Ths s a conersaton that has alreay been ery substantally eeloe n

    e e he, expe he hp ee

    ehe hp, he e ee ehe e-

    e, e he epe ex eh. I

    e he exe hh Mx e e eh- ee e h e , he

    he e eee h . Th ep e-

    heze ep, e epe eh, I he e

    pee e ee h hee p, e e

    ee e, p he D H (976,

    997). Re he he e h I expe pe

    , Dolly Mixtures ( 2007), I ep exe he

    e pee he ex expee e, -

    h he e pee eepe R Rpp (999)

    he ex ep epe ee. I expe he -

    ee he e pe , f,

    he e he e he phphe

    eee he e ep (acu) hee I he e he

    p e e, e he qe e eh

    h I e ivF pe eq e.

    A pe , h ee e h e-

    tsts nd lnns workn n the elds o ivF, stem ell reserh, nd re-

    enerte medne, s well s ptents nderon ros proedres,

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    0 introduction

    or te n ptent spport rops. Althoh ths book s not trdtonlly

    ehph, e , he expee

    scentsts who took the tme to ntrouce me to ther techncal workn meth-

    . The I e he e ivF, h e e

    ell derton methods, nd mromnplton o embryos hs beneted he e ee h hh pe e e ex-

    he hhe e e. I , h h he

    he , e expe hh I he e

    h , p e he pee ehqe

    p h e e e.

    As reslt o ts own somewht eentr pssn tehnqes, ths

    pe ee e eee hpe h ep

    to make sense o the socal, cultural, an technolocal leaces o ivF throuh ee epee e h h ep ee. Thh, I

    ze ivF e h e e e e, e

    hh hh ep he he e , eh,

    hp. T h I ze epe e eh,

    eh epe e, e he e he

    he eh h e ze , hh, ivF.

    The x ehe hee pepee h e he

    eh ee e ppe eepe eanalyss than a thouht exerment n the orm o a mosac. The am s to char-

    eze he e e ivF.

    Th e e ( e) p ee

    j qe h h e h ivF h ee e-

    tooln o hmn reprodte sbstne. Ordnrly, tehnoloy mht be

    e eh h e e hee ee e:

    tratonally ene as the alcaton o scence. Howeer, many o the most

    fe he eh he e h eh eqpe

    nd eny re orm o nhertnendeed o nherted sbstnes

    h e e he h exee he pee

    he e. Th , hh ee, he e

    knsh theory that nsttutons such as monarches are technoloesnee

    epe ehee he e p h -

    e e e he e e. The ee eh-

    eqehe he p e e e e h

    e he e ep ehe pe e h

    ep he ph he e h e

    e ee, , epe ee. I e e he eh-

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    rElativEly bioloical

    noloes o rltre or domestton, or exmple, not to menton ele-

    ( h e he ), e ee h he

    e e h p h e e h e e ee e

    them, ther perse strtrn eets s nsble s rmmr (lne

    e he p h ehe). Heege, expe, The Question Concerning Technology, epe he Gee e-

    he techne exp e: I e-

    e, , h techne -h (993: 39).

    S, B, De, Th, Heege e h

    ehe e he e hh he ee ee

    h, hp he he Be exee (993: 350).

    Th eqpe, h hh e e, h hee e,

    hp h h e he . Jqe De (974), - he peeh A Le-Gh, e ee

    mn or nthropos s rooted n n ornry tehnty poston re-

    ently nterpreted by Vk Krby (2011) s one tht mht lso llow or

    e e e eh. B L (993) h ee e-

    e j, h, ee ee.

    Or, s Donn Hrwy pts t more dly, hmers o hmns nd non-

    hmns, mhnes nd ornsms, sbjets nd objets, re the obltory

    pe p, he ee , hh hh ee p e h hee he (997: 43). We ee

    e ehe ee h eh e. H e he

    ee h eh h qe:

    Wllms (1990) so wsely noted, t s the ery obosness o ths qeston

    h e ze.

