BIOLOGY 1-5-161ST ENTRY TASK FOR CHAPTER 12LEARNING OBJECTIVE: HOW DNA WAS DISCOVEREDSTRUCTURAL COMPONENTS OF DNAENTRY TASK: WHAT TYPE OF BIOLOGICAL MOLECULE IS DNA?WHERE IN THE CELL DNA IS FOUND?

TODAY’S PLAN

• DNA STRUCTURE NOTES• DNA STRUCTURE AND REPLICATION VIDEO (CRASH

COURSE)• HTTPS://WWW.YOUTUBE.COM/WATCH?V=8KK2ZWJRV0M

THINKING QUESTIONS

• HOW DO YOU THINK SCIENTISTS WERE ABLE TO DETERMINE THAT DNA WAS THE INHERITANCE MOLECULE THAT WAS PASSED FROM PARENTS TO OFFSPRING? (12.1)

HOMEWORK DUE TOMORROW

• READ SECTION 12.2 (PAGES 344-348), AND COMPLETE QUESTIONS FOR SECTION 12.2 IN WORKBOOK HANDED TODAY.

THE BASIC UNIT OF THE DNA MOLECULE IS CALLED:

NUCLEOTIDE

A NUCLEOTIDE IN DNA HAS THREE PARTS: A RING-SHAPED SUGAR CALLED DEOXYRIBOSE A PHOSPHATE GROUP A NITROGENOUS BASE (SINGLE OR DOUBLE RING OF

CARBON AND NITROGEN ATOMS)

Nucleotide monomers join together by covalent bonds between the sugar of one nucleotide and the phosphate of the next, forming a sugar-phosphate backbone.

NITROGENOUS BASES

THE BASES PAIR UP (A-T & G-C) FORMING THE DOUBLE HELIX FIRST DESCRIBED BY WATSON AND CRICK

EXIT TICKET

• WHAT ARE THE THREE MAIN PARTS OF A NUCLEOTIDE?• DO A DRAWING OF THE MOLECULE

BIOLOGY 1-6-162ND ENTRY TASK FOR CHAPTER 12LEARNING OBJECTIVE: STRUCTURAL COMPONENTS OF DNAWHY DNA NEEDS TO BE COPIED (REPLICATED)ENTRY TASK: WHAT IS THE SEQUENCE OF NITROGEN BASES THAT WOULD MATCH THIS: ATGACCTT WHAT DO THE LETTERS T, A, G, AND C STAND FOR?

TODAY’S PLAN

• DNA POGIL

WATSON AND CRICK FRANKLIN

Figured out the shape of the DNAmolecule

Used X-rays to take picturesOf DNA molecule

VARIOUS WAYS TO MODEL DNA STRUCTURE

•http://www.umass.edu/molvis/tutorials/dna/dnapairs.htm manipulate DNA

WHY DOES DNA NEED TO BE REPLICATED?

• TO REPLACE OLD CELLS• FOR GROWTH• REPRODUCTION (BACTERIA AND UNICELLULAR

ORGANISMS)

REPLICATION IN 3 STEPS DNA REPLICATION

RESULTS IN TWO NEW DNA MOLECULES, EACH CONTAINING ONE NEW STRAND (RED) AND ONE ORIGINAL STRAND (BLUE)

BIOLOGY 1-7-163RD ENTRY TASK FOR CHAPTER 12LEARNING OBJECTIVE: HOW DNA REPLICATES ENTRY TASK: WHAT DO YOU THINK IS THE FIRST THING THAT NEEDS TO HAPPEN TO THE DNA MOLECULE IN ORDER FOR IT TO BE COPIED?

TODAY’S PLAN

• DNA REPLICATION NOTES• DNA PAPER MODEL• DNA POGIL – FINISH REPLICATION SECTION

WATSON AND CRICK FRANKLIN

Figured out the shape of the DNAmolecule

Used X-rays to take picturesOf DNA molecule

VARIOUS WAYS TO MODEL DNA STRUCTURE

•http://www.umass.edu/molvis/tutorials/dna/dnapairs.htm manipulate DNA

WHY DOES DNA NEED TO BE REPLICATED?

• TO REPLACE OLD CELLS• FOR GROWTH• REPRODUCTION (BACTERIA AND UNICELLULAR

ORGANISMS)

REPLICATION IN 3 STEPS DNA REPLICATION

RESULTS IN TWO NEW DNA MOLECULES, EACH CONTAINING ONE NEW STRAND (RED) AND ONE ORIGINAL STRAND (BLUE)

BIG PICTURE OF DNA REPLICATION

REPLICATION REVIEW

DNA REPLICATION ANIMATIONS HTTP://WWW.YOUTUBE.COM/WATCH?V=4JTMOZAIVS0 HTTP://WWW.YOUTUBE.COM/WATCH?V=GW3QZF9CLIA HTTP://WWW.YOUTUBE.COM/WATCH?V=ONW_YKH3AVA HTTP://WWW.YOUTUBE.COM/WATCH?V=HC_8Y8FNKCW HTTPS://WWW.YOUTUBE.COM/WATCH?V=8KK2ZWJRV0M

CRASH COURSE

BIOLOGY 1-8-164TH ENTRY TASK FOR CHAPTER 12LEARNING OBJECTIVE: HOW DNA REPLICATESENTRY TASK: WHAT ARE THE TWO MAIN ENZYMES INVOLVED IN DNA REPLICATION? WHAT DO EACH OF THEM DO?GET A LAPTOP, WRITE CART AND LAPTOP NUMBER BY YOUR NAME ON SIGNUP CLIPBOARD) AND GET LAPTOP STARTED

TODAY’S PLAN

• DNA REPLICATION COMPUTER SIMULATION AND QUESTIONS

• HTTP://WWW.WILEY.COM/LEGACY/COLLEGE/BOYER/0470003790/ANIMATIONS/REPLICATION/REPLICATION.HTM

TED TALK – DNA REPLICATION – CHROMOSOMES- MALARIA• HTTP://WWW.YOUTUBE.COM/WATCH?V=DMPXU6GF18M• TIMING OF REPLICATION ARTICLE:• HTTP://

HMS.HARVARD.EDU/NEWS/MARCHING-OUR-OWN-SEQUENCES