bipaa resources for genome annotation · annotation search for your favorite gene (e.g. gustatory...

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BIPAA resources for genome annotation [email protected] http://bipaa.genouest.org

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Page 1: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

BIPAA resourcesfor genome annotation

[email protected] http://bipaa.genouest.org

Page 2: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

INRA platform in Rennes (French National Institute for Agricultural Research)

Three full-time engineers

- Anthony Bretaudeau- Fabrice Legeai- Stéphanie Robin

Supports (post)genomic projects on insects associated to agroecosystems

- Omics data analysis- Information systems

Page 3: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

AphidBaseLepidoDB

ParWaspDB

Today:

- Aphidius ervi- Aphis glycines- Daktulosphaira vitifoliae- Lysiphlebus fabarum

More to come, same environment

Page 4: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Information systemsMain website: http://bipaa.genouest.org

Published genomes

No account needed

Unpublished genomes

BIPAA account http://bipaa.genouest.org/account/

Per project credentials

Page 5: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Information systemFor each genome:

- Reference assembly- Reference structural annotation

- OGS = Official Gene Set- Automatic (with Maker)- Based on RNASeq, transcript/protein alignments from related species, …- Associated functional annotation (Blast vs NR, InterProScan, Blast2GO, …)

- Home page giving access to web services- Transcript/polypeptide reports (Tripal)- JBrowse- Apollo- Galaxy- Blast- Download page

Page 6: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Released data: assembly, structural and functional

annotation

Search for your favorite gene

(e.g. gustatory receptor,

DV000053-RA, GO id, …)

Availables services for this genome

Page 7: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Links to reports

Example search result: “gustatory”

Page 8: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example polypeptide report

Page 9: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example polypeptide report: Alignments

Links to JBrowse and Apollo

Page 10: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example polypeptide report: Blast vs NR

Detailed alignment

Link to GenBank

Page 11: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example polypeptide report: InterProScanLooks for known motifs in peptide sequences (gene families, catalytic sites, …)

Page 12: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example polypeptide report: InterProScan

Links to InterPro pages

and/or external databases

Page 13: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example polypeptide report: GO annotation

Links to terms description

Page 14: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Example mRNA report

Page 15: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Number of genes per GO-term

Global distribution

Download sequences

Page 16: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Query sequence

Reference sequences

Page 17: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Links to JBrowse, Apollo or gene reports

Download raw results

Page 18: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports
Page 19: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports
Page 20: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports
Page 21: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Download raw reference data

Fasta, GFF, functional annotation, ...

Page 22: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Common analysis tools (clustal, exonerate, RNASeq analysis, …)

Ready-to-use workflows

Page 23: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Reference data in the Data libraries

Page 24: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

What’s next?More genomes!

More features!

- Orthology- Links from each gene to orthologs in other species (BIPAA-hosted, external, OrthoDB)- OrthoMCL/OrthoDB/...

- Expression tables- Synteny

More data! Send us new RNASeq or alignments data to ease annotation!

More user-friendliness! Working on improving the web UI

Page 25: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

What’s next?AskOmics

Web application for data integration and querying (RDF, SPARQL)

http://github.com/askomics/askomics

Hands-on workshop

10th Arthropod Genomics Symposium - Arthropod Bioinformatics Workshop

June 8th 2017

Eck Institute for Global Health

University of Notre Dame

Page 26: BIPAA resources for genome annotation · annotation Search for your favorite gene (e.g. gustatory receptor, DV000053-RA, GO id, …) Availables services for this genome Links to reports

Getting in touchFeedback and suggestions highly appreciated!

We post news on http://bipaa.genouest.org

[email protected] for any question/feedback!