    As well s rermn tehnoloy, ths book lso seeks to rerme some

    o the rments onernn tehnolol reprodton rom wthn the

    h he. expe, h he ee hh, I e

    t s possble to red Mrxs onts o mhnes nd tehnoloy s more

    morphoenet thn perhps een he ntended. Mrx repetedly red

    h he e eh e e he eee

    e e e h Je W, he e ehe

    on eery lhtblb or the eponymos enery sore by whh yo my be

    rean ths book. Althouh Marxs enorsement o the alue o moern tech-

    e ppe Heege e h ehz e-

    e, he he e h Mx h eh -

    he p h, e pe. The eqpe

    he I Re, he e, e e e p

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    2 introduction

    e , he he . He e he e-

    ton o machnes such as the sel-actn mule jenny n the context o the socal

    pp h pe he he p, h he

    exee, h he he ehz -

    e. I h Mx e , he eqpe e -e h e hee h ex-

    ee, e he h pee e.

    A Mx e Ve Capital, he h e p

    h e he pe: L , he pe, p-

    e hh h Ne ppe, hh h

    , ee, he e e- eee he

    Ne. He ppe he Ne e he e, e

    n moton rms nd le, hed nd hnds, the ntrl ores o hs body, norer to arorate Natures rouctons n a orm aate to hs own wants.

    By ths tn on the externl world nd hnn t, he t the sme tme

    he h e (mEcw, V. 35, Capital, V. , B , C 7, e ).

    Mx e he h h eh he

    e h pepe e he e h, h he

    pe heee he ph p ee -

    ormed by them. He lso emphszed the solty o bodesther rl

    ee h he e, h e. Bh nd tools were nderstood s rl omponents o systemt mode o

    p h , he e p, hh ze,

    nd een to ertn extent symbot (e.., loer = ntroen = odder =

    cattle = roletarat = surlus alue = commoty = nance, etc.). As ths book

    ge, Mx e he h--he e -

    . H pe h hh pe substantial-

    ization hh hh he h e he hee, e

    ( , Heege he ) eqpe

    hstorl moment bt by ben ontnlly reondtoned by the eolton

    h eqpe, h , expe, he e p

    e eh p. H ep he e

    o mhne tehnoloy s deeply nsed wth the oneptl pprts o

    eepe h ee e pe

    h ee.

    The e eh eqpe peee Mx

    e e he h eh. Th peppe e

    , ee Be See (998) e

    Mx e he e h eh. The e he

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    rElativEly bioloical 3

    h h , e eh e, h

    prodton, s entrl to Mrxs dletl theory o mhnes nd meh-

    nzton, oten nokn Drwns model o ntrl hstory (despte Mrxs

    nd Enelss rtqes o Drwn s n polost or ndstrl ptlsm,

    he e h e ee p ee eh-). S, Mx e epe he ph

    as a tool kt mae aalable or human use, an transorme by these uses nto

    e e (Sh OKeee 980). T h , Mx e he

    e, e, e ehe hh hh he e

    p ze e. Thee , he e, pe he

    ee ee eh ee he he

    p eep, , epe e.

    h p e, he e e, dee, tht s en prpose by ts ser s not lly deqtebese, s

    both Marx an Enels arue, the sncance o tools cannot be measure by

    he e. T, he e eh, e e-

    h hee eqpe he h

    exee, ehp h he h h , -

    e pe h exe e h e he h

    pee eeee. Me h h, e ee ee e:

    Heege e, he e he h hh, Mx red, tools re the osprn o mned worlds s mh s tl ones.

    T e ze ep.

    As Donn Hrwy (1997: 52) hs red, the ontext o ontemporry

    eh p e h ee ,

    ep, e he , e

    hh e e peze h e e

    nto technque an an mloson o materal an semotc technoloes as new

    hp . The e e e, he e, he p

    ee h p h h eh-

    e hehe e he ee e

    e, , h, , he (H 997:

    99). The e e e e ee, he, e

    . . . p he h he (3536), h

    p he e h e hpepee h

    ts transhybrtes (134). To the extent that molecular boloy s remse on

    he pe e , ee e ee he

    uture o bolocal knsh as a set o relatonshs not only to, an throuh,

    , eh.

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    4 introduction

    Th e qe, hh h ee he

    e he h h e ep-

    e e, . A qe e he p e

    ivF eh e he p h e, p e e-

    e h e e eeh, h e e ep-e e eh, eh epe e,

    e e ee e e e e h,

    e he . A e e p e pepe

    e h qe ehe Mx Heege, he he

    eh, h he pe hee ee z-

    ehe ep epe e. Iee e e

    ee e e ep ee he h ep .

    Conentonally, reroucton has been unerstoo n two stnct sensesas a rocess o socal relacement (as n the reroucton o labor ower), an

    s bolol proess (s n sexl reprodton). Somewht onsnly,

    ep e e ee ee p.

