biology @ iit-kanpur · 2011-01-07 · biology @ iit-kanpur “while the entire world is investing...
TRANSCRIPT
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Biology @ IIT-Kanpur
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“While the entire world is investing heavily in biology, IITK has not even started. Lack of funds is the main problem”
From the “Report of the Committee on MEGA PROJECTS” submitted in the year 2000
http://www.iitk.ac.in/drpg/megaprojects.PDF
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http://www.iitk.ac.in/drpg/megaprojects.PDF
From the “Report of the Committee on MEGA PROJECTS” submitted in the year 2000
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Mr. Arun Shourie pledged Rs. 11.9 crores under MPLADS scheme
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National Advisory Committee
BSBE – The planning stage
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BSBE Core Committee
BSBE – A multidisciplinary initiative
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BSBE Department was established on 13th
September 2001
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The new BSBE Complex was inaugurated by Prime Minister Vajpayee in October 2003
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2001-2002
2004 2006
2010
Team BSBE
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Genetics, Genomics & Developmental Biology
BSBE
Structural & Computational Biology
Bioengineering(Cell separation/ Tissue engineering, Biomechanics and Bioelectronics)
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Facilities in BSBE
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Cancer genetics using model organisms
Germ Cell Development
Plant-pathogen interactions using RNAi
Neurodegenerative disorders
Mouse model for osteoarthiritis
Enzyme mechanism using structural biology
Computational studies of membrane proteins
Controlled drug delivery
Biomaterials and Tissue Engineering
Current Research at BSBE
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BSBE
Chemistry
Chemical Engineering
Electrical Engineering
Centre for Environment Science
& Engineering
Materials Science & Engineering
Mechanical Engineering
Computer Science & Engineering
Industrial & Management Engineering
Australia
Belgium
Japan
Russia
Sweden
United Kingdom
United States
Synergy with other departments at IIT-K
International Collaboration
At National level
Other IITs, Universities, CSIR Labs, Industries and also with Medical Community
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• Chemistry – Synthesis & structure
• Physics– Biophysics & imaging
• Materials– Prosthesis & Biomaterials
• Mechanics– Biomechanics & Devices– Bio-MEMS
• Chemical Engineering– Nanostructure & Bio-mimetics
Intellectual & Technical Capital in Engineering & Natural Sciences at IITK
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S. Ganesh
Human Molecular Genetics
CNS DisorderIdiopathic Epilepsies
Cardiovascular DisorderMyocardial Infraction
Developmental DisorderCleft lip/cleft palate
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R. Sankararamakrishnan
• Genome-wide identification of aquaporin genes in plants
• Interactions involving Asx/Glx residues in providing stability to protein structures
• Protein-protein interactions in apoptotic pathway: MD simulations
• GPCR peptide hormones: Conformational studies in lipid bilayers
• Alternate initiation in translation: nonAUG start codons and AUG codons with weak Kozak context
Structural Bioinformatics and Computational Biology
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Balaji PrakashWellcome Trust Senior
Research Fellow
•Structure-function relationships in
• GTPases involved in ribosome biogenesis
• Ser/Thr Kinases of M.Tuberculosis
• Rel family of proteins
Structural Biology
X-ray crystallography, Biochemistry, Bioinformatics
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Anupam Pal
•Computational modeling of muscle and biofluid mechanics
•High performance computing methods
•Image processing and data visualization
Biomechanics and Modeling
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• Biomaterials (biodegradable polymers)
• Tissue Engineering (musculoskeletal}
• Drug Delivery Systems (Cancer therapy)
• Nanotechnology (polymer nanofiber for tissue engineering and drug delivery)
Dhirendra S. Katti
Tissue Engineering
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K SubramaniamWellcome Trust Senior
Research Fellow
• Germ cell development – C. elegans model • Functional genomics approaches to
Parasitic nematode biology
Wild type Transgenic
Germ cell development and parasitic nematode biology
Tobacco plant
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Human disease models in animals
Mouse model for Osteoporosis:
Amitabha Bandhopadhyay
BMP2 conditional mutants
Wild type
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Peer-reviewed publications from BSBE
Source: Web of Science
Search term used in the Address field:
Kanpur and Biol* and Bioen* and 208016
Total number of publications in the last nine years: 118
Number of patents filed: 14
DevelopmentDevelopmental BiologyJ. Biol. Chem. Human Mol. GeneticsNucleic Acids Res.Nature ProtocolsProteins: Struct. Func. Bioinf.Protein Sci.BMC Plant Biol.Biochem. Biophys. Res. Commn.BMC Struct. Biol.J. Phys. Chem. BJ. Comp. Chem.Mol. Biochem. Parasitol.AutophagyHuman Mutation
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International/National Grants and Awards
Indo – US Joint Center for Biomaterials
IBM Shared University Resources Grant
Indo-UK Science Bridge in Biopharma
UK – India Education and Research Initiative
National Agricultural Innovation Project
Wellcome Trust International Fellowship (2)
National Bioscience Award for Career Development (3)
Scopus Young Scientist Award
DAE-SRC Outstanding Research Award
B. M. Birla Science Prize
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Programmes offered in BSBE
B. Tech
M. Tech
Ph. D
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BSBE PG program: Some details
No. of Ph. D. students: ~70
No. of M. Tech students: ~ 40
No. of M. Tech students graduated: ~100
No. of students who received Ph. D. degree: ~20
No. of UG students: ~120
No. of students graduated: ~50
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BSBE core courses taught to UG studentsIntroduction to Biological Sciences & Bioengineering
Molecular Biology
Biochemistry
Molecular Biology LAB
Biochemical Engineering
Biochemistry and Biochemical Engineering LAB
Biomaterials
Structural Biology & Bioinformatics
Biomechanics
Structural Biology & Bioinformatics LAB
Biomechanics & Biomaterials LAB
Project
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What is the future of Biology @ IIT-Kanpur ?
Innovation
Education Research
New revised UG program
Enter PG program after B. Sc.
MBBS Graduates
Interdisciplinary
IIT-postdoc progarms
Animal House facility
Interface with Engineering departments
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Fundamental research
Health, Agriculture, drug, diagnosis, product
Research Vision at BSBE