biology - chapter 21
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biologyTRANSCRIPT
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Circulation and Respiration
Chapter 21
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21.1 Impacts/IssuesUp in Smoke
Smoking, a habit that usually begins in the teens, impairs the health of smokers and the people around them
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Video: Up in smoke
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21.2 Moving Substances Through a Body
All animals must supply their cells with nutrients and oxygen, and remove wastes
In some small invertebrates, materials simply diffuse through interstitial fluid
Interstitial fluid • Fluid between cells of a multicelled body
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Circulatory Systems
Complex animals distribute materials through a circulatory system, in which a heart pumps blood through blood vessels
Heart • Muscular organ that pumps fluid through a body
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Two Types of Circulatory Systems
Open circulatory system • Circulatory system in which blood leaves vessels
and flows among tissues
Closed circulatory system • Circulatory system in which blood stays inside a
continuous network of vessels• Flow is faster than in open systems• Found in all vertebrates and some invertebrates
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Closed Circulatory System
In a closed circulatory system, materials are transferred between blood and cells of other tissues by diffusion through capillaries
Capillaries • Smallest-diameter blood vessels; site of
exchanges of gases and other materials with tissues; a capillary bed supplies an organ
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Open and Closed Circulatory Systems
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Fig. 21-1a, p. 419
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Fig. 21-1a, p. 419
aorta heart
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Fig. 21-1b, p. 419
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Fig. 21-1b, p. 419
pump
spaces or cavities in body tissues
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Fig. 21-1c, p. 419
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Fig. 21-1c, p. 419
dorsal blood vessel
two of five hearts
ventral blood vessels
gut cavity
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Fig. 21-1d, p. 419
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Fig. 21-1d, p. 419
pump
large-diameter blood vessels (rapid flow)
large-diameter blood vessels (rapid flow)
capillary bed (many small vessels that serve as a diffusion zone)
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Animation: Types of circulatory systems
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Evolution of Vertebrate Cardiovascular Systems
Fishes have a two-chambered heart (atrium and ventricle), and blood flows in one circuit
Atrium • Heart chamber that receives blood from a vein
and pumps it into a ventricle
Ventricle • Heart chamber that pumps blood out of the heart
and into an artery
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Evolution of Vertebrate Cardiovascular Systems
In most vertebrates, blood flows in two circuits
Amphibians and most reptiles have a three-chambered heart with two atria and one ventricle
Crocodilians, birds, and mammals have a four-chambered heart that separates oxygen-rich blood from oxygen-poor blood
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Two Cardiovascular Circuits
Pulmonary circuit • Circuit through which blood flows from the heart
to the lungs and back
Systemic circuit • Circuit through which blood flows from the heart
to the body tissues and back
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Vertebrate Circulatory Systems
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Fig. 21-2a, p. 420
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Fig. 21-2a, p. 420
capillary beds of gills
ventricleheart
rest of body
atrium
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Fig. 21-2b, p. 420
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Fig. 21-2b, p. 420
lungs
right atrium
left atrium
ventricle
rest of body
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Fig. 21-2c, p. 420
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Fig. 21-2c, p. 420
lungs
right atrium
left atrium
right ventricle left ventricle
rest of body
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Animation: Circulatory systems
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21.3 Human Cardiovascular System
The human heart has four chambers, and pumps blood through two separate circuits: pulmonary and systemic
Each circuit has a network of blood vessels that carry blood between the heart and capillary beds
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Types of Blood Vessels
Artery • Large-diameter blood vessel that carries blood
from the heart to an organ
Arteriole • Blood vessel that carries blood from an artery to a
capillary bed
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Types of Blood Vessels