    Ths s the exact ooste o what t has meant n the context o boloy, where

    ex ep pee he e h p, ex e-

    p, . Th pe he,

    an also by a eneral nelect o the mortance o what Marx calle the moe

    o reprodton or the sexl dson o lbor. Indeed, throhot Mrxs he e e e e expe he e. Hee,

    he e eeh e h ee e ee h

    ex ep pe h e ehpe

    eh (hh h he phe ep e),

    h e e eh (e.., pe e e , h

    e ). Wh ivF e p e eh-

    local transer, or assan, by whch the technolozaton o bolocal sub-

    e ee e ep ( e )

    ex , h, , , , eh-

    ep. P , he e ep-

    e he j eh e he eeh

    e, e e h h ee e e heze (p-

    he H). I ez he e hh h

    e eh h ee ee he h, h

    e e eh pe e e

    eh e.

    One o the most helpl models or ddressn the ontemporry en-

    ee e (P 987), he pe e (L-

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    rElativEly bioloical 5

    deker 2007), s tht desrbed n Adele Clrkes (1998) ont o ds-

    plnn reprodton. As Clrke notes, the reprodte senes he

    heee ee ze, he e he e pje

    e h hee ee pe e, epe he ,

    he he p , h he epe ee hhe e e e ep e

    heredty, nd hene oer le tsel (1998: 276). The ontrol o reprod-

    e e hh ehe eee ee , e ,

    e he e e h ee he p,

    expe, e e e. D he eeeh e, e -

    eh eee ee e e e e h

    Re Bee, h e pe he epe e

    h e e ee he e e, eh h -- ee e ee x ee

    pe h ee, He R (987) h h, e -

    drdzn nmls, s well s new mens o lltn ther tness, do-

    e he epe pee, e e -

    e e he ee p. Lee ee e, e

    -ex Bee ee (h he Dhe Leee heep) e

    ths nstrmentl ley (nd he themseles now beome lble om-

    modtes). Selete breedn, whh sbstntlzes onept n the orm ehqe ppe ep (.e., -- e ee

    to onentrte desrble trts), reles on son o boloy nd tehnqe

    hee he p ep (Ce 998). The e

    ppe ppe he e ee e eeee,

    hee h epe ep e e eee, exe,

    ee.

    A ee eh ee he eeeh e ee

    he z h epe e he p

    epe ee, he ep hp. I he D-

    , h G Bee (983) M She (992) he h,

    he hp pee p he -

    eh peee h e he

    he eee e hh he eeh ,

    hh he epe e. I h e e,

    e, h e e e, e, qe

    ep e e he e e pe -

    ( 973). Oe ee e e, e,

    e e e e pp p

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    6 introduction

    , h he he pee ee h -

    ee pe. Th he e epe e h e

    h h ivFj e e e D ee

    h ( hp) e eee, eph, e-

    (e). Le D e e, ivF e e- e ee: e e ee, e

    e e eee. Th ee ivF e

    he hee hh h e ee epe e p-

    e I ee e, hh hh ex

    e exp e, ee, . Oe he

    ee ivF h q hh he exp ehz

    reprodte sbstne t mkes so rphlly sble, nd the rdl new

    e e e, he ee ze -eze.

    One reson or the rpd dopton o ivF tehnoloy s, o orse, tht

    e e. A B L e, he pe

    e he eee he ppe h e

    . H ee , he e, h pe e-

    ee, Ne e ze, hze, ze (L 993:

    37). The e e ee , hp, he ep-

    te substanceall o whch are characterze by enormous fexblty n ste e e e ee e. A Je Ce h e, he

    term sbstne hs n enormos nd red rne o menns, oern

    hee pe he Oxford English Dictionary. She ee hee

    brod teores: tl prt or essene; seprte dstnt thn; tht whh

    ee phee; pe e (Ce 200: 29). Whe

    the one hnd, Crsten srmses, the hhly red menns o sbstne

    my be one o the resons t s ood to thnk wth, ths bredth hs lso

    e . expe, e e e

    e ph e. Th e he

    sbstnes tht does not perse throh the plentl membrne, nd n

    h ee ee he, h he epe e

    eee. B h e e? T-

    tonally, an n a Euro-Amercan context, these woul be escrbe as knsh

    e h e ee e h he e h he

    e he , , e (Shee 968). A

    Crsten notes, howeer, sh denton both onses nd onftes two

    ery derent menns o sbstnes symbol nd essene. Ths onf-

    ee M D ep -

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    rElativEly bioloical 7

    , e e hh he e he e e-

    e efe ehe eh pe expeee e (970:

    0). A e ee pepee e Aee M

    (2002), h e e epze h e h

    sbstne derent menns n terms o how t s done throh rosehqe expe, he ex ee. I he e, e

    e e pe e pe e: ehe

    ee e eeze , he e exee

    epe h ee e pe eh

    e.

    he ppe h , z e h he e

    h ee ph, ee e, hp, hee

    ep h ee, ez, z, ez he ee epe ee he ehp eee

    ee, , e, e je, eh. I he -

    ex hee ee e h he eh e he

    word sbstne selly both expresses nd onrms. At the sme tme,

    ths term s lso sel or ths book bese t hs mh more spe

    e he ex ep, hee he e epe -

    e ee ee e. A, e he

    p ep he h pe e ep-e e h h ee ee he eepe

    eh e he eeee pe e. A

    he PS e e ee , eee ep e

    e e he ex e e ee (hh h

    he D expee e). Th e ivF, hh

    be seen s n eoln tehnolol pltorm, sern s bse or n ex-

    p e h e eh, hh e e

    he ppe pe h e epee ep. H

    e e e eeh e p he e he ivF

    p: ee he e eeh e ee-

    pe h ee ivF e e h, epee h

    ivF or the suly o research embryos necessary to the renement o ts cln-

    pp.

    Both the chane n the meann o reroucte substance brouht about

    hh e e eeh ( h ee e ee ee)

    he e e e pe pp e

    e ivF pex . Mh eeh pee h

    e e ee U.K. e h he ee ee,

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    8 introduction

    , eeee e e ee ee eee

    ivF nd stem ell reserh. The xs o these lbs, both rhtetrlly nd

    ep, he he , hh, e he je

    acu. The e e epe eee e

    can thus be more relably, or cleanly, acltate rom one context to another,h , ivF e e ( h; ee

    2010b). Ths book bens nd ends n the ledn U.K. lb dedted to the

    h e e epe e, G Hp

    L, hee he ivFe e ee e e he

    he qe h hp e e e eeee he ex

    e epe ehe.

    The e e ivF e e eeh ze

    h e e e ivF he hee hh he h h e he he he . O e e

    e pe e acu e pee, ivF. Thee

    pe e ee pe epe e, -

    p he peee acu e he ,

    he e, pe he h he

    e ep. I he e he exe

    e expe ee h, ivF p epe

    ee he he. I ez ex e he-e, e pp ee , e eeh

    prorms, lel nstrments, brert proedres, tehnl sklls, nd

    ethl odes (nd so on). Now n expndn lobl sere setor, the ivF

    h ee eee x e ehe, pe-

    e, p, e. Th x he e e -

    e ee h exee he e ex ep

    e, h he h e p exe e

    , eh, hp.

    Thee e e p e h e e eepe hh

    the hole n the wll (re Intro.2), lnkn the stem ell lb to the acu,

    throuh a comlex seres o embryo transers (rankln 2006a, 2006b, 2006c,

    2008, 200; Kz 2008). I he , eh - ,

    he pex ee e e epe e h

    e pe ee eeh e h e ep

    e e e ee e pp, h e eee,

    reenerte medne, nd dnosts. Here, the sophstted hndwork

    p-h e e e e e e -

    e e e e e, e epe ee

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    rElativEly bioloical 9

    p e p h e e p -

    . S, he UK Se Ce B, hh he h e-

    e e eehe, he ee -

    ton, store, trnsport, hndln, nd bnkn o hmn embryon stem

    e e e ee, h he e pe e he e eh ( e . 2008; K 2009). Thee

    new stndrds omprse the most elborte qlty mnement protools

    ee e epe e. The e he eqe he -

    ep ee Geeh Me Te.

    The he he h e e e ep-

    , pehp - (e I.3). Thh , h ep-

    e e e he h ee ivF e

    become a tool that s embee n a new set o coes or conuct. These coes pe e h hppe e, he ehp

    h e ehe hh he, h eh e e e

    he exhe epe e. Th e e e e

    h e-e ee p he eqpe e

    epe e e ee ee p-

    eh , ee ppe e e e ee e

    e e hepe ppe. I h hee, he e-

    e e e, h he e e, ee ee, e peze, h e-

    p x h he je h .

    tcs f Sx

    A ee he e e he e he h e-

    he eeh-e e, e he ex

    eh. The phe ehe ex e Mhe -

    e e he e e h ivF peee he 970.

