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Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpre t To make Decisions E_Mail: [email protected]

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Page 1: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Biostatistics ZMP 602Mathematical tools used to Collect

Organize

Analyse

Present

InterpretTo make Decisions

E_Mail: [email protected]

Page 2: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

TYPES OF STATISTICS

To Organize, Display, Describe data using

tables, graphs

Use information from descriptive statistics to make decisions or predictions about a population

Descriptive Inferential

Page 3: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Statistical Terms

All sets of individuals, items, or objects whose the characteristics being studied.

A selected portion from the studied population

Population

Sample

Population

Sample

Page 4: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Types Of Variables

CAUSE (Factor)

(Independent Variable) EFFECT (Response)

( Dependent Variable)

According to causal relationship

VariablesThe characteristics (quantities or qualities) that the individuals of a population possess.

Page 5: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

TYPES OF VARIABLESA. Quantitative Variables

Can be measured numerically (numeric variable)

Arithmetic operations (+, -, x, /)

Can be applied Are measured in a unit that can be subdivided infinitely

(Continuous Variables)

Ex: Age (in years)

Page 6: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

TYPES OF VARIABLES

• Scores are labels that Cannot be ranked

A.1. Nominal Level Variables

A. Qualitative Variables

Gender: male , Female

Race: White , Black

Religion: Muslim, Christian

Scores are labels that Cannot be treated as numbers

Measured in a unit that can not be subdivided infinitely (Discrete Variables)

Page 7: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

TYPES OF VARIABLES

• Scores are non-numerical forms and can be ranked

A.2. Ordinal Level VariablesA. Qualitative Variables

Grades: Good, Very good, Excellent

Medals: Gold, Silver, Bronze

Page 8: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Measures of Central Tendency •

 

 

Descriptive Statistics

Page 9: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Variance It is the arithmetic mean of the squared deviations from the mean of a

statistical distribution.

𝛔𝟐=(𝐱𝟏−𝐗 )𝟐+ (𝐱𝟐−𝐗 )𝟐+…+(𝐱𝐧−𝐗 )𝟐

𝐍

Squared Deviation

Sample Size

Page 10: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Standard deviation

It is the square rootof the variance (). 

Page 11: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Standard Error (S.E.) of Mean

It is the standard deviation of the sample mean divided by square root of sample size.

Page 12: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Freq

uen

cy

𝝁63.8%

−𝟏𝝈 −𝟐𝝈 −𝟑𝝈

95.5% 99.7%63.8%95.5%99.7%

+𝟏𝝈+𝟐𝝈+𝟑𝝈

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x

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Population

o Bell shapedo Smootho Symmetrical

Normal (Gaussian) Distribution Curve

Page 13: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

PopulationS2S1

SAMPLING

Sample 1

Sample 2

𝝁𝒊𝒔 𝒕𝒉𝒆𝑷𝑶𝑷𝑼𝑳𝑨𝑻𝑰𝑶𝑵𝒎𝒆𝒂𝒏𝝁

𝐗 𝒊𝒔𝒕𝒉𝒆𝑺𝑨𝑴𝑷𝑳𝑬𝒎𝒆𝒂𝒏

Page 14: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Bar Chart

Parameter Value Freq.

A 6B 4

AB 1O 9

A B AB O0

2

4

6

8

10

Frequency

Values of Variable

o It is used to present all types of variables.

PRESENTATION OF DATA

Page 15: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Pie Chartso A pie chart can be used to represent all types of variables, but is more commonly

used for categorical variables.

o The data is represented in a circle and the angle of each circular sector is proportional to the corresponding absolute frequency.

𝜶=𝟑𝟔𝟎∘

𝑵∗ 𝒇 𝒊

EXAMPLEo In a class of 30 students, 12 play basketball, 3 swim, 4 play

football and the rest do not practice any sport.S tud ents Ang le

Basketb a l l 12 144°

S w imming 3 36°

Foo tb a l l 9 108°

No sp o r t 6 72°

To ta l 30 360°

Page 16: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

Basketball Swimming Football No sport

Page 17: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

HISTOGRAMSo A histogram is a graphic representation of a variable in the

shape of bars (rectangles).o They are used for all types of variables with a large quantity of

data that is grouped into classes.o The base width of the bars (rectangles) are proportional to the

class widths and the height is the absolute frequency of each interval.

o The surface area of every bar is proportional to the frequency of the represented values.

c i f i F i

[50, 60) 55 8 8

[60, 70) 65 10 18

[70, 80) 75 16 34

[80, 90) 85 14 48

[90, 100) 95 10 58

[100, 110) 110 5 63

[110, 120) 115 2 65

65

Page 18: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

6050 70 80 90 100 110 120

16

14

12

10

8

6

4

0

2

Freq

uen

cy HISTOGRAM

POLYGON

Class intervals

Page 19: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

40 50 60 70 80 90 100 110 1200

10

20

30

40

50

60

70

X-Y Scatter Chart

Page 20: Biostatistics ZMP 602 Mathematical tools used to Collect Organize Analyse Present Interpret To make Decisions E_Mail: Atef@Sci.cu.edu.eg

BASIC STATISTICAL INFERENCEHYPOTHESIS TESTS ON THE MEAN

𝝁 :

TEST THE NULL HYPOTHESIS 𝑯𝟎 :𝝁=𝝁𝟎

𝝁𝟎 :

𝑯 𝑨 :𝝁>𝝁𝟎 , 𝑯 𝑨 :𝝁<𝝁𝟎 , 𝑯 𝑨 :𝝁≠𝝁𝟎 ,

Inferential Statistics