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    1

    Phagocytosis Simple Diffusion Osmosis: the diffusion of water

    The pseupodia are also used for feeding.

    Amoeba sp. engulfs food by phagocytosis.

    Amoeba sp. is a holozoic organisms which

    feed on microscopic organisms such asbacteria.

    The presence of food causesAmoeba

    sp.to advance by extending its pseupodia.

    The pseupodia encloses the food which is

    then packaged in food vacoule.

    The food vacoule fuses with lysosome and

    the food is digested by hydrolitic enzyme

    called lysozyme.

    The resulting nutrients are absorbed into

    the cytoplasm.

    Net movement of molecules or ions from

    a region of higher concentration to a

    region of lower concentration.

    Going down concentration gradient untilan equilibrium is achieved.

    The particles are distibuted equally

    throughout the system.

    The concentration gradient provides

    energy to move the molecules into and

    out of the cells.

    Net movement of freely moving water

    from a region of lower solute

    concentration to a region of higher solute

    concentration through a semi-permeablemembrane.//

    Net movement of water from region

    higher water concentration to a region of

    lower water concentration.//

    Net movement of water from hypotonic

    region to hypertonic region.

    Facilitated Diffusion Active Transport Animal and plant cells in an isotonic solution

    For water soluble molecules//molecules

    which are not soluble in lipids (ions,nucleic acid, amino acids and glucose)

    Carrier Protein

    The carrier protein function by

    binding to the molecules to pass

    through the plasma membrane.

    The molecules move to the carrier

    protein which is specific for the

    molecules.

    Molecules bind with the carrier

    protein at the active site.

    Carrier protein changes its shape and

    pass the molecules through the

    plasma membrane.

    Movement of molecules or ions against

    the concentration gradient across theplasma membranes.

    Requires both carrier proteins and

    expenditure of energy.

    Energy from ATP (adenosine

    triphosphate) that is generated during

    respiration in the mitochondria.

    Has active sites which bind to the ATP

    molecules. The carrier protein changes shape when

    the phosphate group from the ATP

    molecule binds to it

    Then the solute is moved across the

    plasma membrane.

    Solution in which the solute concentration

    is equal to that of the cytoplasmic fluid. Water diffuse in and out of the cells at

    equal rate.

    No net movement of water.

    Cells retain its normal shape.

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    Hypotonic solution Hypertonic solution Preservation of fish and vegetables

    Concentration of solute outside a cell is lower

    than concentration of solute inside cell.

    Animal cells Is said to be hypotonic solution.

    Cell placed in hypotonic solution.

    Net movement of water into the cells via

    osmosis.

    Cell swells up.

    When extremely hypotonic, cells will

    eventually burst

    Cannot withstand the osmotic pressure

    because of thin plasma membrane.

    E.g : red blood cells (haemolysis)

    Plant cells

    Do not burst

    Rigid cell wall.

    Water diffuse into vacoule of cell viaosmosis.

    Cell swells up and becomes turgid

    Tugor pressure in plant.

    Supporting the plant.

    The concentration of solute in the solution is

    higher than the concentration of solutes within

    the cell.

    Animal cells

    Net movement of water from inside to

    the outside of the cell.

    Cells shrink//shrivel, internal pressure

    decrease.

    Red blood cells immersed in hypertonic

    solution , the cell shrink and the plasma

    membrane crinkles up. Cell undergone crenation.

    Plant cells

    Water diffuse out via osmosis.

    Vacoule and cytoplasm shrink and plasma

    membrane pulls away from the cell wall.

    This process called plasmolysis.

    Cell becomes flaccid.

    Fish

    Fish is covered by salt solution which is

    hypertonic to body fluid/cell/tissue.

    More water diffuses out from tissues intosalt solution via osmosis.

    Fish becomes hydrated.

    Prevents bacterial growth in fish tissues.

    Bacteria cells are also

    plasmolysed//crenated.

    Prevent decay/last longer.

    Vegetables

    Vegetables are immersed in vinegar which

    is acidic//has low pH.

    Vinegar diffuses into vegetables tissues.

    Vegetables tissues becomes acidic//has

    low pH.

    Prevents bacterial growth in tissues.

    Preventing decay//last longer.

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    Differences between facilitated diffusion and active transport

    Facilitated diffusion

    But

    Active transport

    D1

    E1

    Down the concentration gradient

    Molecules moves from higher concentration to lowerconcentration

    Against the concentration gradient

    Molecules moves from lower concentration tohigher concentration

    D2

    E2

    Molecules move in both direction across the plasma

    membrane

    Molecules can move through pore protein or/and carrier

    protein

    Molecules move in one direction across the plasma

    membrane

    Molecules move through carrier protein

    D3

    E3

    No ATP/energy used

    Molecule can move through pore protein without binding

    ATP/energy is used

    Energy needed for binding/bind with active site

    D4 Molecules need carrier protein and pore protein to helpthe movement

    Need carrier protein only to help movement

    D5 Could achieve equilibrium Will not achieve equilibrium/result in accumulation

    D6 Not depended in cellular respiration Depend on cellular respiration/energy

    Similarities between facilitated diffusion and

    active transport

    The Importance of water General characteristics of enzymes

    Both (ways of transportation)need carrier

    protein.

    To bind with

    molecules/ion/substrate/examples

    Both transport specific molecules only.

    Because the carrier protein have specific

    site to certain molecules.

    Both processes occur in living cell.

    Because carrier protein need/can change

    shape to allow substances to move across.

    Water is a polar molecule and act as a

    solvent.

    Transport medium in the blood,

    lymphatic, excretory and digestive

    systems and in the vascular tissues of

    plant.