Venule • Small-diameter blood vessel that carries blood
from capillaries to a vein
Vein • Large-diameter vessel that returns blood to the
heart
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The Pulmonary Circuit
Oxygen-poor blood collected by the right atrium is pumped from the right ventricle, through pulmonary arteries, to the lungs
In the lungs, blood gives off CO2 and picks up O2
Oxygen-rich blood returns through pulmonary veins to the left atrium
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The Systemic Circuit
Oxygen-rich blood collected by the left atrium is pumped from the left ventricle, through the aorta, to capillary beds of the body
Aorta • Large artery that receives blood pumped out of
the left ventricle
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The Systemic Circuit
At capillary beds in the body, blood gives up O2 and picks up CO2
• Most blood flows through only one capillary bed, but blood from gut capillaries also passes through liver capillaries before retuning to the heart
Oxygen-poor blood returns to the right atrium
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The Human Cardiovascular System
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Fig. 21-3a, p. 421
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Fig. 21-3a, p. 421
Heart
atrium ventricle
veins arteries
venules arterioles
capillaries
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Fig. 21-3b, p. 421
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Fig. 21-3b, p. 421
right pulmonary artery left pulmonary artery
capillary bed of right lung
capillary bed of left lung
pulmonary trunk
to systemic circuit
from systemic circuit
pulmonary veins
heart
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Fig. 21-3c, p. 421
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Fig. 21-3c, p. 421
capillary beds of head, upper extremities
to pulmonary circuit
aorta
from pulmonary circuit
heart
capillary beds of other organs in thoracic cavity
capillary bed of liver
capillary beds of intestines
capillary beds of other abdominal organs and lower extremities
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Animation: Human blood circulation
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21.4 The Human Heart
Structures of the human heart• Pericardium protects the heart• Each half of the heart has two chambers: an
upper atrium and a lower ventricle • Superior and inferior vena cava deliver blood to
the right atrium• Pulmonary veins deliver blood to the left atrium• Atrioventricular (AV), aortic, and pulmonary
valves prevent blood from moving backwards
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The Human Heart
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Fig. 21-4, p. 422
aorta (to body)superior vena cava (flow from head, arms) trunk of pulmonary
arteries (to lungs)pulmonary valve (closed) aortic valve (closed)right pulmonary veins (from lungs) left pulmonary veins
(from lungs)
Right Atrium Left Atrium
right AV valve (open)
left AV valve (open)
Right Ventricle Left Ventricle
inferior vena cava (from trunk, legs)
cardiac muscle
septum
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Fig. 21-4, p. 422
trunk of pulmonary arteries (to lungs)
pulmonary valve (closed)
aorta (to body)
aortic valve (closed)
left AV valve (open)
right AV valve (open)
superior vena cava (flow from head, arms)
Right Atrium Left Atrium
Right Ventricle Left Ventricle
inferior vena cava (from trunk, legs)
cardiac muscle
septum
right pulmonary veins (from lungs) left pulmonary veins
(from lungs)
Stepped Art
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Animation: The human heart
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The Cardiac Cycle
Cardiac cycle • Sequence of contraction and relaxation of heart
chambers that occurs with each heartbeat
Signals from the cardiac pacemaker trigger contraction of the atria, then the ventricles • Atria fill ventricles; ventricular contraction drives
blood flow away from the heart • Closing heart valves cause heartbeat sounds
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The Cardiac Cycle
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Fig. 21-5, p. 423
1 Relaxed atria fill. Fluid pressure opens AV valves and blood flows into the relaxed ventricles.
2 Atrial contraction squeezes more blood into the still-relaxed ventricles.
3 Ventricles start to contract and the rising pressure pushes the AV valves shut. A further rise in pressure causes the aortic and pulmonary valves to open.
4 As blood flows into the arteries, pressure in the ventricles declines and the aortic and pulmonary valves close.
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Fig. 21-5, p. 423
4 As blood flows into the arteries, pressure in the ventricles declines and the aortic and pulmonary valves close.
Stepped Art
1 Relaxed atria fill. Fluid pressure opens AV valves and blood flows into the relaxed ventricles.
2 Atrial contraction squeezes more blood into the still-relaxed ventricles.
3 Ventricles start to contract and the rising pressure pushes the AV valves shut. A further rise in pressure causes the aortic and pulmonary valves to open.
