963

Chichester, Graylingwell Hos2.-Leputy med. supt., ,c700.Coventry and Warwickshire Hosp,-Three H.S.’s to special depts.,

each at rate of .6150.Croydon General Hosp.-Hon. asst. to surgeon in charge of the

urological and proctological dept. Also two hon. asst.surgeons.

Exeter, Wonford House Registered Hosp.-Asst. M.O., ,c350,Gloucester, Barnwood House Hosp. for Mental and Nervous

- DMOfefS.—Second asst. M.O., ,c450.Halifax Royal jK)Kaf!/.—First H.S., at rate of 200.Hastings, Royal East Sussex Hosp.-Sen. H.S., at rate of ,c200.Hertford County Hosp.-Hon. asst. surgeon.Hosp. for Sick Children, Great Ormond Street, W.C.1.—Out-

patient med. reg., £150.Ipswich, East Suffolk and Ipswich Hosp.-Res. surg. 0., 9400

single man, 9550 married man.Kent County.—Two asst. county M.O.H.’s, each £700.King Edward Memorial Hosp., Ealing, W.13.-Cas. O. and

H.S., at rate of £150.King’s College Hosp., Denmark Hill, S.E.5.-Asst. physician to

diabetic dept.Lancashire County Council.-Asst. county M.O., ,c800. Also

jun. H.S. at Biddulph Grange Orthopædic Hosp., at rateof .82 00.

Lancaster, Royal Albert Institution for the Feeble-minded.-Res.Jun. asst. M.O., .8375.

Leeds City.-Asst. to the M.O.H., £600.Leicester Royal Infirmary.—Res. radiologist, at rate of .8200.Lincolnshire Joint Board for the Mentally Defective.-Asst. M. 0.,

£350.Liverpool, Smithdown Road Hosp.—Res. asst. M.O., £200.London County Council.-Asst. M.O., Class I, .8350. Also

asst. M.O., Class II, £250.London Lock Hosp., 283, Harrow Road, W.9.-Res. M.O. to

all depts., at rate of £175.London University.-University chair of obstetrics and gynæco-

logy, £2000.Manchester, Monsall Hosp. for Infectious Diseases.-Jun. res.

asst. M.O., at rate of 250.Manchester, Withington Hosp.—Deputy med. supt., £600.Manchester City Education Committee.—School M.O., &1000.Manchester Ear Hosp., Grosvenor Square, All Saints’.-Visiting

anaesthetist.Manchester Royal Children’s Hosp., Pendlebury.-Asst. surgeon,

£50.Middlesbrough, North Riding Infirmary.—H.P., at rate of £140.Middlesex County Council.-Asst. M.O. for public health and

school medical department, .8600. Also asst. M.O. forRedhill County Hosp., £400.

National Dental Hosp., Great Portland Street, W.1.—Hon.dental surgeon.

Neavcastle-2cpon-Tyne, King’s College.-Asst. bacteriologist inpublic health laboratory, 400.

Norwich, Norfolk and Norwich Hosp.—H.S. to spec. depts.,£160. Also cas. 0., £120.

Nottingham, Mapperley Hosp.—Locum tenens M.O., 7 guineasper week.

Nottingham, The Coppice.—Locum, 7 guineas weekly.Paddington Green Children’s Hosp., W.2.-Hon. radiologist.Pontefract General Hosp., &c.-Jun. res. M.O., at rate of £150.Prince of Wales’s General Hosp., N.15.-Hon. officer to speeeh-

therapy and lip-reading dept. Also hon. dental surgeon.Princess Beatrice Hosp., Earl’s Court, S.W.5.-Hon. asst.

surgeon to ophth. dept.Princess Elizabeth of York Hosp. for Children, Shadwell, E.I.-

Hon. neurological surgeon.Public Schools Exploring Society.-Hon. surgeon for Newfound-

land Expedition.Putney Hosp., Lower Common, S.W.15.-Hon. physician. Also

res. M.O., £150.Reading Royal Berkshire Hosp.-Snrg. reg.Redhill, Surrey, Royal Earlswood Institution.-Jun. asst. M.O.,

£350.Rotherham Hosp.-H P., £180.Royal Naval Medical Sertgce.-M.O.’i3.Royal Northern Hosp., Holloway, N. 7.-Consulting physicist.Royal Waterloo Hosp. for Children and Women, Waterloo Road,

S.E.1.-Res. M.O., at rate of £150. Also H.P. and H.S.,each at rate of £100.

Salop County Council.-Deputy county M.O.H. &c., 700.Also asst. M.O.H., &c., £600.

Samaritan Free Hosp. for Women, Marylebone Road, N.W.1.—H.S., at rate of £100.

Sheffield Children’s Hosp.-H.S., at rate of £100.Shoreditch Metropolitan Borough.-Asst. M.O.H., £650.Slough Borough, &c.-Deputy M.O.H. and deputy M.O. of

hosp., £500.Stafford, Staffordshire General Infirmary.—H.S. and H.P.,

at rate of £175 and "150 respectivelyTorquay, Torbay Hosp.—Hon. physician in charge of outpatients.Virginia Water, Surrey, Holloway Sanatorium.-Jun. asst.