    As a medium for biochemiocal reaction.

    Helps in lubricant. Regulates body temperature.

    Alter or speed up the rates of chemical

    reactions

    Remain unchanged at the end of reaction.

    Do not destroyed by reactions they

    catalysed.

    Have specific sites called active site to

    bind with specific substrates.

    Needed in small quantities.

    Reaction are reversible

    Can be slowed down or stopped by

    inhibitors. E.g: lead and mercury

    Require helper molecules, called

    cofactors.

    Inorganic cofactor : ferum, copper

    Organic cofactor: water soluble vitamins,

    B vitamins .

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    Extracellular enzyme Lock and key hypothesis Effects of temperature on enzyme activity

    Extracellular enzyme is produced in a cell,

    then packed and secreted from the cell.

    It catalyses its reaction outside the cell.

    An example is amylase.

    The instruction for making the

    extracellular enzyme is transcribed from

    the deoxyribonucleic acid

    (DNA) to ribonucleic acid (RNA) in the

    nucleus.

    The RNA then leaves the nucleus through

    the nuclear pore and attaches itself to the ribosome

    located on the endoplasmic reticulum.

    When the synthesis of the enzymes is

    completed it is encapsulated in a

    transport vesicle which fuses with the

    golgi body.

    In the golgi body, the enzyme is further

    modified before being packed in asecretory vesicle.

    The secretory vesicle transports the

    enzyme to the plasma membrane, where

    it fuses with it and the enzyme is released

    outside the cell.

    The substrate molecule fits into the active

    site of the enzyme molecule.

    The substrate is the key that fits into the

    enzyme lock.

    Various types of bonds such as hydrogen

    and ionic bonds hold the substrate

    in the active site forming the enzyme-

    substrate complex.

    Once the complex is formed, the enzyme

    changes the substrate to its product.

    The product leaves the active site. The enzyme is not altered by the reaction

    and it can be reused.

    At low temperature, reaction takes place

    slowly.

    As temperature increases, movement of

    substrate increase.

    Increase their chances of colliding with

    each other and with the active site of the

    enzymes.

    At optimum temperature, the reaction is

    at maximum rate.

    Beyond the optimum temperature, rate of

    reaction will not increase. Bonds that hold enzyme molecules begin

    to break.

    Actives sites destroyed.

    Enzyme denatured.

    Prophase Metaphase Anaphase

    Chromosomes in the nucleus condense.

    Chromosomes appear shorter and thicker.

    Consist of sister chromatid joined at the

    centromere.

    Spindle fibres begin to form.

    Centrioles migrate at opposite poles.

    At the end, nucleolus disappears and the

    nuclear membrane disintegrates.

    Chromosomes align at the metaphase

    plate//equatorial plate//middle of the

    cell.

    Mitotic spindle are fully formed.

    Two sister chromatids are still attached to

    one another at the centromere.

    Ends when the centromere divides.

    Two sister chromatids separate at the

    centromere.

    Sister chromatids pulled apart at opposite

    poles.

    Chromatids are referred to as daughter

    chromosomes.

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    Disadvantages of cloning Meiosis I Meiosis II Long-term side effects are not yet known.

    May undergo natural mutations. Disrupt

    the natural equilibrium of an ecosystem.

    Clones do not show any genetic

    variations.

    Has the same level of resistance towards

    certain disease.

    Certain transgenic crops contain genes

    that are resistant to herbicides.

    These genes may be transferred to weeds

    through viruses. These weeds would then

    become resistant to herbicides.

    Cloned animals has shorter lifespan.

    1. During prophase I, homologous

    chromosomes pair up (synapsis) and

    crossing over between non sister

    chromatids occurs.

    2. During Metaphase I, homologous

    chromosomes align at the metaphase

    plate (equator, middle) of the cell.

    3.

    During Anaphase I, homologous

    chromosomes separates and move to

    opposite poles. Sister chromatids are still

    attached together and move as a unit.

    4. At the end of Telophase I, two haploid

    daughter cells are formed. Each daughter

    cell has only one of each type of

    chromosomes, either the paternal or

    maternal chromosomes.

    1. During Prophase II, synapsis of

    homologous chromosomes and crossing

    over between non-sister chromatids do

    not take place.

    2. During Metaphase II, chromosomes

    consisting of two sister chromatids align

    at the metaphase plate (equator/middle)

    of cell.

    3. During Anaphase II, sister chromatids

    separate, becoming daughter

    chromosomes that move to opposite

    poles.

    4. At the end of Telophase II, four haploid

    daughter cells are formed. Each daughter

    cell has the same number of

    chromosomes as the haploid cell

    produced in Meiosis I, but each has only

    one of the sister chromatids.

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    Digestion in mouth Digestion in stomach Digestion in small intestine

    Secretion of saliva by three pairs of

    salivary glands

    Saliva contains the enzyme salivary

    amylase

    Begins the hydrolysis of starch to maltose.

    Starch + water maltose

    An additional digestive process occurs

    further along the alimentary canal to

    convert maltose to glucose.

    pH is maintained at 6.5-7.5

    Epithelial lining of the stomach contains

    gastric glands.

    These glands secrete gastric juice.

    Consists of mucus, HCL and enzymepepsin and renin.

    HCL make the pH around 2.0.

    High acidity destroy bacteria.

    Acidity stop the activity of salivary

    amylase enzyme.

    Protein + water polypeptides

    Renin coagulate milk by converting the

    soluble milk protein, caseinogen into

    soluble caesin.

    Stomach contents become a semi-fluid

    called chyme.

    Chyme gradually enter the duodenum.

    Duodenum received chyme from stomach

    and secretion from the gall bladder and

    pancreas.