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Animation: Cardiac cycle
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Setting the Pace of Contractions
Spontaneous signals from the cardiac pacemaker cause cardiac muscle fibers of the heart wall to contract in a coordinated rhythm• Gap junctions connect cardiac muscle cells
Cardiac pacemaker • Group of heart cells (SA node) that emits
rhythmic signals calling for atrial contraction• Signals AV node to begin ventricular contraction
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The Heart’s Signaling System
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Fig. 21-6, p. 423
SA node (cardiac pacemaker)
AV node
fibers that relay signals
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Animation: Cardiac conduction
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Animation: Bony fish respiration
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SA Node Malfunctions: Cardiac Arrest
CPR increases chances of survival
Cardiopulmonary resuscitation (CPR) • Life-saving technique that keeps oxygen flowing
to tissues when the heart stops beating; involves mouth-to-mouth respiration, chest compressions
Defibrillator • Device that administers an electric shock to the
chest wall to reset the SA node, restart the heart
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Video: ABC News: Second-chance heart
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21.5 Blood and Blood Vessels
An average adult has about 4.5 liters of blood, consisting of plasma, red blood cells, white blood cells, and platelets
Plasma • Fluid portion of blood, composed of water with
dissolved ions and molecules • Transports gases, nutrients, wastes, signaling
molecules, plasma proteins
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Blood Cells and Platelets
Blood cells and platelets arise from stem cells in bone marrow
Red blood cells • Hemoglobin-filled blood cells that transport
oxygen and, to a lesser extent, carbon dioxide• Lack nucleus and organelles, live about 4 months
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Blood Cells and Platelets
White blood cells (leukocytes) • Various kinds function in housekeeping (digest
debris) and defend against viruses, bacteria, and other pathogens
Platelet • Cell fragment that patches tears in blood vessels
and initiates blood clotting
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Components of Blood
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Fig. 21-7, p. 424
plasma
blood cells
red blood cell
white blood cell platelet
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Animation: Vertebrate lungs
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Animation: Bird respiration
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Rapid Transport in Arteries
Blood is pumped from ventricles into arteries under high pressure• Muscular, elastic walls propel blood forward when
ventricles are relaxed
Pulse • Brief stretching of artery walls that occurs when
ventricles contract
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Blood Pressure
Blood pressure is higher in the systemic circuit than in the pulmonary circuit• Left ventricle is stronger than the right
Blood pressure • Pressure exerted by blood against the walls of
blood vessels• Highest in arteries, lowest in veins
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Measuring Blood Pressure
Normal blood pressure is about 120/80 mm Hg (systolic/diastolic)
Systolic pressure • Blood pressure when ventricles are contracting
Diastolic pressure • Blood pressure when ventricles are relaxed
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Adjusting Resistance at Arterioles
Depending on need, the body alters the distribution of blood flow through the body by adjusting the diameter of arterioles• Example: more blood sent to gut when eating
Smooth muscles in arteriole walls widen or narrow vessel diameter in response to nervous and endocrine signals• Vasodilation, vasoconstriction
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Exchanges at Capillaries
Capillary beds exchange materials between blood and interstitial fluid around cells• Gases diffuse across the plasma membrane• Blood pressure at arterial ends of capillary beds
causes plasma to leak out, carrying oxygen, ions, and nutrients
• Osmosis at venous ends of capillary beds causes water from interstitial fluid to enter blood, carrying wastes (excess fluid becomes lymph)
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Blood Vessel Structure
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Fig. 21-8a, p. 424
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Fig. 21-8a, p. 424
outer coat
smooth muscle
basement membrane
elastic tissue elastic tissue
A Artery
endothelium
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Fig. 21-8b, p. 424
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Fig. 21-8b, p. 424
outer coat
smooth muscle rings over elastic tissue
basement membrane endothelium
B Arteriole
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Fig. 21-8c, p. 424
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Fig. 21-8c, p. 424
basement membrane endothelium
C Capillary
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Fluid Movement at a Capillary Bed
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Fig. 21-9, p. 425
capillaryblood to
venule
high pressure causes outward flow
inward-directed osmotic movement
cells of tissue
B
blood from arteriole
A
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Back to the Heart
Venules converge into veins, which return blood to the heart
Veins are a blood volume reservoir (hold up to 70% of blood)
Skeletal muscles help blood move; valves in veins keep blood from moving backward
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Skeletal Muscle’s Effect on a Vein
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Fig. 21-10, p. 426
blood flow to heart
valve open
contracting skeletal muscle
valve closed
vein
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Animation: Major human blood vessels
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Animation: Vessel anatomy
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Animation: Hemostasis
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21.6 Animal Respiration
The respiratory system, working with the circulatory system, uses the process of respiration to exchange gases across a respiratory surface
Respiration • Physiological process by which animals obtain
oxygen and get rid of waste CO2
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The Respiratory Surface
Gases enter and leave an animal body across a respiratory surface; the area of a respiratory surface affects the rate of exchange
Respiratory surface • Moist surface across which gases are exchanged
between animal cells and the air
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Invertebrate Respiration
In some aquatic animals, the respiratory surface may be the body surface or external gills
Integumentary exchange • Gas exchange across the outer body surface
Gills • Folds or body extensions that increase the
surface area for respiration
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Invertebrate Respiration
Insects, the most successful air-breathing land invertebrates, have a hard surface and a tracheal respiratory system
Tracheal system • Branching tubes that deliver air from the body
surface to tissues of insects and some other land arthropods with hard exoskeletons
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Gills and Fish Respiration
Most fishes have internal gills that extend from the back of the mouth to the body surface• Water flows into the mouth and over gill filaments
containing blood vessels• Water and blood flow in opposite directions,
maximizing the amount of oxygen that diffuses into the blood
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Gills and Fish Respiration
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Fig. 21-11a, p. 426
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Fig. 21-11a, p. 426
FISH GILLWater flows in through mouth.Water flows
over gills, then out.