    Lke Mrx, howeer, olt sed reltely nrrow model o reprod-

    h hh fe h he h he h ee

    he h pe hh he ehz ex. H p-

    e e e h e eh, p

    hh h he ehp eee ee pe

    eh e. A he pe , he e ex h hh he

    ee pe e e ze h

    e epe ph ( 990: 5455).1

    The e ehe ex e h ep-

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    20 introduction

    epe eh pe e e h e

    sholrshp n the 1980s. Bldn both on Mrxst pprohes nd on the

    work o erler emnsts, sh s Smone de Beor, Rth Hershberer,

    Shh ee, he phe ehe ex e e-

    , p hh he Tee e Le (987) Jh

    Be (990). Ne e ex, ee, ep e eee

    h e hp, e Ge R (975) ep

    he ex/ee e h Shh ee (972) ee he h

    e he p e ex. The qe he ee

    ee epe he ze, p pe-

    smpton o n tomt sexl bse to hmn sol rrnements s

    e he e ee expe.

    Anthroolosts such as Marlyn Strathern were amon the rst to ben to

    aly these nshts seccally to ivF. Somewhat roncally, Strathern (1992a,

    992) pe , ivF exp ze he e e h ee

    ormerly mane to roun the natural orns o ener an sex: these acts

    FiurE intro.2. The he he eee he ivF he e e

    ee he pe, e, eg e h

    eee ex e e. Ph he h, phe h

    pe he G e e e.

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    rElativEly bioloical 2

    ee eee e, eze, he e eh eepe

    he. B ep ep, ivF e ee e

    eh ex ex pe he e e h

    ehe ex ee h pe he ee ze -

    , he h . he e e, he e e ep

    ehqe he epe e eh

    pe e ee eee

    e e, hh hh e e e-

    me nterhneble. Intended to enble ople to reprode bolol

    p, ivF px eze ep

    , h. The ez hee ehqe -

    ze he e p h eee eg

    sperm, bt tht between tehnoloy nd boloy. Ths end opln hs

    q ee e he e--e eh e-

    ee h ee he e h e he .

    Th h ivF e e e e e

    FiurE intro.3. A e he ivF ee hee he e he Ae

    Cep C, Pe Pee Be, exp he h eg e

    ivF e e . Ph he h, phe h

    pe he G e e e.

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    22 introduction

    e e. I , he e ee p, e, h

    p e h e he ppe

    o uture knshs not only between arent an chl, but between technoloy

    p. The e ehp eee ivF he e ex

    eh hh p h pe eqe he e h eh, e he

    ehp h e ehe ee, ep,

    ex hh he ee eh e .

    The p exp ivF e ee

    eh p, e he eh ,

    h ee h e he p ee qe e-

    e he e h . , h h e h e-

    pe e eh, eh epe -e? A e, h hee ee qe e ze ehe?

    A e e, he eh h expee. Bio-

    logical Relatives ze ee e e ex expe

    e ee pepee he qe e e ivF. I e

    ee hpe h , pex e. Re ee

    pe, I he ee eh h ee he eeee

    eh he ex ivF, I e ivF h e

    e h pe. I h he e ivF h e e e h he he he hh expee h

    ehh e hh pee he h e.

    A e h eh h eh hpe e ee

    e he e he h eee he ee -

    . Whe h e , p e h e.

    Mh s let to the reder to ner ross the hpters, whh toether t-

    ep e e x h e ehe

    he. Ohe he pe h e hee he ivF,

    R Mz He (2004) Pandoras Baby, Re

    P Sepe (980)A Matter of Life. S, hee e h ee

    h epe , Aee Ce (998)

    Disciplining Reproduction Je Mehe (2003) Whose View of Life?

    Nehe ep p ivF pe hee hpe, h

    h e De Sp (2006) The Baby Business,

    ebate the ethcal mlcatons o new reroucte an enetc technoloes,

    h ee e Je He (2003), (2002),

    he. I he h h e h e

    ee h e hh eee pph ee he p e

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    24 introduction

    red nd re-presented n order to deelop the nlyss rther. The emph-

    ss on lose redns o key texts throhot ths book s lso reprod-

    e eh , e he pee h ep ee

    n ext proess, nd tht repetton s tsel enerte mehnsm. The

    pe hh expee h h pje efee h , hh e e ee e h ( ee

    ntrdtonl) ethnorph monorph. As noted n the terword, sb-

    hee he eee e ee pe ee

    e-p peee h he e peee hee, he ee

    h e e.