    Starch, protein and lipids are digested.

    Bile which produced by the liver and

    stored in the gall bladder enter the

    duodenum via the bile duct.

    Bile helps neutralise the acidic chyme and

    optimise the pH for enzyme action in

    duodenum.

    Bile salts imulsify lipids, breaking them

    down into tiny droplets.

    Providing high TSA for digestion.

    Pancreas secrete pancreatic juice into

    duodenum via pancreatic duct.

    Pancreatic juice contains pancreatic

    amylase, trypsin and lipase.

    Pancreatic amylase complete the

    digestion of starch to maltose. Trypsin digests polypeptides into

    peptides.

    Lipase complete the digestion of lipid into

    fatty acid and glycerol.

    Glands in the ileum (small intestine)

    secrete intestinal juice which contain

    digestive enzyme needed to complete the

    digestion of peptides and disaccharides.

    Peptides digested by erepsin into amino

    acids.

    Maltose digested by maltase into glucose.

    Disaccharides digested by its own enzyme

    into monosaccharides and glucose.

    Salivary amylase

    pepsin

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    Digestion of cellulose by ruminant Digestion of cellulose by rodent Digestion

    Partially chewed food is passed to the

    rumen (largest compartment of the

    stomach).

    Cellulose is broken down by cellulaseproduced by bacteria.

    Part of the breakdown products are

    absobed by bacteria, the rest by the host.

    Food enters the reticulum.

    Cellulose undergoes further hydrolysis.

    The content of the reticulum, called the

    cud, is then regurgitated bit by bit into the

    mouth to be thoroughly chewed. Helps soften and break down cellulose,

    making it more accessible to further

    microbial action.

    The cud is reswallowed and moved to the

    omasum.

    Here, the large particles of food are

    broken down into smaller pieces by

    peristalsis.

    Water is removed from the cud.

    Food particles moved into obamasum, the

    true stomach of the ruminant. (e.g : cow).

    Gastric juice complete the digestion of

    protein and other food substances.

    The food then passes through the small

    intestine to be digested and absorbed inthe normal way.

    Caecum and appendix are enlarged to

    store the cellulose-digesting bacteria.

    The breakdown products pass through the

    alimentary canal twice. The faeces in the first batch are usually

    produced at night.

    Faeces are then eaten again. To absorb

    the products of bacterial breakdown.

    The second batch of the faeces are harder

    and drier.

    Allows rodent (give example) to recover

    the nutrients initially lost with the faeces.

    Protein

    - In stomach, pepsin breakdown

    protein into polypeptides.

    -

    HCL being secreted to provide acidicmedium for the digestion to occur.

    - In duodenum, trypsin breakdown

    polypeptides into peptides.

    - In small intestine, arepsin break dwon

    peptides into amino acids.

    Fats

    -

    Bile salts breaking up fats into smallfat droplets in the duodenum.

    - In duodenum/small intestine, lipase

    breaks lipids into fatty acids and

    glycerol.

    Carbohydrates

    - In mouth, salivary amylase hydrolyse

    starch into maltose.

    - In duodenum, pancreatic amylase

    hydrolyse starch into maltose.

    - In small intestine, maltase hydrolyse

    maltose into glucose.

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    Absorption of digested food Assimilation of digested food Formation faeces

    Absorption of digested food occur in the

    ileum.

    Glucose/amino acids initially diffuse into

    blood capillaries. The remaining of the glucose/amino acids

    actively transport into blood capillaries.

    All blood capillaries converge into hepatic

    portal vein, which lead to the liver (and

    transport to all parts o fthe body).

    Glycerol and fatty acids diffuse to the

    epithelial cell which lining the ileum) and

    combine to form fat droplets. Fatty acids and glycerol then enter the

    lacteal (lymphatic system).

    Return back to the blood stream at left

    subclavian vein.

    Explain the assimilation of glucose and amino acid

    in body cells.

    Glucose is oxidised to produce energy,carbon dioxide and water by cellular

    respiration.

    Amino acid is used to synthesis

    protoplasm (the component of cell). By

    this way new cells will be synthesised

    causing growth.

    Amino acid also can be used to synthesis

    enzyme, hormone or antibody.

    Faeces which contain dead cells that are

    shed from intestinal linings, toxic

    substances and bile pigments enter the

    colon by action of peristalsis. In colon, more water is absorbed. The

    undigested food residues harden to

    become faeces.

    Faeces contain undigestible residues that

    remain after the process of digestion and

    absorption of nutrients that take place in

    the small intestine.

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    Photosynthesis mechanism Photosynthesis mechanism Uses of enzyme (Chapter 4)

    The formation of starch in plants is by the

    process ofphotosynthesis which occurs in

    chloroplasts.

    The two stages in photosynthesis are thelight and dark reactions.

    Light reaction:

    P3:Takes place in grana.

    P4: Chlorophyll captures light energy

    which excites the electrons of chlorophyll

    molecules to higher energy levels.

    P5: In the excited state, the electrons can

    leave the chlorophyll molecules. P6: Light energy is also used to split water

    molecules into hydrogen ion (H+) and

    hydroxyl ions (OH-) (Photolysis of water).

    P7: The hydrogen ions then combine with

    the electrons released by chlorophyll to

    form hydrogen atoms.

    P8: The energy from the excited electrons

    is used to form energy-rich molecules of

    adenosine triphosphate /ATP.

    P9: Hydroxyl ion loses an electron to forma hydroxyl group. This electron is then

    received by chlorophyll.

    P10: The hydroxyl groups then combine to

    form water and gaseous oxygen.

    Dark Reaction:

    P11: Take place in stroma.