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Fig. 21-11b, p. 426
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Fig. 21-11b, p. 426
gill arch
gill filament
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Fig. 21-11c, p. 426
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Fig. 21-11c, p. 426
respiratory surface
direction of water flow
direction of blood flow
oxygenated blood back toward body
oxygen-poor blood from deep in body
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Evolution of Paired Lungs
All mammals and birds, most amphibians, and some fishes have lungs, which provide a large surface area for gas exchange
Lungs • Internal saclike organs; serve as the respiratory
surface in most land vertebrates and some fish
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Examples of Vertebrate Lungs
Amphibians exchange gases across their skin and force air into and out of small lungs
Reptiles, birds, and mammals use skeletal muscles to draw air into lungs• Birds have a unique adaptation for flight: air sacs
that constantly move fresh air through the lungs• Mammals inhale fresh air that mixes in lungs with
residual, oxygen-depleted air
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Examples of Vertebrate Lungs
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Fig. 21-12, p. 427
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Fig. 21-12a, p. 427
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Fig. 21-12a, p. 427
lung
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Fig. 21-12b, p. 427
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Fig. 21-12b, p. 427
anterior air sacs
lung
posterior air sacs
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Animation: Examples of respiratory surfaces
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Animation: Frog respiration
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Animation: Diffusion, osmosis, and countercurrent systems
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21.7 Human Respiratory Function
When you take a breath, air flows in through nasal cavities, the pharynx, the larynx, the trachea, bronchi, and bronchioles, which end at alveolar sacs deep inside the lungs
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Lungs
Two cone-shaped lungs are located in the thoracic cavity, one on each side of the heart, enclosed and protected by the rib cage
Two layers of pleural membrane cover the lung’s outer surface and line the thoracic cavity
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Structures of the Human Respiratory System
Pharynx • Throat; opens to airways and digestive tract
Larynx • Short airway containing vocal cords (voice box);
contraction of vocal cords changes the size of the glottis
Glottis • Opening formed when the vocal cords relax
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The Glottis and Vocal Cords
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Fig. 21-14, p. 428
glottis open
glottis closed
vocal cords
glottis (closed)
epiglottis
tongue’s base
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Fig. 21-14d, p. 428
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Fig. 21-14d, p. 428
vocal cords
glottis (closed)
epiglottis
tongue’s base
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Animation: Vocal chords
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Structures of the Human Respiratory System
Epiglottis • Tissue flap at the entrance to the larynx• Folds down to prevent food from entering the
trachea when you swallow
Trachea • Major airway leading to the lungs; windpipe• Branches into two bronchi, each leading to a lung
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Structures of the Human Respiratory System
Bronchus (bronchi) • Airway connecting the trachea to a lung
Bronchiole • Small airway leading from bronchus to alveoli
Alveoli (alveolus) • Tiny, thin-walled air sacs• Site of gas exchange in the lung
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Structures of the Human Respiratory System
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Fig. 21-13a, p. 428
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Fig. 21-13a, p. 428
nasal cavity
pharynx (throat)
epiglottis
larynx (voice box)
trachea (windpipe)
left lung
bronchus
bronchiole
diaphragm
intercostal muscle
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Fig. 21-13b, p. 428
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Fig. 21-13b, p. 428
alveolar sac (sectioned)
alveoli
bronchiole
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Animation: Human respiratory system
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How You Breathe
Actions of the diaphragm and intercostal muscles allow you to breathe
Diaphragm • Dome-shaped muscle at base of thoracic cavity
that alters thoracic cavity size during breathing
Intercostal muscles • Muscles between the ribs; help alter the size of
the thoracic cavity during breathing
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The Respiratory Cycle
Breathing in (inhalation) and breathing out (exhalation) is one respiratory cycle
Respiratory cycle • One inhalation and one exhalation• Inhalation is always active (requires energy)• Exhalation is usually passive
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Muscle Actions During a Respiratory Cycle
In inhalation, muscle contractions expand the chest cavity; lung pressure decreases below atmospheric pressure, and air flows in
In exhalation, muscles of respiration relax; the volume of thoracic cavity and lungs decrease, pushing air out of lungs
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Muscle Actions During a Respiratory Cycle
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Fig. 21-15, p. 429
