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    Biomedical Sciences Program

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    States Funding Development of

    Biomedical Sciences Program:Connecticut

    Indiana

    Maryland

    Missouri

    Ohio

    Oklahoma

    South Carolina

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    PLTW Biomedical Sciences Program

    Address impending critical shortageof qualified science and health

    professionals.

    Prepare students for rigorous post-

    secondary education at two andfour-year colleges or universities.

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    Biomedical Careers

    --- some examples ---Doctor

    Nurse

    Dentist

    Veterinarian

    Pharmacist

    Paramedic

    Dietician

    Surgeon

    Research Scientist

    Health InformationManager

    Medical Technologist

    Radiologist

    Medical TechnicalWriter

    Physicians Assistant

    Biomedical Engineer

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    Sequence of Courses

    Principles of the BiomedicalSciences

    Human Body Systems

    Medical Interventions

    Science Research

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    Standards-Based

    National Science Education Standards

    Principles and Standards of SchoolMathematics

    National Health Care Cluster FoundationStandards

    Standards for English Language Arts

    Standards for Technological LiteracyNational Content Standards for Engineeringand Engineering Technology*

    * Once finalized

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    Curriculum Attributes

    Rigorous and Relevant

    Aligned with National Standards

    Project and Problem-based

    Integrate biology, chemistry, andphysics

    Integrate science, mathematics,English language arts, and socialstudies

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    Evaluation 6

    DHigh Rigor

    High Context

    Synthesis 5

    Analysis 4

    Application 3

    ALow RigorLow Context

    BLow Rigor

    High Context

    Understanding2

    Awareness 1

    1 2 3 4 5

    Knowledge Apply in

    discipline

    Apply

    acrossdisciplines

    Apply to

    predictable

    real-worldsituations

    Apply to

    unpredictable

    real-worldsituations

    Adapted from W. Daggett

    Application Model

    Blooms

    Levels of

    Learning

    CHigh Rigor

    Low Context

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    The Four Courses

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    Course #1: Principles of the

    Biomedical SciencesStudent work involves the study of humanmedicine, research processes and anintroduction to bio-informatics.

    Students investigate the human bodysystems and various health conditions

    including: heart disease, diabetes, sickle-cell disease, hypercholesterolemia, andinfectious diseases.

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    Course #2:

    Human Body SystemsEngage students in the study ofbasic human physiology, especially

    in relationship to human health.

    Students will use LabVIEWsoftware to design and buildsystems to monitor body functions.

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    Course #3:

    Medical InterventionsStudent projects will investigatevarious medical interventions that

    extend and improve quality of lifeincluding: gene therapy,pharmacology, surgery, prosthetics,rehabilitation, and supportive care.

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    Course #4:

    Scientific ResearchStudents will identify a scienceresearch topic, work with a mentor

    from the scientific or medicalcommunity to conduct research,write a scientific paper, and defend

    their research conclusions to apanel of outside reviewers.

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    Attributes of Graduates

    Think creatively and critically.

    Able to problem-solve.

    Communicate effectively.

    Have professional conduct.

    Able to work in teams.

    Understand how scientific researchis conducted, applied, and funded.

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    Principles of the BiomedicalSciences Course

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    Key Biological Concepts:

    Cellular basis of life

    Homeostasis

    Metabolism

    Inheritance of traits

    Defense against disease

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    Key Engineering Concepts:

    Process of design

    Feedback loops

    Fluid dynamics

    Relationship of structure to

    function

    Systems

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    Examples of Student Work

    Activities:build skills andknowledge

    Projects:build team work and allowstudents to practice the skills andknowledge with a real-world task

    Problems:build problem-solvingskills, team work, encouragecreativity, and allow students toapply skills and knowledge

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    Examples of Student Activities from

    Unit 2: Heart AttackBuild a simple pump

    Measure factors that affect pump

    efficiency

    Dissect a sheep heart

    Use LabVIEW software and Vernierprobes to measure EKG, heart

    rate, and blood pressure

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    LabVIEW Front Panel

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    LabVIEW Block Diagram

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    Examples of Student Activities from

    Unit 4: Sickle Cell DiseaseMake a chromosome spread

    Isolate DNA from plant cells

    Analyze karyotypes

    Build models of DNA and proteins

    Read a genetic map

    Use computer simulation software

    to build a designer protein

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    3-D Model of a Blood Protein

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    Curriculum Development Team

    David BartlesAntonella Bona

    Beth Chagrasulis

    Alan Dinner, Ph.D.Susan Gorman, Ph.D.

    Nicholas Greer

    Peggy Hinzman

    Angela Hopkins

    Tara Johnson

    Jane King

    Carolyn Malstrom, Ph.D.Tonya Mathews, Ph.D.

    Marva Moore

    Susan Moore-PalumboStephanie Poll

    Donna Putnam

    Jean Schick

    Angie Snyder

    Tony Valentino, Ph.D.

    Gene Williams

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    Curriculum Review

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    Reviewers:

    Sarah Davis:Middle school scienceteacher and consultant for Education

    Development CorporationJames Potter:Research Associate inHepatology at Johns Hopkins

    UniversityMeredith Durmowicz, Ph.D.:Chairperson, Department of Biology,Villa Julie College

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    Curriculum Review Scoring Tool

    Scored 93 separate characteristics from

    1 (not present) to 4 (no revision necessary)

    Rigor and relevanceAlignment of Key Concepts, Essential

    Questions, National Standards, Performance

    Objectives, and actual student work

    Vertical alignment to post-secondary educationalrequirements

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    Reviewers Scores:

    The average total score of theratings from the reviewers was 3.5.

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    Reviewers Comments:

    Jim Potter:The curriculum is verywell designed and certainly

    provides rigor for a 9th gradecurriculum. I was extremelyimpressed with the scope of thedocument. It is unusual for a 9th

    grade science curriculum.

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    Reviewers Comments:

    Meredith Durmowicz:The activitiesoffer a wide range of types of

    learning styles and activities,including visual (reading), tactile,oral, and graphically orientedactivities. There are many

    opportunities for students to drawconnections and demonstrateunderstanding in many differentways.

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    Implementation

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    Field Test 2007-2008

    In 42 schools selected by the StateDepartments of Education or

    Workforce Development in theseven funding states.

    Same schools will field test eachnew course as it is released.

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    Expansion of Program

    2008Expand field test implementation of

    first course into additional schools within

    the original states2009First course fully implemented

    nationally including:

    End-of-course examPurchase manualnational bid process