    P12: Do not require light energy.

    P13: The hydrogen atoms are used to fixcarbon dioxide in a series of reactions

    catalysed by photosynthetic enzymes

    P14: and caused the reduction of carbon

    dioxide into glucose.

    P15: The glucose monomers then undergo

    condensation to form starch which is

    temporarily stored as starch grains in the

    chloroplasts.

    Enzymes are used as biological

    detergents.

    Protease degrades coagulated proteins

    into soluble short-chain peptides. Lipase degrades fat or oil stains into

    soluble fatty acid and glycerol.

    Amylase degrades starch into soluble

    shorter-chain polysaccharides and sugars.

    Enzymes are used in the baking industry.

    Protease is used in the breakdown of

    proteins in flour for the production ofbiscuits.

    Amylase is used in the breakdown of

    some starch to glucose in flour for making

    white bread, buns and rolls.

    Enzymes are used in the medical field.

    Trypsin is used to remove blood clots

    and to clean wounds. Various other enzymes are used in

    biosensors.

    Enzymes are used in industries because:

    They are effective.

    They are cheap and easy to use.

    They can be re-used, thus only small

    amounts are needed.

    They don't require high temperature to

    work, thus this reduces fuel costs.

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    Aerobic respiration Anaerobic respiration in human muscle Anaerobic respiration in yeast

    Continuous supply of oxygen.

    Glucose molecules are oxidised by

    oxygen.

    Complete breakdown of glucose in thepresence of oxygen.

    A large amount of energy released.

    Carbon dioxide and water are produced as

    waste products.

    Most of the nergy released is used to

    synthesise adenosine triphosphate (ATP)

    from adenosine diphosphate (ADP) and

    inorganic phosphate. ATP acts as instant energy source.

    ATP consists of phosphate bonds which

    can be easily broken down to release

    energy.

    ATP ADP + phosphate + energy

    During a vigorous exercise (running), the

    breathing rate is increased.

    This is to supply more oxygen to the

    muscles for rapid muscular contraction. However, the supply of oxygen to muscles

    is still insufficient.

    and the muscles have to carry out

    anaerobic respiration to release energy.

    The glucose is converted into lactic acid,

    with only a limited amount of energy

    being produced.

    An oxygen debt builds up in the body,when no oxygen use in energy production.

    High level of lactic acid in the muscles

    cause them to ache.

    After running, the athlete breathes more

    rapidly and deeply than normal for

    twenty minutes.

    There is recovery period after 10 minutes

    until it reaches 20 minutes when oxygen is

    paid back during aerobic respiration.

    About 1/6 lactic acid is oxidized to carbon

    dioxide, water and energy.

    Yeast normally respires aerobically.

    Under anaerobic condition, yeast carry

    out anaerobic respiration.

    Produces ethanol.

    Process known as fermentation.

    Catalysed by the enzyme zymase.

    - Ethanol produced can be used in

    making wine and beer.

    - In bread making, the carbon dioxide

    released during fermentation of yeast

    causes the dough to rise.

    Similarities between the sturucture of digestive and digestion process of ruminants and rodents

    S1

    Both alimentary canal contains bacteria/protozoa

    P1 To secrete extracellular enzyme//to digest

    P2 To digest cellulose into glucose

    S2 Both have large surface area

    P1 To increase rate of diffusion //hydrolysed food

    Energy released

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    Transport of O2 and CO2 in human body

    (continuation)

    Explain how energy flows through the food chain

    and how it is lost to the environment.

    Colonisation and succession in mangrove

    swamps

    Oxyhaemoglobin dissociates to release

    oxygen.

    Carbon dioxide released by repairingcells can be transported by dissolve

    carbon dioxide in the blood plasma.

    Bind to the haemoglobin.

    As carbaminohaemoglobin.

    In form of bicarbonate ions.

    Carbon dioxide is expelled with water

    vapour from the lung.

    Energy flows through the food chain in one

    direction .

    In the food chain, the plant is the producer,

    the rat is the primary consumer, the snake is

    the secondary consumer and the eagle is the

    tertiary consumer.

    In the food chain, the plant is the producer,

    the earthworm is the primary consumer, the

    bird is the secondary consumer and the

    snake/ eagle is the tertiary consumer. Each

    level of food chain is called a trophic level.

    Energy is transferred from one trophic level

    to another trophic level.

    When energy is transferred from one trophiclevel to another level as much as 90% of the

    chemical energy in the food consumed by

    primary consumer is used for its metabolic

    activities and lost as heat.

    Only 10% of the energy in an organism is

    passed on to the organism at the next trophic

    level.

    The pioneer species of a mangrove

    swamp are the Sonneratia sp. and

    Avicennia sp. The presence of this species gradually

    changes the physical environment of

    the habitat.The extensive root systems

    of these plants trap and collect

    sediments, including organic matter

    from decaying plant parts.

    As time passes, the soil becomes more

    compact and firm. This conditionfavours the growth ofRhizophora sp.

    Gradually the Rhizophora sp. replaces

    the pioneer species.

    The prop root system of the Rhizophora

    sp. traps silt and mud, creating a firmer

    soil structure over time.

    The ground becomes higher. As a result,

    the soil is drier because it is less

    submerged by sea water.

    The condition now becomes more

    suitable for the Bruguiera sp., which

    replaces the Rhizophora sp.

    The buttress root system of the

    Bruguiera sp. forms loops which extend

    from the soil to trap more silt and mud. As more sediments are deposited, the

    shore extends further to the sea. The

    old shore is now further away from the

    sea and is like terresterial ground.

    Over time, terrestrial plants

    like nipah palm and Pandanus sp. begin

    to replace the Bruguiera sp.