M.O., £350.Wembley Borough.-Asst. M.O.H., £500.West London Hosp., Hammersmith, W.6.—Children’s outpatient

M.O., at rate of £150. Also res. anaesthetist, at rate of £100.Westminster Hosp., Broad Sanctuary, S.W.1-Chief asst. and

registrar to electrical and irradiation unit, £ 250. Part-timechief asst. and registrar to radiological department, £150.Also additional offices from ,cl00 to £350.

West Sussex County Council.—Asst. county M.O.H. and districtM.O.H., £800.

Wolverhampton Royal Hosp.-H.S. to fracture and orthopaediedepartment, at rate of £100.

Woolvrich and District War Memorial Hosp., Shooters Hill, S.E.18.H.P., at rate of .8100.

The Chief Inspector of Factories announces vacancies forExamining Factory Surgeons at Bothwell (Lanark) andNelson (Glamorgan).

Births, Marriages and DeathsBIRTHS

ASHEEN.—On April 11, at Stanmore, Middlesex, the wife ofDr. L. Handley Ashken-a daughter.

MOCKLER.—On April 14, at Welbeck Street, W.1, the wife ofSurgeon Lieut.-Commander Edmond J. Mockler, R.N.-a daughter.

MORTON.—On April 11, at Brentwood, the wife of Dr. RichardBertram Morton-a daughter.

SINCLAIR.—On April 16, at Lewes, the wife of Mr. C. GordonSinclair, F.R.C.S.-a son.

MARRIAGESBEOEETT—HATNES.—On April 12, at St. Benet’s Church,

Cambridge, Francis George Archer Beckett, M.B., to LucyDaville Haynes.

OAMPBELL—ERWIN.—On April 12, at Antrim, Robert TaitCampbell, M.B., Sudan Medical Service, to Lilian WinifredErwin.

DUNOAN—HOLLIDATT.—On April 12, at St. Andrew’s ParishChurch, Penrith, Archibald Sutherland Duncan, M.B., toBarbara Holliday.

DEATHS

BATES.—On April 17, at St. Albans, Henry Leslie Bates,M.R.C.S., aged 90.

SCoTT.-On April 12, at Wentworth, Virginia Water, JosephScott, M.B. Glasg.

N.B.-A fee of 7s. 6d. is charged for the insertion of NoticeR ofBirths, Marriages, and Deaths.

RUSSIAN WORK ON LYSOZYME

LYSOZYME was discovered and named by A.Fleming, who described it as " a ferment-like substancewhich has the power of killing and dissolving bacteria,and which is widely distributed throughout thebody " (Lancet, 1929, 1, 217). During the last sixyears it has been elaborately studied by Z. W.Yermoljeva and I. Bouianowskaja, who have foundit in the tears, sputum, saliva, serum, plasma,leucocytes, ova, heart, liver, lungs, kidneys, andspleen of different animals (Acta med. U.R.S.S.1938, 1, 249). The tissues and body fluids of man,especially cartilage and tears, are, they say, very richin it; indeed almost the only part of the human bodythat has none is the cerebrospinal fluid. Accordingto this work in Moscow lysozyme acts equally wellwhether oxygen is present or not, and it lyses deadand living bacteria, whether saprophytic or patho-genic. There is, however, some specificity of actionaccording to the provenance of the lysozyme. Thisextends the specificity found by Fleming, whoisolated a coccus (Micrococcus lysodeikticus) so

sensitive to the action of lysozyme that he used it todetect the presence of the enzyme. As long ago as1931 Yermoljeva and Bouianowskaja used lysozymein the treatment of various affections of the ear,nose, and throat, and in the laboratory it is said tohave proved efficacious in the treatment of kerato-malacia in rats and of various diseases of skin, cornea,and conjunctiva in rabbits. It was found to stimulatecicatrisation and reabsorption, and Fradkin andBeketovsky are stated to have used it with successfor serpiginous ulcer of the cornea. In surgical workYermoljeva and Bouianowskaja have employed itinstead of antiseptics.

" ... It is commonly said that the pace of life hasincreased, and that there is a greater strain upon thenervous system of the modern man and woman. If thisbe so, how can it be explained ? One important reason isprobably the development of the internal combustionengine, which Philip Gibbs regards as ’the most destruc-tive agent of ancient peace, present beauty and futuresafety.’ ’Thirty years ago,’ he says, ’if the schoolboywere five minutes late for his tea, his mother did notturn pale and go to her cottage door with panic in herheart. If the husbandman came home even an hour latebecause he had stopped for a glass of ale in the ThreeHorseshoes, his wife did not expect his corpse to be broughtto her on a stretcher.’ "-K. B. NOAD, Med. J. Aust.,Feb. 25, p. 294.