    Chpe , Me Be, exe ivF h ee

    ep, e epe e h. I ee,

    he h, he eeee he ivFe e ee he o a new eneraton o urose-bult labs n the Unte Knom, an the ub-

    pe ee h h pe he e

    enerton o embryon tools, most reently hmn-dmxed embryos,

    lelzed n 2010. In ddton, ths hpter explores the ondton o ben

    e ivF ep heze h h ee ee. The

    eeee he ivF he pe e ee I

    Re, e he he , e h ee-

    h Mx h he e e.Chpter 2, Ln Tools, rermes the oerll projet o Biological Rela-

    tives he D H Shh ee,

    e e he e e e e h exe

    ivF . Hee e ee e e ee e p e

    e q- e ehze ze

    e ep. We e hh he he he ,

    ivF eg he e e h ee ehe pe p

    h . D Mx he, h hp-

    e h eep he hee e e hpe e

    e ep e exep he ee pe e exe

    h .

    Chpter 3, Embryo Poneers, ontns n epsod tor o some o the

    e ee he h expee e h I ge

    e hep ppe he ee ehqe h e

    hmn ivFnd to nderstndn the eort to mehnze reprodte

    e, p . I exe he eph eh-

    qe h e hpe 2, pe e eh he

    h h ivF. The h hpe expe he e

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    rElativEly bioloical 25

    use o embryo transer, artcal ertlzaton, an tssue culture n the makn

    o what has come to be known as the reroucte ronter an to urther ex-

    pe h e. A e, hpe 3 e e he

    o the ronter dom n the ontext o boloy s tehnoloy ( theme tht

    eepe he hpe 7). D he h hhe ee h p e e h I he, Hh

    Lee, S Ge, N Hp, I e he h

    h ivF e he eh expee e h

    peee , e h exee pe e-

    e h ee ee ee he pe

    hh h .

    Chpe 4, Repe Tehe, he h

    ex he ex expee e eepe h he ex eh ex ee ehe he e

    e heze h e ee he 980, p h

    e hp. Th hpe e e e he h

    Gyle Rbn nd Mrlyn Strthern, whle lso reredn the emerene o

    e ee eh. The ehe h e- e

    rond s mehnl omprson between the tehnoloes o knshp,

    ee, ex, he e hpe 3 exee h e

    he , ee, pe e he e efe h ivF . Hee, eehee, he e ee ee

    work on knshp nd ender n the lht o ben seerl dedes ter the

    h he e-e , ephze h he ivF h

    e he e ee hph pe

    e h ee he e e.

    Chpe 5, L ivF, e e h, e he

    e ee e e epe ehe he 980. A, h

    he ee exee h h h -

    e, h ee pe qe , e he

    nderstndn the experene o women nderon ivFrbly one o

    he ee ep e h epe eh-

    noloy, nd o sssted onepton s mens o don ender s well s

    hp. I e h he e e e expe-

    ee ivF eee e expe ee ephp e

    many o the ways n whch ambalent relatonshs to bolocal technoloes

    he been theorzed sne the 1980s. Ths hpter more expltly enes

    h he hh he ivF pe e -

    counts o ener an sex as technoloesan nee as reroucte tech-

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    26 introduction

    e. I e ivF eh e,

    eh h e e, h h pe

    e h e e h he

    ppe.

    Imortantly, ths arument has alreay been mae ery eleantly by CharsThp (2005) he p ivF eh ee, p

    ttleMaking Parents. Drawn on Thomsons work n chater 6 (ivF Le),

    I expe he qe h ivF ep , e

    e , p. Th hpe pe he he qe-

    h ivF e. H h ee h pp eh

    e e, h e ivF? T expe hee

    qe eh ee , I he e h hpe 6

    he e ivF eh , eh h ee e e exp e eh-

    nolocal substance as boloy. In orer to unerstan not only the loc o ivF

    eh, ee he e ivF

    eh pe he e e, e he

    he e epe e , p, ee,

    e, e h e pp ee

    p (ee) ee e.

    Th e he ehph e hee e. Chpe 7, -e Ce, e he he he , h e h he acu,

    ppe he , hee he Bh G Ge h he he e

    ivF phphe eee. L hh Ge e e-

    bles the qeston o ivF s wy o le to be expnded nto broder

    qe h eh pe, ee, ze.