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    Green house effects Explain briefly why humans carry out the activity

    as shown in diagram above

    Explain the impacts of the activity shown above

    on the environment

    Green house effect.

    Ultra violet(uv) from solar radiation isabsorbed by the earth and some of them

    is reflected back to the atmosphere in the

    form of heat/infra red.

    Heat or infrared radiation cannot be

    reflected back to the atmosphere.

    Because it is trapped by green house

    gases such as CO2, nitrogen dioxide and

    methane. Heat/infrared warmed the surface of

    earth.

    Earth temperature increases.

    The human population grows rapidly. The

    demands for food and housing areas have

    increased.

    Vast areas of forest are cleared for

    agricultural and commercial purposes.

    Urbanization and industrialization have

    caused more forests to be cleared for

    road construction and housing areas.

    Deforestation is also caused by the

    demands for timber and fuel wood.

    Deforestation causes soil erosion ,

    landslides, flash floods and globalwarming.

    Causes the soil to become loose and less

    stable.

    Without the protection of green plants,

    the soil is exposed to the forces of wind

    and rain.

    The top layer of soil is washed away

    gradually by the rainwater. This is known as soil erosion.

    Soil erosion causes the depletion of

    minerals from the soil, therefore the soil

    becomes infertile and unsuitable for

    agriculture.

    Landslides may happen on steep hillsides

    during heavy rain.

    It is because rainwater flows quickly and

    causes the top layer of the soil to

    crumble.

    Rivers and drains are silted and the flow

    of water is blocked.

    Therefore, water flows inland and this

    causes flash floods in the lower areas

    during rainy seasons.

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    Human blood vessels Circulatory system in fish and human Blood clotting

    Arteries

    - carries blood away from heart

    - transport blood quickly, at high pressure

    - muscle of tissue enables the artery to

    constrict and dilate

    - walls of arteries are strong and elastic,

    have small lumen

    Capillaries

    - thin walled blood vessels

    - allow rapid gaseous exchange via diffusion

    - nutrients, wastes and hormones are also

    exchanged across here- one cell thick

    Veins

    - blood returns from capillaries to heart

    through veins

    - blood flows in low pressure

    - have large lumens and valves (prevent

    back flow)

    Similarities

    - both have closed circulation

    - both have a heart

    Differences

    Fish Human

    Has single circulation Has double circulation

    Heart divides into 2

    chambers

    Heart is divided into 4

    chambers

    Septum is absent Septum is present

    Deoxygenated bloodflows from heart to

    gills

    Deoxygenated bloodflows from heart to

    lungs

    Oxygenated blood

    flows from gills to

    body cells

    Oxygenated blood

    flows from lungs to

    heart

    - clumped platelets, damaged cells, clotting

    factors form activators (thromboplastins)

    - activators together with calcium ions and

    vitamin K, converts prothrombin to

    thrombin

    - thrombin catalyses the conversion of

    soluble protein fibrinogen into insoluble

    fibrin.

    - fibrin is a fibrous protein which combines

    to form a mesh of long threads over the

    wounds, trapping red blood cells and

    sealing the wound.- blood clot hardens when exposed to air

    forming scab

    Difference between blood and lymph Type of immunity Phagocytosis

    - lymph has a large numbers of lymphocyte

    compare to blood

    - lymphocyte is produced by lymph nodes

    in lymph system

    - lymph has lower content of oxygen

    compare to blood

    - active immunity, body produces its own

    antibodies in response to stimulation by

    an antigen

    - passive immunity, body receive an

    antibodies from outside source

    - the phagocyte is attracted by chemicals

    produced by bacterium

    - Phagocytes extend its pseudopodium

    (legs) towards bacterium to engulf it.

    - ingestion of bacterium forms phagosome

    - phagosome combines with lysosome

    -lysosome releases lysozyme into

    phagosome

    - bacterium inside the phagosome will be

    destroyed by lysozyme

    - phagocyte releases the digested products

    from cell

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    Lymph formed - brought back into the blood

    circulatory system.

    Respiratorygases Active immunity Passive immunity

    - when blood flows from arteries into

    capillaries, there is higher hydrostatic

    pressure at artial end of capillaries

    - high pressure causes some plasma to pass

    through capillary walls into intercellular

    spaces

    - interstitial fluid fills the spaces between

    cells and constantly bathes the cells- 90% of interstitial fluid diffuses back into

    blood capillary

    - 10% of interstitial fluid goes into the lymph

    capillaries and known as lymph

    - lymph capillaries unite forming larger

    lymphatic vessels

    - from lymphatic vessels, lymph eventually

    passes into thoracic duct

    - hence lymph drains back into blood

    Transportation in respiratory gas.

    - oxygen enters alveoli during inhalation

    - gaseous exchange occurred at alveoli

    (oxygen diffused into blood capillaries

    while carbon dioxide diffused out)

    - the diffusion of these gases caused by

    different of partial pressure of both

    gaseous- partial pressure of oxygen in alveoli is

    higher than partial pressure of oxygen in

    blood capillaries

    - oxygen diffused in cytoplasm of red blood

    cell

    - oxygen combines with haemoglobin

    forming oxyhaemoglobin

    -oxyhaemoglobin then sent to all parts of

    body

    - heart pumped the oxygenated blood to all

    body cells

    - oxygen diffused from blood capillaries to

    cell because partial pressure of oxygen in

    blood capillaries is higher than in cell

    - carbon dioxide diffuse from cell to blood

    capillaries because partial pressure of

    carbon dioxide in cell is higher than in

    blood capillaries

    - deoxygenated blood going back to heart

    by vena cava and to lungs by pulmonary

    artery

    Active immunity

    - obtained by vaccination (artificially

    acquired)