air flows in air flows out
rib cage expands
rib cage gets smaller
diaphragm contracts and flattens downward
diaphragm relaxes, moves upward
A Inhalation B Exhalation
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Animation: Respiratory cycle
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Control of Breathing
A respiratory center in the brain stem controls depth and rate of normal breathing• Signals diaphragm and intercostal muscles to
begin inhalation, 10 to 14 times per minute
When activity increases CO2 production, receptors in arteries and the brain signal for an increase in rate and depth of breathing
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Exchanges at the Respiratory Membrane
Blood carries gases between lungs and body tissues
Fused basement membranes of alveolar and pulmonary capillary cells form the respiratory membrane
Oxygen and carbon dioxide diffuse across the respiratory membrane, each following its own concentration gradient
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Alveoli and the Respiratory Membrane
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Fig. 21-16, p. 430
cells of alveolar wall
cells of capillary wallO2
CO2 fused basement membranes of both epithelial cell layers
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Oxygen Transport
Oxygen follows its concentration gradient from alveolar air spaces into pulmonary capillaries, then into red blood cells, where it binds reversibly with hemoglobin
In capillary beds, hemoglobin releases oxygen, which diffuses across interstitial fluid into cells
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Carbon Dioxide Transport
CO2 diffuses from cells into interstitial fluid, then into blood
Enzymes in red blood cells converts most CO2 into bicarbonate, which dissolves in plasma• Converted back to CO2 in pulmonary capillaries
CO2 diffuses from pulmonary capillaries into air in alveoli, then is expelled
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Animation: Structure of an alveolus
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Animation: Pressure-gradient changes during respiration
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Animation: Changes in lung volume and pressure
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Animation: Structures that function in human respiration
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Animation: Partial pressure gradients
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21.8 Cardiovascular and Respiratory Disorders
Problem: too few or too many blood cells
Anemia • Red blood cells are impaired or fewer than normal• Decreases oxygen delivery to cells• Caused by sickle cell anemia, malaria, lack of iron
Leukemia • Cancer that increases white blood cell numbers• Impairs normal blood functions
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Good Clot, Bad Clot
Hemophilia impairs normal blood clotting
Other disorders cause dangerous clotting• Thrombus: a clot that forms in a vessel and
remains there• Embolus: a clot that forms in a blood vessel,
then breaks loose
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Atherosclerosis and Hypertension
Atherosclerosis and hypertension may cause heart attack or stroke
Atherosclerosis • Artery interior narrows because of lipid deposition
and inflammation• LDLs deposit cholesterol; HDLs remove it
Hypertension (a silent killer)• Chronically high blood pressure (above 140/90)
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Atherosclerosis and Hypertension
Heart attack • Heart cells die because of impaired blood flow
through coronary arteries
Stroke • Brain cells die because a clot or vessel rupture
disrupts blood flow within the brain
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Atherosclerosis
Normal artery; artery with atherosclerotic plaque
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Two Treatments for Blocked Coronary Arteries
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Fig. 21-18, p. 431
vein from leg used to bypass blockage
blocked coronary artery
plaque flattened by balloon angioplasty
stent (metal mesh) placed to keep artery open
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Fig. 21-18a, p. 431
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Staying Healthy
Maintaining a moderate weight, eating a healthy diet, and getting regular exercise can reduce the risk of many cardiovascular disorders
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Respiratory Disorders
Ciliated and mucus-secreting epithelial cells lining bronchioles help protect us from respiratory infections such as bronchitis
Cigarette smoke damages the epithelial lining• Smoking is the main cause of emphysema, an
irreversible loss of lung function
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Emphysema: The Effect of Smoking
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Smoking’s Impact
“Tobacco remains the only legal consumer product that kills half its regular users”• Smoking kills 4 million people each year• May rise to 10 million by 2030
Direct medical costs of treating tobacco induced disorders in the US alone: $22 billion each year
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Major Risks of Smoking and Benefits of Quitting
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21.9 Impacts/Issues Revisited
Despite advertisers’ claims, nicotine in tobacco products causes premature aging and interferes with sexual function• Causes wrinkles by disrupting blood flow to skin• Directs blood flow away from sex organs,
contributing to male erectile dysfunction and inhibition of female sexual response
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Digging Into Data:Risks of Radon