    Hee, he qe he e expe e exp he

    e hp, he e hp expe he p e

    o how technoloy tsel has become a orm o share reroucte substance.

    Th qe e ee h hpe hh e

    eh pe e, ivF e h e

    ee pe. L e he h -

    e h h peee eeee , he qe e e ivF

    explored both slly nd experentlly s ste o rerted dentty nd

    e .

    The e hee he e ef ze he e

    by reredn Derrds nderstndn o the reltonshp between tehns

    e hh he e ivF. D he Hh Ae,

    the qeston onernn tehnoloy s here posed s one o dloe: wht

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    rElativEly bioloical 27

    e he e e h he he e eh

    s boloy, or the tre o boloy s tehnoloyor the tre o knshp

    e h hee qe? B ee he e

    Biological Relatives h e, I e he e h he h

    ep p he e epe e he ex ivFpe p he e p-

    e e e. Wh ee e ee he e e

    ee e he e? Mh ivF e ex hh h

    e eh e pe expe?

    B he eh h e he

    necessary recontons or a human embryo to become a tool, my oerall am

    e ivF h exe ee e hh-

    h he qe pe he e ee, ee, botechnoloy. As set out n ths ntroucton, the am s to roe a erent

    set o strtn ponts or ddressn the relton between the tehnolol

    he e h e he e e. I p, he

    hee he e eh p h pee

    h He (97: 58) h ee he e

    eh pe. B ep e e hp e-

    e he expe h e e e ivF, Biological Relatives p-

    e ivF e e eeh h e pph heephenomen s embedded n sol ontext, or een s molded or shped

    e. A e ee he phe ee

    socety or the socal consequences o technoloy, an mlct searaton be-

    ee he he he e eh

    . Ye h ep e e: ee eh-

    e ee e he , j ivF e e, e

    e e ex ee he ee e e exee.

    O he e h h pe ee -

    e, e, , ex ph-

    lol perspetes on ivF, one o the most promnent s the dlty o

    e he e eh h ep ex ee

    s embryoloy, nthropoloy, hstororphy, emnst theory, ontnentl

    phlosophy, or bopolts. Ths problem s omponded by the qeston o

    wht s ment by tehnolol. Hene, or exmple, we mht desrbe

    e he Iee eh, e e e e h

    ee eppe, h e e, , -

    e p. Hee, e hh, e ee h hee

    orms re thorohly tehnololthey depend on pror tehnty, nd

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    28 introduction

    we ene them throh omplex tehnqes tht nlde not only know-

    h e h e e, h e , h e

    e. Khp, , e, e p, h e,

    h e e he e hh e pe

    eh e, h e, , , h he eeeepe pe e. Iee, hee e e he e

    h ehe, e e e he ehe h e

    h.

    I h e e h p e h eeh eh-

    l. And t s worth skn wht or denton o hmnty wold be t

    were dentrlzed n ths wy. or one thn, sh thoht experment

    eqe h e ee h e e pee h e e

    he e e he eh, ehqe, p -e he e h, pe ex, e e, he

    eep, he, , ee ex, exp. Techne he Gee e

    , hee eh e e e ee eh

    e. Tehqe e ee e pe, hee eh

    e e ehe h he pp ee, h e

    mehnl tehnqes, s n the ontext o ndstrlzton. Whle we do

    not onentonlly ssote tehnoloy wth ender dentty or mrre,

    these too are, o course, hhly oranze acttes that rely on ror art. Tech- ee he Gee tekhnologiae ee

    he , h ee pe.

    hp p e, h e pe eh-

    , ehqe, ehe e ee e eh-

    h .

    Oe e, hee, h e epe e

    eh h ee he pp ee h

    tomt reton to the ntrl ts o reprodte boloy, n essene

    ee z he e, , . I ez-

    e e h expe h e

    an embryo to become a bolocal tool, or or our unerstann o technoloy

    to become more bolocal, but or these two ersectes to be combne n

    he hh expee hh hh e h

    eh e h eepee ee. I e h ivF

    ee e he eh epe e-

    e ee, h h h e e he jee -

    lol. Throh ivF tehnoloy, reprodton beomes reltely bolo-

    ee, he e hee hh he ehqe

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    rElativEly bioloical 29

    ivF e: e e e , epe,

    e e h. The ivF e pee he e eh-

    ze e, he h pe h ee ee he

    hp epee he e ze, e,

    an actate human rerouctty, an also commonly resume to be one ohe e eee h ehe. S he ee, hee

    two tehnoloesivF nd knshpre lredy bololly relted. They

    he he e ee he e ppe: he e e

    tehnoloes n the mkn o kn nd the kndn o le. The pont o ths

    expe h ee h ivF e hh exp,

    h ee pe ppe e ,

    eze , e exep e

    ze exee. Thee pxe e h e ivF h h hp. The pje h j h. I

    e, ehe eh qe he e

    e e he eexe he hh he ivF, he -

    e e e h pee.