    - vaccine contains dead/weakened

    bacteria/pathogen/virus

    - white blood cells stimulated to produce

    antibodies against pathogen

    -also obtained when an individual hasrecovered from certain diseases(naturally

    acquired)

    - a ready made supply of antibody will give

    immunity towards the disease

    Passive immunity

    - obtained by injecting

    antibodies/antiserum (artificially

    acquired)

    - no antigen is put into body, so body does

    not produce its own antibodies

    - obtained by a baby when antibodies from

    mothers blood plasma diffuse into foetus

    through placenta (naturally acquired)

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    Movement of water froom root toleaves Movement of water from root toleaves Effect of no lignin formation on the function of

    tissue xylem

    Movement of water from root to leaves aided by

    root pressure, capillary action and transpirational

    pull.

    Root pressure

    cell sap of root hair(usually) hypertonic to

    surrounding soil solution

    water diffuses into root by osmosis

    cell cap becomes more dilute compared

    to neighbouring cell

    water moves to these adjacent cells whichbecome more diluted themselves, so

    osmosis continues across the cortex

    (at the same time) ions from soil are

    actively secreted into xylem vessels and

    causes osmotic pressure to increase

    Water flows continuously into xylem and

    create a pressure(root pressure)

    Root pressure gives an initial upwardforce to water and mineral ions in xylem

    Capillary action

    water moves up through xylem in stems

    by capillarity

    capillary action is due to combined force

    of cohesion(water molecules have

    attraction for each other) and

    adhesion(water molecules are attracted

    to the side of vessels)

    water molecule form a continuous water

    column in xylem vessel (due to cohesion

    and adhesion) the cohesion of water prevent the water

    column in xylem breaking apart

    the adhesion of water prevents gravity

    from pulling the water down the column

    Transpirational pull

    the lost of water from mesophyll cells

    during transpiration is replaces by waterwhich flows in from xylem vessels in

    leaves

    this creates a tension/suction force in

    water column because water has cohesive

    properties called transpiration pull

    the transpiration pull draws water from

    xylem in the leaves/stem/roots

    the continuous flow of water through

    plant is known as transpiration stream

    lignin is important to make tissue xylem

    strong

    - without lignin, tissue xylem will collapse

    - therefore, it cannot form a continuous

    hollow tube

    - to allow water to flow upwards

    continuously

    lignin makes the tissue become

    impermeable

    - materials cannot pass in xylem cells

    - causes the tissue to become hollow

    - allows continuous flow of water

    -

    (choose one of the * and the explanations below)

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    light intensity and stomata and cells effect the

    rate of water loss

    Adaptation of the muscle which enables it to

    contracts

    Movement takes place involves muscles,

    tendons, bones, ligaments and joints

    F1- from 0500 to 0170(time/hours), rate

    of water loss increases

    E1- light intensity increases

    E2- stimulates photosynthesis in guard

    cells

    E3- this makes energy available for

    potassium to move into guard cells by

    active transport

    E4- guard cells become

    hypertonic(compared to cell sap) of

    epidermal cells E5- water molecules from epidermal cells

    diffuse into guard cells by osmosis

    E6- causing guard cells to bend outwards

    E7- stoma opens (allows water to escape)

    F2- from 0170 to 0300(time/hours) rate of

    water loss decreases

    E8- lisght intensity decreases/rate of

    photosynthesis decreases

    E9- guard cells become flaccid and bend

    inwards

    E10- stoma closes, prevents water from

    escaping

    Notes: (F1 + any 5Es) + (F2 + 3Es)

    - the skeletal muscle consist of bundles of

    muscle fibres and a large supply of nerves

    and blood vessels

    - a muscle fibre is made up of bundles of

    smaller units called myofibrils

    - each myofibril is made up of 2 types of

    protein filaments: the actin and the

    myosin which interact and cause muscle

    contractions

    - the muscles nerve endings control its

    contractions

    Muscle

    - quadriceps femoris contract while biceps

    femoris muscles relax (leg straightened)

    - biceps femoris contract while quadriceps

    femoris relax (leg bent)

    - calf muscles contract to lift up the heels

    - feet push downwards and backwards

    - repeated contraction and relaxation of

    muscle result in running movement

    Ligaments

    -

    it connects 2 bones together- give support and strength to joints for

    movement

    - strong and elastic

    Joints

    - a hinge joint allow the movement of leg to

    swing back and forth

    Tendon

    -connect muscles to bones

    - strong and non elastic

    - force is transferred to bones through

    tendons

    Bones

    - femur/ thigh bone is long, heavy and

    strong

    - provide support to body weight

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    Adaptation of plant which enable it to float Skeletal system of earthworm and fish adapted

    for its movement

    Adaptive features which helps in birds and fish

    locomotion

    - have fine aerenchyma wall tissues (plants

    become more lighter)

    - have air spaces/air sacs (becomes more

    easy to float)

    - have big and swell stem/petiole (increase

    the air to help plant floating)

    - have fine and many roots (trap gas

    bubbles)

    Movements in earthworm

    - earthworm has hydrostatic skeleton

    - moves by changing hydrostatic pressure

    of fluid in its segment

    - each segment of the body has its own set

    of muscles

    o an outer layer of circular muscles

    running around the body causes the

    worm to become long and thin when

    they contract

    o

    an inner layer of longitudinal musclescauses the worm to get short and

    thick when they contract

    - as the circular muscles contract, the

    longitudinal muscles will relax

    simultaneously in antagonistic action

    - causes the hydrostatic pressure to be

    transferred from anterior part to posterior

    part causing the worm to move forward

    Movements in fish

    - fish has an endoskeleton

    - it provides place for attachment of

    muscles

    - when the left myotome contracts, right

    myotome will relax in antagonistic action

    -causes the vertebral column to curvetoward the left

    - the fish also has fins with different

    functions for locomotion

    Bird

    - aerofoil wing to generate the upward lift

    - a pair of antagonistic muscle (pectorolis

    major and minor) pulled down and up the

    wings

    - single organ (one testes/kidney)//small

    skull to reduce weight

    - streamlined body shape reduce air

    resistance

    - waterproof feather avoid increase in

    body weight during rainingFish

    - streamed lined body reduce water

    resistance

    - myotome muscle are W/V shaped which

    act antagonistically

    - air sac maintain buoyancy in water

    - fins

    o

    dorsal and ventral fin prevent/helps in yawing and

    rolling

    o tail fin provides thrust and

    controls direction

    o pelvin and pectoral fin act as

    brakes/to slow down

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    Support is achieved in submerged and floating

    plants

    Osteoporosis and osteoarthritis happen -

    prevented

    Important to have healthy musculoskeletal

    system - ways maintaining a healthy

    musculoskeletal

    Submerged plants

    - posses air sacs within the leaves and the

    stem to help the plant to stay upright in

    water

    - water buoyancy provides support

    - have very few woody tissue/vascular

    tissue

    - thin/narrow/flexible leaves provide little

    resistance to water flow

    Floating plants- stem have plenty of air sacs

    - aerenchyma tissues helps to stay afloat in

    water

    - do not have woody tissues

    - natural water buoyancy to help them float

    - have broad leaves that are firm but

    flexible to resist being torned by wave

    action

    Osteoporosis

    - a disease in which bone mass is reduced

    and the boned become porous and lighter

    - occurse most often in old people, partially

    women who have gone menopause

    - bodies of postmenopausal women do not

    produce sex hormone, oestrogen

    - causes more bone minerals to be lost than

    deposited

    -

    as a results, bones become soft and brittle- can be prevented by

    o doing weight-bearing exercise,

    strengthen the muscles and bones

    o taking diet rich in calcium,

    phosphorus and vitamin D

    o takin in vitamin C, increase bone

    mass

    o

    refraining from smokingOsteoarthritis

    - Osteoarthritis is part of ageing process

    due to wear and tear of cartilage between

    bones at certain joints

    - Patient has painful, swollen stiff knees

    which restrict daily activities (walking,

    climbing)

    -If treatment fails to relieve the pain, asurgeon can replace the damaged joints

    with artificial ones made of plastic or

    metal

    The musculoskeleton system where bones,

    muscles, ligaments and tendons work together

    like a machine to bring about movement

    - musculoskeleton helps to support our

    body

    - if any part of system injured, we will

    experience discomfort, pain and loss of

    mobility

    -

    it also affect othe organs and physiologicalprocesses in body (respiration/digestion)

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    Important to have healthy musculoskeletal

    system - ways maintaining a healthy

    musculoskeletal

    Osteoarthritis and arthritis gout occur - effect of

    the diseases

    Support system in woody plants differs from that

    of non-woody plants

    Ways to maintain

    - having balanced diet. Take diet rich in

    proteins, vitamins A, C n D together with

    minerals (calcium,phosphate n iron) for

    building strong bones. Drinking

    fluoridated water will also harden the

    bones

    - adopt a good posture while standing,

    sitting, walking and while performing

    certain tasks to ensure that our body isalways supported. This is important

    because bad posture will put undue

    pressure on our muscles and spine and

    this will in turn affect the functions of our

    internal organs (lungs, heart and stomach)

    - wear proper attire for daily activities.

    Wear loose and comfortable clothes. Tight

    clothes restrict our movement. Womanwearing high heels tilt the body forwards.

    To counteract this, the woman bends her

    knees and throws her trunk forwards,

    causing the spine to curve even more

    - taking precautions during vigorous

    activities

    - practice correct and safe techniques when

    exercisingto prevent serious injuries tothe musculosketonn system

    Muscular dystrophy

    - muscle destroying disorder

    -weakness/weaking of muscles

    - mostly in male

    - affect the heart muscle heart attack

    - results in poor balance/wobbling/poor

    movement

    Osteoporosis

    - condition characterized by lost of normal

    density of bone- resulting in fragile bone

    - bone fracture

    - no symptom before any bone fracture

    - consequences fracture of

    vertebrae//reduction of in height over

    time//stooped posture

    Non-woody plants (herbaceous plants)

    - (support in herbaceous plants is) provided

    by the turgidity of

    parenchyma/collenchyma cells

    - (when there is enough warm in the

    ground) the cells take in water by osmosis

    and become turgid

    - The turgor pressure of fluids in the

    vacuoles pushes the cell contents/plasma

    membrane against the cell wall- Creating support for its tem/roots/leaves

    - The thin thickening die cell walls with

    cellulose/collenchyma cells gives support

    to herbaceous plants

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    Support system in woody plants differs from that

    of non-woody plants

    Synapse The event as a nerve impulse is

    transmitted across a synapse

    Knee jerk

    Woody plants

    - woody plants have specialized

    tissues/sclerenchyma tissues/xylem

    vessels.tracheids to give them support

    - these tissues have cellulose walls which

    have deposits of lignin for added strength

    - sclerenchyma cells have very thick walls

    (do not allow water to pass through)