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    noteS

    intRoduCtion

    1. The muue l ell deed, mg he hg, -

    e ee, eeg he mg ude ewee le d le, d

    l, ue d e. Shy Ymk eeed he bbva ud e

    Kwledge wd 2010 h eeg wk he mul ellul

    dfee hwy.

    2. The ed ue ivF, whh w glly deged exemel e-

    eh ehque ued e eeh edu d deelme,

    hum ll l geeed emu dee d med ege

    ely he 1940, d hughu he 1960 d 1970 (ee, e.g., dwd 1989). Hw-ee, R Mz Heg (2004: 173176) hle e he ew he

    h ehque lle, he y ivF he w dede llwg ue

    1978 e dl m m du ee g

    ll.

    3. Lke he l ly ee d ehlgy, I le hgh me

    hd- exeee he l, whee leg wh led u ehque

    d edue gely ee he ly ee hugh uh mehd, d-

    ued uhe he 2.

    4. du he mehd ued ue mmml emy, ee Rfey(1970: 5455), d he l u he me hee l deel-

    mel lgy, ee MLe (1976).

    5. Clke (1998: 276) ue he egle e he edue -

    ee h he dem d ul leue he mu eegy

    d e deed wd he Hum Geme Pje.

    6. The ew kd lgl ele dued y iv F lude, exmle,

    mull mee, dded gee d gel he, well

    ew ye lg, uh w ye d lg eed

    he Iee. Thee ew ye lgl ele he led hge he lw, d

    ewly exl de ehd, well mlex mdel lgl e-

    lede u ex ee d mede.

    7. Alhugh hee me dee u whehe PS ell wuld elme he eed

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    hum emy, ded eh emy m ivF gm em he gld -

    dd hum emy em ell eeh (ee uhe kl 2006, 2006,

    2007, 2008).

    8. I ue he em mx dee ivF h emhze me

    le ehlgl ee d eue mx ee u u-

    udg ue wh whh mehg ele ge, deel ed.

    The dy de mx l ee me ell ue d

    he wm. A mx uhe deed gud ue, dg ue

    (uh ee), d l mld dye. The em dee m L ee

    eedg ml mhe (American Heritage Dictionary). I meme l ee

    ivF lm ehlgy dee ue e gg u kd

    ehlgl delyme. Th mewh dfee m, lhugh mle

    wh, he e medl lm deeled y Pee Keg d Aled

    Cm dee de ee ehl e edue (Ke-

    g d Cm 2003: 3).

    9. uul ulhed La Volonte de Savoir, Vlume 1 h ee he hy

    exuly, 1976.

    10. Whe we me hee due hum exuly wh wh w kw

    he me u he hylgy ml d l edu, uul ee,

    we e uk y he guy. The eele e m he d eleme-

    y ly, me ey, e hem le he hy

    kwledge. They m gely muddled ze (1990: 54).

    one mracl Babs

    1. The eymlgl em he ue mee me le mee -

    lgy he Old eh mier, ue, m he L em merus. The ue -mee

    ux, lmee, dee m he eled L em meros, meg .

    I ee, lgl ely u whe mee he ee ly (meely -

    lgl) med me -mee he ee .

    2. A ul d ewee Cl d Bd e he lgy

    ehlgy gume lgy, d he h e ued dee ex gede

    ehlge, h he me e eekg ulze, he ee mlze,h ju, whee he le eek hee he eee efe, deulz-

    g hee me m.

    3. I h du he mlee mmy he ex lz,

    Hm Bhh ue he exe lm he me, u que he

    dule ul m, d he exe whh ule mlzed we

    d dly kwledge. I h mdel mlee, m due -

    l eee h e leel eg, u l meg, y dug -

    eg u he meh d meym xe he ulul du

    meg (Bhh 1984: 129130). I he ex ivF, he mlee mmy

    deeeed y he exe whh eglly ue he lgl edu-

    e well.