    - (these cells are dead cells) their function is

    to provide support

    -

    Xylem vessels have thick walls of ligninwhich are deposited during the plants

    secondary growth

    - The lignified xylem vessels form the

    woody tissues of the stem

    - This makes the plant stronger and also

    provides support for the plant

    - Tracheids are also dead cells with thick

    walls and very small diameters- They are found with xylem vessels and

    together they support the plants

    Synapse is a narrow gap between an axon

    terminal and a dendrite of another

    adjacent neuron. A chemical is used by

    neuron to transmit an impulse across a

    synapse. The chemical is called

    neurotransmitter

    The transmission of information across a

    synapse involves the conversion of

    electrical signal into chemical signal in the

    form of neurotransmitter Neurotransmitter is produced in vesicles

    in a swollen part of the axon terminal

    called synaptic knob

    Synaptic knob contains abundant

    mitochondrion to generate energy for the

    transmission

    When an impulse arrived at the synaptic

    knob, the vesicles release theneurotransmitters into the synapse

    The neurotransmitters molecules diffuse

    across the synapse to the dendrite of

    another neurons

    The dendrite of another neurons is

    stimulated to trigger a new impulse which

    travel down a long neuron

    - the knee jerk action involves two types of

    neurons named afferent and efferent

    neurons

    -when a hammer hits a tendon that

    connect to quadriceps muscle in the thigh

    to a bone in the lower leg

    - as the hammer strike, the force stretches

    the quadriceps muscle and stimulates the

    stretch receptors in the muscles,

    triggering nerve impulse

    -

    afferent neurons transmit the informationto the quadriceps muscle and the muscle

    contracts swing the leg forward

    - if the patient is able to swing the leg

    forward, it indicates that the patients

    nerve system is still functioning

    - if there is no response, it shows that the

    patients nervous system fails to function

    properly

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    When the hand touches a hot object Roles of cerebellum and medulla oblongata -

    reflex action when finger being stung by a bee

    Glomerular filtrate formed

    - the heat on the object stimulates the

    nerve endings (receptors) in skin

    - impulses are triggered

    -impulses travel along the sensory/afferent

    neuron to spinal cord

    - in spinal cord, the impulses are

    transmitted first across a synapse to the

    interneurone and then across another

    synapse to the motor/efferent neurone

    At synapse- when an impulse reach a presynaptic

    membrane, it triggers the synaptic

    vesicles to release neutrotransmitter into

    the synaptic cleft

    - the neurotransmitter diffuse across the

    synaptic cleft

    - and bind to receptors which are attached

    to the postsynaptic membrane- the binding of the neurotransmitter to the

    receptors leads to the generation of a

    new impulse

    - impulses leave the spinal cord along the

    motor/efferent neurone to the effector

    - the effector is the biceps muscle which

    then contracts. This brings about a sudden

    withdrawal of the hand

    Cerebellum

    - coordination of movement

    - controls of balance/posture

    Medulla oblongata

    - controls/increase breathing

    - controls/increase heart rate

    - controls blood pressure/sweating

    Reflex action

    - receptors in the skin of the finger detects

    pain

    -

    nerve impulse is generated in painreceptor

    - electrical impulses are sent via the

    afferent(sensory) neurone to spinal cord

    - impulses are transferred to the

    interneurone in the spinal cord

    - interneurone sents impulses to the

    efferent neurone

    -efferent neurone sents impulses tobiceps/muscle

    - biceps/muscle contract (triceps relax)

    causing the arm to bend

    - when blood enters the glomerulus,

    ultrafiltration takes place

    - because blood from the aorta reaches the

    nephron/glomerulus at high pressure

    - and due to the different artiole and

    efferent arteriole

    - the high pressure forces fluid through the

    filtration membrane into capsular space

    forming glomerular filtrate

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    Structure and the role of nephron - formation of

    urine

    Formation of urine Consequences of kidney failure

    Structure and the role of nephron

    - nephron is the functional unit of a kidney

    - a nephron consist of 3 major parts

    (glomerulus, and its associated vessels)

    - the Bowmans capsule

    - a long narrow tube called the renal

    tubule, which made up of proximal

    convoluted tubule, loop of Henle and

    distal convoluted tubule

    - the distal convoluted tubules of several

    nephrons join to a common collecting

    duct

    - the loop oh Henle is a long hairpin-shaped

    region of the nephron that descends into

    the medulla and then returns to the

    cortex

    - ultrafiltration, reabsoprtion and secretion

    - blood is under relatively high pressure

    when it reaches the nephron

    -high blood pressure in glomerulus, forces

    fluid to filter through the filtration

    membrane into the lumen of Bowmans

    capsule

    - forming glomerular filtrate

    - contains water, glucose, amino acids,

    mineral salts and other small molecules

    - the glomerular filtrate will flow into

    proximal convoluted tubule

    - selective reabsoption occurs

    - by active and passive transport

    - forming relatively high solute

    concentration in the peritubular

    capillaries

    - thus large volume of water is reabsorbed

    into the blood by osmosis- increase the concentration of urea in the

    convoluted tubule

    - glomerular filtrate then flow into loop of

    henle and distal convoluted tubule

    - more water and minerals being

    reabsorbed back into the blood

    - take place in the distal convoluted tubule

    -urea/toxins/ammonia/ect being secretedby passive diffusion and active transport

    from blood capillary into distal convoluted

    tubule

    - filtrate reaches the collecting duct (now

    called urine). flows down the ureter, the

    bladder and urethra and is finally excreted

    - if both kidneys stop functioning, the blood

    osmotic pressure and blood volume

    cannot be maintained

    -the built up of toxic wastes in the body

    can result in life-threatening conditions

    - they have to undergo haemodialysis

    - another treatment for impaired kidney

    functions is the transplant of a healthy

    kidney from a donor to the patient

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